Nucleosidi

6-Azacytidine is a molecule that contains a hydroxyl group and a glycosidic bond. It has been shown to inhibit the growth of mollicutes, which are non-cellular bacteria. 6-Azacytidine has also been shown to be toxic in animal tissue culture studies. The drug can be eliminated through the urine or bile after being metabolized by the liver. 6-Azacytidine is not active against human cells in cell culture, but it does show some toxicity against human liver cells.

1-(2'-Deoxy-2'-fluoro-α-L-arabinofuranosyl)-thymine (commonly abbreviated as L-FMAU) is a nucleoside analog. It contains an α-L-arabinofuranose sugar instead of the natural β-D-deoxyribose found in DNA. A fluorine (F) substitution at the 2'-position enhances stability and resistance to enzymatic degradation. The thymine nucleobase allows it to mimic natural thymidine, potentially incorporating into DNA synthesis pathways. It can be research for its potential antiviral activity.

<p>2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine is a nucleoside that is used in the production of DNA and RNA. It is an activator of phosphoramidites, which are used to synthesize oligonucleotides. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can be used as an anti-cancer drug and has antiviral activity. It has been shown to inhibit the replication of HIV by interfering with viral enzymes such as reverse transcriptase and integrase. 2'-Deoxy-5'-O-DMT-2'-trifluoroacetamidouridine can also be used for the treatment of influenza A virus infections. This drug is highly purified, with a high quality, monophosphate form as well as a diphosphate form. There are no known side effects associated with this product.!--</p>

6-Amino-3-iodo-4-methoxy-1-(beta-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and can be used to synthesize DNA and RNA. 6AIOMP binds to the ribonucleotide reductases in cells and inhibits their activity. This prevents the conversion of ribonucleotides into deoxyribonucleotides, which are essential for DNA synthesis.

<p>5’-O-DMT-2’-b-C-methyladenosine is a modified nucleoside with antiviral and anticancer activity. It is an activator of DNA synthesis, and can be used as a precursor for phosphoramidites for the synthesis of oligonucleotides. The 5’-O-DMT group in this compound may be replaced with other activating groups to synthesize different modified nucleosides.</p>

3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine is a novel synthetic nucleoside that has been shown to have anticancer and antiviral activities. The compound is an activator of the immune system, which may be due to its ability to stimulate the production of interferon and other cytokines. 3'-Amino-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine can also inhibit viral DNA polymerases. This nucleoside has been shown to inhibit the growth of leukemia cells in culture by inhibiting ribonucleotide reductase activity.

<p>3’-deoxy-3’-fluorosangivamycin is a modified deoxyribonucleoside with antiviral and anticancer properties. It is an activator of DNA polymerase. 3’-deoxy-3’-fluorosangivamycin has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) in the calf thymus DNA system. This drug is also effective against other viruses, such as herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and influenza A virus. 3′-deoxy-3′-fluorosangivamycin binds to viral DNA and inhibits nucleotide incorporation, leading to inhibition of viral RNA synthesis and protein synthesis.</p>

<p>6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a novel synthetic ribonucleotide that inhibits the growth of tumor cells by interfering with DNA synthesis. This compound has been shown to inhibit the replication of HIV and herpes simplex virus type 1. The phosphoramidite monomer is readily available and can be synthesized in high purity and high quality. 6-Amino-4-hydroxyamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is activated by phosphorylation at the 5' position. CAS No.: 10266890</p>

5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a monophosphate nucleoside that inhibits viral replication by inhibiting the synthesis of both DNA and RNA. This compound is used to treat cancers such as leukemia, lymphoma, and multiple myeloma. It also has antiviral properties that are active against herpes simplex virus (HSV) and human cytomegalovirus (CMV). 5'-Carboxy-2-chloro-2'-3'-O-isopropylideneadenosine is a modified nucleoside with a phosphoramidite group on the 2' position of the ribose sugar.

<p>Pseudothymidine is the nucleobase analog of thymidine. It is a synthetic substance that has been used in the polymerase chain reactions (PCRs) to form DNA molecules. Pseudothymidine is not naturally found in cells and can be used as a substitute for thymidine during PCR to make more copies of DNA sequences. It has been shown that pseudothymidine can be incorporated into DNA without disrupting the polymerase chain reaction. The thermal denaturation of pseudothymidine is 10 °C lower than that of thymidine, allowing it to be used at higher temperatures with less risk of degradation.</p>

2,3'-Anhydrouridine 5'-CE phosphoramidite is a novel modified phosphoramidite that can be used in the synthesis of ribonucleosides and DNA. It has antiviral activity, and is being studied as an anticancer drug. 2,3'-Anhydrouridine 5'-CE phosphoramidite has been shown to inhibit the replication of HIV-1 and herpes simplex virus type 1 (HSV-1). The nucleoside analogs are being studied for their potential use in chemotherapy.

Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxycytidine including the price, delivery time and more detailed product information at the technical inquiry form on this page

5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.

<p>Please enquire for more information about 3’-beta-Azido-2’,3’-dideoxy-5-fluorouridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

5'-O-Tritylthymidine is a nucleoside that is found in human mitochondrial DNA. It is synthesized from uridine by the enzyme thymidylate synthase and can be converted to thymine by the enzyme thymidine phosphorylase. 5'-O-Tritylthymidine has been shown to inhibit cancer cell growth, but its mechanism of action is not clear. It may inhibit xylene production. 5'-O-Tritylthymidine also causes an increase in p53 activity, which may lead to apoptosis of cancer cells.

<p>N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine is a novel nucleoside that can be used as an antiviral agent. It is an activator of viral polymerase and inhibits the proliferation of cells infected with HIV. This compound has been synthesized from 2'-deoxyadenosine monophosphate, which is a precursor to RNA and DNA synthesis. N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine has also been shown to inhibit the growth of experimental tumors in mice. The synthesis of this compound is reliable and reproducible, making it a high quality product.</p>

<p>3'-O-Methyl-5-methylcytidine is a nucleoside with antiviral and anticancer properties. It has been shown to be an activator of RNA polymerase, the enzyme that catalyzes the transcription of DNA into RNA. 3'-O-Methyl-5-methylcytidine binds to the active site of RNA polymerase and is able to stimulate transcription in vitro. This drug has also been shown to have high purity and high quality.</p>

N4-Benzoyl-2'-deoxy-2'-fluorocytidine 3'-CE phosphoramidite is a novel DNA phosphoramidite monomer that has been modified to include an N4-benzoyl group at the 2'-position of the sugar. It is synthesized from 4,5-diaminopyrimidine, 1,3-bis(2-chloroethyl)carbodiimide hydrochloride (EDC), and 4-(N,N-dimethylamino)benzoic acid. The benzoyl group allows for the incorporation of this monomer into DNA in place of deoxycytidine. This product is designed to be used in oligonucleotide synthesis as an activator.

Amino functionalised thymidine

<p>Please enquire for more information about 3'-O-Aminoacetoxy-2'-deoxyguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

L-Adenosine 5'-monophosphate disodium is a high quality, novel, modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. It is also used as an antiviral agent and has anti-cancer properties. L-Adenosine 5'-monophosphate disodium is an activator of ribonucleoside activities and inhibits viral replication by inhibiting the enzyme RNA polymerase. It has been shown to be effective against HIV, herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), influenza A virus, and influenza B virus.

<p>3’-b-C-Methylcytidine is a nucleoside analog that inhibits the viral enzyme reverse transcriptase and is used as an antiviral agent. 3’-b-C-Methylcytidine binds to DNA and prevents RNA synthesis, which is essential for viral replication. It has been shown to inhibit the growth of cultured cells from human breast cancer and melanoma, suggesting that it also has anticancer activity. 3’-b-C-Methylcytidine can be synthesized in high purity and at high yield using phosphoramidites. This nucleoside analog may be useful in clinical applications due to its ability to activate transcription, which may lead to novel therapeutic strategies.</p>

5'-Azido-2',5'-dideoxy-2'-fluorouridine is a novel nucleoside that is a phosphoramidite. It is an antiviral agent that has been shown to inhibit the synthesis of RNA in cells. This drug also inhibits the growth of cancer cells and can be used for the treatment of leukemia, lymphoma, and myeloma. 5'-Azido-2',5'-dideoxy-2'-fluorouridine has been shown to bind to DNA through its azide group and form a stable covalent bond with the N7 position of guanine. This bond prevents the incorporation of adenosine triphosphate (ATP) into DNA, which prevents DNA transcription and replication.

2-Chloro-2',3'-O-isopropylideneadenosine is a novel, anti-cancer drug that inhibits the synthesis of DNA. It is a phosphoramidite monophosphate with a molecular weight of 288.08 g/mol and an empirical formula C6H12ClNO5PS. The chemical name for this compound is 2-chloro-N-(2,3-diisopropyl)adenine diphosphate. This product has not yet been approved by the FDA for use in humans or animals.

Clofarabine is FDA-approved for treating relapsed or refractory acute lymphoblastic leukaemia (ALL) in children after at least two other types of treatment have failed

<p>3'-Deoxy-2'-O-methyladenosine is a nucleoside that has antiviral and anticancer activity. It is a novel chemical compound with a unique structure, which makes it highly reactive. 3'-Deoxy-2'-O-methyladenosine induces DNA synthesis and cell proliferation in cancer cells. It also inhibits the production of viral DNA and RNA in infected cells by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 3'-Deoxy-2'-O-methyladenosine can be used as an antiviral agent against herpes simplex virus type 1 (HSV1), herpes simplex virus type 2 (HSV2) and human cytomegalovirus (CMV).</p>

2-Chloro-N6-cyclopentyladenosine hemihydrate is a synthetic adenosine analog with potential research applications

<p>2'-O-(2-Methoxyethyl)uridine is a nucleoside analog that inhibits the synthesis of DNA, RNA and protein. It can be used as an antimetabolite to treat cancer and prevents tumor growth by interfering with cell division. 2'-O-(2-Methoxyethyl)uridine is often used in combination with other chemotherapeutic drugs. This drug is not active against bacteria and does not inhibit the growth of bacteria. The major disadvantage of this drug is its lack of efficacy against tumors, which may be due to the lack of penetration through the cell membrane or damage to DNA caused by radiation, abiotic factors, or malfunctioning enzymes. 2'-O-(2-Methoxyethyl)uridine has been shown to cause damage to cells by altering their metabolism and affecting the function of their mitochondria. Damage can cause cells to die through apoptosis or necrosis.</p>

<p>6-Thioinosine is a nucleoside analog that is chemically related to 6-mercaptopurine. It inhibits the polymerase chain reaction and has been shown to inhibit aerobic metabolism in aerobacter aerogenes. It also inhibits the growth of hl-60 cells, which are derived from human leukemia cells. 6-Thioinosine has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. It also blocks the activity of certain receptors and has a disease activity against infectious diseases such as systemic candidiasis, bacterial endocarditis, and bowel disease.</p>

<p>5-b-D-Ribofuranosyl-2(1H)-pyridinone is a phosphoramidite that is used in the synthesis of DNA. It is also an antiviral and anticancer agent. 5-b-D-Ribofuranosyl-2(1H)-pyridinone may be modified to include deoxyribonucleosides or ribonucleosides, which are important for DNA synthesis. 5-b-D-Ribofuranosyl-2(1H)-pyridinone is a novel chemical compound with a high purity and quality.<br>5 b D Ribofuranosyl 2 1 H Pyridinone CAS No 188871 50 3 Activator monophosphate High purity High quality DNA Synthetic Deoxyribonucleosides Novel Modified Ribonuclesides Nucleosides</p>

<p>Nucleoside phosphoramidite used in oligonucleotide synthesis</p>

<p>3'-O-Methyladenosine (3'OMeA) is a monomethylated adenosine that belongs to the group of nucleosides. It has been found to inhibit the activity of adenosine receptors, which are important for the regulation of blood pressure and central nervous system function. 3'OMeA also inhibits virus replication in human lymphocytes. 3'OMeA is synthesized by reaction with methylamine and purification by column chromatography. The molecule is a potential therapeutic target for HIV/AIDS, as it can be used as a specific agonist in order to block viral entry into cells.</p>

<p>Incorporated in DNA/RNA hybrids and mismatch pairs to analyse helix stability</p>

N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesis

<p>Kinetin riboside-5'-diphosphate sodium salt is a synthetically modified nucleoside that is used as an activator for DNA synthesis and in the treatment of cancer. Kinetin riboside-5'-diphosphate sodium salt has been shown to have antiviral and anticancer effects, as well as being able to modify the activity of natural substances such as kinetin. This compound has been shown to inhibit tumor growth and reduce the size of some types of tumors in mice. It also inhibits viral replication by blocking viral RNA polymerase activity and inhibiting viral protein synthesis.</p>

1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)uracil is a synthetic antiviral agent that inhibits the activity of DNA and RNA polymerases. It also has anticancer properties. The compound is an analogue of 2'-deoxycytidine monophosphate (dCMP). This compound binds to the phosphate group of nucleoside triphosphates and prevents their incorporation into DNA or RNA. 1-(4’-Azido-3’,5’-di-O-benzoyl-2’-deoxy) -2′ fluoro -b D arabinofuranosyl) uracil has been shown to inhibit the growth of cancer cells in vitro.

BBQ-650-DT CEP is an antiviral compound that is a phosphoramidite derivative of cytidine. BBQ-650-DT CEP has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and other retroviruses in vitro, and to inhibit tumor cell proliferation in vivo. BBQ-650-DT CEP also inhibits the synthesis of RNA and DNA, which may have anticancer properties. This compound has been shown to be active against leukemia cells, lymphoma cells, and various breast cancer cell lines. It has also been shown to induce apoptosis in leukemia cells.

amino functionalised nucleoside

N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is an antiviral compound that inhibits the synthesis of DNA and RNA. It is a synthetic, modified nucleoside with antiviral properties. The compound has been shown to be active against both animal and human tumor cells, as well as being effective in the treatment of viral infections.N6-Benzoyl-7-deaza-2'-deoxy-7-iodoadenosine is water soluble and biologically stable.

Zebularine 3'CE phosphoramidite is a novel, high quality activator for modified DNA monophosphate. It is used as an anticancer drug and antiviral agent. Zebularine 3'CE phosphoramidite is a synthetic, diphosphate with high purity and high reactivity. It has been shown to activate deoxyribonucleosides to ribonucleosides in DNA synthesis, as well as being able to inhibit viral RNA synthesis by inhibiting viral polymerase.

3'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. 3'-O-Benzoyl-2'-deoxyuridine is also an antiviral agent that has shown efficacy against HIV, HSV, and influenza virus. 3'-O-Benzoyl-2'-deoxyuridine is a phosphoramidite monophosphate that can be used as a building block for DNA or RNA synthesis. It is also a diphosphate that can be used to synthesize modified nucleosides. This product has novel properties and high purity, making it suitable for research purposes.

<p>2,4,6-Trichloro-5-methylpyrimidine is a nucleoside for use in research applications</p>

<p>3',5'-Diamino-3',5'-dideoxythymidine (ddT) is a cytosine analog that inhibits the growth of cells by interfering with DNA replication. This drug is effective against viruses such as herpes, which are dependent on deoxycytidine for replication. 3',5'-Diamino-3',5'-dideoxythymidine binds to the viral DNA and prevents it from being used as a template for viral RNA synthesis. It also has potent antiviral activity against l1210 and uninfected mice. 3',5'-Diamino-3',5'-dideoxythymidine is not charged and does not penetrate tissues well because of its large size. It also has limited effects on bacterial enzymes.</p>

N4-Benzoyl-3'-deoxycytidine is a novel antiviral agent that has shown activity against DNA and RNA viruses. It is an activator of DNA polymerase, which is essential for replication of viral nucleic acids. The compound is a modified nucleoside with a benzoyl group at the 4' position of the ribose moiety. It also has phosphoramidite, monophosphate, and diphosphate analogues. N4-Benzoyl-3'-deoxycytidine binds to the enzyme DNA polymerase, thereby inhibiting its ability to synthesize deoxyribonucleotides from ribonucleotides. This results in inhibition of viral DNA synthesis and subsequent inhibition of viral replication.

2'-Deoxy-7-deazaisoguanosine triphosphate is a nucleotide analogue that is used as an antiviral agent in the treatment of HIV. It has potent activity against HIV and other retroviruses, including SIV, FIV, and HTLV-1. 2'-Deoxy-7-deazaisoguanosine triphosphate has been shown to act as an activator of DNA polymerase by enhancing the incorporation of deoxynucleotide triphosphates into DNA. It also inhibits the synthesis of viral DNA by inhibiting the activity of reverse transcriptase enzymes. 2'-Deoxy-7-deazaisoguanosine triphosphate can be synthesized from diphosphates and phosphoramidites through a modified phosphoramidite approach that allows for high quality and purity with high yield.

<p>5-Methoxycarbonylmethyluridine is a nucleoside that is a precursor in the synthesis of other nucleotides. It has been shown to have potential as a biomarker for various diseases, such as metabolic disorders and hepatic steatosis. 5-Methoxycarbonylmethyluridine also inhibits the activity of methyltransferases, which are enzymes that catalyze the transfer of methyl groups from S-adenosylmethionine to substrates. It is also used as a model system for polymerase chain reaction in cancer research, because it has been shown to inhibit DNA replication by blocking the incorporation of uracil into DNA.<br>5-Methoxycarbonylmethyluridine has been found at high levels in fetal bovine serum and eukaryotic cells, but not in prokaryotes or cancerous tissues.</p>

N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-O-succinate triethylamine salt is a synthetic antiviral agent that can be used in the treatment of HIV. This drug inhibits the viral DNA polymerase and prevents virus replication. N4-Benzoyl-2'-deoxy-5'-O-DMT cytidine 3'-O succinate triethylamine salt is a novel nucleoside analogue with a monophosphate group at the 5' position and an N4 benzoyl group at the 2' position. It is an activator of DNA synthesis, which can be used for cancer chemotherapy. The chemical name for this drug is CAS No. 74405-44-0 (free base).

2'-Azido-2'-deoxy-5'-O-DMT-uridine is a nucleoside that has been modified with an azido group at the 2' position. The azido group is used to modify DNA and RNA nucleosides, which are monophosphate, ribonucleosides, and deoxyribonucleosides. This drug may be used as an activator of DNA synthesis or as a antiviral agent. It has been shown to inhibit HIV replication in vitro.

5'-Azido-5'-deoxyuridine is a synthetic nucleobase that is used in the synthesis of oligodeoxynucleotides. It has been shown to have an inhibitory effect on tumor cells, which may be due to its ability to interact with guanosine diphosphate (GDP) and prevent the formation of GTP. 5'-Azido-5'-deoxyuridine has also been shown to have an inhibitory effect on Mycobacterium tuberculosis and Mycobacterium avium complex, but does not affect other bacteria. 5'-Azido-5'-deoxyuridine interacts with RNA by binding to the phosphate group and inhibiting the synthesis of proteins and DNA.

2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a purine nucleoside where the purine base has a 2-amino group at position 2 and a chlorine at position 6. The sugar is 2'-deoxy, meaning it is like the sugar found in DNA, lacking the 2'-hydroxyl group that is present in RNA. The amino and chloro groups on the purine base modify how this molecule behaves in biological systems making it useful in research applications.