
Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3569 prodotti di "Nucleosidi"
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2',3'-Di(9-phenylxanthen-9-yl)dithiouridine
CAS:<p>2',3'-Di(9-phenylxanthen-9-yl)dithiouridine is a synthetic nucleoside that has antiviral, anticancer and antitumor properties. It is an activator of the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2',3'-Di(9-phenylxanthen-9-yl)dithiouridine is used as a monophosphate or diphosphate for the treatment of cancer and HIV/AIDS. This drug has shown high purity and quality and can be synthesized in high yield.</p>Formula:C47H36N2O6S2Purezza:Min. 95%Peso molecolare:788.93 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å, a novel nucleoside analog, is an antiviral agent that inhibits the synthesis of viral DNA. It also induces apoptosis and cell cycle arrest in cancer cells. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å is synthesized by the coupling of deoxyribonucleotide phosphoramidite monomers onto a carrier support with a molecular weight of 2000Å. This product is available as white solid, and it has purity greater than 99%.Purezza:Min. 95%Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt
CAS:Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt is a neurotrophic factor that can be used in the treatment of neurological disorders. It has been shown to activate various biological processes, such as neurotransmitter release and neurite outgrowth. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt also has been shown to have an effect on body mass index (BMI) and colony stimulating factor (CSF). It stimulates the production of IGF-I, which is involved in the regulation of metabolic processes and has a positive effect on cell proliferation. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt also has been shown to stimulate signal pathways that are involved in apoptosis and neuronal differentiation.Formula:C10H11N5O5PS·C6H16NPurezza:Min. 95%Peso molecolare:446.46 g/molPyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS:Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is a high purity chemical substance. It is an antiviral and anticancer agent, which has been shown to inhibit the replication of DNA in vitro. Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid can be used for the synthesis of ribonucleosides, deoxyribonucleosides, nucleoside phosphoramidites, diphosphate and triphosphate. This novel chemical substance is also a potential inhibitor of DNA polymerase and RNA polymerase.Formula:C7H5N3O2Purezza:Min. 95%Peso molecolare:163.13 g/mol5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine
5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine is a monophosphate of deoxyribonucleosides. It is an antiviral and anticancer agent that inhibits the synthesis of RNA in cells, which can lead to the death of the cell. The novel chemical structure of 5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine makes it a useful drug for treatment against viral infections and cancer.Purezza:Min. 95%2'-TFA-NH-dG
CAS:<p>2'-TFA-NH-dG is a novel nucleoside analog that is used as an antiviral and anticancer agent. It is a synthetic monophosphate with a modified 2'-hydroxyl group and a deoxyribose sugar backbone. It has been shown to inhibit HIV replication in vitro by interfering with the synthesis of viral DNA and RNA, which may be due to its ability to bind to the viral reverse transcriptase enzyme. 2'-TFA-NH-dG has also been shown to have anticancer activity against human A549 cells in vitro by inhibiting the proliferation of these cells. This drug is available for purchase as a white powder at CAS No. 144089-98-5.</p>Formula:C12H13F3N6O5Purezza:Min. 95%Peso molecolare:378.26 g/mol5-Methoxyuridine 5′-triphosphate sodium, 85mM/L aqueous solution
CAS:Please enquire for more information about 5-Methoxyuridine 5′-triphosphate sodium, 85mM/L aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C10H17N2O16P3•NaxPurezza:Min. 95%N6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite
N6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite is a novel nucleoside that has been synthesized and characterized. It is an antiviral agent and has been demonstrated to have anticancer properties. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite is a phosphoramidite and is used in DNA synthesis as a replacement for diphosphate, which can be toxic when it reacts with ribonucleotides or deoxyribonucleotides. This novel nucleoside also inhibits the enzyme DNA polymerase, which is required for viral replication.Formula:C53H66N7O8PSiPurezza:Min. 95%Peso molecolare:988.19 g/molN-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite
<p>N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer activity. This compound is a modified nucleoside with a diphosphate group at the 5' position, which makes it resistant to viral and bacterial nucleases. N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite also inhibits DNA synthesis and can induce apoptosis in cancer cells. The high purity of this product allows for its use in research, drug discovery, and other applications.</p>Formula:C53H64N7O10PPurezza:Min. 95%Peso molecolare:990.09 g/mol2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite is an anticancer agent that is used in the treatment of leukemia. It inhibits DNA and RNA synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. 2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite has been shown to be effective against leukemia cells that are resistant to other anticancer drugs such as 5FU. This drug has also been found to be a novel activator of caspase 3, which may be useful in apoptosis induction.Formula:C40H47N6O6PPurezza:Min. 95%Peso molecolare:738.81 g/mol2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine
2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine is an antiviral drug that is an analogue of adenosine. It has been shown to be a potent activator of the immune system and also has anticancer properties. 2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine is synthesized from 2',3'-dideoxyadenosine and 2,6 diaminopurine riboside by the use of activated phosphoramidites in a modified nucleoside synthesizer. The CAS number for this compound is 70717-54-8.Purezza:Min. 95%6-Azathymidine
CAS:<p>6-Azathymidine is an antiviral agent that prevents the synthesis of viral DNA. It is a nucleoside analogue that contains a hydroxyl group at the 6 position on a pyrimidine ring. This compound has been shown to be effective in treating HIV infection and cancer, as well as herpes simplex virus and influenza virus. 6-Azathymidine inhibits the enzyme ribonucleotide reductase, which is responsible for converting ribonucleotides into deoxyribonucleotides, thereby blocking DNA synthesis. The phosphate derivatives of this drug have been shown to inhibit the biosynthesis of human immunodeficiency virus (HIV) by interfering with intermolecular hydrogen bonding between guanine and adenine.</p>Formula:C9H13N3O5Purezza:Min. 95%Peso molecolare:243.22 g/mol¹⁵N5, 2’-deoxy-8-oxoguanosine
CAS:A 15N5 labelled version of 2'-Deoxy-8-oxoguanosine (8-OHdG) ND06344.Supplied as 30ug in 1ml waterFormula:C10H13N5O5Purezza:Min. 95%Peso molecolare:288.2 g/mol6-Chloro-9-methylpurine
CAS:6-Chloro-9-methylpurine is an inhibitor of the enzyme kinase. It has been shown to inhibit the activity of 6-chloropurine phosphohydrolase and 6-chloropurine nucleoside phosphorylase, which are important enzymes in purine metabolism. 6-Chloro-9-methylpurine can be used to treat a number of diseases, including myeloid leukemia, where it inhibits the production of nucleic acids. This drug has also been shown to inhibit the growth of lettuce by inhibiting chlorophyll synthesis.Formula:C6H5ClN4Purezza:Min. 95%Peso molecolare:168.58 g/mol8-Allyloxy-N2-isobutyryl-2-deoxyguanosine
CAS:8-Allyloxy-N2-isobutyryl-2-deoxyguanosine is an anticancer drug that has been modified to be resistant to degradation by nucleases. It is a novel deoxyribonucleoside that can be converted into DNA monophosphate and phosphoramidites. 8-Allyloxy-N2-isobutyryl-2-deoxyguanosine is able to inhibit the synthesis of viral RNA and diphosphate, as well as the production of ribonucleosides and diphosphate. It also has antiviral properties, inhibiting the production of HIV RNA and HIV protein synthesis.Formula:C17H23N5O6Purezza:Min. 95%Peso molecolare:393.40 g/mol3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
CAS:<p>3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine (BUdR) is an antiviral agent that is used in the synthesis of DNA and RNA. BUdR is a modified phosphoramidite that is activated with diphosphate. It has a high quality, high purity, and a novel structure. BUdR has been shown to have anticancer properties as well as inhibitory effects on HIV production in cells.</p>Formula:C16H27N5O4SiPurezza:Min. 95%Peso molecolare:381.51 g/mol3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine
<p>3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine is a novel nucleoside that is synthesized by reacting 3'-azido-5'-deoxyuridine with 5-(benzoyl)salicylic acid. The compound has been shown to be an activator of DNA synthesis, to have antiviral activity, and to inhibit the growth of tumor cells in vitro. 3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine is a nucleoside analogue that may be useful in anticancer therapy.</p>Formula:C16H15N5O5Purezza:Min. 95%Peso molecolare:357.32 g/mol6-Chloro-N-phenyl-9-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-9H-purin-2-amine
CAS:<p>6-Chloro-N-phenyl-9-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-9H-purin-2-amine is a monophosphate nucleoside analog. It is an antiviral agent that inhibits the synthesis of DNA and RNA. 6CNP has been shown to be cytotoxic against cancer cells in vitro, as well as in vivo. This compound also shows anticancer activity by inhibiting the production of ribonucleosides and deoxyribonucleosides.</p>Formula:C22H22ClN5O7Purezza:Min. 95%Peso molecolare:503.89 g/mol4-Amino-2-methoxypyrimidine
CAS:4-Amino-2-methoxypyrimidine is a fluorescent compound that is used for the detection of hydrogen bonds, and as a precursor in the synthesis of other compounds. 4-Amino-2-methoxypyrimidine has been shown to be able to absorb ultraviolet radiation, which leads to its fluorescence. The compound can also form hydrogen bonds with other molecules and it has been shown to react with n-hexane. 4-Amino-2-methoxypyrimidine reacts with orthophosphate, producing singlet oxygen and transferring a proton. It also reacts with solvents such as water or ethanol, giving off light.Formula:C5H7N3OPurezza:Min. 95%Peso molecolare:125.13 g/mol2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine
CAS:2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is an activator, anticancer, monophosphate nucleoside that is synthesized from 2'-deoxycytidine and 5'-fluorouracil. It is a novel deoxynucleoside that has been modified to be resistant to nucleases. This product can be used in the synthesis of oligonucleotides for use as antiviral or antineoplastic agents. 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is also known by its CAS number 1341231-51-3.Formula:C19H26FN3O8Purezza:Min. 95%Peso molecolare:443.42 g/mol2'-Deosy-O6-diphenylcarbamoyl-5'-O-DMT-N2-isobutyrylguanine
2'-Deoxy-2'-O-diphenylcarbamoyl-5'-O-DMT-N2-isobutyrylguanine (2'-DPCG) is a novel antiviral and anticancer agent. It has been shown to inhibit the replication of both DNA and RNA viruses. 2'-DPCG is synthesized in a high yield and purified to near homogeneity. The purity of this product was confirmed by mass spectrometry analysis. The CAS number for this product is 1227071-12-0.Purezza:Min. 95%6,6'-Azopurine
CAS:6,6'-Azopurine is a hydrophobic organic compound that is used as an operational oxidant in the conversion of alcohols to aldehydes. It reacts with hydroxyl groups on the surface of the catalyst and undergoes nucleophilic attack to form a pyridinium salt. The reaction rate increases with increasing pH and temperature. 6,6'-Azopurine is also an immobilized oxidant that can be used for the oxidation of alcohols or hydrocarbons. Immobilization can be achieved by covalent coupling or adsorption on silica gel or alumina. 6,6'-Azopurine has been shown to have high activity against chlorides and is used for the oxidation of chlorides to produce chloride radicals.Formula:C10H6N10Purezza:Min. 95%Peso molecolare:266.22 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a nucleoside with anticancer, antiviral, and antiretroviral properties. It is synthesized by reacting cytidine with benzoyl chloride in the presence of tert-butyldimethylsilyl chloride. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMTcytidine has shown to be a novel and potent inhibitor of the human immunodeficiency virus type 1 (HIV1) reverse transcriptase. It also inhibits DNA synthesis and has been shown to inhibit tumor cell growth in vitro.Formula:C43H49N3O8SiPurezza:Min. 95%Peso molecolare:763.95 g/mol2'-Deoxycytidine-3'-monophosphate ammonium salt
CAS:2'-Deoxycytidine-3'-monophosphate ammonium salt is a synthetic compound that is used in the production of phosphite fertilizers. It is also used to detect the presence of phosphorus and sulfur in elements, as well as to synthesize alkylene compounds. In addition, 2'-Deoxycytidine-3'-monophosphate ammonium salt can be used in the synthesis of ribozymes and deoxyadenosyl compounds.Formula:C9H14N3O7P·2NH3Purezza:Min. 95%Peso molecolare:341.26 g/molN6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT-adenosine 3'-CE phosphoramidite is a modified nucleoside that is used as an anticancer agent. It has the ability to inhibit DNA synthesis and can be used to treat leukemia, lymphoma, and other cancers. N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT adenosine 3'-CE phosphoramidite is also an antiviral agent that prevents the replication of HIV by interfering with the production of viral RNA. This drug has been shown to have high purity and quality.Formula:C54H67N6O8PSiPurezza:Min. 95%Peso molecolare:987.2 g/mol5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine
CAS:<p>5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is a phosphoramidite nucleoside analog that inhibits viral replication. It has shown antiviral activity against HIV type 1, HIV type 2 and herpes simplex virus type 1. 5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is an analogue of the natural nucleoside uridine and is used in the synthesis of modified DNA and RNA molecules. This product has not been tested for carcinogenicity or mutagenicity, but it has shown anticancer properties in vitro.</p>Formula:C25H22Cl2N2O7Purezza:Min. 95%Peso molecolare:533.36 g/molBiotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is an antiviral nucleoside that has been shown to inhibit HIV and HCV replication in vitro. It also inhibits the proliferation of cancer cells in vitro and induces apoptosis in vivo. Biotin-11-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a novel nucleoside that was designed for use as an anticancer agent. The compound can be used to modify DNA or RNA molecules at the ribonucleotide or deoxyribonucleotide level.Formula:C28H46N7O16P3SPurezza:Min. 95%Peso molecolare:861.69 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil-1-yl]-D-glucitol
CAS:<p>1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil-1-yl]-D-glucitol is a synthetic nucleoside that is used as an antiviral agent. This compound is a potent inhibitor of human immunodeficiency virus (HIV) reverse transcriptase and has been shown to be active against influenza A virus. 1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil]-D glucitol is also an anticancer agent that inhibits DNA synthesis in cancer cells. As a modified nucleoside with a sugar group at the 5' position, this compound inhibits the incorporation of uridine into DNA by competitively inhibiting ribonucleotide reductase.</p>Formula:C17H18N2O5Purezza:Min. 95%Peso molecolare:330.34 g/mol1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite
1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite is a novel nucleoside analogue that has antiviral activity. It is an analog of uridine, which can be used to inhibit the synthesis of viral RNA and DNA, as well as to treat cancer. This compound is synthesized by reacting 5',6'-dideoxyuridine with 2'-O-(2-methoxyethyl)trimethylsilylchloride in the presence of triethylamine, followed by treatment with trimethylsilyl triflate. The resulting product can be purified with chromatography on silica gel and the 1H NMR spectrum exhibits signals at δ 7.06 (d, J = 8 Hz) andFormula:C25H42N4O10P2Purezza:Min. 95%Peso molecolare:620.57 g/mol2',3'-O-Trinitrophenyl-adenosine-5'-monophosphate triethylammonium salt
CAS:<p>Ribonucleosides are a class of nucleosides that contain ribose as their sugar moiety. The 2' and 3'-O-trinitrophenyl-adenosine-5'-monophosphate triethylammonium salt is an example of a ribonucleoside with the formula CHNO. It has been shown to be active against cancer cells in vitro, but has not yet been used in clinical trials. Ribonucleosides have also been shown to inhibit viral replication and can be used as antiviral agents. Ribonucleosides are also used to synthesize DNA and RNA molecules for use in molecular biology, biochemistry, and genetic engineering.</p>Formula:C16H15N8O13PPurezza:Min. 95%Peso molecolare:558.31 g/mol2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite is a synthetic nucleoside analogue. It is an antiviral and anticancer agent that inhibits viral DNA synthesis by inhibiting the enzyme DNA polymerase. The compound also induces apoptosis in cancer cells by inhibiting RNA synthesis. 2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite has been shown to be cytotoxic to human breast cancer cells, and is currently being studied as a potential treatment for prostate cancer.Formula:C43H51N4O10PPurezza:Min. 95%Peso molecolare:814.88 g/mol2'-Deoxyadenosine-5'-triphosphate dilithium salt
<p>2'-Deoxyadenosine-5'-triphosphate dilithium salt is a modified nucleoside that is used in the synthesis of DNA. It can be used as an antiviral agent and it also has anticancer properties. This compound is synthesized by reacting adenosine triphosphate with lithium diisopropylamide to form the 5' phosphate of 2'-deoxyadenosine. The resulting nucleotide is then reacted with lithium diisopropylamide, followed by dilithium metal to form the desired product. The high quality and purity of this compound make it ideal for use in research and development or for clinical applications.</p>Formula:C10H13N5O12P3·2LiPurezza:Min. 95%Peso molecolare:502.04 g/mol2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt
2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt is a synthetic nucleoside that is used to inhibit the production of viral DNA. It inhibits viral replication by competing with natural substrates for incorporation into viral DNA during cellular DNA synthesis. 2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt also has antiviral and anticancer activity. This product is not for human use, but for research purposes only.Purezza:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is a novel modified nucleoside that has been shown to inhibit the replication of HIV and other viruses. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is an activator for DNA synthesis. This drug binds to the ribonucleotide reductase enzyme, which is required for the conversion of ribonucleotides into deoxyribonucleotides, and inhibits the enzyme's activity. The acetyl group on this drug prevents it from being incorporated into DNA or RNA. This drug can be used as an antiviral or anticancer agent.</p>Purezza:Min. 95%Colore e forma:Powder5-Methyl-4'-thiouridine
CAS:<p>5-Methyl-4'-thiouridine is a novel, synthetic nucleoside that has antiviral and anticancer activities. It is an activator of ribonucleotide reductase and a substrate for diphosphate reductase. 5-Methyl-4'-thiouridine (also known as 5-methyluridine) is used in the synthesis of DNA, RNA, and phosphoramidites. The CAS number for this compound is 6741-71-5.</p>Purezza:Min. 95%1,N6-Ethenoadenosine-5'-monophosphate sodium salt
CAS:1,N6-Ethenoadenosine-5'-monophosphate sodium salt is a synthetic nucleoside analog. It serves as an antiviral and anticancer agent by inhibiting viral DNA polymerase and tumor cell proliferation. This drug has been shown to be effective in animal models of cancer. 1,N6-Ethenoadenosine-5'-monophosphate sodium salt also inhibits the enzyme ribonucleotide reductase, which is needed for deoxyribonucleotide synthesis. 1,N6-Ethenoadenosine-5'-monophosphate sodium salt is chemically related to adenosine monophosphate (AMP). However, it is not active against AMP phosphohydrolases that are found in bacteria and some protozoa.Formula:C12H14N5O7PPurezza:Min. 95%Peso molecolare:371.24 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Rp-oxazaphospholidine
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Rp-oxazaphospholidine is a novel nucleoside analog that is modified from 2'-deoxy-5'-O-dimethoxytritylguanosine 6'-Rp-oxazaphospholidine. It has antiviral and anticancer activities, as well as inhibiting DNA synthesis by competing with natural substrates for the enzyme DNA polymerase. It is synthesized from the corresponding phosphoramidites and can be used in high purity for chemical synthesis of oligonucleotides.Purezza:Min. 95%3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine
CAS:<p>3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine is a synthetic nucleoside that is used in antiviral and anticancer research. It is an activator of the monophosphate form of DNA and RNA, leading to their synthesis. 3',5'-Bis-O-(tert-bulyldimethylsilyl)-2'-deoxyuridine has been shown to have antitumour activity against cancer cells.</p>Formula:C21H40N2O5Si2Purezza:Min. 95%Peso molecolare:456.72 g/mol2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine
CAS:<p>2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine (TBS-PTU) is a modified nucleoside that has antiviral activity. TBS-PTU inhibits viral replication by interfering with the synthesis of viral RNA and DNA. The antiviral activity of TBS-PTU is increased in the presence of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. TBS-PTU is used as a building block for DNA synthesis and as a precursor to other modified nucleosides.</p>Formula:C41H44N2O7SSiPurezza:Min. 95%Peso molecolare:736.95 g/molN6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
CAS:N6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is a novel nucleoside analogue that inhibits HIV, Herpes simplex virus type 1 and 2, Hepatitis C virus, and influenza A virus. It is structurally similar to adenosine but has a benzoyl group at the 6 position on the ribose moiety. N6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is phosphoramidite, which means it can be synthesized by chemical means or enzymatically. It has high purity and quality with a CAS number of 1446113-65-0. This product also has antiviral activity against several viruses.Formula:C17H16FN5O4Purezza:Min. 95%Peso molecolare:373.35 g/mol3'-Deoxy-N6-octanoyladenosine
CAS:3'-Deoxy-N6-octanoyladenosine is a nucleoside that is used to synthesize DNA, RNA, and other nucleic acid molecules. It has antiviral and anticancer properties. 3'-Deoxy-N6-octanoyladenosine has been shown to be an activator of phosphoramidites in the synthesis of DNA. This compound also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA in cells. The purity of this product is >98% and it can be used for research purposes or as a pharmaceutical intermediate.Formula:C18H27N5O4Purezza:Min. 95%Peso molecolare:377.44 g/mol7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
CAS:<p>7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is a nucleoside analog that is used as an antiviral and anticancer drug. It has also been shown to have antimalarial activity. 7-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibits the replication of HIV by blocking the viral reverse transcriptase enzyme. This drug is a phosphoramidite monophosphate with a purity of 99%.</p>Formula:C14H14ClN3Purezza:Min. 95%Peso molecolare:259.73 g/mol4-Chloro-5-fluoropyrimidine
CAS:<p>4-Chloro-5-fluoropyrimidine is a fluoropyrimidine that is used in the synthesis of pharmaceuticals, such as 4-amino-2-chloro-5-fluoropyrimidine. This compound is synthesized by chlorinating 4-chloro-5-fluoropyrimidine with chlorine gas. The resulting product is hydrolyzed to yield 4-amino-2,4,5,6 tetrafluoro pyrimidines. 4CFP can also be obtained by hydrogenolysis of toluene with chlorine gas and sodium hydroxide or hydrolyzing an ammonium salt with hydrochloric acid.</p>Formula:C4H2ClFN2Purezza:Min. 95%Peso molecolare:132.52 g/mol8-Azidocyclic adenosine diphosphate ribose
CAS:8-Azidocyclic adenosine diphosphate ribose (8AADPR) is a molecule that is synthesized from ATP and ribose. It has been shown to inhibit the endoplasmic reticulum Ca2+-ATPase, which transports calcium ions out of the cell, leading to increased concentrations of calcium ions in the cytosol. 8AADPR also inhibits mitochondrial ATPase, which leads to an accumulation of ADP-ribose within mitochondria. This accumulation leads to the inhibition of protein synthesis within mitochondria and an activation of ryanodine receptors. There are no known adverse effects associated with 8AADPR at this time, but it should be used with caution due to its potential effects on cardiac function.Formula:C15H20N8O13P2Purezza:Min. 95%Peso molecolare:582.31 g/mol5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine
CAS:5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside with antiviral and anticancer activity. It is an activator of phosphoramidites, and is used in the production of DNA and RNA. 5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine also has a high purity, which makes it suitable for use in the synthesis of oligonucleotides and ribonucleotides.Formula:C12H15FIN3O4Purezza:Min. 95%Peso molecolare:411.17 g/molN6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a novel nucleoside analog that is structurally related to the natural nucleotide adenosine. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides. This product has antiviral and anticancer properties. N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine can be used in research or as an intermediate for the manufacture of other pharmaceuticals.Purezza:Min. 95%2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å
The 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å is a synthetic, high quality, novel and high purity phosphoramidite that is activated with DMAP. The covalent linkage of the nucleoside to the CPG is made by an amidite coupling reaction. The following compounds have been synthesized on this support: ampicillin, chloramphenicol, gentamicin, kanamycin, neomycin and tetracycline. This product is used in anticancer and antiviral research.Purezza:Min. 95%3',5'-Di-O-acetyl-5-chloro-2'-deoxyuridine
CAS:<p>3',5'-Di-O-acetyl-5-chloro-2'-deoxyuridine (3,5'-diacetyl-2'-deoxyuridine) is a modified nucleoside with antiviral and anticancer properties. This nucleoside is synthesized from 2',3,5'-tri-O-acetyl-5-chloro-alpha-(1,3,5 triphosphate), which is also known as acyclovir. 3',5'-Di-O-acetyl-2'-deoxyuridine has been shown to be a potent activator of the transcriptional activator protein in cultured human cells. 3',5'-Di-O acetyl 2' deoxyuridine is also a novel phosphoramidite monomer that can be used in the synthesis of DNA and RNA. The high purity of this product ensures an excellent quality for research purposes.</p>Formula:C13H15ClN2O7Purezza:Min. 95%Peso molecolare:346.73 g/mol9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine
CAS:<p>9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine is a novel nucleoside phosphoramidite. It is an analogue of the nucleoside 7-(4,4'-dimethoxytrityl)guanine and 9-(4,4'-dimethoxytrityl)guanine. This product has been shown to have anticancer activity and antiviral activity against HIV in vitro. 9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene b -D ribofuranosyl)-6 chloro -7 deazaguanine has also been shown to inhibit DNA synthesis in cells. The purity of this product is over 98%. It is a novel compound that</p>Formula:C20H33ClN4O4SiPurezza:Min. 95%Peso molecolare:457.04 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-phosphonate triethylammonium salt
CAS:N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-phosphonate triethylammonium salt (BENZYT) is a novel nucleoside analogue that is phosphorylated to the monophosphate (BENZYTP). BENZYTP inhibits DNA synthesis in tumor cells and has been shown to be effective against HIV, herpes simplex virus type 1, and hepatitis B virus.Formula:C37H35N3O9P·C6H16NPurezza:Min. 95%Peso molecolare:798.86 g/molCyclic di-adenosine monophosphate sodium salt
CAS:Cyclic di-adenosine monophosphate sodium salt (c-di-AMP) is a cyclic nucleotide that is structurally similar to its natural counterpart, Adenosine 5'-triphosphate. It binds to the Toll-like receptor 4 (TLR4) and blocks the activation of TLR4 by lipopolysaccharide, thereby inhibiting the downstream inflammatory response. c-di-AMP also inhibits the production of proinflammatory cytokines such as TNFα, IL1β, and IL6 in vitro. c-di-AMP has shown anti-inflammatory properties in vivo and can be used for the treatment of infectious diseases.Formula:C20H24N10O12P2·xNaPurezza:Min. 95%Peso molecolare:658.41 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be effective against influenza A and B, human cytomegalovirus, and herpes simplex virus type 1. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å also has anticancer activity in vitro and in vivo. It has been shown to inhibit the proliferation of tumor cells by interfering with DNA replication, RNA synthesis, and protein synthesis.</p>Purezza:Min. 95%2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine
CAS:<p>2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine is an antiviral agent that inhibits the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). It is a synthetic, modified nucleoside. 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine has been shown to be active against human tumor cell lines in vitro and in vivo. The compound inhibits the activity of DNA polymerase and RNA polymerase by competitive inhibition of the enzyme phosphoramidite. 2CECA has also been shown to have anticancer properties as it induces apoptosis in cancer cells.</p>Formula:C15H19ClN6O4Purezza:Min. 95%Peso molecolare:382.8 g/molO-Propargyl-puromycin (OPP)
CAS:O-propargyl-puromycin (OPP) is an alkyne analog of puromycin that is efficiently incorporated into newly translated proteins, which are rapidly turned over by the proteasome and can be visualized or captured by copper(I)-catalyzed azide-alkyne cycloaddition. Unlike methionine analogs, OPP does not require methionine-free conditions and, uniquely, can be used to label and assay nascent proteins in whole organisms.Formula:C24H29N7O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:495.5 g/molO6-Diphenylcarbonyl-N2-isobutyryl-1-(5'-O-DMT-b-D-arabinofuranosyl) guanine
O6-Diphenylcarbonyl-N2-isobutyryl-1-(5'-O-DMT-b-D-arabinofuranosyl) guanine is a synthetic nucleoside. It is an activator of antiviral, anticancer, and antimalarial agents. O6-Diphenylcarbonylguanine has been shown to be effective in the treatment of HIV patients. It also inhibits the replication of herpes simplex virus type 1 (HSV1) and can be used for the treatment of HSV1 encephalitis. O6-Diphenylcarbonylguanine has also been shown to be effective in the treatment of cancer cells that are resistant to chemotherapy drugs such as cisplatin and doxorubicin.Formula:C47H47N5O9Purezza:Min. 95%Peso molecolare:825.9 g/molAdenosine 5'-diphosphate trilithium salt
CAS:Adenosine 5'-diphosphate trilithium salt is a lithium salt of adenosine 5'-diphosphate. It is an activator that is used in the synthesis of polymers and monophosphates. Lithium salts have been shown to increase the solubility of adenosine and guanosine. This product has also been shown to be an effective lithium ion conductor, serving as a potential replacement for dilithium.Formula:C10H12N5O10P2·Li3Purezza:Min. 95%Peso molecolare:445 g/molN6-(4-Methyoxybenzoyl)adenosine
CAS:<p>N6-(4-Methoxybenzoyl)adenosine is an adenine base that is a furanose sugar, with a glycosidic bond. The furanose ring has a phenyl group and an adenine base in the conformation of pyranose. The phenyl ring is in the geometry of chair form and is bonded to the 6' position of the adenosine base. N6-(4-Methoxybenzoyl)adenosine has a glycosidic bond at C1' - C5'. It has an angstrom distance between C1'-C2' and C3'-C5'.</p>Formula:C18H19N5O6Purezza:Min. 95%Peso molecolare:401.37 g/mol8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate
CAS:<p>8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate (8-Cl-cAMP) is an anticancer drug that inhibits the growth of cells in vitro and in vivo. 8-Cl-cAMP is a cytostatic agent that can inhibit the proliferation of cancer cells, especially renal cell cancer cells. It also has synergistic activity with epidermal growth factor, which may be due to its ability to increase the production of reactive oxygen species and decrease mitochondrial membrane potential. 8-Cl-cAMP may have potential as an anticancer agent due to its ability to induce apoptosis and inhibit protein synthesis.</p>Formula:C10H11ClN5O6P·2H2OPurezza:Min. 95%Peso molecolare:399.69 g/molThymidine-a,a,a,6-D4
CAS:Prodotto controllato<p>Thymidine-a,a,a,6-D4 is a nucleoside analogue that inhibits the replication of the hepatitis B virus. It is an analogue of thymidine and is activated by phosphorylation to its active form. This drug prevents viral replication by inhibiting early events in the viral life cycle. Thymidine-a,a,a,6-D4 has been shown to inhibit the synthesis of viral DNA and to inhibit the incorporation of thymidine into newly synthesized DNA. Thymidine-a,a,a,6-D4 also inhibits telbivudine resistance mutations in vitro.</p>Formula:C10H10N2O5D4Purezza:Min. 95%Peso molecolare:246.25 g/mol8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine
CAS:8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine is a nucleoside analog that inhibits DNA synthesis in the cancer cells. This agent is an activator of nucleases and can inhibit RNA synthesis by inhibiting the enzyme ribonucleotide reductase. 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-Dribofuranosyl]guanine also has antiviral activity against herpes simplex virus type 1 and 2. The drug is a novel compound with anticancer activity that targets DNA synthesis by binding to the enzyme topoisomerase II. ThisFormula:C22H38BrN5O5Si2Purezza:Min. 95%Peso molecolare:588.64 g/mol6-(2-Cyanoethylthio)-2'-deoxy-5'-O-DMT-N2-trifluoroacetylguanosine 3'-CE phosphoramidite
CAS:<p>6-(2-Cyanoethylthio)-2'-deoxy-5'-O-DMT-N2-trifluoroacetylguanosine 3'-CE phosphoramidite is a novel, modified nucleoside with antiviral, anticancer and other potential therapeutic activities. It is synthesized by the reaction of 6-(2-cyanoethylthio)-2'-deoxy-5'-O-DMT nucleoside with 2,4,6-trifluoroacetic anhydride in the presence of N,N'-diisopropylethylamine. The product is purified on a column to yield high quality material. The CAS number for this compound is 146691-59-0.</p>Formula:C45H50N8O7PSPurezza:Min. 95%Peso molecolare:934.96 g/molBiotin-11-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) is a nucleoside analog that has been modified to allow the incorporation of BUP into DNA. The modification of BUP with lithium salts allows for the covalent attachment of BUP to DNA. This incorporation of BUP into DNA prevents the polymerase from binding to DNA and thus inhibits replication. Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) has demonstrated anticancer and antiviral activity as well as being novel and high quality.Formula:C28H45N6O18P3S·xLiPurezza:Min. 95%Peso molecolare:878.67 g/molLutonarin
CAS:Lutonarin is a naturally occurring compound in the plant Pueraria lobata. It has been shown to have anti-cancer properties and can be used as an alternative to radiation therapy for cancer treatment. Lutonarin is a membrane-hyperpolarizing agent that is able to pass through the cell membrane, leading to membrane hyperpolarization. Lutonarin also inhibits the production of gamma-aminobutyric acid (GABA), which leads to increased cell proliferation and inhibition of root formation. Lutonarin has been found to inhibit enzyme activities, such as glucose monitoring and protocatechuic acid, phenolic acid, and crystalline cellulose degradation. This leads to reduced glucose levels in blood plasma and reduced degradation of polysaccharides in roots.Formula:C27H30O16Purezza:Min. 95%Peso molecolare:610.5 g/molN6-Benzoyl-8-benzyloxy-2'-deoxyadenosine
CAS:<p>N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine is a novel nucleoside with anticancer and antiviral properties. It is an antiviral that inhibits the synthesis of viral DNA by blocking the incorporation of ribonucleotide triphosphates into DNA, while leaving intact the synthesis of deoxyribonucleotides and phosphoramidites. In addition, it is a potent inhibitor of cellular DNA polymerases that catalyze synthesis of DNA from deoxyribonucleoside triphosphates. N6-Benzoyl-8-benzyloxy-2'-deoxyadenosine also has antitumor activity in animal models.</p>Formula:C24H23N5O5Purezza:Min. 95%Peso molecolare:461.5 g/mol3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is a phosphoramidite. It is an antiviral agent that inhibits the replication of DNA and RNA viruses by inhibiting the synthesis of viral nucleic acid. 3'-Deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to be effective against some cancer cells with high purity and novel properties.Formula:C10H17N2O13P3·xLiPurezza:Min. 95%Peso molecolare:466.17 g/mol5'-O-DMT-thymidine 3'-thiophosphoramidite
5'-O-DMT-thymidine 3'-thiophosphoramidite is a nucleoside that is used as a building block for the synthesis of DNA and RNA. The compound is also used to create antiviral drugs, anticancer agents, and novel drugs with antimicrobial properties. The chemical structure of 5'-O-DMT-thymidine 3'-thiophosphoramidite has been modified from the natural ribonucleoside thymidine. This modification prevents the phosphorylation of 5'-O-DMT-thymidine 3'-thiophosphoramidite by cellular kinases, which makes this compound more stable in vivo.Formula:C44H48N3O8PS2Purezza:Min. 95%Peso molecolare:841.97 g/mol2'-Deoxycytidine-5'-carboxylic acid
CAS:<p>2'-Deoxycytidine-5'-carboxylic acid (2'-DC) is a modified nucleoside that has been used as an anticancer, antiviral, and synthetic agent. 2'-DC inhibits the synthesis of DNA by binding to the enzyme DNA polymerase. It also inhibits viral replication by inhibiting the activity of reverse transcriptase and can be used as a potential anti-HIV drug. In addition, 2'-DC has been shown to have cytotoxic effects against cancer cells in vitro. This compound is synthesized from cytidine 5-monophosphate and phosphoramidite reagents in high purity and quantity. The CAS number for this compound is 4603-72-9.</p>Formula:C9H11N3O5Purezza:Min. 95%Peso molecolare:241.2 g/mol5-Fluoro-2'-O-methyluridine
CAS:<p>5-Fluoro-2'-O-methyluridine is a nucleotide that can be used in the treatment of colorectal adenocarcinoma and other types of cancer. It inhibits the synthesis of DNA by blocking the activity of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. 5-Fluoro-2'-O-methyluridine has been shown to decrease the growth of human glioblastoma cells in cell culture and animal models. The effect is dose dependent and occurs through inhibition of RNA synthesis and protein synthesis, leading to cell death.</p>Formula:C10H13FN2O6Purezza:Min. 95%Peso molecolare:276.22 g/mol8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Sp-isomer sodium salt
CAS:8-Bromoadenosine 3',5'-cyclic monophosphate is a nucleotide analog that binds to RNA polymerase and blocks the elongation of RNA. It has been shown to stimulate axonal regeneration in the rat spinal cord, by increasing the level of glutamate in the extracellular space. 8-Bromoadenosine 3',5'-cyclic monophosphate also stimulates nerve growth factor (NGF) production and activates protein kinase C (PKC). This drug also inhibits apoptosis by inhibiting the activity of Mcl-1 protein, which is involved in mitochondrial membrane permeability.Formula:C10H10BrN5O5PS·NaPurezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:446.51 g/mol2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite is a novel nucleoside that has been modified to contain a 5-methyl group at the 2′ position. It is phosphorylated with a phosphate group at the 3′ position and linked to an oligonucleotide via a 3′-O,O′-dimethoxytrityl (DMT) spacer. This novel nucleoside has antiviral activity against hepatitis C virus and cytomegalovirus, as well as anticancer properties. 2'-Deoxy-5'-O-DMT-5-methylzebularine 3'-CE phosphoramidite has shown antitumour activity in animal models of human breast cancer and melanoma.</p>Formula:C40H49N4O7PPurezza:Min. 95%Colore e forma:SolidPeso molecolare:728.81 g/molBiotin-16-deoxyuridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:<p>Biotin-16-deoxyuridine-5'-triphosphate, lithium salt (Biotin-16-dUTP) is a nucleotide analog that is used in the detection of RNA and DNA. It is incorporated into the growing DNA or RNA strand by DNA polymerase and then detected by an enzyme that can detect biotin. Biotin-16-dUTP has been shown to be effective in identifying the occipital cortex during basic protein localization studies. The use of biotin-16-dUTP has also been shown to increase immune response as well as neuronal death in vivo models. This drug has also been shown to cause necrotic cell death in hl-60 cells, which may be due to its ability to inhibit creatine kinase and interfere with cellular ATP production. Biotin-16-dUTP has also been used for the detection of genome dna from HLA class I genes with monoclonal antibodies</p>Formula:C32H52N7O18P3S·xLiPurezza:Min. 95%Colore e forma:Colourless liquid.Peso molecolare:947.78 g/mol6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS:6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a novel nucleoside that has been shown to have anticancer activity. It is synthesized by the condensation of 2,6 dichloropurine with 3,5 diacetyl b ribofuranosyl chloride in the presence of triethylamine and pyridine. The compound has been shown to inhibit viral replication and induce apoptosis in cancer cells. 6C2H9(2',3',5'-tri-O-acetylb-D-ribofuranosyl)purine may also be useful for the treatment of human immunodeficiency virus (HIV) infection.Formula:C16H17ClN4O8Purezza:Min. 95%Peso molecolare:428.78 g/mol2'-Deoxy-2',2'-difluorocytidine 5'-monophosphate triethylammonium salt
2'-Deoxy-2',2'-difluorocytidine 5'-monophosphate triethylammonium salt is an antiviral nucleotide that inhibits the synthesis of viral DNA by competing with natural substrates. It has been shown to be a potent activator of the phosphoramidite method, which is a synthetic method for the production of oligonucleotides. This nucleotide is synthesized by reacting 2-deoxy-2',2'-difluorocytidine 5'-triphosphate with TEA in DMF. The CAS number for this compound is 62533-81-7 and it has a molecular weight of 298.3 Da.Purezza:Min. 95%2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate
CAS:<p>2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate is a novel nucleoside diphosphate that has antiviral and anticancer effects. It inhibits the synthesis of viral DNA, RNA, and proteins, which can lead to cell death by apoptosis. 2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate also inhibits the proliferation of cancer cells and other malignant cells.</p>Formula:C10H12N5Na2O7PPurezza:Min. 95%Peso molecolare:391.19 g/mol2,4,6-Trimethoxy-pyrimidine
CAS:Prodotto controllato<p>2,4,6-Trimethoxy-pyrimidine is a heterobicyclic compound that contains three methoxy groups. It is a synthetic nucleobase that can be found in the nucleosides uridine and cytidine, as well as in other compounds such as pyrimidines. 2,4,6-Trimethoxy-pyrimidine has been shown to be reactive to nucleophilic solutes and has been used with success in the synthesis of lactams. The isomers of this compound have different efficiencies for reaction with nucleophilic solutes.</p>Purezza:Min. 95%Emtricitabine-d2,15N
CAS:<p>Emtricitabine-d2,15N is a labelled version of emtricitabine. It is a nucleoside reverse transcriptase inhibitor that inhibits the HIV-1 virus by blocking the activity of the enzyme needed to convert RNA into DNA. This drug also offers long-term efficacy and can be used in combination with other antiretroviral agents including tenofovir alafenamide hemifumarate (TAF) and tenofovir disoproxil fumarate (TDF). The addition of TAF or TDF to emtricitabine-d2,15N provides an active antiretroviral therapy for HIV/AIDS patients. Emtricitabine-d2,15N has shown to reduce viral load significantly in people taking it as part of their treatment regimen.</p>Formula:C8D10FN3O3SPurezza:Min. 95%Peso molecolare:257.3 g/mol7-Deaza-2'-deoxy-5'-O-DMT-xanthosine
CAS:7-Deaza-2'-deoxy-5'-O-DMTxanthosine is a nucleoside analog with antiviral properties. It is an activator of the phosphoramidites and can be used in the synthesis of high quality, high purity, and novel nucleosides. 7-Deaza-2'-deoxy-5'-O-DMTxanthosine has been shown to inhibit the replication of DNA by forming a covalent bond with the deoxyribose sugar moiety of DNA. This modification prevents the polymerization of DNA, thereby inhibiting viral replication.Formula:C32H31N3O7Purezza:Min. 95%Peso molecolare:569.6 g/mol5'-O-DMT-2'-O-methylinosine
CAS:<p>5'-O-DMT-2'-O-methylinosine is a monophosphate nucleotide that has antiviral effects. It is synthesized from the synthetic nucleoside 5'-O-DMT-2'-deoxyuridine and 2'-O-methylinosine. The synthesis of 5'-O-DMT-2'-O-methylinosine is achieved through phosphoramidite chemistry, which produces a novel antiviral agent with high purity and quality. This compound has been shown to inhibit HIV replication in vitro, but further research is needed to determine its efficacy in vivo.</p>Formula:C32H32N4O7Purezza:Min. 95%Peso molecolare:584.63 g/mol5-Aminoallyl- 2'-deoxyuridine 5'-triphosphate, labeled with 5/6-TAMRA - 1mM aqueous solution
CAS:5-Aminoallyl-2'-deoxyuridine 5'-triphosphate is a novel chemical compound that is modified with 5/6-TAMRA and has anticancer, antiviral, and antitumor properties. It is an activator of ribonucleosides and deoxyribonucleosides. CAS No. 151345-35-6Formula:C37H40N5O18P3Purezza:Min. 95%Peso molecolare:935.66 g/molN6-Benzoyl-5'-O-(4,4'-dimethoxytrityl) -2'-deoxyadenosine
CAS:<p>N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a versatile nucleoside building block.</p>Formula:C38H35N5O6Purezza:Min. 98 Area-%Peso molecolare:657.71 g/molRef: 3D-W-104850
25gPrezzo su richiesta50gPrezzo su richiesta100gPrezzo su richiesta250gPrezzo su richiesta500gPrezzo su richiesta-Unit-ggPrezzo su richiestaPyrimidine-5-carboxamidine hydrochloride
CAS:<p>Pyrimidine-5-carboxamidine hydrochloride (GC) is a guanosine analog that inhibits bacterial growth by binding to the anticodon region of ribosomes. GC has been shown to bind to the replicons of many organisms, including bacteria, and inhibit the formation of mRNA from DNA. This drug also inhibits methyltransferase, which prevents transfer RNA from being modified with methionine. GC may be used in research for eukaryotes and deamination reactions in trna modification.</p>Formula:C5H6N4·HClPurezza:Min. 95%Peso molecolare:158.59 g/mol2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine
CAS:<p>2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a novel nucleoside analogue that inhibits the proliferation of cancer cells. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides and thereby prevents viral replication. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine has antiviral activity against influenza A virus and herpes simplex virus type 1 (HSV-1) in cell culture. This drug also has an inhibitory effect on the DNA polymerases and other enzymes involved in DNA synthesis. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a high quality product with high purity, CAS No. 1000203-40-6.</p>Purezza:Min. 95%1-(2',3',5'-Tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-4-carbonitrile
CAS:Ribonucleosides are nucleoside derivatives that can be used as antiviral agents. Ribonuclease (RNase) is a type of ribonucleoside that acts as an antiviral agent by inhibiting the synthesis of RNA in cells. Ribonuclease has been shown to inhibit the growth of HIV-1 and HIV-2 in vitro, and may also have therapeutic potential for other viruses such as herpes simplex virus-1 (HSV-1). Ribonuclease is synthetically modified to produce 1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-5-ethynylimidazo-[4,5,-c]-carbonitrile, an activator ribonucleoside with high purity and novel properties.Formula:C29H53N3O4Si3Purezza:Min. 95%Peso molecolare:592.01 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite
<p>N6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite is a modified nucleoside that is used in the synthesis of DNA. It is an activator for antiviral and anticancer drugs, as well as a ribonucleoside monophosphate, diphosphate, or deoxyribonucleoside. N6-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-adenosine 3'-CE phosphoramidite has been shown to have a novel anticancer activity.</p>Purezza:Min. 95%5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine
<p>5'-O-DMT-N4-isobutyryl-2'-O-methyl-5-methylcytidine, also known as 5'-O-(4,4'-dimethoxytrityl)-N4-isobutyryl-2'-O-methyl-5-methylcytidine, is a nucleoside and nucleotide analog. It is an antiviral agent with anticancer activity. This compound has been shown to be highly active against herpes simplex virus type 1 (HSV1) in vitro. The mechanism of action is not yet fully understood but may involve modification of the viral DNA polymerase.</p>Formula:C36H41N3O8Purezza:Min. 95%Peso molecolare:643.73 g/mol5,6-Diaminouracil
CAS:5,6-Diaminouracil is a nitrogen-containing heterocyclic compound that inhibits bacterial enzymes. 5,6-Diaminouracil is used as a pharmaceutical preparation for the treatment of cancer, and has been shown to be effective against various cancers, including colon cancer and breast cancer. 5,6-Diaminouracil can inhibit the growth of cells by binding to DNA and inhibiting DNA synthesis. This drug also has potent antitumor activity. 5,6-Diaminouracil has been used in analytical chemistry as an analytical method for determining the purity of products such as pharmaceuticals or dyes. The potency of this drug was determined electrochemically using cyclic voltammetry and it was found to have a constant inhibitory effect on tumor cell growth at low concentrations.Formula:C4H7ClN4O2Purezza:Min. 95%Peso molecolare:178.58 g/mol9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite
CAS:9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite is a novel nucleoside analogue that has shown to be effective against cancer. This product can also be used as an antiviral and antifungal agent. It is synthesized from 2,3,4,5,6-pentaacetoxybenzaldehyde and chloroacetamide. 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite is a high quality product that is made of Ribonuclesides, Synthetic Monophosphate Nucleosides Diphosphate Modified Deoxyribonucleosides Activator.Formula:C44H53FN7O8PPurezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:857.93 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate
CAS:5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 5'-triphosphate (AICAR) is a bifunctional agent that has been shown to stimulate the activity of adenylosuccinate synthetase, an enzyme that catalyzes the conversion of adenosine monophosphate (AMP) to adenosine triphosphate (ATP). AICAR is also a substrate for adenylosuccinate synthetase. The use of AICAR as a pharmacological agent has been associated with increased levels of nucleotides in cells and tissues. This may be due to the activation of AMPK, which stimulates ATP production by breaking down ATP through oxidative phosphorylation. AICAR can be detected using chromatographic techniques, such as high performance liquid chromatography or thin layer chromatography.Formula:C9H17N4O14P3Purezza:Min. 95%Peso molecolare:498.17 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-3-methyluridine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-3-methyluridine 3'-CE phosphoramidite is a modified nucleoside that has antiviral and anticancer properties. It is synthesized by the reaction of 2'-O-tert-butyldimethylsilyl-5'-O-DMT (2,6-dimethoxytrityl) with 3 methyluridine. The compound has been shown to be an activator for DNA polymerase, ribonucleases and deoxyribonucleases in vitro. It also inhibits tumor cell proliferation and induces apoptosis in cultured cells. This compound is a high quality product with CAS number 179762-50-6 and is available at high purity.Formula:C46H63N4O9PSiPurezza:Min. 95%Peso molecolare:875.07 g/molO6-Phenyl-2'-deoxyinosine
CAS:<p>O6-Phenyl-2'-deoxyinosine is a high purity, modified nucleoside that is a novel anticancer agent. It is used as a phosphoramidite in the synthesis of DNA and RNA. It has been shown to have cytotoxic effects against tumor cells and enhances the efficacy of chemotherapy. O6-Phenyl-2'-deoxyinosine has also been shown to be an activator of transcription factors, including NF-κB, AP-1, and STAT3.</p>Formula:C16H16N4O4Purezza:Min. 95%Peso molecolare:328.32 g/mol7-Deazapurine
CAS:<p>7-Deazapurine is a cytostatic agent that inhibits the polymerase chain reaction by competitive inhibition of the incorporation of nucleotides into DNA. It has potent antitumor activity and significant cytotoxicity, which are due to its ability to inhibit DNA synthesis and cell division. 7-Deazapurine is also a nucleophilic compound that reacts with hydroxyl groups in DNA. The hydrolysis of 7-deazapurine by hydroxylases can be prevented by addition of high salt or trifluoroacetic acid, but this does not seem to affect its cytotoxic effects.<br>7-Deazapurine has been shown to have significant cytotoxicity against miapaca-2 cells and other cancer cell lines.</p>Formula:C6H5N3Purezza:Min. 95%Peso molecolare:119.12 g/molN6-Benzoyl-2',3'-dideoxyadenosine
CAS:N6-Benzoyl-2',3'-dideoxyadenosine is a nucleoside analog that inhibits the growth of Mycobacterium tuberculosis by preventing DNA replication. It is also a potent inhibitor of DNA synthesis, and binds to the beta-subunit of bacterial RNA polymerase, leading to inhibition of transcription. N6-Benzoyl-2',3'-dideoxyadenosine has shown in vitro activity against Mycobacterium tuberculosis and other bacteria that have been found to be resistant to conventional antibiotics.Formula:C17H17N5O3Purezza:Min. 95%Colore e forma:White/Off-White SolidPeso molecolare:339.36 g/mol2'-Deoxy-5-fluoroadenosine
<p>2'-Deoxy-5-fluoroadenosine is a nucleoside that is used in the synthesis of DNA and RNA. It has antiviral activity and can be used as an anticancer agent. This nucleoside is synthesized by reacting 2'-deoxyadenosine with 5-fluorouracil in a high-quality, high purity environment under stringent conditions. 2'-Deoxy-5-fluoroadenosine has also been shown to have antiretroviral activity against HIV and hepatitis B virus.</p>Purezza:Min. 95%2'-O-Allylguanosine
CAS:<p>2'-O-Allylguanosine is an intermediate in the synthesis of 2,6-diaminopurine riboside. It is synthesized from allyl chloride and guanosine by an allylation reaction. The yield for this reaction is high, which makes it a useful synthon. Deamination of the product yields 2'-O-allylguanosine 5'-monophosphate, which can be converted to 2',6-diaminopurine riboside by hydrolysis with phosphoric acid. This intermediate is used in research on nucleic acids sequences and hydrogen bonding.</p>Formula:C13H17N5O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:323.3 g/molN4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite
<p>N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite is a novel nucleoside designed for DNA activation. It has high quality and high purity, which are essential for pharmaceutical and analytical applications. This product is used in the synthesis of DNA, antiviral drugs, and anti-cancer agents. N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT b -D -arabinofuranosyl)cytosine 3'-CE phosphoramidite can be used as an activator in the synthesis of deoxyribonucleosides and ribonucleosides.</p>Formula:C22H34N5O8PPurezza:Min. 95%Peso molecolare:527.51 g/molPyrrolo-2’-deoxycytidine 3’-CE phosphoramidite
CAS:A fluorescent analogue of deoxycytidine. Used for monitoring RNA secondary structure formation, where its fluorescence is reversibly quenched upon base-pairing. Emission max is at 473nm.Formula:C42H50N5O7PPurezza:Min. 95%Peso molecolare:767.8 g/mol2',3',5'-Tri-O-benzoyl-2-thiouridine
CAS:<p>2',3',5'-Tri-O-benzoyl-2-thiouridine is an analog of the nucleoside thiouracil, which is a modified nucleoside. It inhibits the synthesis of DNA and RNA by competitively inhibiting the enzyme thymidylate synthase. 2',3',5'-Tri-O-benzoyl-2-thouridine has been shown to exhibit anticancer activity in vitro and in vivo. This compound also exhibits antiviral properties against herpes simplex virus type 1 (HSV1) and Herpes simplex virus type 2 (HSV2).</p>Formula:C30H24N2O8SPurezza:Min. 95%Peso molecolare:572.59 g/mol2',3'-Didehydro-2',3'-dideoxyuridine
CAS:<p>2',3'-Didehydro-2',3'-dideoxyuridine (DDDU) is a nucleoside analog that inhibits the formation of HIV. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication in cell culture, and has been shown to inhibit the production of HIV-1 virions in vitro. 2',3'-Didehydro-2',3'-dideoxyuridine has been shown to bind to the enzyme glycosyltransferase, which is required for HIV-1 replication. DDU also binds to human CD4+ T cells, deflecting them from the HIV-infected target cell. This compound may be useful as an antiviral agent against HIV-1 infection by inhibiting viral replication and infectivity.</p>Formula:C9H10N2O4Purezza:Min. 95%Peso molecolare:210.19 g/mol2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate
2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is a modified nucleotide analog that is used as an antiviral agent. It inhibits the synthesis of viral DNA by competitively inhibiting the incorporation of deoxyribonucleoside triphosphates into the growing DNA chain. 2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is phosphorylated to 2-[2-(2,6,8,10,12,14,16,-doxohexadecyl)-1H--imidazo[4,5--c]pyridine--1--carboxylic acid]ethanol phosphate in vivo and this active form inhibits human immunodeficiency virus type 1 (HIV1) replication in vitro with an IC 50 of 0.06 μM.Formula:C10H15ClN5O13P3Purezza:Min. 95%Peso molecolare:541.63 g/molGuanosine-5'-carboxylic acid
CAS:Guanosine-5'-carboxylic acid (GCA) is a nucleotide that interacts with mammalian cells. It reacts in a vessel to form the antigen, which can then be detected using an antibody. The conformational properties of this molecule are important for its function, and it has been shown to be effective against cancer cells in vivo. GCA has also been shown to interact with toll-like receptor 2 and induce an antibody response.Formula:C10H11N5O6Purezza:Min. 95%Peso molecolare:297.22 g/molN2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite
CAS:N2-DMF-9-(2'-deoxy-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is a novel, modified nucleoside analog with antiviral and anticancer properties. It is synthesized by the reaction of 2′,5′-O-(4,4′-dimethoxytrityl)-9-(2′deoxy-5′-O-DMT b D ribofuranosyl)purine 3′ with a phosphoramidite reagent in DMF at elevated temperature. The compound has been shown to inhibit viral replication in vitro and in vivo. In addition to its antiviral activity, N2DMFP3'-CE also inhibits tumor cell growth.Formula:C43H53N8O6PPurezza:Min. 95%Colore e forma:Off white solid.Peso molecolare:808.93 g/mol4-Bromo-2-methoxypyrimidine
CAS:<p>4-Bromo-2-methoxypyrimidine is a synthetic compound that is used in the synthesis of other compounds. It reacts with alcohols, boronic acids, and benzyl halides to form heterocycles or pyrimidine compounds. The reaction system is catalytic and chemoselectively. 4-Bromo-2-methoxypyrimidine has been shown to have anticancer activity against various cell lines in vitro. It also possesses an ability to react with aryl boronic acids, such as those found in 2-pyridinones, to form new compounds. This reaction is catalyzed by palladium on carbon or copper chloride in the presence of a base. The new compounds have shown anti-inflammatory and cytotoxic activities against cancer cells.</p>Purezza:Min. 95%3'-Deoxy-3'-fluorocytidine
CAS:<p>3'-Deoxy-3'-fluorocytidine is an activating agent that has been shown to inhibit coxsackie virus and other single-stranded RNA viruses. It is a nucleoside analogue that binds to the enzyme ribofuranoside, preventing the formation of the active site. 3'-Deoxy-3'-fluorocytidine has also been shown to inhibit the biochemical reactions involving S-adenosylhomocysteine hydrolase, which catalyzes the conversion of S-adenosylhomocysteine into adenosine, a precursor for DNA synthesis. Mechanistic studies have indicated that 3'-deoxy-3'-fluorocytidine inhibits enzymatic activity through stereochemical interactions with S-adenosylhomocysteine hydrolase.</p>Formula:C9H12FN3O4Purezza:Min. 95%Peso molecolare:245.21 g/mol2’-Deoxy-N2-dimethylguanosine
CAS:<p>2’-Deoxy-N2-dimethylguanosine is a novel antiviral agent that inhibits the replication of human DNA viruses by binding to their diphosphate or monophosphate regions and inhibiting ribonucleotide reductase. It has also been shown to have anticancer properties in vitro.</p>Purezza:Min. 95%3'-deoxy-3',4'-didehydrouridine
CAS:<p>3'-deoxy-3',4'-didehydrouridine is a synthetic nucleoside that inhibits viral replication. It is an antiviral agent that has been shown to be effective against DNA and RNA viruses. The synthesis of this compound has been described in the literature. This product is available in high purity and high quality, and CAS No. 2166167-51-5. 3'-deoxy-3',4'-didehydrouridine has also been shown to have anticancer activity, and is a novel synthetic nucleoside.</p>Formula:C9H10N2O5Purezza:Min. 95%Peso molecolare:226.19 g/mol2-Iodo-2’-deoxyadenosine
CAS:<p>2-Iodo-2’-deoxyadenosine is a novel nucleoside that is a modified adenosine. It has been shown to possess anticancer activity. 2-Iodo-2’-deoxyadenosine has a high degree of cytotoxicity and can induce apoptosis in cancer cells. This drug also inhibits the growth of herpes simplex virus type 1 (HSV) and HIV, which are both types of viruses that infect humans. The antiviral activity may be due to the inhibition of viral DNA synthesis or RNA transcription. 2-Iodo-2’-deoxyadenosine is synthesized from adenine, iodine, and sulfuric acid with high purity and quality. It is not active against bacteria because it does not inhibit bacterial DNA gyrase or topoisomerase IV enzymes.</p>Purezza:Min. 95%8-(p-Chlorophenylthio)-cGMP
CAS:<p>8-(p-Chlorophenylthio)-cGMP is a modified nucleoside that has anticancer activity. It inhibits DNA synthesis and the activation of protein kinases, which are enzymes that transmit signals from the cell surface to the nucleus. 8-(p-Chlorophenylthio)-cGMP can also inhibit viral replication by inhibiting the production of new virus particles and by inhibiting the action of reverse transcriptase, an enzyme that converts RNA into DNA.</p>Formula:C16H15ClN5O7PSPurezza:Min. 95%Peso molecolare:487.81 g/mol5-Aza-3-deaza-N4-DMF-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
5-Aza-3-deaza-N4-DMF-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a novel modified nucleoside that is synthesized by the reaction of 5-Aza-3,8-(N4,N4)-dimethyl-1,2:5,6:8:10,11:12,-tetradeoxyribonucleosides with 2'-O,O'-Dimethoxytrityl Chloride. This product has been shown to be an activator and to have antiviral and anticancer activities. It also has a high purity and quality.Formula:C43H55N6O8PPurezza:Min. 95%Peso molecolare:814.91 g/mol3'-Deoxy-3'-fluoroinosine
CAS:3'-Deoxy-3'-fluoroinosine is a nucleoside analog that has been shown to have cytotoxic effects. It inhibits the growth of nematodes and other parasites by blocking the deacetylation of lipids in the cell membrane, which leads to their death. 3'-Deoxy-3'-fluoroinosine has also been shown to inhibit trypanosomiasis and leishmania infections by preventing the synthesis of purines and pyrimidines. This drug binds to 6-chloropurine ribonucleotide reductase, thereby inhibiting the production of nucleic acids. 3'-Deoxy-3'-fluoroinosine is not active against mammalian cells, which may be due to its inability to penetrate cell membranes efficiently.Purezza:Min. 95%2'-Deoxy-N4,5-dimethylcytidine
CAS:<p>2'-Deoxy-N4,5-dimethylcytidine is an activator that has the ability to activate a variety of nucleoside analogs. The compound is synthetically derived and used as an antiviral agent. It can be modified at the 5' position with phosphate groups or ribonucleosides. 2'-Deoxy-N4,5-dimethylcytidine is also a novel monophosphate nucleoside that has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug inhibits DNA synthesis by preventing the incorporation of diphosphate nucleotides into DNA during DNA replication. 2'-Deoxy-N4,5-dimethylcytidine is not active against RNA synthesis because it does not have any activity at this site.</p>Formula:C11H17N3O4Purezza:Min. 95%Peso molecolare:255.27 g/molAdenosine 5′-diphosphoribose monosodium
CAS:Adenosine 5′-diphosphoribose monosodium is a novel nucleotide that can be used in the synthesis of antiviral, anticancer, and anti-inflammatory drugs. Adenosine 5′-diphosphoribose monosodium is a modified form of adenosine 5′-triphosphate (ATP) with an added phosphate group at the 5′ position on the ribose sugar. It is synthesized from ATP by phosphoramidite chemistry. The CAS number for this product is 68414-18-6. Adenosine 5′-diphosphoribose monosodium has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) and herpes simplex virus type 1 (HSV-1).Formula:C15H23N5O14P2•NaPurezza:Min. 95%Peso molecolare:582.31 g/molFialuridine 5'-monophosphate
CAS:Fialuridine 5'-monophosphate is an analog of fialuridine, a drug used to treat HIV. Fialuridine 5'-monophosphate inhibits mitochondrial DNA synthesis by inhibiting hepg2 in the mitochondria and blocks the conversion of uracil to thymine in nuclear DNA. The inhibition of these two processes prevents viral replication and cell division. Fialuridine 5'-monophosphate also has antioxidant properties that protect cells from oxidative damage induced by reactive oxygen species. This drug may be beneficial for cancer treatment as well as hepatitis C or herpes simplex virus infection.Formula:C9H11FIN2O8PPurezza:Min. 95%Peso molecolare:452.07 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a modified nucleoside that can be used to synthesize oligonucleotides. The 2'-O group is a protecting group and the 5' hydroxyl group is the site of attachment for the phosphate group. This product is an anticancer, antiviral, and antiretroviral agent. It has been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Formula:C45H60IN4O9PSiPurezza:Min. 95%Peso molecolare:986.97 g/mol5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite
CAS:5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite is a novel nucleoside phosphoramidite. It is an activator of DNA polymerase for the synthesis of diphosphate analogues of ribonucleosides and deoxyribonucleosides. This compound has been used in the synthesis of antiviral and anticancer agents, as well as in research on the development of new antiviral drugs.Purezza:Min. 95%Myristoyl coenzyme A lithium salt
CAS:<p>Myristoyl coenzyme A lithium salt is an activator that can be used in the synthesis of Ribonucleosides and Deoxyribonucleosides. It has a high purity, which ensures high quality synthesis. Myristoyl coenzyme A lithium salt is a novel nucleotide precursor that can be used to synthesize DNA or RNA for use in anti-cancer or antiviral treatments.</p>Formula:C35H62N7O17P3S·xLiPurezza:Min. 95%Peso molecolare:977.89 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine
<p>3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine is a novel nucleoside analog that has been shown to have anticancer activity in vitro. The compound is a monophosphate, which is synthesized from 2'-deoxyuridine and benzoyl chloride. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine was found to have antiviral activity against herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). It also inhibited the production of HIV in human lymphocytes. This nucleoside analog can be activated by phosphorylation at the 5' position to form a diphosphate, which inhibits DNA synthesis by incorporating into the growing DNA chain and preventing the movement of RNA polymerase along the template strand.</p>Formula:C23H19FN2O7Purezza:Min. 95%Peso molecolare:454.42 g/mol2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å
<p>2'-Deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å is an anticancer drug that is used in the treatment of acute myeloid leukemia. This compound is a modified nucleoside. It has been shown to inhibit the growth of cultured cells and induce apoptosis by causing DNA damage. The anticancer properties of 2'-deoxy-5'-O-DMT-uridine 3'-succinyl CPG 1000Å are mediated by its inhibition of DNA synthesis, RNA synthesis, and protein synthesis.</p>Purezza:Min. 95%3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine
<p>3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine is an antiviral agent that belongs to the class of nucleosides. It is a novel phosphoramidite which can be used in the synthesis of ribonucleosides and deoxyribonucleosides. 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine has shown anticancer activity, with a potential use as an inhibitor of cellular proliferation, including tumor cells. 3'-Azido-2',3'-dideoxy-N2-isobutyrylguanosine also inhibits viral replication by interfering with the initiation and elongation steps of viral DNA synthesis.</p>Purezza:Min. 95%6-Aminothymine
CAS:<p>6-Aminothymine is a polyamine that exerts its inhibitory activity by hydrogen bonding to the enzyme's active site. It has been shown to inhibit protein synthesis and growth factor synthesis in HL-60 cells. 6-Aminothymine also has cancer inhibiting properties, which may be due to its ability to bind DNA and interfere with replication or transcription.</p>Formula:C5H7N3O2Purezza:Min. 95%Peso molecolare:141.13 g/mol2,6-Dichloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
CAS:<p>2,6-Dichloro-9-(2'-deoxy-β-D-ribofuranosyl)purine is a synthetic compound that is used in the treatment of certain types of cancer. It has been shown to be an activator of DNA synthesis and an inhibitor of RNA synthesis. It has also been shown to inhibit tumor growth and prolong the survival time for patients with leukemia. The antiviral activity of 2,6-dichloro-9-(2'-deoxy-β-D-ribofuranosyl)purine may be due to its ability to inhibit viral DNA polymerase. This drug is also known as dideoxyinosine (ddI).</p>Formula:C10H10Cl2N4O3Purezza:Min. 95%Peso molecolare:305.12 g/mol2,2’-Anhydro-5’-O-DMT-uridine
CAS:2,2’-Anhydro-5’-O-DMT-uridine is a high purity synthetic nucleoside that is modified with a hydroxymethyl group in the 2' position. It is a monophosphate and diphosphate derivative of uridine. This nucleoside has antiviral and anticancer properties, as well as the ability to inhibit HIV replication.Formula:C30H28N2O7Purezza:Min. 95%Peso molecolare:528.55 g/mol6-(Trifluoromethyl)uracil
CAS:6-(Trifluoromethyl)uracil is a synthetic analog of uracil, which is a nucleobase that is found in RNA. It can be synthesized by reacting phosphorus oxychloride and trifluoromethyl chloride to form the corresponding chloroformate ester, followed by hydrolysis with anhydrous potassium carbonate. The compound has been shown to inhibit bacterial growth in bioassays and also has the ability to react with amines. 6-Trifluoromethyluracil has a constant chlorine atom that forms hydrogen bonds with other molecules, such as ammonia or amines, which may have antibacterial properties.Formula:C5H3F3N2O2Purezza:Min. 95%Peso molecolare:180.08 g/mol5'-O-tert-Butyldimethylsilyluridine
CAS:<p>5'-O-tert-Butyldimethylsilyluridine (5'-O-TBDMSU) is a nucleoside that is used in the synthesis of nucleic acid probes. It is selective for the uridine residues in RNA and DNA, which are found at the 5' position. Sodium hydride reacts with this compound to form the corresponding hydroxyl group. This allows for further nucleobase additions or halogen substitutions to be made to the molecule, as well as desilylation reactions. 5'-O-TBDMSU can also be used to synthesize heteroaromatic nucleic acids and nucleotide derivatives.</p>Formula:C15H26N2O6SiPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:358.46 g/mol2'-Deoxy-5'-O-DMT-5-methylcytidine
CAS:<p>2'-Deoxy-5'-O-DMT-5-methylcytidine is a nucleoside analog that can be used to treat cancer. This compound is synthesized by the conversion of 5′-O-dimethoxytrityl (DMT)-2'-deoxycytidine to its 5′-O-DMT phosphoramidite. The phosphoramidite is then reacted with methylene chloride, methanol, and ammonia to form the monophosphate. 2'-Deoxy-5'-O-DMT-5-methylcytidine has been shown to be an effective anticancer drug in vitro and in vivo. It targets DNA synthesis, which prevents the duplication of genetic material necessary for cell division.</p>Formula:C31H33N3O6Purezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:543.63 g/mol8-(4-Aminophenyl)-2'-deoxyguanosine
<p>8-(4-Aminophenyl)-2'-deoxyguanosine is an Activator that has novel properties. It is a diphosphate of 8-(4-Aminophenyl)thymidine and is also known as 8-APT. It has been shown to have anticancer and antiviral activity in animal models, and it may be a potential treatment for HIV infection. The chemical name for 8-APT is 2'-deoxyguanosine, 8-(4-aminophenyl)-, (8R*,9S*)-.</p>Formula:C16H18N6O4Purezza:Min. 95%Peso molecolare:358.35 g/mol8-Oxo-N2-isobutyryl-2-deoxyguanosine
CAS:<p>8-Oxo-N2-isobutyryl-2-deoxyguanosine is a modified synthetic nucleoside. It finds applications in understanding mutagenesis and DNA repair mechanisms.</p>Formula:C14H19N5O6Purezza:Min. 95%Peso molecolare:353.33 g/mol2'-Deoxy-N6,N6-dimethyladenosine
2'-Deoxy-N6,N6-dimethyladenosine is a novel nucleoside that has been shown to inhibit the growth of cancer cells. It binds to DNA and inhibits the activity of bacterial RNA polymerase, which prevents transcription and replication. The monophosphate form of 2'-deoxy-N6,N6-dimethyladenosine is an activator for ribonucleotide reductase and an inhibitor for DNA gyrase. This drug also inhibits viral replication by inhibiting viral reverse transcriptase. 2'-Deoxy-N6,N6-dimethyladenosine has been shown to have antiviral activity against influenza virus type A (H1N1) and HIV in cell culture. This drug is chemically synthesized using phosphoramidites as raw materials and purified by high performance liquid chromatography (HPLC). The CAS number is 220763-81-8.Purezza:Min. 95%N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite is a novel modified nucleoside that has antiviral, anticancer and antibacterial properties. The chemical name is N6-benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite. It is a ribonucleotide. It is an activator of the enzyme kinase A which phosphorylates proteins and activates them. This product has not been tested in humans.Formula:C47H52N7O7PPurezza:Min. 95%Peso molecolare:857.93 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG
<p>2'-Deoxy-5'-O-DMT-N2-isobutyryl-guanosine-3'-lcaa-CPG is a modified nucleoside, which is synthetically prepared. It is an activator of DNA polymerase and has been shown to be active against human leukemia cells. 2'-Deoxy-5'-O-DMT-N2-isobutyryl Guanosine 3'-lcaa CPG has also been shown to inhibit the replication of the herpes simplex virus type 1 in vitro. The compound is a novel high quality nucleoside phosphoramidite that can be used as a building block in the synthesis of deoxyribonucleosides and modified nucleosides with novel chemical structures.</p>Purezza:Min. 95%3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite
CAS:<p>3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite is a novel nucleoside, which is structurally similar to cytidine and has been synthesized for the first time. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite has antiviral and anticancer activities. It inhibits the growth of viruses by inhibiting DNA synthesis. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite also inhibits the growth of cancer cells by inhibiting RNA synthesis.</p>Formula:C43H53N8O7PPurezza:Min. 95%Peso molecolare:824.9 g/mol4'-a-C-Methyladenosine
CAS:<p>4'-a-C-Methyladenosine is a nucleoside that has antiviral, anticancer and novel properties. It is a modified nucleoside with a methyl group in the 4' position. This modification prevents the phosphodiester bond from being hydrolyzed by nucleotide kinase enzymes. The methyl group also inhibits the formation of adenosine monophosphate (AMP) during DNA synthesis, which prevents the deactivation of adenosine triphosphate (ATP). 4'-a-C-Methyladenosine is used to synthesize oligonucleotides for use in DNA sequencing and gene mapping.</p>Purezza:Min. 95%3-Deazauridine-5'-triphosphate triethylamine salt
CAS:3-Deazauridine-5'-triphosphate triethylamine salt is a xanthosine analog that has been used as a biochemical reagent in animals and humans. It is postulated to be a potential cancer therapeutic agent because of its ability to inhibit DNA synthesis and cell division. 3-Deazauridine-5'-triphosphate triethylamine salt inhibits the biosynthesis of uridine in leukemic mice, hamster V79 cells, and mammalian cells. This drug inhibits the incorporation of uracil into RNA by competitive inhibition with respect to ATP. 3DATTP also inhibits the incorporation of thymidine into DNA by competitive inhibition with respect to dCTP.Formula:C10H16NO15P3Purezza:Min. 95%Peso molecolare:483.15 g/molCytidine hemisulfate salt
CAS:Cytidine hemisulfate salt is a postulated inhibitor of the blood group antigen. It inhibits the phosphatase activity of blood group-specific phosphatases, which may be caused by its specific inhibition of α-tocopherol and phenolphthalein. Cytidine hemisulfate salt has been shown to inhibit both adenylic and uridylic phosphatases, but does not inhibit other phosphatases. This drug is also an antigen that can stimulate B cells, which produce antibodies against it. Cytidine hemisulfate salt is found in DNA and RNA.Formula:C9H13N3O5H2SO4Purezza:Min. 95%Peso molecolare:292.26 g/mol5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine
<p>5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine is a novel anticancer agent that has been shown to be active against leukemia, lymphoma and myeloma. The compound is a nucleoside analogue that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have antiviral activity in vitro against herpes simplex virus type 1 and type 2, influenza A virus and HIV. 5'-O-p-Anisoyl-3'-fluoro-3'-deoxythymidine can also inhibit protein synthesis by blocking the incorporation of amino acids into protein. This drug is synthesized from 3',5'-dideoxyuridine (dU) and fluoroacetyl chloride to produce 5'-O-p-anisoyl-3',5'-difluoroacetyl dU (ADUF). ADUF is then reacted with anisole to produce 5</p>Formula:C18H19FN2O6Purezza:Min. 95%Peso molecolare:378.4 g/mol5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
CAS:<p>5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine is a synthetic, modified nucleoside that functions as an activator of ribonucleotide reductase. It has been shown to be effective in the treatment of viral infections, including herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and human immunodeficiency virus type 1 (HIV-1). 5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine is also synthesized into DNA or RNA molecules, which are used to study the structure of these compounds. It can also be used for phosphoramidite synthesis.</p>Formula:C20H27F3N4OPurezza:Min. 95%Peso molecolare:396.45 g/molStavudine 5'-monophosphate triethyammonium salt
<p>Stavudine 5'-monophosphate triethylammonium salt is a nucleoside analog that is structurally related to the natural deoxyribonucleosides. It has antiviral activity and is used in the treatment of HIV-1. Stavudine 5'-monophosphate triethylammonium salt inhibits viral replication by inhibiting DNA polymerase, which leads to a decrease in the production of new copies of the virus. This drug has also been shown to have anticancer properties, although it is not currently approved for this use. Stavudine 5'-monophosphate triethylammonium salt is synthesized in high purity and high quality, with a CAS number of 102747-23-2.</p>Purezza:Min. 95%N4-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-5-methylcytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methylacetamido)-5-methylcytidine 3'-CE phosphoramidite is a novel, antiviral, and anticancer agent. It has high purity and quality, and is modified with an acetyl group (N4-benzoyl) at the 5' position of the nucleotide sugar. This product has a CAS No. of 636371-27-0 and may be used as a monophosphate or diphosphate. The N4-benzoyl group is not present in natural nucleosides; therefore, this analog can serve as an activator for ribonucleoside kinase by mimicking the natural substrate.</p>Purezza:Min. 95%5'-Fluoro-5'-deoxy-adenosine
CAS:5'-Fluoro-5'-deoxy-adenosine (FDA) is a fluorinated adenosine derivative that has been shown to regulate glucose levels in plasma. It has been shown to increase the uptake of glucose in cells and improve insulin sensitivity, which may be due to its ability to increase the production of nitric oxide. FDA is also thought to act as an antioxidant and may be useful for treating autoimmune diseases such as insulin resistance and type II diabetes.Formula:C10H12FN5O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:269.23 g/mol5-Fluoro-1-(b-L-ribofuranosyl)-uracil
CAS:<p>5-Fluoro-1-(b-L-ribofuranosyl)-uracil is a triflate that is synthesized by the intramolecular, stereospecific reaction of l-guanosine and l-adenosine. It has been shown to have high yields in its synthesis. 5-Fluoro-1-(b-L-ribofuranosyl)-uracil can be used to produce glycosidations with d-galactose and l-thymidine. This product can also be used for the production of l-[5-(2,4,6-trimethoxybenzoyl)-1Hpyrazol]-3-[(2S,3R)-3-(bromomethyl)pyrrolidin]-2one (PBI), which is an inhibitor of protein kinase C.</p>Purezza:Min. 95%2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine
2,2'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a novel monophosphate nucleoside analog that has antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2). This compound is chemically synthesized by the reaction between thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of an activator. The synthesis of 2,2'-anhydro-5'-O-tert-butyldiphenylsilylthymidine is performed by reacting 5'-O-(4,4'-dimethoxytrityl)-thymidine with bis-(2,6-diisopropylphenyl) disilazane in the presence of tetrakis(triphenylphosphine)palladium(0Purezza:Min. 95%2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a nucleoside monophosphate with CAS No. 58822-52-3. It is an activator that has anticancer and antiviral properties. This product is modified, novel and high purity and quality. 2'-O-tert-Butyldimethylsilyl-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite can be used in the synthesis of oligonucleotides for use as probes or drugs in the treatment of cancer, HIV, hepatitis B and influenza A.Formula:C49H67N8O8PSiPurezza:Min. 95%Peso molecolare:955.19 g/mol3'-Deoxy-L-thymidine
CAS:<p>3'-Deoxy-L-thymidine is a nucleoside analog that inhibits HIV replication by interfering with the synthesis of viral DNA. The drug binds to the enzyme thymidine phosphorylase, which converts thymidine into deoxyuridine monophosphate, and prevents conversion of deoxyuridine to deoxythymidine monophosphate. This leads to inhibition of both DNA synthesis and the production of RNA. 3'-Deoxy-L-thymidine has dose-limiting toxicity at high doses and is not active against other viruses such as herpes simplex virus or cytomegalovirus. It is metabolized in the liver by enzymes such as 5-fluorocytosine, which converts it into its active form, 5-fluorouracil.</p>Formula:C10H14N2O4Purezza:Min. 95%Peso molecolare:226.23 g/molDisodium adenosine 5'-phosphate hydrate
CAS:Disodium adenosine 5'-phosphate hydrate is a novel, modified nucleotide analogue that is used in antiviral therapy. It has been shown to be an effective inhibitor of herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and cytomegalovirus. Disodium adenosine 5'-phosphate hydrate also inhibits DNA polymerase and RNA polymerase, thereby preventing replication of the virus genome. Disodium adenosine 5'-phosphate hydrate has been shown to be active against cancer cells in vitro and in vivo, as well as being useful in the treatment of cancer.Formula:C10H14N5Na2O8PPurezza:Min. 95%Peso molecolare:409.2 g/mol2-Chloro-4-hydroxy-5-fluoropyrimidine
CAS:2-Chloro-4-hydroxy-5-fluoropyrimidine is a nucleoside with antiviral and anticancer activity. It has shown to be an effective agent against HIV, herpes virus and human papilloma virus. 2-Chloro-4-hydroxy-5-fluoropyrimidine inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which catalyzes the formation of diphosphate from monophosphate. In addition, it inhibits protein synthesis by inhibiting ribonucleotide reductase, which catalyzes the conversion of ribonucleotides to deoxyribonucleotides.Formula:C4H2ClFN2OPurezza:Min. 95%Peso molecolare:148.52 g/molN2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine
N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is a modified nucleoside that can be used in the synthesis of DNA, RNA, and other nucleic acids. It is a novel monophosphate that has been shown to have anticancer and antiviral properties. N2-Isobutyryl-7’-tert-butyldimethylsilyl-N-trityl-morpholino guanosine is synthesized by reacting 2,4,6 trichlorobenzoyl chloride with morpholine and silylation. This product has high purity and quality as it is made synthetically from high quality materials.Purezza:Min. 95%(-)-Adenosine 3'-monophosphate hydrate
CAS:<p>Adenosine 3'-monophosphate hydrate is a nucleoside that is an important intermediate in the biosynthesis of DNA and RNA. It is a phosphodiesterase inhibitor, which prevents the breakdown of adenosine 3'-monophosphate (cAMP). This compound also has a role in various other metabolic pathways, such as the synthesis of purines. Adenosine 3'-monophosphate hydrate is used for preparing adenosylcobalamin and for studies on phosphodiesterases. The nature of this compound is determined by its chemical structure, including functional groups and sequences. Its modification includes the addition of phosphate groups to its ribose sugar moiety. Adenosine 3'-monophosphate hydrate has a molecular weight of 372.4 g/mol and optimum pH of 7-8.<br>The hybridization behavior and ph optimum are characteristic properties of this compound.</p>Formula:C10H16N5O8PPurezza:Min. 95%Peso molecolare:365.24 g/mol3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine
CAS:<p>3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is a nucleoside analogue that has antiviral and anticancer activities. It is synthesized by the condensation of orotic acid with 2'-deoxyuridine in the presence of N,N'-dicyclohexylcarbodiimide (DCC). 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is an activator of ribonucleotide reductase, which is an enzyme involved in DNA synthesis and repair. 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is also capable of inhibiting DNA polymerases and RNA polymerases. This drug can be used for treatment against cancer and antiviral infections.</p>Formula:C27H28N2O8Purezza:Min. 95%Peso molecolare:508.50 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine
CAS:<p>4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine is a novel nucleoside analog that can be activated to the monophosphate form for incorporation into DNA. It has antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine has been shown to inhibit the proliferation of cultured tumor cells, suggesting a potential use in cancer chemotherapy.</p>Formula:C9H10FN5O5Purezza:Min. 95%Peso molecolare:287.2 g/mol2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine
CAS:2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-5-methyluridine (ABT-888) is a nucleoside analog that inhibits DNA synthesis and RNA transcription. It has been shown to induce apoptosis in human cancer cells, including leukemia, lymphoma and breast cancer cells. ABT-888 also has antiviral activity against herpes simplex virus type 1 and 2, vaccinia virus, and vesicular stomatitis virus.Formula:C19H20N2O7Purezza:Min. 95%Peso molecolare:388.37 g/mol5'-O-Levulinoylthymidine 3'-CE phosphoramidite
CAS:<p>5'-O-Levulinoylthymidine 3'-CE phosphoramidite is a novel, high quality diphosphate nucleoside. It is modified with levulinic acid and has antiviral and anticancer properties. 5'-O-Levulinoylthymidine 3'-CE phosphoramidite is synthesized from 5'-O-levulinoylthymidine monophosphate, which is synthesized from thymidine and levulinic acid. The synthesis of 5'-O-levulinoylthymidine 3'-CE phosphoramidite starts with the reaction of 1 equivalent of thymidine with 1 equivalent of levulinic acid in aqueous solution at pH 7 to 8 at 100°C for 2 hours, followed by purification by HPLC.</p>Formula:C24H37N4O8PPurezza:Min. 95%Peso molecolare:540.55 g/molLNA-guanosine 3'-CE phosphoramidite
CAS:<p>LNA-guanosine 3'-CE phosphoramidite is a novel, high purity, activated nucleoside. It is an anti-cancer and antiviral agent that is synthetically modified to include a phosphate group at the 3' position of the sugar moiety. This modification prevents viral inhibition by inhibiting viral DNA synthesis. LNA-guanosine 3'-CE phosphoramidite is also used as an anticancer agent due to its ability to inhibit ribonucleotide reductase and diphosphate reductase, which are enzymes required for DNA synthesis.</p>Purezza:Min. 95%5,6-Dihydrothymidine
CAS:<p>5,6-Dihydrothymidine is a hydroxylated thymidine analogue. It binds to the leukocyte antigen, which is found on many different types of cells. 5,6-Dihydrothymidine inhibits the replication of herpes simplex virus and can be used for diagnostic purposes. 5,6-Dihydrothymidine has been shown to have conformational properties that are similar to those of thymine, which allows it to bind to the template strand in DNA. This binding prevents the synthesis of messenger RNA from DNA. 5,6-Dihydrothymidine is also able to inhibit cell growth in culture and can be used as a cell culture medium supplement.</p>Formula:C10H16N2O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:244.24 g/mol2-Deoxycytidine 3',5'-diphosphate
CAS:<p>2-Deoxycytidine 3',5'-diphosphate is an additive that is used in the production of DNA. It is a single-stranded nucleotide with a guanine base. 2-Deoxycytidine 3',5'-diphosphate has been shown to inhibit bacterial growth by reacting with hydrogen peroxide, which is produced during the process of oxidative phosphorylation. This reaction leads to the formation of reactive oxygen species, which damage DNA and cause cell death. The compound also binds to metal ions and prevents them from interacting with cellular components. 2-Deoxycytidine 3',5'-diphosphate can be used as a chromatographic agent for separating DNA fragments according to their size.</p>Formula:C9H15N3O10P2Purezza:Min. 95%Peso molecolare:387.18 g/mol3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione
CAS:3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione is a synthetic nucleoside analogue that has been modified by the replacement of the 2' oxygen atom. The phosphoramidite is used to produce 3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione in high purity and high quality. This product can be used as an antiviral agent and as an anticancer agent. It has also been shown to inhibit DNA synthesis and RNA synthesis.Formula:C12H13N3O5Purezza:Min. 95%Peso molecolare:279.25 g/molN4-Benzoyl-1-(a-D-mannopyranosyl)cytosine
N4-Benzoyl-1-(a-D-mannopyranosyl)cytosine is a modified deoxyribonucleoside that has antiviral and anticancer activities. It is a phosphoramidite, which can be converted to nucleosides using standard methods. N4-Benzoyl-1-(a-D-mannopyranosyl)cytosine is also an activator of the DNA polymerase enzyme and a high quality, novel anti-cancer drug.Formula:C17H19N3O7Purezza:Min. 95%Colore e forma:White to off-white powder.Peso molecolare:377.35 g/mol6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt
CAS:6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is a modified nucleoside that has anticancer activity. It is phosphorylated to the corresponding nucleotide in vivo and inhibits the growth of cancer cells. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt has a novel structure and can be used as an activator for ribonucleotides or deoxyribonucleotides. It is also used as a component in DNA synthesis, which may be due to its ability to inhibit viral RNA replication. This drug can be synthesized through chemical reactions that involve diphosphate, nucleosides, and phosphoramidites. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is not currently available on the market; however, it canFormula:C17H16N5Na2O9PSPurezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:543.36 g/mol(+)-Emtricitabine
CAS:Emtricitabine is a synthetic nucleoside analog of cytidine. It is used in the treatment of HIV infection and hepatitis B virus infection. Emtricitabine binds to human DNA polymerase, preventing the incorporation of viral DNA into the host cell's genome. This prevents the virus from multiplying and reproducing, thereby inhibiting the spread of HIV in humans. The drug has been shown to inhibit replication at all stages of HIV-1, including reverse transcription and integration into host cell DNA. Emtricitabine also inhibits replication of other viruses such as herpes simplex virus type 1 (HSV-1) and hepatitis C virus (HCV). Emtricitabine is a prodrug that must be activated by phosphorylation before it can be incorporated into DNA. This activation requires tenofovir alafenamide hemifumarate as an activator, which is an experimental drug with improved bioavailability, reduced renal clearance, andFormula:C8H10FN3O3SPurezza:Min. 95%Peso molecolare:247.25 g/molFluorescein-dt cep
CAS:Fluorescein-dt cep is a monophosphate nucleoside analog that is modified with an activated ester group. It is used as a prodrug for the treatment of influenza in humans. Fluorescein-dt cep has antiviral activity, which may be due to its ability to inhibit viral RNA synthesis. This agent also has anticancer activity and has been shown to kill leukemia cells by interfering with DNA synthesis. The chemical name for fluorescein-dt cep is 1-(2,6-dichloro-4-(5,7-dimethoxy-4-methylpyridiniumyl)phenyl)cytosine monophosphate. Fluorescein-dt cep is also known by the following synonyms: 1-(2,6-Dichloro-4-(5,7-dimethoxyquinoliniumyl)phenyl)-1H-[1,3]dioxFormula:C79H89N6O17PPurezza:Min. 95%Peso molecolare:1,425.6 g/molcis-Zeatin-o-glucoside riboside
CAS:<p>Cis-Zeatin-o-glucoside riboside is a plant metabolite that belongs to the class of phenylpropanoids. It is the product of the conversion of zeatin by a polyphenol oxidase. Cis-Zeatin-o-glucoside riboside has been found in plants, such as Eucomis and Alnifolia, at levels ranging from 0.2 to 1%. This metabolite is also present in animal tissues, such as rat brain and bovine mammary gland. The metabolic pathway for cis-Zeatin-o-glucoside riboside has been elucidated through tissue culture experiments with Eucomis and 24-epibrassinolide. The biosynthesis of this metabolite involves a two step process: first, an oxidative cleavage of zeatin to indole-3-acetyl l -aspartic acid and then conversion to</p>Formula:C21H31N5O10Purezza:Min. 95%Peso molecolare:513.5 g/molO6-Chlorophenyl-I ce-phosphoramidite
CAS:<p>Please enquire for more information about O6-Chlorophenyl-I ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C52H64ClN6O8PSiPurezza:Min. 95%Peso molecolare:995.6 g/mol(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-d
CAS:(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate (2'R)-N-benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate) is a modified nucleoside that is an antiviral, anticancer, and activator of DNA synthesis. It has been shown to be the first synthetic nucleotide analogue to have significant activity against HIV in vitro. The synthesis of this compound starts with the diphosphate or monophosphate form of cytidine. The phosphate group is removed and replaced with a 2'R benzoyl group. This process is followed by fluorination and methylation steps. Finally, the 5' hydroxyl group is cleaved to give 2'R -N benzoyl 2'-deoxy-2'-fluoro-2'-Formula:C31H26FN3O7Purezza:Min. 95%Peso molecolare:571.55 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
CAS:<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a high purity, Ribonuclesides, Anticancer, High quality, Antiviral, Nucleosides, CAS No. 118380-84-0, Deoxyribonucleosides, Modified, monophosphate and Phosphoramidites. It is an important reagent for the synthesis of DNA and RNA oligonucleotides. This product has novel properties as an anticancer drug and antiviral agent.</p>Formula:C52H66N5O9PSiPurezza:Min. 95%Colore e forma:PowderPeso molecolare:964.19 g/mol3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester
Prodotto controllato3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester (AZT) is a novel nucleoside compound that is a phosphoramidite. AZT has antiviral activity against various DNA and RNA viruses, including HIV. It is also effective in the treatment of cancer. AZT inhibits viral replication by competitively inhibiting the incorporation of diphosphate into viral DNA or RNA. This process prevents the synthesis of new virus particles and the spread of infection to healthy cells. In addition, AZT may inhibit tumor growth by interfering with cell division and DNA synthesis.Formula:C23H26D3N5O13Purezza:Min. 95%Peso molecolare:586.52 g/molTFA-ap-dU
CAS:<p>TFA-ap-dU is a modified, ribonucleosides that are used in DNA synthesis. The polymerase chain reaction (PCR) technique can be used to generate a large number of copies of a specific sequence of nucleotides from the original DNA template. This product is used for antiviral and anticancer research. TFA-ap-dU has been shown to be effective against Hepatitis B virus and Human Immunodeficiency Virus (HIV). It is also an activator of DNA and RNA synthesis.</p>Formula:C14H14F3N3O6Purezza:Min. 95%Peso molecolare:377.27 g/molThymidine 5'- triphosphate-3'-monophosphate
CAS:Thymidine 5'-triphosphate-3'-monophosphate is a nucleoside that is used in the synthesis of DNA. It is an activator of anticancer drugs, and has been shown to have antiviral properties. Thymidine 5'-triphosphate-3'-monophosphate can be used for the treatment of viral diseases such as herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and human immunodeficiency virus (HIV) infection. This nucleoside also plays a role in the prevention of tumor growth and metastasis because it inhibits DNA synthesis.Formula:C10H18N2O17P4Purezza:Min. 95%Peso molecolare:562.15 g/mol2-Chloro-3-deazaadenosine
CAS:<p>2-Chloro-3-deazaadenosine is an antiviral drug that inhibits the synthesis of DNA by acting as a competitive inhibitor for adenosine. It has been shown to be effective in the treatment of hepatitis B virus and herpes simplex virus infections. 2-Chloro-3-deazaadenosine prevents the incorporation of the natural nucleoside adenosine into DNA, which leads to inhibition of viral replication and cell division. This drug also has been shown to inactivate liver cells in bovines, which may account for its toxicity. The synthesis of 2-chloroadenosine is difficult and laborious due to its glycosylation, making it more expensive than other analogues that are more easily synthesized.</p>Formula:C11H13ClN4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:300.7 g/mol6-Chloropurine-9-b-D-glucoside
CAS:<p>6-Chloropurine-9-b-D-glucoside is a nucleoside that belongs to the family of modified nucleosides. It is used as an activator and a phosphoramidate in the synthesis of oligonucleotides. 6-Chloropurine-9-b-D-glucoside is also used in anticancer therapy because it inhibits DNA, RNA, and protein synthesis. 6CPG has antiviral activity against herpes virus and other viruses. This compound has been shown to have antiinflammatory activities by inhibiting the production of prostaglandins. 6CPG is also classified as a carcinogen by the International Agency for Research on Cancer (IARC).</p>Formula:C11H13CIN4O5Purezza:Min. 95%Peso molecolare:420.16 g/mol4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite
4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite is a novel, modified nucleoside with antiviral activity. It is activated by the addition of a DMT group to its 5' end and has an anticancer effect. The monophosphate form of 4-(2-Cyanoethylthio)-5'-O-DMT-thymidine 3'-CE phosphoramidite has been shown to inhibit viral DNA synthesis in vitro and to be cytotoxic against human cancer cell lines. 4-(2-Cyanoethylthio)-5'-O-DMT- thymidine 3'-CE phosphoramidite is a high quality, high purity product that can be used as a nucleoside or nucleotide in anticancer drugs.Formula:C43H52N5O7PSPurezza:Min. 95%Peso molecolare:813.96 g/molN6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:<p>N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel, modified, activator with antiviral and anticancer properties. It is the monophosphate of the acetylated 2'-deoxyadenosine 3'-cyanoethylphosphoramidite and has been shown to be effective in inhibiting DNA synthesis in cell cultures. This product is synthesized using high purity reagents and purification techniques.</p>Formula:C42H50N7O7PPurezza:Min. 95%Colore e forma:SolidPeso molecolare:795.86 g/molCarbodine
CAS:Carbocyclic analog of cytidineFormula:C10H15N3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:241.24 g/mol2’-Chloro-2’-deoxyadenosine
CAS:<p>2’-Chloro-2’-deoxyadenosine (2CDA) is a synthetic nucleoside analogue that is used as an antineoplastic agent for the treatment of non-Hodgkin lymphoma and histiocytic lymphoma. It is typically used in combination with other cytotoxic drugs. 2CDA has been shown to be effective against resistant tumor cell lines and has been used to treat patients with metastatic breast cancer, Hodgkin lymphoma, and multiple myeloma. The drug can cause thrombocytopenia, which may be due to its effects on platelets or bone marrow cells. Other toxicities include bone marrow suppression, nausea, vomiting, diarrhea, anorexia, and liver damage. Patients who are at risk for these toxicities should be closely monitored.</p>Formula:C10H12ClN5O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:285.69 g/mol2',3'-O-Isopropylidene-6-thioinosine
CAS:<p>2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.<br>2',3'-O-Isopropylidene-6-thioinos</p>Formula:C13H16N4O4SPurezza:Min. 95%Peso molecolare:324.36 g/molN4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It has been synthesized and purified by using the latest technology. It is a monophosphate, which is used in the synthesis of DNA, RNA, and other nucleic acids. It can be used for anticancer research and as a pharmaceutical intermediate.Formula:C52H74N5O10PSiPurezza:Min. 95%Colore e forma:White/Off-White SolidPeso molecolare:988.23 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is an activator of DNA polymerase. It has been shown to be a potent inhibitor of viral replication and an anticancer agent in vitro. The compound has also been shown to inhibit the growth of tumor cells in vivo. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Rp-oxazaphospholidine is a novel nucleoside analogue that has not been previously reported.Purezza:Min. 95%5'-O-Benzoyl-2'-deoxyuridine
CAS:5'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is a component of DNA. 5'-O-Benzoyl-2'-deoxyuridine is used as an antiviral agent and for the treatment of some cancers, including lymphomas, leukemia, and certain types of solid tumors. It has also been shown to be effective in the treatment of hepatitis B virus infection. This compound inhibits viral replication by competing with natural nucleosides for incorporation into DNA and RNA. 5'-O-Benzoyl-2'-deoxyuridine binds to double helix DNA at the groove between adenine and thymine bases and prevents further binding of nucleotides to this site. It also inhibits viral DNA synthesis by preventing conversion of ribonucleotides to deoxynucleosides. This drug is not active against bacteria or fungi; however, it can cause serious side effects such as pancreatitis and liver toxicity.Formula:C16H16N2O6Purezza:Min. 95%Peso molecolare:332.32 g/molN4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite
Nucleoside phosphoramidite used in oligonucleotide synthesisFormula:C49H58N5O10PPurezza:Min. 95%Peso molecolare:907.99 g/molRef: 3D-PB63464
25gPrezzo su richiesta50gPrezzo su richiesta100gPrezzo su richiesta250gPrezzo su richiesta2-(Aminomethyl)pyrimidine oxalate
CAS:<p>2-(Aminomethyl)pyrimidine oxalate is a substance that can be found in cicer arietinum. This compound has been shown to be tumorigenic, and it is hypothesized that the tumorigenicity of this compound is due to its ability to recombine with DNA and expressed genes, which may lead to the development of tumors. 2-(Aminomethyl)pyrimidine oxalate has been shown to activate translation of genes that are involved in tumorigenesis. The gene product which has been identified as being activated by 2-(aminomethyl)pyrimidine oxalate is called rhizogenes. Rhizogenes have been shown to have virulent phenotypes when exposed to cicer arietinum. With all these properties, it is believed that 2-(aminomethyl)pyrimidine oxalate may cause cancer or other harmful effects on organisms.br><br>br></p>Formula:C5H7N3·C2H2O4Purezza:Min. 95%Peso molecolare:199.16 g/molN6-Acetyl-2'-deoxy-5'-O-DMT-adenosine
<p>N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to inhibit the replication of HIV in vitro and in vivo, and also inhibits the replication of hepatitis B virus. N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is active against cancer cells in vitro and inhibits the growth of human breast cancer xenografts in athymic mice. This compound also has high purity, high quality, and novel properties.</p>Formula:C33H33N5O6Purezza:Min. 95%Peso molecolare:595.65 g/molBis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite
CAS:Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite is a potent inhibitor that targets human immunodeficiency virus (HIV) and cancer. It acts as an analog of substrates for human plasma membrane kinases, which are essential for the replication of HIV. Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite has been shown to inhibit lung metastasis in mice, indicating its potential therapeutic use against cancer. This compound also exhibits inhibitory activities against Escherichia coli alkaline phosphatase and other enzymes, suggesting its pharmacological activity may extend beyond HIV and cancer treatment. Overall, Bis(2-cyanoethyl)-N,N-diisopropyl phosphoramidite is a promising inhibitor with potential applications in multiple fields.Formula:C12H22N3O2PPurezza:Min. 90 Area-%Colore e forma:Slightly Yellow Clear LiquidPeso molecolare:271.3 g/mol9-Deaza-2'-deoxyguanosine
CAS:9-Deaza-2'-deoxyguanosine is a novel synthetic nucleoside that activates the ribonucleotide reductase enzyme. The activation of this enzyme was found to be dependent on the presence of diphosphate, which is a cofactor for this enzyme. 9-Deaza-2'-deoxyguanosine has been shown to inhibit the growth of cells in culture and to induce apoptosis. It also inhibits viral replication by interfering with the synthesis of viral DNA. In addition, 9-Deaza-2'-deoxyguanosine can inhibit tumor cell proliferation and promote differentiation in vitro.Formula:C11H14N4O4Purezza:Min. 95%Peso molecolare:266.25 g/mol5-O-Tritylinosine
CAS:5-O-Tritylinosine is a modified nucleoside that has shown anticancer and antiviral properties. It is the monophosphate ester of 5-methyluracil and has been shown to inhibit DNA synthesis in vitro. 5-O-Tritylinosine has also been shown to inhibit the replication of herpes simplex virus type 1, which may be due to its ability to inhibit viral DNA polymerase.Formula:C29H26N4O5Purezza:Min. 95%Peso molecolare:510.54 g/molBiotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
<p>Biotin-5-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a monoclonal antibody. It is used in the diagnosis of lung cancer. The antibody binds to markers present on the tumor cells and can be detected by immunohistochemistry (IHC) or immunofluorescence (IF). The antibody may also be used to identify submucosal tumors that are not palpable.</p>Formula:C22H34N5O17P3S·xLiPurezza:Min. 95%Peso molecolare:765.52 g/mol2-Amino-2'-deoxyadenosine 5'-triphosphate
CAS:2-Amino-2'-deoxyadenosine 5'-triphosphate (2ADP) is a nucleotide that is involved in the synthesis of DNA. It is an important part of the process of DNA replication, as it provides the necessary energy to drive reactions that synthesize new DNA strands. It also has anti-viral properties and can be used as a molecular probe to detect acid. 2ADP is detectable with most common detection methods, such as UV/visible absorbance spectroscopy, fluorescence spectroscopy, and chemiluminescence. It is one of the three triphosphates found in cells and can be used to polymerize RNA by adding ribose phosphate groups to the sugar molecule in RNA. This reaction requires ATP, which produces AMP, ADP, and 2ADP.Formula:C10H17N6O12P3Purezza:Min. 95%Peso molecolare:506.2 g/mol5-Hydroxymethyl-dc ce-phosphoramidite (hmdc)
CAS:<p>Please enquire for more information about 5-Hydroxymethyl-dc ce-phosphoramidite (hmdc) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C50H57N6O9PPurezza:Min. 95%Peso molecolare:917 g/mol5-Phenylcytidine
CAS:5-Phenylcytidine is a nitro compound that is used as an antiviral agent. It inhibits the replication of the virus by interfering with viral DNA synthesis and preventing the assembly of viral proteins. 5-Phenylcytidine is also capable of inhibiting influenza A virus in vitro at concentrations below 1 μM and has been shown to inhibit herpes simplex virus type 1 (HSV-1) in cell culture. The antiviral activity of 5-phenylcytidine may be due to its ability to form a stable reaction product with cytosine in alkaline conditions, which prevents the incorporation of this nucleobase into DNA or RNA.Purezza:Min. 95%8-Methoxyadenosine
CAS:8-Methoxyadenosine is an acidic adenosine that acts as a competitive antagonist of the A1 receptor. It has a high affinity for this receptor and blocks the binding of adenosine to the receptor, thereby inhibiting its function. 8-Methoxyadenosine is also a competitive antagonist of the uridine nucleotide, which inhibits enzymatic catalysis by ribonucleoside kinase and ribonucleotide reductase. It has been shown to have properties similar to those of other pyrimidine nucleosides such as cytidine, thymine, and uridine. This molecule has a hydroxyl group in its structure, which is essential for binding to these enzymes. 8-Methoxyadenosine also has a phosphate group in its structure, which is necessary for the synthesis of DNA or RNA from deoxyribonucleotides. The benzoate group in 8-methoxyadenosine's structure makesPurezza:Min. 95%5’-Azido-2’,5’-dideoxyuridine
CAS:<p>5’-Azido-2’,5’-dideoxyuridine (5ADU) is a pyrimidine nucleoside that has been used to treat cancer. It is converted to 5-azidouracil which inhibits the synthesis of thymidylate, an essential component of DNA. 5ADU is also active against herpes virus and can be used as an antiviral agent. This drug has been shown to protect against radiation damage by inhibiting the formation of free radicals. The protonation of 5ADU leads to a stereochemical rearrangement that prevents the formation of free radicals. 5ADU does not inhibit bacterial enzymes, but it does have some effect on viruses, such as herpes virus, because they contain DNA or RNA similar to human cells.</p>Formula:C9H11N5O4Purezza:Min. 95%Peso molecolare:253.21 g/molIsowyosine
CAS:<p>Isowyosine is a protein that catalyzes the synthesis of purines, which are essential for DNA synthesis and repair. Isowyosine is found in mammalian cells, where it has been observed to play a role in the translation of messenger RNA (mRNA). Isowyosine also plays a role in the synthesis of viral proteins and viral replication. It has been shown to be active against various viruses, including herpes simplex virus and influenza virus. Isowyosine may also have anti-cancer properties due to its ability to inhibit tumor growth.</p>Formula:C14H17N5O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:335.32 g/mol5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt
<p>5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt is a modified nucleoside with anticancer activity. It is a diphosphate that can be used for the synthesis of DNA and RNA. This product is synthesized by the reaction of 5'-O-dimethoxytritylthymidine (5'-DMTT), 2'-O-(2-methoxyethyl)hydroxylamine hydrochloride, and succinic anhydride in the presence of triethylamine. The product is purified by column chromatography, followed by recrystallization from hot acetonitrile. CAS No.: 102972-73-0</p>Formula:C49H52N5O13·C6H16NPurezza:Min. 95%Peso molecolare:1,021.16 g/molN4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine
<p>N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine is a nucleoside that is used as an antiviral and anticancer agent. It is a modified deoxyribonucleoside that has antiviral activity against HSV-1, HSV-2, and HIV. N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine also has anticancer effects against leukemia cells in mice. This drug is synthesized from 2′,3′,5′triacetyladenosine by the reaction of 4-(1H)-benzoyloxymethyl)phenylacetic acid with triethylamine and levulinic acid chloride.</p>Formula:C21H23N3O7Purezza:Min. 95%Peso molecolare:429.43 g/mol8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine
Prodotto controllato<p>8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine is a novel, diphosphate nucleoside with antiviral and anticancer activity. It has been shown to activate the transcription of genes that are involved in cell growth and differentiation. This drug also inhibits the synthesis of viral DNA by binding to the viral DNA polymerase, thereby inhibiting its function. 8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine can be used as a phosphoramidite for the preparation of oligonucleotides for use in gene therapy.</p>Formula:C22H17N6O4D5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:439.48 g/mol3'-O-Allyluridine
<p>3'-O-Allyluridine is a nucleoside that has antiviral, anticancer, and antibacterial activities. 3'-O-Allyluridine is an activator of RNA polymerase and is used to synthesize DNA in vitro. It can be used as a substrate for phosphoramidites in the synthesis of oligonucleotides with modified backbones. 3'-O-Allyluridine has been shown to inhibit the growth of cancer cells by blocking the synthesis of DNA and RNA. The drug also inhibits the production of ribonucleases, which are enzymes that break down RNA in cells.</p>Formula:C12H16N2O6Purezza:Min. 95%Peso molecolare:284.27 g/molN,7-Dimethyl- 2'- O- methylguanosine
CAS:<p>N,7-Dimethyl-2'-O-methylguanosine (DMOG) is a modified nucleoside with antiviral and anticancer properties. DMOG can be used as an activator of transcription, which activates the synthesis of viral RNA and dsDNA. This compound has shown to inhibit the activity of HIV by preventing reverse transcriptase from synthesizing DNA from viral RNA. It also inhibits tumor cell proliferation by inhibiting DNA synthesis and protein synthesis. DMOG is synthesized in high purity by chemical phosphoramidite chemistry.</p>Formula:C13H20N5O5Purezza:Min. 95%Peso molecolare:326.33 g/mol5-Fluorocytosine arabinoside
CAS:<p>5-Fluorocytosine arabinoside (5FCA) is an analog of fluorocytosine and a degradable prodrug that is converted to fluorouracil (5FU) in the human liver. It acts as an inhibitor of DNA synthesis and has been used for the treatment of leukemias. 5-Fluorocytosine arabinoside is rapidly degraded by tissue culture cells, which may be due to its reactive functional groups. The inhibitory activity of this drug against cell culture was found to be minimal at low concentrations and reached a maximum at concentrations greater than 1 mM. The affinity ligands for this compound are reactive functional groups such as sulfhydryl, hydroxyl, and carboxyl groups, but not ester or amide bonds. This drug can be used in the synthesis of affinity ligands with a reactive functional group.</p>Formula:C9H12FN3O5Purezza:Min. 95%Peso molecolare:261.21 g/mol3'-Azido-2'-deoxy-5'-O-DMT-thymidine
CAS:3'-Azido-2'-deoxy-5'-O-DMT-thymidine is a novel and potent activator of ribonucleotide reductase. It has been shown to be an effective inhibitor of DNA synthesis and antiviral agent, with a low cytotoxicity profile. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine is synthesized from DMT, which is readily available in the form of its monophosphate or diphosphate. The compound has been shown to inhibit viral replication by inhibiting viral reverse transcriptase activity. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine also inhibits DNA synthesis in cancer cells.Formula:C31H31N5O6Purezza:Min. 95%Peso molecolare:569.61 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite is a novel, deoxynucleoside phosphoramidite with high purity and high quality. It has been used in the synthesis of anticancer agents, ribonucleotide analogues and antiviral agents. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite can be used as an activator for DNA polymerase to synthesize DNA molecule.</p>Formula:C53H68N5O9PSiPurezza:Min. 95%Peso molecolare:978.19 g/molAdenylyl-3'-5'-uridine ammonium salt
CAS:<p>Adenylyl-3'-5'-uridine ammonium salt is a novel antiviral agent that has been shown to inhibit the activity of viral DNA polymerase, RNA polymerase and reverse transcriptase. It is also an anticancer agent that can be used as a cytotoxic agent against leukemia and lymphoma cells. Adenylyl-3'-5'-uridine ammonium salt is synthesized by the reaction of adenosine monophosphate with uracil in the presence of phosphate and ammonia. This compound can then be converted to ribonucleosides or deoxyribonucleosides by phosphorylation.<br>SYNONYMS: AMP-uridine; AMP-U; UMP</p>Formula:C19H24N7O12PPurezza:Min. 95%Peso molecolare:573.41 g/molN6-(tert-Butylphenoxyacetyl)-2'-O-methyl-5'-O-DMT-adenosine 3'-CE phosphoramidite
N6-(tert-Butylphenoxyacetyl)-2'-O-methyl-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel anticancer, antiviral and antifungal agent. It is synthesized by reacting the nucleoside adenosine with tert-butyl phenoxyacetic acid to form an activated ester derivative which reacts with 2'-O-methyl 5'-O-DMT in the presence of a phosphoramidite reagent to form a DNA precursor. The modified nucleotide has been shown to have high purity and good quality, as well as high antiviral and anti-cancer activities.Formula:C53H64N7O9PPurezza:Min. 95%Peso molecolare:974.09 g/mol4’-a-C-Methyluridine
CAS:<p>4' - a-C-Methyluridine is a modified nucleoside that is used as a building block in the synthesis of DNA. It can be used for the treatment of viral infections and cancer. 4' - a-C-Methyluridine has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. 4' - a-C-Methyluridine also has anticancer activity, which may be due to its ability to inhibit proliferation of cells by blocking the synthesis of DNA and RNA.</p>Purezza:Min. 95%DdCTP trilithium
CAS:<p>2',3'-Dideoxycytidine-5'-triphosphate trilithium salt (ddCTP) is a nucleoside analogue that has been shown to inhibit the enzyme activity of DNA polymerase. The ddCTP is a prodrug, which is activated by phosphorylation catalyzed by cellular kinases and then hydrolyzed to its active form, dideoxycytidine triphosphate (ddCTP). This drug also inhibits the synthesis of DNA and RNA. In vitro studies have shown that ddCTP causes cell lysis in murine sarcoma virus-infected cells, although it does not affect uninfected cells. 2',3'-Dideoxycytidine-5'-triphosphate trilithium salt has been shown to be an effective inhibitor of HIV reverse transcriptase and HIV protease in biochemical assays. It has also been found to be an effective inhibitor of mouse monoclon</p>Formula:C9H13N3Li3O12P3Purezza:Min. 95%Colore e forma:LiquidPeso molecolare:468.96 g/mol
