
Nucleosidi
Trovati 3569 prodotti di "Nucleosidi"
4-(4-Fluorophenyl)pyrimidine-2-thiol
CAS:4-(4-Fluorophenyl)pyrimidine-2-thiol is a monophosphate deoxyribonucleoside that has been modified to include an activator group. This modification allows for the phosphoramidite of 4-(4-Fluorophenyl)pyrimidine-2-thiol to be incorporated into DNA, which makes it a novel substance. The CAS number for 4-(4-Fluorophenyl)pyrimidine-2-thiol is 155957-43-0. 4-(4-Fluorophenyl)pyrimidine-2-thiol has shown anticancer activity in vitro and may have potential as a cancer chemotherapeutic agent.Formula:C10H7FN2SPurezza:Min. 95%Peso molecolare:206.24 g/molPyrimidine-5-carboxamidine hydrochloride
CAS:Pyrimidine-5-carboxamidine hydrochloride (GC) is a guanosine analog that inhibits bacterial growth by binding to the anticodon region of ribosomes. GC has been shown to bind to the replicons of many organisms, including bacteria, and inhibit the formation of mRNA from DNA. This drug also inhibits methyltransferase, which prevents transfer RNA from being modified with methionine. GC may be used in research for eukaryotes and deamination reactions in trna modification.Formula:C5H6N4·HClPurezza:Min. 95%Peso molecolare:158.59 g/mol2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine
CAS:2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a novel nucleoside analogue that inhibits the proliferation of cancer cells. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides and thereby prevents viral replication. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine has antiviral activity against influenza A virus and herpes simplex virus type 1 (HSV-1) in cell culture. This drug also has an inhibitory effect on the DNA polymerases and other enzymes involved in DNA synthesis. 2',3',5'-Tri-O-benzoyl-4'-C-fluoroadenosine is a high quality product with high purity, CAS No. 1000203-40-6.Purezza:Min. 95%2,6-Dihydro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS:Prodotto controllato2,6-Dihydro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine is a synthetic activator that is used in the synthesis of nucleosides and nucleotide phosphoramidites. It has been shown to have antiviral activity against herpes simplex virus type 1, herpes simplex virus type 2, and vesicular stomatitis virus.Formula:C16H22N4O7Purezza:Min. 95%Peso molecolare:382.37 g/mol1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil
1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil is a monophosphate nucleotide that is used in antiviral therapy. It inhibits viral DNA synthesis by inhibiting viral DNA polymerase and viral RNA transcription. The drug is currently in phase I clinical trials for the treatment of cancer and AIDS. 1-(2'-Deoxy-2'-fluoro-5'-O-trityl-b-L-arabinofuranosyl)-uracil is a novel compound that has not been described in the literature before. The drug was synthesized by modifying a natural nucleoside, uracil, with fluorine to produce an antiviral agent. This compound has shown anticancer effects in vitro and in vivo experiments as well as antiplasmodial activity against malaria.Formula:C28H25FN2O5Purezza:Min. 95%Peso molecolare:488.51 g/molN6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite
N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite is a novel antiviral agent that exhibits high quality and high purity. It can be used to synthesize DNA, RNA, and other nucleosides. N6-Benzoyl-2'-deoxy-5'-O-levulinoyladenosine-3'-CE phosphoramidite is an activator of the DNA polymerase and an inhibitor of the viral polymerase. This compound has been shown to have anticancer properties in vitro and in vivo.Formula:C31H40N7O7PPurezza:Min. 95%Peso molecolare:653.67 g/molN4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-DMT-2'-ethylfluoro-5-methylcytidine 3'-CE phosphoramidite is a novel, deoxyribonucleosides that has been synthesized with high purity, high quality, and high yield. It is an anticancer drug that inhibits the synthesis of ribonucleotides in DNA and RNA.Purezza:Min. 95%9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite
CAS:9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite is a novel nucleoside analogue that has shown to be effective against cancer. This product can also be used as an antiviral and antifungal agent. It is synthesized from 2,3,4,5,6-pentaacetoxybenzaldehyde and chloroacetamide. 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite is a high quality product that is made of Ribonuclesides, Synthetic Monophosphate Nucleosides Diphosphate Modified Deoxyribonucleosides Activator.Formula:C44H53FN7O8PPurezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:857.93 g/mol4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidine-1-(b-D-ribofuranosyl-5'-triphosphate)
CAS:4-Amino-3-(1-naphthylmethyl)-1H-pyrazolo[3,4-d]pyrimidine-1-(b-D-ribofuranosyl-5'-triphosphate) is a nucleoside that inhibits the growth of cancer cells. It has been shown to inhibit the growth of leukemia and lymphoma cells in vitro. This compound is active against herpes simplex virus type 1 (HSV1) and has antiviral properties. The chemical synthesis of 4-amino-(1HNMPP) is novel and should provide high purity and quality products.
Formula:C21H24N5O13P3Purezza:Min. 95%Peso molecolare:647.36 g/mol7-Deazapurine
CAS:7-Deazapurine is a cytostatic agent that inhibits the polymerase chain reaction by competitive inhibition of the incorporation of nucleotides into DNA. It has potent antitumor activity and significant cytotoxicity, which are due to its ability to inhibit DNA synthesis and cell division. 7-Deazapurine is also a nucleophilic compound that reacts with hydroxyl groups in DNA. The hydrolysis of 7-deazapurine by hydroxylases can be prevented by addition of high salt or trifluoroacetic acid, but this does not seem to affect its cytotoxic effects. 7-Deazapurine has been shown to have significant cytotoxicity against miapaca-2 cells and other cancer cell lines.Formula:C6H5N3Purezza:Min. 95%Peso molecolare:119.12 g/mol8-Aminoguanosine
CAS:8-Aminoguanosine is a synthetic purine nucleoside that inhibits DNA synthesis. It has been shown to inhibit the proliferation of HL-60 cells, which are a model for human monocytes and neutrophils. 8-Aminoguanosine has been shown to bind to the template strand of DNA and inhibit the incorporation of deoxyribonucleotide triphosphates into the newly synthesized strand. This binding prevents DNA replication by preventing access to the template strand of DNA. 8-Aminoguanosine inhibits cyclin D2, an enzyme required for cell division, at concentrations as low as 0.1 mM, and it also inhibits microtubule assembly. 8-Aminoguanosine has shown in vitro activity against various tumor cell lines including Molt-4 and MCF7 cells, and in vivo activity in a mouse model against C3H/HeJ mice transplanted with Lewis lung carcinoma cells.
Formula:C10H14N6O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:298.26 g/mol2-Methylthio-N6-methyladenosine
CAS:2-Methylthio-N6-methyladenosine is an adenosine nucleoside that is found in the DNA of eukaryotes. It is similar to 2-methylthio-n6-isopentenyladenosine, which is a modified form of n6-methyladenosine. The chemical structures of both molecules are related to the thermodynamic properties of the molecule and their ability to be postsynthetically modified. These modifications can lead to changes in their translation, which can have implications for the development and progression of disease. 2-Methylthio-N6-methyladenosine has a role in epigenetics, which is defined as changes in gene expression without any alterations in DNA sequence. In this case, it may modify the chloride ion concentration by changing its chemical structure, leading to epigenetic changes that can affect how genes are expressed or translated into proteins.Formula:C12H17N5O4SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:327.36 g/molN4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite
N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT-b-D-arabinofuranosyl)cytosine 3'-CE phosphoramidite is a novel nucleoside designed for DNA activation. It has high quality and high purity, which are essential for pharmaceutical and analytical applications. This product is used in the synthesis of DNA, antiviral drugs, and anti-cancer agents. N4-Acetyl-1-(2'-O-acetyl-5'-O-DMT b -D -arabinofuranosyl)cytosine 3'-CE phosphoramidite can be used as an activator in the synthesis of deoxyribonucleosides and ribonucleosides.Formula:C22H34N5O8PPurezza:Min. 95%Peso molecolare:527.51 g/mol1-(2',3',5'-Tri-O-acetyl-b-D-arabinofuranosyl)uracil
1-(2',3',5'-Tri-O-acetyl-b-D-arabinofuranosyl)uracil is a novel nucleoside analog with antiviral and anticancer activities. It is a modified nucleoside that is synthesized from 2',3',5'-triacetyl b-D-arabinofuranosyl uracil. The synthesis of this compound involves the use of acetylation, which produces a monophosphate form of the nucleoside. This product has been shown to be an activator in the synthesis of DNA and RNA.Purezza:Min. 95%Lamivudine 5'-monophosphate ammonium salt
CAS:Lamivudine 5'-monophosphate ammonium salt is a novel antiviral agent that inhibits the viral polymerase by competing with natural dNTPs. It has been shown to be effective against Hepatitis B virus (HBV) and human immunodeficiency virus type 1 (HIV-1). Lamivudine 5'-monophosphate ammonium salt is a synthetic nucleoside that is phosphorylated to form its active form, lamivudine 5'-triphosphate ammonium salt. This drug has been shown to inhibit tumor growth in vivo and in vitro.Formula:C8H15N4O6PSPurezza:Min. 95%Peso molecolare:326.27 g/mol4-Bromo-2-methoxypyrimidine
CAS:4-Bromo-2-methoxypyrimidine is a synthetic compound that is used in the synthesis of other compounds. It reacts with alcohols, boronic acids, and benzyl halides to form heterocycles or pyrimidine compounds. The reaction system is catalytic and chemoselectively. 4-Bromo-2-methoxypyrimidine has been shown to have anticancer activity against various cell lines in vitro. It also possesses an ability to react with aryl boronic acids, such as those found in 2-pyridinones, to form new compounds. This reaction is catalyzed by palladium on carbon or copper chloride in the presence of a base. The new compounds have shown anti-inflammatory and cytotoxic activities against cancer cells.Purezza:Min. 95%5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine
CAS:5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine is a nucleoside, a type of chemical compound containing both a sugar (deoxyribose) and an organic molecule (a base). It is an antiviral agent that inhibits the production of viral DNA by inhibiting the enzyme DNA polymerase. 5-Fluoro-1-(2'-L-menthyloxycarbonyl-1'-3'-oxathiolan-5'-yl)-cytosine is also an anticancer agent that can inhibit the production of cancer cells in vitro and in vivo. This product is a novel monophosphate nucleotide analog with high purity and CAS number 1422361-25-8.Purezza:Min. 95%5-Bromo-2',3'-dideoxyuridine
CAS:5-Bromo-2',3'-dideoxyuridine is a nucleoside analogue that is used as a chemotherapeutic drug against various types of cancer. It has been shown to have anti-tumour activity by interfering with the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). 5-Bromo-2',3'-dideoxyuridine binds to the sugar ring in DNA and inhibits the enzyme DNA polymerase from synthesizing DNA. This drug also stabilizes conformations of the molecule, which are responsible for its pharmacological effects.
5-Bromo-2',3'-dideoxyuridine can be found in two different crystal structures, monoclinic and tetragonal. The monoclinic form is stabilized by hydrogen bonds between the puckers in the sugar ring and hydrogen bonds to neighboring molecules. This form is more soluble than the tetragonal form,Purezza:Min. 95%8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite
8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel nucleoside that is synthesized from 8-bromo-2'-deoxyadenosine and N,N,-diisopropylethylamine. It has been shown to have anticancer, antiviral, and antiinflammatory activities. This compound is also used as an activator in the synthesis of DNA and RNA. The purity of this product exceeds 99% and it has been modified for use with automated synthesizers.Formula:C43H52BrN8O6PPurezza:Min. 95%Peso molecolare:887.82 g/mol5-Aza-3-deaza-N4-DMF-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite
5-Aza-3-deaza-N4-DMF-5'-O-DMT-2'-O-methylcytidine 3'-CE phosphoramidite is a novel modified nucleoside that is synthesized by the reaction of 5-Aza-3,8-(N4,N4)-dimethyl-1,2:5,6:8:10,11:12,-tetradeoxyribonucleosides with 2'-O,O'-Dimethoxytrityl Chloride. This product has been shown to be an activator and to have antiviral and anticancer activities. It also has a high purity and quality.Formula:C43H55N6O8PPurezza:Min. 95%Peso molecolare:814.91 g/mol3'-Deoxy-3'-fluoroinosine
CAS:3'-Deoxy-3'-fluoroinosine is a nucleoside analog that has been shown to have cytotoxic effects. It inhibits the growth of nematodes and other parasites by blocking the deacetylation of lipids in the cell membrane, which leads to their death. 3'-Deoxy-3'-fluoroinosine has also been shown to inhibit trypanosomiasis and leishmania infections by preventing the synthesis of purines and pyrimidines. This drug binds to 6-chloropurine ribonucleotide reductase, thereby inhibiting the production of nucleic acids. 3'-Deoxy-3'-fluoroinosine is not active against mammalian cells, which may be due to its inability to penetrate cell membranes efficiently.Purezza:Min. 95%N6-Formyl adenosine
CAS:N6-Formyl adenosine is an endogenous nucleotide that is dynamically modified in the human body. N6-Formyl adenosine is a reactive modification of adenosine and has been shown to be present in DNA, RNA, and proteins. It is also found in human cells and tissues, where it can be demethylated by enzymes such as DNA methyltransferase. This modification may have implications for research into the nature of messenger RNA (mRNA), which plays a crucial role in protein synthesis. N6-Formyl adenosine has been used to distinguish between mature and immature mRNA molecules by fluorescence analysis.Formula:C11H13N5O5Purezza:Min. 97 Area-%Peso molecolare:295.25 g/mol2-(Piperidin-4-Yloxy)Pyrimidine Dihydrochloride
CAS:2-(Piperidin-4-Yloxy)Pyrimidine Dihydrochloride is a nutrient that can be used for soil fertilization and weed control. It is a non-selective herbicide that inhibits the growth of all plants. This compound breaks down in the environment, so it is environmentally friendly. 2-(Piperidin-4-Yloxy)Pyrimidine Dihydrochloride can be applied to the soil or sprayed on leaves to control weeds. It is more efficient at controlling weeds than potassium chloride, which is another type of fertilizer.Formula:C9H13N3O·2HClPurezza:Min. 95%Peso molecolare:252.14 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol
1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol is a modified nucleoside that is used as an anticancer agent. It is a synthetic analogue of 2'-deoxyadenosine 5'-monophosphate (dAMP) and has been shown to be a DNA activator. It also has antiviral properties against herpes simplex virus type 1 and influenza A virus. This drug is a novel high purity and high quality product that can be used for research purposes.Formula:C25H23N5O4Purezza:Min. 95%Peso molecolare:457.49 g/mol2-Amino-4-(4-chlorophenyl)pyrimidine
CAS:2-Amino-4-(4-chlorophenyl)pyrimidine is a antiviral agent and an inhibitor of ribonucleotide reductase. It is used for the treatment of cytomegalovirus infection, herpes zoster, and chronic myeloid leukemia. 2-Amino-4-(4-chlorophenyl)pyrimidine is also used in anticancer therapy. This drug inhibits DNA synthesis by binding to the deoxyribose moiety of ribonucleosides and diphosphates in the DNA precursor pool. The drug has been shown to be active against human lymphocytic leukemia cells as well as human erythroleukemia cells but not against normal human lymphocytes.
Formula:C10H8ClN3Purezza:Min. 95%Peso molecolare:205.64 g/molO6-Benzyl-N2,3-etheno-2'-deoxy-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine
CAS:O6-Benzyl-N2,3-etheno-2'-deoxy-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine is a modified nucleoside with antiviral and anticancer activities. It can be used in DNA synthesis to produce oligonucleotides that have been modified at the 2' position. O6-Benzyl-N2,3-etheno-2'-deoxy-3',5'-O-[tetrakis(isopropyl)-1,3-disiloxanediyl] guanosine is also active against diphosphate reductase. CAS No. 148437-94-9Formula:C31H45N5O5Si2Purezza:Min. 95%Peso molecolare:623.89 g/mol2'-Deoxy-N4,N4,5-trimethylcytidine
CAS:2'-Deoxy-N4,N4,5-trimethylcytidine is a monophosphate nucleoside that is used as a precursor for the synthesis of DNA. It can be modified to produce phosphoramidites and ribonucleosides. 2'-Deoxy-N4,N4,5-trimethylcytidine has antiviral activity against herpes viruses and cytomegalovirus (CMV). It also has anticancer activity in animal models.
Formula:C12H19N3O4Purezza:Min. 95%Peso molecolare:269.3 g/molFluorescein-beta-d-glucopyranoside
CAS:Fluorescein-beta-D-glucopyranoside is a monophosphate, modified nucleoside that is synthesized from fluorescein by the action of beta-D-glucose. It can be used as an activator or antiviral agent. Fluorescein-beta-D-glucopyranoside has been shown to have anticancer and antitumor properties by inhibiting RNA synthesis in tumor cells. Fluorescein-beta-D-glucopyranoside has also been shown to have antiinflammatory properties.Formula:C26H22O10Purezza:Min. 95%Peso molecolare:494.4 g/molRef: 3D-FF182334
1g6.435,00€2gPrezzo su richiesta5g13.834,00€250mgPrezzo su richiesta500mgPrezzo su richiesta5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite
CAS:5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite is a novel nucleoside phosphoramidite. It is an activator of DNA polymerase for the synthesis of diphosphate analogues of ribonucleosides and deoxyribonucleosides. This compound has been used in the synthesis of antiviral and anticancer agents, as well as in research on the development of new antiviral drugs.Purezza:Min. 95%5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine
5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has antiviral activity. It is an activator of the ribonucleotide reductase enzyme and inhibits the synthesis of DNA, RNA and proteins. 5'-Amino-N-Boc-5'-deoxy-2',3'-O-isopropylideneadenosine has shown anticancer activity in several animal models.Purezza:Min. 95%Adenosine 5’-Diphosphate-13C5
CAS:Adenosine 5’-diphosphate (ADP) is a potent activator of the G-protein coupled receptor, P2Y. This receptor has been shown to be present on platelets, which are cells that are involved in the clotting process. ADP also inhibits the ion channel activity of the Na+, K+ ATPase. The effects of ADP on myocardial infarct have been studied in a model system consisting of isolated papillary muscle from rats. Adenosine 5’-diphosphate is not an inhibitor of protein synthesis, but does inhibit polymerase chain reaction amplification. It is used as a pharmacological agent for bowel disease and for treatment of chronic obstructive pulmonary disease.END>Formula:C5C5H15N5O10P2Purezza:Min. 95%Peso molecolare:432.2 g/mol3',5'-Di-O-benzoyl-2'-O-methyl-5-methyluridine
3',5'-Di-O-benzoyl-2'-O-methyl-5-methyluridine is an activated nucleoside which is a synthetic nucleoside analog. It has been shown to be an effective antiviral and anticancer agent, as well as a potential antiviral drug against HIV. 3',5'-Di-O-benzoyl-2'-O-methyl-5-methyluridine is also a potent inhibitor of RNA synthesis in cells, which may lead to the development of new drugs for the treatment of viral infections.Purezza:Min. 95%2'-Deoxy-4-desmethylwyosine
CAS:2'-Deoxy-4-desmethylwyosine is a nucleoside that has been modified to contain a deoxyribose sugar. The monophosphate form of this compound has been shown to activate the DNA synthesis and promote cellular proliferation by stimulating the enzyme ribonucleotide reductase. 2'-Deoxy-4-desmethylwyosine is also an antiviral agent that blocks the synthesis of viral ribonucleic acid (RNA). This compound has been synthesized from phosphoramidites and purified to high purity and high quality.Formula:C13H15N5O4Purezza:Min. 95%Peso molecolare:305.29 g/mol2'-Deoxy-5-(methylthio)-uridine
CAS:2'-Deoxy-5-(methylthio)-uridine is a synthetic nucleoside that is used for antiviral and anticancer purposes. It is phosphorylated to 2'-deoxy-5-(methylthio)-2'-fluoro-uridine, which inhibits viral RNA synthesis by acting as a chain terminator. 2'-Deoxy-5-(methylthio)-uridine also has anticancer properties due to its ability to inhibit DNA replication and protein synthesis.
Formula:C10H14N2O5SPurezza:Min. 95%Peso molecolare:274.29 g/mol6-Fluorescein dT phosphoramidite
CAS:6-Fluorescein dT phosphoramidite is a novel compound that has been shown to have anticancer, antiviral and antimalarial activities. It is an activator of nucleotides and nucleosides, which are important in DNA synthesis and RNA synthesis. This product is synthesized by the chemical modification of 6-fluorescein with the dT phosphoramidite group. The purity of this product has been determined by high performance liquid chromatography (HPLC) analysis and found to be greater than 98%.Formula:C79H89N6O17PPurezza:Min. 95%Peso molecolare:1,425.56 g/mol2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine
2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine is an antiviral nucleoside with anticancer activity. It is a synthetic analog of cytidine, modified at the 2' position with an azido group and a benzoyl group. 2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine has shown in vitro antiviral activity against herpes simplex virus type 1 (HSV1) and type 2 (HSV2), as well as human immunodeficiency virus type 1 (HIV1). It also has anticancer activity against human erythroblasts, leukemia cells, and lymphoma cells.Formula:C37H34N6O7Purezza:Min. 95%Peso molecolare:674.7 g/mol6-Aminothymine
CAS:6-Aminothymine is a polyamine that exerts its inhibitory activity by hydrogen bonding to the enzyme's active site. It has been shown to inhibit protein synthesis and growth factor synthesis in HL-60 cells. 6-Aminothymine also has cancer inhibiting properties, which may be due to its ability to bind DNA and interfere with replication or transcription.Formula:C5H7N3O2Purezza:Min. 95%Peso molecolare:141.13 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å
N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å is a synthetic nucleoside analog with antiviral activity. This compound inhibits the synthesis of viral DNA by inhibiting the action of DNA polymerase and reverse transcriptase. The N4-benzoyl group in this compound prevents viral DNA synthesis by acting as an inhibitor for thymidylate synthase, which converts thymine to thymine monophosphate. It also has been shown to be active against cytomegalovirus (CMV).Purezza:Min. 95%6-Chloro-9-(5-o-dimethoxytrityl-β-D-2-deoxyribofuranosyl)purine
CAS:6-Chloro-9-(5-o-dimethoxytrityl-β-D-2-deoxyribofuranosyl)purine is a phosphoramidite. It is used as an antiviral agent and has been shown to be effective against HIV, herpes zoster, and other viruses. 6-Chloro-9-(5-o-dimethoxytrityl)-2'-deoxyribofuranosyl)purine is a novel nucleotide derivative that inhibits the replication of RNA and DNA by inhibiting the synthesis of viral nucleic acids. This compound can also be used for the treatment of cancer cells.Formula:C31H29ClN4O5Purezza:Min. 95%Peso molecolare:573 g/mol6-(Trifluoromethyl)uracil
CAS:6-(Trifluoromethyl)uracil is a synthetic analog of uracil, which is a nucleobase that is found in RNA. It can be synthesized by reacting phosphorus oxychloride and trifluoromethyl chloride to form the corresponding chloroformate ester, followed by hydrolysis with anhydrous potassium carbonate. The compound has been shown to inhibit bacterial growth in bioassays and also has the ability to react with amines. 6-Trifluoromethyluracil has a constant chlorine atom that forms hydrogen bonds with other molecules, such as ammonia or amines, which may have antibacterial properties.Formula:C5H3F3N2O2Purezza:Min. 95%Peso molecolare:180.08 g/mol5'-O-tert-Butyldimethylsilyluridine
CAS:5'-O-tert-Butyldimethylsilyluridine (5'-O-TBDMSU) is a nucleoside that is used in the synthesis of nucleic acid probes. It is selective for the uridine residues in RNA and DNA, which are found at the 5' position. Sodium hydride reacts with this compound to form the corresponding hydroxyl group. This allows for further nucleobase additions or halogen substitutions to be made to the molecule, as well as desilylation reactions. 5'-O-TBDMSU can also be used to synthesize heteroaromatic nucleic acids and nucleotide derivatives.Formula:C15H26N2O6SiPurezza:Min. 98 Area-%Colore e forma:PowderPeso molecolare:358.46 g/mol9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine
9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine is a nucleoside analogue that is a potent inhibitor of viral replication. It inhibits the synthesis of DNA and RNA by inhibiting enzymes involved in the metabolism of nucleosides (e.g., phosphoramidites, deoxyribonucleosides, ribonucleosides). 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine has been shown to have antiviral activity against HIV, herpes simplex virus type 1 (HSV1), and herpes simplex virus type 2 (HSV2).Formula:C35H36FN5O7Purezza:Min. 95%Peso molecolare:657.69 g/molN2,3',5'-Tri-O-acetyl-2'-deoxy-O5-diphenylcarbamoyl-a/b-guanosine
N2,3',5'-Tri-O-acetyl-2'-deoxy-O5-diphenylcarbamoyl-a/b-guanosine is a novel nucleoside with anticancer activity. The compound can be activated to the corresponding monophosphate by phosphorylation and is also a potent antiviral agent. In addition, the compound has good chemical stability and high purity. This product is suitable for use in biochemical research and as an additive in pharmaceuticals.
Purezza:Min. 95%3'-O, N4-Diacetyl-2'-deoxycytidine
3'-O, N4-Diacetyl-2'-deoxycytidine is a modified nucleoside that has anticancer and antiviral activities. It inhibits the synthesis of DNA by preventing the formation of deoxyribonucleotide triphosphates. 3'-O, N4-Diacetyl-2'-deoxycytidine is a novel nucleoside with high purity and high quality. The CAS number for this product is 61428-37-5. This product can be used as starting material in the synthesis of phosphoramidites or modified oligonucleotides.
Formula:C13H17N3O6Purezza:Min. 95%Peso molecolare:311.29 g/mol2',3',5'-Tri-O-benzoylguanosine
CAS:2',3',5'-Tri-O-benzoylguanosine is an anticancer nucleoside that inhibits the synthesis of DNA and RNA. It is a novel synthetic monophosphate nucleoside analog with antiviral and antitumor activities. 2',3',5'-Tri-O-benzoylguanosine has shown to be effective against human leukemia cells, lymphoma cells, prostate cancer cells, and melanoma cells in vitro. The drug also inhibits the growth of HIV virus in vitro.
Formula:C31H25N5O8Purezza:Min. 95%Peso molecolare:595.56 g/molN4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer
CAS:N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer is a novel deoxyribonucleoside monomer. It is an antiviral, activator and high purity compound that can be used as a building block for the preparation of modified oligodeoxynucleotides. N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer is synthesized by reacting 7'-O-(benzoyl)ribose with trityl chloride in the presence of morpholine to form the corresponding benzyl ester.Formula:C35H32N4O4Purezza:Min. 95%Colore e forma:White solid.Peso molecolare:572.65 g/molb-Nicotinamide-D adenine dinucleotide reduced form
CAS:Prodotto controllatoNicotinamide-adenine dinucleotide (NADH) is a coenzyme that plays an essential role in cellular metabolism. NADH has been shown to have neuroprotective effects by improving cerebellar perfusion and reducing the severity of granule cell death in the cerebellum of experimental animals. It also inhibits synaptic activity and improves Purkinje cell survival. NADH is found in granules cells, which are located in the cerebellar cortex. These cells release this molecule when activated by an action potential, which leads to increased calcium levels inside neurons and subsequent neurotransmitter release. The major form of NADH found in these cells is NADH-NAD+ oxidoreductase (EC 1.6.5.3). The activity of this enzyme can be inhibited by a number of compounds, including nicotinamide adenine dinucleotide reduced form (NADH-NAD+ reductase), which may have therapeutic value for treating Parkinson'sFormula:C21H29N7O17P3DPurezza:Min. 95%Peso molecolare:746.43 g/molCytidine hemisulfate salt
CAS:Cytidine hemisulfate salt is a postulated inhibitor of the blood group antigen. It inhibits the phosphatase activity of blood group-specific phosphatases, which may be caused by its specific inhibition of α-tocopherol and phenolphthalein. Cytidine hemisulfate salt has been shown to inhibit both adenylic and uridylic phosphatases, but does not inhibit other phosphatases. This drug is also an antigen that can stimulate B cells, which produce antibodies against it. Cytidine hemisulfate salt is found in DNA and RNA.Formula:C9H13N3O5H2SO4Purezza:Min. 95%Peso molecolare:292.26 g/mol2'-Deoxyguanosine phosphoramidite dimer
2'-Deoxyguanosine phosphoramidite dimer is a modified nucleoside that is used in the synthesis of DNA. It has anticancer activity and is used as an activator for other nucleotide analogues. This product has CAS number 743-88-2, purity of 99%, and molecular weight of 204.23 g/mol.Purezza:Min. 95%(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-d
CAS:(2'R)-N-Benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate (2'R)-N-benzoyl-2'-deoxy-2'-fluoro-2'-methylcytidine 3',5'-diphosphate) is a modified nucleoside that is an antiviral, anticancer, and activator of DNA synthesis. It has been shown to be the first synthetic nucleotide analogue to have significant activity against HIV in vitro. The synthesis of this compound starts with the diphosphate or monophosphate form of cytidine. The phosphate group is removed and replaced with a 2'R benzoyl group. This process is followed by fluorination and methylation steps. Finally, the 5' hydroxyl group is cleaved to give 2'R -N benzoyl 2'-deoxy-2'-fluoro-2'-Formula:C31H26FN3O7Purezza:Min. 95%Peso molecolare:571.55 g/mol
