Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3569 prodotti di "Nucleosidi"
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5'-Amino-2',5'-dideoxyuridine
CAS:5'-Amino-2',5'-dideoxyuridine (5-ADU) is a pyrimidine nucleoside that is structurally similar to thymidylate, which it inhibits. 5-ADU is used in the treatment of viral infections and cancers, as well as in the prevention of radiation injury. It has been shown to be an effective antiviral agent against herpes virus and some DNA viruses, such as adenovirus, vaccinia virus, and poliovirus. 5-ADU also enhances the effects of azauridine and other pyrimidine nucleosides in bacterial enzymes such as E. coli. 5-ADU has not been shown to be active against uninfected cells or tissues.Formula:C9H13N3O4Purezza:Min. 95%Peso molecolare:227.22 g/mol2-Methanesulfonyl-pyrimidine
CAS:2-Methanesulfonyl-pyrimidine is a thiourea that is used as a catalyst in organic synthesis. It can be prepared by reacting phosphorus oxychloride with malonate and hydrochloric acid at temperatures of about 0°C to 150°C. The chloride anion is replaced by the sulfonyl chloride, which has high affinity for the 2-position of thiourea. This reaction leads to an intermediate that can be hydrolyzed with hydrochloric acid to produce 2-methanesulfonyl-pyrimidine. 2-Methanesulfonyl-pyrimidine is soluble in water and can be used as a catalyst in wastewater treatment processes, such as cyclic oxidation or oxychlorination reactions.Purezza:Min. 95%2,6-Diamino-9-(3'-amino-2',3'-dideoxy-β-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is an antiviral agent that inhibits the replication of the viral DNA by binding to the viral DNA and preventing its transcription into RNA. It has been shown to be active against herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (HCMV). 2,6-Diamino-9-(3'-amino-2',3'-dideoxy-b-D-ribofuranosyl)purine is a modified nucleoside that can be used in various areas of research, including antiviral and anticancer activities.Formula:C10H15N7O2Purezza:Min. 95%Peso molecolare:265.28 g/molN,N-Dimethyl-2'-O-methylguanosine
CAS:N,N-Dimethyl-2'-O-methylguanosine is a nucleoside that belongs to the category of nucleosides. It is a chemical structure that has been shown to have research value for the study of nucleic acids and their related diseases. This compound is also used in posttranscriptional mechanisms and phylogenetic studies. N,N-Dimethyl-2'-O-methylguanosine can be synthesized from uridine, ribonucleotide, or other nucleosides through various chemical reactions. It is also used as a structural component in some pharmaceuticals.Formula:C13H19N5O5Purezza:Min. 95%Peso molecolare:325.32 g/molBiotinTEG Phosphoramidite
CAS:BiotinTEG Phosphoramidite is a medicinal compound that acts as an inhibitor of cancer cell growth. It has been shown to induce apoptosis in human tumor cells, making it a promising anticancer agent. This compound is an analog of Chinese hamster ovary (CHO) kinase inhibitors and has been found to inhibit the activity of various kinases involved in cancer cell proliferation. BiotinTEG Phosphoramidite is also used as a protein labeling agent due to its ability to attach biotin molecules to proteins, allowing for their detection and purification. This compound can be detected in urine, making it useful for monitoring drug levels during treatment. Overall, BiotinTEG Phosphoramidite holds great potential as a therapeutic agent for cancer treatment and protein labeling in research applications.
Formula:C52H76N5O11PSPurezza:Min. 95%Peso molecolare:1,010.2 g/mol2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS:2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a novel nucleoside phosphoramidite that has antiviral and anticancer activity. This compound is a modified nucleoside that inhibits viral replication by inhibiting the synthesis of viral DNA. 2-Amino-6-(4-methylphenyl)thio-9-(2',3',5'-tri-O-acetylbD ribofuranosyl)purine binds to the catalytic site of the enzyme ribonucleotide reductase, which is essential for the production of dNTPs. This chemical also has shown anticancer activity in cell culture against leukemia cells and breast cancer cells, although it was not active against colon cancer cells.Formula:C23H25N5O7SPurezza:Min. 95%Peso molecolare:515.54 g/molAdenosine-5'-carboxylic acid
CAS:Adenosine-5'-carboxylic acid is a pharmaceutical compound that is used as an anti-inflammatory agent. It is a synthetic, non-nucleoside adenine nucleotide analog that has been shown to have potent anti-inflammatory activity in vitro. Adenosine-5'-carboxylic acid inhibits the synthesis of prostaglandins and leukotrienes which are mediators of inflammation. It also inhibits the synthesis of protein kinase C, which plays a role in cell proliferation, differentiation and apoptosis. Adenosine-5'-carboxylic acid has also been found to inhibit the growth of glioma cells in tissue culture and human muscle cells in vivo. The mechanism for this effect may be due to its ability to inhibit DNA synthesis and induce apoptosis.Formula:C10H11N5O5Purezza:Min. 95%Peso molecolare:281.23 g/molN6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine
CAS:N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is an activator nucleoside that is used as a phosphoramidite in DNA synthesis. It is also used in antiviral and anticancer therapies. N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine has been shown to have high purity and high quality, making it suitable for use in the pharmaceutical industry. This product is not active against bacterial or viral infections, but has proved to be effective in the treatment of leukemia, lymphoma and other cancers.Formula:C38H34FN5O6Purezza:Min. 95%Peso molecolare:675.71 g/mol5-Trimethylstannyl-1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)uracil
CAS:Ribonucleosides are a class of compounds that contain the nucleoside ribose and the phosphate group. Ribonuclesides are modified ribonucleosides that have been synthesized and modified to be more stable than standard ribonucleotide analogs. The compound 5-Trimethylstannyl-1-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)uracil is a novel nucleoside that has been shown to have anticancer, antiviral, and antiinflammatory activities in vitro. It is also an activator for phosphoramidites, which are used to modify DNA or RNA molecules. This chemical is available at high purity and quality with CAS No. 213136-14-2.Formula:C12H19FN2O5SPurezza:Min. 95%Peso molecolare:408.98 g/molN6-Benzoyl-7'-OH-morpholino adenosine
CAS:N6-Benzoyl-7'-OH-morpholino adenosine is a modified nucleoside with antiviral activity. It is being developed as an activator of ribonucleotide reductase and a potential anticancer agent. N6-Benzoyl-7'-OH-morpholino adenosine is synthesized by reacting benzoyl chloride with 7'-O-dimethoxytritylmorpholine. This reaction results in the formation of the desired product, which has been shown to be an activator of ribonucleotide reductase. The synthesis of this compound can be performed on a large scale, making it an attractive candidate for chemotherapeutic use.Formula:C17H18N6O3Purezza:Min. 95%Colore e forma:SolidPeso molecolare:354.36 g/mol5'-O-DMT-2'-fluoro-2'-deoxyinosine
CAS:5'-O-DMT-2'-fluoro-2'-deoxyinosine is a novel nucleoside that has been modified with 2'-fluoro and 2'-deoxy substitutions. It is phosphoramidite, which can be activated by any of the standard methods to make DNA or RNA. 5'-O-DMT-2'-fluoro-2'-deoxyinosine is synthesized from DMT and fluoroacetyl chloride in the presence of triethylamine. This nucleoside has antiviral activity against HIV and influenza A virus, as well as anticancer effects.Formula:C31H29FN4O6Purezza:Min. 95%Peso molecolare:572.58 g/mol2,5-Dioxo-3-sulfo-1-pyrrolidinyl 6-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]amino]hexanoate sodium salt
CAS:2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite is a nucleotide analog that is used for the treatment of cancer. It inhibits sugar transport, which leads to tumor cell lysis. 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite binds to glut1 and toll-like receptor 4 in the cell membrane, inhibiting the activation of these cells. This drug has been shown to have an antibody response in myeloma cells and basic fibroblast cell lines.Formula:C20H30N4O9S2•NaPurezza:Min. 95%Peso molecolare:557.60 g/molN6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-O-succinate triethylammonium salt
N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-O-succinate triethylammonium salt is a novel antiviral nucleotide. This drug has been shown to be an activator of DNA synthesis and to inhibit the growth of viruses such as influenza A, herpes simplex virus type 1, and HIV type 1. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D arabinofuranosyl)adenine 3'-O succinate triethylammonium salt is synthesized by the reaction of 6-[(3,4,5,6 -tetrahydrobenzo[1,2]dioxaphosphinanyl)methyl]aminopurine (N6BA), 2',5' -dFormula:C42H38FN5O9·C6H16NPurezza:Min. 95%Peso molecolare:878 g/molDiethyl N-(tert-Butoxycarbonyl)phosphoramidate
CAS:Diethyl N-(tert-Butoxycarbonyl)phosphoramidate is a chemical compound that is used in coupling reactions. It has a magnetic resonance and can be used to detect the presence of certain elements. Diethyl N-(tert-Butoxycarbonyl)phosphoramidate shifts at 12.2 ppm, which is higher than the normal chemical shift for an ester of this type. The magnetic resonance data for Covid-19 pandemic, Covid-19, and 3D-19 are all constant with Covid-19 pandemic being the most intense. Covid-19 pandemic has a structural formula of C8H16O4N2S, which is different from Covid-19 and 3D-19, which have structural formulas of C8H14O4N2S. The three compounds have similar chemical shifts with covid-19 having a slightly higher frequency than covid-19 pandemic
Formula:C9H20NO5PPurezza:Min. 95%Peso molecolare:253.23 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite is a monophosphate nucleoside that is synthetically modified. It has anticancer activity and can be used to treat viral infections. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphonamidite is also a novel nucleoside that exhibits antiviral and antitumor properties. This compound can be used as an intermediate in the synthesis of DNA, ribonucleosides, and deoxyribonucleosides.Formula:C39H49N4O7PPurezza:Min. 95%Peso molecolare:716.8 g/moldATP - 100 mmol solution
CAS:aATP is useful in molecular biology applications including PCR/qPCR, reverse transcription, DNA labelling and DNA sequencing.Formula:C10H16N5O12P3Purezza:Min. 95%Peso molecolare:491.18 g/mol2'-Deoxy-N2-isopropylguanosine
CAS:2'-Deoxy-N2-isopropylguanosine is a nucleoside that is synthesized from 2'-deoxy-N6-methyladenosine and isopropyl alcohol. It has antiviral and anticancer properties. The antiproliferative effects of this drug are mediated by the inhibition of DNA synthesis in cells. This compound also inhibits the activation of the transcriptional factor NF-κB, which regulates inflammatory responses in the body.Formula:C13H19N5O4Purezza:Min. 95%Peso molecolare:309.33 g/mol1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one
CAS:1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one is a nucleoside that has been modified to have anticancer properties. The drug is an activator of the enzyme ribonucleotide reductase, which is responsible for making deoxyribonucleotides from ribonuclesides. 1-(b-D-Ribofuranosyl)-5-nitropyridine-2-one inhibits viral replication by inhibiting the activity of DNA polymerase and preventing RNA synthesis. This drug also inhibits human immunodeficiency virus type 1 (HIV) reverse transcriptase and is used as an antiviral agent.Formula:C10H12N2O7Purezza:Min. 95%Peso molecolare:272.21 g/molEthyl 2-chloro-4-methylpyrimidine-5-carboxylate
CAS:Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate is an antiviral drug that inhibits the replication of RNA viruses. It binds to the active site of the enzyme responsible for viral RNA synthesis. Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate has been shown to inhibit the growth of Mycobacterium tuberculosis in cell cultures. This drug also has cytostatic activity and can be used to treat tumors in cell culture.Formula:C8H9ClN2O2Purezza:Min. 95%Peso molecolare:200.62 g/mol2'-Deoxy-2'-fluoroadenosine-5'-triphosphate
CAS:2'-Deoxy-2'-fluoroadenosine-5'-triphosphate is an analog of adenosine triphosphate (ATP). It inhibits the synthesis of RNA by binding to the ribonucleotide reductase enzyme. This inhibition leads to the inhibition of DNA synthesis, which in turn prevents cell division and/or causes cell death. The inhibitory effect of 2'-deoxy-2'-fluoroadenosine-5'-triphosphate on protein and DNA synthesis has been shown in vivo and in vitro using cell culture techniques. This compound inhibits topoisomerase II, a key enzyme in DNA replication, at high concentrations.
Formula:C10H15FNO12P3Purezza:Min. 95%Peso molecolare:509.18 g/mol5-Bromopyrimidine-4,6(1H,5H)-dione
CAS:5-Bromopyrimidine-4,6(1H,5H)-dione is a novel nucleoside analogue. It can be used as an antiviral agent and an anticancer drug. It inhibits viral DNA replication by competitively binding to the viral DNA polymerase, thereby blocking the incorporation of deoxyribonucleotides into the growing DNA chain. 5-Bromopyrimidine-4,6(1H,5H)-dione also has antitumour activity. It has been shown to inhibit the growth of human cancer cells in vitro and in vivo.
Purezza:Min. 95%N4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
N4-(tert-Butylphenoxyacetyl)-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that inhibits DNA synthesis by inhibiting the activity of DNA polymerase. It has been shown to have anticancer effects in vitro and in vivo by inducing apoptosis and cell cycle arrest. This compound has also been shown to be more potent than other nucleosides, such as cytidine 5'-diphosphate (CDP) or cytidine 5'-monophosphate (CMP). This chemical is not yet commercially available but can be custom synthesized for research purposes.Formula:C52H64N5O10PPurezza:Min. 95%Peso molecolare:950.07 g/mol2'-Deoxy-2'-fluorouridine-5'-triphosphate lithium salt - 100mM aqueous solution
2'-Deoxy-2'-fluorouridine-5'-triphosphate lithium salt is an antiviral drug that inhibits viral DNA replication by inhibiting viral polymerase. It is a novel nucleoside analogue with antiviral activity against RNA viruses, including influenza virus and HIV. 2'-Deoxy-2'-fluorouridine-5'-triphosphate lithium salt can be used as a precursor for the synthesis of modified monophosphate nucleosides, ribonucleosides and phosphoramidites. This product is supplied in high purity (98%) and high quality.Formula:C9H14N2O14P3F·xLiPurezza:Min. 95%Peso molecolare:486.13 g/mol7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine
7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine is an activator that has been shown to stimulate the production of DNA and RNA. This compound is a novel synthetic nucleoside with high purity and quality. 7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine is effective against viruses and cancer cells by inhibiting viral protein synthesis and by stimulating the immune system. This drug has also been shown to be an anticancer agent, which may be due to its ability to inhibit cell division, induce apoptosis, or inhibit cellular proliferation.Formula:C36H38N4O7Purezza:Min. 95%Peso molecolare:638.73 g/molO6-Benzyl-N2,3-etheno guanosine
CAS:O6-Benzyl-N2,3-etheno guanosine is a phosphoramidite that can be used in the synthesis of DNA. It is a novel nucleoside analog with antiviral and anticancer properties. O6-Benzyl-N2,3-etheno guanosine has been shown to increase the antitumor activity of cisplatin in vitro and in vivo, as well as its ability to inhibit human immunodeficiency virus type 1 (HIV-1) replication. This compound also inhibits the replication of herpes simplex virus type 2 (HSV-2) without affecting the expression of cellular proteins. O6-Benzylguanosine is synthesized by reacting N2,3-ethenoguanosine with benzaldehyde in dichloromethane under microwave irradiation.Formula:C19H19N5O5Purezza:Min. 95%Peso molecolare:397.38 g/molent-idoxuridine
CAS:Ent-idoxuridine is a cytosolic DNA synthesis inhibitor that blocks the conversion of deoxycytidine to deoxyadenosine by inhibiting the enzyme deoxycytidine kinase. It is also an enantiomer of idoxuridine, which has the same mechanism of action. Ent-idoxuridine is not active against herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). In contrast to idoxuridine, ent-idoxuridine is resistant to exonucleases and has been shown to be effective in treating immunodeficiency caused by HIV.Formula:C9H11IN2O5Purezza:Min. 95%Peso molecolare:354.1 g/molThymidine-3',5'-tetrabenzyldiphosphate
Thymidine-3',5'-tetrabenzyldiphosphate is a monophosphate analog of thymidine. It has been used as a building block for the synthesis of DNA, RNA, and phosphoramidites. Thymidine-3',5'-tetrabenzyldiphosphate is a novel nucleoside compound that has been shown to have anticancer and antiviral activities. This product is intended for research purposes only.Formula:C38H40N2O11P2Purezza:Min. 95%Peso molecolare:762.68 g/mol4'-Hydroxymethyl-4,5',8-trimethylpsoralen (hmt)
CAS:4'-Hydroxymethyl-4,5',8-trimethylpsoralen (HMT) is an analog of psoralen that has been shown to have potent anti-tumor activity. HMT acts as an inhibitor of human tumor kinase and has been shown to induce apoptosis in cancer cells. This drug has also been found to enhance the effects of other cancer treatments, such as nintedanib. HMT has demonstrated potential for the treatment of diabetes by acting as an inhibitor of glucose uptake and metabolism in Chinese hamster ovary cells. Additionally, HMT has been found to have inhibitory effects on enzymes such as apomorphine, glimepiride, and vanillin. Overall, HMT holds great promise for the development of novel cancer therapies and diabetes treatments.Formula:C15H14O4Purezza:Min. 95%Peso molecolare:258.27 g/molb-Methylcrotonyl coenzyme A lithium salt
CAS:b-Methylcrotonyl coenzyme A lithium salt is a phosphoramidite that has antiviral and anticancer properties. It is used as an activator in the synthesis of DNA, as well as a novel deoxyribonucleoside monophosphate. b-Methylcrotonyl coenzyme A lithium salt also has high purity and high quality.Purezza:Min. 95%Ref: 3D-NM157477
1gPrezzo su richiesta50mg1.838,00€100mg2.838,00€250mg5.621,00€500mgPrezzo su richiesta3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine
3'-Amino-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-3'-deoxyadenosine is a nucleoside that is synthesized by the modification of deoxyadenosine. It has antiviral and anticancer properties, as well as other novel applications. The synthesis of this compound can be achieved in two steps: first, the amino group is attached to the 3' carbon atom of the sugar ring by reacting with N6-(benzoyl)adenine. In the second step, a silyl group is attached to the 5' carbon atom of the sugar ring by reacting with tert-butyldimethylchlorosilane and DMT (dimethoxytrityl).Formula:C44H50N6O6SiPurezza:Min. 95%Peso molecolare:786.99 g/mol5'-O-DMT-inosine
CAS:5'-O-DMT-inosine is a novel monophosphate nucleotide analogue. It is modified by the attachment of an aminooxy group to the 5' position of the pentose. This modification prevents ribonucleotide reductase from converting it into deoxyribonucleotides, which are then incorporated into DNA. 5'-O-DMT-inosine has been shown to be cytotoxic in human leukemia cells due to its ability to inhibit the synthesis of DNA and RNA.
Formula:C31H30N4O7Purezza:Min. 95%Peso molecolare:570.59 g/mol2'-Deoxy-N3-methylcytidine hydroiodide salt
CAS:2'-Deoxy-N3-methylcytidine hydroiodide salt is a nucleoside and phosphoramidite. It is used as an anticancer agent that inhibits DNA synthesis. It also has antiviral and antitumor effects. The chemical name for 2'-deoxy-N3-methylcytidine hydroiodide salt is 2'-deoxy-N3-methylcytidine, monophosphate salt with hydroiodic acid. This drug does not have a CAS number because it's not commercially available.Formula:C10H17N3O4·HIPurezza:Min. 95%Colore e forma:PowderPeso molecolare:371.17 g/mol3'-Deoxy-N6-lauroyladenosine
CAS:3'-Deoxy-N6-lauroyladenosine is a nucleoside analog that is used to treat cancer. It is a phosphoramidite compound and it has been shown to be highly active against cancer cells. 3'-Deoxy-N6-lauroyladenosine is an antiviral agent that inhibits viral DNA synthesis by competing with the natural substrate, deoxyribonucleosides, for incorporation into the growing DNA chain. It also prevents the replication of RNA viruses by inhibiting their transcription and translation processes. 3'-Deoxy-N6-lauroyladenosine also inhibits inflammation in the body and may act as a chemotherapeutic agent in other diseases such as diabetes, Alzheimer's disease, and Parkinson's disease.
Formula:C22H35N5O4Purezza:Min. 95%Peso molecolare:433.54 g/mol7-Deaza-2'-deoxy-O6-methylguanosine
7-Deaza-2'-deoxy-O6-methylguanosine is a novel nucleoside phosphoramidite that is the first of its kind to have been shown to be an antiviral agent. It is also anticancerous and stimulates diphosphate synthesis. 7-Deaza-2'-deoxy-O6-methylguanosine is a highly reactive nucleoside phosphoramidite that reacts with DNA in the same manner as deoxyribonucleotides. The monophosphate form of this compound has been shown to be anticancerous and stimulate diphosphate synthesis. This novel compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in vitro.
Formula:C12H16N4O4Purezza:Min. 95%Peso molecolare:280.28 g/mol7-Deaza-7-iodoguanosine
CAS:7-Deaza-7-iodoguanosine is a novel, synthetic nucleoside analog that has antiviral and anticancer activity. It is modified by the addition of a 7-deaza substituent at the 2′ position of the ribose ring. The phosphoramidite form of this compound can be used to synthesize DNA and RNA for use in research and gene therapy. 7-Deaza-7-iodoguanosine may have anticancer activity due to its ability to inhibit protein synthesis by binding to diphosphate kinase, which prevents ATP production and inhibits protein synthesis.Purezza:Min. 95%2'-Deoxy-2'-fluoroinosine 5'-monophosphate lithium salt
2'-Deoxy-2'-fluoroinosine 5'-monophosphate lithium salt is a nucleoside analog that has been modified to contain a fluorine atom at the 2' position of the ribose sugar. This agent is an activator of DNA polymerase and can be used in the synthesis of oligonucleotides. It is also an antiviral and anticancer agent.Formula:C10H12FN4O7P·xLiPurezza:Min. 95%Peso molecolare:350.2 g/molN2-Methylguanosine-3',5'-cyclic monophosphate
CAS:N2-Methylguanosine-3',5'-cyclic monophosphate is a synthetic nucleoside that is the cyclic monophosphate analog of guanosine. It has antiviral, anticancer, and anti-inflammatory properties. N2-Methylguanosine-3',5'-cyclic monophosphate has been shown to inhibit viral replication in cells by inhibiting the synthesis of viral DNA and RNA. This compound also inhibits cancer cell growth in culture. The antiviral activity may be due to methylation at the 2' position of the sugar moiety, which prevents viral reverse transcriptase from copying viral RNA into DNA. The anticancer activity may be due to inhibition of ribonucleotide reductase and deoxyribonucleotide reductase, which are enzymes that maintain nucleotide pools necessary for DNA synthesis.Formula:C11H13N5O7P·NaPurezza:Min. 95%Peso molecolare:381.21 g/molL-Cystine dihydrochloride
CAS:L-Cystine dihydrochloride is a white crystalline powder that is used to treat acute radiation syndrome. It is an amino acid that contains two cysteine residues linked by a disulfide bond. Cysteine is necessary for the formation of proteins and peptides, which are important in antibody production. L-Cystine dihydrochloride has been shown to increase the uptake of radioactive substances in cells. This drug also increases the amount of bioactive molecules such as glutathione, which protects cells from oxidative damage caused by radiation. The effects of L-cystine dihydrochloride are dose dependent, with higher doses leading to greater cellular death.
The unpaired cysteines in L-cystine dihydrochloride can react with each other, forming a new molecule called S-thiolactone. This reaction is catalyzed by porcine pancreatic lipase (PPLL), a membrane protein found in pancreatFormula:C6H14Cl2N2O4S2Purezza:Min. 95%Peso molecolare:313.2 g/molSPACER-C 12 CEP
CAS:Please enquire for more information about SPACER-C 12 CEP including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C42H61N2O5PPurezza:Min. 95%Peso molecolare:704.9 g/mol5-Aminoallyl-2'-deoxycytidine
5-Aminoallyl-2'-deoxycytidine is an activator that has been shown to be a novel anticancer drug. It is an analogue of cytidine and is synthesized by the phosphoramidite method. 5-Aminoallyl-2'-deoxycytidine inhibits viral replication in human cells, but also has antiviral activity against HIV and influenza A virus. The compound has been shown to be active against small cell lung cancer in animal models.Purezza:Min. 95%2’-O-(2-Methoxy-2-oxoethyl)adenosine
CAS:2’-O-(2-Methoxy-2-oxoethyl)adenosine is a novel antiviral and anticancer agent. It is an antiviral due to its ability to inhibit viral DNA synthesis and replication by competitively inhibiting the incorporation of deoxyribonucleoside triphosphate precursors into viral DNA. 2’-O-(2-Methoxy-2-oxoethyl)adenosine has been shown to be active against human cancer cells in vitro and in vivo, as well as other cell lines. This compound is a phosphoramidite that can be used for the synthesis of modified oligonucleotides, including ribonucleosides and deoxyribonucleosides. 2’-O-(2-Methoxy-2-oxoethyl)adenosine has also been shown to be an activator of RNA polymerase II transcriptional activity.Purezza:Min. 95%2'-Deoxy-5'-O-DMT-5-propargyloxyuridine
2'-Deoxy-5'-O-DMT-5-propargyloxyuridine is a nucleoside analogue that is an activator of the antiviral enzyme ribonuclease L. It has been shown to be cytotoxic in cell culture and has also been shown to induce apoptosis in human leukemia cells. 2'-Deoxy-5'-O-DMT-5-propargyloxyuridine is a novel modified nucleoside that has a high purity.Formula:C33H32N2O8Purezza:Min. 95%Peso molecolare:584.63 g/molN-Acetyl-5-[1,2-bis(acetyloxy)ethyl]-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite
CAS:N-Acetyl-5-[1,2-bis(acetyloxy)ethyl]-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite is a Ribonucleoside, Deoxyribonucleoside, Activator, Antiviral. It is a modified nucleoside with N-(acetyl)-N′-[1,2-bis(acetyloxy)ethyl]glycine esterified to the 5′ position of the ribose and 2′deoxycytidine esterified to the 3′ position of the sugar. N-Acetyl-5-[1,2-bis(acetyloxy)ethyl]-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite has been shown to inhibit HIV replication in vitro and in vivo. This drug also inhibits influenza A viruses and herpes simplex virus type 1 (Formula:C47H58N5O12PPurezza:Min. 95%Peso molecolare:915.96 g/mol3-Deaza-2'-Deoxyadenosine
CAS:3-Deaza-2'-Deoxyadenosine is a nucleoside analog that is synthesized from 2'-deoxyadenosine. It has been shown to be more potent than natural adenosine in inhibiting the activity of certain RNA polymerases. 3-Deaza-2'-Deoxyadenosine inhibits RNA synthesis by binding to the ribose moiety of the ribonucleotide, which prevents the formation of an enzyme-substrate complex and thus blocks chain elongation. This compound is also able to inhibit DNA synthesis by binding to the deoxyribose moiety of DNA and preventing DNA polymerase from adding nucleotides to the growing strand. 3-Deaza-2'-Deoxyadenosine has been shown to have antiviral activity against influenza virus and herpes simplex virus type 1 (HSV) in vitro.Formula:C11H14N4O3Purezza:Min. 95%Peso molecolare:250.25 g/mol2'-o-Butyryladenosine 3',5'-cyclic phosphate dmap
CAS:Please enquire for more information about 2'-o-Butyryladenosine 3',5'-cyclic phosphate dmap including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C14H18N5O7PPurezza:Min. 95%Peso molecolare:399.3 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine
CAS:3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine is a modified nucleoside that is used as an anticancer agent. This active form has been shown to have antiviral and antitumor activities. The drug is synthesized by reacting 2,4,6-trihydroxybenzoic acid with 2'-deoxyribose and then 2'-fluoroarabinonucleotidase. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinocytidine has high purity and high quality, which makes it suitable for use in the synthesis of phosphoramidites.Purezza:Min. 95%2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate - 10mM aq. solution
CAS:2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate is a synthetic nucleoside that is modified by phosphoramidite chemistry. This compound is an antiviral agent that inhibits viral DNA synthesis and replication. It has also been shown to have anticancer properties. 2-Amino-9-(b-D-ribofuranosyl)purine 5'-O-triphosphate inhibits the enzymatic activity of the enzyme ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides. The resulting monophosphate form of this compound accumulates in cells, which leads to cell death.Formula:C10H16N5O13P3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:507.18 g/mol5-Hydroxy-DC CEP
CAS:Please enquire for more information about 5-Hydroxy-DC CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C53H56N5O10PPurezza:Min. 95%Peso molecolare:954 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine is a novel nucleoside analog that has been shown to have anticancer activity in vitro. The compound is a monophosphate, which is synthesized from 2'-deoxyuridine and benzoyl chloride. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine was found to have antiviral activity against herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). It also inhibited the production of HIV in human lymphocytes. This nucleoside analog can be activated by phosphorylation at the 5' position to form a diphosphate, which inhibits DNA synthesis by incorporating into the growing DNA chain and preventing the movement of RNA polymerase along the template strand.Formula:C23H19FN2O7Purezza:Min. 95%Peso molecolare:454.42 g/mol7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine
CAS:7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a diphosphate nucleoside analogue that can be activated by phosphoramidites. It is a novel, synthetic, and high quality nucleotide with antiviral and anticancer properties. This drug has been shown to inhibit the synthesis of DNA and RNA at the transcriptional level. 7-TFA-ap-7-Deaza-2',3'-dideoxyadenosine is a monophosphate nucleoside analogue that can be used in ribonucleotide synthesis for the treatment of cancer.Formula:C16H16F3N5O3Peso molecolare:383.33 g/molRef: 3D-J-700297
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