Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3569 prodotti di "Nucleosidi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
S-(4-Nitrobenzyl)-6-thioinosine
CAS:S-(4-Nitrobenzyl)-6-thioinosine (SBT) is a nucleoside with biochemical properties that are similar to those of adenosine. SBT is an equilibrative nucleoside, which means that it can bind to both DNA and RNA. It has been shown to be effective in inhibiting the growth of cancer cells in vitro by binding to DNA. SBT binds to the purine nucleotide transporter and prevents the uptake of uridine, adenosine, and other nucleosides into the cell. This process leads to a decrease in intracellular concentrations of these nucleosides. SBT also binds to divalent metal ions such as copper or zinc, which may affect its activity on cancer cells.Formula:C17H17N5O6SPurezza:Min. 98 Area-%Colore e forma:White Off-White PowderPeso molecolare:419.41 g/molN4-Acetylcytidine
CAS:N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.Formula:C11H15N3O6Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:285.25 g/mol1-(2'C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one
CAS:1-(2'C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one (1) is a synthetic nucleoside that has been modified to be activated with the addition of a phosphoryl group. It inhibits viral replication by inhibiting viral DNA synthesis. It also inhibits cancer cell growth, and has shown potential as an antiviral agent against HIV, herpes simplex type 2, and influenza A viruses. 1 is a novel monophosphate nucleoside with high purity and high quality. CAS No. 2072145-17-4.Purezza:Min. 95%N4-Benzoyl-2'-O-methylcytidine
CAS:N4-Benzoyl-2'-O-methylcytidine is a triester of cytidine that is used in various biochemical research applications. It is enzymatically synthesized from cytidine and benzoyl chloride. N4-Benzoyl-2'-O-methylcytidine has been shown to have the same electrophoretic mobility as 5-hydroxyl cytidine, but it does not react with hydroxylamine to produce the corresponding hydroxylated product. This compound has also been used to study nucleic acid structure and function.
Formula:C17H19N3O6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:361.35 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine
CAS:N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine (BTS) is a novel phosphoramidate monophosphate nucleoside analog that has been modified to be resistant to the ribonuclease A enzyme. BTS is an activator of DNA synthesis and inactivator of RNA synthesis, which makes it useful for the treatment of cancer and antiviral infections. This drug is synthesized using high quality reagents and can be used for the production of phosphoramidites to produce high purity oligonucleotides.Formula:C23H31N5O5SiPurezza:Min. 95%Colore e forma:PowderPeso molecolare:485.61 g/mol3’-Deoxy-3’-fluoro-6-azauridine
CAS:Please enquire for more information about 3’-Deoxy-3’-fluoro-6-azauridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurezza:Min. 95%1-(b-L-Arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt
1-(b-L-Arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is a novel antiviral agent that is synthesized from ribonucleosides. It is an activator of the monophosphate form of RNA polymerase and inhibits the synthesis of DNA in cells. This drug has also been shown to be effective against cancer cells and may be useful for treatment of leukemia.Purezza:Min. 95%b-L-2',3'-Dideoxy-5-fluorocytidine
CAS:b-L-2',3'-Dideoxy-5-fluorocytidine is a pyrimidine nucleoside that inhibits the deoxycytidine kinase enzyme, which catalyzes conversion of deoxycytidine to cytidine. It has potent inhibition against human lymphocytes and liver cells, as well as virus replication. b-L-2',3'-Dideoxy-5-fluorocytidine has potent antitumor activity in vitro and in vivo, with an inhibitory effect on immunodeficiency and hepatitis. This drug also has a potent inhibitory effect on T-cell growth in cell culture. b-L-2',3'-Dideoxy-5-fluorocytidine is converted to 5'-deoxyfloxuridine by cellular enzymes and then to 5'-deoxyuridylate by the enzyme uridylate kinase. The latter compound inhibits DNA synthesis by inhibiting thymidylFormula:C9H12FN3O3Purezza:Min. 95%Peso molecolare:229.21 g/mol2'-O-Methyl-N6-phenoxyacetyladenosine
CAS:2'-O-Methyl-N6-phenoxyacetyladenosine is a phosphoramidite nucleoside that is used in the synthesis of DNA and RNA. It has antiviral, anticancer, and antiribonucleases properties. The chemical structure of 2'-O-Methyl-N6-phenoxyacetyladenosine is similar to that of adenosine, but contains a methyl group on C2' position and an oxyalkyl group on N6. This compound can be used as a novel anticancer agent and has been shown to have high affinity for the purine receptor, inhibiting cancer cell proliferation by activating the p53 tumor suppressor pathway.Formula:C19H21N5O6Purezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:415.41 g/molC2,C8-Dimethyladenosine
C2,C8-Dimethyladenosine is a nucleoside that is used for antiviral and anticancer purposes. It is synthesized from 2′-deoxyadenosine monophosphate, which is in turn synthesized from adenosine triphosphate and diphosphate. C2,C8-Dimethyladenosine has been shown to inhibit viral replication and induce cell death of cancer cells. It binds to viral RNA polymerase, thereby inhibiting the formation of new viral particles. This compound also inhibits DNA synthesis by binding to the active site of DNA polymerase α and interfering with the process of base pairing. C2,C8-Dimethyladenosine has also been shown to have an antimetastatic effect by inducing apoptosis in tumor cells.Purezza:Min. 95%9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine
CAS:9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a modified monophosphate nucleoside that is an antiviral agent. It can be used as a building block for the synthesis of ribonucleosides, deoxyribonucleosides, and phosphoramidites. This product has been shown to have anticancer properties and may be used in the development of new anticancer drugs. 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine has also been shown to inhibit the growth of bacteria by inhibiting DNA synthesis.Purezza:Min. 95%2,6-Diamino-9-(2'-deoxy-2'-fluoro-β-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(2'-deoxy-2'-fluoro-β-D-ribofuranosyl)purine is a modified purine nucleoside analog. This compound has modification that have the potential to influence its ability to interfere with nucleic acid synthesis, such as DNA or RNA.Formula:C10H13FN6O3Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:284.25 g/mol8-Azidoadenosine 5'-monophosphate sodium salt
CAS:8-Azidoadenosine 5'-monophosphate sodium salt is an azido-conjugated adenosine monophosphate derivative used to introduce a label on oligonucleotides. A click reaction between the azide-functionalised nucleotide and a terminal alkyne-functionalised labelled moiety (with either a fluorophore or biotin) generates a stable conjugate containing a triazole link.Formula:C10H13N8O7PPurezza:Min. 95%Peso molecolare:388.23 g/mol5-Aminoimidazole-4-carboxylic acid-1-b-D-ribofuranose 5'-monophosphate
CAS:5-Aminoimidazole-4-carboxylic acid-1-b-D-ribofuranose 5'-monophosphate (AIRC) is a synthetase that catalyzes the reaction between ribulose 5-phosphate and ammonia to form 1,3,5-triaminoimidazole ribotide. AIRC is found in plants such as solanum tuberosum, where it functions in the synthesis of starch. It has been shown to be involved in physiological processes, including enzymatic reactions and growth factors. The enzyme is activated by hydrochloric acid and pyridine phosphate, which are its substrates. The enzyme is also inhibited by dry weight and synthetic pathway inhibitors. This enzyme has been used as a model for studying the effects of linear models on metabolic pathways.Formula:C9H14N3O9PPurezza:Min. 95%Peso molecolare:339.2 g/mol3'-O-Allylguanosine
3'-O-Allylguanosine is a antiviral agent that belongs to the group of synthetic nucleosides. It is a monophosphate analog of guanosine and an activator of ribonucleotide reductase. 3'-O-Allylguanosine has been shown to be effective against cancer cells in vitro. It has also been shown to inhibit DNA synthesis and promote DNA degradation in human leukemia cells, suggesting its potential use for the treatment of leukemia.
Formula:C13H17N5O5Purezza:Min. 95%Peso molecolare:323.3 g/molAdenosine 5'-diphosphate magnesium salt
CAS:Adenosine 5'-diphosphate magnesium salt (ADP-Mg) is a pharmacological agent that has inhibitory properties. It is used as a model system to study platelet function and the effect of adenosine on platelet aggregation. ADP-Mg is also used as a reagent in the study of protein synthesis and regulation. This chemical has been shown to potentiate the activity of serotonin receptors, which may contribute to its anti-inflammatory effects. Adenosine 5'-diphosphate magnesium salt also inhibits papillary muscle contractions by inhibiting Ca2+ currents, leading to an improved ejection fraction in patients with congestive heart failure.Formula:C10H13N5O10P2·MgPurezza:Min. 95%Colore e forma:PowderPeso molecolare:449.49 g/mol7-Deaza-2'-deoxy-7-iodoguanosine
CAS:7-Deaza-2'-deoxy-7-iodoguanosine is a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm. 7-Deaza-2'-deoxy-7-iodoguanosine can be synthesized using the following general equation:
Formula:C11H13IN4O4Purezza:Min. 97 Area-%Colore e forma:White PowderPeso molecolare:392.16 g/molN4-Benzoyl-2-aza-3’-deazaadenine
CAS:N4-Benzoyl-2-aza-3’-deazaadenine is a modified nucleoside that is synthesized from the natural deoxyribonucleoside adenine. It has been shown to have antiviral and anticancer properties. N4-Benzoyl-2-aza-3’-deazaadenine is a DNA Activator and can be used in the treatment of viral infections, such as HIV and herpes, as well as cancer. The drug binds to the viral DNA polymerase and prevents it from making new copies of the virus. This results in an accumulation of defective viruses within infected cells and ultimately cell death.Purezza:Min. 95%2-Thiocytidine
CAS:2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.
Formula:C9H13N3O4SPurezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:259.28 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.Purezza:Min. 95%
