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Antiparassitari

Antiparassitari

Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.

Trovati 701 prodotti di "Antiparassitari"

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  • NEU-1017

    CAS:
    NEU-1017 serves as a broad-spectrum antiparasitic compound, effectively inhibiting T. brucei, L. major, and P. falciparum with EC50 values of 210 nM, 240 nM, and 3 nM, respectively.
    Formula:C33H31ClFN5O3S
    Colore e forma:Solid
    Peso molecolare:632.147
  • MMV03

    CAS:
    <p>MMV03 is an antimalarial compound effective against Plasmodium falciparum, with an EC50 of 0.6 μM.</p>
    Formula:C19H14N4OS
    Colore e forma:Solid
    Peso molecolare:346.406
  • WR-27653

    CAS:
    WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.
    Formula:C20H36BrN3O2
    Colore e forma:Solid
    Peso molecolare:430.423
  • SLU-10906

    CAS:
    SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.
    Formula:C22H21BFN5O2
    Colore e forma:Solid
    Peso molecolare:417.244
  • MED6-189

    CAS:
    MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.
    Formula:C17H26N2O
    Colore e forma:Solid
    Peso molecolare:274.40
  • Ferrocene

    CAS:
    Ferrocene, a crucial structural core in bioorganometallic chemistry, is renowned for its intrinsic stability, excellent oxygen reduction capabilities, and low toxicity. It also exhibits antimalarial and anticancer properties.
    Formula:C10H10Fe
    Colore e forma:Solid
    Peso molecolare:186.03
  • LN002

    CAS:
    LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.
    Formula:C22H15N7
    Colore e forma:Solid
    Peso molecolare:377.40
  • Ipronidazole

    CAS:
    Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.
    Formula:C7H11N3O2
    Colore e forma:Solid
    Peso molecolare:169.18
  • Arohynapene B

    CAS:
    Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.
    Formula:C18H22O3
    Colore e forma:Solid
    Peso molecolare:286.366
  • Insecticidal agent 16

    CAS:
    Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.
    Formula:C21H13Cl2F6N5O2S
    Colore e forma:Solid
    Peso molecolare:584.32
  • PIQ-2

    CAS:
    PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.
    Formula:C23H21F3N4O3
    Colore e forma:Solid
    Peso molecolare:458.43
  • Antimalarial agent 48

    CAS:
    <p>Antimalarial agent 48 (Compound 15a) is a triazine compound with antimalarial activity, showing effectiveness against Plasmodium falciparum K1 and Plasmodium falciparum FCR3 with IC50 values of 280 and 290 nM, respectively. It holds promise for research in the field of anti-infective treatments.</p>
    Formula:C19H14F3N11
    Colore e forma:Solid
    Peso molecolare:453.383
  • Menoctone

    CAS:
    Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.
    Formula:C24H32O3
    Colore e forma:Solid
    Peso molecolare:368.51
  • Etofamide

    CAS:
    Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.
    Formula:C19H20Cl2N2O5
    Colore e forma:Solid
    Peso molecolare:427.28
  • Noracronycine

    CAS:
    Noracronycine is an alkaloid originally isolated from G. pentaphylla, known for its antimalarial activity. It is effective against P. yoelii at a concentration of 10 μg/mL.
    Formula:C19H17NO3
    Peso molecolare:307.34
  • SAL-0010042

    CAS:
    SAL-0010042 is an inhibitor of Plasmodium phosphodiesterase β (PDEβ), effectively blocking the hydrolysis of cAMP and cGMP in gametocytes with an IC50 of 48.9 nM, thereby activating PKG and inhibiting the growth and development of Plasmodium (IC50s for 3D7 and Dd2 are 142 nM and 218 nM, respectively). It also inhibits hPDE5 and hPDE6 with IC50 values of 632 nM and 73 nM, respectively.
    Formula:C15H15FN4O
    Colore e forma:Solid
    Peso molecolare:286.304
  • SPB07935

    CAS:
    SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.
    Formula:C22H15N5O4S2
    Colore e forma:Solid
    Peso molecolare:477.516
  • Erythromycin B

    CAS:
    <p>Erythromycin B exhibits antimalarial activity by effectively inhibiting the asexual growth of Plasmodium falciparum.</p>
    Formula:C37H67NO12
    Colore e forma:Solid
    Peso molecolare:717.93
  • PFK-IN-1

    CAS:
    <p>PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.</p>
    Formula:C18H15Cl2N3O4S
    Colore e forma:Solid
    Peso molecolare:440.3
  • 2-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-

    CAS:
    Formula:C27H22Cl2N4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:473.3964

    Ref: IN-DA00I3TE

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