Lipidi

<p>Applications Propacetamol HCl (cas# 66532-86-3) is a useful research chemical.<br></p>

<p>Applications Cholesterol (C432501) derivative. Cholesterol is a major component of all biological membranes; ~25% of total brain lipid is Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 1,2-Dilinoleoyl-3-oleoyl-rac-glycerol is a triacylglycerol found in sesame oil.<br>References Lee, D., et al.: Analytica Chimica Acta, 429, 321 (2001); Jahaniaval, F., et al.: J. AM. Oil Chem. Soc., 77,847 (2000)<br></p>

<p>Applications Tetrahydro 11-Deoxycorticosterone is a metabolite of 11-Deoxycorticosterone (DOC) (D232590).<br>References Fedele, E., et al.: J. Neurochem., 75, 782 (2000), Adkins, C., et al.: J. Biol. Chem., 276, 38934 (2001), Erceg, S., et al.: Brain Res., 1036, 115 (2005),<br></p>

<p>Applications 20-HETE is a cytochrome P450 (CYP450) metabolite that may play an autacoid role in cerebral and renal vasculature.<br>References McGiff, J.C., et al.: Am J Physiol, 277, R607-R623 (1999);<br></p>

<p>Impurity Estradiol 17?-Hydroxy Impurity; Estradiol EP Impurity B; Ethinylestradiol EP Impurity L<br>Applications Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain(1,2). 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke(3).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Lievertz, R. et al.: J. Obstet. Gynecol. 1987 May;156(5):1289-932. Kuhnz, W. et al.: Arzneimittelforschung. 1993 Sep;43(9):966-73.3. Toran-Allerand, C. et al.: Endocrinology. 2005 Sep;146(9):3843-50.<br></p>

<p>Applications Glycidyl Myristate is formed from monoacylglycerols and are present in edible fats and oils.<br>References Zuzana, Z et al.: 77, 65 (2017);<br></p>

<p>Applications A metabolite of Cholesterol. Its membrane organizing properties could have implications in Altzheimer’s disease.<br>References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007); S.L. Regen et al.: J. Amer. Chem. Soc., 131, 12354 (2009)<br></p>

<p>Applications Aglicone of saponin dioscin. Diosgenin exists in some food supplements and herbal medicines and lowers plasma cholesterol by increasing fecal cholesterol excretion. It can be converted to Pregnenolone and Progesterone.<br>References Cayen, M., et al.: J. Lipid Res., 20, 162 (1979), Nervi, F., et al.: J. Clin. Invest., 74, 2226 (1984), Davis, H., et al.: J. Biol. Chem., 279, 33586 (2004), Brown, J., et al.: Biochem. J., 406, 273 (2007),<br></p>

<p>Applications C20 Dihydroceramide (cas# 121459-06-1) is a compound useful in organic synthesis.<br></p>

<p>Applications Food preservative, having the ability to form complexes with starch, retarding its retrodegradation during storage.<br>References Yu, S., et al.: J. Agric. Food Chem., 54, 4482 (2006),<br></p>

<p>Stability Hygroscopic<br>Applications 20(S)-Ginsenoside Rg2 is used as an aldose reductase inhibitor and my exert anti-inflammatory and immunomodulatory activity. It exists as a bioactive metabolite of the ginsenoside component of Panax ginseng.<br>References Cho, K. et al.: Biomol. Ther., 22, 55 (2014); Fatmawati, S. et al.: Bioorg. Med. Chem. Lett., 24, 4407 (2014);<br></p>

<p>Applications FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-phosphate.<br>References Chiba, K., et al.: J. Immunol., 160, 5037 (1998), Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002), Kiuchi, M., et al.: Bioorganic &amp; Medicinal Chemistry, 13, 425 (2005<br></p>

<p>Applications Campesterol is a phytosterol that may inhibit the intestinal absorption of cholesterol.<br>References Fransen, H., et al.: J. Nut., 140, 1062 (2010), Kojoma, M., et al.: Plant Biotechnol., 27, 59 (2010), Orozco-Solano, M., et al.: J. Agric. Food Chem., 58, 7539 (2010),<br></p>