Nucleosidi
Trovati 3569 prodotti di "Nucleosidi"
2'-Azido-2'-deoxyguanosine
CAS:2'-Azido-2'-deoxyguanosine is an analog of guanine that is used as a fluorescent probe in biochemical and chemical biology studies. It can be synthesized using the azide method, which involves coupling an azide functional group to an aromatic ring. 2'-Azido-2'-deoxyguanosine can also be modified by a number of modifications, including attachment of fluorescent molecules or biotin for labeling purposes. The chemical structure of this compound has been shown to have a conformation that is similar to that of natural guanosine and uridine. 2'-Azido-2'-deoxyguanosine can be detected by proton nuclear magnetic resonance spectroscopy at about 3 ppm, which corresponds to its chemical shift in the range of 200–300 Hz. This compound also has biochemical properties that are similar to those observed for natural guanine and uridine.Formula:C10H12N8O4Purezza:Min. 95%Peso molecolare:308.25 g/molAdenosine-5'-[-(propargyl)]triphosphate sodium salt
Adenosine-5'-[-(propargyl)]triphosphate sodium salt is a modified nucleoside with anticancer activity. It has been shown to be a potent activator of DNA synthesis and an inhibitor of viral replication. Adenosine-5'-[-(propargyl)]triphosphate sodium salt is not active against bacterial cells, but it can be used in the treatment of cancer. This drug also has antiviral effects, which may be due to its ability to inhibit viral replication by binding to viral RNA polymerases or by inhibiting the transcriptional activation of genes encoding for enzymes that are required for mRNA synthesis.Formula:C13H18N5O13P3Purezza:Min. 95%Peso molecolare:545.23 g/mol1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine
CAS:1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine is a nucleoside that is used in the synthesis of DNA. It is a novel, synthetic nucleoside that has been modified to contain a 2'-O-4-C methylene bridge and an additional ribose moiety at the 3' position. This modification increases the stability of the nucleotide, making it more resistant to degradation by phosphodiesterases. 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine may be used as an antiviral agent against HIV and influenza A virus. The compound has also shown anticancer activities in mice with leukemia induced by busulfan.Formula:C11H13N5O5Purezza:Min. 95%Peso molecolare:295.25 g/mol5-Fluorouridine
CAS:5-Fluorouridine is an anticancer drug that belongs to the group of modified nucleosides. It is a synthetic nucleoside analogue that inhibits viral and DNA synthesis and can be used as antiviral agents. 5-Fluorouridine has also been shown to inhibit RNA synthesis in vitro. This compound is converted to uracil by deoxyribonucleotide reductase, which results in the formation of 5-fluoro-2'-deoxyuridine monophosphate (5FdUMP) and 5-fluoro-2'-deoxyuridine diphosphate (5FdUDP). The latter has been shown to inhibit DNA synthesis in vitro.
Formula:C9H11FN2O6Purezza:Min. 95%Peso molecolare:262.19 g/mol2'-OMe-5-Me-U ce-phosphoramidite
CAS:Please enquire for more information about 2'-OMe-5-Me-U ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C41H51N4O9PPurezza:Min. 95%Peso molecolare:774.8 g/mol5-Chloro-2',3'-O-isopropylideneuridine
CAS:5-Chloro-2',3'-O-isopropylideneuridine (5Cl-2',3'-O-diP) is a nucleoside that is used in the synthesis of DNA and RNA. It can be phosphorylated to 5Cl-2',3'-O-[(beta, gamma)-di]P, which is an antiviral agent. 5Cl-2',3'-O-diP inhibits the growth of tumor cells in vitro and has been shown to be effective against herpes simplex virus type 1 (HSV1) at low concentrations. This drug also shows anticancer properties, with a potency similar to that of adriamycin. 5Cl-2',3'-O-diP is a novel synthetic nucleoside that has not been reported in the literature before.Formula:C12H15ClN2O6Purezza:Min. 95%Peso molecolare:318.72 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine is an antiviral compound that inhibits the synthesis of viral RNA. This nucleoside analog is a monophosphate and diphosphate inhibitor of ribonucleotide reductase, which is required for DNA and RNA synthesis. N4-Benzoylcytosine has also been shown to be cytotoxic against tumor cells in vitro and in vivo, making it a potential anticancer drug. It was synthesized as part of a novel series of compounds that have been shown to inhibit the growth of bacterial cultures, including Mycobacterium tuberculosis.Formula:C37H34FN3O7Purezza:Min. 95%Peso molecolare:651.7 g/mol4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate
4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate is a synthetic nucleotide that can be activated to form an antiviral and anticancer agent. This compound has been shown to inhibit the proliferation of leukemia cells in culture. It also inhibits the synthesis of DNA and RNA, leading to cell death by inhibiting the production of proteins vital for cell division. 4,5-Dimethoxy-2-nitrobenzyl adenosine 3',5'-cyclic monophosphate is a novel nucleoside with high purity and CAS number: 57314-27-1.Formula:C19H21N6O10PPurezza:Min. 95%Peso molecolare:524.38 g/mol3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
CAS:3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine is a nucleoside that is modified with a tert-butyldimethylsilyl group at the 3' position. It is used as an activator for synthesizing oligonucleotides, ribonucleosides, and phosphoramidites. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine has antiviral and anticancer properties. This product can be used in research applications such as the synthesis of novel DNA and RNA molecules, as well as for diagnostic purposes such as detecting viral infections.Formula:C36H44N2O8SiPurezza:Min. 95%Peso molecolare:660.83 g/mol2'-Deoxyguanosine-5'-monophosphate free acid
CAS:2'-Deoxyguanosine-5'-monophosphate free acid (dGMP) is a nucleotide that can be used as a substrate to measure the activity of protein kinase C. It is also a precursor in DNA synthesis, and its incorporation into DNA is catalyzed by polymerase chain reaction. 2'-Deoxyguanosine-5'-monophosphate free acid has been shown to inhibit transcriptional regulation, which may be related to its interaction with nuclear DNA. Furthermore, it has been shown to have an antioxidant effect due to its ability to donate electrons. 2'-Deoxyguanosine-5'-monophosphate free acid has also been shown to react with sodium salts in plasma mass spectrometry experiments, and titration calorimetry experiments have shown that it reacts with calcium ions in vitro.br>Formula:C10H14N5O7PPurezza:Min. 95%Peso molecolare:347.22 g/mol2’-O-(2-Methoxy-2-oxoethyl)adenosine
CAS:2’-O-(2-Methoxy-2-oxoethyl)adenosine is a novel antiviral and anticancer agent. It is an antiviral due to its ability to inhibit viral DNA synthesis and replication by competitively inhibiting the incorporation of deoxyribonucleoside triphosphate precursors into viral DNA. 2’-O-(2-Methoxy-2-oxoethyl)adenosine has been shown to be active against human cancer cells in vitro and in vivo, as well as other cell lines. This compound is a phosphoramidite that can be used for the synthesis of modified oligonucleotides, including ribonucleosides and deoxyribonucleosides. 2’-O-(2-Methoxy-2-oxoethyl)adenosine has also been shown to be an activator of RNA polymerase II transcriptional activity.Purezza:Min. 95%2'-Deoxy-5'-O-DMT-5-propargyloxyuridine
2'-Deoxy-5'-O-DMT-5-propargyloxyuridine is a nucleoside analogue that is an activator of the antiviral enzyme ribonuclease L. It has been shown to be cytotoxic in cell culture and has also been shown to induce apoptosis in human leukemia cells. 2'-Deoxy-5'-O-DMT-5-propargyloxyuridine is a novel modified nucleoside that has a high purity.Formula:C33H32N2O8Purezza:Min. 95%Peso molecolare:584.63 g/mol5-O-DMT-thymidine 3'-H phosphonate triethylammonium
5-O-DMT-thymidine 3'-H phosphonate triethylammonium is a novel nucleoside analogue with anticancer activity. The monophosphate form of 5-O-DMT-thymidine 3'-H phosphonate triethylammonium is an activator of DNA, RNA, and protein synthesis in vitro. 5-O-DMT-thymidine 3'-H phosphonate triethylammonium has been shown to be active against herpes simplex virus type 1 and 2 and HIV type 1 in vitro.
Formula:C37H48N3O9PPurezza:Min. 97 Area-%Colore e forma:White/Off-White SolidPeso molecolare:709.77 g/molBiotinTEG Phosphoramidite
CAS:BiotinTEG Phosphoramidite is a medicinal compound that acts as an inhibitor of cancer cell growth. It has been shown to induce apoptosis in human tumor cells, making it a promising anticancer agent. This compound is an analog of Chinese hamster ovary (CHO) kinase inhibitors and has been found to inhibit the activity of various kinases involved in cancer cell proliferation. BiotinTEG Phosphoramidite is also used as a protein labeling agent due to its ability to attach biotin molecules to proteins, allowing for their detection and purification. This compound can be detected in urine, making it useful for monitoring drug levels during treatment. Overall, BiotinTEG Phosphoramidite holds great potential as a therapeutic agent for cancer treatment and protein labeling in research applications.
Formula:C52H76N5O11PSPurezza:Min. 95%Peso molecolare:1,010.2 g/mol3-Deaza-2'-Deoxyadenosine
CAS:3-Deaza-2'-Deoxyadenosine is a nucleoside analog that is synthesized from 2'-deoxyadenosine. It has been shown to be more potent than natural adenosine in inhibiting the activity of certain RNA polymerases. 3-Deaza-2'-Deoxyadenosine inhibits RNA synthesis by binding to the ribose moiety of the ribonucleotide, which prevents the formation of an enzyme-substrate complex and thus blocks chain elongation. This compound is also able to inhibit DNA synthesis by binding to the deoxyribose moiety of DNA and preventing DNA polymerase from adding nucleotides to the growing strand. 3-Deaza-2'-Deoxyadenosine has been shown to have antiviral activity against influenza virus and herpes simplex virus type 1 (HSV) in vitro.Formula:C11H14N4O3Purezza:Min. 95%Peso molecolare:250.25 g/mol5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carbonitrile
CAS:5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carbonitrile is a novel nucleoside analogue that inhibits the viral enzyme ribonucleotide reductase. It has antiviral activity against the herpes viruses, cytomegalovirus, and Epstein Barr virus. 5AADC has also been shown to inhibit DNA synthesis in tumor cells. This compound is currently undergoing clinical trials as an anticancer agent.Formula:C15H18N4O7Purezza:Min. 95%Peso molecolare:366.33 g/mol2-Amino-6-chloro-7-methyl-9-(b-D-ribofuranosyl)purine
CAS:2-Amino-6-chloro-7-methyl-9-(b-D-ribofuranosyl)purine is a nucleoside which is the structural analog of adenosine and is used in the synthesis of DNA, RNA, and other nucleosides. It has antiviral activity against herpes simplex virus type 1 and 2, Epstein Barr virus, poliovirus types 1, 2, and 3, and vesicular stomatitis virus. This compound also has anticancer activity. 2-Amino-6-chloro-7-methyl-9-(b-D ribofuranosyl) purine can be used to synthesize deoxyribonucleosides or monophosphate nucleotides. It can also be used as an intermediate for phosphoramidites in the synthesis of DNA or RNA.Formula:C11H16ClN5O4Purezza:Min. 95%Peso molecolare:317.73 g/mol3'-Azido-N4-benzoyl-5'-O-trityl-2',3'-dideoxyadenosine
3'-Azido-N4-benzoyl-5'-O-trityl-2',3'-dideoxyadenosine is a novel nucleoside that has been described as an activator of diphosphate. It is a modified deoxyribonucleoside, with the amino group in the ribose moiety replaced by an azido group. This nucleotide inhibits viral and cellular DNA synthesis by blocking DNA polymerase. 3'-Azido-N4-benzoyl-5'-O-trityl-2',3'-dideoxyadenosine can also be used for anticancer purposes, where it has been shown to inhibit cancer cell growth.Formula:C36H30N8O3Purezza:Min. 95%Peso molecolare:622.68 g/mol2'-o-Butyryladenosine 3',5'-cyclic phosphate dmap
CAS:Please enquire for more information about 2'-o-Butyryladenosine 3',5'-cyclic phosphate dmap including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C14H18N5O7PPurezza:Min. 95%Peso molecolare:399.3 g/mol5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine
5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine is an activated nucleoside phosphoramidite for the synthesis of DNA and RNA. It is a building block for various nucleic acid analogues and has been shown to have antiviral and anticancer properties. 5'-O-DMT-3'-O-hexylphthalimido-5-methyluridine is also known as N6 -(2,4,6 trimethoxybenzoyl) adenosine or 5'-O-(2,4,6 triisopropoxybenzoyl)-adenosine (TIBA) and is used in the laboratory to produce oligonucleotides with modified sugar groups. This product has been shown to be effective against a number of cancer cell lines and has potential use in chemotherapy.
Formula:C45H47N3O10Purezza:Min. 95%Peso molecolare:789.89 g/molN6-Benzoyl-7'-OH-morpholino adenosine
CAS:N6-Benzoyl-7'-OH-morpholino adenosine is a modified nucleoside with antiviral activity. It is being developed as an activator of ribonucleotide reductase and a potential anticancer agent. N6-Benzoyl-7'-OH-morpholino adenosine is synthesized by reacting benzoyl chloride with 7'-O-dimethoxytritylmorpholine. This reaction results in the formation of the desired product, which has been shown to be an activator of ribonucleotide reductase. The synthesis of this compound can be performed on a large scale, making it an attractive candidate for chemotherapeutic use.Formula:C17H18N6O3Purezza:Min. 95%Colore e forma:SolidPeso molecolare:354.36 g/mol2,5-Dioxo-3-sulfo-1-pyrrolidinyl 6-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]amino]hexanoate sodium salt
CAS:2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite is a nucleotide analog that is used for the treatment of cancer. It inhibits sugar transport, which leads to tumor cell lysis. 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite binds to glut1 and toll-like receptor 4 in the cell membrane, inhibiting the activation of these cells. This drug has been shown to have an antibody response in myeloma cells and basic fibroblast cell lines.Formula:C20H30N4O9S2•NaPurezza:Min. 95%Peso molecolare:557.60 g/mol4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite
CAS:4-(2-Cyanoethylthio)-2'-deoxy-5'-DMT-uridine 3'-CE phosphoramidite is a novel DNA synthesis inhibitor that is synthesized by the reaction of 4-(2-cyanoethylthio)-2'-deoxy-5'-DMT-uridine and phosphorous oxychloride. This product has antiviral and anticancer activities, as well as high purity and high quality. It can be used in cellular biology research, including the study of ribonucleosides, nucleosides, and deoxyribonucleosides. This product also inhibits HIV replication in vitro.Formula:C42H50N5O7PSPurezza:Min. 95%Peso molecolare:799.93 g/mol5-Hydroxy-DC CEP
CAS:Please enquire for more information about 5-Hydroxy-DC CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C53H56N5O10PPurezza:Min. 95%Peso molecolare:954 g/mol2'-Deoxy-5'-O-DMT-guanosine
CAS:2'-Deoxy-5'-O-DMT-guanosine is a purine nucleoside that is converted to 2'-deoxy-5'-O-DMT-adenosine by the enzyme deoxyadenosyltransferase. This conversion is necessary for the synthesis of adenosylcobalamin, which is essential for the methylation of homocysteine to methionine. 2'-Deoxy-5'-O-DMT-guanosine has been shown to have cancer chemopreventive effects in vitro and in vivo. It also has been shown to enhance dna hybridization and hydrophobic interactions with cancerous cells, which may be due to its ability to inhibit gene expression.
Formula:C31H31N5O6Purezza:Min. 95%Peso molecolare:569.61 g/mol2'-Deoxy-N2-isopropylguanosine
CAS:2'-Deoxy-N2-isopropylguanosine is a nucleoside that is synthesized from 2'-deoxy-N6-methyladenosine and isopropyl alcohol. It has antiviral and anticancer properties. The antiproliferative effects of this drug are mediated by the inhibition of DNA synthesis in cells. This compound also inhibits the activation of the transcriptional factor NF-κB, which regulates inflammatory responses in the body.Formula:C13H19N5O4Purezza:Min. 95%Peso molecolare:309.33 g/mol5'-O-DMT-cytidine
CAS:5'-O-DMT-cytidine is a modified nucleoside that is used as an activator for phosphoramidites and as a building block for DNA, RNA, and other nucleic acids. 5'-O-DMT-cytidine has been shown to have anticancer and antiviral properties in laboratory tests. It is also known to inhibit the replication of HIV virus by blocking the reverse transcriptase enzyme. The compound is available with high purity and high quality. This product can be synthesized into a diphosphate, monophosphate or ribonucleotide form.
Formula:C30H31N3O7Purezza:Min. 95%Peso molecolare:545.58 g/molS-Adenosyl-L-methionine
CAS:S-Adenosyl-L-methionine (SAM-e) is a co-substrate involved in methyl group transfer to nucleic acids, proteins and lipids. SAM-e is produced in the liver from adenosine triphosphate (ATP) and methionine by action of the enzyme methionine adenosyltransferase. Therapeutic use of S-adenosyl-L-methionine includes osteoarthritis, liver disease and major depressive disorder. S-Adenosyl-L-methionine is available as a dietary supplement.Formula:C15H22N6O5SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:398.44 g/mol(5'S)-2'-Deoxy-8,5'-cycloadenosine
CAS:(5'S)-2'-Deoxy-8,5'-cycloadenosine is a nucleoside analog that blocks the synthesis of DNA. It is a glycosylated nucleoside that contains an 8-carbon fatty acid chain linked to the 5’ carbon of the sugar ring. This compound is formed from the reaction of (5'S)-2'-deoxyadenosine and dicyclohexylcarbodiimide. The biological properties of this drug are not well understood, but it has been shown to be reactive with physiological levels and able to induce neuronal death in an experimental model. The mechanism for this effect is unknown, but may involve intramolecular hydrogen bonding or hydrolysis by esterases. A molecular docking analysis was performed to study the binding affinity between (5'S)-2'-deoxy-8,5'-cycloadenosine and human mda-mb-231 breast cancer cells. This analysis showed that wild
Formula:C10H11N5O3Purezza:Min. 95%Peso molecolare:249.23 g/mol1-Hydroxyethyl-2'-deoxyadenosine
CAS:1-Hydroxyethyl-2'-deoxyadenosine (1HEDA) is an antiviral drug that inhibits the synthesis of viral DNA by blocking the formation of a ribonucleoside triphosphate intermediate. 1HEDA is a novel monophosphate nucleoside that has been modified to be resistant to phosphodiesterase enzymes and can be used as a chemotherapeutic agent for cancer. 1HEDA has been shown to have anticancer activity in vitro, in vivo, and in human clinical trials.Formula:C12H17N5O4Purezza:Min. 95%Peso molecolare:295.29 g/molGuanosine 5'-[γ-thio]triphosphate tetralithium
CAS:Guanosine 5'-[γ-thio]triphosphate tetralithium (GTPγS) is a guanine nucleotide analog that has been shown to modulate the signal transduction pathway in many types of cells. GTPγS activates the extracellular signal-transducing receptor kinase and phospholipase C, which are involved in cellular proliferation and differentiation. This agent also blocks calcium channels, thereby inhibiting neuromuscular transmission. It has been shown to be effective against pertussis toxin and other agents that block G protein coupling by inhibiting adenylate cyclase. In addition, GTPγS inhibits staurosporin-sensitive K+ channels in some neuronal cells, but not those that are insensitive to this blocker.Formula:C10H12Li4N5O13P3SPurezza:Min. 90 Area-%Colore e forma:PowderPeso molecolare:562.98 g/molGuanylyl-3'-5'-uridine ammonium salt
CAS:Guanylyl-3'-5'-uridine ammonium salt is a nucleoside compound that has been synthesized to inhibit the growth of cancer cells. The guanylyl-3'-5'-uridine monophosphate (GMP) is an activator of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. It also inhibits DNA synthesis by inhibiting the activity of DNA polymerase and DNA gyrase, which are enzymes that maintain the integrity of DNA. Guanylyl-3'-5'-uridine ammonium salt has been shown to be active against leukemia and colon cancer cells in vitro and in vivo.
Formula:C19H24N7O13P·NH3Purezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:606.45 g/mol2-tert-Butylpyrimidine-5-carbaldehyde
CAS:2-tert-Butylpyrimidine-5-carbaldehyde (2BP) is a potent, selective inhibitor of DNA polymerase that is expressed in the tibia during bone development. 2BP has been shown to inhibit platelet-derived growth factor (PDGF)-induced angiogenesis in mouse calvaria and animal research models. This compound also inhibits the proliferation of basic fibroblasts and cancer cells in vitro.Formula:C9H12N2OPurezza:Min. 95%Peso molecolare:164.2 g/mol2',3'-Dideoxycytidine 5'-monophosphate
CAS:Dideoxycytidine 5'-monophosphate (DDCMP) is a molecule that inhibits HIV infection by inhibiting the synthesis of DNA. It binds to the dna template strand, preventing the addition of new nucleotides and thus blocking the progression of HIV infection. DDCMP has been shown to be potent in vitro and in vivo in clinical studies. In cell culture, DDCMP has been shown to inhibit DNA duplexes, leading to a decrease in lymphocytic leukemia cells activated by T-cell receptor stimulation. Structural biology studies have revealed that DDCMP inhibits HIV-1 reverse transcriptase through binding at the M2 subunit of the enzyme's active site.
Formula:C9H14N3O6PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:291.2 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Sp-oxazaphospholidine
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Sp-oxazaphospholidine is a modified nucleoside that is synthesized from the amino acid phenylalanine. It has anticancer activity and is an activator of ribonucleosides. This compound also has novel properties, including high purity and high quality. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Sp-oxazaphospholidine can be used as a phosphoramidite to synthesize DNA or deoxyribonucleosides and diphosphates.Purezza:Min. 95%ent-idoxuridine
CAS:Ent-idoxuridine is a cytosolic DNA synthesis inhibitor that blocks the conversion of deoxycytidine to deoxyadenosine by inhibiting the enzyme deoxycytidine kinase. It is also an enantiomer of idoxuridine, which has the same mechanism of action. Ent-idoxuridine is not active against herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). In contrast to idoxuridine, ent-idoxuridine is resistant to exonucleases and has been shown to be effective in treating immunodeficiency caused by HIV.Formula:C9H11IN2O5Purezza:Min. 95%Peso molecolare:354.1 g/mol4'-Hydroxymethyl-4,5',8-trimethylpsoralen (hmt)
CAS:4'-Hydroxymethyl-4,5',8-trimethylpsoralen (HMT) is an analog of psoralen that has been shown to have potent anti-tumor activity. HMT acts as an inhibitor of human tumor kinase and has been shown to induce apoptosis in cancer cells. This drug has also been found to enhance the effects of other cancer treatments, such as nintedanib. HMT has demonstrated potential for the treatment of diabetes by acting as an inhibitor of glucose uptake and metabolism in Chinese hamster ovary cells. Additionally, HMT has been found to have inhibitory effects on enzymes such as apomorphine, glimepiride, and vanillin. Overall, HMT holds great promise for the development of novel cancer therapies and diabetes treatments.Formula:C15H14O4Purezza:Min. 95%Peso molecolare:258.27 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxyadenosine
CAS:N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxyadenosine is an antiviral, monophosphate nucleoside that has been shown to inhibit the proliferation of human leukemia cells. The compound is a novel synthetic nucleoside that inhibits the viral reverse transcriptase enzyme and prevents RNA synthesis. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxyadenosine also inhibits DNA synthesis by inhibiting the activity of DNA polymerases and can be used for the treatment of cancer.Purezza:Min. 95%5-Carboxymethylaminomethyl- 2'-O-methyluridine
CAS:5-Carboxymethylaminomethyl- 2'-O-methyluridine (5CmAMU) is a modified nucleobase that is categorized as a modified base. It is an analog of uridine, which has been shown to be effective against tuberculosis in mice. 5CmAMU inhibits the methylation of rRNA and DNA by binding to the enzyme RNA methyltransferase, thereby inhibiting transcription and replication. This modification has also been shown to inhibit cellular proliferation and promote apoptosis. 5CmAMU binds to guanine with a stoichiometry of 1:1, which provides evidence for its role in DNA synthesis and repair. The structural modifications on this molecule may lead to diagnostic applications or treatments for diseases such as tuberculosis.Formula:C13H19N3O8Purezza:Min. 95%Colore e forma:PowderPeso molecolare:345.31 g/mol4-Amino-1-[(2R,3R,4R,5R)-3-ethoxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
CAS:4-Amino-1-[(2R,3R,4R,5R)-3-ethoxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one is a novel compound that is an anticancer agent and antiviral. It inhibits the proliferation of cells by modifying the nucleotide structure of DNA. The 4'-amino group makes it a nucleoside analogue that can be modified to inhibit bacterial replication and virus production. 4'-Amino-1-[(2R,3R,4R,5R)-3-ethoxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-- 2 one may also cause cell death by inhibiting DNA synthesis and RNA synthesis.Formula:C11H17N3O5Purezza:Min. 95%Peso molecolare:271.27 g/mol2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde
CAS:2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde is an antiviral and anticancer phosphoramidite. It is a novel monophosphate nucleoside analogue that inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase. 2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde has been shown to be effective against influenza virus, HIV, Herpes Simplex Virus, and human leukemia cells. This compound is not active against bacteria or fungi.Formula:C10H13N3OPurezza:Min. 95%Peso molecolare:191.23 g/mol5-Chloro-5'-deoxy-2',3'-O-isopropylidenecytidine
5-Chloro-5'-deoxy-2',3'-O-isopropylidenecytidine is a synthetic nucleoside that has antiviral and anticancer properties. It binds to the DNA of viruses and inhibits their replication, as well as the synthesis of DNA in cancer cells. This nucleoside also activates ribonucleotide reductase, which is an enzyme that converts ribonucleotides into deoxyribonucleotides. 5-Chloro-5'-deoxy-2',3'-O-isopropylidenecytidine is a novel nucleoside analog that can be phosphoramidite or monophosphate.Formula:C12H16ClN3O4Purezza:Min. 95%Peso molecolare:301.73 g/molE-5-(2-Carboxyvinyl)-2'-deoxyuridine hydroxysuccinimide ester
CAS:E-5-(2-Carboxyvinyl)-2'-deoxyuridine hydroxysuccinimide ester is a nucleoside analog that inhibits the growth of cells by inhibiting DNA synthesis. It is an antiviral and anticancer agent, as well as a potential therapeutic for human immunodeficiency virus (HIV) and herpes simplex virus (HSV). This compound also has high purity and high quality, which makes it suitable for research purposes. E-5-(2-Carboxyvinyl)-2'-deoxyuridine hydroxysuccinimide ester is novel and has been modified from the natural nucleoside uridine. It can be used in the synthesis of phosphoramidites for DNA synthesis, which are used to synthesize DNA probes for use in diagnostic medicine.Formula:C16H17N3O9Purezza:Min. 95%Peso molecolare:395.32 g/mol3'-Deoxy-N6-lauroyladenosine
CAS:3'-Deoxy-N6-lauroyladenosine is a nucleoside analog that is used to treat cancer. It is a phosphoramidite compound and it has been shown to be highly active against cancer cells. 3'-Deoxy-N6-lauroyladenosine is an antiviral agent that inhibits viral DNA synthesis by competing with the natural substrate, deoxyribonucleosides, for incorporation into the growing DNA chain. It also prevents the replication of RNA viruses by inhibiting their transcription and translation processes. 3'-Deoxy-N6-lauroyladenosine also inhibits inflammation in the body and may act as a chemotherapeutic agent in other diseases such as diabetes, Alzheimer's disease, and Parkinson's disease.
Formula:C22H35N5O4Purezza:Min. 95%Peso molecolare:433.54 g/mol5-Ethynylcytidine
CAS:5-Ethynylcytidine is a fluorescent analog of cytosine that has been synthesized for use in biochemical research. It is used to identify cellular sites of RNA synthesis and replication, as well as to study the role of the 5-ethynyl group in the mechanism of DNA methylation. The synthetic route starts with an azide intermediate which is then treated with sodium hydroxide, followed by hydrolysis and demethylation. 5-Ethynylcytidine has been shown to be selective for mammalian cells and tissues, and was incubated with calf thymus DNA for crystallographic data.Formula:C11H13N3O5Purezza:Min. 95%Peso molecolare:267.24 g/mol2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine
CAS:2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a novel nucleotide analog that exhibits anticancer activity. It has been shown to inhibit the growth of human leukemia cells and enhance the cytotoxic effect of doxorubicin. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is a potent inhibitor of DNA synthesis with a high selectivity index for cancer cells. This agent inhibits DNA synthesis by competing with deoxyribonucleosides for incorporation into the growing DNA strand. 2,6-Bis-o-[2-(4-nitrophenyl)ethyl]-2'-deoxyxanthosine is an activator at the adenine phosphoribosyltransferase (APRT) enzyme and may also have an effect on ribonucleotide reductase (RFormula:C26H26N6O9Purezza:Min. 95%Peso molecolare:566.5 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine is a synthetic nucleoside analog that is used as an antiviral agent. It inhibits the activity of reverse transcriptase, which is an enzyme that synthesizes DNA from RNA. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5 methylcytosine has been shown to be active against human immunodeficiency virus type 1 (HIV), herpes simplex virus type 2 (HSV), and cytomegalovirus (CMV). The drug has also been shown to be potent in inhibiting the replication of HIV in cell culture.
Formula:C38H36FN3O7Purezza:Min. 95%Peso molecolare:665.72 g/mol5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3',5'-cyclic monophosphothioate, Sp-isomer sodium salt
CAS:5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3',5'-cyclic monophosphothioate, Sp-isomer sodium salt (SPP) is a cytostatic agent that binds to the α subunit of the voltage-dependent Ca2+ channel. It has been shown to inhibit tumor growth in mouse models of hyperproliferative diseases such as bladder cancer and pulmonary fibrosis. SPP also inhibits the proliferation of human bladder cells in culture by inhibiting cyclic nucleotide phosphodiesterase activity. This leads to an increase in intracellular calcium concentrations and activation of cation channels. SPP is an analog of rolipram, which has been shown to have anti-inflammatory effects on detrusor muscle cells.Formula:C12H10Cl2N2O5P·NaPurezza:Min. 95%Peso molecolare:419.16 g/mol6-Azathymidine ce-phosphoramidite
CAS:Please enquire for more information about 6-Azathymidine ce-phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C39H48N5O8PPurezza:Min. 95%Peso molecolare:745.8 g/molL-5-methyluridine
CAS:L-5-methyluridine is a nucleoside that is used as a building block in the synthesis of oligonucleotides. It contains one ribose sugar and one deoxyribose sugar, linked to the base adenine by a phosphate group. L-5-methyluridine can be synthesized from 5-chloro-2'-deoxyadenosine, hypoxanthine, and ammonium chloride. The synthesis starts with condensation reactions between the two sugar molecules to form an intermediate called a nucleoside. This is followed by alkylation of the base and then oxidation of the sugar group to form anomeric esters. The last step involves hydrolysis of the acyloxy ester, which yields L-5-methyluridine after acidification.Formula:C10H14N2OPurezza:Min. 95%Peso molecolare:178.23 g/mol
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