Antiparassitari
Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.
Trovati 709 prodotti di "Antiparassitari"
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GNF179
CAS:GNF179 is an optimized 8,8-dimethyl IP analog.Formula:C22H23ClFN5OPurezza:98.9%Colore e forma:SolidPeso molecolare:427.9Ref: TM-T15409
1mg109,00€2mg158,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€Antimalarial agent 1
CAS:Antimalarial agent 1 is an effective antimalarial agent.Formula:C12H21N6O4PPurezza:99.04% - 99.59%Colore e forma:SolidPeso molecolare:344.31Doxycycline monohydrate
CAS:Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)Formula:C22H26N2O9Purezza:99.97%Colore e forma:SolidPeso molecolare:462.4Antiparasitic agent-17
Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-Formula:C32H30N2O4Purezza:98%Colore e forma:SolidPeso molecolare:506.59DXR-IN-1
DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). It exhibits high selectivity for DXR of Plasmodium falciparum with an IC50 of 0.030 μM. DXR-IN-1 impedes the growth of Plasmodium by binding to the active site of DXR and inhibiting its catalytic activity.Formula:C19H24NO5PPeso molecolare:377.13921TSO-13
TSO-13 is an inhibitor of the major cysteine protease Cruzipain found in Trypanosoma cruzi, with an IC50 of 2.2 μM. In Vero cells, TSO-13 also suppresses T. cruzi, exhibiting an IC50 of 1.9 μM.Formula:C32H36N4O4S2Colore e forma:SolidPeso molecolare:604.78Antiparasitic agent-20
Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T.Purezza:98%Colore e forma:Odour SolidNMT-IN-3
NMT-IN-3 is an inhibitor of N-myristoyltransferase (NMT), displaying an IC50 of 38 mM against Plasmodium vivax NMT.Formula:C26H32N6O4Peso molecolare:492.2485Diarctigenin
Diarctigenin is a selective inhibitor of Leishmania major dihydrofolate reductase-thymidylate synthase (LmDHFR-TS), and it is applicable in the study of tropical diseases.Formula:C42H46O12Peso molecolare:742.29893ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Formula:C17H13Cl2N3O4SPurezza:99.87%Colore e forma:SolidPeso molecolare:426.27Ref: TM-T64320
1mg109,00€5mg260,00€1mL*10mM (DMSO)285,00€10mg409,00€25mg677,00€50mg954,00€100mg1.288,00€200mg1.728,00€Antitrypanosomal agent 12
Antitrypanosomal agent 12, a C20-phenylthiourea, exhibits trypanocidal and cytotoxic activities, demonstrating antitrypanosomal activity with GI50 values of 0.Formula:C49H77N2NaO10SPurezza:98%Colore e forma:SolidPeso molecolare:909.2Antimalarial agent 31
Compound 31 (compound 7k) is an orally active inhibitor of Plasmodium falciparum aspartic protease, plasmepsin X (PMX), with antimalarial properties [1].Formula:C36H47N3O4Purezza:98%Colore e forma:SolidPeso molecolare:585.78Antimalarial agent 28
Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P.
Formula:C27H25ClFN3O2Purezza:98%Colore e forma:SolidPeso molecolare:477.96Sarolaner
CAS:Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).Formula:C23H18Cl2F4N2O5SPurezza:99.54% - 99.65%Colore e forma:SolidPeso molecolare:581.36Cysteine protease inhibitor-3
Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM),Formula:C26H22ClF2N3OPurezza:98%Colore e forma:SolidPeso molecolare:465.924-(Trifluoromethyl)nicotinic acid
CAS:Compound FL0181, with CAS No. 158063-66-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0181 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C7H4F3NO2Purezza:98%Peso molecolare:191.11Antiparasitic agent-26
Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).
Colore e forma:Odour SolidUrethane
CAS:Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.Formula:C3H7NO2Purezza:99.01%Colore e forma:SoildPeso molecolare:89.09Ile-AMS TFA
Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.Formula:C18H27F3N8O8SColore e forma:SolidPeso molecolare:572.52Antitrypanosomal agent 23
Antitrypanosomal agent 23 is an antiparasitic compound effective against intracellular amastigotes of Trypanosoma cruzi in LLC-MK2 and C2C12 cells, demonstrating activity with IC50 values of 0.10 and 0.11 μM, respectively. It also acts as a weak inhibitor of recombinant Trypanosoma cruzi sialyltransferase (TcTS) with an IC50 of 1.1 mM.Formula:C14H16N4O7Colore e forma:SolidPeso molecolare:352.1019Antileishmanial agent-20
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L.Formula:C15H16N4O3Purezza:98%Colore e forma:SolidPeso molecolare:300.31Antitrypanosomal agent 17
Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1].Purezza:98%Colore e forma:Odour SolidNorselic acid B
CAS:Norselic acid B is a naturally occurring compound that can be isolated from the sponge Crella sp. collected in Antarctica. It demonstrates activity against Leishmania parasites.Formula:C29H44O4Colore e forma:SolidPeso molecolare:456.657β-Hederin
CAS:β-Hederin has antileishmanial activity. β-Hederin has apoptotic effect on cancer cells, it could be a promising candidate for chemotherapy of breast cancer.Formula:C41H66O11Purezza:98%Colore e forma:SolidPeso molecolare:734.96Azlocillin sodium salt
CAS:Azlocillin sodium, an acylampicillin, is a broad-spectrum antibioticsFormula:C20H22N5NaO6SPurezza:97.63% - 98.302%Colore e forma:SolidPeso molecolare:483.47Antimalarial agent 27
Antimalarial agent 27 (compound 11a) potently inhibits P.Formula:C10H11NNaO5PPurezza:98%Colore e forma:SolidPeso molecolare:279.16ACT-451840
CAS:ACT-451840 eliminates both sensitive and resistant strains of Plasmodium falciparum and has the advantages of oral, potency, low toxicity, rapid.Formula:C47H54N6O3Purezza:96.07%Colore e forma:SolidPeso molecolare:750.97Ref: TM-T203012
1mg108,00€5mg229,00€1mL*10mM (DMSO)239,00€10mg366,00€25mg701,00€50mg1.123,00€100mg1.700,00€Antiproliferative agent-56
Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.Colore e forma:Odour SolidAAP4
AAP4 is a potent inhibitor of OfChi-h and OfHex1, exhibiting Ki values of 29.3 nM and 4.9 μM, respectively. It also demonstrates insecticidal activity against the lepidopteran pest Ostrinia furnacalis.Formula:C21H23BrClN7Colore e forma:SolidPeso molecolare:488.8118304-vs
8304-vs is a macrocyclic anti-Plasmodial compound that irreversibly binds to and inhibits the Plasmodium proteasome, effectively halting the growth ofFormula:C35H53N5O8SPurezza:98%Colore e forma:SolidPeso molecolare:703.89CpNMT-IN-1
CpNMT-IN-1 (Compound 11e) is an inhibitor of N-myristoyltransferase (CpNMT) with an IC50 value of 2.5 μM. It also inhibits the growth of microsporidia, demonstrating an EC50 value of 6.9 μM.Formula:C25H25ClN4O4SColore e forma:SolidPeso molecolare:513.008LASSBio-1985
LASSBio-1985 is an inhibitor of NHLd (nucleoside hydrolase of Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. It exhibits selective toxicity against Leishmania parasites without affecting mammals, showing potential for research in infectious disease treatment.Formula:C18H22N2O7Colore e forma:SolidPeso molecolare:378.38Antimalarial agent 43
Antimalarial agent 43 (compound 16c) is an antimalarial compound that exhibits an IC50 value of 0.0151 μM against the 3D7 strain.Colore e forma:Odour SolidEmoquine-1
Emoquine-1 is a potent orally active antimalarial agent effective against various drug-resistant Plasmodium strains, including artemisinin-resistant dormant parasites. It demonstrates efficacy against proliferative malignant Plasmodium with an IC50 value ranging from 20 to 55 nM. Emoquine-1 holds potential for treating Plasmodium strains resistant to artemisinin combination therapy (ACT), with the capability to eradicate persistent parasites.Formula:C30H28ClN3O6Colore e forma:SolidPeso molecolare:562.013Febrifugine dihydrochloride
CAS:Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatoryFormula:C16H21Cl2N3O3Purezza:98.27% - 99.85%Colore e forma:SolidPeso molecolare:374.26Ref: TM-TN1012L
25mgPrezzo su richiesta50mgPrezzo su richiesta1mg50,00€2mg71,00€5mg105,00€10mg167,00€Antimalarial agent 47
Antimalarial agent 47 (compound F14) is a chemical compound effective against Plasmodium falciparum, specifically targeting the W2 strain with an IC50 value of 235 nM.Formula:C16H14ClF2NOColore e forma:SolidPeso molecolare:309.74Nitroxynil
CAS:Nitroxynil is an anthelmintic for adult/immature parasites, mainly used in Fasciola hepatica studies.Formula:C7H3IN2O3Purezza:99.76%Colore e forma:SolidPeso molecolare:290.01Antileishmanial agent-24
Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM againstFormula:C34H29Cl4N3O2Purezza:98%Colore e forma:SolidPeso molecolare:653.42Amprolium
CAS:Amprolium is a veterinary coccidiostat that interferes with THIAMINE metabolism.Formula:C14H19N4·ClPurezza:98%Colore e forma:SolidPeso molecolare:278.79Anti-Trypanosoma cruzi agent-6
Anti-Trypanosoma cruzi agent-6 (Compound 8) exhibits inhibitory activity against Trypanosoma cruzi. It effectively suppresses the epimastigote, trypomastigote, and amastigote forms of T. cruzi, with IC50 values of 24.7 µM, 1.8 µM, and 1.6 µM, respectively.Formula:C19H20N2O5Colore e forma:SolidPeso molecolare:356.37SpdSyn binder-1
CAS:SpdSyn binder-1 weakly inhibits malaria by binding to Plasmodium falciparum's spermidine synthase. Used for research.Formula:C21H22N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:346.43Antileishmanial agent-26
Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with activity against *Leishmania donovani*, exhibiting an IC50 value of 5.67 μM and a CC50 value of 3.79 μM in THP-1 cells. This compound is applicable for research in tropical diseases.Formula:C23H27FN4O2Peso molecolare:410.2118CpCDPK1/TgCDPK1-IN-2
CAS:CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can
Formula:C20H21N5OPurezza:99.12%Colore e forma:SoildPeso molecolare:347.41Dixanthogen
CAS:Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.Formula:C6H10O2S4Purezza:95% - 98%Colore e forma:SolidPeso molecolare:242.4Se2h
Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55). Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.Formula:C12H13ClN4O2SeColore e forma:SolidPeso molecolare:359.67Alkaline tryptase-IN-1
Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.Formula:C29H33BrN2O2SColore e forma:SolidPeso molecolare:553.554-(2-Aminoethyl)amino-7-chloroquinoline
CAS:4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) has potential anthelmintic and antitumor activity for the study ofFormula:C11H12ClN3Purezza:98.53%Colore e forma:SolidPeso molecolare:221.69Antileishmanial agent-25
Antileishmanial agent-25 (compound 24) exhibits selective activity against intracellular amastigotes, demonstrating an inhibitory concentration (IC50) of 6.63Purezza:98%Colore e forma:Odour SolidAntileishmanial agent-19
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L.Formula:C22H18N4O3Purezza:98%Colore e forma:SolidPeso molecolare:386.4Antileishmanial agent-31
CAS:Antileishmanial agent-31 (Compound p1) is a pyrazole derivative exhibiting antileishmanial activity with an IC50 of 35.53 μg/mL. Furthermore, Antileishmanial agent-31 demonstrates high stability and is applicable in studies focused on leishmaniasis treatment.Formula:C11H11ClN2Colore e forma:SolidPeso molecolare:206.67
