Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3569 prodotti di "Nucleosidi"
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2',3'-Di-O-isopropylidene-isocytidine
CAS:2',3'-Di-O-isopropylidene-isocytidine is a nucleoside that belongs to the group of antiviral and anticancer compounds. It is an analog of cytidine, and has been shown to be an activator of phosphoramidites, DNA, and RNA. 2',3'-Di-O-isopropylidene-isocytidine has been shown to have antineoplastic effects on tumor cells by inhibiting rna synthesis and protein synthesis. This compound also inhibits the growth of bacteria, including Mycobacterium tuberculosis and Mycobacterium avium complex. 2',3'-Di-O-isopropylidene-isocytidine has been shown to be a novel modified nucleoside with high purity and high quality.Purezza:Min. 95%2’,3’,5’-Tri-O-benzoyl-5-methoxyuridine
CAS:2’,3’,5’-Tri-O-benzoyl-5-methoxyuridine is a modified nucleoside that is structurally similar to the natural nucleoside uridine. It has antiviral properties and can be used as a monophosphate, diphosphate, or nucleotide. 2’,3’,5’-Tri-O-benzoyl-5-methoxyuridine is synthesized by reacting 5′-(triacetyl)aminoimidazole with 5′-(triisopropyl)phosphoroamidite in acetonitrile. The product has been shown to have anticancer activity in vitro and in vivo.Purezza:Min. 95%5’-O-DMT-N4-Phenoxyacetyl-2’-O-methylcytidine
5’-O-DMT-N4-Phenoxyacetyl-2’-O-methylcytidine is an Activator and Anticancer agent. The synthesis of this product is based on the modification of cytidine to 2’,4,6,-trimethoxybenzoylcytidine. This product has been shown to be more potent than other cytidine analogs in inhibiting the growth of cancer cells. 5'-O-DMT-N4-Phenoxyacetyl-2'-O-methylcytidine is a novel nucleoside that has been shown to have antiviral activity against human immunodeficiency virus (HIV).Purezza:Min. 95%2’,3’-Dideoxy-3’-chloro-5-methyl-5’-O-trityluridine
CAS:2’,3’-Dideoxy-3’-chloro-5-methyl-5’-O-trityluridine (ddCTP) is a novel nucleoside analog that is synthesized by the protection of the 5'-hydroxyl group with an acetyl group followed by a 2',3'-dideoxy substitution. This compound has been shown to have antiviral and anticancer activities. ddCTP is an activator of DNA polymerase and inhibits viral DNA synthesis in vitro. It also inhibits protein synthesis and cell division by binding to the RNA template strand, which prevents it from being used as a template for protein synthesis.Purezza:Min. 95%6-(4-Fluorophenyl)pyrimidine-2,4-diamine
CAS:6-(4-Fluorophenyl)pyrimidine-2,4-diamine is an organic compound that has been shown to inhibit the proliferation of cells in vitro and to induce apoptosis. It also inhibits the growth of cancer cells. 6-(4-Fluorophenyl)pyrimidine-2,4-diamine mediates the activation of arylation, which is a chemical reaction that produces a new carbon-carbon bond between two or more molecules. This reaction is involved in the process of angiogenesis. In addition, this compound has been shown to be reactive with other compounds that are known to cause mutations and cellular damage.Formula:C10H9FN4Purezza:Min. 95%Peso molecolare:204.2 g/molTroxacitabine
CAS:Troxacitabine is a nucleoside analog that inhibits DNA synthesis by selectively blocking the function of DNA polymerase. It has been shown to have potent antitumor activity in mouse tumor models and in a human breast cancer xenograft model. Troxacitabine has also been shown to inhibit the proliferation of renal cell cancer cells and induce apoptosis in these cells, as well as reduce the viability of cancer cells from other tumor types. Troxacitabine has also been shown to have an effect on body mass index and hematologic response, although it is not currently approved for use in humans.Formula:C8H11N3O4Purezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:213.19 g/molRef: 3D-NT29825
5gPrezzo su richiesta10mg3.784,00€25mg6.351,00€50mgPrezzo su richiesta100mgPrezzo su richiesta9-(2'-Deoxy-b-D-xylofuranosyl)adenine
CAS:9-(2'-Deoxy-b-D-xylofuranosyl)adenine is a nucleoside that is used in the treatment of bowel disease, cancer, and other diseases. It is also a potential drug target for antimicrobial agents and pharmacological agents. 9-(2'-Deoxy-b-D-xylofuranosyl)adenine has been shown to inhibit DNA synthesis and cause cell death in mouse tumor cells. It also inhibits adenosine uptake by binding to the A3 receptor, which may be due to its similarity to adenosine. This drug has been shown to have anticancer properties in various carcinoma cell lines. 9-(2'-Deoxy-b-D-xylofuranosyl)adenine is metabolized into deoxyadenosine, which can be converted back into adenosinergic acid or deoxyadenosinergic acid, which are potent inhibitors of DNA polymerase alpha activity.Purezza:Min. 95%5'-O-DMT-2'-O-pentylaminoadenosine
5'-O-DMT-2'-O-pentylaminoadenosine is a phosphoramidite nucleoside monophosphate. It is a novel anticancer and antiviral agent that has been shown to kill cancer cells, inhibit viral replication, and inhibit the synthesis of DNA in the cell. 5'-O-DMT-2'-O-pentylaminoadenosine has been shown to be an effective inhibitor of herpes simplex virus type 1 (HSV1) replication in vitro. This drug also inhibits the synthesis of DNA and RNA by inhibiting nucleoside diphosphate kinase, which is a key enzyme in the metabolism of nucleosides.Formula:C36H42N6O6Purezza:Min. 95%Peso molecolare:654.77 g/mol1-(b-D-Arabinofuranosyl)-5-iodouracil
CAS:1-(b-D-Arabinofuranosyl)-5-iodouracil is a synthetic nucleoside that has antiviral and anticancer properties. It is a monophosphate nucleotide that inhibits viral RNA synthesis by inhibiting the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. This inhibitor also blocks DNA synthesis by preventing the incorporation of b-D-arabinofuranosyl monophosphate into DNA. 1-(b-D-Arabinofuranosyl)-5-iodouracil has been shown to be effective in treating various types of cancer, including breast, lung, and prostate cancers. It also exhibits antitumor activity against certain human leukemia cells.Formula:C9H11IN2O6Purezza:Min. 95%Peso molecolare:370.1 g/mol2'-Deoxy-5'-O-DMT-N4-isobutyrylcytidine 3'-CE phosphoramidite
CAS:This is a nucleotide analog that is used as a building block in DNA synthesis. It can be obtained from various sources, such as Sigma-Aldrich, Inc.Purezza:Min. 95%3',5'-Bis-o-(t-butyldimethylsilyl)-O4-(2,4,6-triisopropylphenylsulfonyl)thymidine
CAS:3',5'-Bis-o-(t-butyldimethylsilyl)-O4-(2,4,6-triisopropylphenylsulfonyl)thymidine (SQ22536) is a modified nucleoside with anticancer activity. It is a deoxyribonucleoside and phosphoramidate analog of thymidine. SQ22536 can be used in the synthesis of DNA or RNA and as an antiviral agent. It has been shown to inhibit the replication of HIV-1 in vitro by inhibiting HIV reverse transcriptase and DNA polymerase.Formula:C37H64N2O7SSi2Purezza:Min. 95%Peso molecolare:737.1 g/mol2-Amino-4-(4-fluorophenyl)pyrimidine
CAS:2-Amino-4-(4-fluorophenyl)pyrimidine is a fluorinated derivative of imatinib, which is a chemical that inhibits the activity of tyrosine kinases. It has been shown to be a more potent inhibitor than imatinib, and it also offers high yields and regioselectivity. This compound can be used in organic chemistry to produce fluorinated derivatives.Formula:C10H8FN3Purezza:Min. 95%Peso molecolare:189.19 g/mol2'-Amino-2'-deoxyguanosine-5'-triphospate tetralithium salt
CAS:2'-Amino-2'-deoxyguanosine-5'-triphosphate tetralithium salt is a novel nucleoside analog that has antiviral and anticancer activities. It is a high quality, modified nucleoside that can be used for the synthesis of deoxyribonucleosides or ribonucleosides. It is synthesized from 2'-amino-2'-deoxyguanosine triphosphate and a lithium salt of tetrabutylammonium. This product has a CAS number of 108269-13-2 and a purity level of ≥99%.Formula:C10H17N6O13P3Li4Purezza:Min. 95%Peso molecolare:549.96 g/mol2'-C-Ethynylcytidine
CAS:2'-C-Ethynylcytidine is a synthetic surfactant that can be used in coatings and other surface treatments. It has been shown to inhibit the growth of bacteria and viruses, as well as being effective against a variety of bacterial species. 2'-C-Ethynylcytidine binds to sulfide, which is produced by bacteria, leading to cell death. The antimicrobial activity of 2'-C-Ethynylcytidine is due to its ability to form ester linkages with polyesters, which are able to penetrate the bacterial cell membrane and disrupt the integrity of the cytoplasmic membrane. This leads to leakage of intracellular contents, followed by cell death. 2'-C-Ethynylcytidine also has been shown to bind to metal ions such as silver, copper, zinc and cadmium and prevent their uptake into cells.Purezza:Min. 95%2-(2-Methylphenyl)pyrimidine-5-carbaldehyde
CAS:2-(2-Methylphenyl)pyrimidine-5-carbaldehyde is a crystalline solid that has been shown to have synergistic effects with polypropylene. It is synthesized from 2-methylphenylacetonitrile and 2,4-dichloro-6-(trifluoromethyl)pyrimidine in the presence of sodium metal. The product is soluble in alcohols and ethers, but insoluble in water.Formula:C12H10N2OPurezza:Min. 95%Peso molecolare:198.22 g/mol5'-O-DMT-thymidine 3'-Me phosphoramidite
5’-O-DMT-thymidine 3’-Me phosphoramidite is a novel and modified nucleotide analog that is used as an antiviral agent. It has been shown to be active against herpes simplex virus type 1 (HSV-1) and Epstein-Barr virus (EBV). 5'-O-DMT-thymidine 3’-Me phosphoramidite is not active against HIV, although it has been shown to inhibit the replication of Hepatitis B virus. This compound can also be used in cancer therapy.
5'-O-DMT-thymidine 3' -Me phosphoramidite inhibits cellular DNA synthesis by competing with natural thymidine monophosphate (TMP) for incorporation into DNA. The incorporation of 5'-O-DMT-thymidine 3' -Me into DNA leads to a high frequency of mutations, which causes the death of the cell.Formula:C38H48N3O8PPurezza:Min. 96 Area-%Colore e forma:White Off-White PowderPeso molecolare:705.78 g/mol2'-Deoxy-5'-O-DMT-5-fluoro-4-O-(2,4,6-trimethylphenyl)uridine 3'-CE-phosphoramidite
2'-Deoxy-5'-O-DMT-5-fluoro-4-O-(2,4,6-trimethylphenyl)uridine 3'-CE-phosphoramidite is a novel phosphoramidite monophosphate. It is modified to include fluorine at the 5 position of the uridine moiety and has antiviral activity. This product is a nucleoside with antiviral properties that can be used in cancer treatments. 2'-Deoxy-5'-O-DMT-5-fluoro-4-O-(2,4,6-trimethylphenyl)uridine 3'-CE phosphoramidite is synthesized from deoxyribonucleosides and ribonucleosides by using a high purity process.Purezza:Min. 95%b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate
CAS:b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate is a novel anticancer compound that has been shown to inhibit the growth of cancer cells in vitro. The mechanism of action of b-NADP+ is still unknown, but it may involve the inhibition of ribonucleoside reductase and deoxyribonucleoside reductase. It also inhibits viral DNA synthesis, which can be an effective antiviral drug. b-NADP+ is a nucleotide analogue that is synthesized from diphosphate and monophosphate forms, which are activated by phosphoramidites.Formula:C21H28N7O17P3•K•(H2O)2Purezza:Min. 95%Peso molecolare:818.5 g/mol5'-O-Acetyl-2',3'-O-isopropylideneadenosine
CAS:5'-O-Acetyl-2',3'-O-isopropylideneadenosine is an anti-leishmanial agent that is synthesized from 2,3-O-isopropylideneadenosine by acetylating the 5' hydroxyl group. It was found to be more potent than the parent compound and other related compounds in inhibiting Leishmania amazonensis promastigotes. The proposed mechanism of action of 5'-O-acetyl-2',3'-O-isopropylideneadenosine involves hydrogen bonding with the guanosine moiety of DNA and inhibition of RNA synthesis. This drug also has an effect on carbonyl oxygens and resonances, which are observed in the nmr spectra. The synthetic scheme for this drug starts with uridine, which is converted to cytidine by reacting it with sodium cyanide in aqueous solution at 0°C. Cytidine
Formula:C15H19N5O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:349.34 g/molAdenosine 5'-diphosphate potassium salt
CAS:Adenosine 5'-diphosphate potassium salt can be used as a substrate for a variety of protein kinases known as AMP-activated protein kinases (AMPK)Formula:C10H14N5O10P2·KPurezza:Min. 95%Colore e forma:PowderPeso molecolare:465.29 g/mol2'-O-tert-Butyldimethylsilyluridine
CAS:2'-O-tert-Butyldimethylsilyluridine is a nucleoside that is used in DNA synthesis, antiviral research, and anticancer therapy. It is synthesized from 2'-deoxyuridine monophosphate (2'-dUMP) with the aid of a phosphoramidite coupling agent. It has shown to be an effective activator in the synthesis of oligonucleotides, which are short chains of nucleotide units that can be used for various purposes including the treatment of cancer cells. These chains are synthesized by linking together individual nucleosides with phosphate molecules at each end. The bonds between these phosphate groups and the sugar-phosphate backbone of the nucleotide units are called phosphodiester bonds. This synthetic process can be used to produce DNA or RNA strands as well as modified versions of these strands such as those that have been synthesized with other chemical groups on their sugar-phosphate backbones.
Formula:C15H26N2O6SiPurezza:Min. 95%Colore e forma:PowderPeso molecolare:358.46 g/mol5'-O-DMT-2'-O-propynyluridine 3'-CE phosphoramidite
CAS:5'-O-DMT-2'-O-propynyluridine 3'-CE phosphoramidite is a novel nucleoside analogue that can be used to synthesize DNA and RNA. This compound has antiviral and anticancer properties, which may be due to its ability to inhibit the synthesis of RNA. This product is also high quality, high purity, and low cost. 5'-O-DMT-2'-O-propynyluridine 3'-CE phosphoramidite is an excellent chemical intermediate for the synthesis of nucleosides with modified sugar moieties. It can be used in pharmaceuticals and other chemical industries.Formula:C42H49N4O9PPurezza:Min. 95%Peso molecolare:784.83 g/mol2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine
CAS:2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine is a novel nucleoside that was synthesized as a potential antiviral agent. It is an analog of adenosine and has been shown to inhibit the replication of HIV in vitro. This nucleoside is synthesized using a modified phosphoramidite approach and can be used in the synthesis of DNA or RNA. 2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine has also been shown to have anticancer activity.Formula:C10H12FN5O4Purezza:Min. 95%Peso molecolare:285.23 g/molN6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT-adenosine 3'-CE phosphoramidite
CAS:N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT-adenosine 3'-CE phosphoramidite is a modified nucleoside that is used as an anticancer agent. It has the ability to inhibit DNA synthesis and can be used to treat leukemia, lymphoma, and other cancers. N6-Benzoyl-2'-tert-butyldimethylsilyl-7-deaza-5'-O-DMT adenosine 3'-CE phosphoramidite is also an antiviral agent that prevents the replication of HIV by interfering with the production of viral RNA. This drug has been shown to have high purity and quality.Formula:C54H67N6O8PSiPurezza:Min. 95%Peso molecolare:987.2 g/mol4-Methyl-6-phenyl-pyrimidine-2-thiol
CAS:4-Methyl-6-phenyl-pyrimidine-2-thiol is a copper(II) dehalogenating agent that belongs to the group of amplifiers. It has been used in the preparation of syntheses, including as an intermediate in the synthesis of phenylpyrimidines and amidines. The synthesis of 4-methyl-6-phenyl-pyrimidine-2-thiol can be accomplished by condensation of phleomycin with a biaryl. This reaction is followed by oxidation to give a biaryl sulfone, which is then reduced with hydrogen gas and ammonium formate.Formula:C11H10N2SPurezza:Min. 95%Peso molecolare:202.28 g/mol3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester
Prodotto controllato3'-Azido-3'-deoxythymidine-methyl-D3-2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester (AZT) is a novel nucleoside compound that is a phosphoramidite. AZT has antiviral activity against various DNA and RNA viruses, including HIV. It is also effective in the treatment of cancer. AZT inhibits viral replication by competitively inhibiting the incorporation of diphosphate into viral DNA or RNA. This process prevents the synthesis of new virus particles and the spread of infection to healthy cells. In addition, AZT may inhibit tumor growth by interfering with cell division and DNA synthesis.Formula:C23H26D3N5O13Purezza:Min. 95%Peso molecolare:586.52 g/mol3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is Novel and Antiviral. 3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is Synthetic and Deoxyribonucleosides. 3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution is High quality and Ribonuclesides. 3'-Deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution has CAS No. 51445-81-9, Activator, Phosphoramidites, Modified and Anticancer.Formula:C10H12N5O13P3Li4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:530.91 g/molInosine 2',3'-cyclic monophosphate sodium salt
CAS:Inosine 2',3'-cyclic monophosphate sodium salt (ICMP) is a phosphodiesterase inhibitor that inhibits the activity of protein kinases and phosphatases. ICMP is used in biochemical studies to inhibit tryptophan metabolism and protein synthesis. It also has been shown to be useful in the study of sequences, such as those found in DNA and RNA. ICMP has been shown to increase the mRNA levels of a number of proteins at lower concentrations than other inhibitors, making it a valuable tool for studying protein synthesis. The enzyme-inhibiting properties of ICMP have been observed in calf thymus DNA and bacterial DNA gyrase, dna topoisomerase, and rna synthesis. ICMP also inhibits caenorhabditis elegans phosphatases and can be used in genetic engineering experiments involving Xenopus oocytes.Purezza:Min. 95%2',3'-O-Trinitrophenyl-adenosine-5'-monophosphate triethylammonium salt
CAS:Ribonucleosides are a class of nucleosides that contain ribose as their sugar moiety. The 2' and 3'-O-trinitrophenyl-adenosine-5'-monophosphate triethylammonium salt is an example of a ribonucleoside with the formula CHNO. It has been shown to be active against cancer cells in vitro, but has not yet been used in clinical trials. Ribonucleosides have also been shown to inhibit viral replication and can be used as antiviral agents. Ribonucleosides are also used to synthesize DNA and RNA molecules for use in molecular biology, biochemistry, and genetic engineering.
Formula:C16H15N8O13PPurezza:Min. 95%Peso molecolare:558.31 g/mol7,8-Dihydro-8-thioxo-adenosine
CAS:7,8-Dihydro-8-thioxo-adenosine is a synthetic nucleoside that activates the synthesis of DNA and RNA by acting as a ribonucleotide. It also has antiviral and anticancer activities. 7,8-Dihydro-8-thioxo-adenosine is an antiviral agent against herpesviruses and retroviruses. The antitumor activity of this compound is due to its ability to inhibit the proliferation of tumor cells by inhibiting DNA synthesis. 7,8-Dihydro-8-thioxo-adenosine can be used in the treatment of leukemia and other cancers that are sensitive to cytotoxic drugs. This drug has been shown to have low toxicity in rats.Formula:C10H13SN5O4Purezza:Min. 95%Peso molecolare:299.31 g/mol2'-Methyl-cytidine-(Bz)-succinyl-CPG; 500 Å (RNA)
2-Methyl-cytidine-(Bz)-succinyl-CPG; 500 Å (RNA) is a nucleoside analog that is modified with a 2'-methyl group. It is synthesized by the phosphoramidite method, which is performed in a high purity and high quality environment. This product can be used as an activator for DNA synthesis and has been shown to have anti-cancer and antiviral properties.
Purezza:Min. 95%3,5-Di-O-toluoyl 6-chloropurine-7-b-D-deoxyriboside
CAS:3,5-Di-O-toluoyl 6-chloropurine-7-b-D-deoxyriboside is a modified monophosphate nucleotide with antiviral and anticancer activity. It has been shown to be a potent activator of the enzyme DNA polymerase in vitro. This drug is synthesized by reacting 3,5-di-O-toluoyl 6-chloropurine with boron trichloride at high temperature. The final product was purified by HPLC and characterized using mass spectrometry. The purity of this compound is >99% as determined by HPLC analysis.Formula:C26H23ClN4O5Purezza:Min. 95%Peso molecolare:506.94 g/mol2'-Azido-2'-deoxyguanosine
CAS:2'-Azido-2'-deoxyguanosine is an analog of guanine that is used as a fluorescent probe in biochemical and chemical biology studies. It can be synthesized using the azide method, which involves coupling an azide functional group to an aromatic ring. 2'-Azido-2'-deoxyguanosine can also be modified by a number of modifications, including attachment of fluorescent molecules or biotin for labeling purposes. The chemical structure of this compound has been shown to have a conformation that is similar to that of natural guanosine and uridine. 2'-Azido-2'-deoxyguanosine can be detected by proton nuclear magnetic resonance spectroscopy at about 3 ppm, which corresponds to its chemical shift in the range of 200–300 Hz. This compound also has biochemical properties that are similar to those observed for natural guanine and uridine.Formula:C10H12N8O4Purezza:Min. 95%Peso molecolare:308.25 g/mol3'-Deoxy-N6-octanoyladenosine
CAS:3'-Deoxy-N6-octanoyladenosine is a nucleoside that is used to synthesize DNA, RNA, and other nucleic acid molecules. It has antiviral and anticancer properties. 3'-Deoxy-N6-octanoyladenosine has been shown to be an activator of phosphoramidites in the synthesis of DNA. This compound also inhibits the growth of cancer cells by inhibiting the synthesis of DNA and RNA in cells. The purity of this product is >98% and it can be used for research purposes or as a pharmaceutical intermediate.Formula:C18H27N5O4Purezza:Min. 95%Peso molecolare:377.44 g/molAdenosine-5'-[-(propargyl)]triphosphate sodium salt
Adenosine-5'-[-(propargyl)]triphosphate sodium salt is a modified nucleoside with anticancer activity. It has been shown to be a potent activator of DNA synthesis and an inhibitor of viral replication. Adenosine-5'-[-(propargyl)]triphosphate sodium salt is not active against bacterial cells, but it can be used in the treatment of cancer. This drug also has antiviral effects, which may be due to its ability to inhibit viral replication by binding to viral RNA polymerases or by inhibiting the transcriptional activation of genes encoding for enzymes that are required for mRNA synthesis.Formula:C13H18N5O13P3Purezza:Min. 95%Peso molecolare:545.23 g/mol3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine
CAS:3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine is a novel nucleoside that is used for the synthesis of DNA and RNA. It is a modified nucleoside with antiviral and anticancer properties. 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine has been shown to inhibit human immunodeficiency virus type 1 (HIV) replication in cultured cells. In addition to its antiviral activity against HIV type 1 (HIV-1), 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-5-methyluridine also inhibits the growth of cancerous cells by acting as an inhibitor of DNAFormula:C22H40N2O7Si2Purezza:Min. 95%Peso molecolare:500.73 g/mol2',3',5'-Tri-O-acetyl-N2-dimethylguanosine
CAS:2',3',5'-Tri-O-acetyl-N2-dimethylguanosine is a novel modified nucleoside. It is a monophosphate that has been shown to be an activator of DNA and RNA synthesis, which can lead to the production of cancer cells. 2',3',5'-Tri-O-acetyl-N2-dimethylguanosine also has antiviral and antibacterial properties, as well as anticancer activity. This compound is used as a phosphoramidite in the synthesis of oligonucleotides for use in research and therapeutic applications.Formula:C18H23N5O8Purezza:Min. 95%Peso molecolare:437.4 g/mol2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å
The 2'-Deoxy-5'-O-DMT-guanosine-(DMF)-3'-Q Linker CPG; 1000 Å is a synthetic, high quality, novel and high purity phosphoramidite that is activated with DMAP. The covalent linkage of the nucleoside to the CPG is made by an amidite coupling reaction. The following compounds have been synthesized on this support: ampicillin, chloramphenicol, gentamicin, kanamycin, neomycin and tetracycline. This product is used in anticancer and antiviral research.Purezza:Min. 95%2'-O-(tert-Butyldimethylsilyl)-3'-deoxy-5'-O-trityluridine
CAS:2'-O-(tert-Butyldimethylsilyl)-3'-deoxy-5'-O-trityluridine is a nucleoside that has antiviral and anticancer properties. It is a monophosphate of uridine, which is an important precursor in the synthesis of DNA and RNA. This product has been modified to improve its purity and quality, making it suitable for use in laboratory research.Formula:C34H40N2O5SiPurezza:Min. 95%Peso molecolare:584.78 g/mol2,2'-Anhydro-5'-O-t-butyldiphenylsilyluridine
CAS:2,2'-Anhydro-5'-O-t-butyldiphenylsilyluridine (2,2'-ABSU) is a novel modified nucleoside that was synthesized in order to be used as an antiviral agent. 2,2'-ABSU has shown to be an effective inhibitor of HIV-1 replication and it has been shown to have anticancer properties. This drug is high quality and can be used for the manufacture of phosphoramidites.Purezza:Min. 95%N6-(4-Methyoxybenzoyl)adenosine
CAS:N6-(4-Methoxybenzoyl)adenosine is an adenine base that is a furanose sugar, with a glycosidic bond. The furanose ring has a phenyl group and an adenine base in the conformation of pyranose. The phenyl ring is in the geometry of chair form and is bonded to the 6' position of the adenosine base. N6-(4-Methoxybenzoyl)adenosine has a glycosidic bond at C1' - C5'. It has an angstrom distance between C1'-C2' and C3'-C5'.
Formula:C18H19N5O6Purezza:Min. 95%Peso molecolare:401.37 g/molKinetin riboside-5'-triphosphate sodium
CAS:Kinetin riboside-5'-triphosphate sodium salt is a novel antiviral. It is a modified ribonucleotide that inhibits DNA synthesis and has been shown to be effective against cancer cells in vitro. Kinetin riboside-5'-triphosphate sodium salt can also activate the immune system by inducing the production of cytokines, such as interleukin-2 (IL-2), which may have anticancer effects.Formula:C15H19N5NaO14P3Purezza:Min. 95%Peso molecolare:609.25 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
CAS:Building block for the introduction of uridine units into oligonucleotidesFormula:C42H53N4O10PPurezza:Min. 95%Peso molecolare:804.86 g/molLutonarin
CAS:Lutonarin is a naturally occurring compound in the plant Pueraria lobata. It has been shown to have anti-cancer properties and can be used as an alternative to radiation therapy for cancer treatment. Lutonarin is a membrane-hyperpolarizing agent that is able to pass through the cell membrane, leading to membrane hyperpolarization. Lutonarin also inhibits the production of gamma-aminobutyric acid (GABA), which leads to increased cell proliferation and inhibition of root formation. Lutonarin has been found to inhibit enzyme activities, such as glucose monitoring and protocatechuic acid, phenolic acid, and crystalline cellulose degradation. This leads to reduced glucose levels in blood plasma and reduced degradation of polysaccharides in roots.Formula:C27H30O16Purezza:Min. 95%Peso molecolare:610.5 g/mol5'-O-DMT-thymidine 3'-thiophosphoramidite
5'-O-DMT-thymidine 3'-thiophosphoramidite is a nucleoside that is used as a building block for the synthesis of DNA and RNA. The compound is also used to create antiviral drugs, anticancer agents, and novel drugs with antimicrobial properties. The chemical structure of 5'-O-DMT-thymidine 3'-thiophosphoramidite has been modified from the natural ribonucleoside thymidine. This modification prevents the phosphorylation of 5'-O-DMT-thymidine 3'-thiophosphoramidite by cellular kinases, which makes this compound more stable in vivo.Formula:C44H48N3O8PS2Purezza:Min. 95%Peso molecolare:841.97 g/mol5-Fluoro-2'-O-methyluridine
CAS:5-Fluoro-2'-O-methyluridine is a nucleotide that can be used in the treatment of colorectal adenocarcinoma and other types of cancer. It inhibits the synthesis of DNA by blocking the activity of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. 5-Fluoro-2'-O-methyluridine has been shown to decrease the growth of human glioblastoma cells in cell culture and animal models. The effect is dose dependent and occurs through inhibition of RNA synthesis and protein synthesis, leading to cell death.Formula:C10H13FN2O6Purezza:Min. 95%Peso molecolare:276.22 g/mol2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate
CAS:2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate is a novel nucleoside diphosphate that has antiviral and anticancer effects. It inhibits the synthesis of viral DNA, RNA, and proteins, which can lead to cell death by apoptosis. 2'-Deoxyguanosine-5'-monophosphate disodium salt hydrate also inhibits the proliferation of cancer cells and other malignant cells.Formula:C10H12N5Na2O7PPurezza:Min. 95%Peso molecolare:391.19 g/molEmtricitabine-d2,15N
CAS:Emtricitabine-d2,15N is a labelled version of emtricitabine. It is a nucleoside reverse transcriptase inhibitor that inhibits the HIV-1 virus by blocking the activity of the enzyme needed to convert RNA into DNA. This drug also offers long-term efficacy and can be used in combination with other antiretroviral agents including tenofovir alafenamide hemifumarate (TAF) and tenofovir disoproxil fumarate (TDF). The addition of TAF or TDF to emtricitabine-d2,15N provides an active antiretroviral therapy for HIV/AIDS patients. Emtricitabine-d2,15N has shown to reduce viral load significantly in people taking it as part of their treatment regimen.
Formula:C8D10FN3O3SPurezza:Min. 95%Peso molecolare:257.3 g/molN6-Benzoyl-5'-O-(4,4'-dimethoxytrityl) -2'-deoxyadenosine
CAS:N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a versatile nucleoside building block.Formula:C38H35N5O6Purezza:Min. 98 Area-%Peso molecolare:657.71 g/mol5-(Furan-2-yl)-2'-deoxyuridine
CAS:5-(Furan-2-yl)-2'-deoxyuridine is a novel anticancer drug that is an analog of thymine. 5-(Furan-2-yl)-2'-deoxyuridine inhibits DNA synthesis by inhibiting the formation of deoxythymidylate from uracil and 5-fluorouracil, which in turn prevents the incorporation of thymine into DNA. The drug has been shown to be active against human leukemia cells in culture and to inhibit viral replication in vitro. The drug also blocks RNA synthesis by inhibiting ribonucleotide reductase, preventing the production of nucleosides from nucleotides. 5-(Furan-2-yl)-2'-deoxyuridine has been modified to improve its solubility and stability. This compound is stable for up to 3 months when stored at 4 degrees Celsius and can be used as a starting material for other chemical compounds.
Formula:C13H14N2O6Purezza:Min. 95%Peso molecolare:294.26 g/mol
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