
Nucleosidi
Trovati 3569 prodotti di "Nucleosidi"
5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å
5'-O-DMT-thymidine-3'-succinyl CPG 2000 Å is a synthetic nucleoside that contains an acetyl group at the 5' position. The succinyl group has been added to the 3' position of the nucleoside and is bonded to a carrier molecule (2000 Å). This product is used as an activator in DNA synthesis, it also has antiviral and anticancer activities.Colore e forma:PowderSpacer-c3 cep
CAS:Spacer-C3 Cep is a novel modified nucleoside phosphoramidite. It has been chemically modified with a spacer arm and 3-Cep (1,2-diaminoethane). Spacer-C3 Cep is an activator for DNA polymerases, which are enzymes that synthesize DNA from deoxyribonucleosides. The modified nucleoside phosphoramidite has antiviral and anticancer activities. It can be used in the synthesis of oligodeoxyribonucleotides for gene therapy or as a monophosphate for the preparation of DNA probes. Spacer-C3 Cep can also be used to synthesize ribonucleotide analogs that inhibit viral replication by inhibiting RNA synthesis.
Formula:C33H43N2O5PPurezza:Min. 95%Peso molecolare:578.7 g/molMalonyl coenzyme A lithium salt - 90%
CAS:Malonyl coenzyme A lithium salt - 90% is a fatty acid that is involved in the biosynthesis of fats. It is also involved in the synthesis of prostaglandins, which are hormone-like substances that have a wide variety of effects on many different tissues. Malonyl coenzyme A lithium salt - 90% may be useful for the treatment of insulin resistance and obesity due to its ability to stimulate glucose uptake by fat cells and increase insulin sensitivity. The following product details are for a supplement:Formula:C24H38N7O19P3S·xLiPurezza:Min. 95%Peso molecolare:853.58 g/mol2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine
CAS:2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine (ddC) is a nucleoside with antiviral activity. The mechanism of action is not well understood, but ddC has been shown to inhibit the proliferation of human immunodeficiency virus (HIV). It is also active against isolates of herpes simplex virus and vesicular stomatitis virus. The elimination half-life of ddC in humans is about 8 hours. In humans, this drug is eliminated by methylation and glucuronidation reactions. The pharmacokinetics of ddC have been studied in animals, including rats and rabbits, with preliminary indications that the elimination half-life may be longer than in humans.
Formula:C9H10FN3O3Purezza:Min. 95%Peso molecolare:227.19 g/molCytidine-5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:Cytidine-5'-O-(1-thiotriphosphate) lithium salt is a monophosphate nucleotide analog. It is soluble in water, and is used in the synthesis of DNA and RNA. Cytidine-5'-O-(1-thiotriphosphate) lithium salt has antiviral, anticancer, and anti-inflammatory properties. This compound can be used as an activator for phosphoramidites in the synthesis of DNA or RNA. Cytidine-5'-O-(1-thiotriphosphate) lithium salt is a novel nucleoside that can be used in the synthesis of modified oligonucleotides.Formula:C9H16N3O13P3S·xLiPurezza:Min. 95%Peso molecolare:499.22 g/mol1-(β-D-Arabinofuranosyl)-5-hydroxymethyluracil
CAS:A hetero-base functionalised ara-nucleoside
Formula:C10H14N2O7Purezza:Min. 95%Peso molecolare:274.23 g/mol3'-Phosphoadenosine-5'-phosphosulfate lithium salt hydrate
CAS:Universal sulfonate donor for in vivo sulfonation by sulfotransferasesFormula:C10H15N5O13P2S·xLi·yH2OPurezza:Min. 60 Area-%Colore e forma:White PowderPeso molecolare:507.27 g/mol2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine
CAS:2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine is an analog of the nucleoside uridine. It is a potent inhibitor of protein synthesis in cells, and has the potential to be used as a long-term treatment for tuberculosis. 2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine has been shown to inhibit the production of tumor necrosis factor alpha (TNFα) in mice with influenza or hepatitis, and also inhibits the replication of HIV. This drug may also have antibacterial properties due to its ability to inhibit bacterial DNA gyrase and topoisomerase IV. 2'-O-Methyl-p-thiouridynyl-(3'->5')-2'-deoxyadenosine binds to an antigen on the surface of cells, activating them.Formula:C20H26N7O10PSPurezza:Min. 95%Peso molecolare:587.5 g/mol4'-α-C-Methylcytidine
CAS:4'-a-C-Methylcytidine is a nucleoside that is synthesized from 4'-a-C-methyluridine. It has antiviral and anticancer properties, and has been shown to be a potent activator of the immune system. The modified nucleosides in this compound are thought to be less toxic than other cytotoxic agents. 4'-a-C-Methylcytidine is also used as a building block for the synthesis of DNA, RNA and phosphoramidites.Purezza:Min. 95%Colore e forma:PowderPeso molecolare:257.24 g/mol7-Deaza-2'-C-ethynyladenosine
CAS:7-Deaza-2'-C-ethynyladenosine (7DAA) is a research inhibitor that is classified as a polymerase inhibitor. It binds to the active site of the viral NS5B polymerase and inhibits RNA synthesis, which leads to virus replication. 7DAA has shown activity against hepatitis B virus (HBV) and hepatitis C virus (HCV). It also shows multifunctional properties in its inhibition of HBV genotypes A1, A3, and D1. In addition, 7DAA interacts with the RNA binding site on HCV polymerase protein and prevents binding of the viral RNA genome to this site. 7DAA also inhibits HIV replication by preventing assembly of the reverse transcriptase enzyme complex at an early stage.Formula:C13H14N4O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:290.27 g/mol3'-O-Methylinosine
CAS:3'-O-Methylinosine is a synthetic nucleoside that inhibits the synthesis of viral DNA and RNA by interacting with the enzyme ribonucleotide reductase. This antiviral agent has been shown to be effective against a wide range of viruses, including human cytomegalovirus, herpes simplex virus type 1, varicella-zoster virus, and influenza A virus. 3'-O-Methylinosine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.
Formula:C11H14N4O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:282.25 g/mol3'-Deoxy-5-methyluridine
CAS:3'-Deoxy-5-methyluridine (3'-DMAU) is a synthetic nucleoside that is used in the treatment of viral infections. 3'-DMAU has antiviral and anticancer activity, and it has been used to synthesize DNA for genetic engineering. It has shown promising results in the treatment of HIV as well as in the prevention of cancer metastasis. 3'-DMAU inhibits DNA synthesis by binding to the enzyme RNA polymerase, which blocks its interaction with ribonucleosides, thus inhibiting RNA synthesis. In addition, 3'-DMAU causes cell death by inhibiting protein synthesis. The drug is activated by phosphorylation to form 5'-triphosphate and 5'-diphosphate derivatives, which inhibit DNA and RNA synthesis at multiple sites within the cell.Formula:C10H14N2O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:242.23 g/mol5′-O-DMT-LNA N-Bz 5-Me cytidine
CAS:5′-O-DMT-LNA N-Bz 5-Me cytidine is a protected LNA cytidine nucleoside.Formula:C39H37N3O8Purezza:Min. 95%Peso molecolare:675.73 g/mol9-(β-D-Arabinofuranosyl)adenine 5'-monophosphate
CAS:9-(β-D-Arabinofuranosyl)adenine 5'-monophosphate (Ara-AMP) is a prodrug that is converted to adenine arabinoside in vivo. It is used as an antiviral agent for the prevention of hepatitis B and C. Ara-AMP inhibits viral DNA synthesis by acting as a competitive inhibitor of adenosine triphosphate, which is required for viral DNA polymerase activity. Ara-AMP also has antiviral properties against some RNA viruses, such as HIV and influenza virus. Ara-AMP can be administered orally or by injection, making it suitable for use in children who are unable to take oral medication.Formula:C10H14N5O7PPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:347.22 g/mol2-Chloroadenosine
CAS:2-Chloroinosine is an adenosine receptor agonist; metabolically stable analog of adenosineFormula:C10H12ClN5O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:301.69 g/molALS-8176
CAS:ALS-8176 is a benzimidazole compound that has been shown to be effective against both wild-type and syncytial viruses. It is also active against the hepatitis B virus, which causes fulminant hepatitis in humans and death in 30% of cases. The antiviral activity of ALS-8176 was demonstrated by its ability to inhibit viral DNA synthesis and to prevent the release of new viral particles. ALS-8176 has also been shown to have a broad spectrum of activity against paramyxoviruses, including mumps, measles, and respiratory syncytial virus (RSV). This drug can be used for the treatment of influenza A and B when administered during the early stages of infection. ALS-8176 blocks the antibody response to influenza virus infection as well as monoclonal antibody binding sites on the hemagglutinin protein, preventing fusion between infected cells.Formula:C18H25ClFN3O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:433.86 g/mol3′-Guanylic acid disodium
CAS:3′-Guanylic acid disodium is a nucleoside analog that inhibits viral replication and tumor growth. It is an antiviral agent that is active against herpes simplex virus type 1 and type 2, as well as cytomegalovirus. 3′-Guanylic acid disodium is also an anticancer agent that has shown promising results in animal models of glioma, lymphoma, lung cancer, and breast cancer. The molecule inhibits the synthesis of DNA by competitively inhibiting the action of ribonucleotide reductase. 3′-Guanylic acid disodium also inhibits protein synthesis by blocking the conversion of ribonucleotides to deoxyribonucleotides. This drug has been shown to have a high purity and quality with no detectable impurities or contaminants.
Formula:C10H14N5O8P•Na2Purezza:Min. 95%Peso molecolare:409.2 g/mol3'-Deoxyadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:3'-Deoxyadenosine-5'-triphosphate sodium salt is a nucleotide that has been shown to be effective in chemotherapy. It is a substrate for the synthesis of DNA, RNA, and ATP. 3'-Deoxyadenosine-5'-triphosphate sodium salt is also a building block for DNA polymerase, which is an enzyme that synthesizes DNA from a template. It has been shown to have anticancer activity in drug-resistant cells and can be used as an alternative to purine analogs such as 6-mercaptopurine or cladribine. 3'-Deoxyadenosine-5'-triphosphate sodium salt has been shown to inhibit the production of nucleotides by blocking their conversion into triphosphates, which are necessary for DNA replication and repair. This inhibition leads to apoptosis in cells with high levels of nucleotide turnover such as cardiac and myeloid cells. The drug interactions may depend on theFormula:C10H16N5O12P3Purezza:Min. 95%Colore e forma:Colorless PowderPeso molecolare:491.18 g/mol2'-O-Propargyladenosine
CAS:2'-O-Propargyladenosine is a modified nucleoside that belongs to the group of deoxyribonucleosides. It is an activator of viral DNA polymerases, which causes the synthesis of viral DNA to stop. This compound has antiviral and anticancer activities. 2'-O-Propargyladenosine has been shown to be effective against various human cancer cell lines in vitro and in vivo. It is a synthetic nucleoside with high purity, showing no detectable impurities by HPLC analysis.
Formula:C13H15N5O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:305.29 g/molAdenosine 5'-monophosphate sodium
CAS:Adenosine 5'-monophosphate sodium is a nucleotide that is involved in the energy metabolism of cells. It has been shown to inhibit oxidative injury and to activate signal pathways in response to external stimuli, such as glucose deprivation. Adenosine 5'-monophosphate sodium can be synthesized from ATP by the enzyme adenosine kinase.
Formula:C10H13N5O7P·NaPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:369.2 g/molN6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an analog of adenosine triphosphate (ATP). It is used in the study of protein kinase C. ATP and its analogs are able to phosphorylate proteins and regulate their activity. This study has shown that N6-benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an atp analog that activates protein kinase C, leading to the phosphorylation of proteins. This analog also inhibits tyrosine kinases, which may be due to its ability to inhibit the reuptake of serotonin and other transmitters.Formula:C17H22N5O13P3·xNaPurezza:Min. 95%Colore e forma:Colorless PowderPeso molecolare:597.3 g/molent-abacavir
CAS:Ent-abacavir is a drug that belongs to the group of antiretroviral drugs. It has minimal toxicity and has been shown to be effective in long-term treatment of HIV/AIDS. Ent-abacavir is also used as part of active antiretroviral therapy, which includes at least three or four different drugs. It inhibits the activity of reverse transcriptase, an enzyme involved in the replication process of HIV and other retroviruses. This drug has been shown to have few drug interactions with other medications, although caution should be taken when using ent-abacavir with drugs that are metabolized by cytochrome P450 enzymes. Ent-abacavir is not recommended for use in patients who have chronic viral hepatitis or who have a body mass index greater than 30 kg/m2 because its pharmacokinetic properties may be altered in these individuals.Formula:C14H18N6OPurezza:Min. 95%Peso molecolare:286.33 g/mol3-Acetylpyridine adenine dinucleotide disodium, reduced form
CAS:Reduced synthetic analog of NADH with an acetylpyridine modification. It is used as a reducing substrate to study the mechanisms of NAD(P)+-dependent reductases and to probe the active sites and catalytic processes of these important enzymes through its altered spectroscopic and binding properties. The disodium salt ensures good solubility for biochemical applications.Formula:C22H30N6O14P2•Na2Purezza:Min. 95%Colore e forma:Slightly Yellow PowderPeso molecolare:710.43 g/molRef: 3D-NA30684
10mgPrezzo su richiesta25mg454,00€50mg698,00€100mg1.018,00€250mg1.843,00€500mg2.494,00€N2-Ethyl-2′-deoxyguanosine - 98 % HPLC
CAS:N2-Ethyl-2′-deoxyguanosine is an important metabolite of N2-ethyl-3′,5′-dideoxyadenosine (NEDA) and has been detected in urine samples from Sprague-Dawley rats. The biological properties of this metabolite are not well understood, but it has been shown to have genotoxic effects in mammalian cells and to be carcinogenic in a rat model. N2-Ethyl-2′-deoxyguanosine is also able to enhance the repair of damaged DNA and has functional groups that are similar to those found in cancer cells.
Formula:C12H17N5O4Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:295.29 g/molZeatin riboside
CAS:Zeatin riboside is a naturally occurring compound that belongs to the group of nucleotides. It is synthesized in plants and bacteria, and has been shown to have physiological activities in both these organisms. Rootstocks are typically used as the optimum concentration for zeatin riboside. Zeatin riboside has been shown to be effective against bacterial strains that cause plant diseases, such as bacterial strain Xanthomonas campestris pv. corylina. Zeatin riboside also inhibits the growth of plant pathogens by increasing adenine nucleotide levels in root cells, which leads to an increase in photosynthetic activity and a decrease in the production of chemical pesticides. The optimum pH for zeatin riboside is 8-9.Formula:C15H21N5O5Purezza:Min. 90%Colore e forma:PowderPeso molecolare:351.36 g/mol8-Nitroguanosine
CAS:8-Nitroguanosine is a nucleotide analogue that inhibits the activity of cyclic GMP in cells. It has been found to inhibit the growth of bacteria and cancer cells, as well as to stimulate the production of reactive oxygen species in brain cells. 8-Nitroguanosine has also been shown to inhibit the activity of cyclase enzymes in liver cells, which may be useful for treating liver disease. 8-Nitroguanosine is used as a chemical base for monoclonal antibodies that are used to study brain functions and pathogenic mechanisms.Formula:C10H12N6O7Purezza:Min. 95%Peso molecolare:328.24 g/molLamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution
Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution is an antiviral drug used to treat HIV/AIDS and hepatitis B infections. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, acting by blocking the viral enzyme reverse transcriptase. Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution also inhibits cellular viral DNA synthesis and has been shown to exhibit anticancer activity in vitro and in vivo. This product is synthesized from raw materials through a novel process that involves modification of the phosphoramidite monophosphate with tetratriethylammonium salts.Formula:C32H74N7O12P3SPurezza:Min. 95%Peso molecolare:873.96 g/mol2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite
2'-Deoxy-3'-O-DMT-N2-isobutyrylguanosine 5'-CE phosphoramidite is a 5'-3’ “reverse” (or “inverse”) amidite.Formula:C44H54N7O8PPurezza:Min. 95%Peso molecolare:839.94 g/molMorpholino A monomer
CAS:Morpholino A is a modified nucleoside amidite used to prepare morpholino oligomersFormula:C38H37ClN7O4PPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:722.17 g/molAdenosine 2',3'-cyclic monophosphate
CAS:Adenosine 2',3'-cyclic monophosphate triethylammonium salt (AMP-TEA) is a structural analogue of adenosine. It is a potent inhibitor of protein synthesis by preventing the phosphodiesterase activity of cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase. AMP-TEA can be used as a tool to study translation in tissue culture, as well as to examine the effects on protein synthesis and other biochemical reactions that are regulated by cyclic nucleotides. It is also used for the preparation of tissue samples for enzymatic analysis or for radiolabeling experiments. AMP-TEA has an optimum pH of 4.5, but can be used at lower or higher pH values. The optimal temperature range for use is between 0°C and 50°C, with the maximum stability occurring at 37°C.Formula:C10H12N5O6PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:329.21 g/molAdenosine 5′-O-(1-thiotriphosphate) sodium, mixture of R and S isomers
Please enquire for more information about Adenosine 5′-O-(1-thiotriphosphate) sodium, mixture of R and S isomers including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C10H16N5O12P3S•Na3Purezza:Min. 95%Peso molecolare:592.25 g/mol2'-O-(2-Methoxyethyl)adenosine 5'-α-thiotriphosphate sodium
2'-O-(2-Methoxyethyl)adenosine 5'-a-thiotriphosphate sodium salt is a synthetic nucleoside with antiviral and anticancer properties. It is an analog of adenosine 5'-triphosphate (ATP) in which the ribose sugar has been replaced by a 2'-O-(methoxyethyl) moiety. It has shown to be cytotoxic against cancer cells, and it is a potent activator of human telomerase, the enzyme that synthesizes telomeres at the end of chromosomes. This compound has been shown to have high purity and quality and does not have any CAS numbers assigned to it.Formula:C13H18N5Na4O13P3SPurezza:Min. 95%Peso molecolare:669.25 g/mol2',3'-O-Isopropylideneinosine
CAS:2',3'-O-Isopropylideneinosineis a nucleoside for use in research applications
Formula:C13H16N4O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:308.3 g/molN2-Acetyl-5'-O-DMT-guanosine
CAS:N2-Acetyl-5'-O-DMT-guanosine is a novel anticancer nucleoside that has been synthesized to mimic the natural nucleotides found in DNA. It is phosphorylated to N2-acetyl-5'-O-DMT-guanosine monophosphate, which can be converted back to the active form of N2-acetyl-5'-O-DMT guanosine by phosphatases. This agent activates DNA synthesis and inhibits viral replication, including HIV and herpes simplex virus. The antiviral activity is due to its inhibition of viral DNA polymerase and diphosphate kinase.
Purezza:Min. 95%2'-Deoxy-3,4,5,6-tetrahydrouridine
CAS:2'-Deoxy-3,4,5,6-tetrahydrouridine (2DTHR) is a cytidine deaminase inhibitor that is used in vitro to inhibit the production of tumor necrosis factor (TNF). 2DTHR has been shown to be active against hepatocellular carcinoma cells. It is also reactive with tumor tissue and can be eliminated at a rate similar to that of deoxycytidine kinase. This drug binds to the enzyme target and inhibits its activity by increasing enzyme levels, which causes cell death. 2DTHR inhibits TNF production in tumor tissue by binding to cytidine deaminase and preventing conversion of cytidine into uracil. This drug has been shown to cause tumor inhibition in vitro.
Formula:C9H16N2O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:232.23 g/mol1-b-D-Arabinofuranosyluracil 5'-monophosphate
CAS:1-b-D-Arabinofuranosyluracil 5'-monophosphate is a pyrimidine nucleotide analog. Because of its structural similarity to natural nucleotides, it can interact with enzymes involved in nucleic acid synthesis. It is also a metabolite of Ara-U (arabinosyluracil), which is itself a compound studied for its biological activity. Scientists could potentially use this molecule in research to study how cells process and use nucleotides, and to understand how changes in nucleotide structure can affect biological processes.Formula:C9H13N2O9PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:324.18 g/mol5-Methoxyuridine-5'-triphosphate sodium, 100mM aqueous solution
CAS:5-Methoxyuridine-5'-triphosphate is a monophosphate nucleoside that serves as a precursor for the synthesis of 5-methoxyuridine (5MU) and other nucleosides. It has antiviral effects, and is used in the treatment of herpes zoster infection. 5-Methoxyuridine-5'-triphosphate is an analog of uridine and deoxyribonucleosides with antiviral activity, which can be used to treat herpes zoster infection. This drug also has anticancer properties, which may be due to its ability to inhibit DNA synthesis by inhibiting ribonucleotide reductase and DNA polymerase, leading to cell death.Formula:C10H17N2O16P3•NaxPurezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:514.17 g/molKinetin riboside-5'-monophosphate sodium salt
CAS:Kinetin riboside-5'-monophosphate sodium salt is a synthetic nucleotide that has been modified to include a phosphate group at the 5' position. Kinetin riboside-5'-monophosphate sodium salt is an activator of DNA synthesis and can be used for the treatment of viral infections. It also shows anticancer activity and is effective against cancer cells that are resistant to other cancer drugs.Formula:C15H16N5Na2O8P·H2OPurezza:Min. 95%Colore e forma:PowderPeso molecolare:489.29 g/mol[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate
CAS:[(2S,6R)-6-{Thymin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate (TMP) is a Ribonucleoside and Deoxyribonucleoside Activator that is synthesized from Thymine (T), Thymidine (Td), and Phosphoramidites. TMP is a novel synthetic derivative of thymine with the ability to activate DNA synthesis reactions. TMP has been shown to provide high quality nucleotides with high purity in a single step reaction.Formula:C31H34ClN4O5PPurezza:Min. 95%Colore e forma:White To Light (Or Pale) Red SolidPeso molecolare:609.05 g/mol5'-o-DMT-N4-benzoyl-5-methyl-2'-o-methylcytidine 3'-ce phosphoramidite
CAS:5'-O-DMT-N4-benzoyl-5-methyl-2'-O-methylcytidine 3'-ce phosphoramidite is a high purity, diphosphate, CAS No. 166593-57-3, Modified, Anticancer, DNA. It is a novel activator monophosphate that can be used for the synthesis of phosphoramidites for oligonucleotide synthesis and as a novel building block for nucleosides and deoxyribonucleosides. 5'-O-DMT-N4-benzoyl-5-methyl-2'-O-methylcytidine 3'-ce phosphoramidite has been shown to have anticancer activity in vitro. The cytotoxic effect of this compound is mediated by its ability to inhibit DNA replication and induce apoptosis in human leukemia cells.
Formula:C48H56N5O9PPurezza:Min. 95%Peso molecolare:878.00 g/mol2'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a nucleoside with anticancer properties. It is a phosphoramidite, which is an analog of the natural nucleotide guanosine, where the 2'-hydroxyl group has been replaced by a methylene group. This compound is used in DNA synthesis and RNA synthesis. It can be used as a monophosphate or diphosphate. It also has antiviral and anti-inflammatory activities, as well as N2-methylamino moiety that can be used for the treatment of cancer and inflammatory diseases such as arthritis.
Formula:C11H15N5O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:281.27 g/mol7-deaza-dG-CE Phosphoramidite
CAS:7-deaza-dG-CE Phosphoramidite is a monophosphate nucleotide, which is synthesized by modification of the 7-deaza-dG ribonucleoside. It has an antiviral and anticancer activity, and is used as a building block for novel drugs. 7-Deaza-dG-CE phosphoramidite has been shown to inhibit tumor growth and induce apoptosis in Hep2 cells. It also inhibits HIV replication in vitro. The compound is chemically stable and does not react with other biomolecules.Formula:C44H54N7O7PPurezza:Min. 95%Peso molecolare:823.9 g/mol5'-O-Tosylthymidine
CAS:5'-O-Tosylthymidine is a bifunctional reagent that is used in the synthesis of DNA. It is a nucleophilic, inorganic compound that reacts with the electrophilic acrylonitrile group on 5'-hydroxythymidine to form a stable thiophosphate linkage. The reaction takes place stepwise and is catalyzed by an enzyme called DNA polymerase. This product has been used as an antimetabolite in medicine, mainly for treating leukemia.
Formula:C17H20N2O7SPurezza:Min. 95%Peso molecolare:396.42 g/mol5’-O-DMT-2’-O,4’-C-methylene-5-methyluridine
CAS:5’-O-DMT-2’-O,4’-C-methylene-5-methyluridine is a nucleoside that is used as an antiviral and anticancer agent. It is a novel compound that has not been previously described in the literature. 5’-O-DMT-2’-O,4’-C methylene 5 methyluridine has been shown to inhibit the replication of the herpes virus in vitro (in cell culture) and in vivo (in animals). This compound also inhibits the proliferation of cancer cells by inhibiting DNA synthesis. It may be used as an anticancer agent or an antiviral agent.
Purezza:Min. 95%Thymidine-3',5'-diphosphate disodium salt
CAS:Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.Formula:C10H14N2Na2O11P2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:446.15 g/molGuanosine-5'-[(a,beta)-methyleno]triphosphate sodium salt
CAS:Guanosine-5'-[(a,b)-methyleno]triphosphate sodium salt (GpCpp) is a non hydrolyzable nucleosidePurezza:Min. 95%N6-Benzyladenosine 5'-diphosphate sodium salt - 10 mM aqueous solution
CAS:N6-Benzyladenosine 5'-diphosphate sodium salt is a modified nucleoside that has a high purity, which is suitable for synthesis of DNA or RNA. It can be used in the modification of deoxyribonucleosides, ribonucleosides, and phosphoramidites. N6-Benzyladenosine 5'-diphosphate sodium salt has been shown to have anticancer effects and antiviral effects. This drug also has novel properties such as an ability to inhibit the proliferation of cancer cells.Formula:C17H21N5O10P2Purezza:Min. 95%Colore e forma:Colorless PowderPeso molecolare:517.32 g/molGuanosine 5'-diphosphate sodium
CAS:Pyruvate kinase substrate
Formula:C10H15N5O11P2•Na2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:466.19 g/molXanthosine-5'-triphosphate triethylammonium salt - 100 mM aqueous solution
CAS:Inhibitor of adenylyl and guanylyl cyclaseFormula:C10H15N4O15P3·xC6H15NPurezza:Min. 95%Colore e forma:Colorless PowderPeso molecolare:524.17 g/molUridine-3',5'-cyclic monophosphate sodium salt
CAS:Uridine-3',5'-cyclic monophosphate sodium salt is a phosphotriester that is an intermediate in the biosynthesis of nucleosides. It is also a phosphodiesterase inhibitor, which means it inhibits the breakdown of cyclic nucleotides and allows them to accumulate. This drug has been shown to increase platelet production and has anti-inflammatory effects. Uridine-3',5'-cyclic monophosphate sodium salt is a human metabolite that can be synthesized from uridine, which is present in DNA, RNA, and food sources such as meat, eggs, and milk. The synthesis of uridine-3',5'-cyclic monophosphate sodium salt requires phosphoramidite as a precursor.
Formula:C9H10N2O8P·NaPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:328.2 g/mol
