Antiparassitari
Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.
Trovati 704 prodotti di "Antiparassitari"
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CpCDPK1/TgCDPK1-IN-2
CAS:<p>CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can</p>Formula:C20H21N5OPurezza:99.12%Colore e forma:SoildPeso molecolare:347.41PfSUB1-IN-1
<p>PfSUB1-IN-1 (compound 4c) is an inhibitor of Plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1), exhibiting potent activity with an IC50 value of 15 nM. PfSUB1 is a key target in antimalarial research. PfSUB1-IN-1 demonstrates a 13-fold greater inhibitory effect on the growth of transgenic Plasmodium falciparum strains (expressing lower levels of PfSUB1 compared to the wild-type) than on wild-type parasite strains.</p>Colore e forma:Odour SolidAntileishmanial agent-30
<p>Compound 17k, also known as Antileishmanial agent-30, effectively inhibits Leishmania with an IC50 of 0.2 μM for L. donovani. It exhibits a CC50 of >100 μM and an SI of >500, indicating significant selectivity and potency.</p>Formula:C23H21N5O2Colore e forma:SolidPeso molecolare:399.453-Deoxyaphidicolin
CAS:<p>3-Deoxyaphidicolin is a phytotoxin that inhibits root growth in lettuce seedlings. Additionally, 3-Deoxyaphidicolin exhibits inhibitory activity against the protozoan parasites Leishmania major and Leishmania braziliensis.</p>Formula:C20H34O3Colore e forma:SolidPeso molecolare:322.48Amitraz
CAS:<p>Amitraz (NSC 324552): white monoclinic crystals, mp 86-87°C, water-insoluble, used as acaricide and in canine demodectic mange.</p>Formula:C19H23N3Purezza:99.88%Colore e forma:White/Pale Yellow Crystalline SolidPeso molecolare:293.41Dodecamethylpentasiloxane
CAS:<p>Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.</p>Formula:C12H36O4Si5Purezza:97.43%Colore e forma:SolidPeso molecolare:384.84LL-37 FK-13 TFA
<p>LL-37 FK-13 TFA, the TFA salt form of LL-37 FK-13, is an antimicrobial agent that inhibits Trichomonas vaginalis. It exhibits minimal hemolytic effects on human red blood cells and shows slight cytotoxicity towards human fibroblasts.</p>Colore e forma:Odour SolidMMV1634566
<p>MMV1634566 is an effective antimalarial agent that can inhibit Plasmodium falciparum and exhibits cytotoxicity.</p>Colore e forma:Odour SolidAntimalarial agent 42
<p>Compound 42 (Compound 2), an antimalarial agent, effectively inhibits Plasmodium falciparum during the asexual blood stages (IC 50 <0.5μM) and gametocytes (IC 50 is 0.14 μM).</p>Formula:C24H42N2Colore e forma:SolidPeso molecolare:358.6AChE-IN-66
<p>Nematicidal Agent 1 is an effective nematicide that binds to the pocket of acetylcholinesterase (AChE).</p>Colore e forma:Odour SolidBitoscanate
CAS:<p>Bitoscanate (PDITC) is used in the treatment of hookworms.</p>Formula:C8H4N2S2Purezza:98.32%Colore e forma:Colorless Needles Bitoscanate Is An Odorless Colorless Crystals Melting Point 132°CPeso molecolare:192.26SpdSyn binder-1
CAS:<p>SpdSyn binder-1 weakly inhibits malaria by binding to Plasmodium falciparum's spermidine synthase. Used for research.</p>Formula:C21H22N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:346.43Se2h
<p>Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55). Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.</p>Formula:C12H13ClN4O2SeColore e forma:SolidPeso molecolare:359.67JC-229
CAS:<p>JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).</p>Formula:C20H14Cl4N2O3SPurezza:97.14%Colore e forma:SolidPeso molecolare:504.21Insecticidal agent 24
<p>Insecticidal agent 24 is an orally active pyridinyl spiroindoline lead compound. It demonstrates antimalarial activity with Pf NF54IC50 of 0.08 μM. Insecticidal agent 24 also inhibits hERG activity with an IC50 of 6.5 μM. In a humanized immunodeficient NSG mouse model of malaria infection, it effectively reduces parasitemia.</p>Formula:C26H29N3O2Colore e forma:SolidPeso molecolare:415.22598pCDPK1/TgCDPK1-IN-3
CAS:<p>CpCDPK1/TgCDPK1-IN-3 inhibits Cp/TgCDPK1; IC50: 0.003/0.0036 µM. It's used to research Toxoplasma, Cryptosporidium diseases.</p>Formula:C17H18N6Purezza:99.63%Colore e forma:SoildPeso molecolare:306.36ML251
CAS:<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Formula:C17H13Cl2N3O4SPurezza:99.87%Colore e forma:SolidPeso molecolare:426.271,2-Dimethyl-1H-benzo[d]imidazole
CAS:<p>1,2-Dimethyl-1H-benzo[d]imidazole has antibacterial activity against Entamoeba histolytica and Giardia lamblia,</p>Formula:C9H10N2Purezza:99.86%Colore e forma:SolidPeso molecolare:146.19Antimalarial agent 13
CAS:<p>Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) is a potent antimalarial agent.</p>Formula:C19H15ClN4OPurezza:99.15%Colore e forma:SolidPeso molecolare:350.8N-Methyl-1,3-benzoxazol-2-amine
CAS:<p>N-Methyl-1,3-benzoxazol-2-amine, with CAS No. 19776-98-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-Methyl-1,3-benzoxazol-2-amine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C8H8N2OColore e forma:SoildPeso molecolare:148.1616Eflornithine
CAS:<p>Eflornithine blocks ornithine decarboxylase, treating African trypanosomiasis and female facial hair.</p>Formula:C6H12F2N2O2Purezza:99.44% - 99.84%Colore e forma:SolidPeso molecolare:182.17Antileishmanial agent-33
<p>Antileishmanial agent-33 (4e) is a hybrid compound of grandisin and machilin G, demonstrating moderate activity against promastigotes with an IC50 of 38.1 μM. In studies of cutaneous leishmaniasis (CL), Antileishmanial agent-33 (4e) has shown potential as an antileishmanial agent.</p>Colore e forma:Odour SolidACT-451840
CAS:<p>ACT-451840 eliminates both sensitive and resistant strains of Plasmodium falciparum and has the advantages of oral, potency, low toxicity, rapid.</p>Formula:C47H54N6O3Purezza:96.07%Colore e forma:SolidPeso molecolare:750.97Biotin-PEG3-Mal
CAS:<p>Biotin-PEG3-Mal (Biotin-PEG3-NH-Mal) is a biotin-labeled PROTAC linker belonging to the PEG class that can be used to synthesize PROTAC molecules.</p>Formula:C25H39N5O8SPurezza:99.5%Colore e forma:SolidPeso molecolare:569.67Proteasome-IN-6
<p>Proteasome-IN-6 (Compound J-80) inhibits the β5 catalytic subunit of the Trypanosoma brucei 20S proteasome, effectively blocking T. b. brucei, T. b. gambiense, and T. b. rhodesiense with EC50 values of 157 nM, 220 nM, and 156 nM, respectively. Additionally, Proteasome-IN-6 has demonstrated antitrypanosomal activity in a mouse model.</p>Formula:C35H45F3N4O6Colore e forma:SolidPeso molecolare:674.75Pyronaridine tetraphosphate
CAS:<p>Pyronaridine tetraphosphate is a DNA topoisomerase 2 inhibitor with antimalarial and antitumor activity for the treatment of P. falciparum infection.</p>Formula:C29H44ClN5O18P4Purezza:99.82%Colore e forma:SolidPeso molecolare:910.03Nanaomycin A
CAS:<p>Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).</p>Formula:C16H14O6Purezza:98%Colore e forma:SolidPeso molecolare:302.28WJM280
<p>WJM280 is an orally active antimalarial compound with an EC50 of 0.04 μM against the parasite P. falciparum 3D7.</p>Formula:C22H25F3N2OColore e forma:SolidPeso molecolare:390.44Antimalarial agent 45
<p>Antimalarial agent 45 (compound 8I) is an antimalarial with activity against Plasmodium parasites, exhibiting an IC50 of 0.21 μM. It is used in the study of malaria.</p>Formula:C33H34N4O3Colore e forma:SolidPeso molecolare:534.65Mepartricin
CAS:<p>Mepartricin, a polyene macrolide, exhibits both antifungal and antiprotozoal activities and is extensively utilized in studies related to benign prostatic hyperplasia.</p>Colore e forma:SolidSchizophyllan
CAS:<p>Schizophyllan, a member of the β-glucan family, is an extracellular polysaccharide known for its antitumor, antibacterial, and antiparasitic activities.</p>Colore e forma:SolidIle-AMS TFA
<p>Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.</p>Formula:C18H27F3N8O8SColore e forma:SolidPeso molecolare:572.52Cinchonidine
CAS:<p>Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.</p>Formula:C19H22N2OPurezza:94.96% - 99.87%Colore e forma:White PowderPeso molecolare:294.39Gypsogenic acid
CAS:<p>Gypsogenic acid, a triterpenic acid isolated from Miconia stenostachya, exhibits antibacterial and antitrypanosomal activities. This compound demonstrates minimum inhibitory concentrations (MICs) ranging from 50-200 μg/mL against oral bacterial pathogens including Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus spp., and Streptococcus sobrinus. Additionally, gypsogenic acid can induce the lysis of Trypanosoma cruzi in isolated mouse blood, with an IC50 value of 56.6 μM.</p>Formula:C30H46O5Colore e forma:SolidPeso molecolare:486.68Cletoquine
CAS:<p>Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.</p>Formula:C16H22ClN3OPurezza:99.95% - 99.98%Colore e forma:SolidPeso molecolare:307.82Antitrypanosomal agent 15
<p>Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4</p>Formula:C21H19FN4O4Purezza:98%Colore e forma:SolidPeso molecolare:410.4Human α-defensin 5
<p>Human α-defensin 5 is an antiviral peptide that inhibits the infection of non-enveloped viruses such as AdV, HPV, and polyomaviruses, with an IC50 range of 0.6-</p>Formula:C144H238N50O45S6Purezza:98%Colore e forma:SolidPeso molecolare:3582.13Urethane
CAS:<p>Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.</p>Formula:C3H7NO2Purezza:99.01%Colore e forma:SoildPeso molecolare:89.09Antiparasitic agent-25
<p>Antiparasitic agent-25 (Compounds 11) is an orally active antiparasitic compound. It inhibits the invasion and replication capabilities of parasites and has an irreversible effect on Toxoplasma gondii. The agent significantly reduces the replication rate of Toxoplasma gondii, with an IC50 value of 6.33 μM, and exhibits low cytotoxicity, having a CC50 value of 285 μM.</p>Colore e forma:Odour SolidFebrifugine dihydrochloride
CAS:<p>Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory</p>Formula:C16H21Cl2N3O3Purezza:98.27% - 99.85%Colore e forma:SolidPeso molecolare:374.264-Propylbenzene-1,2-diol
CAS:<p>4-Propylbenzene-1,2-diol exhibits antimalarial activity and can inhibit Plasmodium falciparum,</p>Formula:C9H12O2Purezza:98.84%Colore e forma:SolidPeso molecolare:152.19Modoflaner
CAS:<p>Modoflaner is an antiparasitic (veterinary use).</p>Formula:C23H10F12IN3O2Purezza:98.78%Colore e forma:SolidPeso molecolare:715.23Antimalarial agent 49
<p>Antimalarial agent 49 is an oral compound with antimalarial properties. It inhibits the growth of Pf3D7 and PfK1 strains, with IC50 values of 0.84 μM and 0.4 μM, respectively. Additionally, it demonstrates the ability to suppress the liver stage development of P. berghei and can be utilized in malaria infection research.</p>Colore e forma:Odour SolidAntiparasitic agent-24
<p>Antiparasitic agent-24 (Compound 14a) is an antiparasitic compound with EC50 values of 0.005 μM for L. maj, 0.069 μM for L. don, 0.82 μM for T. brucei, and 4.1 μM for T. cruzi.</p>Formula:C23H22ClN7O2SColore e forma:SolidPeso molecolare:495.98CCOE-5
<p>CCOE-5 is a chalcone derivative with antimalarial activity, exhibiting an IC50 of 1.4 μg/mL against P. falciparum (3D7) and an IC50 of less than 5 μg/mL against P. falciparum (INDO). CCOE-5 shows potential for research in the anti-infective domain.</p>Formula:C34H31NO6Colore e forma:SolidPeso molecolare:549.61Sarolaner
CAS:<p>Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).</p>Formula:C23H18Cl2F4N2O5SPurezza:99.54% - 99.65%Colore e forma:SolidPeso molecolare:581.36Dixanthogen
CAS:<p>Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.</p>Formula:C6H10O2S4Purezza:95% - 98%Colore e forma:SolidPeso molecolare:242.4Azlocillin sodium salt
CAS:<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>Formula:C20H22N5NaO6SPurezza:97.63% - 98.302%Colore e forma:SolidPeso molecolare:483.47Arprinocid
CAS:Formula:C12H9ClFN5Purezza:>95.0%(HPLC)Colore e forma:White to Yellow to Orange powder to crystalPeso molecolare:277.69Albendazole Sulfoxide
CAS:Formula:C12H15N3O3SPurezza:>98.0%(N)Colore e forma:White to Light yellow powder to crystalPeso molecolare:281.33
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