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Nucleosidi

Nucleosidi

I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.

Trovati 3569 prodotti di "Nucleosidi"

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  • 3',5'-O-(Di-tert-butylsilanediyl)uridine

    CAS:

    3',5'-O-(Di-tert-butylsilanediyl)uridine is a novel antiviral agent that is synthesized from uridine and has been shown to be effective against herpes simplex virus. This compound was also shown in vitro to inhibit the replication of human immunodeficiency virus type 1 (HIV-1). 3',5'-O-(Di-tert-butylsilanediyl)uridine binds to single stranded DNA, preventing the synthesis of DNA by the viral enzyme reverse transcriptase. It also inhibits the production of viral proteins by binding to viral RNA polymerase. This drug may also have anticancer activity due to its ability to inhibit ribonucleotide reductase, an enzyme required for DNA synthesis.

    Purezza:Min. 95%

    Ref: 3D-ND72055

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  • 5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium, 100mM aqueous solution


    5-Aminoallyl 2'-deoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution is a novel modified nucleoside that can be activated to the corresponding phosphoramidite.

    Formula:C12H17N4O13P3•Li4
    Purezza:Min. 95%
    Colore e forma:Clear Liquid
    Peso molecolare:545.97 g/mol

    Ref: 3D-NA32075

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  • 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt


    Please enquire for more information about 3'-O-Aminoacetoxythymidine 5'-O-triphosphate triethylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C13H22N3O14P3•(C6H15N)x
    Purezza:Min. 99 Area-%
    Colore e forma:Powder
    Peso molecolare:537.25 g/mol

    Ref: 3D-NA180287

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  • 5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzylidene]-pyrimidine-2,4,6-trione


    Ribonuclease is an enzyme that cleaves the phosphodiester backbone of ribonucleotide to produce a 5'-phosphate and a 2'-deoxyribonucleoside. Ribonuclease is an activator that activates the synthesis of ribonucleotides, deoxyribonesucleotides and nucleosides. Ribonuclease has antiviral properties which may be due to its ability to inhibit DNA polymerase by catalyzing the hydrolysis of the 2'-deoxyribose-5'-phosphate bond in DNA. Ribonuclease has also been shown to have anticancer activity, which may be due to its ability to inhibit protein synthesis.

    Purezza:Min. 95%

    Ref: 3D-NT44284

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  • Isowyosine

    CAS:

    Isowyosine is a protein that catalyzes the synthesis of purines, which are essential for DNA synthesis and repair. Isowyosine is found in mammalian cells, where it has been observed to play a role in the translation of messenger RNA (mRNA). Isowyosine also plays a role in the synthesis of viral proteins and viral replication. It has been shown to be active against various viruses, including herpes simplex virus and influenza virus. Isowyosine may also have anti-cancer properties due to its ability to inhibit tumor growth.

    Formula:C14H17N5O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:335.32 g/mol

    Ref: 3D-NI159495

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  • 2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å


    2'-Deoxy-3'-O-DMT-N2-iBu-guanosine--succinyl-CPG 1000 Å is a modified nucleoside that is synthesized from 2'-deoxyribonucleosides and succinic anhydride. It has antiviral, anticancer, and antimalarial activities. It can also be used to modify DNA sequences. This product is a novel phosphoramidite monomer with high purity.

    Purezza:Min. 95%

    Ref: 3D-ND11609

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  • N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5-iodocytidine


    N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5-iodocytidine is an antiviral drug that inhibits viral DNA synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. It is a nucleoside analog that is used for the treatment of cancer and for the prevention of AIDS. N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-5 -iodocytidine is synthesized in high purity, with a purity level of > 98%. This product can be used as an activator or ligand in phosphoramidite synthesis.
    Formula:C22H30IN3O5Si
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:571.48 g/mol

    Ref: 3D-NB09206

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  • 2',3'-Dideoxy-2',2'-difluorocytidine

    CAS:

    2',3'-Dideoxy-2',2'-difluorocytidine is a monophosphate derivative of the antiviral and anticancer drug 2',3'-dideoxycytidine. It is an activator of DNA synthesis, nucleosides, and nucleotides. It is also a phosphoramidite for the synthesis of oligonucleotides and modified ribonucleosides. 2',3'-Dideoxy-2',2'-difluorocytidine has CAS number 124708-94-7. It is available in high purity and quality, which makes this product suitable for research purposes.

    Purezza:Min. 95%

    Ref: 3D-ND158370

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  • 3'-Deoxy-L-thymidine

    CAS:

    3'-Deoxy-L-thymidine is a nucleoside analog that inhibits HIV replication by interfering with the synthesis of viral DNA. The drug binds to the enzyme thymidine phosphorylase, which converts thymidine into deoxyuridine monophosphate, and prevents conversion of deoxyuridine to deoxythymidine monophosphate. This leads to inhibition of both DNA synthesis and the production of RNA. 3'-Deoxy-L-thymidine has dose-limiting toxicity at high doses and is not active against other viruses such as herpes simplex virus or cytomegalovirus. It is metabolized in the liver by enzymes such as 5-fluorocytosine, which converts it into its active form, 5-fluorouracil.

    Formula:C10H14N2O4
    Purezza:Min. 95%
    Peso molecolare:226.23 g/mol

    Ref: 3D-ND02766

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  • 2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer), lithium salt


    2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer) is a synthetic nucleoside that acts as an antiviral, anticancer and antineoplastic agent. It has been shown to inhibit the replication of DNA and RNA by inhibiting the activity of ribonucleoides. 2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer) can be used in combination with other antiviral agents such as acyclovir or valacyclovir to treat herpes simplex virus type 1 infections. The drug is also effective against HIV, with a potency similar to that of zidovudine. It has been shown to be active in the treatment of leukemia, lymphoma, Hodgkin's disease and some solid tumors.
    Purezza:Min. 95%

    Ref: 3D-ND32051

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  • N6-Benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å


    N6-benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å is a novel nucleoside with antiviral activity. It is synthesized by the condensation of 2'-deoxyadenosine monophosphate and 3'-Q linker CPG 1000 Å. The molecular weight of N6-benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å is 878.36 g/mol, and its CAS number is 628674-06-4. This substance has antiviral activity against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2). N6-benzoyl-2'-deoxy-5'-O-DMT adenosine can be used as an anticancer drug because it inhibits the growth

    Purezza:Min. 95%

    Ref: 3D-NB11617

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  • 2'-Deoxy-5'-O-DMT-adenosine

    CAS:

    2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.

    Formula:C31H31N5O5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:553.61 g/mol

    Ref: 3D-ND57357

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  • 3',5'-Di-O-acetyl-2'-deoxyguanosine

    CAS:

    3',5'-Di-O-acetyl-2'-deoxyguanosine is a nucleoside that is activated by hypochlorous acid to form a reactive intermediate, which can then react with other molecules. 3',5'-Di-O-acetyl-2'-deoxyguanosine has been shown to be selectively cytotoxic to human tumor cells and may be used as a radiosensitizer for cancer treatment. The reaction products of this compound include hypochlorite and hydrogen peroxide, which are strong oxidizing agents that cause tissue injury. This compound is also an effective reagent for the detection of myeloperoxidase in plasma samples.

    Formula:C14H17N5O6
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:351.32 g/mol

    Ref: 3D-ND04500

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  • 4-(2-Thienyl)-2-pyrimidinethiol

    CAS:

    Ribonucleosides are nucleosides that contain a ribose sugar. They are important in the synthesis of DNA and RNA. Ribonuclesides are nucleosides containing a ribose sugar with a phosphate group on the 5' carbon. The phosphate is attached to the 4' carbon on the sugar, instead of the 3' carbon as in deoxyribonucleosides. Ribonucleosides are important in the synthesis of DNA and RNA. Ribonucleotides are nucleotides that contain a ribose sugar with a phosphate group on the 5’ carbon. The phosphate is attached to the 4’ carbon on the sugar, instead of the 3’ carbon as in deoxyribonucleotides. Ribonucleotides are important in the synthesis of DNA and RNA.
    In addition, Ribonucleside can be used as antiviral agent for HIV-1 through inhibition at viral reverse transcriptase (RT) step by competing

    Formula:C8H6N2S2
    Purezza:Min. 95%
    Peso molecolare:194.28 g/mol

    Ref: 3D-NT57413

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  • Uridylyl-3'-5'-cytidine ammonium salt


    Uridylyl-3'-5'-cytidine ammonium salt is a monophosphate of cytidine. It is an antiviral agent that inhibits the replication of human immunodeficiency virus type 1 (HIV-1). Uridylyl-3'-5'-cytidine ammonium salt is synthesized by the reaction of uridyl 3'-5' -adenosine monophosphate with cytidine. This compound has been shown to be effective in inhibiting the proliferation of cancer cells. Uridylyl-3'-5'-cytidine ammonium salt has shown activity against a variety of cancers, including breast, lung, and colon cancers.

    Formula:C18H27N6O13P
    Purezza:Min. 95%
    Peso molecolare:566.41 g/mol

    Ref: 3D-NU46048

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  • N6-Methyladenosine-5'-triphosphate sodium salt - 10 mM aqueous solution

    CAS:

    Modulator of P2Y receptors

    Formula:C11H18N5O13P3
    Purezza:Min. 95%
    Peso molecolare:521.21 g/mol

    Ref: 3D-NM71656

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  • 2’-Deoxy-2-methyladenosine

    CAS:

    2’-Deoxy-2-methyladenosine is a nucleoside that is chemically synthesized by the phosphorylation of 2,6-diaminopurine. It has been shown to be an effective activator of RNA polymerase and it also has anticancer properties. 2’-Deoxy-2-methyladenosine can be used as a substitute for thymidine in DNA synthesis. This nucleoside has also been shown to inhibit bacterial growth in culture by inhibiting DNA synthesis and protein synthesis. It is a modified nucleoside that can be used for the synthesis of DNA, RNA, or ribonucleic acids. The CAS number for this compound is 110952-90-4.

    Purezza:Min. 95%

    Ref: 3D-ND163169

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  • 8-Oxo-N2-isobutyryl-2-deoxyguanosine

    CAS:

    8-Oxo-N2-isobutyryl-2-deoxyguanosine is a modified synthetic nucleoside.  It finds applications in understanding mutagenesis and DNA repair mechanisms.

    Formula:C14H19N5O6
    Purezza:Min. 95%
    Peso molecolare:353.33 g/mol

    Ref: 3D-LFA85976

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  • 5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite

    CAS:
    5'-O-DMT-2'-O,4'-C-methylene-5-methyluridine 3'-CE-phosphoramidite is a high purity, novel DNA monophosphate that is synthesized from 2',4'-diaminotoluene and 5'-O-dimethoxytritylthymidine. It has antiviral and anticancer properties and has shown to be an activator of RNA polymerase II in vitro. This product is used in many applications such as the synthesis of oligonucleotide probes for DNA sequencing, the synthesis of RNA for gene expression studies, and for the production of oligonucleotides for therapeutic purposes.
    Formula:C41H49N4O9P
    Purezza:Min. 95%
    Peso molecolare:772.82 g/mol

    Ref: 3D-ND163164

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  • 3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine


    3'-O-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorouridine is a novel, activator, ribonucleosides, deoxyribonucleosides, diphosphate, phosphoramidites, modified nucleosides. It can be used as an anticancer and antiviral agent.

    Formula:C32H31FN2O8
    Purezza:Min. 95%
    Peso molecolare:590.6 g/mol

    Ref: 3D-NA08460

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  • 3',5'-Diamino-3',5'-dideoxyadenosine

    CAS:

    3',5'-Diamino-3',5'-dideoxyadenosine (3,5-ddA) is a nucleoside that has been shown to be an efficient inhibitor of HIV replication in vitro. It has been used for the treatment of AIDS, but it is not yet approved for this use. 3,5-ddA inhibits the conversion of dATP to dTTP and prevents DNA synthesis by blocking the enzyme ribonucleotide reductase. The drug can be synthesized with high efficiency by using a modified nucleoside amidite approach.

    Formula:C10H15N7O2
    Purezza:Min. 95%
    Peso molecolare:265.28 g/mol

    Ref: 3D-ND08739

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  • 5-Azauridine

    CAS:

    5-Azauridine is a nucleoside that is synthesized from uridine. It inhibits protein synthesis by inhibiting the enzyme orotate phosphoribosyltransferase. This enzyme converts orotic acid to orotidine 5′-monophosphate, which is a precursor for the synthesis of pyrimidines and purines. 5-Azauridine has been shown to have an inhibitory effect on leukemia cells in tissue culture and also has been shown to inhibit leukemic mice with an efficacy of 50%. This drug may be useful for the treatment of solid tumours as it inhibits protein synthesis.

    Formula:C8H11N3O6
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:245.19 g/mol

    Ref: 3D-NA145615

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  • 6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one

    CAS:
    6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is a novel nucleoside analog that has been modified to contain an antiviral agent. It is phosphorylated at the 2' position to form a monophosphate. This compound is a potent inhibitor of HIV reverse transcriptase and human DNA polymerases α and β. The structure of this compound contains a furano ring fused with the pyrimidine moiety, which is substituted with methyl groups on C6 and C3 positions. The CAS number for 6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is 383897−60−7.
    Formula:C12H14N2O5
    Purezza:Min. 95%
    Peso molecolare:266.25 g/mol

    Ref: 3D-IQA89760

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  • 5-Isopropyl-2'-deoxyuridine

    CAS:

    5-Isopropyl-2'-deoxyuridine is a nucleoside analog that is used in the treatment of inflammatory bowel disease. It has been shown to be effective in the treatment of Crohn's disease, ulcerative colitis, and indeterminate colitis. 5-Isopropyl-2'-deoxyuridine inhibits bacterial growth by inhibiting RNA synthesis, which leads to cell death. This drug also inhibits the production of inflammatory mediators such as prostaglandins and leukotrienes that are released from cells infected with bacteria. 5-Isopropyl-2'-deoxyuridine is converted into an active form by hydrolysis or oxidation followed by phosphorylation. This drug binds to the 5' end of bacterial DNA and prevents the formation of hydrogen bonds between adjacent bases, causing strand breakage.

    Formula:C12H18N2O5
    Purezza:Min. 95%
    Peso molecolare:270.28 g/mol

    Ref: 3D-NI16765

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  • 2',5'-Dideoxyinosine

    CAS:

    2',5'-Dideoxyinosine is a nucleoside that can be used as an antiviral or anticancer agent. It is synthesized from the natural nucleoside inosine by phosphorylation of the hydroxyl group on position 5 of the sugar ring and replacement of the hydroxyl group on position 2 with a deoxyribose. The resulting product has a higher potency than the natural form, and is more stable to enzymatic hydrolysis. 2',5'-Dideoxyinosine has been shown to inhibit DNA polymerase in vitro, and also inhibits RNA synthesis, leading to cell death. In addition, it has been shown to be active against leukemia cells as well as breast cancer cells in vivo.

    Formula:C10H12N4O3
    Purezza:Min. 95%
    Peso molecolare:236.23 g/mol

    Ref: 3D-ND08407

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  • 5-Methyl-2',3'-stannyluridine


    5-Methyl-2',3'-stannyluridine is a nucleoside analog that is a potent inhibitor of viral replication and can be used for the treatment of HIV. It has been shown to inhibit the activity of RNA polymerase, thereby preventing transcription and replication. 5-Methyl-2',3'-stannyluridine also inhibits DNA synthesis by inhibiting the activity of DNA polymerase. This drug also acts as an antitumor agent and has been shown to inhibit tumor growth in animal models. The high purity of this drug makes it suitable for use in pharmaceutical applications.
    5-Methyl-2',3'-stannyluridine is a modified nucleoside that has been modified with a stannyl group at the 2' position on the sugar moiety and an allyl group at the 3' position on the sugar moiety. The phosphoramidites are synthesized from 5-methyl-2',3'-stannyl

    Purezza:Min. 95%

    Ref: 3D-NM158812

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  • Linoleoyl coenzyme A

    CAS:

    Linoleoyl coenzyme A (LCA) is a fatty acid that is a component of the cell membrane. LCA is synthesized from linoleic acid and coenzyme A in the mitochondria. In humans, LCA is an important component of the mitochondrial protein. The production of this enzyme can be enhanced by dietary supplementation with linoleic acid. Linoleoyl coenzyme A has been used as a model system to study energy metabolism in mitochondria. It has been shown to be involved in carthamus tinctorius, human mitochondrial, rat liver microsomes, and dietary models. LCAs have also been used as analytical methods for measuring the amount of fatty acids within cells or tissues.

    Formula:C39H66N7O17P3S
    Purezza:Min. 95%
    Peso molecolare:1,029.97 g/mol

    Ref: 3D-NL47198

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  • 2'-TFA-NH-dG

    CAS:

    2'-TFA-NH-dG is a novel nucleoside analog that is used as an antiviral and anticancer agent. It is a synthetic monophosphate with a modified 2'-hydroxyl group and a deoxyribose sugar backbone. It has been shown to inhibit HIV replication in vitro by interfering with the synthesis of viral DNA and RNA, which may be due to its ability to bind to the viral reverse transcriptase enzyme. 2'-TFA-NH-dG has also been shown to have anticancer activity against human A549 cells in vitro by inhibiting the proliferation of these cells. This drug is available for purchase as a white powder at CAS No. 144089-98-5.

    Formula:C12H13F3N6O5
    Purezza:Min. 95%
    Peso molecolare:378.26 g/mol

    Ref: 3D-NT57541

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  • 5'-O-DMT-2,2'-anhydrouridine

    CAS:

    5'-O-DMT-2,2'-anhydrouridine is a nucleoside that is an activator of RNA polymerase. This compound is novel and can be used for the synthesis of modified oligonucleotides and DNA. 5'-O-DMT-2,2'-anhydrouridine has anticancer properties and can be used in the treatment of cancer. 5'-O-DMT-2,2'-anhydrouridine has been shown to inhibit the growth of cancer cells by binding to DNA and inhibiting the production of RNA.

    Formula:C30H28N2O7
    Purezza:Min. 95%
    Peso molecolare:528.55 g/mol

    Ref: 3D-ND63210

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  • N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG


    N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine-3'-lcaa-CPG is a nucleotide analog with antiviral and anticancer activity. It is considered to be a novel nucleoside analogue. It is synthesized by attaching an acetyl group to the 2' position of the adenosine moiety, which prevents phosphorylation by kinase enzymes. This inhibits DNA synthesis and induces apoptosis in cancer cells.

    Purezza:Min. 95%
    Colore e forma:Powder

    Ref: 3D-ND57353

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  • 8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione

    CAS:

    8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione is a monophosphate nucleotide analog that inhibits viral DNA polymerases. It is a novel and high quality nucleoside phosphoramidite. 8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione is synthesized from 2'-deoxyribonucleosides and modified ribonucleosides. The CAS number for the compound is 35763855 2.

    Formula:C10H12N4O5
    Purezza:Min. 95%
    Peso molecolare:268.23 g/mol

    Ref: 3D-ND145594

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  • 5'-O-DMT-N2-phenylacetylguanosine

    CAS:

    5'-O-DMT-N2-phenylacetylguanosine is a novel synthetic nucleoside phosphoramidite which can be used for the synthesis of modified oligonucleotides. It has been shown to be an activator, anticancer, and antiviral agent in vitro. 5'-O-DMT-N2-phenylacetylguanosine is also a monophosphate, which can inhibit viral replication by interacting with the ribose sugar moiety of the nucleic acid strand. The antiviral activity has been demonstrated on human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 2 (HSV-2), and influenza A virus.

    Formula:C39H37N5O8
    Purezza:Min. 95%
    Peso molecolare:703.76 g/mol

    Ref: 3D-ND08925

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  • 8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution

    CAS:
    8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.
    Formula:C10H17N6O13P3·xNa
    Purezza:Min. 95%
    Peso molecolare:522.2 g/mol

    Ref: 3D-NA12011

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  • Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate

    CAS:

    Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate is a small molecule that is a potent inhibitor of diacylglycerol acyltransferase. The compound has been shown to be an efficient inhibitor of this enzyme, which is involved in the synthesis of diacylglycerol. Diacylglycerol acyltransferase catalyzes the transfer of an acyl group from an acyl-carrier protein (ACP) to glycerol 3-phosphate, forming lysophosphatidic acid and releasing CoA. The inhibition of this enzyme leads to drastically reduced levels of diacylglycerol, which may have implications for the treatment of metabolic syndrome and diabetes.

    Formula:C8H8F3N3O2
    Purezza:Min. 95%
    Peso molecolare:235.16 g/mol

    Ref: 3D-NE57446

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  • 3'-O-Methyl-5'-guanylic acid

    CAS:

    3'-O-Methyl-5'-guanylic acid is a novel antiviral, synthetic deoxyribonucleoside which is activated by phosphoramidites to produce 3'-O-methyl-5'-guanylic acid phosphoramidite. It has high purity and quality and can be used as a nucleoside activator for DNA synthesis. 3'-O-Methyl-5'-guanylic acid has been shown to be an anticancer agent that inhibits the growth of cancer cells in vitro by inhibiting DNA synthesis and cell division. This drug also has a potential use as an antiviral agent.

    Formula:C11H16N5O8P
    Purezza:Min. 95%
    Peso molecolare:377.25 g/mol

    Ref: 3D-NM165059

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  • 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine

    CAS:

    3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is a nucleoside phosphoramidite that is synthesized by the reaction of 3',5'-O-[Tetrakis(trimethylsiloxy)silyl]guanosine with tetrakis(1-methylethyl) siloxane. It is a novel monophosphate analogue of guanosine and has antiviral, anticancer and activator properties. 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is not toxic to cells and can be used in the treatment of cancer.

    Formula:C22H39N5O6Si2
    Purezza:Min. 95%
    Peso molecolare:525.75 g/mol

    Ref: 3D-NT16564

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  • 2'-O-Hexylaminoguanosine


    2'-O-Hexylaminoguanosine is a modified nucleoside that has antiviral properties. It is an activator of the human immune system and is used to treat cancer. 2'-O-Hexylaminoguanosine inhibits the synthesis of DNA by phosphoramidite addition to the monophosphate form of guanosine, which prevents RNA synthesis and therefore also protein synthesis. It also has anticancer effects by inhibiting the growth of cells in culture.

    Purezza:Min. 95%

    Ref: 3D-NH158886

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  • N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine


    N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to inhibit the replication of HIV in vitro and in vivo, and also inhibits the replication of hepatitis B virus. N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is active against cancer cells in vitro and inhibits the growth of human breast cancer xenografts in athymic mice. This compound also has high purity, high quality, and novel properties.

    Formula:C33H33N5O6
    Purezza:Min. 95%
    Peso molecolare:595.65 g/mol

    Ref: 3D-NA08597

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  • 3',5'-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-o-methyluridine

    CAS:

    3',5'-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine is a novel monophosphate nucleoside analog that is activated by T4 polynucleotide kinase. It is synthesized from the corresponding phosphoramidite and reacts with the 5'-OH group of a ribonucleoside to form a 3',5'-di-O-acetylribonucleoside. The diacetyl group confers increased stability to the molecule and also provides an acetyl group for incorporation into DNA. This compound has antiviral activity against herpes simplex virus type 1 (HSV1) in cell culture and has shown anticancer properties in animal studies.

    Formula:C23H27FN2O8
    Purezza:Min. 95%
    Peso molecolare:478.5 g/mol

    Ref: 3D-UJB35532

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  • Cytidine 5'-monophosphate sodium salt

    CAS:

    Cytidine 5'-monophosphate sodium salt is a nucleotide that is found in RNA and DNA. Cytidine 5'-monophosphate sodium salt is an intermediate in the biosynthesis of uridine, choline, and saccharose. It also plays an important role in the immune system as it can be a precursor for immunoglobulins. The reaction rate of cytidine 5'-monophosphate sodium salt with lipase has been shown to be constant at pH 7.5-8.0 and 37°C. This product has been shown to have emulsifying properties by forming micelles with water-immiscible solvents such as hexane or heptane, which may be due to its ability to form hydrogen bonds with other molecules such as saccharose or guanosine. Cytidine 5'-monophosphate sodium salt can also be used as a chromatographic material for separating saccharose from other sugars

    Formula:C9H14N3O8P·xNa
    Purezza:Min. 95 Area-%
    Colore e forma:White Off-White Powder
    Peso molecolare:323.2 g/mol

    Ref: 3D-NC00007

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  • 1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole

    CAS:
    1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole is a nucleoside that can be used as an activator for phosphoramidite synthesis. It is also known to have antiviral, anticancer, and antimalarial properties. 1-(2-Deoxy-b-D-ribofuranosyl)-4-methylindole has been shown to inhibit the proliferation of human leukemia cells in culture. It has also been shown to suppress HIV replication in vitro by inhibiting viral RNA synthesis.
    Formula:C14H17NO3
    Purezza:Min. 95%
    Peso molecolare:247.3 g/mol

    Ref: 3D-ND06396

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  • 5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid

    CAS:
    5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid is a pyrimidine derivative that inhibits protein kinases. The compound has been shown to inhibit the activity of protein kinase C, which is involved in mediating inflammatory responses, and phosphorylation of the insulin receptor substrate 1. 5-Bromo-2-methylsulfanyl-pyrimidine-4-carboxylic acid is an efficient inhibitor of kinases and can be used as a lead compound for the development of new compounds with therapeutic potential.
    Formula:C6H5BrN2O2S
    Purezza:Min. 95%
    Peso molecolare:249.09 g/mol

    Ref: 3D-NB44268

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  • N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine

    CAS:

    N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine is a novel nucleoside with anticancer and antiviral properties. It is an antiviral that inhibits the synthesis of viral DNA by blocking the incorporation of ribonucleotide triphosphates into DNA, while leaving intact the synthesis of deoxyribonucleotides and phosphoramidites. In addition, it is a potent inhibitor of cellular DNA polymerases that catalyze synthesis of DNA from deoxyribonucleoside triphosphates. N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine also has antitumor activity in animal models.

    Formula:C24H23N5O5
    Purezza:Min. 95%
    Peso molecolare:461.5 g/mol

    Ref: 3D-SFA97940

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  • 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:

    2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a novel antiviral nucleoside that has the potential to be used in the treatment of various viral infections. It is synthesized from 2',3'-dideoxyadenosine monophosphate and lithium salt, and has been shown to have high antiviral activity against DNA viruses such as herpes simplex virus and adenovirus. It also inhibits the replication of RNA viruses such as influenza A virus, vesicular stomatitis virus, and measles virus. 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a modified nucleoside that is phosphoramidite activated with a group at the 2' position on the ribose sugar. The phosphate group can be removed by hydrolysis or enzymatic catalysis, which leaves behind an unsaturated sugar moiety. This leads to an increased rate of incorporation into

    Formula:C10H12N5O11P3·4Li
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:498.91 g/mol

    Ref: 3D-ND32077

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  • 3'-Azido-3'-deoxythymidine-methyl-D3-b-D-glucuronide sodium salt

    Prodotto controllato

    3'-Azido-3'-deoxythymidine-methyl-D3-b-D-glucuronide sodium salt is a novel antiviral nucleoside phosphoramidite that has been shown to be an effective activator in the synthesis of diphosphate and triphosphate analogs. The novel antiviral nucleoside phosphoramidite was synthesized from 3'-azido-3'-deoxythymidine, methyl bromoacetate and sodium hydroxide in methanol at room temperature. It is structurally similar to the natural nucleosides, deoxyribonucleosides and ribonucleosides with modifications on the sugar moiety and phosphate group. This compound is a high quality synthetic material for use in pharmaceutical research, as an anticancer agent and as a potential antiviral drug.
    Formula:C16H17D3N5NaO10
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:468.36 g/mol

    Ref: 3D-NA04586

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  • 2-(3-Methylphenyl)pyrimidine-5-carbaldehyde

    CAS:
    2-(3-Methylphenyl)pyrimidine-5-carbaldehyde is a monophosphate nucleoside analog that can be used as an antiviral drug. It has shown cytotoxic activity against cells with a high DNA content, and it inhibits the synthesis of RNA and DNA. This compound could be useful for the treatment of HIV and other viral diseases.
    Formula:C12H10N2O
    Purezza:Min. 95%
    Peso molecolare:198.22 g/mol

    Ref: 3D-NM57435

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  • 5'-O-DMT-2'-O-(2-methoxyethyl)uridine

    CAS:

    5'-O-DMT-2'-O-(2-methoxyethyl)uridine is a modified nucleoside that is an antiviral and anticancer agent. It was first synthesized in the early 1980s, and has been shown to be active against a variety of viruses, such as herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). 5'-O-DMT-2'-O-(2-methoxyethyl)uridine inhibits the growth of cancer cells by interfering with DNA synthesis. This drug also has been shown to be an activator for DNA polymerases and is used as a building block for antiretroviral drugs.

    Formula:C33H36N2O9
    Purezza:Min. 95%
    Peso molecolare:604.65 g/mol

    Ref: 3D-ND76851

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  • rac-Lamivudine acid

    CAS:

    Lamivudine is an antiviral drug that is used as a nucleoside analogue. It is a prodrug that is converted to its active form, which inhibits the viral enzyme reverse transcriptase by interfering with the synthesis of viral DNA. Racemic lamivudine acid (LAM) crystallizes in the form of chains with hydrogen bonds oriented in an impurity plane. The LAM molecule has two substituents, one carboxylate and one oxathiolane group.

    Formula:C8H9N3O4S
    Purezza:Min. 95%
    Peso molecolare:243.24 g/mol

    Ref: 3D-NL27534

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  • Pyrimidine-4-carboxylic acid hydrazide

    CAS:
    Pyrimidine-4-carboxylic acid hydrazide (PCAH) is an antimycobacterial agent that inhibits the growth of Mycobacterium tuberculosis and other related species. PCAH is a ligand that binds to redox active metal ions, forming a supramolecular complex. The carboxyl group on PCAH reacts with the hydroxide ion in the presence of water to produce hydrogen peroxide, which in turn oxidizes the mycolic acids in the cell wall of M. tuberculosis, leading to cell death. The pyridine ring on PCAH is nucleophilic and can react with nucleophiles such as thiols or amines, which are found in proteins or peptides. This reaction results in nucleophilic substitutions, which inhibit bacterial protein synthesis and lead to cell death.
    Formula:C5H6N4O
    Purezza:Min. 95%
    Peso molecolare:138.13 g/mol

    Ref: 3D-NP57376

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  • 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine

    CAS:

    7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is a nucleoside analog that is used as an antiviral and anticancer drug. It has also been shown to have antimalarial activity. 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibits the replication of HIV by blocking the viral reverse transcriptase enzyme. This drug is a phosphoramidite monophosphate with a purity of 99%.

    Formula:C14H14ClN3
    Purezza:Min. 95%
    Peso molecolare:259.73 g/mol

    Ref: 3D-NB57451

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  • 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine

    CAS:

    3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine is a nucleoside that is used in the antiviral drug Aciclovir. It is an analog of 2'-deoxyadenosine and inhibits viral DNA synthesis by acting as a chain terminator. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine has shown some anticancer activity against human tumor cells in culture, but its mechanism of action is not well understood.

    Formula:C23H17Cl2FN2O7
    Purezza:Min. 95%
    Peso molecolare:523.29 g/mol

    Ref: 3D-ND22464

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  • Ammonium 4-nitrobenzoate dihydrate

    CAS:

    Ammonium 4-nitrobenzoate dihydrate is a corrosion inhibitor that prevents the corrosion of metal parts and other materials. It is used in the production of plastics, coatings, adhesives, and lubricants. The corrosion inhibition activity of aminobenzoates can be attributed to their ability to form hydrogen phosphate (HPO) anions as well as their ability to complex with metal ions. The hydration process is also important for the corrosion inhibition activity of ammonium 4-nitrobenzoate dihydrate. This process involves the release of water molecules from the ammonium salt, which provide a protective coating around the metal surface. Ammonium 4-nitrobenzoate dihydrate also has additive properties that are beneficial for other industrial applications such as antistatic agents, surfactants, and stabilizers.

    Purezza:Min. 95%

    Ref: 3D-NA30959

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  • DdCTP trilithium

    CAS:

    2',3'-Dideoxycytidine-5'-triphosphate trilithium salt (ddCTP) is a nucleoside analogue that has been shown to inhibit the enzyme activity of DNA polymerase. The ddCTP is a prodrug, which is activated by phosphorylation catalyzed by cellular kinases and then hydrolyzed to its active form, dideoxycytidine triphosphate (ddCTP). This drug also inhibits the synthesis of DNA and RNA. In vitro studies have shown that ddCTP causes cell lysis in murine sarcoma virus-infected cells, although it does not affect uninfected cells. 2',3'-Dideoxycytidine-5'-triphosphate trilithium salt has been shown to be an effective inhibitor of HIV reverse transcriptase and HIV protease in biochemical assays. It has also been found to be an effective inhibitor of mouse monoclon

    Formula:C9H13N3Li3O12P3
    Purezza:Min. 95%
    Colore e forma:Liquid
    Peso molecolare:468.96 g/mol

    Ref: 3D-ND10280

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  • 5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuanosyl)-1H-benzimidazole

    CAS:
    5,6-Dichloropurine-1-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-1H-benzimidazole is an antiviral agent that has shown activity against RNA viruses. It is a modified nucleoside monophosphate that inhibits the synthesis of viral ribonucleic acid (RNA) by binding to the enzyme RNA polymerase. 5,6-Dichloropurine is also a novel anticancer drug with antiangiogenic and antitumor properties. The compound was found to be effective in inhibiting the growth of human cancer cells in vitro. 5,6-Dichloropurine has been shown to inhibit protein synthesis through inhibition of diphosphate activation of ribonucleotide reductase and DNA polymerase. This product is synthesized using high purity and high quality reagents with excellent yield. It can be used as an
    Formula:C18H18Cl2N2O7
    Purezza:Min. 95%
    Peso molecolare:445.25 g/mol

    Ref: 3D-ND16534

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  • 2',3'-O-Isopropylidene-6-thioinosine

    CAS:

    2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.
    2',3'-O-Isopropylidene-6-thioinos

    Formula:C13H16N4O4S
    Purezza:Min. 95%
    Peso molecolare:324.36 g/mol

    Ref: 3D-NI08025

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  • 3′-Guanylic acid disodium

    CAS:

    3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.

    Formula:C10H14N5O8P•Na2
    Purezza:Min. 95%
    Peso molecolare:409.2 g/mol

    Ref: 3D-NG182606

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  • N2-Benzoylguanosine

    CAS:

    N2-Benzoylguanosine is a nucleotide derivative that is formed by the acetylation of guanosine. It has been shown to act as a buffer in alkaline solutions and isomerizes to its n-oxide form when heated. N2-Benzoylguanosine reacts with peroxides such as hydrogen peroxide, glyoxal, and organic peroxides, forming hydroperoxide intermediates that can be converted into other products. The acidic hydrolysis of N2-benzoylguanosine yields the corresponding 6-benzoyladenosines. It has been shown to enhance the activity of uridine in inhibiting bacterial growth, while also acting as an inhibitor of viral RNA synthesis. This compound also reacts with nitrous acid to form an n6-benzoyladenosine derivative that inhibits the formation of RNA chains during transcription.

    Formula:C17H17N5O6
    Purezza:Min. 95%
    Colore e forma:White to beige solid.
    Peso molecolare:387.35 g/mol

    Ref: 3D-NB06331

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  • 5-Methyl-L-uridine

    CAS:

    5-Methyl-L-uridine is an antiviral drug which belongs to a class of compounds called nucleoside analogues. It is used in the treatment of chronic hepatitis B and C, as well as for prevention of hepatitis A and B. 5-Methyl-L-uridine inhibits the virus by turning off the production of viral DNA and RNA, through interactions with the virus's polymerase chain reaction process. This drug also prevents protein synthesis in cells infected with viruses such as HIV, herpes simplex virus type 1, and influenza A virus. 5-Methyl-L-uridine is a prodrug that is converted to its active form, uridine monophosphate, by enzymes in the liver. The cytotoxic effects of 5-methyluridine on cancer cells have been shown to be due to inhibition of cellular DNA synthesis and repair pathways.

    Formula:C10H14N2O6
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:258.23 g/mol

    Ref: 3D-NM06240

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  • 2',3',5'-Tri-O-acetylinosine

    CAS:

    2′,3′,5′-Tri-O-acetylinosine is a protected form of the nucleoside inosine, with potential for use in the preparation of modified nucleotides and nucleoside analogs.

    Formula:C16H18N4O8
    Purezza:Min. 95%
    Colore e forma:White To Off-White Solid
    Peso molecolare:394.34 g/mol

    Ref: 3D-NT06708

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  • 5′-O-DMT-LNA N-Bz adenosine

    CAS:

    5′-O-DMT-LNA N-Bz adenosine is a novel nucleoside that has been modified with an aminooxy group. The compound is synthesized by the phosphoramidite method and it is designed for use in antiviral and anticancer research. 5′-O-DMT-LNA N-Bz adenosine can be used as a substrate for DNA polymerases and other enzymes to produce nucleic acid strands. This product is CAS No. 206055-74-5, monophosphate, Phosphoramidites, Synthetic, Deoxyribonucleosides, Anticancer, Ribonuclesides, High purity.

    Formula:C39H35N5O7
    Purezza:Min. 95%
    Peso molecolare:685.73 g/mol

    Ref: 3D-ND182842

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  • DMTr-TNA-C(Bz)-amidite

    CAS:

    Please enquire for more information about DMTr-TNA-C(Bz)-amidite including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C45H50N5O8P
    Peso molecolare:819.9 g/mol

    Ref: 3D-PD184482

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  • 2'-Deoxy-4'-ethynyl-2-fluoroadenosine

    CAS:

    2'-Deoxy-4'-ethynyl-2-fluoroadenosine (EFdA) is an analog of adenosine. EFdA is a potent inhibitor of HIV replication, and has been shown to be effective against other viruses such as influenza virus, herpes simplex virus, and vesicular stomatitis virus. EFdA was the first nucleoside analog to show antiviral activity in tissue culture against these viruses. This drug also inhibits the synthesis of mitochondrial rRNA and reduces the formation of mitochondrial DNA in human cells by inhibiting mitochondrial DNA polymerase γ. EFdA also prevents the binding of monoclonal antibodies to human B lymphocytes, which may be due to its steric interactions with plasma RNA. This drug is metabolized by cytochrome P450 2C8 and 2C9 into a variety of metabolites that are excreted in urine as glucuronides or sulfates. EFdA has a long

    Formula:C12H12FN5O3
    Purezza:Min. 95%
    Peso molecolare:293.25 g/mol

    Ref: 3D-ND45638

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  • Ribavirin 5'-triphosphate triethylammonium salt - 10 mM aqueous solution

    CAS:

    Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.

    Formula:C8H15N4O14P3•(C6H15N)x
    Purezza:Min. 95 Area-%
    Colore e forma:Clear Liquid
    Peso molecolare:789.73

    Ref: 3D-NR12804

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  • 5'-O-Tosylthymidine

    CAS:

    5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.

    Formula:C17H20N2O7S
    Purezza:Min. 95%
    Peso molecolare:396.42 g/mol

    Ref: 3D-NT10016

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  • 2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate

    CAS:

    10umol is approx 5mg.2'-O-(2-Methoxyethyl)guanosine 5'-monophosphate is a novel nucleoside phosphorylated on the 5' position

    Purezza:Min. 95%

    Ref: 3D-NM71847

    ne
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  • 2-Chloroadenosine 5'-monophosphate triethylamine salt

    CAS:

    2-Chloroadenosine 5'-monophosphate triethylamine salt is a phosphoramidite that has anticancer and antiviral activities. It is synthesized by reacting 2-chloroadenosine with triethylamine. This product has a novel chemical structure and it can be used as an activator for the synthesis of modified DNA, RNA, and other nucleosides. It is also used in the manufacture of deoxyribonucleosides, ribonucleosides, and other nucleotides.

    Formula:C10H13ClN5O7P·C12H30N2
    Purezza:Min. 95%
    Peso molecolare:584.05 g/mol

    Ref: 3D-NC10383

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  • 2',3'-Dideoxy-3',5-difluorocytidine

    CAS:

    2',3'-Dideoxy-3',5-difluorocytidine (ddF) is a nucleotide analogue that inhibits the viral polymerase. It binds to the enzyme and prevents it from synthesizing DNA, which is needed for viral replication. ddF has been shown to be effective against different types of cancer cells, including breast and prostate cancers. This drug also has antiviral properties and is used as an antiviral agent in AIDS therapy. ddF may also be used as a precursor in the synthesis of other nucleosides or nucleotides.

    Purezza:Min. 95%

    Ref: 3D-ND144806

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  • dNaM

    CAS:

    dNaM is a metabolite of DNA that has been shown to be a potential biomarker for metabolic disorders and autoimmune diseases. dNaM levels are elevated in the blood of pregnant women, which may serve as a marker for preeclampsia. Elevated levels have also been observed in patients with type 2 diabetes, obesity, and cancer. Methylation plays an important role in dNaM metabolism. The enzyme DNA methyltransferase (DNMT) catalyzes the transfer of methyl groups from S-adenosyl methionine to cytosine residues on the DNA molecule. DNMT activity is increased by high body mass index (BMI), low vitamin B12 levels, and HIV infection. This enzyme is also inhibited by valproic acid and deprenyl, which may affect dNaM methylation status.

    Formula:C16H18O4
    Purezza:Min. 95%
    Peso molecolare:274.31 g/mol

    Ref: 3D-SUB89319

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  • Archaeosine

    CAS:

    Archaeosine is a low energy chemical compound that inhibits the enzyme transcriptase polymerase chain reaction (PCR), which is an enzyme that catalyzes the synthesis of DNA from RNA. Archaeosine has significant interactions with human proteins, such as leukocyte antigen, and can be used to study protein-protein interactions and enzyme kinetics. The asymmetric synthesis of archaeosine has been studied in rat liver microsomes, which is a type of cell found in the tissues of the liver. Archaeosine also prevents bacterial enzymes from synthesizing DNA.

    Formula:C12H16N6O5
    Purezza:Min. 95%
    Peso molecolare:324.29 g/mol

    Ref: 3D-NA159487

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