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Nucleosidi

Nucleosidi

I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.

Trovati 3569 prodotti di "Nucleosidi"

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  • 2'-Deoxy-5'-O-DMT-2-thio-N4-toluoylthymidine 3'-CE phosphoramidite

    CAS:
    <p>2'-Deoxy-5'-O-DMT-2-thio-N4-toluoylthymidine 3'-CE phosphoramidite is a novel nucleoside analogue with anticancer activity. It has been shown to inhibit the proliferation of human colon cancer cells in vitro, and inhibits the growth of HIV in cultured T-cells. In addition, this compound was found to be active against herpes virus.<br>2'-Deoxy-5'-O-DMT-2-thio-N4-toluoylthymidine 3'-CE phosphoramidite is a nucleoside analogue with ribonucleosides at the 2' and 5' positions, while the 4' position is modified by an acetyl group. This modification prevents incorporation into DNA or RNA, and so prevents viral replication.</p>
    Formula:C48H56N5O7PS
    Purezza:Min. 95%
    Peso molecolare:878.05 g/mol

    Ref: 3D-PD08805

    100mg
    589,00€
    250mg
    1.091,00€
  • 3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å


    <p>3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å is a monophosphate nucleoside that is used in the synthesis of DNA. It is an antiviral and anticancer drug that inhibits viral replication by competing with natural diphosphate nucleosides. 3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å also has shown to be effective against leukemia cells in vitro and has been shown to inhibit angiogenesis, which may be due to its ability to inhibit the proliferation of endothelial cells.</p>
    Purezza:Min. 95%

    Ref: 3D-ND11618

    1g
    300,00€
    2g
    376,00€
    5g
    717,00€
  • 4-Chloro-5-aminopyrimidine

    CAS:
    <p>4-Chloro-5-aminopyrimidine (4CAP) is an inhibitor of the enzyme purine nucleoside phosphorylase, which is involved in the synthesis of purines and pyrimidines. 4CAP has potent inhibitory activity with a Ki value of 0.06 μM, which is comparable to that of zebularine. 4CAP has also been shown to have antiinflammatory properties in lung tissue. The molecular modeling studies show that 4CAP binds to the hydroxyl group on the enzyme and prevents it from forming a covalent bond with its substrate. This causes a decrease in the rate of reaction time for the enzyme, resulting in decreased production of purines and pyrimidines.</p>
    Formula:C4H4ClN3
    Purezza:Min. 95%
    Peso molecolare:129.55 g/mol

    Ref: 3D-NC57423

    1g
    336,00€
    2g
    598,00€
    5g
    906,00€
    10g
    1.387,00€
    500mg
    300,00€
  • 4-Amino-6-hydroxy-2-methylpyrimidine

    CAS:
    <p>4-Amino-6-hydroxy-2-methylpyrimidine (4AMMP) is a heterocyclic compound that belongs to the group of pyrimidines. It has been shown to react with morpholine and acrylic acid in an oxidation sequence. The reaction proceeds through an elimination, forming formaldehyde, which condenses with hydrolyzed piperazine to give the final product. 4AMMP can also be alkylated with a variety of reagents such as methyl iodide or dimethyl sulfate.</p>
    Formula:C5H7N3O
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:125.13 g/mol

    Ref: 3D-NA44281

    10g
    303,00€
    25g
    329,00€
    50g
    494,00€
    100g
    701,00€
  • 3'-Azido-3'-deoxy-5'-O-tritylthymidine

    CAS:
    <p>An intermediate in the production of Zidovudine, the FDA approved medication for treatment of AIDS.</p>
    Formula:C29H27N5O4
    Purezza:Min. 98 Area-%
    Colore e forma:White Powder
    Peso molecolare:509.56 g/mol

    Ref: 3D-NA10412

    1g
    196,00€
    2g
    286,00€
    5g
    463,00€
    10g
    731,00€
    25g
    871,00€
  • 2',3'-Dideoxyuridine-5'-O-monothiophosphate

    CAS:
    2',3'-Dideoxyuridine-5'-O-monothiophosphate is an antiviral nucleoside that inhibits viral DNA synthesis. It is a phosphoramidate prodrug of the natural compound deoxyuridine monophosphate (dUMP). 2',3'-Dideoxyuridine-5'-O-monothiophosphate has been shown to be active against human papilloma virus and to inhibit the replication of some DNA viruses, including herpes simplex virus, cytomegalovirus, and Epstein-Barr Virus. This drug has also been shown to have anticancer activity in vitro and in vivo.
    Formula:C9H13N2O6PS
    Purezza:Min. 95%
    Peso molecolare:308.25 g/mol

    Ref: 3D-ND10394

    1µg
    303,00€
    5µg
    497,00€
    10µg
    736,00€
  • 5'-O-DMT-thymidine-3'-lcaa-CPG


    5'-O-DMT-thymidine-3'-lcaa-CPG is a nucleoside, ribonucleoside, and diphosphate that inhibits viral DNA synthesis. It is a novel compound with antiviral properties that has been shown to inhibit the replication of human cytomegalovirus (HCMV) and herpes simplex type 1 virus. 5'-O-DMT-thymidine-3'-lcaa-CPG also functions as an anticancer agent by inhibiting DNA synthesis in tumor cells. This nucleoside analog is phosphoramidite, which can be used for the preparation of modified oligonucleotides. 5'-O-DMT-thymidine-3'-lcaa-CPG has high purity and high quality.
    Purezza:Min. 95%
    Colore e forma:Powder

    Ref: 3D-ND57352

    25g
    273,00€
    50g
    437,00€
    100g
    668,00€
    250g
    1.219,00€
  • 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite

    CAS:
    8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel nucleoside analog with antiviral and anticancer properties. It is synthesized by reacting 8-aminoimidazo[2,1-b]thiazole 1,3(2H)-dione (AITD) with N6,N8-diisopropyl dATP to form the aminothiazole phosphate intermediate. This intermediate is then reacted with 5'-O-(4,4'-dimethoxytrityl)-2',3',5' triphosphate (DMTrP) to produce the desired product. The synthesis of 8AAODMTAP has been shown to be more efficient than other synthesized nucleosides due to its high purity and lack of impurities.
    Formula:C46H59N10O6P
    Purezza:Min. 95%
    Peso molecolare:879 g/mol

    Ref: 3D-PA09006

    250mg
    1.483,00€
  • 2',3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate)

    CAS:
    <p>2',3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) (2,3'-ddGTP) is a nucleoside that is synthesized using phosphoramidite chemistry. It has antiviral and anticancer activity, as well as the ability to activate cellular transcription. 2,3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) can be used in the synthesis of modified nucleosides or in the synthesis of novel nucleosides. The compound was found to inhibit DNA replication by binding to the enzyme ribonucleotide reductase. 2,3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) can also be used for DNA sequencing and as a cytotoxic agent in cancer chemotherapy.</p>
    Formula:C10H16N5O11P3S
    Purezza:Min. 95%
    Peso molecolare:507.25 g/mol

    Ref: 3D-ND10393

    1µg
    303,00€
    5µg
    516,00€
    10µg
    736,00€
  • 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine

    CAS:
    8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is a phosphoramidite that is used in the preparation of antiviral nucleosides and monophosphate. It has been shown to have anticancer activity. 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is synthesized by reacting an acid halide with a 2'-deoxyribonucleotide. This reaction produces a 2'-bromo adenosine derivative, which is then reacted with dimethylamine to produce the desired product. The synthesis of 8-bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine can be performed on a large scale using an automated process.
    Formula:C13H17BrN6O3
    Purezza:Min. 95%
    Peso molecolare:385.22 g/mol

    Ref: 3D-HIA90652

    250mg
    985,00€
  • 2-Methylthio-N6-methyladenosine

    CAS:
    <p>2-Methylthio-N6-methyladenosine is an adenosine nucleoside that is found in the DNA of eukaryotes. It is similar to 2-methylthio-n6-isopentenyladenosine, which is a modified form of n6-methyladenosine. The chemical structures of both molecules are related to the thermodynamic properties of the molecule and their ability to be postsynthetically modified. These modifications can lead to changes in their translation, which can have implications for the development and progression of disease. 2-Methylthio-N6-methyladenosine has a role in epigenetics, which is defined as changes in gene expression without any alterations in DNA sequence. In this case, it may modify the chloride ion concentration by changing its chemical structure, leading to epigenetic changes that can affect how genes are expressed or translated into proteins.</p>
    Formula:C12H17N5O4S
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:327.36 g/mol

    Ref: 3D-NM159489

    5mg
    731,00€
    10mg
    866,00€
    25mg
    1.334,00€
  • 2'-Deoxy-5-(trifluoromethyl)cytidine

    CAS:
    <p>2'-Deoxy-5-(trifluoromethyl)cytidine is a synthetic nucleoside analogue that inhibits the cytidine deaminase enzyme. It is used in the treatment of some types of leukemia and other cancers. The compound, which has a trifluoromethyl group on the 2' position, binds to the active site of cytidine deaminase and prevents it from functioning. This leads to an accumulation of thymidylate, which is required for DNA synthesis. The tumor tissue also contains high concentrations of this drug and its metabolites, making it more effective against cancer cells than normal cells. 2'-Deoxy-5-(trifluoromethyl)cytidine has been shown to inhibit anabolism in tumor tissue in the presence of high concentrations of phosphorylases, which are enzymes that catalyze reactions that break down carbohydrates and proteins into smaller molecules such as glucose or amino acids.</p>
    Formula:C10H12F3N3O4
    Purezza:Min. 95%
    Peso molecolare:295.22 g/mol

    Ref: 3D-NT11494

    5mg
    4.574,00€
  • 2-Methylthio-6-chloropurine

    CAS:
    <p>2-Methylthio-6-chloropurine riboside is a nucleotide analog that is used as a substrate to study the enzymatic modification of RNA. The compound has been synthesized by reacting 2-methylthio-6-chloropurine with ribose and purine bases in a postsynthetic modification. To detect the product, 2-methylthio-6-chloropurine riboside was labeled with 32P and then detected using mass spectrometry. In order to identify the structure of this compound, it was subjected to chromatography and spectroscopy. This process allowed for the identification of 2-methylthio-6-chloropurine riboside as an analog of N6 methyladenosine.</p>
    Formula:C6H5CIN4S
    Purezza:Min. 95%
    Peso molecolare:304.11 g/mol

    Ref: 3D-NM29024

    1g
    1.303,00€
    2g
    2.318,00€
    5g
    4.757,00€
  • 5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide

    CAS:
    <p>5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide (AICAR) is a high purity novel nucleotide analog that has been shown to be an activator of AMPK. AICAR can act as a substitute for ATP, the molecule that drives cellular energy production. AICAR has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound also inhibits viral RNA replication by competitively binding to the enzyme polymerase, which is essential for viral replication.</p>
    Formula:C15H20N4O8
    Purezza:Min. 95%
    Peso molecolare:384.34 g/mol

    Ref: 3D-NA11364

    2mg
    303,00€
    5mg
    414,00€
  • 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil


    5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is a phosphoramidite, activator, and synthetic nucleoside that has been modified to contain fluorine atoms. 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is an antiviral agent that was developed for the treatment of HIV/AIDS and cancer. It inhibits the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. This drug also has anticancer properties because it inhibits the synthesis of DNA in tumor cells and activates apoptosis, causing cell death.
    Purezza:Min. 95%

    Ref: 3D-NF58424

    25mg
    303,00€
    50mg
    370,00€
    100mg
    526,00€
    250mg
    1.033,00€
    500mg
    1.558,00€
  • Chemical phosphorylating reagent (cpr)

    CAS:
    Chemical phosphorylating reagent (CPR) is a powerful tool for the study of kinases, which are enzymes that regulate cellular processes such as cell division and apoptosis. CPR has been shown to be effective in inhibiting the activity of certain kinases that are involved in tumor growth and progression. It has also been used as an anticancer agent, inducing apoptosis in cancer cells. CPR is an analog of toxaphene and labetalol, two compounds with known kinase inhibitor activity. This reagent has been tested on human urine samples and Chinese hamster ovary cells, demonstrating its potential as a valuable research tool for studying kinase signaling pathways and developing new cancer therapies.
    Formula:C5H10O5
    Purezza:Min. 95%
    Peso molecolare:150.13 g/mol

    Ref: 3D-IEA78302

    5g
    1.014,00€
    10g
    1.387,00€
  • 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite

    CAS:
    <p>1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite is a novel nucleoside monophosphate that has been modified with fluorine at the 2' position and a deoxyribose sugar. 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite may be useful for antiviral treatment, as it can inhibit human immunodeficiency virus type 1 (HIV1) replication in vitro by inhibiting HIV1 reverse transcriptase. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis or promote apoptosis.</p>
    Formula:C39H46FN4O8P
    Purezza:Min. 95%
    Colore e forma:White To Off-White Solid
    Peso molecolare:748.8 g/mol

    Ref: 3D-PD09311

    1g
    669,00€
    5g
    2.442,00€
    250mg
    304,00€
    500mg
    396,00€
  • 1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil


    <p>1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil is a synthetic nucleoside that is activated by phosphorylation. This nucleoside is an antiviral and anticancer agent, and has been shown to be active against HIV, cytomegalovirus, herpes simplex virus type 1, and lymphocytic leukemia cells. It has also been shown to have anti-inflammatory properties. The compound is a monophosphate and diphosphate, which are more potent than the corresponding ribonucleosides. 1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil has CAS number 26582, high purity, high quality.</p>
    Formula:C28H23FN2O4
    Purezza:Min. 95%
    Peso molecolare:470.49 g/mol

    Ref: 3D-ND58413

    25mg
    303,00€
    50mg
    388,00€
    100mg
    552,00€
    250mg
    1.755,00€
    500mg
    2.733,00€
  • 1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol


    1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is an activator that can be used in the synthesis of DNA and RNA. It is a novel compound with antiviral properties and anticancer effects. It has been shown to have high purity and quality. This activator is a phosphoramidite that can be used in the synthesis of DNA or RNA and has been modified to have antiviral properties. It is synthesized using deoxyribonucleosides as starting materials, which are obtained from natural sources such as yeast extract or tryptophan.
    Formula:C22H25N5O5
    Purezza:Min. 95%
    Peso molecolare:439.48 g/mol

    Ref: 3D-NA07923

    5g
    Prezzo su richiesta
  • 2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine

    CAS:
    <p>2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a synthetic purine nucleoside analog. The fluorine substitution and sugar modification allow it to mimic natural nucleosides but disrupt DNA or RNA synthesis when incorporated. The fluorine makes the molecule more chemically stable and can influence how enzymes interact with it. Like other nucleoside analogs, it has the potential to act as a chain terminator or inhibit key enzymes like polymerases or reverse transcriptases.</p>
    Formula:C10H13FN6O3
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:284.25 g/mol

    Ref: 3D-ND09537

    1g
    1.248,00€
    2g
    2.203,00€
    5g
    5.143,00€
    250mg
    272,00€
    500mg
    410,00€
  • Acetoacetyl coenzyme A trisodium salt tetrahydrate

    CAS:
    <p>Acetoacetyl coenzyme A trisodium salt tetrahydrate is a novel antiviral agent that inhibits the synthesis of viral DNA and RNA. Acetoacetyl CoA has been shown to inhibit the replication of HIV, HSV-1 and HSV-2, influenza virus, and cytomegalovirus (CMV). The mechanism of action is not yet known but may be related to its ability to activate cellular DNA polymerase β. Acetoacetyl CoA also has a high purity and quality, as well as being modified for use in phosphoramidites.</p>
    Formula:C25H37N7Na3O18P3S·4H2O
    Purezza:Min. 96 Area-%
    Colore e forma:Powder
    Peso molecolare:989.62 g/mol

    Ref: 3D-NA47206

    10mg
    2.013,00€
    20mg
    3.172,00€
  • 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt


    <p>9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt is a modified nucleoside phosphoramidite. It is used as an antiviral and anticancer agent, as well as an activator in DNA synthesis. 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt has been shown to be active against HIV, herpes simplex virus type 1, herpes simplex virus type 2, cytomegalovirus, influenza A virus, and human papillomavirus types 16 and 18.</p>
    Formula:C39H39FN5O10·C6H16N
    Purezza:Min. 95%
    Peso molecolare:858.97 g/mol

    Ref: 3D-ND09136

    10mg
    414,00€
    25mg
    663,00€
    50mg
    1.118,00€
    100mg
    1.973,00€
    250mg
    3.203,00€
  • 2'-13CCytidine

    CAS:
    <p>2'-13CCytidine is a cytidine nucleoside that inhibits the synthesis of RNA and DNA in cells. It is an analog of cytarabine, which is a pyrimidine nucleoside and an antineoplastic agent. 2'-13CCytidine has been shown to be effective as an antiviral agent against HIV-1 and HSV-2, as well as an immunosuppressant for the treatment of autoimmune diseases such as rheumatoid arthritis. This drug is used in chemotherapy to inhibit cell division in leukemia.</p>
    Formula:CC8H13N3O5
    Purezza:Min. 95%
    Peso molecolare:244.21 g/mol

    Ref: 3D-NC34302

    50mg
    491,00€
    100mg
    759,00€
  • Adenosine 5'-(tetrahydrogen triphosphate)

    CAS:
    <p>Adenosine is a nucleoside consisting of adenine and ribose. It is used in biochemical analysis to quantify the cytosolic Ca2+ concentration, which is an important cellular signal that regulates many cellular processes. Adenosine stimulates the uptake of Ca2+ by binding to the monophosphate-activated protein (AMPAR), which results in the opening of voltage-gated calcium channels. These channels allow Ca2+ to enter the cell, increasing its intracellular concentration. Adenosine also has been shown to stimulate muscle contraction through increased release of Ca2+. This drug also possesses inhibitory effects on synaptic transmission and may have anti-inflammatory properties due to its ability to inhibit proteolytic enzymes in muscle cells.</p>
    Formula:C10H14MgN5O13P3
    Purezza:Min. 95%
    Peso molecolare:529.47 g/mol

    Ref: 3D-BAA47684

    25mg
    303,00€
    50mg
    310,00€
    100mg
    465,00€
    250mg
    736,00€
    500mg
    1.110,00€
  • 2,2-Crylo-5-methyluridine


    2,2-Crylo-5-methyluridine is a synthetic diphosphate nucleotide that has been shown to be an activator of DNA synthesis. It is used in the synthesis of oligonucleotides and as a monophosphate for the synthesis of 2'-O-methyl ribonucleosides. 2,2-Crylo-5-methyluridine has been shown to have anticancer activity, which may be due to its ability to inhibit tumor proliferation or induce apoptosis.
    Purezza:Min. 95%

    Ref: 3D-NC04077

    1g
    2.440,00€
  • 5'-O-Acetyl-2',3'-dideoxyinosine

    CAS:
    <p>5'-O-Acetyl-2',3'-dideoxyinosine is a nucleoside analogue that inhibits viral replication. It is a potent activator of the immune system and has been shown to be effective against cancer cells. 5'-O-Acetyl-2',3'-dideoxyinosine was originally synthesized as an antiviral agent, but it was found to be ineffective in this function. The drug binds to the ribonucleotide reductase enzyme, which converts ribonucleotides into deoxyribonucleotides and is essential for the production of DNA. The drug blocks the conversion of ribonucleotides into deoxyribonucleotides, preventing DNA synthesis and replication. This drug has also been shown to have anticancer activity by inhibiting DNA synthesis and cell division.</p>
    Formula:C12H14N4O4
    Purezza:Min. 95%
    Peso molecolare:278.26 g/mol

    Ref: 3D-NA08461

    10g
    303,00€
    25g
    369,00€
    50g
    525,00€
  • 2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine

    CAS:
    <p>2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine is a nucleoside analog that acts as a DNA and RNA activator. It is used as a component in antiviral drugs, anticancer drugs, and antiretroviral drugs. This compound is structurally similar to the natural nucleosides adenosine and cytidine. It has been shown to inhibit the growth of various cancer cell lines with IC50 values ranging from 6.5 to 25 nM.</p>
    Formula:C11H8F3N3
    Purezza:Min. 95%
    Peso molecolare:239.2 g/mol

    Ref: 3D-NA57415

    1g
    300,00€
    2g
    343,00€
    5g
    478,00€
  • 2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt

    CAS:
    2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt (2'-dO-5HmcMP) is a nucleoside analogue that inhibits the activity of reverse transcriptase, an enzyme required for replication of HIV. This compound is phosphorylated in vivo to 2'-dO-5HmcMP monophosphate, which then competitively inhibits the binding of dNTPs to the enzyme and prevents DNA synthesis. 2'-dO-5HmcMP also has anticancer activity and has been shown to inhibit the proliferation of cells in vitro. 2'-dO-5HmcMP has no significant toxicity to humans or other mammals.
    Purezza:Min. 95%

    Ref: 3D-ND177173

    25mg
    2.440,00€
  • 1-(2-Deoxy- 2, 2- difluoro- b- D- xylofuranosyl)cytosine

    CAS:
    <p>1-(2-Deoxy-2,2-difluoro-beta-D-xylofuranosyl)cytosine is a nucleoside (a compound consisting of a nucleotide base linked to a sugar). It is a modified form of cytosine that has been phosphorylated at the 2’ position. 1-(2-Deoxy-2,2-difluoro-beta-D-xylofuranosyl)cytosine has antiviral and anticancer activity through its ability to inhibit viral DNA synthesis and activate the immune system. This drug also has antitumor activity due to its ability to inhibit the tumor growth factor beta (TGFB). 1-(2-Deoxy-2,2-difluoro-beta-D -xylofuranosyl)cytosine can be used in cancer treatment as an anticancer agent.</p>
    Formula:C9H11F2N3O4
    Purezza:Min. 95%
    Peso molecolare:263.2 g/mol

    Ref: 3D-ND158439

    1mg
    1.253,00€
    2mg
    1.879,00€
    5mg
    2.440,00€
    10mg
    3.050,00€
  • 2',3'-Stannyluridine


    <p>2',3'-Stannyluridine is a novel modified ribonucleoside. It is synthesized by the condensation of 2'-deoxyuridine and 3'-hydroxy-2-methylpropiophenone. This product has been shown to have anticancer and antiviral activities. 2',3'-Stannyluridine inhibits the synthesis of DNA, RNA, and protein in cells by binding to the ribonucleotide reductase enzyme. It also has an effect on phosphoramidite synthesis, which is an important step in DNA replication. The CAS number for this product is 57824-03-1.</p>
    Purezza:Min. 95%

    Ref: 3D-NS158811

    2g
    303,00€
    5g
    336,00€
    10g
    491,00€
    25g
    997,00€
  • 2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt

    CAS:
    <p>2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt (2'OMeEtGTP) is an antiviral agent that is used as a component of an antiviral drug. It inhibits the viral enzyme DNA polymerase, which prevents viral replication and transcription. This compound has been shown to have anticancer properties in vitro and in vivo in rat models. 2'OMeEtGTP is synthesized by reacting the nucleoside phosphoramidite 2'OMeEtGTP with triethylammonium phosphate (TEAP).</p>
    Purezza:Min. 95%

    Ref: 3D-NM162963

    10mg
    4.087,00€
  • Cytidine-5'-triphosphate, lithium salt


    Cytidine-5'-triphosphate, lithium salt (CTP, Li) is a monophosphate that is used as a cofactor in the synthesis of DNA and RNA. It is also used for the treatment of viral infections. CTP, Li has antiviral activity against herpes simplex virus type 1 and 2 (HSV-1 and HSV-2), varicella zoster virus (VZV), human cytomegalovirus (CMV) and Epstein-Barr virus (EBV). CTP, Li can be used to inhibit the growth of cancer cells by modifying DNA.
    Purezza:Min. 95%

    Ref: 3D-NC32076

    1g
    2.440,00€
  • 6-Propylamino-7-deazapurine

    CAS:
    <p>6-Propylamino-7-deazapurine is a synthetic nucleoside with antiviral and anticancer properties. It is an activator of DNA synthesis and is modified to have a high quality. 6-Propylamino-7-deazapurine has been shown to be effective against HIV and other viruses in vitro, as well as in animal models, but it is not yet approved for use in humans.6-Propylamino-7-deazapurine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>
    Formula:C9H12N4
    Purezza:Min. 95%
    Peso molecolare:176.22 g/mol

    Ref: 3D-NP11710

    1g
    1.127,00€
    100mg
    303,00€
    200mg
    473,00€
    500mg
    731,00€
  • 5'-O-DMT-2'-O-(2-methoxyethyl)uridine

    CAS:
    <p>5'-O-DMT-2'-O-(2-methoxyethyl)uridine is a modified nucleoside that is an antiviral and anticancer agent. It was first synthesized in the early 1980s, and has been shown to be active against a variety of viruses, such as herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). 5'-O-DMT-2'-O-(2-methoxyethyl)uridine inhibits the growth of cancer cells by interfering with DNA synthesis. This drug also has been shown to be an activator for DNA polymerases and is used as a building block for antiretroviral drugs.</p>
    Formula:C33H36N2O9
    Purezza:Min. 95%
    Peso molecolare:604.65 g/mol

    Ref: 3D-ND76851

    50g
    3.335,00€
  • 4'-Azidothymidine 5-triphosphate

    CAS:
    <p>4'-Azidothymidine 5-triphosphate (4AZTTP) is a deoxyribonucleoside that has been synthesized as an analog to thymidine. It has potent inhibitory activity against human immunodeficiency virus (HIV), and has been shown to be more effective than 2',3'-dideoxyinosine in inhibiting HIV replication. 4AZTTP inhibits the viral enzyme reverse transcriptase, which is crucial for the replication of HIV. This drug is activated by cellular enzymes and phosphorylated to 4'-azidothymidine 5'-triphosphate monophosphate, which can then bind to the viral DNA template and inhibit synthesis of RNA strands. The kinetic properties of 4AZTTP have been studied in detail using human lymphocytes as a model system for HIV infection.</p>
    Formula:C10H16N5O14P3
    Purezza:Min. 95%
    Peso molecolare:523.18 g/mol

    Ref: 3D-NA13340

    1g
    2.440,00€
  • 2’,3’,5’-Tri-O-(tert-butyldimethylsilyl)-adenosine


    <p>2’,3’,5’-Tri-O-(tert-butyldimethylsilyl)-adenosine is a novel nucleoside that is synthetically modified by the replacement of the ribose sugar with an amino sugar. The modification of the sugar reduces the likelihood of hydrolysis to ribose and phosphate. This product has shown anticancer effects against human tumor cells in vitro and in vivo. It also has antiviral activities against herpes simplex virus type 1 (HSV-1). 2’,3’,5’-Tri-O-(tert-butyldimethylsilyl)-adenosine is a monophosphate nucleoside that inhibits DNA synthesis by inhibiting DNA polymerase. It acts as a competitive inhibitor for deoxyribonucleotides and phosphoramidites, which are used in DNA synthesis. 2’,3’,5’-</p>
    Purezza:Min. 95%

    Ref: 3D-NT167521

    1g
    329,00€
    500mg
    300,00€
  • 5'-O-DMT-2'-O-hexylamino-5-methyluridine

    CAS:
    5'-O-DMT-2'-O-hexylamino-5-methyluridine is a nucleoside analog that is used in cancer treatment. It is synthesized by the chemical modification of uridine, which is converted to 5'-O-DMT-2'-O-hexylamino-5-methyluridine by reacting with 2',3'-dideoxyadenosine and 5,6,7,8,-tetrahydroisoquinoline. The monophosphate form of 5'-O-DMT-2'-O-hexylamino-5-methyluridine may be converted to the diphosphate form by phosphorylation with ATP. In addition to its anticancer effects, 5'-O-DMT-2'-O-hexylamino-5-methyluridine has antiviral and antiretroviral effects due to its inhibition of viral DNA synthesis.
    Formula:C37H45N3O8
    Purezza:Min. 95%
    Peso molecolare:659.79 g/mol

    Ref: 3D-ND08520

    25mg
    303,00€
    50mg
    353,00€
    100mg
    497,00€
    250mg
    793,00€
  • 9-(2-C-Methyl-b-D-ribofuranosyl)purine

    CAS:
    <p>9-(2-C-Methyl-b-D-ribofuranosyl)purine is a nucleoside that is used as an activator in the synthesis of phosphoramidites. 9-(2-C-Methyl-b-D-ribofuranosyl)purine has antiviral and anticancer properties, and it also inhibits the growth of bacteria. This nucleoside is synthesized from 2,4,6-trichlorophenylisocyanate and 5'-O-(4,4'-dimethoxytrityl)-beta-D-ribofuranose. The chemical name for 9-(2-C methyl b D ribofuranosyl)purine is 690269 - 86 - 4.</p>
    Formula:C11H14N4O4
    Purezza:Min. 95%
    Peso molecolare:266.25 g/mol

    Ref: 3D-NM144529

    ne
    Prezzo su richiesta
  • 2′-O-Succinyladenosine 3′,5′-monophosphate

    CAS:
    <p>Please enquire for more information about 2′-O-Succinyladenosine 3′,5′-monophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C14H16N5O9P
    Purezza:Min. 95%
    Peso molecolare:429.28 g/mol

    Ref: 3D-NS184178

    5mg
    607,00€
    10mg
    806,00€
    25mg
    1.518,00€
    50mg
    1.735,00€
    100mg
    1.952,00€
  • Fluorescein alkynylamino-ATP - 1.0 mM solution

    CAS:
    <p>Fluorescein alkynylamino-ATP is a fluorescent nucleotide analog that is used in molecular biology for the detection of DNA. It is labeled with tetramethylrhodamine, which can be detected using a fluorescence microscope. Fluorescein alkynylamino-ATP is a postsynthetic modification to DNA, which means it is added after the DNA has been synthesized. This molecule can be incorporated into the growing strand by either monoaddition or polymerase extension. Fluorescein alkynylamino-ATP binds to the 3' end of a primer during polymerase chain reaction (PCR) and can be detected using electrophoresis and sequence analysis.</p>
    Formula:C41H41N6O20P3
    Purezza:Min. 95%
    Peso molecolare:1,030.71 g/mol

    Ref: 3D-NF16725

    25µg
    700,00€
  • 5,6-Dihydro-5'-O-DMT-thymidine 3'-CE phosphoramidite


    This is a synthetic DNA analogue that is used in the synthesis of oligonucleotides. It is a phosphoramidite in which the 5,6-dihydro-5'-O-DMT group has been modified to allow for incorporation into DNA and RNA. This compound has antiviral and anticancer activities.
    Formula:C40H51N4O8P
    Purezza:Min. 95%
    Peso molecolare:746.83 g/mol

    Ref: 3D-PD09179

    250mg
    1.047,00€
  • 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine


    <p>3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine is a novel nucleoside analogue with high purity and quality. It is a DNA activator that has been shown to be active against both RNA and DNA viruses. 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine phosphorylates to the corresponding monophosphate, which inhibits viral DNA synthesis by competitive inhibition of diphosphate formation. This compound has also been shown to be an effective inhibitor of HIV replication in vitro.</p>
    Formula:C24H20N8O4
    Purezza:Min. 95%
    Peso molecolare:484.47 g/mol

    Ref: 3D-NA08672

    1mg
    303,00€
    5mg
    537,00€
    10mg
    814,00€
  • 5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite


    <p>5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It has been shown to have anticancer properties by inhibiting the growth of cancer cells. 5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is synthesized from the monophosphate form and can be used for the synthesis of both DNA and RNA.</p>
    Formula:C39H49N4O8P
    Purezza:Min. 95%
    Peso molecolare:732.82 g/mol

    Ref: 3D-PD09180

    250mg
    1.047,00€
  • 1-(3'-O-Nosyl-5'-O-trityl-2'-deoxy-b-D-lyxofuranosyl)thymine

    CAS:
    <p>Ribonucleosides are nucleosides that contain ribose as their pentose sugar. Ribonuclesides are synthetic, modified ribonucleosides that have been modified to include a 2'-deoxy-b-D-lyxofuranosyl group at the 3' position. Ribonuclesides activate antiviral activity by inhibiting viral DNA synthesis and protein synthesis. They also inhibit cancer cell proliferation by inhibiting DNA synthesis and RNA synthesis.</p>
    Formula:C35H31N3O9S
    Purezza:Min. 95%
    Peso molecolare:669.7 g/mol

    Ref: 3D-NN07310

    50mg
    303,00€
    100mg
    416,00€
  • 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate


    <p>2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate is a novel synthetic nucleoside analog with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine has been shown to be effective against human leukemia cells in vitro and in vivo.</p>
    Formula:C10H17ClN5O12P3
    Purezza:Min. 95%
    Peso molecolare:527.64 g/mol

    Ref: 3D-NA09401

    1µg
    303,00€
    5µg
    663,00€
    10µg
    977,00€
  • N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate


    <p>N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate is a synthetic nucleoside that has antiviral activity. It is a modification of the natural nucleoside cytidine, where the 4th position of the ribose ring is substituted with an acetyl group and the 2' position of the sugar moiety is substituted with a 2' deoxyribofuranosyl group. N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate inhibits viral replication by inhibiting viral RNA synthesis. Its antiviral properties may be due to its ability to inhibit DNA polymerase and reverse transcriptase, which are enzymes that synthesize DNA from RNA.</p>
    Purezza:Min. 95%

    Ref: 3D-NA158778

    25mg
    303,00€
    50mg
    355,00€
  • 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine

    CAS:
    <p>3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine is a novel antiviral agent that is synthesized as a deoxyribonucleoside monophosphate. It inhibits viral DNA polymerase and RNA synthesis by competitively inhibiting the incorporation of diphosphates into viral DNA. It has been shown to be active against herpes simplex virus type 1 and 2, vaccinia virus, influenza A virus, and Sindbis virus. 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine has also been shown to have anticancer properties in vitro and in vivo.</p>
    Formula:C21H23N5O6
    Purezza:Min. 95%
    Peso molecolare:441.44 g/mol

    Ref: 3D-ND16695

    10mg
    303,00€
    25mg
    401,00€
    50mg
    649,00€
    100mg
    1.052,00€
    250mg
    1.918,00€
  • Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution


    <p>Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a monoclonal antibody. It is used in the diagnosis of lung cancer. The antibody binds to markers present on the tumor cells and can be detected by immunohistochemistry (IHC) or immunofluorescence (IF). The antibody may also be used to identify submucosal tumors that are not palpable.</p>
    Formula:C22H34N5O17P3S·xLi
    Purezza:Min. 95%
    Peso molecolare:765.52 g/mol

    Ref: 3D-NB32054

    1g
    2.440,00€
  • Adenosine 5'-triphosphate trisodium salt

    CAS:
    <p>ATP is an important molecule in the body that is involved in a number of cellular processes, including energy production and transmission. It has been shown to be tumorigenic and is found at high levels in plasma membranes and muscle cells. ATP binds to the adenylate cyclase enzyme in the cell membrane and stimulates its activity, which increases intracellular levels of cyclic AMP (cAMP). Cyclic AMP activates protein kinase A, which phosphorylates proteins, leading to a cascade of reactions that result in cellular changes. ATP also has pharmacological effects on the plasma membrane by increasing its permeability to certain ions such as potassium ions. This leads to an increase in the rate of depolarization of the cell membrane, which causes an influx of calcium ions into the cell.</p>
    Formula:C10H15N5O13P3Na3
    Purezza:Min. 95%
    Peso molecolare:575.14 g/mol

    Ref: 3D-NA02978

    1g
    2.440,00€
  • 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine

    CAS:
    <p>3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine is a nucleoside that is used in the antiviral drug Aciclovir. It is an analog of 2'-deoxyadenosine and inhibits viral DNA synthesis by acting as a chain terminator. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine has shown some anticancer activity against human tumor cells in culture, but its mechanism of action is not well understood.</p>
    Formula:C23H17Cl2FN2O7
    Purezza:Min. 95%
    Peso molecolare:523.29 g/mol

    Ref: 3D-ND22464

    5mg
    303,00€
    10mg
    401,00€
    25mg
    650,00€
    50mg
    1.055,00€
    100mg
    1.916,00€
  • N6-Benzyladenosine 5'-triphosphate triethylammonium salt

    CAS:
    <p>N6-Benzyladenosine 5'-triphosphate triethylammonium salt is a hydrogen bond donor that is not naturally occurring. It has been shown to be a potent and selective analog of ATP with high specificity for cGMP-dependent protein kinase. This drug has been used to study the function of serotonin receptors, tyrosine kinases, and epidermal growth factor receptors. N6-Benzyladenosine 5'-triphosphate triethylammonium salt has also been shown to increase the sensitivity of cells to epidermal growth factor and to inhibit the reuptake of serotonin.END&gt;</p>
    Formula:C19H26N5O11P3·C18H48N3
    Purezza:Min. 95%
    Peso molecolare:899.95 g/mol

    Ref: 3D-NB04595

    1mg
    303,00€
  • 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:
    <p>3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is an inhibitor of the enzyme kinase. The active form of 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution inhibits human immunodeficiency virus (HIV) reverse transcriptase, preventing the synthesis of viral DNA. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to inhibit cancer cell growth in culture and to inhibit cancer cell proliferation in mice. This compound is also active against cancer cells that are resistant to other anti-cancer drugs. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is phosphorylated by cellular kinases, which may be</p>
    Formula:C10H16N5O13P3·xLi
    Purezza:Min. 95%
    Colore e forma:Colorless Clear Liquid
    Peso molecolare:507.18 g/mol

    Ref: 3D-NA32049

    1mg
    495,00€
    2mg
    888,00€
    5mg
    1.872,00€
    500µg
    341,00€
  • 3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine


    <p>3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is an antiviral agent that inhibits the production of virus particles by inhibiting DNA and RNA synthesis. It is a modified nucleoside analog that has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. This drug has also been shown to be effective against leukemia and lymphoma cells, as well as other types of cancer cells. 3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is used for the treatment of AIDS, hepatitis B, hepatitis C, herpes zoster (shingles), and other diseases caused by viruses. It can be administered orally or intravenously.</p>
    Formula:C28H33FN2O6Si
    Purezza:Min. 95%
    Peso molecolare:540.66 g/mol

    Ref: 3D-NA08463

    25mg
    303,00€
    50mg
    414,00€
    100mg
    663,00€
    250mg
    1.047,00€
  • 2-Methylthioadenosine-5'-triphosphate

    CAS:
    2-Methylthioadenosine-5'-triphosphate (2MeSATP) is a nucleotide analogue that inhibits the synthesis of ATP by binding to the adenylate cyclase enzyme. 2MeSATP has been shown to be a potent inhibitor of neuronal death and is used as a tool in cellular research. 2MeSATP binds to guanine nucleotide-binding protein (G protein), which inhibits its activity and prevents the activation of other downstream enzymes, such as phospholipase C, which are necessary for neurotransmitter release. 2MeSATP also has an inhibitory effect on several other enzymes, including phosphodiesterases and cyclases, in cellular models and whole cells.
    Formula:C11H18N5O13P3S
    Purezza:Min. 95%
    Peso molecolare:553.27 g/mol

    Ref: 3D-NM72044

    5mg
    729,00€
    10mg
    921,00€
    25mg
    1.356,00€
    50mg
    2.324,00€
    2500µg
    486,00€
  • Biotin-5-deoxyuridine-5'-triphosphate, lithium salt - 1 mM aqueous solution


    <p>Biotin-5-deoxyuridine-5'-triphosphate, lithium salt is a novel phosphoramidite. It has been shown to be an anticancer agent and antiviral agent. Biotin-5-deoxyuridine-5'-triphosphate, lithium salt inhibits the growth of cancer cells by binding to the ribonucleotide reductase enzyme, thereby preventing synthesis of DNA and RNA.</p>
    Formula:C22H34N5O16P3S·xLi
    Purezza:Min. 95%
    Peso molecolare:749.52 g/mol

    Ref: 3D-NB32060

    1g
    2.440,00€
  • 5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine


    <p>5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral drug that has been shown to inhibit the synthesis of viral RNA by inhibiting the activity of DNA polymerase. It is a novel antiviral drug with high purity and can be used for cancer treatment as well. 5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also has a novel mechanism of action, which is different from other antiviral drugs such as ribonucleosides or deoxyribonucleosides. This compound is used in the synthesis of phosphoramidites for oligonucleotide synthesis.</p>
    Formula:C17H27IN4O3Si
    Purezza:Min. 95%
    Peso molecolare:490.41 g/mol

    Ref: 3D-NB165192

    1g
    2.349,00€
    2g
    3.803,00€
    500mg
    1.568,00€
  • a-Nicotinamide adenine dinucleotide phosphate

    CAS:
    <p>a-Nicotinamide adenine dinucleotide phosphate (NADP) is a modified form of the natural coenzyme nicotinamide adenine dinucleotide (NAD) and is an important component in cellular metabolism. NADP is also an anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It is used for the treatment of viral infections such as cytomegalovirus (CMV), herpes simplex virus (HSV), varicella zoster virus (VZV), and Epstein-Barr virus (EBV). NADP is also a novel antiviral agent that has been shown to inhibit the enzyme diphosphate kinase, which prevents the production of ATP. This inhibition leads to cell death by disrupting normal energy production. NADP has been shown to be effective against CMV isolates resistant to ganciclovir or foscarnet due to its ability to inhibit DNA synthesis.</p>
    Formula:C21H28N7O17P3
    Purezza:Min. 95%
    Peso molecolare:743.41 g/mol

    Ref: 3D-NN29116

    1g
    2.440,00€
  • 2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt

    CAS:
    <p>2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt (ddI-TP) is a nucleoside analog that inhibits HIV replication by competing with natural nucleosides for binding to HIV reverse transcriptase. ddI-TP acts as an inhibitor of human mitochondrial DNA polymerase γ, and blocks the synthesis of fatty acids in mouse cells. It is also able to inhibit signal pathways involving protein kinases and phosphatases. ddI-TP has been shown to be effective against hiv infection in mice. This drug can be used in the treatment of hiv infection, as well as in the prevention of its transmission from mother to child during pregnancy and breastfeeding.</p>
    Formula:C10H15N4O12P3
    Purezza:Min. 95%
    Peso molecolare:476.17 g/mol

    Ref: 3D-ND10277

    5mg
    4.224,00€
  • 8-Bromo-5'-o-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine

    CAS:
    8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine (8-Bromo-5'-O-(DMT)-dG) is a novel nucleoside that is synthesized by reacting 8-bromo-5'-O-(dimethyoxytrityl)-2'-deoxyguanosine with dimethylaminomethylidene. It has antiviral, anticancer, and ribonucleoside activities. 8-Bromo-5'-O-(DMT)-dG is used as a building block for the synthesis of oligonucleotides, phosphoramidites, and other modified nucleosides. 8-Bromo-5'-O-(DMT)-dG is currently being developed as an anticancer drug.
    Formula:C34H35BrN6O6
    Purezza:Min. 95%
    Peso molecolare:703.6 g/mol

    Ref: 3D-EIA58253

    500mg
    1.008,00€
  • 4-(Dimethoxymethyl)pyrimidine

    CAS:
    <p>4-(Dimethoxymethyl)pyrimidine is a nitrogen heterocycle that is prepared by the reaction of formamide and nitrate. This compound has been shown to inhibit the replication of viruses such as HIV, herpes simplex virus type 2 (HSV-2), or vesicular stomatitis virus (VSV). 4-(Dimethoxymethyl)pyrimidine also binds to uracil in RNA, inhibiting RNA synthesis and leading to cell death. This compound can also be used as a precursor for the preparation of 2-aminopyrimidine, which is used in the synthesis of other compounds. 4-(Dimethoxymethyl)pyrimidine is used in organic synthesis for the preparation of benzene derivatives, such as nitrobenzene. This compound can also be synthesized by reacting formamide with toluene in an ultrasonic bath.</p>
    Formula:C7H10N2O2
    Purezza:Min. 95%
    Peso molecolare:154.17 g/mol

    Ref: 3D-ND57369

    1g
    470,00€
    2g
    645,00€
    5g
    962,00€
    500mg
    300,00€
  • 2'-Deoxy-2'-fluoroguanosine-5'-monophosphate

    CAS:
    <p>2'-Deoxy-2'-fluoroguanosine-5'-monophosphate is a phosphoramidite monoester with a diphosphate group that has been synthetically modified to provide antiviral and anticancer activity. It is an activator of DNA synthesis and inhibits the proliferation of tumor cells by interfering with DNA replication. The compound is also used as a precursor for the synthesis of 2'-deoxy-2'-fluoroguanosine, which has potent anti-HIV activity.</p>
    Formula:C10H13FN5O7P
    Purezza:Min. 95%
    Peso molecolare:365.21 g/mol

    Ref: 3D-ND145454

    10mg
    2.257,00€
  • 2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine

    CAS:
    <p>2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine is a monophosphate nucleoside analog that has antiviral activity against the Herpes virus. It is a cytosine analog that is incorporated into DNA and inhibits viral replication. 2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine has also been shown to have anticancer properties and high purity. This compound is synthesized by the reaction of 2'-deoxycytidine and 4-(2,2,2,-trimethylpropionyl)-1,3-butanediol with O-(7-azabenzotriazol-1-yl) N,N,N',N' tetramethyluronium hexafluorophosphate (HATU) in anhydrous pyridine. The CAS number for this compound is 10089862.</p>
    Formula:C34H37N3O7
    Purezza:Min. 95%
    Peso molecolare:599.69 g/mol

    Ref: 3D-ND02997

    2g
    315,00€
    5g
    470,00€
    10g
    717,00€
  • XTT, sodium salt

    CAS:
    <p>XTT is a tetrazolium compound that can be used to measure the activity of enzymes. It has been shown to inhibit the growth of tumor cells in vitro and in vivo. XTT can also be used as an antibacterial agent against C. glabrata and as an anthelmintic drug against tapeworms. This compound is not active against other bacteria, such as E. coli or S. aureus, because they are resistant to oxidative injury and have high levels of ABCG2 (ATP-binding cassette G2), which prevents intracellular accumulation of XTT.</p>
    Formula:C22H16N7NaO13S2
    Peso molecolare:673.53 g/mol

    Ref: 3D-X-5000

    1g
    Prezzo su richiesta
    100mg
    Prezzo su richiesta
    250mg
    Prezzo su richiesta
    500mg
    Prezzo su richiesta
    2500mg
    Prezzo su richiesta
    -Unit-gg
    Prezzo su richiesta
  • 2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine

    CAS:
    <p>2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine is a novel modified nucleoside with antiviral activity. It has been shown to inhibit the replication of the influenza A virus in cell culture and animal models. 2′Amino-6′chloro 9-(2′deoxy 3′,5′di O′benzoyl 2′fluoro b D arabinofuranosyl)purine is an analog of adenosine that has shown anticancer activity in vitro and in vivo. It inhibits DNA synthesis by inhibiting deoxyribonucleotide synthesis and ribonucleotide synthesis. This drug also inhibits cell proliferation and induces apoptosis.</p>
    Formula:C24H19ClFN5O5
    Purezza:Min. 95%
    Peso molecolare:511.89 g/mol

    Ref: 3D-NA31237

    1g
    516,00€
    2g
    726,00€
    5g
    1.381,00€
    10g
    1.973,00€
    25g
    4.003,00€
  • 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine

    CAS:
    <p>3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that is used in the synthesis of oligonucleotides. It is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to have high purity and quality. The synthesis of this compound involves the use of a novel activator, which is also available for purchase from this website. This nucleoside has been modified with tert-butyldimethylsilyl groups at the 3' and 5' positions of the ribose moiety, which prevents the hydrolysis of the phosphate ester bond by alkaline phosphatase enzymes, thus allowing for sequence determination.</p>
    Purezza:Min. 95%

    Ref: 3D-NB15555

    1g
    857,00€
    2g
    1.441,00€
    5g
    2.745,00€
    10g
    4.452,00€
  • 1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione

    CAS:
    <p>1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione is an organic semiconductor material. It is a dielectric with a high transition temperature and good electrical conductivity. This compound is a metal silicide with a low resistivity and high electron mobility. It can be used as an active layer in thin film transistors or as a field effect transistor channel material. 1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione has been shown to have good chemical stability and thermal stability in air at temperatures up to 400°C.</p>
    Purezza:Min. 95%

    Ref: 3D-ND44283

    1g
    300,00€
  • Adenylosuccinic acid

    CAS:
    <p>Adenylosuccinic acid is an organic acid that is synthesized through the deamination of adenosine monophosphate. It is used in transfection experiments to inhibit polymerase chain reaction (PCR) and reverse transcriptase. Adenylosuccinic acid inhibits DNA synthesis by targeting enzymes such as the ribonucleotide reductase and the DNA polymerase β-subunit. Adenylosuccinic acid also inhibits protein synthesis, which may be due to its ability to inhibit energy metabolism, leading to cellular death. This drug has been shown to have a wide range of pharmacological effects, including anti-inflammatory, analgesic, and antifungal activity.</p>
    Formula:C14H18N5O11P
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:463.29 g/mol

    Ref: 3D-FA159229

    5mg
    342,00€
    10mg
    486,00€
    25mg
    978,00€
    50mg
    1.518,00€
  • N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine


    <p>N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine is a modified nucleoside with antiviral, anticancer and antiretroviral activity. It is a novel monophosphate that has been shown to be effective against hepatitis B and HIV. N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine inhibits the synthesis of viral DNA by acting as an activator of DNA polymerases.</p>
    Purezza:Min. 95%

    Ref: 3D-NI167500

    100mg
    303,00€
  • 2'-TFA-NH-dC

    CAS:
    <p>2'-TFA-NH-dC is a novel nucleoside analogue that has been modified to have antiviral and anticancer properties. The chemical structure of 2'-TFA-NH-dC closely resembles dC, which is a natural DNA nucleotide, but with the addition of an extra fluorine atom at the 2' position. This modification increases the potency of 2'-TFA-NH-dC by making it more difficult for enzymes in cells to break down the drug. The compound can be used as a monophosphate or diphosphate, and is synthesized from 2'-deoxyadenosine 5'-phosphoramidite and 1,2,4-triazole in water.</p>
    Formula:C11H13F3N4O5
    Purezza:Min. 95%
    Peso molecolare:338.24 g/mol

    Ref: 3D-NT57540

    100mg
    303,00€
    250mg
    453,00€
    500mg
    651,00€
  • 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution


    <p>2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution is a high purity synthetic compound that is used as an activator for the synthesis of DNA, RNA, and phosphoramidites. The product is in the form of a white to off-white solid and has high quality with purity of &gt;99%. 2'-Deoxy-2'-fluoroadenosine-5'-triphosphate sodium salt - 100mM aqueous solution can be used in antiviral, anticancer, and antideoxyribonucleoside therapy. It inhibits viral replication by inhibiting reverse transcriptase activity in HIV and other retroviruses. It also inhibits tumor growth by interfering with DNA synthesis.</p>
    Formula:C10H15FNO12P3·xNa
    Purezza:Min. 95%
    Peso molecolare:453.15 g/mol

    Ref: 3D-ND13493

    5mg
    394,00€
    10mg
    547,00€
    25mg
    1.096,00€
    2500µg
    303,00€
  • o-Methoxytopolin riboside

    CAS:
    <p>o-Methoxytopolin Riboside is a novel phosphoramidite that can be used for the synthesis of ribonucleotides and deoxyribonucleosides. This product has antiviral and anticancer properties, as well as the ability to inhibit tumor growth by inducing apoptosis in cancer cells. It is synthesized from the natural compound o-methoxytyrosine by the addition of a phosphate group to the 3-position. The phosphate group is then modified to produce monophosphate or diphosphate forms. OMTPR has been shown to have anti-inflammatory properties and has been found to reduce inflammation in mice with colitis.</p>
    Formula:C18H21N5O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:387.39 g/mol

    Ref: 3D-NM30298

    1g
    996,00€
    1mg
    997,00€
    100mg
    320,00€
    250mg
    457,00€
    500mg
    639,00€
  • 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine

    CAS:
    <p>9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine is a modified nucleoside that is used as an antiviral and anticancer agent. It acts as an activator for the synthesis of DNA, RNA, and protein. 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine also inhibits the growth of cancer cells by interfering with the division process. This drug is synthesized from 9-(5'-deoxy-5'-iodo-b-D-ribofuranosyl) -2,6 difluoro adenine (diFdA). The Ribonucleosides are then prepared in a similar manner to other nucleosides by using phosphoramidites. The product is then purified using HPLC.</p>
    Formula:C10H11F2N5O3
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:287.23 g/mol

    Ref: 3D-ND09526

    10mg
    182,00€
    25mg
    291,00€
    50mg
    410,00€
    100mg
    607,00€
    250mg
    920,00€
  • Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt

    CAS:
    <p>Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.</p>
    Formula:C20H26N7O10P·NH3
    Purezza:Min. 95%
    Peso molecolare:572.47 g/mol

    Ref: 3D-NT08058

    1mg
    303,00€
    2mg
    394,00€
    5mg
    673,00€
    10mg
    837,00€
  • Thymidine-5'-diphosphate-6-deoxy-D-allose


    <p>Thymidine-5'-diphosphate-6-deoxy-D-allose (TDP) is a high quality monophosphorylated nucleoside that is used as an activator, anticancer, and antiviral agent. TDP has been modified to improve the efficacy and safety of cancer treatments by enhancing the cytotoxicity of chemotherapeutics. TDP also has antiviral properties and can be used in the treatment of HIV infections by inhibiting viral replication.</p>
    Purezza:Min. 95%

    Ref: 3D-NT29841

    5mg
    1.628,00€
    10mg
    2.867,00€
  • 2',3'-Dideoxy-N2-isobutyrylguanosine


    <p>2',3'-Dideoxy-N2-isobutyrylguanosine is a monophosphate that inhibits viral replication by competing with the natural substrate, diphosphate. It is synthesized in high purity and quality by our company. 2',3'-Dideoxy-N2-isobutyrylguanosine has been used as an antiviral agent to inhibit the hepatitis B virus. This product is also of interest for its potential use in cancer treatment.</p>
    Formula:C14H19N5O4
    Purezza:Min. 95%
    Peso molecolare:321.34 g/mol

    Ref: 3D-ND08543

    25mg
    303,00€
    50mg
    414,00€
    100mg
    664,00€
  • 5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite

    CAS:
    <p>5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite is a high purity, novel, modified, antiviral and anticancer nucleotide. It is an analog of thymidine which has the methyl group at the 5' position replaced with a 5' amino group. This modification prevents conversion of the nucleoside to thymine and therefore inhibits DNA synthesis. The phosphoramidite is used as a building block for oligonucleotides in chemical synthesis. The phosphoramidite has shown antiviral activity against HIV by preventing reverse transcription of viral RNA into DNA. It also has been tested for its anticancer effects on human cells in vitro by inhibiting DNA synthesis and inducing apoptosis in cancer cells.</p>
    Formula:C39H48N5O6P
    Purezza:Min. 95%
    Peso molecolare:713.8 g/mol

    Ref: 3D-PA09015

    1g
    2.562,00€
    2g
    3.586,00€
  • 2',3'-Dideoxy-2',3'-didehydroinosine

    CAS:
    <p>2',3'-Dideoxy-2',3'-didehydroinosine is a synthetic pyrimidine compound that has been shown to inhibit tumor growth in animal models. It is used to prepare 2',3'-dideoxy-2',3'-didehydroinosine-5'-triphosphate, which inhibits the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase. This inhibition leads to cell death by inducing crosslinkers and inhibiting polymerase chain reaction. 2',3'-Dideoxy-2',3'-didehydroinosine can be synthesized from hydrochloric acid and carbonyl compounds such as glyoxal, acetaldehyde, or benzaldehyde.<br>2',3'-Dideoxy-2',3'-didehydroinosine is an important part of phylogenetic tree analysis because it provides information about evolutionary relationships between bacteria.</p>
    Formula:C10H10N4O3
    Purezza:Min. 95 Area-%
    Colore e forma:White Powder
    Peso molecolare:234.21 g/mol

    Ref: 3D-ND29820

    1g
    2.681,00€
    2g
    4.884,00€
    100mg
    489,00€
    250mg
    928,00€
    500mg
    1.568,00€
  • 3-Deazaguanosine

    CAS:
    <p>3-Deazaguanosine is a nucleotide that is found in uridine, which is present in the nucleic acids of all cells. It has been shown to be cytotoxic to colorectal adenocarcinoma and carcinoma cell lines, and this cytotoxicity may be due to its ability to inhibit energy metabolism. 3-Deazaguanosine has also been shown to significantly inhibit viral replication, including HIV and herpes simplex virus type 1. It binds with high affinity to monoclonal antibodies that are specific for nucleotide levels. 3-Deazaguanosine inhibits tissue culture enzyme activity and can cause significant changes in adenine nucleotide levels in cell culture.</p>
    Formula:C11H14N4O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:282.25 g/mol

    Ref: 3D-ND30048

    1g
    2.013,00€
    2g
    3.172,00€
    250mg
    930,00€
    500mg
    1.378,00€
  • Cyclic diguanosine monophosphate

    CAS:
    <p>Cyclic diguanosine monophosphate (c-di-GMP) is a nucleotide that is involved in bacterial cell signaling. It has been shown to be essential for the formation of bacterial biofilms and plays an important role in the development of infectious diseases. c-di-GMP is synthesized from guanosine triphosphate through a series of enzymatic reactions and then hydrolyzed by cyclic diguanosine monophosphatase, which leads to its termination as a second messenger. c-di-GMP interacts with proteins that regulate the expression of genes involved in biofilm formation, motility, and virulence. The synthesis and hydrolysis of c-di-GMP are regulated by multiple enzymes, including protein phosphatases, that control cellular physiology such as biofilm formation.</p>
    Formula:C20H24N10O14P2
    Purezza:Min. 95%
    Peso molecolare:690.41 g/mol

    Ref: 3D-NC46014

    1mg
    449,00€
    2mg
    731,00€
    5mg
    1.503,00€
    10mg
    2.635,00€
  • 5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1)

    CAS:
    <p>5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1) is a novel monophosphate nucleoside that has been synthesized and evaluated in vitro as an anticancer agent. It inhibits the proliferation of various human tumor cell lines, including breast cancer cells. This compound is also active against HIV-1 virus but not against other viruses tested. 5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1), like other nucleosides, can be modified to suit particular needs and then used for therapeutic purposes.</p>
    Formula:C31H33N2O9P
    Purezza:Min. 95%
    Peso molecolare:608.58 g/mol

    Ref: 3D-NT158343

    1g
    2.135,00€
  • 3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine


    <p>3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is a novel nucleoside with antiviral and anticancer properties. It has been shown to inhibit the growth of human tumor cells in culture and induce apoptosis, as well as inhibit viral replication. 3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is an analogue of uridine, which can be used for the synthesis of DNA or RNA. The phosphate group is attached to the 3' carbon on the sugar moiety. This nucleoside has been modified from a natural ribonucleoside by substitution of a tertiary butylphenylsilyl group at the 2' position with an o-methyl group.<br>3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is supplied as a white powder with purity greater than 99</p>
    Purezza:Min. 95%

    Ref: 3D-NB64783

    10g
    3.050,00€
  • 2',3'-Di-O-methylguanosine


    <p>2',3'-Di-O-methylguanosine is a nucleoside, which is a chemical compound composed of a nitrogenous base, a five-carbon sugar, and one phosphate group. It is an analog of guanosine that has been modified by replacing the 2' hydroxyl group with a methyl group. This modification prevents the phosphorylation of the monophosphate form to the diphosphate form. This modification also makes 2',3'-Di-O-methylguanosine an activator of DNA polymerase and RNA polymerase. The novel features of this compound make it an excellent candidate for anticancer and antiviral treatments.</p>
    Purezza:Min. 95%

    Ref: 3D-ND35419

    1g
    2.440,00€
  • 2-[2-(2-Naphthalenyl)ethoxy]adenosine

    CAS:
    2-[2-(2-Naphthalenyl)ethoxy]adenosine is a structural determinant that belongs to the class of adenosine derivatives. It is an antagonist of adenosine receptors, binding to the A1 receptor with high affinity and blocking the effects of adenosine. 2-[2-(2-Naphthalenyl)ethoxy]adenosine has been shown to have a high affinity for benzyl and thioether groups in its structure, which are important for binding to the A1 receptor. This compound has been used in assays to determine the binding of other compounds with adenosine receptors. 2-[2-(2-Naphthalenyl)ethoxy]adenosine has also been shown as a radioligand for competitive binding studies with human brain membranes.
    Formula:C22H23N5O5
    Purezza:Min. 95%
    Peso molecolare:437.45 g/mol

    Ref: 3D-NN16559

    25mg
    336,00€
    50mg
    456,00€
    100mg
    731,00€
    250mg
    1.254,00€
    500mg
    2.141,00€
  • 3'-O-DMT-thymidine

    CAS:
    <p>3'-O-DMT-thymidine is a nucleoside analogue that is synthesized from thymidine. It has been shown to bind to the proviral dna of HIV and inhibit viral replication when present in a complex with the other nucleosides. 3'-O-DMT-thymidine is also stable at high temperatures and binds to carboxamide groups on proteins. This compound has been shown to be effective as a binder for surfaces and membranes, which may be due to its ability to form stable complexes with terminal phosphates. The stability of these complexes can be influenced by the presence of denaturants such as temperature, pH, or ionic strength parameters. 3'-O-DMT-thymidine also forms stable complexes with linkers that are sensitive to thermal denaturation.</p>
    Formula:C31H32N2O7
    Purezza:Min. 95%
    Peso molecolare:544.6 g/mol

    Ref: 3D-ND06918

    1g
    574,00€
    2g
    838,00€
    5g
    1.227,00€
    250mg
    325,00€
    500mg
    470,00€
  • 6-O-Benzyl-2'-deoxyguanosine

    CAS:
    <p>6-O-Benzyl-2'-deoxyguanosine is a synthetic nucleoside analog that inhibits the synthesis of DNA. It is used in animal studies as a pancreatic carcinogen, and has been shown to inhibit tumor growth in mice. This drug specifically binds to DNA at the O6 position of guanine and methylates the adjacent cytosine residue, thereby preventing synthesis of DNA. 6-O-Benzyl-2'-deoxyguanosine also inhibits the activity of an enzyme called methyltransferase, which converts S-adenosylmethionine into S-adenosylhomocysteine, an intermediate in one of the pathways that produce methionine from homocysteine. This inhibition leads to an accumulation of methionine and its metabolites, including homocysteine and cystathione beta synthase, which can cause cell death.</p>
    Formula:C17H19N5O4
    Purezza:Min. 95%
    Peso molecolare:357.36 g/mol

    Ref: 3D-NB16627

    5mg
    486,00€
    10mg
    729,00€
  • N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite

    CAS:
    <p>N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite is a novel nucleoside. It is a monophosphate and cytidine analog that has been shown to be effective in the treatment of cancer. N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite also inhibits viral replication by preventing the synthesis of DNA and RNA. This drug can be used as an activator for synthesis of modified oligonucleotides.</p>
    Formula:C41H50N5O8P
    Purezza:Min. 95%
    Peso molecolare:771.84 g/mol

    Ref: 3D-PA08885

    1g
    669,00€
    100mg
    303,00€
    250mg
    354,00€
    500mg
    497,00€
  • N6,5'-O-Dibenzoyl-2'-deoxy-adenosine


    <p>N6,5'-O-Dibenzoyl-2'-deoxy-adenosine is a monophosphate nucleoside that is used in the synthesis of DNA. It is synthesized from 2'-deoxyadenosine, which is an antiviral agent against influenza virus and anticancer agent. N6,5'-O-Dibenzoyl-2'-deoxy-adenosine has been shown to be a potent activator of the polymerase chain reaction with high purity and novel properties.</p>
    Formula:C24H21N5O5
    Purezza:Min. 95%
    Peso molecolare:475.45 g/mol

    Ref: 3D-ND06914

    1g
    2.440,00€
  • L-Ribose NAD


    <p>L-Ribose NAD is a nucleoside that belongs to the group of ribonucleosides. It is a novel modified monophosphate and diphosphate nucleotide. L-Ribose NAD has antiviral, anticancer, and immunomodulatory activities. L-Ribose NAD can activate cells with DNA damage by inhibiting the synthesis of deoxyribonucleosides, which are needed for DNA repair. This product has a high purity level and high quality.</p>
    Purezza:Min. 95%
    Peso molecolare:663 g/mol

    Ref: 3D-NL30093

    1g
    2.440,00€
  • N2-DMF-2'-O-methylguanosine

    CAS:
    <p>N2-DMF-2'-O-methylguanosine is a nucleoside that is used as an antiviral agent and anticancer drug. It has been shown to inhibit the growth of human cancer cells in vitro and in vivo. N2-DMF-2'-O-methylguanosine has also been shown to inhibit viral replication by inhibiting DNA synthesis. This nucleoside is a novel compound that can be synthesized using phosphoramidites, which are high quality and yield high purity products.</p>
    Formula:C14H20N6O5
    Purezza:Min. 95%
    Peso molecolare:352.35 g/mol

    Ref: 3D-ND08423

    1g
    526,00€
    2g
    883,00€
    250mg
    304,00€
    500mg
    356,00€
  • 5'-O-DMT-2'-O-hexylaminoadenosine


    <p>5'-O-DMT-2'-O-hexylaminoadenosine is a modified nucleoside that has antiviral activity. It is the monophosphate form of 5'-O-DMT-2'-O-hexylaminoadenosine, and it is used in the synthesis of phosphoramidites for DNA and RNA. This nucleoside is also an activator for novel antiviral drugs.</p>
    Formula:C37H44N6O6
    Purezza:Min. 95%
    Peso molecolare:668.8 g/mol

    Ref: 3D-ND08516

    1g
    1.067,00€
    100mg
    303,00€
    250mg
    416,00€
    500mg
    669,00€
  • 5-[(Methylamino)methyl]uridine

    CAS:
    <p>5-[(Methylamino)methyl]uridine is a proton-containing analog of uridine. It is an epigenetic modifier that has been shown to have conformational properties that are similar to those of uridine. 5-[(Methylamino)methyl]uridine has been shown to modify the glycosidic bond and ring structures, which are important for its function in protein synthesis. The compound can also be found as a chemical structure in the ribosomal subunit, where it is involved in protein synthesis and translation. 5-[(Methylamino)methyl]uridine has shown potential as a therapeutic agent for cancer treatment due to its ability to inhibit the expression of oncogenes in cells and induce programmed cell death (apoptosis).</p>
    Formula:C11H17N3O6
    Purezza:Min. 95%
    Peso molecolare:287.27 g/mol

    Ref: 3D-NM159410

    1g
    4.541,00€
    2g
    5.280,00€
  • 2-Amino-4-methoxypyrimidine

    CAS:
    <p>2-Amino-4-methoxypyrimidine is an organic compound that can be synthesized from 2-amino-4-chloropyrimidine. It is a colorless, water soluble solid with a melting point of 166°C. The UV spectrum of 2-amino-4-methoxypyrimidine exhibits absorption maxima at 240 nm and 280 nm. When 2-amino-4-methoxypyrimidine is exposed to UV light, it emits fluorescent light at 360 nm. The IR spectrum exhibits absorption bands at 3200 cm−1, 1650 cm−1, and 1530 cm−1. Hydrogen bonding interactions occur between the methoxy group and the protonated amine group in the molecule's structure. The yield of this reaction was found to be 65% by GC analysis. This reaction occurs in two steps: first, the imino group reacts with n hexane to form an iminium ion</p>
    Purezza:Min. 95%

    Ref: 3D-NA44306

    1g
    403,00€
    500mg
    300,00€
  • 2'-Deoxy-5'-O-DMT-adenosine

    CAS:
    <p>2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.</p>
    Formula:C31H31N5O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:553.61 g/mol

    Ref: 3D-ND57357

    1g
    341,00€
    2g
    486,00€
    5g
    921,00€
    10g
    1.627,00€
    500mg
    233,00€
  • [1',2',3',4',5'-13C5]-4-Thiothymidine


    <p>[1',2',3',4',5'-13C5]-4-Thiothymidine is an antiviral, anticancer, and activator of DNA synthesis. It is a monophosphate analog of thymidine that has been modified to include a radioactive isotope. [1',2',3',4',5'-13C5]-4-Thiothymidine binds to the active site of the enzyme ribonucleotide reductase which is responsible for the production of DNA from RNA. The incorporation of this radioactively labeled analog into DNA prevents its degradation by nucleases and allows for the detection and quantification of DNA synthesis via autoradiography.</p>
    Purezza:Min. 95%

    Ref: 3D-NT35287

    1g
    2.440,00€
  • 2'-Deoxy-1,N6-dimethyladenosine


    <p>2'-Deoxy-1,N6-dimethyladenosine is a nucleoside that is used for the synthesis of DNA and RNA. It has antiviral activity against HIV and herpes simplex virus type 1 (HSV-1). 2'-Deoxy-1,N6-dimethyladenosine binds to viral DNA and inhibits viral replication by preventing the viral DNA from being replicated. It also inhibits the synthesis of viral proteins. This nucleoside is synthesized in a high purity and quality, which makes it an excellent starting material for use in the synthesis of other nucleosides or phosphoramidites.</p>
    Purezza:Min. 95%

    Ref: 3D-ND159725

    100mg
    3.660,00€
  • 2'-O-(2-Ethoxy-2-oxoethyl)adenosine


    <p>2'-O-(2-Ethoxy-2-oxoethyl)adenosine is a nucleoside that is a modified version of adenosine. It is phosphorylated to form 2'-O-(2-ethoxy-2-oxoethyl)adenosin-5'-yl monophosphate, which has antiviral activity and is used as an antiviral agent in the treatment of herpes simplex virus. The chemical structure of this nucleoside is novel, and it binds to the ribonucleotide reductase enzyme to prevent the synthesis of DNA and RNA. This drug also has anticancer properties, but it is not active against bacterial infections.</p>
    Purezza:Min. 95%

    Ref: 3D-NE158848

    250mg
    304,00€
    500mg
    336,00€
  • 2-Chloropyrimidine-4-carboxamide

    CAS:
    <p>2-Chloropyrimidine-4-carboxamide is an activator that is a novel chemical entity of deoxyribonucleosides, phosphoramidites, ribonuclesides, and antiviral nucleosides. It has been shown to have high purity and quality. 2-Chloropyrimidine-4-carboxamide has been used in the synthesis of oligodeoxynucleotides for antiviral activity.</p>
    Formula:C5H4ClN3O
    Purezza:Min. 95%
    Peso molecolare:157.56 g/mol

    Ref: 3D-NC57418

    1g
    478,00€
    2g
    725,00€
    500mg
    300,00€
  • AFB-guanine

    CAS:
    <p>AFB-guanine is a purine nucleoside that has been found to be an intermediate in the conversion of adenosine to inosine. The toxicity of AFB-guanine was studied using the model system of rat liver microsomes and human liver. It was observed that AFB-guanine is metabolized by glycosylases, which act on purines and pyrimidines. The glycosylase activity was inhibited by dicoumarol, which results in a decrease in the amount of AFB-guanine that is converted to adenosine triphosphate (ATP). The study also showed that histological analysis revealed degenerative diseases and cancer in mice fed with AFB-guanine, suggesting that this compound may be carcinogenic.</p>
    Formula:C22H17N5O8
    Purezza:Min. 95%
    Peso molecolare:479.4 g/mol

    Ref: 3D-NA17231

    1mg
    2.141,00€
    2mg
    3.892,00€
  • 5-Methylcytidine HCl


    <p>5-Methylcytidine HCl is a novel antiviral and anticancer agent. It possesses two important properties: it is an activator of the enzyme ribonucleotide reductase, which regulates DNA synthesis and repair; and it inhibits the activity of DNA polymerases. It is also chemically modified to allow its use in phosphoramidite synthesis. 5-Methylcytidine HCl has been shown to cause apoptosis in cancer cells, as well as inhibit the growth of bacteria.</p>
    Formula:C10H15N3O5·HCl
    Purezza:Min. 95%
    Peso molecolare:293.7 g/mol

    Ref: 3D-NM08573

    1g
    669,00€
    250mg
    304,00€
    500mg
    416,00€
  • 2-[2-(4-Fluorophenyl)ethoxy]adenosine

    CAS:
    <p>2-[2-(4-Fluorophenyl)ethoxy]adenosine is a hydrogen-bonded, hydrated, switchable molecule. The techniques used to characterize this compound include vibrational spectroscopy and Raman spectroscopy. 2-[2-(4-Fluorophenyl)ethoxy]adenosine has been shown to have high salt and thermal stability. It has also been shown to undergo conformational changes in the presence of chemists.</p>
    Formula:C18H20FN5O5
    Purezza:Min. 95%
    Peso molecolare:405.38 g/mol

    Ref: 3D-NF16548

    1g
    1.920,00€
    50mg
    303,00€
    100mg
    403,00€
    250mg
    651,00€
    500mg
    1.051,00€