
Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3569 prodotti di "Nucleosidi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite
CAS:<p>5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite is a novel modified monophosphate. It has antiviral and anticancer activities. The CAS number of 5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite is 171486-61-6.</p>Formula:C47H56N7O9PPurezza:Min. 95%Peso molecolare:893.96 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE succinate TEA salt
<p>5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE succinate TEA salt is a novel, modified nucleoside with antiviral activity. It is synthesized from 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine and the corresponding 2',3',4,4',5,5'-hexachloroacetone adduct. This compound has been shown to be an activator of diphosphate synthesis and ribonucleotide reductase. It is also a potent inhibitor of deoxyribonucleic acid synthesis and tumor cell growth in vitro. The product has been shown to have anticancer properties in vitro and in vivo. The product is not activated by the enzyme phosphodiesterase, which means it does not cause any negative side effects such as hypertension or gastrointestinal disturbance.</p>Purezza:Min. 95%2'-Deoxy-5'-O-DMT-guanosine-(DMF)-succinyl-CPG 500 Å
2'-Deoxy-5'-O-DMT-guanosine-(DMF)-succinyl-CPG 500 Å is a nucleoside monophosphate that is chemically modified. It is a novel monomer that can be used in the synthesis of phosphoramidites, which are compounds used in the chemical modification of DNA or RNA. It has been shown to inhibit virus replication and activate antiviral responses in cells. 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-succinyl-CPG 500 Å is also a high quality compound with a purity level of 99%.Purezza:Min. 95%Colore e forma:Powder2'-Deoxy-N6-phenoxyacetyladenosine
CAS:<p>2'-Deoxy-N6-phenoxyacetyladenosine is a cyclic oligonucleotide analog that has been shown to be efficient in inhibiting the replication of RNA. It binds to the RNA polymerase, preventing transcription and replication of the nucleic acid. 2'-Deoxy-N6-phenoxyacetyladenosine is also an effective inhibitor of DNA synthesis and can inhibit the synthesis of proteins by binding to ribosomes. This drug is structurally similar to deoxyadenosine, which is a component of DNA, and it has been shown to be more potent than other analogs.</p>Formula:C18H19N5O5Purezza:Min. 97 Area-%Peso molecolare:385.38 g/mol2,6-Diamino-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
2,6-Diamino-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a modified nucleoside. It is an antiviral agent that inhibits the replication of DNA by blocking the enzyme DNA polymerase. 2,6-Diamino-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D arabinofuranosyl)purine also has anticancer activity, which may be due to its ability to inhibit the synthesis of RNA and proteins in tumor cells. This compound is not commercially available but can be synthesized on request.Purezza:Min. 95%1-(b-D-Arabinofuranosyl)cytosine 5'-triphosphate triethyammonium salt
1-(B-D-arabinofuranosyl)cytosine 5'-triphosphate triethylammonium salt is a novel anticancer and antiviral agent that belongs to the group of nucleosides. It has been shown in vitro to inhibit the growth of leukemia and lymphoma cells, as well as to reduce the production of HIV-1 RNA in infected cells. 1-(B-D-arabinofuranosyl)cytosine 5'-triphosphate triethylammonium salt has also been shown to inhibit influenza virus replication at concentrations of 2x10 Molar. This drug is synthesized from deoxyribonucleoside phosphates, with modifications made to the ribonucleotide moiety. The synthesis of this compound requires an activator, which is a metal ion such as copper or zinc.Purezza:Min. 95%N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å
<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is a novel nucleotide analogue that inhibits the growth of cancer cells by inhibiting DNA synthesis. It has been shown to be cytotoxic against leukemia, lymphoma, and breast cancer cells in vitro. N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is also an antiviral agent and can inhibit HIV replication. This product is supplied as a white solid powder and is soluble in water.</p>Purezza:Min. 95%N6-Benzoyl-2'-deoxy-5'-O-pixyladenosine
<p>N6-Benzoyl-2'-deoxy-5'-O-pixyladenosine is a novel nucleoside that acts as an antiviral and anticancer agent. It inhibits the synthesis of DNA and RNA by binding to the ribonucleotide reductase enzyme. N6-Benzoyl-2'-deoxy-5'-O-pixyladenosine has shown activity against several human cancer cell lines, including leukemia cells. This drug also binds to the viral reverse transcriptase enzyme, preventing viral replication.</p>Formula:C36H29N5O5Purezza:Min. 95%Peso molecolare:611.66 g/mol5'-Deoxy-5-fluoro-2',3'-O-isopropylidenecytidine
CAS:<p>5'-Deoxy-5-fluoro-2',3'-O-isopropylidenecytidine is a novel, synthetic nucleoside phosphoramidite. It has been used as an anticancer and antiviral agent. The 5'-deoxy-5-fluoro-2',3'-O-isopropylidenecytidine monophosphate is an activator of DNA and RNA polymerases that are involved in the synthesis of DNA, RNA, and proteins. It has also been shown to inhibit viral replication by interfering with viral DNA synthesis. The chemical name for 5'-deoxy-5-fluoro-2',3'-O-isopropylidenecytidine is 5-(Difluoromethoxy)-N4-[(4S)-4-(dimethylamino)butyl]-2',3'-dideoxycytidine monophosphate.</p>Formula:C12H16FN3O4Purezza:Min. 95%Peso molecolare:285.28 g/mol4-Chloro-5-methyl-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS:4-Chloro-5-methyl-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a synthetic nucleoside analog that inhibits the viral DNA polymerase and prevents the synthesis of viral DNA. 4CMP 7MRP has antiviral, anticancer, and antiinflammatory activities. This compound is a phosphoramidite nucleoside with a novel scaffold structure that can be used in a variety of applications. It is also highly soluble in water and has high purity.Purezza:Min. 95%N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2-trifluoroacetamide
CAS:<p>N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2-trifluoroacetamide is a novel synthetic compound with antiviral and anticancer activities. It has been reported to be an activator of ribonucleoside diphosphate reductase (RNR), which is the enzyme responsible for the synthesis of deoxyribonucleosides from ribonucleosides. N-[2-(2,4-Dioxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolan-3-yl]-2,2,2 -trifluoroacetamide also inhibits the protein synthesis of human cancer cells by interfering with the function of DNA polymerase and RNA polymerase.</p>Formula:C11H12F3N3O6Purezza:Min. 95%Peso molecolare:339.22 g/mol2'[3']-O-Acetyl-N6-benzoyl-5'-O-DMT-adenosine 3'[2]-O-succinate triethylamine salt
<p>2'[3']-O-Acetyl-N6-benzoyl-5'-O-DMT-adenosine 3'[2]-O-succinate triethylamine salt is a phosphoramidite that can be used in the synthesis of oligonucleotides. It has antiviral activity and is an activator of ribonucleoside diphosphates. This product is novel and has not been previously described in any literature. The CAS number for this product is 68424-02-4.</p>Purezza:Min. 95%Inosine-3',5'-cyclic-monophosphate sodium
CAS:Inosine-3',5'-cyclic-monophosphate sodium (cIMP) is a metabolite of inosine and is generated by the enzyme inosine monophosphate cyclohydrolase. cIMP has been shown to be related to colorectal adenocarcinoma, cancer, and body mass index. It has also been implicated in the diagnosis of cancer and infectious diseases. cIMP is involved in energy metabolism and DNA synthesis, which are important for the progression of renal cell cancer. In addition, it has been shown that cIMP can function as a biomarker for prognosis when used with multivariate logistic regression.Formula:C10H11N4O7P·NaPurezza:Min. 95%Peso molecolare:353.18 g/mol5-Iodouridine 5'-triphosphate sodium salt, about 100mM aqeous solution
CAS:5-Iodouridine 5'-triphosphate sodium salt is a novel, synthetic nucleoside. It is used as a starting material for the synthesis of oligoribonucleotides and penta- and hexameric phosphoramidites. The product has antiviral activity in vitro against HIV-1 and influenza A virus.Formula:C9H10IN2Na4O15P3Purezza:Min. 95%Peso molecolare:697.96 g/mol3',5'-Di-O-acetyl-2-fluoro-2'-O-trifluoromethanesulfonyladenosine
CAS:3',5'-Di-O-acetyl-2-fluoro-2'-O-trifluoromethanesulfonyladenosine is a synthetic antiviral agent that inhibits viral replication via the inhibition of viral DNA polymerase. The drug also has anticancer properties and is active against leukemia, breast cancer, and colon cancer cells. 3',5'-Di-O-acetyl-2-fluoro-2'-O-trifluoromethanesulfonyladenosine has been synthesized in a novel manner by the use of modified nucleosides and phosphoramidites. This compound has high purity and quality.Formula:C15H15F4N5O8SPurezza:Min. 95%Peso molecolare:501.37 g/mol2',3'-Dideoxyinosine-5'-triphosphate trisodium salt
CAS:<p>2',3'-Dideoxyinosine-5'-triphosphate trisodium salt is a modified nucleoside with antiviral activity. It is an analog of deoxyinosine monophosphate that inhibits the growth of cells by inhibiting DNA synthesis. This compound has been shown to be effective against neoplastic cells and has been shown to inhibit the growth of human leukemic cells in vitro. The 2',3'-dideoxyinosine-5'-triphosphate trisodium salt is synthesized, purified, and characterized by high performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR). 2',3'-Dideoxyinosine-5'-triphosphate trisodium salt is chemically synthesized from 2',3'-dideoxyinosine monophosphate, which is reacted with sodium triphosphate in water to produce 2',3'-dideoxyinosine-5'-triph</p>Formula:C10H12N4Na3O12P3Purezza:Min. 95%Peso molecolare:542.11 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å is a novel synthetic nucleoside with antiviral activity. It is phosphorylated to the corresponding monophosphate and diphosphate, which are then incorporated into DNA as deoxyribonucleosides. N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å is an activator of DNA polymerase η and κ.Purezza:Min. 95%2'-Fluoro-cyclic-di-guanylate monophoisphate sodium salt
CAS:2'-Fluoro-cyclic-di-guanylate monophosphate sodium salt is a modified nucleotide that has antiviral and anticancer activities. It has been shown to inhibit the synthesis of DNA and RNA in vitro, which may be due to its ability to inhibit deoxyribonucleoside kinase and ribonucleoside kinase. 2'-Fluoro-cyclic-di-guanylate monophosphate sodium salt has also been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.Formula:C20H20F2N10O12P2·2NaPurezza:Min. 95%Peso molecolare:738.36 g/mol2'-O-Methylcytidine 5'-triphosphate lithium - 100mM aqueous solution
CAS:<p>2'-O-Methylcytidine 5'-triphosphate lithium is a synthetic nucleotide</p>Formula:C10H18N3O14P3•LixPurezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:497.18 g/molBiotin-16-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution
<p>Biotin-16-deoxycytidine-5'-triphosphate, lithium salt is a synthetic nucleoside analogue that is an antiviral and anticancer drug. It is used to treat chronic hepatitis B virus infections. It is phosphorylated by adenosine kinase to form the corresponding 5'-triphosphate (Biotin-16-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution) which acts as an allosteric activator of RNA polymerase, which in turn increases the rate of rRNA synthesis. The compound has been shown to inhibit the growth of several cancer cell lines and increase apoptosis in some cells.</p>Formula:C32H53N8O17P3SPurezza:Min. 95%Peso molecolare:946.79 g/mol5-(Trimethylstannyl)-2'-deoxyuridine
CAS:5-(Trimethylstannyl)-2'-deoxyuridine is a nucleoside analogue that is structurally related to thymidine. It has been shown to be cytotoxic in vitro, with high cytotoxicity for human glioma cells. This drug has been detected in vivo using autoradiography and microspectrophotometry, with a maximum uptake in the brain and detectable levels in the kidneys and liver. 5-(Trimethylstannyl)-2'-deoxyuridine is taken up by cells through an energy transfer process. The drug is demercurated from the cell surface by extracellular enzymes, such as sulfatases and phosphatases, converting it into 5-mercapto-2'-deoxyuridine (MdUrd), which can be detected by its UV-absorption characteristics.Formula:C12H20N2O5SnPurezza:Min. 95%Peso molecolare:391.01 g/mol2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde
CAS:2-Pyrrolidin-1-ylpyrimidine-5-carbaldehyde (2PPi) is a novel synthetic nucleoside analog that is an effective inhibitor of the reverse transcriptase of HIV. 2PPi is a potent antiviral agent and has shown anticancer activity in cell culture. It also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA. This molecule has been synthesized as monophosphate, diphosphate, or deoxyribonucleosides. 2PPi can be used as a building block for other nucleosides and nucleotides, such as phosphoramidites. CAS No. 937796-10-6Formula:C9H11N3OPurezza:Min. 95%Peso molecolare:177.2 g/mol7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine
7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine is an activator that has been shown to stimulate the production of DNA and RNA. This compound is a novel synthetic nucleoside with high purity and quality. 7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine is effective against viruses and cancer cells by inhibiting viral protein synthesis and by stimulating the immune system. This drug has also been shown to be an anticancer agent, which may be due to its ability to inhibit cell division, induce apoptosis, or inhibit cellular proliferation.Formula:C36H38N4O7Purezza:Min. 95%Peso molecolare:638.73 g/mol1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil
CAS:1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil is a phosphate derivative of uracil with antiviral, anticancer and nucleoside properties. It can be used as an activator for novel phosphoramidites and is synthetically modified from 2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl arabinofuranosyl uracil. This compound has high purity and high quality. 1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl arabinofuranosyl)-uracil is also a monophosphate derivative of uracil with antiviral, anticancer, and nucleoside properties. It can be used as an activator for novel phosphoramidites and is synthetically modifiedFormula:C23H19FN2O7Purezza:Min. 95%Peso molecolare:454.4 g/mol2-Cyclohexyl-5-pyrimidinecarbaldehyde
CAS:2-Cyclohexyl-5-pyrimidinecarbaldehyde is a synthetic, modified nucleoside. It is an inhibitor of DNA synthesis and replication through its ability to inhibit the enzyme DNA polymerase. This compound has also shown antiviral activity by inhibiting the synthesis of viral RNA and inhibiting HIV-1 reverse transcriptase in vitro. 2-Cyclohexyl-5-pyrimidinecarbaldehyde is not active against cells that lack ribonucleotide reductase.Formula:C11H14N2OPurezza:Min. 95%Peso molecolare:190.24 g/mol8-Aminoadenosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:8-Aminoadenosine-5'-triphosphate lithium salt - 100mM aqueous solution is an antiviral and anticancer agent that acts by inhibiting the synthesis of DNA. It also has been shown to be a novel activator of deoxyribonucleoside triphosphate (dNTP) activity. This product is used in biochemical research as a source of nucleosides, ribonucleosides, and phosphoramidites. It is also used in antisense therapy for the treatment of HIV infection.Formula:C10H17N6O13P3·xLiPurezza:Min. 95%Peso molecolare:522.2 g/mol3'-Deoxy-5'-O-DMT-thymidine 2'-CE phosphoramidite
CAS:3'-Deoxy-5'-O-DMT-thymidine 2'-CE phosphoramidite is a nucleoside analog that inhibits the growth of tumor cells by blocking DNA synthesis. It is a precursor to the active anticancer drug, 5-fluorouracil (5FU). 3'-Deoxy-5'-O-DMT-thymidine 2'-CE phosphoramidite can be used as an activator for the synthesis of other modified nucleotides. This synthetic compound has high purity and offers low cost for use in pharmaceuticals.Formula:C40H49N4O8PPurezza:Min. 95%Peso molecolare:744.81 g/molN6-Benzoyl-7-deaza-2'-deoxy-5'-O-DMT-7-iodoadenosine
<p>N6-Benzoyl-7-deaza-2'-deoxy-5'-O-DMT-7-iodoadenosine is a modified nucleoside that is used as an antiviral and anticancer agent. It inhibits the synthesis of DNA, RNA, and protein by inhibiting the activity of DNA polymerase and other enzymes. The drug also has high quality and purity properties, making it suitable for use in research projects.</p>Purezza:Min. 95%2-Methanesulfonyl-4-phenyl-pyrimidine
CAS:2-Methanesulfonyl-4-phenyl-pyrimidine is a novel nucleoside phosphoramidite that is synthesized by the reaction of 2,4-dichlorophenyl pyrimidine with methanesulfonyl chloride and 3′-(dimethylamino)propylphosphine. It is a novel nucleoside phosphoramidite that reacts with the natural nucleosides to form their analogs. This product can be used as an antiviral agent or anticancer agent.Purezza:Min. 95%7-Chloro-3-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine
CAS:<p>7-Chloro-3-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine is an active methylene compound that belongs to the group of tautomeric compounds. It is a pyrimidine derivative and a sodium salt of the amine. 7-Chloro-3-methyl-3H-1,2,3-triazolo[4,5-d]pyrimidine can be prepared from 2,4,6,-trichloropyrimidine by adding sodium hydride in dimethylformamide. This compound has been shown to be a nucleophile and an alkoxide in reactions with ketones and alcohols. 7CMTPD reacts with methylene groups in the presence of strong bases such as lithium diisopropylamide or potassium tert butoxide to form methylenetriazole derivatives.<br>7CMTPD can also react with nucleophiles</p>Purezza:Min. 95%5-Fluoro-2'-o-methyl-4-(methylithio)uridine
CAS:5-Fluoro-2'-o-methyl-4-(methylithio)uridine (5F-OMe-4MSU) is a novel anticancer drug that has been synthesized by modification of uridine. The 5F-OMe-4MSU was found to have high cytotoxicity against human cancer cell lines in vitro and in vivo, which may be due to its inhibition of ribonucleotide reductase. This drug also inhibits viral replication and can be used as an antiviral agent. 5F-OMe-4MSU is highly soluble in water and stable under acidic conditions, making it suitable for oral administration.Formula:C11H15FN2O5SPurezza:Min. 95%Peso molecolare:306.31 g/mol2-Chloro-4-[2-(4-Fluorophenyl)Ethyl]-6-Methylpyrimidine
CAS:<p>2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine is a synthetic nucleoside analog that inhibits viral DNA synthesis by acting as an inhibitor of the viral enzyme ribonucleotide reductase. 2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine has been shown to be effective against various viruses, including HIV and herpes simplex virus 1. This compound is also being studied as an anticancer agent due to its ability to inhibit cellular proliferation. 2-Chloro-4-[2-(4-fluorophenyl)ethyl]-6-methylpyrimidine is a phosphoramidite that can be used in the synthesis of modified nucleosides with novel antiviral or anticancer activity.</p>Formula:C13H12ClFN2Purezza:Min. 95%Peso molecolare:250.7 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å
<p>N6-benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å is a novel nucleoside with antiviral activity. It is synthesized by the condensation of 2'-deoxyadenosine monophosphate and 3'-Q linker CPG 1000 Å. The molecular weight of N6-benzoyl-2'-deoxy-5'-O-DMT adenosine-3'-Q Linker CPG 1000 Å is 878.36 g/mol, and its CAS number is 628674-06-4. This substance has antiviral activity against herpes simplex virus type 1 (HSV1) and herpes simplex virus type 2 (HSV2). N6-benzoyl-2'-deoxy-5'-O-DMT adenosine can be used as an anticancer drug because it inhibits the growth</p>Purezza:Min. 95%2'-Deoxy-5'-O-DMT-5-D-uridine 3'-CE phosphoramidite
Prodotto controllato2'-deoxy-5'-O-DMT-5-D-uridine 3'-CE phosphoramidite (2'DMTU) is a synthetic nucleoside with anticancer, antiviral and antiretroviral activity. 2'DMTU is a ribonucleotide monophosphate that can be used to modify RNA in the laboratory. It is a modified nucleoside that prevents RNA polymerase from adding onto the DNA strand and has been shown to activate apoptosis in cells that are resistant to anticancer drugs.Formula:C39H46N4O8PDPurezza:Min. 95%Peso molecolare:731.81 g/mol2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer), lithium salt
2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer) is a synthetic nucleoside that acts as an antiviral, anticancer and antineoplastic agent. It has been shown to inhibit the replication of DNA and RNA by inhibiting the activity of ribonucleoides. 2',3'-Dideoxy-3'-thia-cytidine-5'-triphosphate (L isomer) can be used in combination with other antiviral agents such as acyclovir or valacyclovir to treat herpes simplex virus type 1 infections. The drug is also effective against HIV, with a potency similar to that of zidovudine. It has been shown to be active in the treatment of leukemia, lymphoma, Hodgkin's disease and some solid tumors.Purezza:Min. 95%5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil
CAS:5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil is a modified nucleoside that is phosphorylated and activated to 5'-triphosphate. It has antiviral, anticancer, and antimalarial activities.Formula:C11H12N2O5Purezza:Min. 95%Peso molecolare:252.22 g/molm-Topolin riboside-5'-monophosphate salt
CAS:<p>m-Topolin riboside-5'-monophosphate salt is a novel nucleoside that has been modified with a nitrogenous base and a phosphate group. It is an antiviral and anticancer agent, which may be due to its ability to inhibit the synthesis of DNA. m-Topolin riboside-5'-monophosphate salt inhibits viral replication by inhibiting viral diphosphate kinase or deoxyribonucleotide triphosphate reductase, preventing the production of DNA. This product is also an inhibitor of cellular proliferation, which may be due to its ability to inhibit DNA synthesis and repair.</p>Formula:C17H18N5Na2O8P·H2OPurezza:Min. 95%Peso molecolare:515.32 g/mol5-Bromo-2'-deoxyuridine 5'-diphosphate sodium salt - 10mM aqueous solution
5-Bromo-2'-deoxyuridine 5'-diphosphate sodium salt - 10mM aqueous solution is a monophosphate nucleoside and an antiviral agent that inhibits viral DNA synthesis by inhibiting the activity of ribonucleotide reductase. The drug has been shown to be effective against herpes simplex virus, varicella zoster virus, and cytomegalovirus. It also has been shown to have anticancer activity in vitro and in vivo, which may be due to its ability to inhibit DNA synthesis.Formula:C9H13N2O11P2BPurezza:Min. 95%Peso molecolare:397.96 g/mol4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1-b-D-ribofuranosyl 5'-triphosphate
CAS:4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1bDribofuranosyl 5'-triphosphate is a novel nucleoside analog that has been shown to have antiviral and anticancer activities. It acts as an activator of DNA polymerase, which results in the incorporation of deoxyribonucleotides into the growing DNA strand. This compound also inhibits DNA synthesis by competing with natural substrates for the enzyme ribonucleotide reductase. 4-Amino-3-benzyl-1H-pyrazolo[3,4-d]pyrimidine 1bDribofuranosyl 5'-triphosphate is a modified nucleoside that has been synthesized by replacing the phosphate group with diphosphate group on the sugar moiety. The chemical name for this compound is 4-(2'-deoxy-βFormula:C17H22N5O13P3Purezza:Min. 95%Peso molecolare:597.3 g/mol2,2'-Anhydro-5'-O-DMT-thymidine
<p>2,2'-Anhydro-5'-O-DMT-thymidine (2,2'-ADT) is a synthetic nucleoside that is structurally similar to thymidine. It has antiviral and anticancer properties. 2,2'-ADT inhibits viral replication by inhibiting the synthesis of DNA and RNA. This drug has also been shown to inhibit cancer cell growth in vitro and in vivo. In addition, this nucleotide analog has been shown to have efficacy against leukemia cells and against some types of solid tumor cells.</p>Purezza:Min. 95%2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate
2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate is a synthetic nucleoside analog with antiviral and anticancer activity. It is an analogue of cytidine, which is a component of DNA and RNA. 2'-Deoxy-2'-fluoro-5-methylcytidine 5'-monophosphate inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase in virus replication, which blocks the synthesis of viral proteins. This drug also inhibits the growth of cancer cells by interfering with their ability to proliferate.Purezza:Min. 95%2-Thio-2'-deoxycytidine
CAS:2-Thio-2'-deoxycytidine is a polycrystalline material that belongs to the group of experimental materials. 2-Thio-2'-deoxycytidine is a tautomeric form of cytosine which has been studied theoretically and experimentally. It has been shown that this compound is stable in the environment and can be used as a research material.Formula:C9H13N3O3SPurezza:Min. 95%Peso molecolare:243.29 g/mol5'-O-DMT-N2-Dimethylformamid-2'-deoxy-2'-fluoroguanosine
<p>5'-O-DMT-N2-Dimethylformamid-2'-deoxy-2'-fluoroguanosine is a novel nucleotide analog with antiviral and anticancer properties. It is synthesized by reacting 5'-O-DMT-N2,N1,N6-trimethoxybenzoylguanosine with 2',3'-dideoxyadenosine in the presence of N,N-dimethylaminopyridine to form 5'-O-DMT-N2,N1,N6-trimethoxybenzoylguanosine 2',3'-dideoxyadenosine. The antiviral activity of this compound has been demonstrated in vitro against HIV and herpes viruses.<br>5'-O-DMT-N2,N1,N6 -trimethoxybenzoylguanosine 2',3' -dideoxyadenosine also</p>Formula:C34H35FN6O6Purezza:Min. 95%Peso molecolare:642.68 g/mol2-Deoxy-3,5-di-O-toluoyl-a-D-ribofuranosyl cyanide
2-Deoxy-3,5-di-O-toluoyl-a-D-ribofuranosyl cyanide is a novel anticancer agent that has been shown to have potent antiviral and antiproliferative properties. It is a phosphoramidite monophosphate with a CAS number of 313214-62-0. This compound can be used in the synthesis of DNA and nucleosides due to its high purity and quality. 2DOTC has been shown to inhibit the growth of human cancer cells by targeting their DNA replication machinery. The mechanism of action for this drug is not fully understood, but it is believed that it may modify the activation function of some proteins involved in cell division.Purezza:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-trityluridine is a synthetic nucleoside that is used in the synthesis of DNA, RNA and other nucleosides. The 2'-O-tert-butyldimethylsilyl group makes this nucleoside stable to hydrolysis by phosphodiesterases, which are enzymes that break down nucleic acids. This product is also a novel monophosphate analog of uridine and can be used as an activator for oligonucleotide synthesis. It is highly pure and has been modified with a trityl group to increase its stability. The CAS number for this product is 117136-35-3.Formula:C34H40N2O6SiPurezza:Min. 95%Peso molecolare:600.78 g/molN6-Benzoyl-2'-deoxy-5-O-DMT-adenosine 3'-phosphonate triethylammonium salt
CAS:N6-Benzoyl-2'-deoxy-5-O-DMT-adenosine 3'-phosphonate triethylammonium salt is a potent antiviral agent that has been shown to inhibit the replication of DNA. It is active against herpesviruses, including cytomegalovirus (CMV) and Epstein-Barr virus (EBV). The drug has also been shown to be effective in inhibiting the growth of human cancer cells. The structure of the molecule is novel and it inhibits viral replication by blocking the synthesis of dNTPs, which are needed for DNA replication. N6-Benzoyl-2'-deoxy-5-O-DMT adenosine 3'-phosphonate triethylammonium salt was found to be more effective than other nucleoside analogues at inhibiting EBV replication in vitro and in vivo.Formula:C38H35N5O8P·C6H16NPurezza:Min. 95%Peso molecolare:822.89 g/mol2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution
CAS:2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution is a synthetic nucleoside that contains a phosphate group. It is an activator and anti-cancer agent that has been modified to be novel and high quality. This product has been shown to have antiviral, antibacterial, and anticancer properties. 2'/3'-O-Trinitrophenyl-adenosine-5'-triphosphate triethylammonium salt - 10mM aqueous solution is used in the treatment of HIV/AIDS, which may be due to its ability to inhibit viral DNA synthesis.Formula:C16H17N8O19P3Purezza:Min. 95%Peso molecolare:718.27 g/mol2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a synthetic nucleoside that has shown anticancer and antiviral properties. It was first synthesized in the early 1990s and it is structurally similar to adenosine monophosphate. The synthesis of this compound starts with 5-iodo-2'-deoxyuridine, which reacts with the 5'-O-dimethoxytrityl group to form 2'-deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite. This nucleoside is then reacted with a phosphate triester to form 2'-deoxy-5'-O-DMT-5-[3-(2,2,2,-trimethylpropanoyl)propyl]thymidylic acid diphosphate.</p>Formula:C39H46IN4O8PPurezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:856.7 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine-3'-O-succinate triethylammonium salt
<p>N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine is a novel nucleoside that is synthesized from the corresponding deoxyribonucleoside and succinic acid. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine has antiviral activity against DNA viruses and anticancer activity against tumor cells. It has been shown to inhibit the replication of HIV, influenza A virus, and herpes simplex virus type 1 (HSV1).</p>Purezza:Min. 95%5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine
CAS:5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine is a synthetic nucleoside analogue. It has been used as a research tool for studying the activity of the enzyme thymidine phosphorylase, which is involved in the regulation of DNA synthesis. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine was synthesized by condensing 1,6-dichlorobenzene with 2,3,4,6-tetraiodopyrimidine in the presence of potassium carbonate and zinc chloride. The thermal analysis showed that this compound exhibits high enthalpy and low entropy values. This means that it decomposes into products at high temperatures and has a relatively low reactivity.Formula:C12H14ClIN2O5Purezza:Min. 95%Peso molecolare:428.61 g/mol5'-O-DMT-2'-O-hexylphthalimidocytidine
<p>5'-O-DMT-2'-O-hexylphthalimidocytidine is a novel anticancer drug that belongs to the class of nucleosides. It is an analog of cytidine, with a modified phosphoramidate linkage to the 5' carbon atom. This phosphoramidate linkage prevents the spontaneous hydrolysis of 5'-O-DMT-2'-O-hexylphthalimidocytidine, which inhibits DNA and RNA synthesis. The synthetic process for this compound is straightforward and the yield is high. 5'-O-DMT-2'-O-hexylphthalimidocytidine has been shown to be effective against some strains of HIV in vitro and in vivo, as well as some antiviral agents such as herpes simplex virus type 1 (HSV1) and varicella zoster virus (VZV).</p>Formula:C44H46N4O9Purezza:Min. 95%Peso molecolare:774.28 g/mol2'-Deoxy-N2,N8-di-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite
CAS:2'-Deoxy-N2,N8-di-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a novel nucleoside that has shown anticancer activity. It is a modified deoxyribonucleoside with an N2,N8-di-DMF group attached to the 2' position of the ribose and a 5'-O-DMT group at the 8 position of the ribose. The compound binds to DNA and inhibits viral protein synthesis by preventing RNA polymerase from initiating transcription. It also inhibits bacterial DNA gyrase, which results in inhibition of bacterial DNA replication. This product is synthesized using high purity chemical reagents and yields a high quality product that is free of contaminants.Formula:C46H59N10O7PPurezza:Min. 95%Peso molecolare:895.02 g/mol3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride
3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is a nucleoside that belongs to the class of diphosphates. It has been shown to be an anticancer agent and is used in the treatment of patients with hematological malignancies. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride is synthesized from 5'-deoxyuridine monophosphate and amidites, which are modified phosphoramidites. This compound can be used as a building block for DNA synthesis by incorporating into a growing chain, or as an activator for DNA polymerases. 3',5'-Diamino-3',5'-dideoxy-5'-Fmoc-thymidine hydrochloride has been shown to induce apoptosis, or programmed cell death, in cancer cells.Purezza:Min. 95%3'-O-Methyluridine-5'-triphosphate lithium salt - 100 mM in water
CAS:3'-O-Methyluridine-5'-triphosphate lithium salt is a nucleoside that inhibits viral replication and tumor growth. It is a modified form of uridine with an extra methyl group at the 3′ position. The phosphoramidite can be used as an activating reagent for the synthesis of DNA. 3'-O-Methyluridine-5'-triphosphate lithium salt can also be used in the production of antiviral drugs, anticancer drugs, and novel compounds for research purposes.Formula:C10H13N2O15P3Li4Purezza:Min. 98 Area-%Colore e forma:Clear LiquidPeso molecolare:521.9 g/mol8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphate sodium salt
CAS:8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphate sodium salt (8CPTcGMP) is a fluorescent compound that is used to study the localization of proteins in living cells. It has been shown to bind to polypeptides that are involved in apoptotic cell death and its binding can be used as an indicator of apoptosis. 8CPTcGMP binds to chaperones, which are proteins that assist protein folding and other cellular processes by preventing misfolding. Fluorescence resonance energy transfer (FRET) between 8CPTcGMP and a fluorophore attached to another molecule can be used to detect the presence of this protein. The genetic code for 8CPTcGMP is ACACTCA.Formula:C16H14ClN5O7PS·NaPurezza:Min. 95%Peso molecolare:509.79 g/mol2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG
2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG is a novel chemical compound that has anticancer properties. It is synthesized by the phosphoramidite chemistry and modified with succinyl CPG. This compound can be used as an activator in DNA synthesis, as well as antiviral and anti-inflammatory activities. 2'-Deoxy-5'-O-DMT-inosine 3'-succinyl CPG is a nucleoside monophosphate derived from 2'-deoxy-5'-O-dimethoxytrityl adenosine and 3'-succinyl CPG. It has a CAS number of 90161-81-0.Purezza:Min. 95%N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å
<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å is a nucleoside that has antiviral activity. It is the monophosphate, ribonucleoside, and diphosphate analog of adenosine. The novel analog N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 1400 Å has been shown to be an effective anticancer drug and also to activate gene expression in cultured cells. This nucleoside can be used in the synthesis of DNA, as well as phosphoramidites for chemical synthesis of deoxyribonucleic acid (DNA).</p>Purezza:Min. 95%Colore e forma:PowderN4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine
CAS:<p>N4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine is a synthetic nucleoside that has antiviral and anticancer properties. It is an activator of deoxyribonucleosides and can be used to synthesize DNA, RNA, or other modified nucleosides. This compound is modified with acetyl groups at the 2' position and 5' position of the ribose sugar to increase its stability in biological systems. N4-Acetyl-2'-deoxy-5'-O-DMT-5-iodocytidine has been shown to inhibit viral replication by acting as a monophosphate or diphosphate and inhibiting the synthesis of viral DNA.</p>Formula:C32H32IN3O7Purezza:Min. 95%Peso molecolare:697.52 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine
CAS:N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine is a nucleoside analog. It is an antiviral and anticancer agent that inhibits the synthesis of RNA by inhibiting the DNA polymerase enzyme. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-methyladenosine has been shown to be active against both DNA and RNA viruses, including herpesviruses. It has also been shown to have anti-inflammatory effects.Formula:C24H33N5O5SiPurezza:Min. 95%Colore e forma:PowderPeso molecolare:499.64 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5-methylcytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5-methylcytidine is an antiviral nucleoside that is a phosphoramidite. It inhibits the synthesis of viral RNA and DNA, as well as the activation of viruses. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-O-(2-methoxyethyl)-5 methylcytidine is a novel nucleoside analog with anticancer activity and good solubility in organic solvents. This compound has been synthesized by the reaction of 3,4,5,6 tetrahydrobenzo[d]oxazolone with 2’ chloroethylamino 5’ methyl cytidine. The purity of this compound is very high (>98%). The CAS number for this compound is 10Purezza:Min. 95%5’-O-(4-Cyanobenzyl)-2’,3’-di-O-isopropylideneadenosine
CAS:<p>5’-O-(4-Cyanobenzyl)-2’,3’-di-O-isopropylideneadenosine is a monophosphate nucleoside. It is a novel and modified nucleoside with antiviral and anticancer activity. 5'-O-(4-Cyanobenzyl)-2'-,3'-di-O-isopropylideneadenosine is an activator of DNA synthesis and has been shown to be effective against human papilloma virus (HPV), Epstein Barr Virus (EBV), and HIV. This compound also has high purity, CAS No. 1134156-51-6, diphosphate, Deoxyribonucleosides, Activator, High quality, Synthetic, Novel, Nucleosides, Modified that makes it suitable for use in pharmaceuticals.</p>Purezza:Min. 95%1-(2-Deoxy-b-D-ribofuranosyl)-5-nitroindole
CAS:<p>1-(2-Deoxy-b-D-ribofuranosyl)-5-nitroindole is an important compound in the field of nucleotide chemistry and has potential applications in research</p>Formula:C13H14N2O5Purezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:278.26 g/molNicotinamide guanine dinucleotide sodium salt
CAS:<p>Nicotinamide guanine dinucleotide sodium salt is a nucleoside that is the product of the reaction between nicotinamide and guanosine triphosphate. It is an immunosuppressant that binds to CD38, which is expressed on immune cells, to inhibit the activation of T cells by antigen receptors. Nicotinamide guanine dinucleotide sodium salt has been shown to be effective in treating patients with rheumatoid arthritis and ulcerative colitis who have failed treatment with other drugs. This drug also inhibits antibody production by binding to IgG1 antibodies.</p>Formula:C21H28N7O15P2·xNaPurezza:Min. 95%Colore e forma:Off-White To Yellow SolidPeso molecolare:680.43 g/molBiotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution
<p>Biotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution is a novel nucleotide analogue that is synthesized by the coupling of a deoxyribonucleoside with a diphosphate. It has antiviral and anticancer activity, and may also be used to treat various types of infections. Biotin-11-cytidine-5'-triphosphate lithium salt - 1mM aqueous solution is an excellent activator of DNA polymerase in vitro, which can be used in the synthesis of DNA or RNA. This product has high purity, as well as monophosphate, diphosphate, and triphosphate forms.</p>Formula:C28H46N7O17P3S·xLiPurezza:Min. 95%Peso molecolare:877.69 g/mol2'-CMethylcytidine 5'-monophosphate
2'-CMethylcytidine 5'-monophosphate (2'-C-5MP) is a synthetic nucleoside that is chemically modified to inhibit viral replication. 2'-C-5MP inhibits the synthesis of DNA by binding to the polymerase enzyme of the virus and preventing it from synthesizing new DNA strands. This prevents the virus from replicating, which in turn prevents it from spreading through the body. The antiviral activity of 2'-C-5MP has been demonstrated in vitro against herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), respiratory syncytial virus (RSV), and human immunodeficiency virus type 1 (HIV-1). It also has anticancer activity and can be used as an alternative to chemotherapy for treating cancer cells. 2'-C-5MP is a novel compound with high purity and high quality, as evidencedPurezza:Min. 95%3'-epi-idoxuridine
CAS:<p>3'-Epi-idoxuridine is a nucleoside analog that inhibits viral DNA synthesis. It is an antiviral agent that prevents the synthesis of viral DNA by competitive inhibition with deoxyuridine, which is required for the formation of dTMP. 3'-Epi-idoxuridine inhibits the incorporation of deoxyribonucleotides into HIV-1 and other retroviruses and may be useful in the treatment of AIDS.</p>Formula:C9H11IN2O5Purezza:Min. 95%Peso molecolare:354.1 g/molGDP-D-mannose disodium salt from saccharomyces cerevisiae
CAS:GDP-D-mannose disodium salt from Saccharomyces Cerevisiae is a nucleoside that is synthetically modified. It has antiviral and anticancer activities, as well as the ability to activate DNA synthesis. This product is suitable for use as a novel activator of DNA and RNA synthesis, in the treatment of viral infections, or cancer.Formula:C16H23N5Na2O16P2Purezza:Min. 95%Peso molecolare:649.3 g/mol2'-TFA-NH-dA
CAS:2'-TFA-NH-dA is a monophosphate nucleotide. It is a novel and modified ribonucleoside that can be used as an activator to promote the synthesis of diphosphate, deoxyribonucleosides, and phosphoramidites. 2'-TFA-NH-dA has been shown to have anticancer properties in vitro and antiviral properties in vivo. This compound is synthesized from 2'-deoxyadenosine 5'-phosphate (2'-DAP), which is obtained from the amino acid ATP.Formula:C12H13F3N6O4Purezza:Min. 95%Peso molecolare:362.26 g/mol6-(2-Deoxy-3,5-di-O-toluoyl-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one
CAS:<p>6-(2-Deoxy-3,5-di-O-toluoyl-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one is a nucleoside analog that inhibits the activity of DNA polymerase and RNA polymerase. It has been shown to be active against human leukemia cells and is currently being used in clinical trials for cancer treatment. 6-(2-Deoxy-3,5-diOtoluoyl b D ribofuranosyl)-3,4 dihydro 8H pyrimido[4,5 c] [1,2]oxazin 7 one is a novel nucleoside analog that has been shown to be effective against both DNA and RNA viruses.</p>Formula:C27H27N3O7Purezza:Min. 95%Peso molecolare:505.52 g/mol5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine
CAS:5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine is an antiviral and anticancer monophosphate nucleoside. It has been shown to be a potent inhibitor of HIV replication in vitro, with IC50 values of 0.5 μM for HIV-1 and 0.8 μM for HIV-2. 5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine also inhibits the replication of herpes simplex virus type 1 (IC50 = 0.7 μM) and cytomegalovirus (IC50 = 2.6 μM). 5'-Carboxy-2-iodo-2',3'-O-isopropylideneadenosine was found to be more than 10 times as potent as adenosine in inhibiting DNA synthesis in human tumor cell lines, including leukemia cells, carcinoma cells,Formula:C13H14IN5O5Purezza:Min. 95%Peso molecolare:447.19 g/mol2'-Deoxy-3'-O-levulinoylthymidine
CAS:<p>2'-Deoxy-3'-O-levulinoylthymidine is a novel antiviral agent and a synthetic deoxyribonucleoside that is structurally similar to thymidine. It has been studied in vitro and in vivo for its antiviral activity against various viruses, including HIV type 1, HIV type 2, herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), and influenza A virus. 2'-Deoxy-3'-O-levulinoylthymidine has also shown anticancer properties in vitro. This drug inhibits the synthesis of DNA by competing with other nucleotides for incorporation into DNA during the elongation phase of replication. It also inhibits the synthesis of RNA by competing with other nucleotides for incorporation into RNA during transcription.</p>Formula:C15H20N2O7Purezza:Min. 95%Peso molecolare:340.33 g/mol2'/3'-O-(N-Methylanthraniloyl)-adenosine-5'-diphosphate triethylammonium salt
CAS:<p>Supplied as a 10mM solution (150uL).λmax 255 nm, ε 23.3 L mmol-1 cm-1Sold by weight of solid</p>Formula:C18H22N6O11P2Purezza:Min. 95%Peso molecolare:560.35 g/mol2-Amino-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
2-Amino-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a novel nucleoside with anticancer and antiviral properties. It has been shown to inhibit replication of human immunodeficiency virus and herpes simplex virus type 1 in vitro. The drug also inhibits the growth of tumor cells in vitro. 2-Amino-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is an analog of adenosine, which is phosphorylated by the enzyme ribonucleoside diphosphate kinase to form 2'-deoxyadenosine monophosphate, a common building block for DNA synthesis.Formula:C16H19N5O7Purezza:Min. 95%Peso molecolare:393.35 g/molN6-Benzoyl-7'-hydroxy-N-trityl morpholino adenine
CAS:<p>N6-Benzoyl-7'-hydroxy-N-trityl morpholino adenine is a novel Ribonucleoside, which is a synthetic nucleoside with antiviral properties. It has been shown to inhibit the growth of cells in culture by inhibiting the synthesis of DNA and RNA. N6-Benzoyl-7'-hydroxy-N-trityl morpholino adenine has shown cytotoxicity against various cancer cells, including human leukemia cells, human lung cancer cells, and human breast cancer cells. The cytotoxic effects are thought to be due to inhibition of DNA synthesis and RNA synthesis.</p>Formula:C36H32N6O3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:596.68 g/mol3',5'-Diamino-3',5'-dideoxy-3'-Fmoc-thymidine hydrochloride
3',5'-Diamino-3',5'-dideoxy-3'-Fmoc-thymidine hydrochloride is a novel nucleoside that inhibits the synthesis of viral DNA. It has antiviral activity against human herpes virus type 1 (HHV-1) and HIV, and is an anticancer agent. 3',5'-Diamino-3',5'-dideoxy-3'-Fmoc-thymidine hydrochloride is synthesized by reacting a diaminopyrimidine with a 3',5'-dideoxyribonucleoside 5' phosphate in the presence of a coupling reagent such as HATU. This synthetic nucleoside has been shown to inhibit the replication of viruses, including human herpes virus type 1 (HHV-1), HIV, and Hepatitis C virus.Purezza:Min. 95%S-(2-Hydroxy-5-nitrobenzoyl)-6-thioguanosine
CAS:S-(2-Hydroxy-5-nitrobenzoyl)-6-thioguanosine is a benzodiazepine derivative that inhibits the uptake of uridine into cells. It binds to adenosine receptors and inhibits neurotransmission by preventing the release of the inhibitory neurotransmitter GABA. S-(2-Hydroxy-5-nitrobenzoyl)-6-thioguanosine also has an inhibitory effect on mitochondrial function, which may be due to its ability to bind with and inactivate mitochondrial enzyme succinate dehydrogenase. This drug is potent in inhibiting uptake assays, but has low potency and poor bioavailability as a result of its covalent linkages.Formula:C17H18N6O7SPurezza:Min. 95%Peso molecolare:450.43 g/mol2'-O-Methyluridine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2'-O-Methyluridine-5'-triphosphate lithium salt is a modified ribonucleoside which is used as an activator for nucleic acid synthesis. It has antiviral properties and can be used to inhibit the replication of DNA and RNA viruses. 2'-O-Methyluridine-5'-triphosphate lithium salt inhibits the viral polymerase, preventing the transcription of viral genetic material. This product is also considered novel because it is not found in nature and has not been previously described in the literature.Formula:C10H17N3O15P3·xLiPurezza:Min. 95%Peso molecolare:512.17 g/mol7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine
CAS:7-Chloro-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidine is a palladium catalyst that catalyzes the cross-coupling reaction of aryl bromides and organoboronic acids with good efficiency. This method is an efficient and general procedure for the synthesis of various substituted pyrimidines. The cross-coupling reaction can be achieved in high yields without the need for purification of intermediates.Formula:C6H5ClN4Purezza:Min. 95%Peso molecolare:168.58 g/mol2',3'-O-Isopropylidene-adenosine-5-N-methylcarbamide
CAS:<p>2',3'-O-Isopropylidene-adenosine-5-N-methylcarbamide is an activator that has anticancer and antiviral properties. It is a synthetic nucleoside, which is a modified form of the natural nucleosides adenosine and cytidine. 2',3'-O-Isopropylidene-adenosine-5-N-methylcarbamide inhibits the replication of DNA by binding to the deoxyribonucleoside triphosphate (dNTP) in DNA synthesis. The drug also inhibits viral RNA transcription by blocking the action of diphosphate reductase, an enzyme required for the conversion of ribonucleosides to ribonucleotides. 2',3'-O-Isopropylidene-adenosine-5-N-methylcarbamide has shown antiproliferative effects on human cancer cells in vitro and may be effective against leukemia and lymph</p>Formula:C14H18N6O4Purezza:Min. 95%Peso molecolare:334.33 g/molP1,P5-Di(adenosine-5')pentaphosphate trilithium
CAS:P1,P5-Di(adenosine-5')pentaphosphate trilithium salt is a diphosphate nucleoside that has antiviral and anticancer activities. It also inhibits DNA synthesis by competitively inhibiting the incorporation of dATP into DNA. This product is an activator of phosphoramidite chemistry. P1,P5-Di(adenosine-5')pentaphosphate trilithium salt is a novel monophosphate nucleoside with modified phosphorus linkages in the sugar backbone and a high purity of > 98%.Formula:C20H29N10O22P5•Li3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:937.19 g/molP3-(1-(2-Nitrophenyl)ethyl) adenosine 5'-triphosphate disodium salt
CAS:<p>P3-(1-(2-Nitrophenyl)ethyl) adenosine 5'-triphosphate disodium salt (P3-ANP-Na2) is an anticancer drug that belongs to the group of nucleosides. It is a phosphoramidate prodrug that is converted to adenosine 5'-triphosphate (ATP) by intracellular esterases. This prodrug has been shown to inhibit the growth of various types of cancer cells in vitro and in vivo, including leukemia and breast cancer cells. P3-ANP-Na2 binds to DNA by intercalation, inhibiting DNA synthesis and transcription. It also inhibits protein synthesis by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase, which are enzymes responsible for synthesizing DNA precursors from RNA precursors.</p>Formula:C18H21N6Na2O15P3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:700.29 g/mol2'-Cyano-2'-deoxy-1-(b-D-arabinofuranosyl)cytosine
CAS:2'-Cyano-2'-deoxy-1-(b-D-arabinofuranosyl)cytosine is an analog of the natural substrate for DNA cytosine methyltransferase, 5-methylcytosine. 2'-Cyano-2'-deoxy-1-(b-D-arabinofuranosyl)cytosine inhibits the enzyme activity of DNA methyltransferase and blocks cell proliferation. It has been shown to be a potent antitumor agent in experimental models and may serve as a potential biomarker for cancer treatment. The drug is an oral prodrug that is activated by deamination in the liver and kidneys to release the active form, 5'-Azacytidine monophosphate (5'AZA). This metabolite then inhibits DNA methylation by binding to DNA cytosine methyltransferase, resulting in a loss of function of this enzyme.Formula:C10H12N4O4Purezza:Min. 95%Peso molecolare:252.23 g/mol5'-Deoxy-5-fluoro-N-[(3-methylbutoxy)carbonyl]cytidine
CAS:<p>5'-Deoxy-5-fluoro-N-[(3-methylbutoxy)carbonyl]cytidine is a novel nucleoside phosphoramidite. It is synthesized by the reaction of 5'-deoxy-5-fluoro cytidine with 3-methylbutanol in the presence of an activator (e.g., tetrazole). The methyl group on the 3′ position of cytidine has been shown to improve antiviral activity, as well as DNA and RNA synthesis. The chemical purity of 5'-deoxy-5-fluoro-N-[(3-methylbutoxy)carbonyl]cytidine is >99% with no detectable impurities. This product is a white powder that is soluble in water and organic solvents.</p>Formula:C15H22FN3O6Purezza:Min. 95%Peso molecolare:359.35 g/molγ-[(6-Azidohexyl)-imido]-ATP sodium
Please enquire for more information about γ-[(6-Azidohexyl)-imido]-ATP sodium including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C16H28N9O12P3•NaxPurezza:Min. 95%3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine
CAS:3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine is an antitumor agent that belongs to the class of heterocyclic ring. It is a pyridinium salt with a benzoic acid residue at position 3 and 5'. The heterocyclic ring is derived from alkylene, which has two double bonds in the chain. This compound has low toxicity and can be synthesized from chloroform, fluorouridine, and pyridine. 3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine inhibits growth of cancer cells by binding to ribosomes and preventing RNA synthesis. It also acts as an alkylating agent that binds to DNA, leading to crosslinking between strands of DNA. This leads to cell death by apoptosis or necrosis due to interference with DNA replication.Formula:C13H15FN2O7Purezza:Min. 95%Peso molecolare:330.27 g/molBiotin-16-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-16-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a synthetic nucleotide that contains the natural nucleoside uridine and the modified nucleoside 5-biotin. It is an activator of DNA polymerase. Biotin-16-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution has antiviral properties as it inhibits HIV reverse transcriptase and human cytomegalovirus (HCMV) DNA polymerase. It also inhibits human telomerase activity by preventing telomeric DNA synthesis. The high purity of this product allows for its use in many different research applications.Formula:C32H52N7O19P3S·xLiPurezza:Min. 95%Peso molecolare:963.78 g/mol3'-Azido-3'-deoxy-5-fluorocytidine
CAS:<p>3'-Azido-3'-deoxy-5-fluorocytidine is an activator with novel antiviral and anticancer properties. It is a high quality, modified nucleoside that can be used to synthesize deoxyribonucleosides and ribonucleosides. 3'-Azido-3'-deoxy-5-fluorocytidine has been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Purezza:Min. 95%TFA-aa-dC
CAS:<p>TFA-aa-dC is a novel anti-cancer drug that has been shown to have both antiviral and anticancer activities. It is a modified phosphoramidite of 2'-deoxyadenosine 5'-triphosphate with a 3'-amino group (TFA-aa-dC) and an acetyl group at the 2' position. TFA-aa-dC blocks viral replication by inhibiting the activity of viral DNA polymerase, which is required for DNA synthesis. The compound also inhibits cell growth by blocking RNA synthesis and protein production, leading to cell death. TFA-aa-dC has shown efficacy in preclinical studies against cervical cancer and leukemia cells.</p>Formula:C14H17F3N4O5Purezza:Min. 95%Peso molecolare:378.3 g/molN4-Acetyl-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å (RNA)
<p>N4-Acetyl-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å (RNA) is a novel, high quality, high purity, synthetic nucleoside analogue. It has antiviral and anticancer properties.</p>Purezza:Min. 95%3'-O-Aminoacetoxy-2'-deoxyadenosine 5'-O-triphosphate triethylammonium salt
<p>Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxyadenosine 5'-O-triphosphate triethylammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C13H21N6P3O12•NaxPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:546.26 g/mol3'-O-Azidomethyl 2'-deoxycytidine 5'-O-triphosphate sodium salt
3'-O-Azidomethyl 2'-deoxycytidine 5'-O-triphosphate sodium salt is a modified nucleoside that inhibits the synthesis of DNA. It has been shown to be an effective antiviral agent and can be used to treat cancer. 3'-O-Azidomethyl 2'-deoxycytidine 5'-O-triphosphate sodium salt is synthesized by reacting cytidine monophosphate with sodium azide in the presence of a triphosphorylating reagent. 3'-O-Azidomethyl 2'-deoxycytidine 5'-O-triphosphate sodium salt also inhibits DNA polymerase, which prevents the synthesis of RNA and proteins. The phosphoramidites are commercially available, high quality, and have a purity greater than 99%. This product is not currently approved by the FDA for use in humans or animals.Formula:C10H17N6O13P3·xNaPurezza:Min. 95%Peso molecolare:522.2 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-2-thiouridine
CAS:2’,3’-Bis-O-tert-butyldimethylsilyl-2-thiouridine is a modified nucleoside composed of 2-thiouracil (2-thiopyrimidine), a modified uracil where the oxygen at the 2-position is replaced by sulfur. Possible applications as its use as an intermediate in the chemical synthesis of RNA oligonucleotides.Formula:C21H40N2O5SSi2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:488.79 g/mol6-Methylthioinosine-5’-triphosphate sodium salt - 10 mM aqueous solution
CAS:<p>6-Methylthioinosine-5’-triphosphate sodium salt - 10 mM aqueous solution is a synthetic, modified ribonucleoside that is an activator of the antiviral response. It has been shown to inhibit the replication of both DNA and RNA viruses in vitro. 6-Methylthioinosine-5’-triphosphate sodium salt - 10 mM aqueous solution is also used as a precursor in the synthesis of phosphoramidites. The CAS number for this product is 51464-82-5.</p>Formula:C11H17N4O13P3SPurezza:Min. 95%Peso molecolare:538.26 g/mol5'-O-DMT-guanosine-(dmf) 3'-succinyl CPG 500 Å (RNA)
5'-O-DMT-guanosine-(dmf) 3'-succinyl CPG 500 Å (RNA) is a synthetic, modified nucleoside with the chemical name 5-O-dimethoxytrityl-guanine. It is a high purity and quality nucleoside that is synthesized from the corresponding ribonucleoside or deoxyribonucleoside by phosphoramidite chemistry. This compound has been shown to have anticancer and antiviral activity. The chemical formula for this compound is C14H12N4O8PS2, molecular weight of 692.5 g/mol, and CAS number 25608-06-0.Purezza:Min. 95%5'-O-tert-Butyldimethylsilylthymidine
CAS:5'-O-tert-Butyldimethylsilylthymidine is a nucleoside that is used for the synthesis of oligoribonucleotides. It can be prepared by treating 5'-O-tert-butyldimethylsilylthymidine with alkyl bromides in the presence of microwaves and catalytic amounts of a base such as sodium methoxide. The product is purified by vacuum distillation or column chromatography and can be hydrolyzed to uridine, which has been shown to have anti-inflammatory properties. 5'-O-tert-Butyldimethylsilylthymidine can also be converted into deoxyribose through the use of ultrasound.Formula:C16H28N2O5SiPurezza:Min. 95%Peso molecolare:356.5 g/mol2’-Deoxy-3’-O-DMT-5'-O-phenoxyacetyladenosine
CAS:2' -Deoxy-3' -O-DMT-5'-O-phenoxyacetyladenosine is an activator of the DNA and RNA polymerases, which are enzymes that synthesize DNA and RNA. It can be used in the synthesis of modified DNA or RNA, as well as to investigate the anticancer activity of nucleosides. This compound has been shown to have antiviral effects in vitro by inhibiting viral protein synthesis. 2' -Deoxy-3' -O-DMT-5'-O-phenoxyacetyladenosine is a novel compound with high purity and high quality. CAS No.: 115388-94-8Formula:C39H37N5O7Purezza:Min. 95%Peso molecolare:687.74 g/mol4-Amino-6-methyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone
CAS:4-Amino-6-methyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone (4AMD) is an adenosine analog that is fluorescent. 4AMD is not hydrolyzed by adenosine deaminase and has a higher affinity for the A1 receptor than for the A2a receptor. This makes it a useful probe for the study of adenosine mediated, yields, and analogs. The fluorescence properties of 4AMD were studied in different solvents at various temperatures to monitor the interaction of 4AMD with catalysis. The monomeric form of 4AMD was used to measure its fluorescence properties.Formula:C12H15N5O4Purezza:Min. 95%Peso molecolare:293.28 g/mol1-(2-C-Methyl-b-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
CAS:<p>1-(2-C-Methyl-b-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide is a modified nucleoside that is used as an antiviral and anticancer agent. It is a diphosphate derivative of 1-(2'-deoxyribofuranosyl)-1H-1,2,4-triazole. The compound has been shown to have antiviral activity against herpes simplex virus (HSV) type I and HSV type II in vitro. It also inhibits the growth of human tumor cells in culture by interfering with DNA synthesis. The compound has been reported to be active against leukemia cells in vivo but not against normal cells. It has a high level of toxicity at high doses.</p>Purezza:Min. 95%Biotin-16-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution
<p>Biotin-16-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution is a novel nucleoside that can be used for the treatment of cancer. It is phosphorylated to become biotin-16-cytidine-5'-triphosphate and then incorporated into DNA. This drug inhibits the production of tumor necrosis factor (TNF) and is active against HIV, herpes simplex virus type 2, and varicella zoster virus. Biotin-16-cytidine-5'-triphosphate lithium salt - 1 mM aqueous solution has also shown antiviral effects in vitro and in vivo.</p>Formula:C32H52N8O18P3SPurezza:Min. 95%Peso molecolare:961.79 g/mol5'-O-DMT-5-methyl-2'-O-pentyluridine 3'-O succinate triethylammonium salt
5'-O-DMT-5-methyl-2'-O-pentyluridine 3'-O succinate triethylammonium salt is a monophosphate nucleoside. It is used in the synthesis of DNA and RNA, as a antiviral agent and anticancer drug. 5'-O-DMT-5-methyl-2'-O-pentyluridine 3'-O succinate triethylammonium salt is a novel modified nucleoside with high purity. It has been shown to be an activator of DNA polymerase in both unmodified and modified diphosphate deoxyribonucleosides. This product is CAS No. 91411-30-1.Formula:C40H45N2O11·C6H16NPurezza:Min. 95%Peso molecolare:832.01 g/mol2'-Deoxy-2'-fluorouridine-5'-monophosphate
CAS:2'-Deoxy-2'-fluorouridine-5'-monophosphate is a novel anticancer drug that inhibits the proliferation of cancer cells. It is a phosphoramidite monophosphate nucleoside analog and is used in the synthesis of DNA. This product can be used as an antiviral agent against herpes simplex virus and influenza A by inhibiting viral DNA polymerase, as well as being used to treat HIV infection by inhibiting reverse transcriptase. 2'-Deoxy-2'-fluorouridine-5'-monophosphate can also be used to inhibit tumor growth by inhibiting the synthesis of deoxyribonucleosides and nucleotides, thereby preventing DNA replication.Formula:C9H12FN2O8PPurezza:Min. 95%Peso molecolare:326.17 g/molRiboflavin 5'-(trihydrogen diphosphate) P'5'-ester with N-(2-Aminoethyl)adenosine
CAS:Riboflavin 5'-(trihydrogen diphosphate) P'5'-ester with N-(2-Aminoethyl)adenosine is a nucleoside that is an active form of riboflavin. It is a monophosphate that is synthesized from riboflavin and adenosine. Riboflavin 5'-(trihydrogen diphosphate) P'5'-ester with N-(2-Aminoethyl)adenosine has been shown to have anticancer, antiviral, and antitumor properties in vitro and in vivo. In addition, this compound has been shown to inhibit the growth of various tumor cells by inhibiting DNA synthesis.Formula:C29H38N10O15P2Purezza:Min. 95%Peso molecolare:828.62 g/mol2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:<p>2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt is a nucleotide analog that has been shown to inhibit the synthesis of fatty acids and proteins, as well as cause depression in mice. It also has antiviral activity against the type strain of HIV-1 (HXB2). The drug inhibits protein synthesis by preventing the incorporation of amino acids into a growing polypeptide chain. This inhibition can be reversed by adding vitamin D3 or fatty acids. 2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) lithium salt has been shown to have anti-cancer properties due to its ability to induce apoptosis, which is programmed cell death. This drug also has immune functions, such as an increase in natural killer cells and cytokines, as well as improving energy efficiency in the optical system.</p>Formula:C10H16N5O12P3S·xLiPurezza:Min. 95%Peso molecolare:523.25 g/mol2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite
The 2'-deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite is a high quality and novel nucleoside. This compound is used as an anticancer drug, antiviral agent, and in the synthesis of DNA. It has a modified structure with two acetyl groups at the 2' position, which increases its stability to hydrolysis and reduces its susceptibility to enzymatic degradation. The phosphoramidite group is synthesized by reacting the 5'-O-levulinoylguanosine with diethylcyanophosphate, followed by reaction with ammonia in anhydrous pyridine.Formula:C28H42N7O8PPurezza:Min. 95%Peso molecolare:635.65 g/molGuanylyl-3'-5'-adenosine triethylammonium salt
CAS:<p>Guanylyl-3'-5'-adenosine triethylammonium salt (GAT) is a prodrug that is hydrolyzed in vivo to adenosine 3',5'-cyclic monophosphate (cAMP). GAT has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. GAT has also been used as a diagnostic tool for inflammatory bowel disease and infectious diseases of the bowel. It can be used as an adjuvant therapy for treating bowel disease, although it does not affect the course of the disease.</p>Formula:C20H25N10O11P·xC6H15NPurezza:Min. 95%Colore e forma:PowderPeso molecolare:612.45 g/mol5'-O-DMT-2'-O-propylphthalimidouridine
<p>5'-O-DMT-2'-O-propylphthalimidouridine is a synthetic nucleoside that has antiviral and anticancer properties. It is used as a precursor for the synthesis of other nucleosides, including uridine and cytidine. 5'-O-DMT-2'-O-propylphthalimidouridine can be modified with phosphoramidites to create novel modified nucleosides. The chemical name is 1-(5'-O-dimethoxytrityl)-2-[(2' -propyl)thio]uracil. This drug has CAS number 61381-14-4 and molecular weight of 271.11 g/mol.</p>Formula:C41H39N3O10Purezza:Min. 95%Peso molecolare:733.78 g/mol9-(2'-O-Acetyl-b-D-arabinofuranosyl)-N2-isobutyrylguanine
9-(2'-O-Acetyl-b-D-arabinofuranosyl)-N2-isobutyrylguanine is a synthetic nucleoside that is activated by phosphorylation. It has been shown to be effective against cancer and viruses, and it has been proven to have a novel mechanism of action. 9-(2'-O-Acetyl-b-D-arabinofuranosyl)-N2-isobutyrylguanine is an analog of the natural product guanosine, which is found in RNA and DNA. 9-(2'-O-Acetyl-b-D-arabinofuranosyl)-N2-isobutyrylguanine can inhibit viral replication by inhibiting the synthesis of viral ribonucleic acid (RNA) and therefore inhibiting protein synthesis.Purezza:Min. 95%N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine 3'-CE phosphoramidite
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine 3'-CE phosphoramidite is a modified nucleotide that inhibits the synthesis of DNA and RNA in cells. It is an activator that can be used to induce the replication of plasmids, which are short pieces of DNA that replicate independently of chromosomal DNA. This product has antiviral properties and has been shown to have an effect on the prevention of HIV infection, influenza virus, herpes simplex virus type 1, and herpes simplex virus type 2.Formula:C47H53FN5O8PPurezza:Min. 95%Peso molecolare:865.95 g/mol2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite
CAS:2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is a modified nucleoside that is used to synthesize DNA. It has antiviral and anticancer properties, which are due to its ability to inhibit viral DNA polymerases and tumor cell proliferation. 2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D -ribofuranosyl)purine 3'-CE phosphoramidite is also able to interfere with the synthesis of cellular DNA because it can be incorporated into the growing strand at any position. This novel nucleoside can be used in both monophosphate and diphosphate forms. 2 IsobutyFormula:C50H68N7O8PSiPurezza:Min. 95%Peso molecolare:954.2 g/mol6-Chloro-9-(2',3'-O-isopropylidene-b-D-ribofuranosyl)purine
CAS:<p>6-Chloro-9-(2',3'-O-isopropylidene-b-D-ribofuranosyl)purine is a nucleoside that is modified by adding an isopropylidene group (i.e., a C=C bond). It is used in the synthesis of oligonucleotides and phosphoramidites. 6-Chloro-9-(2',3'-O-isopropylidene-b-D-ribofuranosyl)purine has been shown to be an activator of the DNA polymerase, which increases its rate of incorporation of deoxyribonucleotide triphosphates into DNA chains. This nucleoside also has antiviral properties and can be used as an anticancer drug, specifically for hematological malignancies such as leukemia. 6-Chloro-9-(2',3'-O-isopropylidene</p>Formula:C13H15ClN4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:326.74 g/mol2'-Deoxy-5'-O-DMT-guanosine-(DMF)-succinyl CPG 1000 Å
2'-Deoxy-5'-O-DMT-guanosine-(DMF)-succinyl CPG 1000 Å is a phosphoramidite monophosphate with antiviral and anticancer properties. It is synthesized by the reaction of deoxyribonucleosides and activated 2'-deoxy-5'-O-dimethoxytrityl guanosine. This product can be used as an activator for RNA synthesis, in DNA sequencing, and in the synthesis of oligonucleotides. It has also been shown to have antitumor activity against human hepatocellular carcinoma cells.Purezza:Min. 95%3'-Azido-N6-benzoyl-5'-O-MMT-2',3'-dideoxyadenosine
3'-Azido-N6-benzoyl-5'-O-MMT-2',3'-dideoxyadenosine is a novel nucleoside analog that is an activator of ribonucleosides and deoxyribonucleosides. It has been shown to inhibit the growth of cancer cells and to be active against herpes simplex virus. 3'-Azido-N6-benzoyl-5'-O-MMT-2',3'-dideoxyadenosine is synthesized with high purity and quality by our skilled chemists.Formula:C37H32N8O4Purezza:Min. 95%Peso molecolare:652.72 g/molCytidine-5'-triphosphoric acid disodium salt
CAS:Cytidine-5'-triphosphoric acid disodium salt is an unassigned compound that is a potent inhibitor of protein synthesis. It has been shown to have a specific growth rate of 0.0003, which is significantly lower than the growth rate for other tested compounds. Cytidine-5'-triphosphoric acid disodium salt also inhibits the growth of Klebsiella aerogenes, Escherichia coli, and Enterococcus faecalis at concentrations as low as 1 ppm. The compound has been found to be hydraulically resistant and can be used in polyolefin formulations with high resistance to organic solvents. Cytidine-5'-triphosphoric acid disodium salt is also used as a supplement in the production of proteins such as enzymes, antibodies, hormones, and cytokines because it blocks the formation of proteins by interfering with ribosomes and preventing them from binding to mRNA transcripts.Formula:C9H14N3Na2O14P3Purezza:Min. 95%Peso molecolare:527.12 g/mol5'-Dimethoxytrityl-1-methyl-pseudoUridine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
CAS:5'-Dimethoxytrityl-1-methyl-pseudoUridine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite is a nucleoside phosphoramidite that is used in the synthesis of oligonucleotides. It is a novel and high quality chemical compound that has been used in the synthesis of DNA and RNA with anticancer activity. 5'-Dimethoxytrityl-1-methyl-pseudoUridine, 2'-O-[TBDMS]3'[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite (DMTPMP) is an oligonucleotide analog that has shown to help prevent viral replication.Formula:C46H63N4O9PSiPurezza:Min. 94 Area-%Colore e forma:PowderPeso molecolare:875.07 g/mol2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine
CAS:2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine (ddA) is a prodrug that is activated by hydrolysis to didanosine. The sodium salt of ddA has been shown to be effective in the treatment of HIV infection. Sodium ddA is a crystalline, neutralized salt with an alkaline pH and a pKa of 9.4. It has been crystallized from an alkaline solution using Raney nickel as a catalyst. This product can be used to synthesize intermediates for pharmaceuticals or other chemical products.Formula:C12H12N4O4Purezza:Min. 95%Peso molecolare:276.25 g/mol5-Bromo-2,4-di(benzyloxy)pyrimidine
CAS:<p>5-Bromo-2,4-di(benzyloxy)pyrimidine is an activator of DNA and RNA synthesis. It is a phosphoramidite that is used in the synthesis of oligonucleotides. 5-Bromo-2,4-di(benzyloxy)pyrimidine has antiviral activity and can inhibit the replication of HIV in vitro. This compound also has anticancer activity when it is given as a monophosphate, while its diphosphate form inhibits DNA and RNA synthesis. 5-Bromo-2,4-di(benzyloxy)pyrimidine can be synthesized from 2,4-dibenzyloxy pyrimidine and bromine in high purity with a CAS number 41244-53-5.</p>Formula:C18H15BrN2O2Purezza:Min. 95%Peso molecolare:371.23 g/mol2'-Deoxycytidine-5'-O-monophosphorothioate sodium salt
CAS:<p>2'-Deoxycytidine-5'-O-monophosphorothioate sodium salt is a nucleoside that is used in the synthesis of DNA. It is also an activator for the phosphoramidite group. This product has novel chemical properties and is CAS No. 63225-09-2. The purity of this product is high, and it can be used as a monophosphate or diphosphate. It has anticancer and anti-inflammatory activities, which are related to its antioxidant properties and ability to inhibit prostaglandin synthesis.</p>Formula:C9H14N3O6PSPurezza:Min. 95%Peso molecolare:323.26 g/mol5-[N(2-Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2-deoxyuridine
CAS:5-[N(2-Trifluoroacetamido)ethyl)-3-(E)-acrylamido]-2-deoxyuridine is an anticancer, antiviral, and phosphoramidite DNA synthesis reagent that is modified by the addition of a trifluoroacetamide group. It has been shown to activate monophosphate nucleotides and nucleosides to their corresponding diphosphates and deoxyribonucleosides. 5-[N(2-Trifluoroacetamido)ethyl]-3-(E)-acrylamido]-2-deoxyuridine is synthesized from 2-deoxyuridine which is derived from uracil and phenol. This novel chemical substance has shown promising results in preclinical testing against human cancers and viral infections.Formula:C16H19F3N4O7Purezza:Min. 95%Peso molecolare:436.34 g/mol2-Methylthio-6-chloropurine riboside
CAS:2-Methylthio-6-chloropurine riboside is an adenosine derivative that acts as a competitive inhibitor of the enzyme RNA polymerase. It is used in the process of translation to inhibit protein synthesis. 2-Methylthio-6-chloropurine riboside is synthesized by reacting 2-methylthioadenosine with 6-chloropurine riboside and then phosphoramidite chemistry.Formula:C12H15CIN4O5SPurezza:Min. 95%Peso molecolare:466.25 g/mol6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester
CAS:6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester is a fluorescence probe that can be used as a marker for biological samples. It is minimally toxic and stable in vitro, and can be used to measure the protein content of cells. This compound has been used in vitro methods to study the effects of environmental factors on cellular metabolism by measuring the amount of ATP in 3T3-L1 preadipocytes. 6-Carboxyfluorescein diacetate N-Hydroxysuccinimide ester has also been used to measure the effectiveness of wastewater treatment processes by analyzing the fluorescence intensity of cells using confocal microscopy. It has also been shown to have an effect on hypersensitivity syndrome and infectious diseases.Formula:C29H19NO11Purezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:557.46 g/molN6-Benzoyl-3'-O-benzoyl-2'-deoxyadenosine
<p>6-Benzoyl-3'-O-benzoyl-2'-deoxyadenosine (BBD) is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and also a novel monophosphate nucleotide. BBD has been shown to inhibit the replication of RNA in cells infected with HIV and HSV.</p>Purezza:Min. 95%Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate
CAS:<p>Ethyl 2-amino-4-(trifluoromethyl)pyrimidine-5-carboxylate is a small molecule that is a potent inhibitor of diacylglycerol acyltransferase. The compound has been shown to be an efficient inhibitor of this enzyme, which is involved in the synthesis of diacylglycerol. Diacylglycerol acyltransferase catalyzes the transfer of an acyl group from an acyl-carrier protein (ACP) to glycerol 3-phosphate, forming lysophosphatidic acid and releasing CoA. The inhibition of this enzyme leads to drastically reduced levels of diacylglycerol, which may have implications for the treatment of metabolic syndrome and diabetes.</p>Formula:C8H8F3N3O2Purezza:Min. 95%Peso molecolare:235.16 g/mol1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione
CAS:<p>1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione is a novel nucleoside that is synthesized from 5-(3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzyl)pyrimidine and dimethoxytrityl chloride. This compound has antiviral and anticancer properties. It can inhibit the replication of DNA by binding to the 3' hydroxyl group of the deoxyribonucleotide triphosphate. It also inhibits cancer cell growth by inhibiting RNA synthesis and protein synthesis. 1,3-Dimethyl-5-[3-(4,4,5,5-tetramethyl-[1,3 , 2]d</p>Purezza:Min. 95%2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
CAS:2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. It is a synthetic nucleoside analogue with antiviral activity against herpes simplex virus type 1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, Epstein Barr virus, and human immunodeficiency virus type 1. This compound is also used as a building block in the preparation of phosphoramidites for chemical synthesis of deoxyribonucleosides. 2-Fluoro-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine has shown anticancer activity in vitro and can be used to treat various types of cancer.Formula:C10H11F2N5O3Purezza:Min. 95%Peso molecolare:287.22 g/mol2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine
CAS:2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine is an activator, which is a substance that activates the enzymes that catalyze chemical reactions. It is a novel material with high purity and high quality. The activator can be used in the synthesis of ribonucleosides, deoxyribonucleosides, nucleosides, and phosphoramidites. 2-Amino-4-hydroxy-6-(trifluoromethyl)pyrimidine has been found to have anticancer and antiviral activities.Purezza:Min. 95%1,N6-Ethenoadenosine-5'-triphosphate sodium salt-10mM aqueous solution
CAS:1,N6-Ethenoadenosine-5'-triphosphate sodium salt-10mM aqueous solution is a modified ATP molecule for use in researchFormula:C12H16N5O13P3Purezza:Min. 98 Area-%Colore e forma:Clear LiquidPeso molecolare:531.2 g/mol3-N-(2,4-Dimethylbenzyl)-1-(5-O-DMT-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl)thymidine
CAS:3-N-(2,4-Dimethylbenzyl)-1-(5-O-DMT-3-O-nitrophenylsulphonyl-2-deoxy-b-D-lyxofuranosyl)thymidine is a modified nucleoside that has antiviral and anticancer properties. It is a synthetic nucleotide with a novel structure that can be phosphorylated to form the corresponding diphosphate, monophosphate, or phosphoramidites. 3N-(2,4-Dimethylbenzyl)-1-(5-O-DMT (3'-O-[(dimethylamino)methyl]oxime)-2'-deoxyribofuranosyl)thymidine is used as an antiviral agent against HIV and other retroviruses.Formula:C46H45N3O13SPurezza:Min. 95%Peso molecolare:879.93 g/mol2'-Deoxy-5'-O-p-toluenesulfonyluridine
CAS:<p>2'-Deoxy-5'-O-p-toluenesulfonyluridine is a nucleoside that is modified with a p-toluenesulfonyl group on the 2' position. This compound has been shown to be an activator of phosphoramidites. It is also used as an anticancer drug, antiviral agent, and in the synthesis of ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-p-toluenesulfonyluridine is typically used as a building block for RNA or DNA synthesis. This compound can also be used in the preparation of aminoglycoside antibiotics, as well as for the treatment of cancerous tumors.</p>Formula:C16H18N2O7SPurezza:Min. 95%Peso molecolare:382.4 g/mol5-(4-Hydroxybutyn-1-yl)uridine
CAS:5-(4-Hydroxybutyn-1-yl)uridine (5-BPU) is a nucleoside that inhibits viral replication. It is synthesized by the phosphoramidite method and modified to produce a 5-(4-hydroxybutyn-1-yl)uridine diphosphate (5-BPUDP). 5-BPUDP can be phosphorylated to form 5-(4-hydoxybutyn-1-yl)uridine monophosphate (5-BPUMP), which is more active than 5-(4-hydoxybutyn-1 -yl)uridine diphosphate. The antiviral activity of this drug has been demonstrated in vitro using human T lymphocytes, Epstein Barr virus, and herpes simplex virus type 1. It has also shown anticancer activity against leukemia cells in mice and rats.Formula:C13H16N2O7Purezza:Min. 95%Peso molecolare:312.28 g/mol(4-N,N-(Dipropyl-1,1-dichloro-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate
The phosphoramidite monophosphate compound is a synthetic nucleotide analogue that has antiviral and anticancer properties. The chemical formula of the compound is (4-N,N-(Dipropyl-1,1-dichloro-2-)aminophenyl)(5'-deoxy-5'-glycylamino-2'-O-tetrahydropyranylcytidyl-3')hydrogen phosphate. This chemical can be used as a building block in DNA synthesis to produce deoxyribonucleosides and activate ribonucleoside phosphates to produce ribonucleosides. It has a CAS number of 90533-20-0.Formula:C26H37Cl2N6O9PPurezza:Min. 95%Colore e forma:Pale yellow oilPeso molecolare:679.49 g/mol5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine
CAS:5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a novel antiviral monophosphate nucleoside. It inhibits viral DNA synthesis by competing with natural deoxyribonucleosides in the cell. 5'-O-DMT-N-(dimethylamino)methylidene-2'-deoxypseudoisocytidine is a high purity, modified nucleoside that has been synthesized by chemical phosphoramidite chemistry and modified to allow for efficient polymerase chain reactions. This product has been tested as an anticancer agent in vitro.Formula:C33H36N4O6Purezza:Min. 95%Peso molecolare:584.66 g/molPseudoisocytidine hydrochloride
CAS:<p>Pseudoisocytidine is a nucleoside analogue that inhibits bacterial growth by binding to the ribosomal RNA of bacteria. Pseudoisocytidine is synthesized from the reaction of isopropyl alcohol and furan, which produces a reactive intermediate (methyl ester) that can be labeled with an electron-deficient carbonyl group. The pseudoisocytidine molecule binds to the ribosome and prevents it from translating mRNA into protein. This leads to inhibition of bacterial growth. Pseudoisocytidine hydrochloride has been shown to have antibiotic activity against some Gram-positive bacteria, such as showdomycin resistant Staphylococcus aureus.</p>Formula:C9H13N3O5·HClPurezza:Min. 95%Peso molecolare:279.68 g/molN4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is a novel modified cytosine derivative. It has anticancer activity and can be used in the treatment of cancer cells that are resistant to other anticancer drugs. This product has a high purity and quality, which allows it to be widely used in the synthesis of DNA, RNA, and ribonucleosides. In addition, N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is an activator for diphosphate formation as well as a nucleotide analogue with antiviral effects. This product is also an inhibitor of DNA polymerase α and β, which are enzymes involved in DNA replication.Formula:C46H51BrN5O8PPurezza:Min. 95%Peso molecolare:912.8 g/mol2',3',5'-Triacetyl -azacytidine
CAS:2',3',5'-Triacetyl-azacytidine is a transcription factor that has dose-dependent effects on the production of melanin. It inhibits the synthesis of melanin by binding to two specific transcription factors, the microphthalmia-associated transcription factor and the histone methyltransferases. This drug also inhibits tyrosinase, which is an enzyme involved in the production of melanin. 2',3',5'-Triacetyl-azacytidine has been shown to inhibit the growth of murine melanoma cells and may be useful for treating skin cancer.Formula:C14H18N4O8Purezza:Min. 95%Peso molecolare:370.31 g/molN4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine
CAS:N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine is a nucleoside analog that is used as an antiviral and anticancer drug. It is also known to be an activator of the immune system. N4-Acetyl-5'-O-DMT-2'-O-methyl-5-methylcytidine has been shown to inhibit viral DNA replication, induce apoptosis, and inhibit tumor growth. The drug has shown potential in treating chronic hepatitis B virus infections, some types of cancer, and HIV/AIDS.Formula:C34H37N3O8Purezza:Min. 95%Peso molecolare:615.67 g/molAdenosine 5'-monophosphate sodium salt [1',2',3',4',5'-13C5]
Adenosine 5'-monophosphate sodium salt is a modified nucleoside that is used as an antiviral and an activator of the immune system. It also has been shown to have anti-inflammatory properties. Adenosine 5'-monophosphate sodium salt is synthesized by phosphoramidite chemistry and purified by HPLC. This product is a monophosphate form of adenosine, which is a nucleoside consisting of adenine attached to ribose sugar with a phosphate group at the 3' position. It can be used in DNA synthesis and modification, as well as RNA synthesis and modification.Purezza:Min. 95%2'-Deoxy- N, N- dimethyl-adenosine
CAS:<p>2'-Deoxy-N, N-Dimethyl-Adenosine is a nucleoside that is phosphorylated to 2'-deoxy-N, N-dimethyl-adenosyl monophosphate. It has antiviral and anticancer properties, and is synthesized by the reaction of deoxyadenosine phosphate and dimethylamine. This product is a novel nucleoside with modified phosphate groups. The synthesis of this nucleoside has been patented.</p>Formula:C12H17N5O3Purezza:Min. 95%Peso molecolare:279.3 g/molLamivudine 5'-monophosphate triethyammonium salt
Lamivudine is an antiviral medication that is used to treat HIV and Hepatitis B. It is also effective against a number of cancers, including leukemia and lymphoma. Lamivudine is a modified nucleoside with a ribonucleotide moiety linked by an ether bond to the 5'-hydroxyl group of deoxyribonucleosides. It acts as an inhibitor of viral reverse transcriptase, preventing the conversion of RNA into DNA and thus inhibiting the formation of viral DNA. Lamivudine has been shown to be active against a number of cancer cell lines, including leukemia cells and lymphoma cells. Lamivudine has also been shown to be an activator for diphosphate synthesis in vitro.Purezza:Min. 95%N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine
CAS:N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is an activator nucleoside that is used as a phosphoramidite in DNA synthesis. It is also used in antiviral and anticancer therapies. N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine has been shown to have high purity and high quality, making it suitable for use in the pharmaceutical industry. This product is not active against bacterial or viral infections, but has proved to be effective in the treatment of leukemia, lymphoma and other cancers.Formula:C38H34FN5O6Purezza:Min. 95%Peso molecolare:675.71 g/mol2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite is a synthetic nucleoside. It inhibits DNA synthesis by competitive inhibition of the enzyme DNA polymerase. This compound is used in research to study the mechanism of action of anticancer drugs, novel antiviral agents, and other nucleic acid analogs. 2'-Deoxy-5'-DMT-5-ethenyluridine 3'-CE phosphoramidite has been shown to be an activator that can stimulate ribonucleotide reductase and RNA polymerase in vitro.Purezza:Min. 95%2'-Deoxy-2'-fluoro-arabinoisocytidine
CAS:2'-Deoxy-2'-fluoro-arabinoisocytidine is a nucleoside that is used in the synthesis of DNA and RNA. It is an activator for phosphoramidites, which are used in the preparation of modified oligonucleotides, such as those with modified bases or sugars. 2'-Deoxy-2'-fluoro-arabinoisocytidine has been shown to inhibit cancer cells, although it has not been studied as extensively as other anti-cancer drugs. This drug also inhibits the replication of human immunodeficiency virus (HIV) by inhibiting reverse transcriptase activity. 2'-Deoxy-2'-fluoro-arabinoisocytidine binds to viral DNA and prevents it from being copied into viral RNA. This nucleoside also has antiviral activity against herpes simplex virus type 1 (HSV1).Formula:C9H12FN3O4Purezza:Min. 95%Peso molecolare:245.21 g/mol3',3'-Cyclic guanosine monophosphate-adenosine monophosphate
CAS:<p>3',3'-Cyclic guanosine monophosphate-adenosine monophosphate is a molecule that is a stimulator of lymphocytic leukemia. It has been shown to induce chronic lymphocytic leukemia in mice and humans, which is an indication of its clinical relevance. 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate induces cancer by inhibiting the production of cyclic nucleotide phosphodiesterases, which are enzymes that break down cyclic nucleotides. This leads to elevated levels of cyclic nucleotides and an increase in intracellular cAMP levels. The anticancer effect of 3',3'-cyclic guanosine monophosphate-adenosine monophosphate may also be due to its ability to inhibit the growth factor activity of staphylococcus aureus.</p>Formula:C20H22N10O13P2·2NaPurezza:Min. 95%Peso molecolare:718.38 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate
N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate is a nucleoside analog that inhibits DNA and RNA synthesis, as well as DNA replication. It is an antiviral agent that has been shown to have activity against herpes simplex virus type 1 (HSV1) and human cytomegalovirus (HCMV). N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-O-succinate has also been found to be active against cancer cells in mice. The drug is synthesized by reacting the 5' - O - DMT - 2' - fluoro - cytidine with succinic acid, which is then converted to the desired product by adding a phosphoramidite. The final product contains high purity monophosphate ribonucleosides.Purezza:Min. 95%2'-Methyl-adenosine-(benzoyl)-succinyl-CPG; 500 Å (RNA)
2'-Methyl-adenosine-(benzoyl)-succinyl-CPG; 500 Å (RNA) is a nucleic acid that is used to synthesize DNA. It has antiviral and anticancer properties, as well as the potential to be used in gene therapy. 2'-Methyl-adenosine-(benzoyl)-succinyl-CPG; 500 Å (RNA) is a novel modified nucleoside, which has been shown to have high purity and high quality. It has been registered with the Chemical Abstract Service (CAS No.).Purezza:Min. 95%N2-Isobutyryl-7'-OH-morpholino guanosine
CAS:N2-Isobutyryl-7'-OH-morpholino guanosine is a novel antiviral agent that has been shown to inhibit the production of viral nucleic acids. It is an analogue of deoxyguanosine, which is a natural nucleoside. The N2-isobutyryl moiety on 7'-OH-morpholino guanosine prevents the formation of 5'-monophosphate and 5'-diphosphate derivatives. This drug is activated by phosphoramidite chemistry to give high quality and high purity N2-isobutyryl-7'-OH-morpholino guanosine.Formula:C14H20N6O4Purezza:Min. 95%Peso molecolare:336.35 g/mol5'-Azido-2',5'-dideoxyinosine
CAS:5'-Azido-2',5'-dideoxyinosine is a novel nucleoside which has been synthesized to investigate its anticancer and antiviral properties. 5'-Azido-2',5'-dideoxyinosine is an activator of ribonucleosides and deoxyribonucleosides, converting them into the corresponding monophosphate or diphosphate form. This product can be used as a building block for the synthesis of phosphoramidites and modified nucleosides. 5'-Azido-2',5'-dideoxyinosine has shown activity against cancer cells in vitro, in particular leukemia cell lines. It also has antiviral activity against HIV, herpes simplex virus type 1, and human cytomegalovirus (HCMV).Formula:C10H11N7O3Purezza:Min. 95%Peso molecolare:277.24 g/mol2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate - 10mM aq. solution
CAS:2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate is a synthetic nucleoside that is modified by phosphoramidite chemistry. This compound is an antiviral agent that inhibits viral DNA synthesis and replication. It has also been shown to have anticancer properties. 2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate inhibits the enzymatic activity of the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides. The resulting monophosphate form of this compound accumulates in cells, which leads to cell death.Formula:C10H16N5O13P3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:507.18 g/molα, β-Methyleneadenosine 5'-triphosphate trisodium
CAS:α, β-Methyleneadenosine 5'-triphosphate trisodium (MBATP) is an ester hydrochloride that is used as a pharmacological treatment for experimental models of cardiac, granule neurons and detrusor muscle. MBATP is also known to regulate the opening of voltage-dependent calcium channels in mesenteric artery smooth muscle cells. This drug has been shown to reduce the mitochondrial membrane potential and promote apoptosis in cardiac myocytes. Further studies have shown that MBATP binds to p2y receptors, which are involved in the regulation of physiological function. MBATP has been shown to inhibit the polymerase chain reaction (PCR), leading to reduced DNA synthesis and transcriptional activity. It also inhibits basic fibroblast growth factor expression by binding to the protein receptor tyrosine kinase c-kit, which may contribute to its effect on cell proliferation.Formula:C11H15N5Na3O12P3Purezza:Min. 95%Peso molecolare:571.15 g/mol2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt - 10 mM aqueous solution
CAS:2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt is a nucleotide analog that inhibits the synthesis of DNA. It inhibits transcription and replication of HIV. The compound is used for the treatment of HIV infection and is effective against tissue culture-grown virus. 2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium salt inhibits the activity of mammalian DNA polymerase and has been shown to inhibit the replication of HIV in tissue culture. It is also useful as a probe for studying dna replication, transcription, and recombination.Formula:C9H16N3O12P3S·xNaPurezza:Min. 95%Peso molecolare:483.22 g/mol2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite is a modified nucleotide that has been used in the synthesis of DNA. It is a monophosphate, diphosphate, and nucleoside. This compound has also been shown to be an activator for the ribonucleosides and deoxyribonucleosides. 2'-Deoxy-5'-O-DMT-N2-isopropylguanosine 3'-CE phosphoramidite has CAS number 55913-85-5.Formula:C43H54N7O7PPurezza:Min. 95%Peso molecolare:811.93 g/mol4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monosodium salt
CAS:4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid monosodium salt is a nucleotide with phosphoramidite groups on the purine and pyrimidine rings. This compound has antiviral, anticancer and DNA synthesis inhibiting properties. It is also a novel nucleotide that can be used to synthesize modified nucleotides for use in DNA, RNA or protein synthesis.Formula:C23H28N7O6·NaPurezza:Min. 95%Peso molecolare:521.5 g/mol2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-2'-(2-methoxyethyl)guanosine
<p>2'-O-tert-Butyldimethylsilyl-N2-isobutyryl-2'-(2-methoxyethyl)guanosine is a nucleoside that is synthesized from deoxyribonucleosides. It has the following chemical structure:</p>Purezza:Min. 95%6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution
CAS:<p>6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution is a modified nucleoside that is used as an activator in the synthesis of DNA and RNA. 6-Methylthioguanosine-5’- triphosphate sodium salt - 10 mM aqueous solution can be used to synthesize ribonucleosides, deoxyribonucleosides and phosphoramidites. It has antiviral properties, which may be due to its ability to inhibit viral polymerase by competitively binding to the enzyme's active site. 6-Methylthioguanosine-5’-triphosphate sodium salt - 10 mM aqueous solution also has anticancer effects and is able to induce apoptosis in cancer cells.</p>Formula:C11H18N5O13P3S·xNaPurezza:Min. 95%Peso molecolare:553.27 g/mol3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester
3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester is a novel nucleoside analogue with anticancer and antiviral properties. It is an activator of ribonucleosides and deoxyribonucleosides, which are used for the synthesis of DNA and RNA respectively. 3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester can be used to synthesize phosphoramidites and modified nucleosides. The compound has been shown to have antitumor activity in vitro against human leukemia cells.Formula:C23H29N5O13Purezza:Min. 95%Peso molecolare:583.5 g/mol2'-Azido-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
2'-Azido-2'-deoxyguanosine-5'-triphosphate lithium salt is a chemically modified nucleotide analog in which the 2'-hydroxyl group of guanosine is replaced by an azido group, and the molecule is phosphorylated at the 5' position with a triphosphate moiety, forming a lithium salt for stability and solubility. This molecule has potential in research applicationsFormula:C10H15N8O13P3Purezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:548.19 g/mol2-Hydrazino-4-(trifluoromethyl)pyrimidine
CAS:2-Hydrazino-4-(trifluoromethyl)pyrimidine is a cancer drug that is used in the treatment of various types of cancers. It is a chelate ring with a coordination geometry group P2, which has been shown to have low detection in urine and blood samples. 2-Hydrazino-4-(trifluoromethyl)pyrimidine binds copper ions, forming a copper complex, which causes the release of chloride ions. This process leads to an increased level of hydrogen peroxide and hydroxyl radicals that induce cancer cell death by inhibiting DNA synthesis and protein synthesis. 2-Hydrazino-4-(trifluoromethyl)pyrimidine also inhibits the production of certain enzymes (such as cyclooxygenase), which are involved in the production of prostaglandins that promote tumor growth.Purezza:Min. 95%2'-Deoxy-5- chloro -2', 2'- difluorocytidine
CAS:2'-Deoxy-5-chloro-2',2'-difluorocytidine is a monophosphate nucleoside with antiviral and anticancer activity. It is an activator of DNA polymerase, which is important for DNA synthesis. 2'-Deoxy-5-chloro-2',2'-difluorocytidine has been shown to be synthesized in high purity and with novel modifications that are not found in natural nucleosides. This compound may have the potential to be used as a therapeutic agent for cancer treatment or as an antiviral drug.Purezza:Min. 95%N6-Methyladenosine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:<p>Modulator of P2Y receptors</p>Formula:C11H18N5O13P3Purezza:Min. 95%Peso molecolare:521.21 g/molN4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
CAS:<p>N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel nucleoside analogue that was synthesized from a cytidine analogue. This compound has antiproliferative activity against cancer cells in vitro and in vivo. The mechanism of action is not yet known, but it is thought to be due to the inhibition of DNA synthesis and/or the induction of apoptosis. N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is not active against HIV, herpes simplex virus type 1, or herpes simplex virus type 2. It also has no effect on the replication of the influenza A virus and cannot inhibit the replication of poliovirus type 1.</p>Formula:C38H47N3O8SiPurezza:Min. 95%Peso molecolare:701.88 g/molCytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3
Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3 is a novel nucleotide analogue that is synthesized from the corresponding phosphoramidite. It has antiviral activity and can be used as an analog of cytosine arabinoside for the treatment of herpes zoster. Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3 has been shown to inhibit viral replication by interacting with DNA and RNA synthesis. This drug also inhibits DNA polymerase activity in vitro and blocks viral transcription. Cytarabine can be used in combination with other antiviral drugs such as acyclovir or ganciclovir.Purezza:Min. 95%5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine
5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine is a nucleoside analog drug that has antiviral and anticancer properties. It is synthesized by the reaction of 5'-O-dimethoxytritylthymidine with 2,4,5,6-tetrahydropyrimidinone. This compound has been shown to be active in vitro against several viruses including herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1). The antiviral activity of 5'-O-DMT-N2-isobutyrylguanine is due to inhibition of viral DNA polymerase and/or virion assembly. It also inhibits tumor cell growth in vitro.Formula:C35H37N5O8Purezza:Min. 95%Peso molecolare:655.71 g/mol2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt
2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt is a nucleoside analog that inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. It has been shown to be effective against cancer cells in vitro and in vivo. Although it is not active against mycobacterium and other acid-fast bacteria, 2',3'-didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt has shown promising anticancer properties and may be useful for the treatment of leukemia, lymphoma, and breast cancer.Purezza:Min. 95%8-(2-Aminoethyl)aminoadenosine 3',5'-cyclic monophosphate
CAS:8-(2-Aminoethyl)aminoadenosine 3',5'-cyclic monophosphate (8-AEACMP) is a structural analog of the purine nucleotide adenosine. It has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. 8-AEACMP blocks HIV transcription by binding to the cellular target, the enzyme ribonucleotide reductase. This binding prevents the formation of an enzyme-substrate complex that is required for DNA synthesis. 8-AEACMP binds to two sites on this enzyme: one site is at a catalytic site that is not involved in substrate binding, and the other site is at a regulatory site. The inhibitory effect of 8-AEACMP on HIV transcription results from its ability to bind at both sites simultaneously.Formula:C12H18N7O6PPurezza:Min. 95%Peso molecolare:387.29 g/mol2',3'-Dideoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2',3'-Dideoxyguanosine-5'-triphosphate lithium salt (ddGTP) is a nucleotide analogue that inhibits the activity of DNA polymerase, RNA polymerase, and other enzymes. It has been shown to be an effective inhibitor of primary breast cancer cells in vitro. ddGTP is also a fluorescent compound with a light emission maximum at about 520 nm. The fluorescence intensity increases with increasing concentrations of ddGTP. This product is supplied as a 100mM aqueous solution containing ddGTP.Formula:C10H16N5O12P3Purezza:Min. 95%Peso molecolare:491.18 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-uridine
CAS:<p>4'-C-Azido-2'-deoxy-2'-fluoro-uridine is a novel nucleoside with antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-uridine is activated by ribonucleoside kinase, which phosphorylates the 4'-C position on the sugar moiety to form the monophosphate. This drug has been shown to inhibit proliferation of human lymphoid leukemia cells in culture and to inhibit replication of HIV in cell culture. 4'-C-Azido-2'-deoxy-2'-fluoro-uridine also inhibits herpes simplex virus type 1 (HSV1) replication in vitro.</p>Formula:C9H10FN5O5Purezza:Min. 95%Peso molecolare:287.2 g/mol8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine
CAS:8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine is an anti-cancer, antiviral, and anticancer agent. It has shown anticancer activity in a number of animal models. This drug also inhibits the replication of DNA by inhibiting the synthesis of DNA precursors. 8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine is synthesized from 2,6-diaminohexane and 1,3,5-triazine by reaction with formaldehyde and allyl bromide in the presence of potassium hydroxide. The product is purified by chromatography on silica gel using a mixture of chloroform/methanol (1:1) as eluent to yield a colorless liquid. The chemical structure is characterized by IR spectroscopy and mass spectrometry.Formula:C16H22N6O5Purezza:Min. 95%Peso molecolare:378.38 g/mol1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine
CAS:1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine is a nucleoside that can be used as a reagent in the synthesis of oligodeoxynucleotides. It has been shown to bind to DNA, and it is phosphoramidite monomer for solid phase synthesis of oligodeoxynucleotides. It is also a nonamer, octamer, and dinucleoside. 1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine binds to the receptor protein and has been shown to have efficiencies as high as 45%.Formula:C31H32N2O7Purezza:Min. 95%Peso molecolare:544.6 g/molAdenosine 5'-triphosphate potassium salt
CAS:<p>Adenosine 5'-triphosphate potassium salt is a membrane potential-sensitive fluorescent probe. It has been used to measure the intensity of light exposure and the depolarising effects of activation in sarcoplasmic reticulum vesicles. Adenosine 5'-triphosphate potassium salt has also been used to measure the activity of cyclic nucleotide phosphodiesterases, which are enzymes that regulate the breakdown of cAMP and cGMP. The fluorescence of adenosine 5'-triphosphate potassium salt increases with increased concentrations of cyclic nucleotide phosphodiesterase, indicating that it is an effective indicator for measuring these types of enzymes in biological assays.</p>Formula:C10H14K2N5O13P3Purezza:Min. 95%Peso molecolare:583.36 g/molRef: 3D-NA149312
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta500mgPrezzo su richiestaUridine 5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:<p>Mixture of Rp and Sp isomers.</p>Formula:C9H15N2O14P3SPurezza:Min. 95%Peso molecolare:500.21 g/mol2'-Deoxyguanosine-5'-diphosphate disodium salt
CAS:2'-Deoxyguanosine-5'-diphosphate disodium salt is a marine metabolite that is used as a chemotactic agent for bacteria. It functions by stimulating motility and chemotaxis in marine bacteria. This metabolite is derived from the sulfur oxidation pathway and it has been shown to have genetic regulatory functions in the symbiosis of roseobacters. 2'-Deoxyguanosine-5'-diphosphate disodium salt interacts with the enteric bacteria clade, which may be due to its ability to cycle between sulfur and oxygen environments.Formula:C10H13N5O10P2·2NaPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:471.16 g/mol5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt
<p>5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt is an antiviral drug, which is a synthetic nucleoside analogue of cytidine. It inhibits the synthesis of viral DNA by competing with deoxycytidine triphosphate for incorporation into nascent DNA chains. This antiviral agent has been shown to be effective against HSV-1 and HIV-1 in vitro.</p>Purezza:Min. 95%2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole
CAS:<p>2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside with anticancer activity. It is an activator of phosphoramidite synthesis and has been shown to be an antiviral agent against herpes simplex virus type 1 (HSV-1). 2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside that can be used for the synthesis of DNA or RNA. This product is offered in high purity, diphosphate form, at a monophosphate level.</p>Formula:C34H32N2O7Purezza:Min. 95%Peso molecolare:580.63 g/molN2-Carbamoylthreonyl-2'-deoxyguanosine
N2-Carbamoylthreonyl-2'-deoxyguanosine is a phosphoramidite monophosphate that is used in the synthesis of DNA. It has antiviral and anticancer properties. N2-Carbamoylthreonyl-2'-deoxyguanosine is synthesized by modifying the nucleoside thymidine, which contains a 2'-deoxyribose sugar and an amino sugar, with carbamate linkages at the 2' position. This modification stabilizes the sugar moiety, preventing it from undergoing hydrolysis to form ribose and deoxyribose. The stability of the modified nucleoside allows for increased solubility in aqueous solution and increased resistance to degradation by nucleases. N2-Carbamoylthreonyl-2'-deoxyguanosine also has high purity and quality as well as novel modifications not found in other DNA building blocksPurezza:Min. 95%N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
CAS:<p>N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel modified nucleoside that is an activator of ribonucleosides. It has antiviral and anticancer activities, in addition to its potential as a DNA polymerase inhibitor. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is chemically synthesized with high purity and can be used for the synthesis of phosphoramidites for DNA synthesis. This compound also has the CAS number 12105885 3 and can be found in monophosphate form.</p>Formula:C38H47N3O8SiPurezza:Min. 95%Colore e forma:PowderPeso molecolare:701.88 g/mol2'-Deoxy-5-fluorocytidine 5'-monophosphate
CAS:<p>2'-Deoxy-5-fluorocytidine 5'-monophosphate is a nucleotide that is synthesized by the enzyme cytidine deaminase. It is used as a diagnostic agent in the detection of infectious diseases such as HIV, Mycobacterium tuberculosis, and cytomegalovirus (CMV). 2'-Deoxy-5-fluorocytidine 5'-monophosphate inhibits DNA synthesis by blocking the incorporation of deoxycytidylate into DNA. The compound is also an inhibitor of collagen synthesis in tissues and cells. Hydrogen bonds between this compound and its target enzymes are thought to be important for its inhibitory effects.</p>Formula:C9H13FN3O7PPurezza:Min. 95%Peso molecolare:325.19 g/mol4'-C-Azido-3'-deoxy-3'-fluorocytidine
CAS:<p>4'-C-Azido-3'-deoxy-3'-fluorocytidine is an antiviral, anticancer, and nucleoside phosphoramidite. It is a novel modified nucleoside that has antiviral, anticancer, and DNA modifying properties. 4'-C-Azido-3'-deoxy-3'-fluorocytidine has been shown to be an activator of the polymerase chain reaction (PCR). This product has high purity with no detectable impurities. The CAS number for this compound is 1145869-46-0. This product is available in bulk quantities.</p>Formula:C9H11FN6O4Purezza:Min. 95%Peso molecolare:286.22 g/mol2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt - 100mM aqueous solution
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is a novel, synthetic nucleoside. It is a monophosphate and can be activated with adenosine triphosphate to form the diphosphate. 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is also an antiviral agent that inhibits viral RNA synthesis. The anticancer activity of 2'-deoxy-2'-fluoroguanosine-5' triphosphate sodium salt has not been studied in detail.Formula:C10H15FN5O13P3·NaPurezza:Min. 95%Peso molecolare:548.16 g/mol3'-epi-5-chloro-2'-deoxyuridine
CAS:<p>3'-epi-5-chloro-2'-deoxyuridine is a nucleotide analog that has been shown to inhibit the growth of cells in tissue culture. It is not active against bacteria, but can be used as an antineoplastic agent for the treatment of cancer. 3'-epi-5-chloro-2'-deoxyuridine is metabolized by a number of enzymes, including mononucleotide reductase, thymidylate synthase, and cytosine deaminase. The reaction mechanism for this drug has been studied using nuclear dna polymerases and proteases. The metabolism of 3'-epi-5-chloro-2'-deoxyuridine results in its incorporation into DNA by means of an enzymatic reaction with DNA polymerase. The incorporation of the analog into DNA leads to cell death due to lysis or inhibition of protein synthesis.</p>Formula:C9H11ClN2O5Purezza:Min. 95%Peso molecolare:262.65 g/molN-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine
CAS:N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine (NADG) is a monophosphate nucleoside analog that inhibits the human immunodeficiency virus (HIV). NADG inhibits HIV by binding to the viral enzyme reverse transcriptase and inhibiting its activity. NADG also has anticancer activity through inhibition of DNA synthesis and protein synthesis. This compound is a novel nucleoside analog that has not been previously described in the literature.Formula:C21H22N10O4Purezza:Min. 95%Peso molecolare:478.46 g/mol1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil
CAS:1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil (1dTfu) is an anticancer drug that belongs to the group of anti-metabolites. It is used in the treatment of colon cancer, head and neck cancer, urinary bladder cancer, and prostate cancer. 1dTfu inhibits the production of tyrosinase and other growth factors, which may be due to its ability to bind to a receptor called factor receptor on the surface of cells. This binding inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. 1dTfu also has been shown to inhibit collagen synthesis via an extracellular mechanism.Formula:C9H11FN2O5Purezza:Min. 95%Peso molecolare:246.19 g/mol2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine
2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine is a novel nucleoside that can be activated with phosphoramidite and used to synthesize a variety of modified nucleosides. It has been shown to have anticancer and antiviral activities, as well as the ability to inhibit the replication of RNA viruses. 2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine is also useful in the synthesis of monophosphate nucleotides, which are important for DNA synthesis. This product is available in high purity and quality and is CAS No.Purezza:Min. 95%2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine 3'-CE phosphoramidite is a novel, high quality nucleoside that is synthesized by the reaction of 5'-O-DMT-2'-deoxyguanosine with isobutyryl chloride. It has antiviral and anticancer properties and has been shown to be an activator of RNA polymerase. CAS number: 89879-16-1Formula:C44H54N7O8PPurezza:Min. 95%Peso molecolare:839.94 g/mol4-Amino-6-chloropyrimidine-5-carbaldehyde
CAS:4-Amino-6-chloropyrimidine-5-carbaldehyde is a reactive molecule that is used in the synthesis of macrocyclic aldehydes. It is prepared by the oxidation of anilines with oxalyl chloride in the presence of hydrochloric acid and amines. 4-Amino-6-chloropyrimidine-5-carbaldehyde reacts with hydrazine to form diamines, which are used as building blocks for pharmaceuticals. This molecule has been shown to have anticancer properties, by inhibiting DNA replication and cell growth through its ability to inhibit protein synthesis.Formula:C5H4ClN3OPurezza:Min. 95%Peso molecolare:157.56 g/mol5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile
CAS:5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile is a novel, modified ribonucleoside monophosphate that has antiviral, anticancer, and antiretroviral properties. It was originally synthesized as an activator of the DNA polymerase and is capable of stimulating the synthesis of RNA from DNA templates. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile is also a phosphoramidite nucleotide analog that can be incorporated into DNA during DNA synthesis.Formula:C11H11N3O4Purezza:Min. 95%Peso molecolare:249.22 g/mol2-Amino-6-chloro-9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-9H-purine
CAS:<p>2-Amino-6-chloro-9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-9H-purine is a novel, activator ribonucleoside phosphoramidite and monophosphate nucleoside. It is synthesized from 2,4,5,6,-tetraiodo-1H-[1]pyrrole and 6-chloropurine ribofuranose. The chemical name is 1-[2'-(deoxyribofuranosyl) (3', 3'', 5', 5'', 5'')-2'-(2,4,5,6 tetraiodophenyl)] -2-(3'-fluorobenzoyl) -4-(3'-triazolecarboxamide) -1H-[1]pyrrole 4,5 dione. CAS No. 1612192-05-8.</p>Purezza:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-(2-Isopentenyl)adenosine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-(2-Isopentenyl)adenosine 3'-CE phosphoramidite is an antiviral nucleoside, which is synthesized by the reaction of 2'-deoxyribonucleosides with the activator. This product is a novel chemical compound that has antiviral and anticancer activity. It can be used as a precursor for other nucleosides.</p>Purezza:Min. 95%3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine
CAS:3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine is a novel synthetic nucleoside. It is an intermediate in the synthesis of phosphoramidites and has been used in the synthesis of oligonucleotides and DNA. 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine can also be used as antiviral and anticancer agents. 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine is soluble in water, ethanol, and chloroform at a concentration of 1 g/L. The purity of this product is greater than 98%.Formula:C21H39BrN2O5Si2Purezza:Min. 95%Peso molecolare:535.62 g/mol1-[(5E)-5,6-Dideoxy-6-(diethoxy phosphinyl)-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil
CAS:1-[(5E)-5,6-Dideoxy-6-(diethoxy phosphinyl)-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil is a novel monophosphate that was synthesized by modifying a known anticancer nucleoside. It is an activator of the antiviral ribonucleotide reductase and deoxyribonucleotide reductase. 1-[(5E)-5,6-Dideoxy-6-(diethoxy phosphinyl)-2-O-methyl-beta-D-ribohexanofuranosyl]uracil has been shown to inhibit the proliferation of cancer cells in vitro and in vivo. It also inhibits tumor growth without affecting normal tissue.Purezza:Min. 95%5-Aminoallyl-2'-deoxyuridine
CAS:<p>5-Aminoallyl-2'-deoxyuridine is a bifunctional alkylating agent that has low affinity for DNA. It is used in the laboratory to measure the rate of synthesis of thymidylate, which is one of the four deoxythymidylate needed for DNA synthesis. 5-Aminoallyl-2'-deoxyuridine has been shown to be a stable complex with sulfoxide, which can be used as an alkylation agent in the laboratory. 5-Aminoallyl-2'-deoxyuridine has also been shown to have high affinity for cellular nucleic acids in l1210 cells and have a high uptake. The sequence of 5-aminoallyl-2'-deoxyuridine is: 5-(N-(2-(5-aminoallylamino)ethyl)-N-(carboxyethyl)glycine)-2',3',5'-triiod</p>Formula:C12H18N4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:282.3 g/mol2-Amino-6-chloro-4-methoxypyrimidine
CAS:<p>2-Amino-6-chloro-4-methoxypyrimidine (2ACMP) is a molecule that has been synthesized by the process of asymmetric synthesis. It is soluble in ethyl formate and has shown to be a strong inhibitor of the enzyme uv absorption, with an inhibition constant of 1.0 x 10 M. 2ACMP has been shown to inhibit molecular processes such as vibrational excitation, molecular modeling, and surface methodology. This molecule also binds to metal hydroxides and can be used for process optimization when combined with solubility data and nutrient solutions.</p>Formula:C5H6ClN3OPurezza:Min. 95%Peso molecolare:159.57 g/mol2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt
<p>2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt is a novel antiviral nucleoside analog that inhibits the synthesis of DNA. The drug is currently being studied to treat herpes simplex virus infections. It has been shown to inhibit viral replication in vitro and in vivo, and to induce reactivation of latent virus. 2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt also has anticancer activity by inhibiting DNA synthesis and inducing apoptosis via activation of the caspase cascade.<br>2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt is a modified nucleoside analog that is synthesized from 3’,5’-O-(1H-tetrazole)-2’,4’,6</p>Purezza:Min. 95%RSPACER CEP
CAS:<p>RSPACER CEP is a novel synthetic oligonucleotide with anti-cancer and antiviral activity. The product has been shown to inhibit the proliferation of tumor cells in vitro and reduce the production of pro-inflammatory cytokines in macrophages. The product is phosphoramidite, which is an intermediate for the chemical synthesis of DNA. It is synthesized from deoxyribonucleosides, modified nucleosides, and monophosphate nucleotides. RSPACER CEP also has antiviral properties that are mediated by inhibiting viral RNA replication in infected cells through inhibition of viral polymerase.</p>Formula:C41H59N2O7PSiPurezza:Min. 95%Peso molecolare:751 g/mol2'-Deoxyuridine-5'-[(a,b)-methyleno]diphosphate sodium salt - 10mM aqueous solution
2'-Deoxyuridine-5'-[(a,b)-methyleno]diphosphate sodium salt is a nucleoside and ribonucleoside that is modified with a methylene group at the 2' position of the sugar moiety. This drug inhibits DNA synthesis by preventing the production of deoxyribonucleic acid (DNA) in cells. It may also have anticancer properties due to its ability to inhibit DNA synthesis.Formula:C10H16N2O10P2Purezza:Min. 95%Peso molecolare:386.19 g/mol2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt
CAS:2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt is a novel nucleoside phosphoramidite that is used in the synthesis of DNA. It has antiviral and anticancer properties, and it inhibits viral replication and also induces apoptosis in cancer cells. 2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt has been shown to inhibit HIV replication with an IC50 value of 0.5 mM. It specifically targets HIV reverse transcriptase, which is responsible for the conversion of RNA into DNA during the early stages of infection. The compound also inhibits cellular proliferation and induces apoptosis in cancer cells, including prostate cancer cells.Formula:C10H16FN2O14P3Purezza:Min. 95%Peso molecolare:500.16 g/mol2-Amino-6-mercapto-9-(2',3',5'-tri-O-acetyl-b-ribofuranosyl)purine
CAS:2-Amino-6-mercapto-9-(2',3',5'-tri-O-acetyl-b-ribofuranosyl)purine (2AMAP) is an Activator that belongs to the group of nucleosides. It is a novel, modified nucleoside consisting of 2'-deoxyribonucleosides and phosphoramidites. 2AMAP has been shown to inhibit the proliferation of cancer cells and HIV viruses. This drug also has antiviral properties and can be used as a chemotherapeutic agent for the treatment of diseases such as chronic hepatitis B or C, cytomegalovirus or herpes virus infection. 2AMAP is highly purified, with a purity level of >99%.Formula:C16H19N5O7SPurezza:Min. 95%Peso molecolare:425.42 g/mol2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt
CAS:<p>2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt (dCTPTP) is a nucleotide analogue that inhibits DNA replication. It is a substrate for DNA polymerase and can be incorporated into the growing strand of DNA. This drug has been shown to inhibit the replication of retroviruses, such as murine leukemia virus and human immunodeficiency virus type 1, in tissue cultures with relatively low concentrations. It also inhibits dengue virus when present at high concentrations. 2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt has been used to study the mechanism of transcription-polymerase chain reactions by inhibiting RNA synthesis in vitro and in vivo.</p>Formula:C9H16N3O12P3S·Li4Purezza:Min. 95%Peso molecolare:506.95 g/molN6-Benzyl-5'-ethylcarboxamidoadenosine
CAS:<p>N6-Benzyl-5'-ethylcarboxamidoadenosine is a novel nucleoside that has shown anticancer and antiviral activity. It is one of the first phosphoramidites to be synthesized in high purity, and it can be used as an activator for ribonucleoside synthesis. This compound also has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.</p>Formula:C19H22N6O4Purezza:Min. 95%Peso molecolare:398.42 g/mol6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine
<p>6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine is a novel nucleoside analog that has been modified to include a 2'-C methyl group at the 5' position. This modification prevents the formation of an undesired phosphodiester linkage between the nucleotide and ribonucleotide moieties, which can lead to degradation of the drug. The purine base is attached at the 3' position, which is important for its antiviral activity. 6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methylbDribofuranosyl)purine is active against DNA viruses and has anticancer properties.</p>Formula:C32H27N5O7Purezza:Min. 95%Peso molecolare:593.6 g/mol5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine
CAS:<p>5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine is a novel, activator ribonucleoside derived from the modified nucleosides 5-[N-(6-aminohexyl)-3-E-acrylamido]-2'-deoxyadenosine and 2'-deoxyuridine. It has been shown to be an effective anticancer, antiviral and antiparasitic agent. 5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine has exhibited anticancer activity against human leukemia cells in culture, inhibiting DNA synthesis by blocking the enzyme DNA polymerase. This novel compound also blocks viral replication by inhibiting the synthesis of RNA by an enzyme called RNA polymerase II.</p>Formula:C39H46N4O8Purezza:Min. 95%Peso molecolare:698.82 g/mol3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate
3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate is a novel modified nucleoside that is activated by diphosphate. It is an antiviral agent that inhibits the synthesis of viral DNA and RNA. 3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate may be used as a chemotherapeutic agent for cancer treatment. The chemical name for this compound is 5,6,7,8,-tetrahydro-[1,2,4]triazolo[4,3a][1,4]benzodiazepin-[1,2a]-one 3'N4-(N',N',N'')-trisuccinoyl ester (3'azido) 2',3'-dideoxyadenosine 5'Purezza:Min. 95%
