Nucleosidi

Sold by weight of nucleoside as solution in ethanol.

3'-Amino-3'-deoxy-5'-O-trityl-D3-thymidine is a nucleoside and deoxyribonucleoside. It is an antiviral and anticancer agent that inhibits the synthesis of DNA by competitively inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 3'-Amino-3'-deoxy-5'-O-trityl-D3-thymidine has been shown to be effective in treating HIV, herpes zoster, and cancer cells.

<p>N2-Phenylacetyl-L-guanosine is a nucleoside that has been synthetically modified to have the desired properties of an anticancer agent. This compound inhibits DNA synthesis and is therefore cytotoxic to cells. It also inhibits RNA synthesis and is antiviral. N2-Phenylacetyl-L-guanosine has been found to be effective in preventing the growth of leukemia cells, breast cancer cells, prostate cancer cells, and ovarian cancer cells. N2-Phenylacetyl-L-guanosine is a nucleotide analogue that can be used as a building block for DNA or RNA synthesis. It can be used as a phosphate donor in phosphoramidite chemistry and can activate other nucleosides for use in chemical biology.</p>

<p>2',3'-Dideoxy-5-iodouridine is a synthetic nucleoside analog derived from uridine, one of the natural building blocks of RNA. This molecule has been chemically modified to disrupt the normal processes of DNA and RNA synthesis, making it a candidate for antiviral and anticancer research.</p>

9-(b-D-Arabinofuranosyl)adenine is a nucleoside that is used as an antiviral agent. It binds to viral RNA and inhibits viral replication. 9-(b-D-Arabinofuranosyl)adenine has been shown to have potent side-effect profiles, including myocardial infarct, neuronal death, and immunological reactions. These effects are due to its ability to inhibit the synthesis of guanine nucleotides in the heart and brain cells, which are essential for energy production and neurotransmitter release respectively. 9-(b-D-Arabinofuranosyl)adenine also binds to toll-like receptors (TLRs), which are proteins found on the surface of cells that recognize invading microbes or foreign substances. This binding leads to activation of immune response pathways.

2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It is synthesized from 5'-O-trityluridine and 2'-deoxyribonucleosides. This nucleoside has antiviral and anticancer properties, which are due to the fact that it inhibits viral replication by inhibiting DNA polymerase and prevents cell proliferation. 2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine 3'-CE phosphoramidite is a high purity, high quality product that can be used in DNA synthesis and cancer treatment.

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<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-MMT-cytidine 3'-CE phosphoramidite is a novel nucleoside analog that has been synthesized by the incorporation of a methyl group at the 5′ position. This modification results in an increased cytotoxicity and cellular uptake in cancer cells. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-MMT-cytidine 3'-CE phosphoramidite also inhibits the replication of HIV and herpes simplex virus type 1 (HSV1) and type 2 (HSV2), which are responsible for AIDS and genital herpes, respectively.<br>N4 - Benzoyl - 2 ' - O - tert - butyldimethylsilyl - 5 ' - O - MMT - cytidine 3' CE phosphoram</p>

Guanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt (GMPP) is an analog of guanosine triphosphate that is enzymatically inactivated by the enzyme kinesin. GMPP inhibits the polymerization of microtubules by binding to the kinesin molecule and preventing it from binding to tubulin. GMPP has been shown to inhibit sephadex g-100 chromatography and act as a competitive inhibitor for protein synthesis in vitro. GMPP has also been shown to have a fat cell differentiation effect which may be due to its ability to inhibit microtubule polymerization.

3-N-Boc-5'-O-DMT-3'-fluorothymidine is a monophosphate nucleoside with antiviral and anticancer activity. It is a novel synthetic analogue of fluoro thymidine (FT) that has been shown to be an activator of DNA polymerase α, RNA polymerase β and γ, and protein kinase C. This compound is also an inhibitor of the reverse transcriptase enzyme HIV-1. 3-N-Boc-5'-O-DMT-3'-fluorothymidine has been shown to inhibit cancer cell growth in vitro and in vivo. The synthesis of this compound can be achieved by phosphoramidite chemistry using a commercially available automated synthesizer.

2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is a novel nucleoside analog that has been synthesized to have the same chemistry as 2,3'-dideoxycytidine 5'-C phosphoramidite. It has antiviral and anticancer properties. This compound can be used in the synthesis of oligonucleotides for DNA sequencing and for gene therapy. 2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is not toxic to normal cells, but it inhibits replication of viruses such as HIV and herpes simplex virus.

3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is a nucleoside analog and activator that inhibits the replication of DNA. It is a novel antiviral drug that has antiproliferative properties and may be useful in the treatment of cancer. 3'-Azido-N6-benzoyl-5'-O-DMT-2',3'-dideoxyadenosine is synthesized by reacting an activated phosphoramidite with 2',3'-dideoxyadenosine monophosphate to produce 3',5' dideoxythymidine 5'-monophosphate, which is then converted to 3',5' dideoxyuridine 5'-monophosphate. The last step involves the conversion of 3',5' dideoxyuridine 5'-monophosphate to 3' azidouridine 5'-monoph

<p>N2-Isobutyryl-9-(b-D-arabinofuranosyl)guanine is a monophosphate analog of guanine. It is a novel antiviral agent that inhibits the DNA polymerase and RNA polymerase activities of human immunodeficiency virus (HIV). The drug has a high purity and is available in large quantities.</p>

<p>N6-Dimethyl-3’-b-C-methyladenosine is a novel nucleoside analog that has antiviral and anticancer properties. It is a phosphoramidite, which can be used as an activator for the synthesis of modified oligonucleotides. N6-Dimethyl-3’-b-C-methyladenosine has been shown to activate ribonucleosides and deoxyribonucleosides in vitro. This compound also has anticancer properties, which may be due to its ability to act as an activator in the synthesis of DNA.</p>

<p>2'-O-Methyl-5-propynyluridine is a nucleoside that is selective to bacterial DNA. It has been shown to inhibit the binding of RNA polymerase and DNA gyrase, as well as the synthesis of RNA and DNA. This nucleoside also inhibits the formation of triplexes in vitro with oligonucleotides complementary to sequences in the 16S ribosomal RNA gene. 2'-O-Methyl-5-propynyluridine has been used for the measurement of RNA polymerase activity in bacteria, and its affinity for triplexes can be measured by gel shift assay.</p>

<p>7-Deaza-2'-deoxy-7-iodoadenosine is an oligomer with a stabilized backbone that has been shown to inhibit the growth of bacteria in vitro. It binds to DNA and prevents RNA synthesis. 7-Deaza-2'-deoxy-7-iodoadenosine is a synthetic nucleotide analogue that is used as a probe for mapping RNA sequences and as an inhibitor of bacterial growth. This compound is also used in the synthesis of oligodeoxynucleotides because it has a high affinity for guanine residues, which can be incorporated into the oligonucleotide chain by chemical ligation. The octameric form of 7-deaza-2'-deoxyadenosine is most active against bacterial cells.</p>

Kinetin is a plant hormone that regulates cell proliferation and differentiation. Kinetin riboside is a derivative of kinetin in which the ribose moiety has been converted to ribosyl-ribitol. Kinetin riboside has shown the ability to inhibit cancer cells by inducing apoptosis, which may be related to its ability to inhibit cyclin D2 and mitochondrial membrane potential. In addition, kinetin riboside has been shown to protect against oxidative stress and decrease mitochondrial function in cells. This compound may have therapeutic potential for cancer treatment and other diseases caused by oxidative stress or mitochondrial dysfunction.

10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite is a cholesterol-conjugated phosphoramidite. The cholesteryl group is a lipophilic moiety which can be used to enhance cellular uptake of oligonucleotides.

1-(b-L-Arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is a novel antiviral agent that is synthesized from ribonucleosides. It is an activator of the monophosphate form of RNA polymerase and inhibits the synthesis of DNA in cells. This drug has also been shown to be effective against cancer cells and may be useful for treatment of leukemia.

5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.