Antiparassitari
Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.
Trovati 704 prodotti di "Antiparassitari"
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GNF179
CAS:<p>GNF179 is an optimized 8,8-dimethyl IP analog.</p>Formula:C22H23ClFN5OPurezza:98.9%Colore e forma:SolidPeso molecolare:427.9HAT-IN-8
<p>HAT-IN-8 (Compound 38), a blood-brain barrier-permeable inhibitor of Trypanosoma brucei with an EC50 of 0.18 μM, is utilized in the study of Human African</p>Formula:C14H15F2N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:327.35Nanaomycin A
CAS:<p>Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).</p>Formula:C16H14O6Purezza:98%Colore e forma:SolidPeso molecolare:302.28Antitrypanosomal agent 16
<p>Antitrypanosomal agent 16 functions as a potent trypanocide, exhibiting an inhibitory concentration 50 (IC50) of 0.04μM against the T.</p>Purezza:98%Colore e forma:Odour SolidAntileishmanial agent-21
<p>Antileishmanial agent-21 (compound 4e) functions as an inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1), employing an anti-folate mechanism.</p>Formula:C21H16N2O3Purezza:98%Colore e forma:SolidPeso molecolare:344.36Alkaline tryptase-IN-1
<p>Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.</p>Formula:C29H33BrN2O2SColore e forma:SolidPeso molecolare:553.55Antimalarial agent 31
<p>Compound 31 (compound 7k) is an orally active inhibitor of Plasmodium falciparum aspartic protease, plasmepsin X (PMX), with antimalarial properties [1].</p>Formula:C36H47N3O4Purezza:98%Colore e forma:SolidPeso molecolare:585.78Antitrypanosomal agent 17
<p>Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1].</p>Purezza:98%Colore e forma:Odour SolidCinchonidine
CAS:<p>Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.</p>Formula:C19H22N2OPurezza:94.96% - 99.87%Colore e forma:White PowderPeso molecolare:294.39Antiparasitic agent-17
<p>Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-</p>Formula:C32H30N2O4Purezza:98%Colore e forma:SolidPeso molecolare:506.59Antileishmanial agent-19
<p>Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L.</p>Formula:C22H18N4O3Purezza:98%Colore e forma:SolidPeso molecolare:386.4Anticancer agent 140
<p>Compound 140 (Compd 3) exhibits potential anticancer and antiparasitic activities [1].</p>Formula:C20H26N2OPurezza:98%Colore e forma:SolidPeso molecolare:310.43SpdSyn binder-1
CAS:<p>SpdSyn binder-1 weakly inhibits malaria by binding to Plasmodium falciparum's spermidine synthase. Used for research.</p>Formula:C21H22N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:346.43Antileishmanial agent-20
<p>Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L.</p>Formula:C15H16N4O3Purezza:98%Colore e forma:SolidPeso molecolare:300.31ML251
CAS:<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Formula:C17H13Cl2N3O4SPurezza:99.87%Colore e forma:SolidPeso molecolare:426.27Antiparasitic agent-20
<p>Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T.</p>Purezza:98%Colore e forma:Odour SolidCpNMT-IN-1
<p>CpNMT-IN-1 (Compound 11e) is an inhibitor of N-myristoyltransferase (CpNMT) with an IC50 value of 2.5 μM. It also inhibits the growth of microsporidia, demonstrating an EC50 value of 6.9 μM.</p>Formula:C25H25ClN4O4SColore e forma:SolidPeso molecolare:513.008Antiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Colore e forma:Odour SolidAntitrypanosomal agent 23
<p>Antitrypanosomal agent 23 is an antiparasitic compound effective against intracellular amastigotes of Trypanosoma cruzi in LLC-MK2 and C2C12 cells, demonstrating activity with IC50 values of 0.10 and 0.11 μM, respectively. It also acts as a weak inhibitor of recombinant Trypanosoma cruzi sialyltransferase (TcTS) with an IC50 of 1.1 mM.</p>Formula:C14H16N4O7Colore e forma:SolidPeso molecolare:352.1019Cletoquine
CAS:<p>Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.</p>Formula:C16H22ClN3OPurezza:99.95% - 99.98%Colore e forma:SolidPeso molecolare:307.82Emoquine-1
<p>Emoquine-1 is a potent orally active antimalarial agent effective against various drug-resistant Plasmodium strains, including artemisinin-resistant dormant parasites. It demonstrates efficacy against proliferative malignant Plasmodium with an IC50 value ranging from 20 to 55 nM. Emoquine-1 holds potential for treating Plasmodium strains resistant to artemisinin combination therapy (ACT), with the capability to eradicate persistent parasites.</p>Formula:C30H28ClN3O6Colore e forma:SolidPeso molecolare:562.013Antitrypanosomal agent 12
<p>Antitrypanosomal agent 12, a C20-phenylthiourea, exhibits trypanocidal and cytotoxic activities, demonstrating antitrypanosomal activity with GI50 values of 0.</p>Formula:C49H77N2NaO10SPurezza:98%Colore e forma:SolidPeso molecolare:909.2Anti-inflammatory agent 40
<p>Anti-inflammatory agent 40 is a promising, orally-active compound with anti-malarial and anti-inflammatory properties.</p>Formula:C30H24Cl2N2O4Purezza:98%Colore e forma:SolidPeso molecolare:547.43Norselic acid B
CAS:<p>Norselic acid B is a naturally occurring compound that can be isolated from the sponge Crella sp. collected in Antarctica. It demonstrates activity against Leishmania parasites.</p>Formula:C29H44O4Colore e forma:SolidPeso molecolare:456.657Antimalarial agent 47
<p>Antimalarial agent 47 (compound F14) is a chemical compound effective against Plasmodium falciparum, specifically targeting the W2 strain with an IC50 value of 235 nM.</p>Formula:C16H14ClF2NOColore e forma:SolidPeso molecolare:309.74LASSBio-1985
<p>LASSBio-1985 is an inhibitor of NHLd (nucleoside hydrolase of Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. It exhibits selective toxicity against Leishmania parasites without affecting mammals, showing potential for research in infectious disease treatment.</p>Formula:C18H22N2O7Colore e forma:SolidPeso molecolare:378.38Antileishmanial agent-24
<p>Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM against</p>Formula:C34H29Cl4N3O2Purezza:98%Colore e forma:SolidPeso molecolare:653.42AAP4
<p>AAP4 is a potent inhibitor of OfChi-h and OfHex1, exhibiting Ki values of 29.3 nM and 4.9 μM, respectively. It also demonstrates insecticidal activity against the lepidopteran pest Ostrinia furnacalis.</p>Formula:C21H23BrClN7Colore e forma:SolidPeso molecolare:488.811Antiproliferative agent-56
<p>Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.</p>Colore e forma:Odour SolidNitroxynil
CAS:<p>Nitroxynil is an anthelmintic for adult/immature parasites, mainly used in Fasciola hepatica studies.</p>Formula:C7H3IN2O3Purezza:99.76%Colore e forma:SolidPeso molecolare:290.01Antileishmanial agent-25
<p>Antileishmanial agent-25 (compound 24) exhibits selective activity against intracellular amastigotes, demonstrating an inhibitory concentration (IC50) of 6.63</p>Purezza:98%Colore e forma:Odour SolidAntimalarial agent 43
<p>Antimalarial agent 43 (compound 16c) is an antimalarial compound that exhibits an IC50 value of 0.0151 μM against the 3D7 strain.</p>Colore e forma:Odour SolidDoxycycline monohydrate
CAS:<p>Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)</p>Formula:C22H26N2O9Purezza:98.87%Colore e forma:SolidPeso molecolare:462.4Urethane
CAS:<p>Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.</p>Formula:C3H7NO2Purezza:99.01%Colore e forma:SoildPeso molecolare:89.09Antimalarial agent 28
<p>Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P.</p>Formula:C27H25ClFN3O2Purezza:98%Colore e forma:SolidPeso molecolare:477.96Amprolium
CAS:<p>Amprolium is a veterinary coccidiostat that interferes with THIAMINE metabolism.</p>Formula:C14H19N4·ClPurezza:98%Colore e forma:SolidPeso molecolare:278.79Schizophyllan
CAS:<p>Schizophyllan, a member of the β-glucan family, is an extracellular polysaccharide known for its antitumor, antibacterial, and antiparasitic activities.</p>Colore e forma:SolidIle-AMS TFA
<p>Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.</p>Formula:C18H27F3N8O8SColore e forma:SolidPeso molecolare:572.52Mepartricin
CAS:<p>Mepartricin, a polyene macrolide, exhibits both antifungal and antiprotozoal activities and is extensively utilized in studies related to benign prostatic hyperplasia.</p>Colore e forma:SolidGypsogenic acid
CAS:<p>Gypsogenic acid, a triterpenic acid isolated from Miconia stenostachya, exhibits antibacterial and antitrypanosomal activities. This compound demonstrates minimum inhibitory concentrations (MICs) ranging from 50-200 μg/mL against oral bacterial pathogens including Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus spp., and Streptococcus sobrinus. Additionally, gypsogenic acid can induce the lysis of Trypanosoma cruzi in isolated mouse blood, with an IC50 value of 56.6 μM.</p>Formula:C30H46O5Colore e forma:SolidPeso molecolare:486.684-(2-Aminoethyl)amino-7-chloroquinoline
CAS:<p>4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) has potential anthelmintic and antitumor activity for the study of</p>Formula:C11H12ClN3Purezza:98.53%Colore e forma:SolidPeso molecolare:221.69Febrifugine dihydrochloride
CAS:<p>Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory</p>Formula:C16H21Cl2N3O3Purezza:98.27% - 99.85%Colore e forma:SolidPeso molecolare:374.26TSO-13
<p>TSO-13 is an inhibitor of the major cysteine protease Cruzipain found in Trypanosoma cruzi, with an IC50 of 2.2 μM. In Vero cells, TSO-13 also suppresses T. cruzi, exhibiting an IC50 of 1.9 μM.</p>Formula:C32H36N4O4S2Colore e forma:SolidPeso molecolare:604.78Azlocillin sodium salt
CAS:<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>Formula:C20H22N5NaO6SPurezza:97.63% - 98.302%Colore e forma:SolidPeso molecolare:483.47Cysteine protease inhibitor-3
<p>Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM),</p>Formula:C26H22ClF2N3OPurezza:98%Colore e forma:SolidPeso molecolare:465.92DCN-83
<p>DCN-83, a potent anti-leishmanial compound, exhibits its highest efficacy against the amastigote form, achieving an IC50 value of 0.71 μM.</p>Formula:C20H18BrN3SPurezza:98%Colore e forma:SolidPeso molecolare:412.35Sulfadiazine
CAS:<p>Sulfadiazine, a short-acting sulfonamide, blocks bacterial folic acid synthesis; used with pyrimethamine to treat toxoplasmosis in AIDS, newborns.</p>Formula:C10H10N4O2SPurezza:99.32%Colore e forma:White To Slightly Yellow Crystalline PowderPeso molecolare:250.28Sarolaner
CAS:<p>Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).</p>Formula:C23H18Cl2F4N2O5SPurezza:99.54% - 99.65%Colore e forma:SolidPeso molecolare:581.36Se2h
<p>Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55). Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.</p>Formula:C12H13ClN4O2SeColore e forma:SolidPeso molecolare:359.67PfSUB1-IN-1
<p>PfSUB1-IN-1 (compound 4c) is an inhibitor of Plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1), exhibiting potent activity with an IC50 value of 15 nM. PfSUB1 is a key target in antimalarial research. PfSUB1-IN-1 demonstrates a 13-fold greater inhibitory effect on the growth of transgenic Plasmodium falciparum strains (expressing lower levels of PfSUB1 compared to the wild-type) than on wild-type parasite strains.</p>Colore e forma:Odour Solid
