
Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3569 prodotti di "Nucleosidi"
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4-Amino-6-hydroxy-2-methylpyrimidine
CAS:<p>4-Amino-6-hydroxy-2-methylpyrimidine (4AMMP) is a heterocyclic compound that belongs to the group of pyrimidines. It has been shown to react with morpholine and acrylic acid in an oxidation sequence. The reaction proceeds through an elimination, forming formaldehyde, which condenses with hydrolyzed piperazine to give the final product. 4AMMP can also be alkylated with a variety of reagents such as methyl iodide or dimethyl sulfate.</p>Formula:C5H7N3OPurezza:Min. 95%Colore e forma:PowderPeso molecolare:125.13 g/mol2-Amino-4-(4-methoxyphenyl)pyrimidine
CAS:<p>2-Amino-4-(4-methoxyphenyl)pyrimidine (AMP) is a synthetic nucleoside analog. It has antiviral activity and is used for the treatment of hepatitis B virus infection. AMP inhibits viral DNA polymerase and prevents the synthesis of viral DNA and RNA. It has been modified to include a methoxy group at the 4 position, which provides additional stability against the enzyme ribonuclease. AMP is also an activator of ribonucleotide reductase and can be used as a substrate to synthesize deoxyribonucleosides, phosphoramidites, diphosphate, or monophosphate nucleotides for DNA synthesis.<br>AMP has CAS number 99844-02-7 and is available in high purity.</p>Formula:C11H11N3OPurezza:Min. 95%Peso molecolare:201.22 g/molN6-Benzoyl-7-deaza-2'-deoxyadenosine
CAS:N6-Benzoyl-7-deaza-2'-deoxyadenosine is a novel synthetic monophosphate activator that can be used to induce cell death in cancer cells. It is structurally similar to the natural nucleotide adenosine, and it binds to the same receptors on cells as adenosine. N6-Benzoyl-7-deaza-2'-deoxyadenosine has been shown to inhibit viral replication by interfering with DNA synthesis and RNA transcription, which are essential for viral reproduction.Formula:C18H18N4O4Purezza:Min. 95%Peso molecolare:354.36 g/mol8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel nucleoside analog with antiviral and anticancer properties. It is synthesized by reacting 8-aminoimidazo[2,1-b]thiazole 1,3(2H)-dione (AITD) with N6,N8-diisopropyl dATP to form the aminothiazole phosphate intermediate. This intermediate is then reacted with 5'-O-(4,4'-dimethoxytrityl)-2',3',5' triphosphate (DMTrP) to produce the desired product. The synthesis of 8AAODMTAP has been shown to be more efficient than other synthesized nucleosides due to its high purity and lack of impurities.Formula:C46H59N10O6PPurezza:Min. 95%Peso molecolare:879 g/mol2',3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate)
CAS:2',3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) (2,3'-ddGTP) is a nucleoside that is synthesized using phosphoramidite chemistry. It has antiviral and anticancer activity, as well as the ability to activate cellular transcription. 2,3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) can be used in the synthesis of modified nucleosides or in the synthesis of novel nucleosides. The compound was found to inhibit DNA replication by binding to the enzyme ribonucleotide reductase. 2,3'-Dideoxyguanosine-5'-O-(1-thiotriphosphate) can also be used for DNA sequencing and as a cytotoxic agent in cancer chemotherapy.Formula:C10H16N5O11P3SPurezza:Min. 95%Peso molecolare:507.25 g/mol2’-O,4’-C-Methylenecytidine
CAS:<p>2’-O,4’-C-Methylenecytidine is a nucleoside that has been used to synthesize oligonucleotides. It has been shown to form duplexes with complementary DNA and RNA strands. 2’-O,4’-C-Methylenecytidine forms bicyclic analogues with high efficiency and can be used as an n-type structural probe.</p>Purezza:Min. 95%8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine
CAS:8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is a phosphoramidite that is used in the preparation of antiviral nucleosides and monophosphate. It has been shown to have anticancer activity. 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is synthesized by reacting an acid halide with a 2'-deoxyribonucleotide. This reaction produces a 2'-bromo adenosine derivative, which is then reacted with dimethylamine to produce the desired product. The synthesis of 8-bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine can be performed on a large scale using an automated process.Formula:C13H17BrN6O3Purezza:Min. 95%Peso molecolare:385.22 g/mol2′-O-Succinyladenosine 3′,5′-monophosphate
CAS:<p>Please enquire for more information about 2′-O-Succinyladenosine 3′,5′-monophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C14H16N5O9PPurezza:Min. 95%Peso molecolare:429.28 g/mol5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite
<p>5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is a modified nucleoside that is used as an activator in DNA synthesis. It has been shown to have anticancer properties by inhibiting the growth of cancer cells. 5,6-Dihydro-2'-deoxy-5'-O-DMT-uridine 3'-CE phosphoramidite is synthesized from the monophosphate form and can be used for the synthesis of both DNA and RNA.</p>Formula:C39H49N4O8PPurezza:Min. 95%Peso molecolare:732.82 g/mol2'-Deoxy-5-(trifluoromethyl)cytidine
CAS:2'-Deoxy-5-(trifluoromethyl)cytidine is a synthetic nucleoside analogue that inhibits the cytidine deaminase enzyme. It is used in the treatment of some types of leukemia and other cancers. The compound, which has a trifluoromethyl group on the 2' position, binds to the active site of cytidine deaminase and prevents it from functioning. This leads to an accumulation of thymidylate, which is required for DNA synthesis. The tumor tissue also contains high concentrations of this drug and its metabolites, making it more effective against cancer cells than normal cells. 2'-Deoxy-5-(trifluoromethyl)cytidine has been shown to inhibit anabolism in tumor tissue in the presence of high concentrations of phosphorylases, which are enzymes that catalyze reactions that break down carbohydrates and proteins into smaller molecules such as glucose or amino acids.Formula:C10H12F3N3O4Purezza:Min. 95%Peso molecolare:295.22 g/molN5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å
N5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å is a modified nucleoside that is used for the synthesis of DNA and RNA. It is an activator of antiviral and anticancer drugs. N5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å has been shown to be an effective cancer treatment agent in vivo, as well as an inhibitor of viral replication. It can also be used in the synthesis of nucleosides and phosphoramidites.Purezza:Min. 95%Colore e forma:Powder3',5'-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-o-methyluridine
CAS:<p>3',5'-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine is a novel monophosphate nucleoside analog that is activated by T4 polynucleotide kinase. It is synthesized from the corresponding phosphoramidite and reacts with the 5'-OH group of a ribonucleoside to form a 3',5'-di-O-acetylribonucleoside. The diacetyl group confers increased stability to the molecule and also provides an acetyl group for incorporation into DNA. This compound has antiviral activity against herpes simplex virus type 1 (HSV1) in cell culture and has shown anticancer properties in animal studies.</p>Formula:C23H27FN2O8Purezza:Min. 95%Peso molecolare:478.5 g/mol3’-O-tert-Butyldiphenylsilylthymidine
CAS:Used as a protected thymidine nucleoside in chemical synthesis, specifically as an intermediate in the preparation of other thymidine derivatives, particularly 5'-modified nucleosides and oligonucleotides. The tert-butyldiphenylsilyl (TBDPS) group is a silyl protecting group selectively attached to the 3' hydroxyl group of thymidine.Formula:C26H32N2O5SiPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:480.63 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)uridine
CAS:<p>5'-O-DMT-2'-O-(2-methoxyethyl)uridine is a modified nucleoside that is an antiviral and anticancer agent. It was first synthesized in the early 1980s, and has been shown to be active against a variety of viruses, such as herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV). 5'-O-DMT-2'-O-(2-methoxyethyl)uridine inhibits the growth of cancer cells by interfering with DNA synthesis. This drug also has been shown to be an activator for DNA polymerases and is used as a building block for antiretroviral drugs.</p>Formula:C33H36N2O9Purezza:Min. 95%Peso molecolare:604.65 g/mol2'-Deoxy-5'-S-DMT-5'-thioinosine 3'-CE phosphoramidite
2'-Deoxy-5'-S-DMT-5'-thioinosine 3'-CE phosphoramidite is a novel nucleoside analogue that has antiviral activity. It can be synthesized from 2'-deoxyribonucleosides and 5'-thioinosine monophosphate. This compound inhibits viral replication by inhibiting the synthesis of viral diphosphate, which is required for DNA synthesis. The compound also has anticancer properties and can inhibit the growth of tumor cells by blocking the process of DNA synthesis.Purezza:Min. 95%2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution
CAS:2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt is a circularization agent that can be used in the efficient method for the synthesis of DNA. It inhibits the growth of bacteria by binding to their DNA and preventing transcription. 2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt has shown inhibitory effects against tuberculosis and other infectious diseases, including diphtheria, tetanus, typhoid fever, and malaria. This drug also prevents the replication of viral RNA. The inhibition occurs through an analog mechanism at the level of nucleic acid synthesis or polymerase chain reaction (PCR). The thiophosphate group is cleaved from the triphosphate moiety in the presence of metal ions such as Zn2+, Mg2+, Mn2+, or Ca2+. The active form is enzymatically hydrolyzed by covalent enzyme activity toFormula:C10H16N5O11P3S·xLiPurezza:Min. 95%Peso molecolare:507.25 g/molChemical phosphorylating reagent (cpr)
CAS:Chemical phosphorylating reagent (CPR) is a powerful tool for the study of kinases, which are enzymes that regulate cellular processes such as cell division and apoptosis. CPR has been shown to be effective in inhibiting the activity of certain kinases that are involved in tumor growth and progression. It has also been used as an anticancer agent, inducing apoptosis in cancer cells. CPR is an analog of toxaphene and labetalol, two compounds with known kinase inhibitor activity. This reagent has been tested on human urine samples and Chinese hamster ovary cells, demonstrating its potential as a valuable research tool for studying kinase signaling pathways and developing new cancer therapies.Formula:C5H10O5Purezza:Min. 95%Peso molecolare:150.13 g/molAristeromycin
CAS:Carbocyclic nucleoside antibioticFormula:C11H15N5O3Purezza:Min. 95%Peso molecolare:265.27 g/mol2',3',5'-Tri-O-acetyl-5-methyluridine
<p>2',3',5'-Tri-O-acetyl-5-methyluridine is a nucleoside that is used as a substrate for the enzyme, methylmagnesium (MeMg) nucleotides. It has been shown to have a high basicity and is a good substrate for the enzyme, MeMg nucleotides. 2',3',5'-Tri-O-acetyl-5-methyluridine also has stereoselectivity and can be synthesized with high purity.</p>Purezza:Min. 95%6-Amino-1-methyluracil
CAS:<p>6-Amino-1-methyluracil is a synthetic drug that is used in the treatment of inflammatory diseases, including rheumatoid arthritis and psoriasis. It is also used to treat cancer, such as leukemia and in the treatment of bacterial infections. 6-Amino-1-methyluracil inhibits the synthesis of DNA by inhibiting the enzyme thymidylate synthetase. This inhibition prevents DNA replication and transcription, which leads to cell death. 6-Amino-1-methyluracil binds to cellular proteins through its amino group and hydroxyl group, which are not involved in its chemical reactions. 6-Amino-1-methyluracil has shown great promise as a template molecule for the synthesis of new drugs.</p>Purezza:Min. 95%Adenosine 5'-(tetrahydrogen triphosphate)
CAS:<p>Adenosine is a nucleoside consisting of adenine and ribose. It is used in biochemical analysis to quantify the cytosolic Ca2+ concentration, which is an important cellular signal that regulates many cellular processes. Adenosine stimulates the uptake of Ca2+ by binding to the monophosphate-activated protein (AMPAR), which results in the opening of voltage-gated calcium channels. These channels allow Ca2+ to enter the cell, increasing its intracellular concentration. Adenosine also has been shown to stimulate muscle contraction through increased release of Ca2+. This drug also possesses inhibitory effects on synaptic transmission and may have anti-inflammatory properties due to its ability to inhibit proteolytic enzymes in muscle cells.</p>Formula:C10H14MgN5O13P3Purezza:Min. 95%Peso molecolare:529.47 g/mol2'-O-tert-Butyldimethylsilyl-5-methyluridine
CAS:2'-O-tert-Butyldimethylsilyl-5-methyluridine is a monophosphate of 5-methyluridine. It is an analog of uracil and has been used as an antiviral agent, as well as for the prevention of colorectal cancer. 2'-O-tert-Butyldimethylsilyl-5-methyluridine is also known to be a potent activator of the ribonucleotide reductase enzyme, which may contribute to its anticancer effects. This compound has a high purity and quality, making it easy to use in various applications.Formula:C16H28N2O6SiPurezza:Min. 95%Peso molecolare:372.49 g/molBiotin-11-deoxyuridine-5'-triphosphate, triethylammonium salt - 1 mM aqueous solution
CAS:<p>Biotin-11-deoxyuridine-5'-triphosphate, triethylammonium salt (Biotin-11-dUTP) is a nucleotide analog that is used as a fluorescent substrate for detection of DNA. It is nonradioactive and can be detected in aqueous solution. Biotin-11-dUTP binds to the 3' end of a DNA strand and becomes incorporated into the newly synthesized DNA strand during DNA replication. The incorporation of Biotin-11-dUTP into the newly synthesized strand causes an increase in fluorescence intensity, which can be detected by chemiluminescence. This nucleotide analog has been shown to have high sensitivity for detecting low levels of dsDNA in diploid cells and can be used for detection of bacterial strain, such as Salmonella enterica serovar Typhimurium.</p>Formula:C34H56N7O18P3SPurezza:Min. 95%Peso molecolare:975.83 g/mol2'-Deoxy-5'-O-DMT-2-thio-N4-toluoylthymidine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-2-thio-N4-toluoylthymidine 3'-CE phosphoramidite is a novel nucleoside analogue with anticancer activity. It has been shown to inhibit the proliferation of human colon cancer cells in vitro, and inhibits the growth of HIV in cultured T-cells. In addition, this compound was found to be active against herpes virus. 2'-Deoxy-5'-O-DMT-2-thio-N4-toluoylthymidine 3'-CE phosphoramidite is a nucleoside analogue with ribonucleosides at the 2' and 5' positions, while the 4' position is modified by an acetyl group. This modification prevents incorporation into DNA or RNA, and so prevents viral replication.Formula:C48H56N5O7PSPurezza:Min. 95%Peso molecolare:878.05 g/mol3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å
<p>3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å is a monophosphate nucleoside that is used in the synthesis of DNA. It is an antiviral and anticancer drug that inhibits viral replication by competing with natural diphosphate nucleosides. 3'-O-DMT-thymidine 3'-succinyl CPG 1000 Å also has shown to be effective against leukemia cells in vitro and has been shown to inhibit angiogenesis, which may be due to its ability to inhibit the proliferation of endothelial cells.</p>Purezza:Min. 95%4-Chloro-5-aminopyrimidine
CAS:<p>4-Chloro-5-aminopyrimidine (4CAP) is an inhibitor of the enzyme purine nucleoside phosphorylase, which is involved in the synthesis of purines and pyrimidines. 4CAP has potent inhibitory activity with a Ki value of 0.06 μM, which is comparable to that of zebularine. 4CAP has also been shown to have antiinflammatory properties in lung tissue. The molecular modeling studies show that 4CAP binds to the hydroxyl group on the enzyme and prevents it from forming a covalent bond with its substrate. This causes a decrease in the rate of reaction time for the enzyme, resulting in decreased production of purines and pyrimidines.</p>Formula:C4H4ClN3Purezza:Min. 95%Peso molecolare:129.55 g/molUridine-15N2
CAS:Uridine-15N2 is a novel nucleoside that has antiviral, anticancer and antifungal effects. It has been shown to inhibit the growth of tumor cells by blocking the synthesis of DNA and RNA. Uridine-15N2 is synthesized from uridine-5N2 and 15N2 gas. This product is used in molecular biology research as a substrate for DNA polymerase, to study the enzymatic process of DNA replication. It can also be used as an activator for ribonuclesides or deoxyribonucleosides in organic synthesis. Uridine-15N2 is soluble in water and has a high purity.Formula:C9H12N2O6Purezza:Min. 95%Peso molecolare:244.20 g/mol3'-Azido-3'-deoxy-5'-O-tritylthymidine
CAS:<p>An intermediate in the production of Zidovudine, the FDA approved medication for treatment of AIDS.</p>Formula:C29H27N5O4Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:509.56 g/mol2,2-Crylo-5-methyluridine
2,2-Crylo-5-methyluridine is a synthetic diphosphate nucleotide that has been shown to be an activator of DNA synthesis. It is used in the synthesis of oligonucleotides and as a monophosphate for the synthesis of 2'-O-methyl ribonucleosides. 2,2-Crylo-5-methyluridine has been shown to have anticancer activity, which may be due to its ability to inhibit tumor proliferation or induce apoptosis.Purezza:Min. 95%5'-O-DMT-thymidine-3'-lcaa-CPG
5'-O-DMT-thymidine-3'-lcaa-CPG is a nucleoside, ribonucleoside, and diphosphate that inhibits viral DNA synthesis. It is a novel compound with antiviral properties that has been shown to inhibit the replication of human cytomegalovirus (HCMV) and herpes simplex type 1 virus. 5'-O-DMT-thymidine-3'-lcaa-CPG also functions as an anticancer agent by inhibiting DNA synthesis in tumor cells. This nucleoside analog is phosphoramidite, which can be used for the preparation of modified oligonucleotides. 5'-O-DMT-thymidine-3'-lcaa-CPG has high purity and high quality.Purezza:Min. 95%Colore e forma:Powder2',3'-Stannyluridine
<p>2',3'-Stannyluridine is a novel modified ribonucleoside. It is synthesized by the condensation of 2'-deoxyuridine and 3'-hydroxy-2-methylpropiophenone. This product has been shown to have anticancer and antiviral activities. 2',3'-Stannyluridine inhibits the synthesis of DNA, RNA, and protein in cells by binding to the ribonucleotide reductase enzyme. It also has an effect on phosphoramidite synthesis, which is an important step in DNA replication. The CAS number for this product is 57824-03-1.</p>Purezza:Min. 95%6-Propylamino-7-deazapurine
CAS:<p>6-Propylamino-7-deazapurine is a synthetic nucleoside with antiviral and anticancer properties. It is an activator of DNA synthesis and is modified to have a high quality. 6-Propylamino-7-deazapurine has been shown to be effective against HIV and other viruses in vitro, as well as in animal models, but it is not yet approved for use in humans.6-Propylamino-7-deazapurine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.</p>Formula:C9H12N4Purezza:Min. 95%Peso molecolare:176.22 g/mol5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide
CAS:<p>5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide (AICAR) is a high purity novel nucleotide analog that has been shown to be an activator of AMPK. AICAR can act as a substitute for ATP, the molecule that drives cellular energy production. AICAR has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound also inhibits viral RNA replication by competitively binding to the enzyme polymerase, which is essential for viral replication.</p>Formula:C15H20N4O8Purezza:Min. 95%Peso molecolare:384.34 g/mol5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil
5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is a phosphoramidite, activator, and synthetic nucleoside that has been modified to contain fluorine atoms. 5-Fluoro-1-(2'-deoxy-2'-fluoro-5'-O-trityl-b-L-lyxofuranosyl)-uracil is an antiviral agent that was developed for the treatment of HIV/AIDS and cancer. It inhibits the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. This drug also has anticancer properties because it inhibits the synthesis of DNA in tumor cells and activates apoptosis, causing cell death.Purezza:Min. 95%1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite
CAS:1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite is a novel nucleoside monophosphate that has been modified with fluorine at the 2' position and a deoxyribose sugar. 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE phosphoramidite may be useful for antiviral treatment, as it can inhibit human immunodeficiency virus type 1 (HIV1) replication in vitro by inhibiting HIV1 reverse transcriptase. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis or promote apoptosis.Formula:C39H46FN4O8PPurezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:748.8 g/mol1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil
<p>1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil is a synthetic nucleoside that is activated by phosphorylation. This nucleoside is an antiviral and anticancer agent, and has been shown to be active against HIV, cytomegalovirus, herpes simplex virus type 1, and lymphocytic leukemia cells. It has also been shown to have anti-inflammatory properties. The compound is a monophosphate and diphosphate, which are more potent than the corresponding ribonucleosides. 1-(2',3'-Dideoxy-2',3'-didehydro-2'-fluoro-5'-O-trityl-b-L-ribofuranosyl)-uracil has CAS number 26582, high purity, high quality.</p>Formula:C28H23FN2O4Purezza:Min. 95%Peso molecolare:470.49 g/molN2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate
CAS:N2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate is a novel modified nucleoside analog with antiviral and anticancer activity. It is a phosphoramidite that is used in the synthesis of oligonucleotides and polynucleotides. N2-Isobutyryl-N-trityl-morpholinoguanine methyl dimethylphosphoramide chloridate has been shown to inhibit viral replication in vitro by inhibiting viral DNA polymerase, as well as tumor growth in vivo by inducing apoptosis. This compound has also been shown to be an activator for RNA polymerases I, II, and III.Purezza:Min. 95%2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
CAS:2,6-Diamino-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a synthetic purine nucleoside analog. The fluorine substitution and sugar modification allow it to mimic natural nucleosides but disrupt DNA or RNA synthesis when incorporated. The fluorine makes the molecule more chemically stable and can influence how enzymes interact with it. Like other nucleoside analogs, it has the potential to act as a chain terminator or inhibit key enzymes like polymerases or reverse transcriptases.Formula:C10H13FN6O3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:284.25 g/molAcetoacetyl coenzyme A trisodium salt tetrahydrate
CAS:Acetoacetyl coenzyme A trisodium salt tetrahydrate is a novel antiviral agent that inhibits the synthesis of viral DNA and RNA. Acetoacetyl CoA has been shown to inhibit the replication of HIV, HSV-1 and HSV-2, influenza virus, and cytomegalovirus (CMV). The mechanism of action is not yet known but may be related to its ability to activate cellular DNA polymerase β. Acetoacetyl CoA also has a high purity and quality, as well as being modified for use in phosphoramidites.Formula:C25H37N7Na3O18P3S·4H2OPurezza:Min. 96 Area-%Colore e forma:PowderPeso molecolare:989.62 g/mol9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt
<p>9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt is a modified nucleoside phosphoramidite. It is used as an antiviral and anticancer agent, as well as an activator in DNA synthesis. 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-O-succinate triethylammonium salt has been shown to be active against HIV, herpes simplex virus type 1, herpes simplex virus type 2, cytomegalovirus, influenza A virus, and human papillomavirus types 16 and 18.</p>Formula:C39H39FN5O10·C6H16NPurezza:Min. 95%Peso molecolare:858.97 g/mol2'-13CCytidine
CAS:<p>2'-13CCytidine is a cytidine nucleoside that inhibits the synthesis of RNA and DNA in cells. It is an analog of cytarabine, which is a pyrimidine nucleoside and an antineoplastic agent. 2'-13CCytidine has been shown to be effective as an antiviral agent against HIV-1 and HSV-2, as well as an immunosuppressant for the treatment of autoimmune diseases such as rheumatoid arthritis. This drug is used in chemotherapy to inhibit cell division in leukemia.</p>Formula:CC8H13N3O5Purezza:Min. 95%Peso molecolare:244.21 g/mol4-(Dimethoxymethyl)pyrimidine
CAS:<p>4-(Dimethoxymethyl)pyrimidine is a nitrogen heterocycle that is prepared by the reaction of formamide and nitrate. This compound has been shown to inhibit the replication of viruses such as HIV, herpes simplex virus type 2 (HSV-2), or vesicular stomatitis virus (VSV). 4-(Dimethoxymethyl)pyrimidine also binds to uracil in RNA, inhibiting RNA synthesis and leading to cell death. This compound can also be used as a precursor for the preparation of 2-aminopyrimidine, which is used in the synthesis of other compounds. 4-(Dimethoxymethyl)pyrimidine is used in organic synthesis for the preparation of benzene derivatives, such as nitrobenzene. This compound can also be synthesized by reacting formamide with toluene in an ultrasonic bath.</p>Formula:C7H10N2O2Purezza:Min. 95%Peso molecolare:154.17 g/mol5'-O-Acetyl-2',3'-dideoxyinosine
CAS:<p>5'-O-Acetyl-2',3'-dideoxyinosine is a nucleoside analogue that inhibits viral replication. It is a potent activator of the immune system and has been shown to be effective against cancer cells. 5'-O-Acetyl-2',3'-dideoxyinosine was originally synthesized as an antiviral agent, but it was found to be ineffective in this function. The drug binds to the ribonucleotide reductase enzyme, which converts ribonucleotides into deoxyribonucleotides and is essential for the production of DNA. The drug blocks the conversion of ribonucleotides into deoxyribonucleotides, preventing DNA synthesis and replication. This drug has also been shown to have anticancer activity by inhibiting DNA synthesis and cell division.</p>Formula:C12H14N4O4Purezza:Min. 95%Peso molecolare:278.26 g/molN2-Isobutyryl-2'-O-(2-methylacetamido)guanosine
<p>N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine is a modified nucleoside with antiviral, anticancer and antiretroviral activity. It is a novel monophosphate that has been shown to be effective against hepatitis B and HIV. N2-Isobutyryl-2'-O-(2-methylacetamido)guanosine inhibits the synthesis of viral DNA by acting as an activator of DNA polymerases.</p>Purezza:Min. 95%2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt
CAS:2'-Deoxy-5-hydroxymethylcytidine 5'-monophosphate sodium salt (2'-dO-5HmcMP) is a nucleoside analogue that inhibits the activity of reverse transcriptase, an enzyme required for replication of HIV. This compound is phosphorylated in vivo to 2'-dO-5HmcMP monophosphate, which then competitively inhibits the binding of dNTPs to the enzyme and prevents DNA synthesis. 2'-dO-5HmcMP also has anticancer activity and has been shown to inhibit the proliferation of cells in vitro. 2'-dO-5HmcMP has no significant toxicity to humans or other mammals.Purezza:Min. 95%1-(2-Deoxy- 2, 2- difluoro- b- D- xylofuranosyl)cytosine
CAS:<p>1-(2-Deoxy-2,2-difluoro-beta-D-xylofuranosyl)cytosine is a nucleoside (a compound consisting of a nucleotide base linked to a sugar). It is a modified form of cytosine that has been phosphorylated at the 2’ position. 1-(2-Deoxy-2,2-difluoro-beta-D-xylofuranosyl)cytosine has antiviral and anticancer activity through its ability to inhibit viral DNA synthesis and activate the immune system. This drug also has antitumor activity due to its ability to inhibit the tumor growth factor beta (TGFB). 1-(2-Deoxy-2,2-difluoro-beta-D -xylofuranosyl)cytosine can be used in cancer treatment as an anticancer agent.</p>Formula:C9H11F2N3O4Purezza:Min. 95%Peso molecolare:263.2 g/mol9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine
CAS:<p>9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine is a modified nucleoside that is used as an antiviral and anticancer agent. It acts as an activator for the synthesis of DNA, RNA, and protein. 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine also inhibits the growth of cancer cells by interfering with the division process. This drug is synthesized from 9-(5'-deoxy-5'-iodo-b-D-ribofuranosyl) -2,6 difluoro adenine (diFdA). The Ribonucleosides are then prepared in a similar manner to other nucleosides by using phosphoramidites. The product is then purified using HPLC.</p>Formula:C10H11F2N5O3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:287.23 g/mol2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt
CAS:<p>2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt (2'OMeEtGTP) is an antiviral agent that is used as a component of an antiviral drug. It inhibits the viral enzyme DNA polymerase, which prevents viral replication and transcription. This compound has been shown to have anticancer properties in vitro and in vivo in rat models. 2'OMeEtGTP is synthesized by reacting the nucleoside phosphoramidite 2'OMeEtGTP with triethylammonium phosphate (TEAP).</p>Purezza:Min. 95%2',3'-Dideoxy-N2-isobutyrylguanosine
<p>2',3'-Dideoxy-N2-isobutyrylguanosine is a monophosphate that inhibits viral replication by competing with the natural substrate, diphosphate. It is synthesized in high purity and quality by our company. 2',3'-Dideoxy-N2-isobutyrylguanosine has been used as an antiviral agent to inhibit the hepatitis B virus. This product is also of interest for its potential use in cancer treatment.</p>Formula:C14H19N5O4Purezza:Min. 95%Peso molecolare:321.34 g/mol8-Bromo-5'-o-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine
CAS:8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine (8-Bromo-5'-O-(DMT)-dG) is a novel nucleoside that is synthesized by reacting 8-bromo-5'-O-(dimethyoxytrityl)-2'-deoxyguanosine with dimethylaminomethylidene. It has antiviral, anticancer, and ribonucleoside activities. 8-Bromo-5'-O-(DMT)-dG is used as a building block for the synthesis of oligonucleotides, phosphoramidites, and other modified nucleosides. 8-Bromo-5'-O-(DMT)-dG is currently being developed as an anticancer drug.Formula:C34H35BrN6O6Purezza:Min. 95%Peso molecolare:703.6 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
CAS:<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used to synthesize oligonucleotides. It is a phosphoramidite, and can be used in the synthesis of DNA or RNA. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is an antiviral agent that has been shown to have anticancer activity in animal models. It has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) and serum enzymes, such as dismutase activity, in mice with lung cancer. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis.</p>Purezza:Min. 95%Thymidine-5'-diphosphate-6-deoxy-D-allose
<p>Thymidine-5'-diphosphate-6-deoxy-D-allose (TDP) is a high quality monophosphorylated nucleoside that is used as an activator, anticancer, and antiviral agent. TDP has been modified to improve the efficacy and safety of cancer treatments by enhancing the cytotoxicity of chemotherapeutics. TDP also has antiviral properties and can be used in the treatment of HIV infections by inhibiting viral replication.</p>Purezza:Min. 95%4'-Azidothymidine 5-triphosphate
CAS:4'-Azidothymidine 5-triphosphate (4AZTTP) is a deoxyribonucleoside that has been synthesized as an analog to thymidine. It has potent inhibitory activity against human immunodeficiency virus (HIV), and has been shown to be more effective than 2',3'-dideoxyinosine in inhibiting HIV replication. 4AZTTP inhibits the viral enzyme reverse transcriptase, which is crucial for the replication of HIV. This drug is activated by cellular enzymes and phosphorylated to 4'-azidothymidine 5'-triphosphate monophosphate, which can then bind to the viral DNA template and inhibit synthesis of RNA strands. The kinetic properties of 4AZTTP have been studied in detail using human lymphocytes as a model system for HIV infection.Formula:C10H16N5O14P3Purezza:Min. 95%Peso molecolare:523.18 g/mol3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine
CAS:3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine is a novel nucleoside analogue that has been synthesized to inhibit the activity of DNA polymerase. This compound is also an activator of diphosphate and ribonucleoside monophosphate. 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-2'-fluoroarabinocytidine has been shown to inhibit the replication of herpes simplex virus type 1 in cell culture and the replication of human cytomegalovirus in cell culture. 3',5'-Di-O-Benzoyl-N4-benzoyl-2'-deoxy-- 2'-fluoroarabinocytidine does not have any antiviral activity against HIV.Purezza:Min. 95%5'-O-DMT-2'-O-hexylamino-5-methyluridine
CAS:5'-O-DMT-2'-O-hexylamino-5-methyluridine is a nucleoside analog that is used in cancer treatment. It is synthesized by the chemical modification of uridine, which is converted to 5'-O-DMT-2'-O-hexylamino-5-methyluridine by reacting with 2',3'-dideoxyadenosine and 5,6,7,8,-tetrahydroisoquinoline. The monophosphate form of 5'-O-DMT-2'-O-hexylamino-5-methyluridine may be converted to the diphosphate form by phosphorylation with ATP. In addition to its anticancer effects, 5'-O-DMT-2'-O-hexylamino-5-methyluridine has antiviral and antiretroviral effects due to its inhibition of viral DNA synthesis.Formula:C37H45N3O8Purezza:Min. 95%Peso molecolare:659.79 g/mol9-(2-C-Methyl-b-D-ribofuranosyl)purine
CAS:<p>9-(2-C-Methyl-b-D-ribofuranosyl)purine is a nucleoside that is used as an activator in the synthesis of phosphoramidites. 9-(2-C-Methyl-b-D-ribofuranosyl)purine has antiviral and anticancer properties, and it also inhibits the growth of bacteria. This nucleoside is synthesized from 2,4,6-trichlorophenylisocyanate and 5'-O-(4,4'-dimethoxytrityl)-beta-D-ribofuranose. The chemical name for 9-(2-C methyl b D ribofuranosyl)purine is 690269 - 86 - 4.</p>Formula:C11H14N4O4Purezza:Min. 95%Peso molecolare:266.25 g/mol3',5'-Di-o-acetyl-O6-phenyl-2'-deoxyinosine
CAS:3',5'-Di-O-acetyl-O6-phenyl-2'-deoxyinosine is a nucleoside analog that has antiviral and anticancer activities. It is an activator of the enzyme ribonucleotide reductase and has been shown to be effective against herpes simplex virus type 1 and 2, cytomegalovirus, Epstein Barr virus, human immunodeficiency virus type 1, and Kaposi sarcoma cells. 3',5'-Di-O-acetyl-O6-phenyl-2'-deoxyinosine also inhibits the production of tumor necrosis factor alpha (TNFα), which can cause inflammatory reactions in the body. This compound is a modified nucleoside with high purity and quality. It has CAS number 133471-06-4.Formula:C20H20N4O6Purezza:Min. 95%Peso molecolare:412.4 g/molFluorescein alkynylamino-ATP - 1.0 mM solution
CAS:Fluorescein alkynylamino-ATP is a fluorescent nucleotide analog that is used in molecular biology for the detection of DNA. It is labeled with tetramethylrhodamine, which can be detected using a fluorescence microscope. Fluorescein alkynylamino-ATP is a postsynthetic modification to DNA, which means it is added after the DNA has been synthesized. This molecule can be incorporated into the growing strand by either monoaddition or polymerase extension. Fluorescein alkynylamino-ATP binds to the 3' end of a primer during polymerase chain reaction (PCR) and can be detected using electrophoresis and sequence analysis.Formula:C41H41N6O20P3Purezza:Min. 95%Peso molecolare:1,030.71 g/mol5,6-Dihydro-5'-O-DMT-thymidine 3'-CE phosphoramidite
This is a synthetic DNA analogue that is used in the synthesis of oligonucleotides. It is a phosphoramidite in which the 5,6-dihydro-5'-O-DMT group has been modified to allow for incorporation into DNA and RNA. This compound has antiviral and anticancer activities.Formula:C40H51N4O8PPurezza:Min. 95%Peso molecolare:746.83 g/mol3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine
3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine is a novel nucleoside analogue with high purity and quality. It is a DNA activator that has been shown to be active against both RNA and DNA viruses. 3'-Azido-N6-benzoyl-5'-O-benzoyl-2',3'-dideoxyadenosine phosphorylates to the corresponding monophosphate, which inhibits viral DNA synthesis by competitive inhibition of diphosphate formation. This compound has also been shown to be an effective inhibitor of HIV replication in vitro.Formula:C24H20N8O4Purezza:Min. 95%Peso molecolare:484.47 g/mol1-(3'-O-Nosyl-5'-O-trityl-2'-deoxy-b-D-lyxofuranosyl)thymine
CAS:Ribonucleosides are nucleosides that contain ribose as their pentose sugar. Ribonuclesides are synthetic, modified ribonucleosides that have been modified to include a 2'-deoxy-b-D-lyxofuranosyl group at the 3' position. Ribonuclesides activate antiviral activity by inhibiting viral DNA synthesis and protein synthesis. They also inhibit cancer cell proliferation by inhibiting DNA synthesis and RNA synthesis.Formula:C35H31N3O9SPurezza:Min. 95%Peso molecolare:669.7 g/mol2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate
<p>2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine-5'-triphosphate is a novel synthetic nucleoside analog with antiviral and anticancer properties. It is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine has been shown to be effective against human leukemia cells in vitro and in vivo.</p>Formula:C10H17ClN5O12P3Purezza:Min. 95%Peso molecolare:527.64 g/molN4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate
<p>N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate is a synthetic nucleoside that has antiviral activity. It is a modification of the natural nucleoside cytidine, where the 4th position of the ribose ring is substituted with an acetyl group and the 2' position of the sugar moiety is substituted with a 2' deoxyribofuranosyl group. N4-Acetyl-2'-deoxy-2'-fluoro-5'-O-DMT-cytidine 3'-O-succinate inhibits viral replication by inhibiting viral RNA synthesis. Its antiviral properties may be due to its ability to inhibit DNA polymerase and reverse transcriptase, which are enzymes that synthesize DNA from RNA.</p>Purezza:Min. 95%3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine
CAS:3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine is a novel antiviral agent that is synthesized as a deoxyribonucleoside monophosphate. It inhibits viral DNA polymerase and RNA synthesis by competitively inhibiting the incorporation of diphosphates into viral DNA. It has been shown to be active against herpes simplex virus type 1 and 2, vaccinia virus, influenza A virus, and Sindbis virus. 3',5'-Di-O-acetyl O6-benzyl-2'-deoxyguanosine has also been shown to have anticancer properties in vitro and in vivo.Formula:C21H23N5O6Purezza:Min. 95%Peso molecolare:441.44 g/mol8-Aminoadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:8-Aminoadenosine-5'-triphosphate sodium salt is a phosphoramidite that is used to synthesize antiviral nucleosides. It is a high quality product that can be used as an activator in the synthesis of ribonucleosides and deoxyribonucleosides. 8-Aminoadenosine-5'-triphosphate sodium salt has been shown to inhibit the growth of cancer cells.Formula:C10H17N6O13P3·xNaPurezza:Min. 95%Peso molecolare:522.2 g/mol4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidine-1-(b-D-ribofuranosyl-5'-triphosphate)
CAS:<p>4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidine-1-(b-D-ribofuranosyl-5'-triphosphate) is a nucleoside that inhibits the growth of cancer cells. It has been shown to inhibit the growth of leukemia and lymphoma cells in vitro. This compound is active against herpes simplex virus type 1 (HSV1) and has antiviral properties. The chemical synthesis of 4-amino-(1HNMPP) is novel and should provide high purity and quality products.</p>Formula:C21H24N5O13P3Purezza:Min. 95%Peso molecolare:647.36 g/mol2'-Deoxyxanthosine 5'-monophosphate
CAS:2'-Deoxyxanthosine 5'-monophosphate is a nucleoside which is an activator of the DNA polymerase. It has antiviral activity and is used in the synthesis of oligonucleotides. 2'-Deoxyxanthosine 5'-monophosphate is also used as a phosphoramidite in the chemical synthesis of DNA, and can be modified with fluorine or other atoms to form synthetic analogues.Purezza:Min. 95%Adenosine 5'-triphosphate trisodium salt
CAS:<p>ATP is an important molecule in the body that is involved in a number of cellular processes, including energy production and transmission. It has been shown to be tumorigenic and is found at high levels in plasma membranes and muscle cells. ATP binds to the adenylate cyclase enzyme in the cell membrane and stimulates its activity, which increases intracellular levels of cyclic AMP (cAMP). Cyclic AMP activates protein kinase A, which phosphorylates proteins, leading to a cascade of reactions that result in cellular changes. ATP also has pharmacological effects on the plasma membrane by increasing its permeability to certain ions such as potassium ions. This leads to an increase in the rate of depolarization of the cell membrane, which causes an influx of calcium ions into the cell.</p>Formula:C10H15N5O13P3Na3Purezza:Min. 95%Peso molecolare:575.14 g/mol3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine
CAS:<p>3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine is a nucleoside that is used in the antiviral drug Aciclovir. It is an analog of 2'-deoxyadenosine and inhibits viral DNA synthesis by acting as a chain terminator. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy a-5-fluorouridine has shown some anticancer activity against human tumor cells in culture, but its mechanism of action is not well understood.</p>Formula:C23H17Cl2FN2O7Purezza:Min. 95%Peso molecolare:523.29 g/molN6-Benzyladenosine 5'-triphosphate triethylammonium salt
CAS:N6-Benzyladenosine 5'-triphosphate triethylammonium salt is a hydrogen bond donor that is not naturally occurring. It has been shown to be a potent and selective analog of ATP with high specificity for cGMP-dependent protein kinase. This drug has been used to study the function of serotonin receptors, tyrosine kinases, and epidermal growth factor receptors. N6-Benzyladenosine 5'-triphosphate triethylammonium salt has also been shown to increase the sensitivity of cells to epidermal growth factor and to inhibit the reuptake of serotonin.END>Formula:C19H26N5O11P3·C18H48N3Purezza:Min. 95%Peso molecolare:899.95 g/mol3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is an inhibitor of the enzyme kinase. The active form of 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution inhibits human immunodeficiency virus (HIV) reverse transcriptase, preventing the synthesis of viral DNA. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution has been shown to inhibit cancer cell growth in culture and to inhibit cancer cell proliferation in mice. This compound is also active against cancer cells that are resistant to other anti-cancer drugs. 3'-Azido-3'-deoxythymidine-5'-triphosphate lithium salt - 100mM aqueous solution is phosphorylated by cellular kinases, which may beFormula:C10H16N5O13P3·xLiPurezza:Min. 95%Colore e forma:Colorless Clear LiquidPeso molecolare:507.18 g/mol3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine
3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is an antiviral agent that inhibits the production of virus particles by inhibiting DNA and RNA synthesis. It is a modified nucleoside analog that has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. This drug has also been shown to be effective against leukemia and lymphoma cells, as well as other types of cancer cells. 3'-O-Acetyl-5'-O-tert-butyldiphenylsilyl-2'-deoxy-2'-fluorothymidine is used for the treatment of AIDS, hepatitis B, hepatitis C, herpes zoster (shingles), and other diseases caused by viruses. It can be administered orally or intravenously.Formula:C28H33FN2O6SiPurezza:Min. 95%Peso molecolare:540.66 g/mol2'-O-(2-Ethoxy-2-oxoethyl)adenosine
<p>2'-O-(2-Ethoxy-2-oxoethyl)adenosine is a nucleoside that is a modified version of adenosine. It is phosphorylated to form 2'-O-(2-ethoxy-2-oxoethyl)adenosin-5'-yl monophosphate, which has antiviral activity and is used as an antiviral agent in the treatment of herpes simplex virus. The chemical structure of this nucleoside is novel, and it binds to the ribonucleotide reductase enzyme to prevent the synthesis of DNA and RNA. This drug also has anticancer properties, but it is not active against bacterial infections.</p>Purezza:Min. 95%2-Methylthioadenosine-5'-triphosphate
CAS:2-Methylthioadenosine-5'-triphosphate (2MeSATP) is a nucleotide analogue that inhibits the synthesis of ATP by binding to the adenylate cyclase enzyme. 2MeSATP has been shown to be a potent inhibitor of neuronal death and is used as a tool in cellular research. 2MeSATP binds to guanine nucleotide-binding protein (G protein), which inhibits its activity and prevents the activation of other downstream enzymes, such as phospholipase C, which are necessary for neurotransmitter release. 2MeSATP also has an inhibitory effect on several other enzymes, including phosphodiesterases and cyclases, in cellular models and whole cells.Formula:C11H18N5O13P3SPurezza:Min. 95%Peso molecolare:553.27 g/mol4'-Nitrobenzoyl-6-selenoinosine
CAS:4'-Nitrobenzoyl-6-selenoinosine is a monophosphate nucleoside that is synthesized by the phosphoramidite method. It has been shown to have antiviral and anticancer activities. The compound inhibits the synthesis of DNA and RNA, which may be due to its ability to inhibit the enzyme ribonucleotide reductase. 4'-Nitrobenzoyl-6-selenoinosine has also been shown to activate cellular transcription factors such as NF-κB and AP-1, resulting in increased expression of genes involved in apoptosis.Formula:C17H15N5O7SePurezza:Min. 95%Peso molecolare:480.29 g/mol5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine
<p>5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral drug that has been shown to inhibit the synthesis of viral RNA by inhibiting the activity of DNA polymerase. It is a novel antiviral drug with high purity and can be used for cancer treatment as well. 5'-O-tert-Butyldimethylsilyl-7-deaza-2'-deoxy-7-iodoadenosine also has a novel mechanism of action, which is different from other antiviral drugs such as ribonucleosides or deoxyribonucleosides. This compound is used in the synthesis of phosphoramidites for oligonucleotide synthesis.</p>Formula:C17H27IN4O3SiPurezza:Min. 95%Peso molecolare:490.41 g/molThymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt
CAS:Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt is a nucleoside that is a synthetic analog of thymidine. It has antiviral activity and is used in the synthesis of DNA and RNA. This product has shown to be effective against HIV, influenza, polio, herpes, and human papillomavirus. Thymidylyl-(3'-5')-2'-deoxyadenosine ammonium salt can also be used for the synthesis of phosphoramidites for oligonucleotide synthesis.Formula:C20H26N7O10P·NH3Purezza:Min. 95%Peso molecolare:572.47 g/mol2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt
CAS:<p>2',3'-Dideoxyinosine-5'-triphosphate triethylammonium salt (ddI-TP) is a nucleoside analog that inhibits HIV replication by competing with natural nucleosides for binding to HIV reverse transcriptase. ddI-TP acts as an inhibitor of human mitochondrial DNA polymerase γ, and blocks the synthesis of fatty acids in mouse cells. It is also able to inhibit signal pathways involving protein kinases and phosphatases. ddI-TP has been shown to be effective against hiv infection in mice. This drug can be used in the treatment of hiv infection, as well as in the prevention of its transmission from mother to child during pregnancy and breastfeeding.</p>Formula:C10H15N4O12P3Purezza:Min. 95%Peso molecolare:476.17 g/mol3'-Chloro-3'-deoxy-5'-O-tritylthymidine
CAS:3'-Chloro-3'-deoxy-5'-O-tritylthymidine (3CT) is an antiviral and anticancer drug that is a modified nucleoside. It is synthesized by reacting 3'-chloro-5'-O-tritylthymidine with trichloroacetonitrile. 3CT inhibits the synthesis of DNA and RNA, which may have antiviral and anticancer effects. It can be used to treat hepatitis B virus, herpes simplex virus, human papillomavirus, Epstein-Barr virus, and Kaposi's sarcoma. 3CT has been shown to be effective in treating cancer cells in culture by inhibiting DNA synthesis.Formula:C29H27ClN2O4Purezza:Min. 95%Peso molecolare:503 g/mol3-Deazaguanosine
CAS:<p>3-Deazaguanosine is a nucleotide that is found in uridine, which is present in the nucleic acids of all cells. It has been shown to be cytotoxic to colorectal adenocarcinoma and carcinoma cell lines, and this cytotoxicity may be due to its ability to inhibit energy metabolism. 3-Deazaguanosine has also been shown to significantly inhibit viral replication, including HIV and herpes simplex virus type 1. It binds with high affinity to monoclonal antibodies that are specific for nucleotide levels. 3-Deazaguanosine inhibits tissue culture enzyme activity and can cause significant changes in adenine nucleotide levels in cell culture.</p>Formula:C11H14N4O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:282.25 g/mol5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1)
CAS:<p>5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1) is a novel monophosphate nucleoside that has been synthesized and evaluated in vitro as an anticancer agent. It inhibits the proliferation of various human tumor cell lines, including breast cancer cells. This compound is also active against HIV-1 virus but not against other viruses tested. 5'- O- [Bis(4- methoxyphenyl) phenylmethyl] - thymidine 3'- (hydrogen phosphonate) ,compd. with N, N- diethylethanamine (1:1), like other nucleosides, can be modified to suit particular needs and then used for therapeutic purposes.</p>Formula:C31H33N2O9PPurezza:Min. 95%Peso molecolare:608.58 g/mol2'-Deoxy-2'-fluoroguanosine-5'-monophosphate
CAS:2'-Deoxy-2'-fluoroguanosine-5'-monophosphate is a phosphoramidite monoester with a diphosphate group that has been synthetically modified to provide antiviral and anticancer activity. It is an activator of DNA synthesis and inhibits the proliferation of tumor cells by interfering with DNA replication. The compound is also used as a precursor for the synthesis of 2'-deoxy-2'-fluoroguanosine, which has potent anti-HIV activity.Formula:C10H13FN5O7PPurezza:Min. 95%Peso molecolare:365.21 g/mol2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine
CAS:2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine is a monophosphate nucleoside analog that has antiviral activity against the Herpes virus. It is a cytosine analog that is incorporated into DNA and inhibits viral replication. 2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine has also been shown to have anticancer properties and high purity. This compound is synthesized by the reaction of 2'-deoxycytidine and 4-(2,2,2,-trimethylpropionyl)-1,3-butanediol with O-(7-azabenzotriazol-1-yl) N,N,N',N' tetramethyluronium hexafluorophosphate (HATU) in anhydrous pyridine. The CAS number for this compound is 10089862.Formula:C34H37N3O7Purezza:Min. 95%Peso molecolare:599.69 g/molXTT, sodium salt
CAS:<p>XTT is a tetrazolium compound that can be used to measure the activity of enzymes. It has been shown to inhibit the growth of tumor cells in vitro and in vivo. XTT can also be used as an antibacterial agent against C. glabrata and as an anthelmintic drug against tapeworms. This compound is not active against other bacteria, such as E. coli or S. aureus, because they are resistant to oxidative injury and have high levels of ABCG2 (ATP-binding cassette G2), which prevents intracellular accumulation of XTT.</p>Formula:C22H16N7NaO13S2Peso molecolare:673.53 g/molRef: 3D-X-5000
1gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta2500mgPrezzo su richiesta-Unit-ggPrezzo su richiesta2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine
CAS:2-Amino-6-chloro-9-(2-deoxy-3,5-di-O-benzoyl-2-fluoro-b-D-arabinofuranosyl)purine is a novel modified nucleoside with antiviral activity. It has been shown to inhibit the replication of the influenza A virus in cell culture and animal models. 2′Amino-6′chloro 9-(2′deoxy 3′,5′di O′benzoyl 2′fluoro b D arabinofuranosyl)purine is an analog of adenosine that has shown anticancer activity in vitro and in vivo. It inhibits DNA synthesis by inhibiting deoxyribonucleotide synthesis and ribonucleotide synthesis. This drug also inhibits cell proliferation and induces apoptosis.Formula:C24H19ClFN5O5Purezza:Min. 95%Peso molecolare:511.89 g/mol3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
CAS:<p>3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that is used in the synthesis of oligonucleotides. It is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to have high purity and quality. The synthesis of this compound involves the use of a novel activator, which is also available for purchase from this website. This nucleoside has been modified with tert-butyldimethylsilyl groups at the 3' and 5' positions of the ribose moiety, which prevents the hydrolysis of the phosphate ester bond by alkaline phosphatase enzymes, thus allowing for sequence determination.</p>Purezza:Min. 95%4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine
CAS:4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine is a novel nucleoside analogue that has high purity and high quality. It is an activator of DNA synthesis, diphosphate and monophosphate of deoxyribonucleosides, ribonucleosides and analogues. 4-Amino-1-(2',3',5'-tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine has been shown to have antiviral activities against herpes simplex virus type 1 (HSV1) in cell culture.Formula:C29H56N4O4Si3Purezza:Min. 95%Peso molecolare:609.04 g/mol1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione
CAS:<p>1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione is an organic semiconductor material. It is a dielectric with a high transition temperature and good electrical conductivity. This compound is a metal silicide with a low resistivity and high electron mobility. It can be used as an active layer in thin film transistors or as a field effect transistor channel material. 1,3-Dimethyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-pyrimidine-2,4,6-trione has been shown to have good chemical stability and thermal stability in air at temperatures up to 400°C.</p>Purezza:Min. 95%5-Bromo-5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite
5-Bromo-5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a novel, modified nucleoside and diphosphate that has antiviral activity. It is synthesized from 5-bromouracil and 2'-O-methyluridine by the use of a high purity reagent. The product is an anticancer agent that can be used to treat different types of cancer. This compound has also shown to have high purity and high quality.Formula:C40H48BrN4O9PPurezza:Min. 95%Peso molecolare:839.71 g/molAdenylosuccinic acid
CAS:<p>Adenylosuccinic acid is an organic acid that is synthesized through the deamination of adenosine monophosphate. It is used in transfection experiments to inhibit polymerase chain reaction (PCR) and reverse transcriptase. Adenylosuccinic acid inhibits DNA synthesis by targeting enzymes such as the ribonucleotide reductase and the DNA polymerase β-subunit. Adenylosuccinic acid also inhibits protein synthesis, which may be due to its ability to inhibit energy metabolism, leading to cellular death. This drug has been shown to have a wide range of pharmacological effects, including anti-inflammatory, analgesic, and antifungal activity.</p>Formula:C14H18N5O11PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:463.29 g/mol2'-TFA-NH-dC
CAS:<p>2'-TFA-NH-dC is a novel nucleoside analogue that has been modified to have antiviral and anticancer properties. The chemical structure of 2'-TFA-NH-dC closely resembles dC, which is a natural DNA nucleotide, but with the addition of an extra fluorine atom at the 2' position. This modification increases the potency of 2'-TFA-NH-dC by making it more difficult for enzymes in cells to break down the drug. The compound can be used as a monophosphate or diphosphate, and is synthesized from 2'-deoxyadenosine 5'-phosphoramidite and 1,2,4-triazole in water.</p>Formula:C11H13F3N4O5Purezza:Min. 95%Peso molecolare:338.24 g/molo-Methoxytopolin riboside
CAS:<p>o-Methoxytopolin Riboside is a novel phosphoramidite that can be used for the synthesis of ribonucleotides and deoxyribonucleosides. This product has antiviral and anticancer properties, as well as the ability to inhibit tumor growth by inducing apoptosis in cancer cells. It is synthesized from the natural compound o-methoxytyrosine by the addition of a phosphate group to the 3-position. The phosphate group is then modified to produce monophosphate or diphosphate forms. OMTPR has been shown to have anti-inflammatory properties and has been found to reduce inflammation in mice with colitis.</p>Formula:C18H21N5O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:387.39 g/mol2'-C-Methylinosine
CAS:<p>2'-C-Methylinosine is an analog of 2'-deoxyinosine that is used as a prodrug for the treatment of hepatitis B virus infection. It has been shown to inhibit RNA synthesis in cell cultures by competitively inhibiting the activity of rna-dependent RNA polymerase. This inhibition leads to the accumulation of unprocessed, inactive ribonucleotides, which are eventually degraded by cellular enzymes. 2'-C-Methylinosine is an analog of 2'-deoxyinosine that has been modified at the C2 position with methyl groups (hence its name). The modification increases the stability and solubility of this molecule. Clinical trials have shown that 2'-C-Methylinosine can be used to treat hepatitis B virus infection when combined with other drugs such as lamivudine or entecavir.</p>Formula:C11H14N4O5Purezza:Min. 95%Peso molecolare:282.25 g/mol6-Benzyloxypurine
CAS:<p>6-Benzyloxypurine is a fluorescent compound that can be used to measure the concentration of aqueous solutions. It is used in molecular modeling and as a tracer in bioassays. The binding constants for 6-benzyloxypurine have been determined by fluorescence spectrometry, and it has been shown to inhibit the growth of aerobacter aerogenes at concentrations greater than 0.5 mM. This inhibitor also has an inhibitory effect on the growth of tissue culture cells and wastewater treatment bacteria, such as enterococcus faecalis and pseudomonas aeruginosa. The optimum concentration of 6-benzyloxypurine to inhibit bacterial growth is 1 mM, which corresponds to a pH of ~8.2.</p>Formula:C12H10N4OPurezza:Min. 95%Peso molecolare:226.23 g/mol5'-O-DMT-N4-ethylcytidine
5'-O-DMT-N4-ethylcytidine is a novel nucleoside analogue. It has been used as a building block for the synthesis of modified oligonucleotides. 5'-O-DMT-N4-ethylcytidine is an antiviral agent that inhibits HIV replication by inhibiting reverse transcriptase, which is an enzyme that is necessary for the production of viral DNA from host cell RNA. The drug also has anticancer activity, which may be due to its ability to inhibit DNA synthesis and cellular proliferation.Formula:C32H35N3O7Purezza:Min. 95%Peso molecolare:573.64 g/mol2-Chloropyrimidine-4-carboxamide
CAS:<p>2-Chloropyrimidine-4-carboxamide is an activator that is a novel chemical entity of deoxyribonucleosides, phosphoramidites, ribonuclesides, and antiviral nucleosides. It has been shown to have high purity and quality. 2-Chloropyrimidine-4-carboxamide has been used in the synthesis of oligodeoxynucleotides for antiviral activity.</p>Formula:C5H4ClN3OPurezza:Min. 95%Peso molecolare:157.56 g/molTert-Butyl 2-Phenyl-4-(P-Tolylsulfonyloxy)-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate
CAS:Tert-Butyl 2-Phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is an antiviral agent that inhibits the replication of DNA and RNA. It is a phosphoramidate nucleoside analog and a novel compound that has been modified to improve its stability. Tert-butyl 2-phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is currently being investigated for use as a drug to treat HIV/AIDS. This compound has been shown to inhibit HIV protease by binding to the active site of the enzyme and preventing it from cutting the polypeptide chain into smaller pieces. Tert butyl 2 phenyl 4Formula:C25H27N3O5SPurezza:Min. 95%Peso molecolare:481.57 g/mol5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite
CAS:5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite is a high purity, novel, modified, antiviral and anticancer nucleotide. It is an analog of thymidine which has the methyl group at the 5' position replaced with a 5' amino group. This modification prevents conversion of the nucleoside to thymine and therefore inhibits DNA synthesis. The phosphoramidite is used as a building block for oligonucleotides in chemical synthesis. The phosphoramidite has shown antiviral activity against HIV by preventing reverse transcription of viral RNA into DNA. It also has been tested for its anticancer effects on human cells in vitro by inhibiting DNA synthesis and inducing apoptosis in cancer cells.Formula:C39H48N5O6PPurezza:Min. 95%Peso molecolare:713.8 g/mol2',3'-Dideoxy-2',3'-didehydroinosine
CAS:<p>2',3'-Dideoxy-2',3'-didehydroinosine is a synthetic pyrimidine compound that has been shown to inhibit tumor growth in animal models. It is used to prepare 2',3'-dideoxy-2',3'-didehydroinosine-5'-triphosphate, which inhibits the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase. This inhibition leads to cell death by inducing crosslinkers and inhibiting polymerase chain reaction. 2',3'-Dideoxy-2',3'-didehydroinosine can be synthesized from hydrochloric acid and carbonyl compounds such as glyoxal, acetaldehyde, or benzaldehyde.<br>2',3'-Dideoxy-2',3'-didehydroinosine is an important part of phylogenetic tree analysis because it provides information about evolutionary relationships between bacteria.</p>Formula:C10H10N4O3Purezza:Min. 95 Area-%Colore e forma:White PowderPeso molecolare:234.21 g/mol7-Deaza-2-mercaptohypoxanthine
CAS:<p>7-Deaza-2-mercaptohypoxanthine is a nucleoside that has been found to have anticancer activity in vivo. It has also been shown to inhibit the replication of HIV and herpes simplex virus. 7-Deaza-2-mercaptohypoxanthine is an analog of hypoxanthine, which is a nucleoside that can be found in DNA and RNA. In addition, this compound can be used as a phosphoramidite or nucleotide analogue for the synthesis of DNA and RNA. This compound can also be used as an antiviral agent against herpes simplex virus type 1 (HSV1).</p>Formula:C6H5N3OSPurezza:Min. 95%Peso molecolare:167.19 g/molCyclic diguanosine monophosphate
CAS:<p>Cyclic diguanosine monophosphate (c-di-GMP) is a nucleotide that is involved in bacterial cell signaling. It has been shown to be essential for the formation of bacterial biofilms and plays an important role in the development of infectious diseases. c-di-GMP is synthesized from guanosine triphosphate through a series of enzymatic reactions and then hydrolyzed by cyclic diguanosine monophosphatase, which leads to its termination as a second messenger. c-di-GMP interacts with proteins that regulate the expression of genes involved in biofilm formation, motility, and virulence. The synthesis and hydrolysis of c-di-GMP are regulated by multiple enzymes, including protein phosphatases, that control cellular physiology such as biofilm formation.</p>Formula:C20H24N10O14P2Purezza:Min. 95%Peso molecolare:690.41 g/mol7-Methylinosine
CAS:7-Methylinosine is a versatile compound that has various applications in different fields. It is used as an intermediate in the synthesis of drugs such as azasetron, eletriptan, and fructan. Additionally, it has been shown to have detergent properties that make it useful in cleaning products. 7-Methylinosine also plays a role in cholesterol metabolism and has been implicated in the development of fibrosis. Studies have found that this compound can inhibit the activity of enzymes involved in glucosinolate biosynthesis and may play a role in plant defense against pathogens. Furthermore, 7-Methylinosine has been isolated from Nocardia sp., which suggests its potential use as a source of novel bioactive compounds.Formula:C11H16N4O5Purezza:Min. 95%Peso molecolare:284.27 g/mol3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine
<p>3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is a novel nucleoside with antiviral and anticancer properties. It has been shown to inhibit the growth of human tumor cells in culture and induce apoptosis, as well as inhibit viral replication. 3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is an analogue of uridine, which can be used for the synthesis of DNA or RNA. The phosphate group is attached to the 3' carbon on the sugar moiety. This nucleoside has been modified from a natural ribonucleoside by substitution of a tertiary butylphenylsilyl group at the 2' position with an o-methyl group.<br>3'-O-tert-Butyldiphenylsilyl-2'-O-methyluridine is supplied as a white powder with purity greater than 99</p>Purezza:Min. 95%Adenosine 5'-diphosphate potassium salt
CAS:Adenosine 5'-diphosphate potassium salt can be used as a substrate for a variety of protein kinases known as AMP-activated protein kinases (AMPK)Formula:C10H14N5O10P2·KPurezza:Min. 95%Colore e forma:PowderPeso molecolare:465.29 g/mol2',3'-Di-O-methylguanosine
<p>2',3'-Di-O-methylguanosine is a nucleoside, which is a chemical compound composed of a nitrogenous base, a five-carbon sugar, and one phosphate group. It is an analog of guanosine that has been modified by replacing the 2' hydroxyl group with a methyl group. This modification prevents the phosphorylation of the monophosphate form to the diphosphate form. This modification also makes 2',3'-Di-O-methylguanosine an activator of DNA polymerase and RNA polymerase. The novel features of this compound make it an excellent candidate for anticancer and antiviral treatments.</p>Purezza:Min. 95%2-[2-(2-Naphthalenyl)ethoxy]adenosine
CAS:2-[2-(2-Naphthalenyl)ethoxy]adenosine is a structural determinant that belongs to the class of adenosine derivatives. It is an antagonist of adenosine receptors, binding to the A1 receptor with high affinity and blocking the effects of adenosine. 2-[2-(2-Naphthalenyl)ethoxy]adenosine has been shown to have a high affinity for benzyl and thioether groups in its structure, which are important for binding to the A1 receptor. This compound has been used in assays to determine the binding of other compounds with adenosine receptors. 2-[2-(2-Naphthalenyl)ethoxy]adenosine has also been shown as a radioligand for competitive binding studies with human brain membranes.Formula:C22H23N5O5Purezza:Min. 95%Peso molecolare:437.45 g/mol3'-O-DMT-thymidine
CAS:<p>3'-O-DMT-thymidine is a nucleoside analogue that is synthesized from thymidine. It has been shown to bind to the proviral dna of HIV and inhibit viral replication when present in a complex with the other nucleosides. 3'-O-DMT-thymidine is also stable at high temperatures and binds to carboxamide groups on proteins. This compound has been shown to be effective as a binder for surfaces and membranes, which may be due to its ability to form stable complexes with terminal phosphates. The stability of these complexes can be influenced by the presence of denaturants such as temperature, pH, or ionic strength parameters. 3'-O-DMT-thymidine also forms stable complexes with linkers that are sensitive to thermal denaturation.</p>Formula:C31H32N2O7Purezza:Min. 95%Peso molecolare:544.6 g/mol6-O-Benzyl-2'-deoxyguanosine
CAS:6-O-Benzyl-2'-deoxyguanosine is a synthetic nucleoside analog that inhibits the synthesis of DNA. It is used in animal studies as a pancreatic carcinogen, and has been shown to inhibit tumor growth in mice. This drug specifically binds to DNA at the O6 position of guanine and methylates the adjacent cytosine residue, thereby preventing synthesis of DNA. 6-O-Benzyl-2'-deoxyguanosine also inhibits the activity of an enzyme called methyltransferase, which converts S-adenosylmethionine into S-adenosylhomocysteine, an intermediate in one of the pathways that produce methionine from homocysteine. This inhibition leads to an accumulation of methionine and its metabolites, including homocysteine and cystathione beta synthase, which can cause cell death.Formula:C17H19N5O4Purezza:Min. 95%Peso molecolare:357.36 g/molN4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite
CAS:<p>N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite is a novel nucleoside. It is a monophosphate and cytidine analog that has been shown to be effective in the treatment of cancer. N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite also inhibits viral replication by preventing the synthesis of DNA and RNA. This drug can be used as an activator for synthesis of modified oligonucleotides.</p>Formula:C41H50N5O8PPurezza:Min. 95%Peso molecolare:771.84 g/molN6,5'-O-Dibenzoyl-2'-deoxy-adenosine
<p>N6,5'-O-Dibenzoyl-2'-deoxy-adenosine is a monophosphate nucleoside that is used in the synthesis of DNA. It is synthesized from 2'-deoxyadenosine, which is an antiviral agent against influenza virus and anticancer agent. N6,5'-O-Dibenzoyl-2'-deoxy-adenosine has been shown to be a potent activator of the polymerase chain reaction with high purity and novel properties.</p>Formula:C24H21N5O5Purezza:Min. 95%Peso molecolare:475.45 g/molL-Ribose NAD
<p>L-Ribose NAD is a nucleoside that belongs to the group of ribonucleosides. It is a novel modified monophosphate and diphosphate nucleotide. L-Ribose NAD has antiviral, anticancer, and immunomodulatory activities. L-Ribose NAD can activate cells with DNA damage by inhibiting the synthesis of deoxyribonucleosides, which are needed for DNA repair. This product has a high purity level and high quality.</p>Purezza:Min. 95%Peso molecolare:663 g/molN2-DMF-2'-O-methylguanosine
CAS:<p>N2-DMF-2'-O-methylguanosine is a nucleoside that is used as an antiviral agent and anticancer drug. It has been shown to inhibit the growth of human cancer cells in vitro and in vivo. N2-DMF-2'-O-methylguanosine has also been shown to inhibit viral replication by inhibiting DNA synthesis. This nucleoside is a novel compound that can be synthesized using phosphoramidites, which are high quality and yield high purity products.</p>Formula:C14H20N6O5Purezza:Min. 95%Peso molecolare:352.35 g/mol2'-Deoxyadenosine-5'-carboxylic acid
CAS:dA oxidised at the 5'-position.Formula:C10H11N5O4Purezza:Min. 95%Peso molecolare:265.23 g/mol5'-O-DMT-2'-O-hexylaminoadenosine
<p>5'-O-DMT-2'-O-hexylaminoadenosine is a modified nucleoside that has antiviral activity. It is the monophosphate form of 5'-O-DMT-2'-O-hexylaminoadenosine, and it is used in the synthesis of phosphoramidites for DNA and RNA. This nucleoside is also an activator for novel antiviral drugs.</p>Formula:C37H44N6O6Purezza:Min. 95%Peso molecolare:668.8 g/mol5-[(Methylamino)methyl]uridine
CAS:<p>5-[(Methylamino)methyl]uridine is a proton-containing analog of uridine. It is an epigenetic modifier that has been shown to have conformational properties that are similar to those of uridine. 5-[(Methylamino)methyl]uridine has been shown to modify the glycosidic bond and ring structures, which are important for its function in protein synthesis. The compound can also be found as a chemical structure in the ribosomal subunit, where it is involved in protein synthesis and translation. 5-[(Methylamino)methyl]uridine has shown potential as a therapeutic agent for cancer treatment due to its ability to inhibit the expression of oncogenes in cells and induce programmed cell death (apoptosis).</p>Formula:C11H17N3O6Purezza:Min. 95%Peso molecolare:287.27 g/mol2-Amino-4-methoxypyrimidine
CAS:<p>2-Amino-4-methoxypyrimidine is an organic compound that can be synthesized from 2-amino-4-chloropyrimidine. It is a colorless, water soluble solid with a melting point of 166°C. The UV spectrum of 2-amino-4-methoxypyrimidine exhibits absorption maxima at 240 nm and 280 nm. When 2-amino-4-methoxypyrimidine is exposed to UV light, it emits fluorescent light at 360 nm. The IR spectrum exhibits absorption bands at 3200 cm−1, 1650 cm−1, and 1530 cm−1. Hydrogen bonding interactions occur between the methoxy group and the protonated amine group in the molecule's structure. The yield of this reaction was found to be 65% by GC analysis. This reaction occurs in two steps: first, the imino group reacts with n hexane to form an iminium ion</p>Purezza:Min. 95%2'-Deoxy-5'-O-DMT-adenosine
CAS:<p>2'-Deoxy-5'-O-DMT-adenosine is a nucleoside that is structurally related to adenosine. It is synthesized by the phosphoramidite approach and can be used as an activator for RNA synthesis. 2'-Deoxy-5'-O-DMT-adenosine has shown anticancer activity in vitro and in vivo, which may be due to its ability to inhibit RNA synthesis and DNA replication.</p>Formula:C31H31N5O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:553.61 g/mol[1',2',3',4',5'-13C5]-4-Thiothymidine
<p>[1',2',3',4',5'-13C5]-4-Thiothymidine is an antiviral, anticancer, and activator of DNA synthesis. It is a monophosphate analog of thymidine that has been modified to include a radioactive isotope. [1',2',3',4',5'-13C5]-4-Thiothymidine binds to the active site of the enzyme ribonucleotide reductase which is responsible for the production of DNA from RNA. The incorporation of this radioactively labeled analog into DNA prevents its degradation by nucleases and allows for the detection and quantification of DNA synthesis via autoradiography.</p>Purezza:Min. 95%2'-Deoxy-1,N6-dimethyladenosine
<p>2'-Deoxy-1,N6-dimethyladenosine is a nucleoside that is used for the synthesis of DNA and RNA. It has antiviral activity against HIV and herpes simplex virus type 1 (HSV-1). 2'-Deoxy-1,N6-dimethyladenosine binds to viral DNA and inhibits viral replication by preventing the viral DNA from being replicated. It also inhibits the synthesis of viral proteins. This nucleoside is synthesized in a high purity and quality, which makes it an excellent starting material for use in the synthesis of other nucleosides or phosphoramidites.</p>Purezza:Min. 95%N1-Methyladenosine hydroiodide
CAS:<p>N1-Methyladenosine hydroiodide is a novel nucleoside analogue that inhibits viral replication by preventing the formation of viral DNA. It also inhibits the growth of cancer cells and is used as an anticancer drug. N1-Methyladenosine hydroiodide has been shown to be an activator of RNA polymerase II, increasing the production of messenger RNA (mRNA) in human cells. The phosphoramidite form of this compound is used for the synthesis of oligodeoxyribonucleotides, which are chemically modified in order to improve their stability and inhibit degradation by nucleases. N1-Methyladenosine hydroiodide is highly pure and has CAS No. 34308-25-3.</p>Formula:C11H15N5O4·HIPurezza:Min. 95%Peso molecolare:409.18 g/mol4-Methyl-6-phenyl-pyrimidine-2-thiol
CAS:4-Methyl-6-phenyl-pyrimidine-2-thiol is a copper(II) dehalogenating agent that belongs to the group of amplifiers. It has been used in the preparation of syntheses, including as an intermediate in the synthesis of phenylpyrimidines and amidines. The synthesis of 4-methyl-6-phenyl-pyrimidine-2-thiol can be accomplished by condensation of phleomycin with a biaryl. This reaction is followed by oxidation to give a biaryl sulfone, which is then reduced with hydrogen gas and ammonium formate.Formula:C11H10N2SPurezza:Min. 95%Peso molecolare:202.28 g/molAFB-guanine
CAS:<p>AFB-guanine is a purine nucleoside that has been found to be an intermediate in the conversion of adenosine to inosine. The toxicity of AFB-guanine was studied using the model system of rat liver microsomes and human liver. It was observed that AFB-guanine is metabolized by glycosylases, which act on purines and pyrimidines. The glycosylase activity was inhibited by dicoumarol, which results in a decrease in the amount of AFB-guanine that is converted to adenosine triphosphate (ATP). The study also showed that histological analysis revealed degenerative diseases and cancer in mice fed with AFB-guanine, suggesting that this compound may be carcinogenic.</p>Formula:C22H17N5O8Purezza:Min. 95%Peso molecolare:479.4 g/mol5-Methylcytidine HCl
<p>5-Methylcytidine HCl is a novel antiviral and anticancer agent. It possesses two important properties: it is an activator of the enzyme ribonucleotide reductase, which regulates DNA synthesis and repair; and it inhibits the activity of DNA polymerases. It is also chemically modified to allow its use in phosphoramidite synthesis. 5-Methylcytidine HCl has been shown to cause apoptosis in cancer cells, as well as inhibit the growth of bacteria.</p>Formula:C10H15N3O5·HClPurezza:Min. 95%Peso molecolare:293.7 g/mol2-[2-(4-Fluorophenyl)ethoxy]adenosine
CAS:<p>2-[2-(4-Fluorophenyl)ethoxy]adenosine is a hydrogen-bonded, hydrated, switchable molecule. The techniques used to characterize this compound include vibrational spectroscopy and Raman spectroscopy. 2-[2-(4-Fluorophenyl)ethoxy]adenosine has been shown to have high salt and thermal stability. It has also been shown to undergo conformational changes in the presence of chemists.</p>Formula:C18H20FN5O5Purezza:Min. 95%Peso molecolare:405.38 g/mol2'-O-(tert-Butyldimethylsilyl)-3'-deoxy-5'-O-trityluridine
CAS:2'-O-(tert-Butyldimethylsilyl)-3'-deoxy-5'-O-trityluridine is a nucleoside that has antiviral and anticancer properties. It is a monophosphate of uridine, which is an important precursor in the synthesis of DNA and RNA. This product has been modified to improve its purity and quality, making it suitable for use in laboratory research.Formula:C34H40N2O5SiPurezza:Min. 95%Peso molecolare:584.78 g/mol2,5'-Anhydro-thymidine
CAS:2,5'-Anhydro-thymidine is an analog of thymidine that is used in the diagnosis of women with suspected acute ischemic brain damage. It is a colony-stimulating factor that can be activated by the presence of inflammatory bowel disease or bowel disease. 2,5'-Anhydro-thymidine has been shown to cause ventricular dysfunction and to increase levels of brain natriuretic peptide in mice undergoing rotarod tests. The use of this compound has been shown to improve outcomes in animal models of acute ischemic brain damage and cancer.Formula:C10H12N2O4Purezza:Min. 95%Peso molecolare:224.21 g/molO6-Benzyl guanosine
CAS:<p>O6-Benzyl guanosine is a polymerized compound that has been shown to have anticancer efficacy. It has been tested in mice with medulloblastoma, a type of brain tumor, and in rats with breast cancer. O6-Benzyl guanosine was found to be hydrophobic and bound to the methyltransferase enzyme, which resulted in the inhibition of DNA synthesis. The polymerized compound is able to form conjugates with other molecules such as iron oxide nanoparticles or hydrazone derivatives, which can be used for treatments that involve bioconjugate chemistry.</p>Formula:C17H19N5O5Purezza:Min. 95%Peso molecolare:373.36 g/mol7’-OH-N-trityl morpholino uracil
CAS:<p>Please enquire for more information about 7’-OH-N-trityl morpholino uracil including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C28H27N3O4Peso molecolare:469.53 g/mol5-Chloro-2',3'-O-isopropylidenecytidine
<p>5-Chloro-2',3'-O-isopropylidenecytidine is a synthetic nucleoside that is activated by phosphorylation to form the corresponding nucleotide. It has antiviral and anticancer properties, and can be used as a building block for synthesis of other nucleosides. 5-Chloro-2',3'-O-isopropylidenecytidine is synthesized from 2,4-dichlorophenoxyacetic acid (DCA) and 2,5-dichloroaniline in the presence of sodium cyanide. The compound was first synthesized in 1972 and its chemical structure was determined in 1974. 5-Chloro-2',3'-O-isopropylidenecytidine has been shown to inhibit DNA synthesis by binding to viral diphosphate and deoxyribonucleosides. This compound also inhibits the activity of bacterial DNA gyrase and DNA top</p>Formula:C12H16ClN3O5Purezza:Min. 95%Peso molecolare:317.73 g/mol2-Fluoroinosine
CAS:<p>2-Fluoroinosine is a chemical that inhibits protein synthesis by blocking the attachment of amino acids to their corresponding tRNA molecules. This drug is used in the treatment of cancer, as it inhibits cell growth and prevents tumor cells from dividing. 2-Fluoroinosine has been shown to be effective against human leukaemia cells, with its inhibitory properties being due to its ability to dephosphorylate the enzyme RNA polymerase II. This drug also has anti-malarial properties and can be used for the treatment of Chagas disease. 2-Fluoroinosine is synthesized from xanthosine, which is an intermediate in purine metabolism and can be obtained from naturally occurring sources or chemically through a solid phase synthesis.<br>2-Fluoroinosine is activated by UV light and can be synthesized using single stranded DNA or synthetases such as those found in calf thymus tissue. The catalytic mechanism of this drug has</p>Formula:C10H11FN4O5Purezza:Min. 95%Peso molecolare:286.22 g/mol5'-Amino-2',5'-dideoxyuridine
CAS:5'-Amino-2',5'-dideoxyuridine (5-ADU) is a pyrimidine nucleoside that is structurally similar to thymidylate, which it inhibits. 5-ADU is used in the treatment of viral infections and cancers, as well as in the prevention of radiation injury. It has been shown to be an effective antiviral agent against herpes virus and some DNA viruses, such as adenovirus, vaccinia virus, and poliovirus. 5-ADU also enhances the effects of azauridine and other pyrimidine nucleosides in bacterial enzymes such as E. coli. 5-ADU has not been shown to be active against uninfected cells or tissues.Formula:C9H13N3O4Purezza:Min. 95%Peso molecolare:227.22 g/mol2-Methanesulfonyl-pyrimidine
CAS:2-Methanesulfonyl-pyrimidine is a thiourea that is used as a catalyst in organic synthesis. It can be prepared by reacting phosphorus oxychloride with malonate and hydrochloric acid at temperatures of about 0°C to 150°C. The chloride anion is replaced by the sulfonyl chloride, which has high affinity for the 2-position of thiourea. This reaction leads to an intermediate that can be hydrolyzed with hydrochloric acid to produce 2-methanesulfonyl-pyrimidine. 2-Methanesulfonyl-pyrimidine is soluble in water and can be used as a catalyst in wastewater treatment processes, such as cyclic oxidation or oxychlorination reactions.Purezza:Min. 95%N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite
CAS:N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite is an antiviral agent that inhibits the activity of viral DNA polymerase. This chemical has been shown to be effective against herpes virus, pox virus and HIV. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE phosphoramidite is a novel nucleotide analogue that contains a modified deoxyribose sugar backbone. It has been shown to be active against cancer cells in vitro, but not in vivo.Formula:C47H51FN7O7PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:875.95 g/mol8-Aza-2'-deoxyadenosine
<p>8-Aza-2'-deoxyadenosine is an anion that is cytotoxic to cells and can be activated to form a phosphate ester. It has been shown to have a higher cytotoxicity than adenosine in cell cultures, but is less effective in animal studies. 8-Aza-2'-deoxyadenosine has been shown to have a significant toxicity in rats and mice when administered at doses greater than 500 mg/kg body weight. The activation of 8-aza-2'-deoxyadenosine into the phosphate ester can be stereoselective. This activation has also been shown to cause enhancement of tumor growth inhibition.</p>Purezza:Min. 95%2,6-Diamino-9-(3'-amino-2',3'-dideoxy-β-D-ribofuranosyl)purine
CAS:<p>2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is an antiviral agent that inhibits the replication of the viral DNA by binding to the viral DNA and preventing its transcription into RNA. It has been shown to be active against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). 2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is a modified nucleoside that can be used in various areas of research, including antiviral and anticancer activities.</p>Formula:C10H15N7O2Purezza:Min. 95%Peso molecolare:265.28 g/mol5’-O-DMT cET-N2-isopropylguanosine 3’-OCE amidite
CAS:<p>Please enquire for more information about 5'-ODMT cEt G Phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C46H56N7O9PPeso molecolare:881.95 g/molN6-Aminoadenosine
CAS:<p>N6-Aminoadenosine is a purine nucleoside that is involved in the synthesis of adenosine. It can be found in a number of tissues and has been shown to have an agonist potency similar to 2-phenylaminoadenosine, but with a longer duration of action. N6-Aminoadenosine is also present as one of two stereoisomers, the other being N2-aminoadenosine. These two aminosides are hydrolyzed by triazol and sinoatrial enzymes. The affinity of N6-aminoadenosine for cellular receptors has been shown using high affinity assays on rat heart cells.</p>Purezza:Min. 95%N6-(6-Aminohexyl)-2'-deoxyadenosine
CAS:<p>N6-(6-Aminohexyl)-2'-deoxyadenosine is a novel nucleoside that is structurally related to the natural nucleosides, dATP and dGTP. It has been shown to be an activator of ribonucleosides and phosphoramidites, which are used in the synthesis of DNA and RNA. N6-(6-Aminohexyl)-2'-deoxyadenosine has also been shown to inhibit cancer cells as well as antiviral activity against HIV-1.</p>Formula:C16H26N6O3Purezza:Min. 95%Colore e forma:Slightly Yellow PowderPeso molecolare:350.43 g/mol2'-Deoxy-N2-methylguanosine
CAS:<p>2'-Deoxy-N2-methylguanosine is a nucleoside with anticancer properties. It is a phosphoramidite, which is an analog of the natural nucleotide guanosine, where the 2'-hydroxyl group has been replaced by a methylene group. This compound is used in DNA synthesis and RNA synthesis. It can be used as a monophosphate or diphosphate. It also has antiviral and anti-inflammatory activities, as well as N2-methylamino moiety that can be used for the treatment of cancer and inflammatory diseases such as arthritis.</p>Formula:C11H15N5O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:281.27 g/molThymidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:<p>Thymidine-5'-triphosphate sodium salt is a modified nucleoside with anticancer properties. It is a high-quality, high-purity ribonucleoside that can be used as an activator for the synthesis of deoxyribonucleosides and phosphoramidites. Thymidine-5'-triphosphate sodium salt has antiviral activity, which is due to its ability to inhibit viral DNA replication and transcription. This compound also has the potential to be used in the treatment of cancer cells by inhibiting DNA synthesis and cell division.</p>Formula:C10H17N2O14P3·xNaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:482.17 g/molN2-Benzoylguanosine
CAS:<p>N2-Benzoylguanosine is a nucleotide derivative that is formed by the acetylation of guanosine. It has been shown to act as a buffer in alkaline solutions and isomerizes to its n-oxide form when heated. N2-Benzoylguanosine reacts with peroxides such as hydrogen peroxide, glyoxal, and organic peroxides, forming hydroperoxide intermediates that can be converted into other products. The acidic hydrolysis of N2-benzoylguanosine yields the corresponding 6-benzoyladenosines. It has been shown to enhance the activity of uridine in inhibiting bacterial growth, while also acting as an inhibitor of viral RNA synthesis. This compound also reacts with nitrous acid to form an n6-benzoyladenosine derivative that inhibits the formation of RNA chains during transcription.</p>Formula:C17H17N5O6Purezza:Min. 95%Colore e forma:White to beige solid.Peso molecolare:387.35 g/mol3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin
CAS:<p>3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin is a nucleoside analog that is used as an activator of phosphoramidite. It can be used as a building block in the synthesis of modified phosphoramidites and it has antiviral, anticancer, and antiinflammatory properties. 3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin is a novel nucleoside analog that can be used to synthesize DNA or RNA. It is also an inhibitor of deoxyribonucleoside kinase, preventing the conversion of deoxyribonucleosides into diphosphate monophosphates.</p>Formula:C12H15N5O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:309.28 g/molN6-Dibenzoyl-3-deaza-2'-deoxy-5'-O-DMT-3-methyladenosine 3'-CE phosphoramidite
CAS:N6-Benzoyl-3-deaza-2'-deoxy-5'-O-DMT-3-methyladenosine 3' is a nucleoside that has been modified to be resistant to the enzymatic degradation by ribonucleases. The phosphoramidite is used in the synthesis of DNA and can be used as an antiviral or anticancer drug. It also acts as a competitive inhibitor of adenosine deaminase, which is an enzyme involved in the metabolism of purines. N6-Benzoyl-3-deaza-2'-deoxy-5'-O-DMT-3 methyladenosine 3' can inhibit viral replication by inhibiting RNA polymerase activity, and it has been shown to have antifungal properties.Formula:C56H59N6O8PPurezza:Min. 95%Peso molecolare:870.99 g/mol5'-o-DMT-N4-benzoyl-5-methyl-2'-o-methylcytidine 3'-ce phosphoramidite
CAS:<p>5'-O-DMT-N4-benzoyl-5-methyl-2'-O-methylcytidine 3'-ce phosphoramidite is a high purity, diphosphate, CAS No. 166593-57-3, Modified, Anticancer, DNA. It is a novel activator monophosphate that can be used for the synthesis of phosphoramidites for oligonucleotide synthesis and as a novel building block for nucleosides and deoxyribonucleosides. 5'-O-DMT-N4-benzoyl-5-methyl-2'-O-methylcytidine 3'-ce phosphoramidite has been shown to have anticancer activity in vitro. The cytotoxic effect of this compound is mediated by its ability to inhibit DNA replication and induce apoptosis in human leukemia cells.</p>Formula:C48H56N5O9PPurezza:Min. 95%Peso molecolare:878.00 g/mol5′-O-DMT-LNA N-Bz 5-Me cytidine
CAS:<p>5′-O-DMT-LNA N-Bz 5-Me cytidine is a protected LNA cytidine nucleoside.</p>Formula:C39H37N3O8Purezza:Min. 95%Peso molecolare:675.73 g/molLamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution
Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution is an antiviral drug used to treat HIV/AIDS and hepatitis B infections. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, acting by blocking the viral enzyme reverse transcriptase. Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution also inhibits cellular viral DNA synthesis and has been shown to exhibit anticancer activity in vitro and in vivo. This product is synthesized from raw materials through a novel process that involves modification of the phosphoramidite monophosphate with tetratriethylammonium salts.Formula:C32H74N7O12P3SPurezza:Min. 95%Peso molecolare:873.96 g/molm-Methoxytopolin riboside
CAS:m-Methoxytopolin riboside is a nucleoside that is a phosphoramidite derivative of the natural nucleoside, topolin riboside. This compound has antiviral and anticancer activities. It inhibits viral DNA synthesis and also induces apoptosis in cancer cells. m-Methoxytopolin riboside is modified with a methoxy group at the 3' position of the sugar moiety. This modification prevents incorporation into DNA and RNA, thereby inhibiting viral replication and inducing apoptosis in cancer cells.Formula:C18H21N5O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:387.39 g/mol[(2S,6R)-6-{N6-Benzoyladenin-9-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:<p>Nucleotide analogue for use in oligonucleotide synthesis</p>Formula:C38H37ClN7O4PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:722.17 g/mol6-Methyluridine
CAS:<p>Methyluridine is a derivative of uridine that is used in the synthesis of pyrimidine nucleotides. This drug is also an inhibitor of orotidine 5′-monophosphate decarboxylase, which converts orotic acid to uracil. The conformational properties of methyluridine have been studied and found to be similar to those of other purine derivatives, such as adenine and guanine. In addition, methyluridine has been shown to inhibit the growth of typhimurium and increase the production of uracil in human lymphocytes. Methyluridine is metabolized by hydroxylation in liver microsomes, yielding 6-carboxylic acid.</p>Formula:C10H14N2O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:258.23 g/mol1-b-D-Arabinofuranosyluracil 5'-monophosphate
CAS:1-b-D-Arabinofuranosyluracil 5'-monophosphate is a pyrimidine nucleotide analog. Because of its structural similarity to natural nucleotides, it can interact with enzymes involved in nucleic acid synthesis. It is also a metabolite of Ara-U (arabinosyluracil), which is itself a compound studied for its biological activity. Scientists could potentially use this molecule in research to study how cells process and use nucleotides, and to understand how changes in nucleotide structure can affect biological processes.Formula:C9H13N2O9PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:324.18 g/mol4-Chloro-5-iodo-pyrrolo[2,3-d]pyriMidine-7-carboxylic acid tert-butyl ester
CAS:Focuses is a chemical compound that does not have any known commercial or industrial uses.Purezza:Min. 95%2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine
CAS:2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine is an analog of the nucleoside uridine. It is a potent inhibitor of protein synthesis in cells, and has the potential to be used as a long-term treatment for tuberculosis. 2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in mice with influenza or hepatitis, and also inhibits the replication of HIV. This drug may also have antibacterial properties due to its ability to inhibit bacterial DNA gyrase and topoisomerase IV. 2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine binds to an antigen on the surface of cells, activating them.Formula:C20H26N7O10PSPurezza:Min. 95%Peso molecolare:587.5 g/molN2-Acetyl-5'-O-DMT-guanosine
CAS:<p>N2-Acetyl-5'-O-DMT-guanosine is a novel anticancer nucleoside that has been synthesized to mimic the natural nucleotides found in DNA. It is phosphorylated to N2-acetyl-5'-O-DMT-guanosine monophosphate, which can be converted back to the active form of N2-acetyl-5'-O-DMT guanosine by phosphatases. This agent activates DNA synthesis and inhibits viral replication, including HIV and herpes simplex virus. The antiviral activity is due to its inhibition of viral DNA polymerase and diphosphate kinase.</p>Purezza:Min. 95%Guanosine 5'-diphosphate sodium
CAS:<p>Pyruvate kinase substrate</p>Formula:C10H15N5O11P2•Na2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:466.19 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-8-oxoadenosine 3'-CE phosphoramidite
CAS:N6-Benzoyl-2'-deoxy-5'-O-DMT-8-oxoadenosine 3'-CE phosphoramidite is an 8-oxo modified amiditeFormula:C47H52N7O8PPurezza:Min. 95%Peso molecolare:873.95 g/mol5’-O-DMT-2’-O,4’-C-methylene-5-methyluridine
CAS:<p>5’-O-DMT-2’-O,4’-C-methylene-5-methyluridine is a nucleoside that is used as an antiviral and anticancer agent. It is a novel compound that has not been previously described in the literature. 5’-O-DMT-2’-O,4’-C methylene 5 methyluridine has been shown to inhibit the replication of the herpes virus in vitro (in cell culture) and in vivo (in animals). This compound also inhibits the proliferation of cancer cells by inhibiting DNA synthesis. It may be used as an anticancer agent or an antiviral agent.</p>Purezza:Min. 95%2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite
CAS:2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite is a novel nucleoside analog that inhibits viral DNA replication and has antiviral properties. It is an effective inhibitor of HIV, HSV, and HCV. The drug works by binding to the viral DNA polymerase enzyme, thereby blocking the RNA-dependent DNA polymerase activity and inhibiting viral DNA synthesis. 2'-Fluoro-5'-o-DMT-2'-deoxyinosine-3'-ce-phosphoramidite is a modified nucleoside with a fluorine atom at the 5' position of the sugar moiety, which prevents phosphodiester cleavage by phosphodiesterases in the cell's cytoplasm. This drug also has anticancer effects on human cancer cells by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase.Formula:C40H46FN6O7PPurezza:Min. 95%Peso molecolare:772.8 g/mol2'-Deoxy-4'-ethynyl-2-fluoroadenosine
CAS:<p>2'-Deoxy-4'-ethynyl-2-fluoroadenosine (EFdA) is an analog of adenosine. EFdA is a potent inhibitor of HIV replication, and has been shown to be effective against other viruses such as influenza virus, herpes simplex virus, and vesicular stomatitis virus. EFdA was the first nucleoside analog to show antiviral activity in tissue culture against these viruses. This drug also inhibits the synthesis of mitochondrial rRNA and reduces the formation of mitochondrial DNA in human cells by inhibiting mitochondrial DNA polymerase γ. EFdA also prevents the binding of monoclonal antibodies to human B lymphocytes, which may be due to its steric interactions with plasma RNA. This drug is metabolized by cytochrome P450 2C8 and 2C9 into a variety of metabolites that are excreted in urine as glucuronides or sulfates. EFdA has a long</p>Formula:C12H12FN5O3Purezza:Min. 95%Peso molecolare:293.25 g/mol5'-Biotin phosphoramidite
CAS:<p>Biotin phosphoramidite is a biotin-containing compound that is used as an extracellular probe for bacterial cells. It can be used to permeabilize cells, and it has been shown to have cytosolic uptake in various cell types. Biotin phosphoramidite binds to peptidoglycan in the cytosol of bacterial cells, and this binding induces internalization. This compound also has the ability to bind to peptidoglycan in the cytosol of eukaryotic cells, but does not induce internalization. Experiments with vibrio parahaemolyticus suggest that biotin phosphoramidite is a marginally effective inhibitor of this organism's uptake of unmodified peptidoglycan.</p>Formula:C46H64N5O6PSPurezza:Min. 95%Peso molecolare:846.07 g/mol7-deaza-dG-CE Phosphoramidite
CAS:<p>7-deaza-dG-CE Phosphoramidite is a monophosphate nucleotide, which is synthesized by modification of the 7-deaza-dG ribonucleoside. It has an antiviral and anticancer activity, and is used as a building block for novel drugs. 7-Deaza-dG-CE phosphoramidite has been shown to inhibit tumor growth and induce apoptosis in Hep2 cells. It also inhibits HIV replication in vitro. The compound is chemically stable and does not react with other biomolecules.</p>Formula:C44H54N7O7PPurezza:Min. 95%Peso molecolare:823.9 g/mol6-Azauridine-5'-monophosphate sodium
CAS:<p>Please enquire for more information about 6-Azauridine-5'-monophosphate sodium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C8H12N3O9P•(Na)2Peso molecolare:371.17 g/molUridine diphosphate choline (UDPC) sodium
CAS:<p>Uridine diphosphate choline (UDPC) sodium is a nucleotide that is used as a phosphoramidite for DNA synthesis. The chemical formula for UDPC is C8H14N4O8P. The activation of the molecule occurs in acidic conditions, which may be due to the formation of an amide bond between the terminal phosphate and the amino group on the phosphorylcholine. This same reaction can also occur in alkaline conditions. UDPC has been shown to inhibit viral replication, including HIV-1, by blocking reverse transcription of viral RNA into DNA. It also has anticancer effects, as it inhibits cell proliferation and induces apoptosis in cancer cells. UDPC does not have any known side effects or toxicity.</p>Formula:C14H25N3O12P2•NaPurezza:Min. 95%Colore e forma:PowderPeso molecolare:512.3 g/molN6-Methyl-N6-threonylcarbamoyladenosine
CAS:<p>N-(N'-Methyl-N-(9 beta-D-ribofuranosylpurin-6-yl)carbamyl)threonine is a nucleoside that is used in research.</p>Formula:C16H22N6O8Purezza:Min. 95%Peso molecolare:426.38 g/molCytidine-5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:Cytidine-5'-O-(1-thiotriphosphate) lithium salt is a monophosphate nucleotide analog. It is soluble in water, and is used in the synthesis of DNA and RNA. Cytidine-5'-O-(1-thiotriphosphate) lithium salt has antiviral, anticancer, and anti-inflammatory properties. This compound can be used as an activator for phosphoramidites in the synthesis of DNA or RNA. Cytidine-5'-O-(1-thiotriphosphate) lithium salt is a novel nucleoside that can be used in the synthesis of modified oligonucleotides.Formula:C9H16N3O13P3S·xLiPurezza:Min. 95%Peso molecolare:499.22 g/molXanthosine-5'-triphosphate triethylammonium salt - 100 mM aqueous solution
CAS:Inhibitor of adenylyl and guanylyl cyclaseFormula:C10H15N4O15P3·xC6H15NPurezza:Min. 95%Colore e forma:Colorless PowderPeso molecolare:524.17 g/mol8-Nitroguanosine
CAS:8-Nitroguanosine is a nucleotide analogue that inhibits the activity of cyclic GMP in cells. It has been found to inhibit the growth of bacteria and cancer cells, as well as to stimulate the production of reactive oxygen species in brain cells. 8-Nitroguanosine has also been shown to inhibit the activity of cyclase enzymes in liver cells, which may be useful for treating liver disease. 8-Nitroguanosine is used as a chemical base for monoclonal antibodies that are used to study brain functions and pathogenic mechanisms.Formula:C10H12N6O7Purezza:Min. 95%Peso molecolare:328.24 g/molDMT-2′O-TC-rG(ib) Phosphoramidite
CAS:DMT-2²O-TC-rG(ib) Phosphoramidite is a phosphoramidite that has been modified from the natural nucleoside DMT. It is a high purity, novel anticancer agent that has shown promising results in the treatment of cancer cells. The modifications on the phosphate group allow for enhanced phosphorylation which, in turn, leads to an increase in kinase activity. This modification also increases the stability of DNA and RNA synthesis, as well as protein synthesis.Formula:C49H61N8O11PS2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:1,033.16 g/mol9-(β-D-Arabinofuranosyl)adenine 5'-monophosphate
CAS:9-(β-D-Arabinofuranosyl)adenine 5'-monophosphate (Ara-AMP) is a prodrug that is converted to adenine arabinoside in vivo. It is used as an antiviral agent for the prevention of hepatitis B and C. Ara-AMP inhibits viral DNA synthesis by acting as a competitive inhibitor of adenosine triphosphate, which is required for viral DNA polymerase activity. Ara-AMP also has antiviral properties against some RNA viruses, such as HIV and influenza virus. Ara-AMP can be administered orally or by injection, making it suitable for use in children who are unable to take oral medication.Formula:C10H14N5O7PPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:347.22 g/mol5-Bromo-2'-deoxycytidine
CAS:5-Bromo-2'-deoxycytidine is a synthetic nucleoside analogue that is used to treat diabetic neuropathy. It is structurally similar to cytidine, and inhibits the enzyme DNA polymerase by intramolecular catalysis. This causes deamination of the 5-bromo group, which prevents further synthesis of DNA. 5-Bromo-2'-deoxycytidine has been shown to be effective in vivo in a mouse model for inflammatory bowel diseases, including colitis and eosinophilic enteritis. The drug was also found to inhibit the production of Eosinophil peroxidase from HL-60 cells in vitro.Formula:C9H12BrN3O4Purezza:Min. 95%Colore e forma:Off-White PowderPeso molecolare:306.11 g/molMorpholino A monomer
CAS:Morpholino A is a modified nucleoside amidite used to prepare morpholino oligomersFormula:C38H37ClN7O4PPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:722.17 g/molAdenosine 5′-O-(1-thiotriphosphate) sodium, mixture of R and S isomers
<p>Please enquire for more information about Adenosine 5′-O-(1-thiotriphosphate) sodium, mixture of R and S isomers including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C10H16N5O12P3S•Na3Purezza:Min. 95%Peso molecolare:592.25 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
CAS:<p>Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides containing 2’-O-(2-methoxyethyl) adenosine nucleoside units. Using a chemical approach rather than an enzymatic one allows custom-made oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with an appropriate alcohol in the presence of an azole catalyst such as imidazole or 1H-tetrazole. N6-Benzoyl-5'-O-DMT-2'-O-MOE-adenosine 3'-CE phosphoramidite has been used in the synthesis of 2’-modified oligonucleotides as protein binding modulators.</p>Formula:C50H58N7O9PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:932.01 g/molZeatin riboside
CAS:Zeatin riboside is a naturally occurring compound that belongs to the group of nucleotides. It is synthesized in plants and bacteria, and has been shown to have physiological activities in both these organisms. Rootstocks are typically used as the optimum concentration for zeatin riboside. Zeatin riboside has been shown to be effective against bacterial strains that cause plant diseases, such as bacterial strain Xanthomonas campestris pv. corylina. Zeatin riboside also inhibits the growth of plant pathogens by increasing adenine nucleotide levels in root cells, which leads to an increase in photosynthetic activity and a decrease in the production of chemical pesticides. The optimum pH for zeatin riboside is 8-9.Formula:C15H21N5O5Purezza:Min. 90%Colore e forma:PowderPeso molecolare:351.36 g/mol5-Aminoallyl uridine 5'-triphosphate sodium salt
CAS:<p>5-Aminoallyl uridine 5'-triphosphate sodium salt is used in Nucleic Acid Sequence Based Amplification or RNA labelling.</p>Formula:C12H20N3O15P3·xNaPurezza:Min. 95%Peso molecolare:539.22 g/mol2-Phenylaminoadenosine
CAS:2-Phenylaminoadenosine (2-PA) is a potent and selective inhibitor of the P2Y receptor. 2-PA has been shown to reduce myocardial infarct size in vivo in mice, which may be due to its ability to inhibit the release of dopamine from the brain. In addition, 2-PA binds to LPS receptors on endothelial cells, reducing the production of proinflammatory cytokines and preventing platelet aggregation. 2-PA also inhibits the activation of toll-like receptor 4 (TLR4) in human monocytes, leading to reduced expression of proinflammatory cytokines and increased expression of anti-inflammatory cytokines. 2-PA is an agonist that binds with high affinity to P2Y receptors on erythrocytes. This binding results in decreased adenosine triphosphate (ATP) production by adenosine deaminase, which leads to decreased intracellular calcium levels and inhibition of neutrophFormula:C16H18N6O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:358.35 g/mol3-Acetylpyridine adenine dinucleotide disodium, reduced form
CAS:<p>Reduced synthetic analog of NADH with an acetylpyridine modification. It is used as a reducing substrate to study the mechanisms of NAD(P)+-dependent reductases and to probe the active sites and catalytic processes of these important enzymes through its altered spectroscopic and binding properties. The disodium salt ensures good solubility for biochemical applications.</p>Formula:C22H30N6O14P2•Na2Purezza:Min. 95%Colore e forma:Slightly Yellow PowderPeso molecolare:710.43 g/molN6-Benzoyl-L-adenosine
CAS:N6-Benzoyl-L-adenosine is a novel nucleoside that has been shown to have antiviral and anticancer activity. It is synthesized by the reaction of L-adenosine with benzoyl chloride in the presence of a base. The drug inhibits the growth of cancer cells by interfering with DNA synthesis. N6-Benzoyl-L-adenosine also inhibits viral replication, especially HIV, herpes simplex virus type 1, and human cytomegalovirus (HCMV). It can be used as an antiviral agent in combination with other drugs or as an anticancer agent alone. N6 Benzoyl L adenosine is a nucleoside that has been shown to have antiviral and anticancer activity. It is synthesized by the reaction of L adenosine with benzoyl chloride in the presence of a base. The drug inhibits the growth of cancer cells by interfering with DNA synthesis. N6Formula:C17H17N5O5Purezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:371.35 g/molGuanosine5'-diphosphate
CAS:Pyruvate kinase substrateFormula:C10H15N5O11P2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:443.2 g/mol8-Iodoadenosine
CAS:<p>8-Iodoadenosine is a macrocyclic inhibitor that binds to the phosphate group on ATP. This binding prevents ATP from being hydrolyzed to ADP and inorganic phosphate, which inhibits the formation of ATP. 8-Iodoadenosine has been shown to inhibit the proliferation of some cancer cells by interfering with their ability to synthesize proteins. It has also been shown to be an effective treatment for parasitic infections caused by Entamoeba histolytica. 8-Iodoadenosine has also been shown to inhibit protein synthesis in bacteria, fungi, and parasites.</p>Formula:C10H12IN5O4Purezza:Min. 95%Peso molecolare:393.14 g/mol2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite
CAS:2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite is a fluorescent DNA probe that can be used for the detection of specific sequence mismatches in target DNA. This probe contains a linker, which is a short oligonucleotide, and a fluorescent label at the 5' end. The probe has been designed to hybridize to its complementary sequence in the target DNA. When it detects mismatches, it becomes fluorescent because of increased stacking interactions between the bases. This allows for easy detection of mismatches in target sequences without the need for PCR amplification or gel electrophoresis.Formula:C42H53N6O7PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:784.88 g/mol5′-O-DMT-LNA N-Bz adenosine
CAS:<p>5′-O-DMT-LNA N-Bz adenosine is a novel nucleoside that has been modified with an aminooxy group. The compound is synthesized by the phosphoramidite method and it is designed for use in antiviral and anticancer research. 5′-O-DMT-LNA N-Bz adenosine can be used as a substrate for DNA polymerases and other enzymes to produce nucleic acid strands. This product is CAS No. 206055-74-5, monophosphate, Phosphoramidites, Synthetic, Deoxyribonucleosides, Anticancer, Ribonuclesides, High purity.</p>Formula:C39H35N5O7Purezza:Min. 95%Peso molecolare:685.73 g/mol5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å
<p>5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å is a synthetic nucleoside that contains an acetyl group at the 5' position. The succinyl group has been added to the 3' position of the nucleoside and is bonded to a carrier molecule (2000 Å). This product is used as an activator in DNA synthesis, it also has antiviral and anticancer activities.</p>Colore e forma:PowderOleoyl coenzyme A lithium salt
CAS:Oleoyl coenzyme A lithium salt is a fatty acid that belongs to the class of organic compounds known as aliphatic acyl-coenzyme A. It is synthesized by the enzyme synthetase and can be used to diagnose cascading, linear response, and aldehyde synthesis in carbon nanotubes. Oleoyl coenzyme A lithium salt has been shown to bind to sephadex G-100 and immobilize it on a surface. This immobilization process aids in the diagnosis of various diseases such as diabetes mellitus, cancer, and cardiovascular problems. The chloride anion present in oleoyl coenzyme A lithium salt buffers and stabilizes the pH levels during this process. Oleoyl coenzyme A lithium salt also binds to multi-walled carbon nanotubes (MWNTs) due to its hydrophobic nature, which aids in the detection of markers such as lipids or proteins using immunological techniques.Formula:C39H68N7O17P3S·xLiPurezza:Min. 95%Peso molecolare:1,031.98 g/mol8-Aza-7-deaza-2'-deoxyguanosine
CAS:<p>8-Aza-7-deaza-2'-deoxyguanosine is an alkynylated, cross-linked, single stranded nucleic acid. It has been shown to be effective at cross-linking and cross-linking nucleic acids. 8-Aza-7-deaza-2'-deoxyguanosine binds to the 7 deazapurine residues in DNA, forming a covalent bond between the two strands of the helix. This binding prevents the strand from unwinding and prevents the replication of DNA. The thermodynamic data for this compound shows that it is stable in both hot and cold water, which makes it a good candidate for use in research as well as in clinical settings.</p>Formula:C10H13N5O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:267.24 g/mol(-)-Emtricitabine triphosphate sodium salt
CAS:Emtricitabine is a nucleoside reverse transcriptase inhibitor with activity against human immunodeficiency virus and hepatitis B virusFormula:C8H9FN3Na4O12P3SPurezza:Min. 95%Peso molecolare:575.11 g/mol3′-Guanylic acid disodium
CAS:<p>3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.</p>Formula:C10H14N5O8P•Na2Purezza:Min. 95%Peso molecolare:409.2 g/mol2-Chloroadenosine
CAS:2-Chloroinosine is an adenosine receptor agonist; metabolically stable analog of adenosineFormula:C10H12ClN5O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:301.69 g/molSpacer-c3 cep
CAS:<p>Spacer-C3 Cep is a novel modified nucleoside phosphoramidite. It has been chemically modified with a spacer arm and 3-Cep (1,2-diaminoethane). Spacer-C3 Cep is an activator for DNA polymerases, which are enzymes that synthesize DNA from deoxyribonucleosides. The modified nucleoside phosphoramidite has antiviral and anticancer activities. It can be used in the synthesis of oligodeoxyribonucleotides for gene therapy or as a monophosphate for the preparation of DNA probes. Spacer-C3 Cep can also be used to synthesize ribonucleotide analogs that inhibit viral replication by inhibiting RNA synthesis.</p>Formula:C33H43N2O5PPurezza:Min. 95%Peso molecolare:578.7 g/molPolyoxin B
CAS:<p>Polyoxin B is a natural product that is produced by the fungus Polyporus umbellatus. It is a synthetase inhibitor that specifically inhibits the enzyme malic acid synthetase in bacteria and fungi. Polyoxin B has been shown to have antifungal activity in vitro and to inhibit the growth of Cryptococcus neoformans, which may be due to its ability to inhibit terminal residues, such as acetate extract, bacterial strain, and synthase enzyme.</p>Formula:C17H25N5O13Purezza:Min. 70%Colore e forma:Yellow PowderPeso molecolare:507.41 g/molN6-Benzoyl-3'-deoxy-3'-fluoroadenosine
CAS:N6-Benzoyl-3'-deoxy-3'-fluoroadenosine is a nucleoside analog that is structurally similar to adenosine. It has antiviral and anticancer properties and can be used in the treatment of HIV and other viral infections. N6-Benzoyl-3'-deoxy-3'-fluoroadenosine inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which is required for DNA replication. This drug also binds to RNA polymerase, which is an enzyme required for RNA synthesis. N6-Benzoyl-3'-deoxy-3'-fluoroadenosine has been shown to have a high level of efficacy against leukemia cells in vitro as well as in vivo mouse models.Purezza:Min. 95%N2-Isobutyryl-O6-(4-pivaloyloxybenzyl)-7’-OH-N-trityl-morpholino guanine
CAS:N2-Isobutyryl-O6-(4-pivaloyloxybenzyl)-7’-OH-N-trityl-morpholino guanine is a phosphoramidite nucleoside that is used as a building block in the synthesis of oligonucleotides. N2-Isobutyrylguanosine is available as a high purity, high quality, and novel nucleoside that can be used in anticancer therapy. It has been shown to inhibit the growth of human cancer cells without affecting normal cells. This drug also inhibits DNA and RNA synthesis by inhibiting the enzyme ribonucleotide reductase.Purezza:Min. 95%Ribavirin 5'-triphosphate triethylammonium salt - 10 mM aqueous solution
CAS:<p>Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.</p>Formula:C8H15N4O14P3•(C6H15N)xPurezza:Min. 95 Area-%Colore e forma:Clear LiquidPeso molecolare:789.73Propionyl coenzyme A lithium salt
CAS:<p>Propionyl coenzyme A lithium salt is a phosphoramidite that can be used in the synthesis of DNA and RNA. It is a novel chemical compound that has been modified to include ribonucleosides in addition to deoxyribonucleosides. This product is of high purity and quality, with a CAS number of 108321-21-7.</p>Formula:C24H40N7O17P3S·xLiPurezza:85%Colore e forma:White PowderPeso molecolare:823.6 g/mol2'-Amino-2'-deoxycytidine
CAS:2'-Amino-2'-deoxycytidine is a modified nucleoside, based on cytidine. In this compound 2'-hydroxyl group has been replaced by an amino group, which can change hydrogen bonding patterns potentially affecting how it interacts with biomolecules.Formula:C9H14N4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:242.24 g/mol3'-Phosphoadenosine-5'-phosphosulfate lithium salt hydrate
CAS:Universal sulfonate donor for in vivo sulfonation by sulfotransferasesFormula:C10H15N5O13P2S·xLi·yH2OPurezza:Min. 60 Area-%Colore e forma:White PowderPeso molecolare:507.27 g/molm-Topolin riboside
CAS:Functionalised adenosine ribosideFormula:C17H19N5O5Purezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:373.36 g/molUridine 5'-triphosphate tris salt
CAS:<p>Uridine 5'-triphosphate tris salt is a pyrimidine nucleotide that is used in the synthesis of RNA. It has been shown to be an effective inhibitor of hamster ovary and human ovarian cells. Uridine 5'-triphosphate tris salt is water-soluble and does not interfere with cellular assays or microfluidic devices. Uridine 5'-triphosphate tris salt has also been shown to have potential as a model system for analytical chemistry and pharmacological research.</p>Formula:C13H26N3O18P3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:484.14 g/molATP-acetyl-desthiobiotin
<p>ATP-acetyl-desthiobiotin is a small molecule that inhibits the activity of tyrosine kinases. It has been shown to inhibit tumor growth in cultured cells and in mouse models, and is currently being evaluated in clinical trials for cancer treatment. ATP-acetyl-desthiobiotin is a competitive inhibitor of bosutinib (BST), an inhibitor of Bcr-Abl tyrosine kinase, which is associated with chronic myeloid leukemia. ATP-acetyl-desthiobiotin has also been shown to induce autophagy and inhibit cell proliferation, making it a potential anticancer drug.</p>Formula:C20H32N7O15P3Purezza:Min. 95%Peso molecolare:703.43 g/molAdenosine 2',3'-cyclic monophosphate
CAS:Adenosine 2',3'-cyclic monophosphate triethylammonium salt (AMP-TEA) is a structural analogue of adenosine. It is a potent inhibitor of protein synthesis by preventing the phosphodiesterase activity of cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase. AMP-TEA can be used as a tool to study translation in tissue culture, as well as to examine the effects on protein synthesis and other biochemical reactions that are regulated by cyclic nucleotides. It is also used for the preparation of tissue samples for enzymatic analysis or for radiolabeling experiments. AMP-TEA has an optimum pH of 4.5, but can be used at lower or higher pH values. The optimal temperature range for use is between 0°C and 50°C, with the maximum stability occurring at 37°C.Formula:C10H12N5O6PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:329.21 g/mol
