Nucleotidi
I nucleotidi sono composti organici che fungono da mattoni per la costruzione degli acidi nucleici, essenziali per la formazione del DNA e dell'RNA. Ogni nucleotide è composto da una base azotata, una molecola di zucchero e uno o più gruppi fosfato. Questi nucleotidi si uniscono per formare lunghe catene, creando il materiale genetico che porta e trasmette informazioni genetiche in tutti gli organismi viventi. In questa sezione, troverai una vasta gamma di nucleotidi cruciali per la ricerca in genetica, biologia molecolare e biochimica. Sono fondamentali per studiare i processi genetici, sintetizzare acidi nucleici e sviluppare strumenti diagnostici e terapeutici. Da CymitQuimica, offriamo nucleotidi di alta qualità per supportare la tua ricerca scientifica e applicazioni, garantendo precisione e affidabilità nei tuoi esperimenti.
Sottocategorie di "Nucleotidi"
Trovati 2634 prodotti di "Nucleotidi"
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2',3'-O-Isopropylideneadenosine
CAS:<p>2',3'-O-Isopropylideneadenosine is a nucleoside that has a possible usage as an organic chemical synthesis intermediate</p>Formula:C13H17N5O4Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:307.31 g/molThymidine
CAS:<p>Thymidine, also known as deoxythymidine (dT), is a pyrimidine deoxynucleoside that pairs with deoxyadenosine (dA) in a double stranded DNA. It’s used as a biochemical modulator of antimetabolites such as 5-fluorouracil (5-FU), 1-beta-D-arabinofuranosylcytosine (Cytarabine) and methotrexate (MTX) in cancer therapy. It’s also the enantiomer of telbivudine, an antiviral drug used to treat hepatitis B virus (HBV) infection.</p>Formula:C10H14N2O5Purezza:Min. 99.0 Area-%Colore e forma:White PowderPeso molecolare:242.23 g/molGlycinamide ribonucleotide
CAS:<p>Glycinamide ribonucleotide (GAR) is a reactive metabolite that is formed from glycinamide, which is an intermediate in the synthesis of purines. GAR has been shown to bind to intracellular targets and inhibit their enzyme activities. GAR has been shown to inhibit the activity of enzymes that are involved in the synthesis of purines, such as ribonucleotides and nucleoside phosphates. These enzymes have been found in human tissues. GAR also inhibits the polymerase chain reaction (PCR) by binding to DNA and inhibiting its replication. This drug has also been shown to be effective against bowel disease by binding to bacterial dna gyrase, dna topoisomerase, and rna synthesis.</p>Formula:C7H15N2O8PPurezza:Min. 80 Area-%Colore e forma:PowderPeso molecolare:286.18 g/molRef: 3D-NG59700
Prodotto fuori produzione1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil
CAS:<p>1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil is a modified nucleoside analog with structural alterations that enhance its biological properties and stability. The compound features 5-fluorouracil as the nucleobase, a fluorinated pyrimidine often used in chemotherapy due to its ability to interfere with DNA replication. The sugar component is 2,3-dideoxy-β-L-glycero-pent-2-enofuranose and has a specific glycerol and enol configuration, which alters its interactions with enzymes involved in nucleic acid metabolism. The compound includes a 5-O-acetyl protecting group at the 5'-position, which shields the hydroxyl group during synthesis.</p>Formula:C11H11FN2O5Purezza:Min. 95%Peso molecolare:270.21 g/molRef: 3D-NA182971
Prodotto fuori produzioneCytidyl-3'-5'-uridine ammonium
CAS:<p>Cytidyl-3'-5'-uridine ammonium salt is a nucleoside analog that is used as an antiviral and anticancer agent. Cytidyl-3'-5'-uridine ammonium salt inhibits the synthesis of DNA by inhibiting the activity of enzymes such as DNA polymerase, RNA polymerase, or reverse transcriptase. It also has antitumor properties and can be used to treat leukemia and other types of cancer. Cytidyl-3'-5'-uridine ammonium salt has been shown to be more potent than cytidyl-2',4',6'-triaminopyrimidine (CTAP) in inhibiting the growth of lymphocytic leukemia cells.</p>Formula:C18H24N5O13P•NH3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:566.42 g/molRef: 3D-NC07990
Prodotto fuori produzioneCladribine
CAS:<p>Deoxyadenosine analog resistant to adenosine deaminase</p>Formula:C10H12ClN5O3Purezza:Min. 97 Area-%Colore e forma:PowderPeso molecolare:285.69 g/mol5'-O-DMT-2'-O-methylcytidine
CAS:<p>5'-O-DMT-2'-O-methylcytidine is a monophosphate nucleoside of cytidine. It is used as an antiviral agent and has been shown to have anticancer effects in vitro. 5'-O-DMT-2'-O-methylcytidine is synthesized by modification of the natural deoxyribonucleosides, which are then phosphoramidited to form a 5'-O-DMT-2'-O-methylcytidine monophosphate. The synthesis process also produces diphosphate and triphosphate forms of the nucleoside, which can be used for other purposes.</p>Formula:C31H33N3O7Purezza:Min. 95%Peso molecolare:559.61 g/mol5-Iodocytidine
CAS:<p>5-Iodocytidine is a nucleoside analogue that has been shown to possess potent antitumor activity. It is also used as a fluorescent probe for detection of uridine in biological samples. 5-Iodocytidine is structurally similar to uridine, which allows it to be taken up by cells and incorporated into RNA. This analog can also be detected with antibody response, as well as with the use of a fluorescence microscope. 5-Iodocytidine may have the potential to treat infectious diseases and autoimmune diseases because it binds to response elements on DNA and activates gene transcription.</p>Formula:C9H12IN3O5Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:369.11 g/molN6-Benzoyl-2',3'-isopropylideneadenosine
CAS:<p>N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.</p>Formula:C20H21N5O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:411.41 g/molRef: 3D-NB08544
Prodotto fuori produzioneN2-DMF-5'-O-DMT-2'-O-methylguanosine
CAS:<p>N2-DMF-5'-O-DMT-2'-O-methylguanosine is a novel nucleoside analog that has antiviral, anticancer and immunomodulating properties. It is synthesized from 2′,3′-dideoxyadenosine 5′-monophosphate by the condensation of 2,6-dimethylaniline with methylguanosine 5′-monophosphate and 5,6-dimethylaniline. The modification of the guanine base in N2-DMF-5'-O-DMT-2'-O-methylguanosine to an O6 -methyl group results in increased affinity for the ribonucleotide reductase enzyme (RNR) and inhibition of DNA synthesis.</p>Formula:C35H38N6O7Purezza:Min. 95%Peso molecolare:654.71 g/molRef: 3D-ND08425
Prodotto fuori produzione7-Cyano-7-deaza-2'-deoxyadenosine
CAS:<p>7-Cyano-7-deaza-2'-deoxyadenosine is a nucleoside analog that inhibits the growth of virus by competing with deoxyadenosine for incorporation into DNA and RNA. 7-Cyano-7-deaza-2'-deoxyadenosine also stabilizes dna duplexes and prevents them from breaking down. It has been shown to be effective against herpes simplex virus, which causes painful blisters on the skin or genitals. This drug has been used in clinical trials as an antiviral agent. 7-Cyano-7-deaza-2'-deoxyadenosine is synthesized from 2',3'-didehydrocytidine under the following conditions:</p>Formula:C12H13N5O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:275.26 g/molRef: 3D-NC144684
Prodotto fuori produzione2'-Deoxy-2'-fluoro-5-iodouridine
CAS:<p>2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside analog that is a modified version of uridine, where the 2'-fluoro modification is added to the sugar (deoxyribose), and an iodine atom is attached at the 5' position of the uracil base. This combination of modifications provides unique properties that may be useful for research and therapeutic applications.</p>Formula:C9H10FIN2O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:372.09 g/mol3'-O-Methyluridine
CAS:<p>3'-O-Methyluridine is a nucleoside that is used in the preparation of oligonucleotides and as a substrate for uridine phosphorylase. It is used to study the termination of RNA synthesis, which occurs when there are no more ribose residues in the RNA template strand. When this happens, an adenosine residue is added by polyphosphate kinase to the 3' end of the RNA strand. This addition causes a release of pyrophosphate and leads to end of DNA synthesis. The acid hydrolysis technique can be used to separate 3'-O-methyluridine from other nucleotides. This reaction produces guanosine, which can be detected using polymerase chain reaction (PCR) techniques such as polyacrylamide gel electrophoresis (PAGE).</p>Formula:C10H14N2O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:258.23 g/mol4-Hydroxy-6-methylpyrimidine
CAS:<p>4-Hydroxy-6-methylpyrimidine (4-OHMP) is a metabolite of trimethyltin. It is formed in the liver by methylation of 4,6-dimethylpyrimidine (4,6-DMPU). The levels of 4-OHMP in urine samples are used to monitor exposure to this agent. The median values for urinary concentrations of 4-OHMP are typically 10 times higher than those found in blood samples. The metabolite can be detected in urine up to 2 weeks after an individual’s last contact with trimethyltin. This compound has been shown to inhibit the synthesis of glycol dimethyl ethers and carbamates.</p>Formula:C5H6N2OPurezza:Min. 95%Peso molecolare:110.11 g/molRef: 3D-NH66985
Prodotto fuori produzione2'-Deoxy-6-O-methyl-guanosine
CAS:<p>2'-Deoxy-6-O-methyl-guanosine is a methylated nucleoside that has been shown to inhibit protein synthesis in cancer cells. It does so by inhibiting the synthesis of DNA, which is required for the production of proteins. This compound also inhibits monoclonal antibody production, which may be due to its ability to methylate DNA and prevent dna duplexes from being repaired. 2'-Deoxy-6-O-methyl-guanosine is used as a probe in the detection of human proteins by fluorescence spectroscopy. The sensitivity of this probe has been shown to be greater than 10 ng/mL, making it ideal for use in clinical settings where small quantities of proteins are present.</p>Formula:C11H15N5O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:281.27 g/mol7-Deaza-2'-deoxyinosine
CAS:<p>7-Deaza-2'-deoxyinosine is a purine nucleoside analog that has been shown to be a hydrogen bond donor and formamide acceptor. This drug destabilizes duplex DNA by interfering with the formation of the hydrogen bonds between the bases, which may result in strand breakage. 7-Deaza-2'-deoxyinosine has also been shown to inhibit RNA polymerase activity, thereby inhibiting protein synthesis. It has been used as a tool for studying enzyme mechanisms and in solid phase synthesis.</p>Formula:C11H13N3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:251.24 g/mol2'-Deoxy-8-oxo-adenosine
CAS:<p>2'-Deoxy-8-oxo-adenosine is a nucleoside that is a hydrogen bond donor. It is an analogue of adenosine, and has been shown to inhibit the growth of breast cancer cells. 2'-Deoxy-8-oxo-adenosine reacts with the enzyme dATP pyrophosphohydrolase to form 8-oxo-2'-deoxyadenosine, which inhibits mitochondrial DNA synthesis by preventing the incorporation of inorganic phosphate into mitochondrial DNA. This process leads to reduced ATP production, leading to cell death. The reactive properties of 2'-Deoxy-8-oxo-adenosine make it suitable for use as a probe molecule in chemical biology, as well as in biochemical studies on human serum.</p>Formula:C10H13N5O4Purezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:267.25 g/mol2,2'-Anhydrouridine
CAS:<p>The nucleophilic opening of 2,2'-Anhydrouridine represents a novel synthetic approach for elaborating the ring of nucleosides. For example, compounds such as 2-amino-, 2-fluoro- and 2-phenylseleno-2-deoxyuridines are prepared from the nucleophilic opening of 2,2'-Anhydrouridine.Â2,2'-Anhydrouridine inhibits uridine phosphorylase, a key enzyme targeted by some antitumor drugs.</p>Formula:C9H10N2O5Purezza:Min. 98 Area-%Colore e forma:White Off-White PowderPeso molecolare:226.19 g/molDiquafosol Impurity 2
CAS:<p>Diquafosol Impurity 2 is a high-purity phosphoramidite that can be used for the synthesis of DNA, RNA, and deoxyribonucleosides. This product is also a novel activator for phosphoramidites. Diquafosol Impurity 2 has CAS No. 63785-59-1 and a molecular weight of 228.24 g/mol. It is insoluble in water, but soluble in most organic solvents.</p>Formula:C18H25N4O20P3Purezza:Min. 95%Peso molecolare:710.33 g/mol7-Deaza-2'-C-methyladenosine
CAS:<p>Anti-HCV agent; inhibitor of viral RNA polymerases</p>Formula:C12H16N4O4Purezza:Min. 95 Area-%Colore e forma:Off-White PowderPeso molecolare:280.29 g/mol
