Zuccheri e nucleobasi della spina dorsale

Applications 6-​Methyl-​2-​thiouracil is a derivative of methylthiouracil (M330710), a competitive inhibitor of Nitric Oxide Synthase (NOS). Potential anti-inflammatory agent.
References Palumbo, A. et al.: Biochem. Bioph. Res. Co. 282, 793(2001), Ku, S. et al.: Toxicol. App. Pharmacol., 288, 374 (2015);

Applications Nucleoside derivatives of 5-substituted uracil have been explored for their potential application as anti-viral agents and in the treatment of tumors.
References Ressner, E.C., et al.: J. Med. Chem., 19, 1, 194 (1976)

Applications 6-​Phenyl-​2-​thiouracil is a reagent used in the synthesis of antifungal agents.
References Gullapelli, K. et al.: Int. J. Pharm. Biol. Sci., 4, 59 (2014);

Applications 6-Amino-5-1,3-dimethyl-5-(formamido)uracil is a substitued uracilic metabolite of methylxanthine and is also a metabolite of Theophylline (T343850). 6-Amino-5-1,3-dimethyl-5-(formamido)uracil has been used for the synthesis of 8-arylaminotheophyllines.
References Peri, G., et. al.: Toxicol. Lett., 18, 133 (1983); Celardo, A., et. al.: Eur. J. Drug Metab. Ph., 10, 279 (1985); Senga, K., et. al.: J. Heterocyclic Chem., 15, 641 (1978)

Applications 1,3-Diethyl-6-aminouracil (cas# 41740-15-2) is a compound useful in organic synthesis.

Applications 8-Benzyloxy-2’-deoxyguanosine (cas# 96964-90-8) is a compound useful in organic synthesis.
References Wang, Y., et al.: Chem. Res. Toxicol., 19, 837 (2006),

Applications 2'-Deoxy-N3-methyluridine (cas# 24514-32-7) is a useful research chemical.

Applications Guanidinoacetic Acid is an important marker for renal failure, in kidney transplantation, and for the renal metabolic activity.
References Zugno, A., et al.: Neurochem. Res., 33, 1804 (2008), Debray, F., et al.: Neurol., 71, 44 (2008), da Silva, R., et al.: Am. J. Physiol., 296, E256 (2009),

Applications Protected guanine
References Tretyakova, N., et al.: Chem. Res. Toxicol., 20, 284 (2007), Rana, S., et al.: Bioorg. Med. Chem. Lett., 19, 670 (2009),

Applications 5,6-Dimethylthiouracil is a heterocyclic building block.

Stability Hygroscopic
Applications 5-Hydroxymethyl-2’-deoxyuridine acts as a biomarker for the diagnosis for oxidative stress in humans. Used as a diagnostic to for propensitiy for the development of breast cancer.
References McAnulty, L. et al.: App. Physiol. Nutr. Metab., 36, 976 (2011); Djuric Z. et al.: Cancer Epidemiol. Biomarkers. Prev., 10, 147 (2001); Frenkel, K. et al.: 7, 49, (1998);

Applications 5-Hydroxymethyluracil (cas# 4433-40-3) is a compound useful in organic synthesis.

Stability Stable at RT
Applications An intermediate used for the sythesis of xanthine derivatives.
References Daly, J.W., et al.: J. Med. Chem., 28, 487 (1985), Erickson, R.H., et al.: J. Med. Chem., 34, 3405 (1991),

Applications 5,6-Dihydrothymine is a derivative of Thymine, a nucleobase in the nucleic acid of DNA . 5,6-Dihydrothymine is a radiolysis product of DNA.
References Hubbard, K. et al.: Biochemistry, 28, 4382 (1989); Cadet, J. et al.: Int. J. Rad. Biol. Rel. Stud. Phys. Chem. Med., 39, 119 (1981);