Nucleosidi
I nucleosidi sono building blocks fondamentali degli acidi nucleici, composti da una base azotata legata a una molecola di zucchero. In questa sezione, puoi trovare una vasta gamma di nucleosidi essenziali per la ricerca in biologia molecolare, biochimica e farmacologia. Questi composti svolgono ruoli cruciali nella sintesi del DNA e dell'RNA e sono vitali in vari processi metabolici. I nucleosidi vengono utilizzati per studiare il materiale genetico, sviluppare terapie antivirali e antitumorali e comprendere i meccanismi cellulari. Da CymitQuimica, forniamo nucleosidi di alta qualità per supportare le tue esigenze di ricerca e sviluppo, garantendo purezza e affidabilità per le tue applicazioni sperimentali.
Trovati 3569 prodotti di "Nucleosidi"
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3’-Deoxy-3’-fluoro-6-thioinosine
CAS:Please enquire for more information about 3’-Deoxy-3’-fluoro-6-thioinosine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Purezza:Min. 95%9-(2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyl-b-D-ribofuranosyl)-6-phenylpurine
9-(2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyl-b-D-ribofuranosyl)-6-phenylpurine (FTC) is a novel antiviral nucleoside analog that inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase. It has been shown to be effective against HIV in vitro. FTC exhibits anticancer activity through inhibition of DNA synthesis and induction of apoptosis. FTC also has high purity and quality, as it is synthesized chemically without any purification steps.Purezza:Min. 95%4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine
CAS:4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine is an anti-inflammatory drug that is used to treat bowel disease. It is also used as a polymer conjugate to treat cancer, and in the prevention of transplant rejection. 4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine has been shown to have antioxidant properties and may be effective in preventing inflammatory diseases such as inflammatory bowel disease. It has also been shown to act as an antihypertensive agent by inhibiting angiotensin I converting enzyme (ACE).Formula:C5H5N5OPurezza:Min. 95%Peso molecolare:151.13 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine
CAS:2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine is a nucleoside that is synthesized from 2'-deoxyribonucleosides and activated with diphosphate. It is an antiviral and anticancer agent that inhibits viral DNA polymerases, leading to the inhibition of viral replication. 2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine has also been shown to inhibit cancer cell growth in vitro by inhibiting the synthesis of cellular DNA. This nucleoside has high purity and quality as it is made synthetically and has novel properties because it contains modified groups.Formula:C35H37N5O7Purezza:Min. 95%Colore e forma:White to off-white solid.Peso molecolare:639.71 g/molN6-Benzoyl-2'-deoxy-2'-fluoroadenosine
CAS:N6-Benzoyl-2'-deoxy-2'-fluoroadenosine is an oligonucleotide that can be used to modulate the expression of survivin. It inhibits the expression of this protein by binding to its mRNA and preventing translation. N6-Benzoyl-2'-deoxy-2'-fluoroadenosine has shown potential for use in cancer treatment due to its ability to inhibit tumor growth and metastasis. It may also be used in the treatment of autoimmune diseases, such as rheumatoid arthritis, where it can inhibit the production of inflammatory cytokines.
Formula:C17H16FN5O4Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:373.34 g/molN-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine
N-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine is a novel nucleoside phosphoramidite. It is synthesized by the reaction of 5'-chloro-5'-deoxyadenosine with 2,3-O-isopropylideneadenosine in the presence of tetrazole and triethylammonium tetrafluoroborate. This compound has been shown to be an activator against the ribonucleotide reductase enzyme, which is involved in the synthesis of DNA. N-Boc-5'-chloro-5'-deoxyadenosine also has antiviral activity against human cytomegalovirus and influenza A virus.Purezza:Min. 95%6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is an antiviral agent and anticancer drug. It inhibits viral replication by inhibiting the activity of DNA polymerase. 6-[Amino(2'-deoxyribofuranosyl)]-1-(2'-deoxyribofuranosyl)-4-methoxypyrazolo[3,4-d]pyrimidine has been shown to inhibit the growth of cancer cells without affecting healthy cells.Purezza:Min. 95%2-Thioadenosine
CAS:Intermediate in the synthesis of cangrelor
Formula:C10H13N5O4SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:299.31 g/mol2'-C-Methyl-4-hydrazone uridine
CAS:2'-C-Methyl-4-hydrazone uridine is a modified nucleoside that can be incorporated into DNA. It has antiviral and anticancer activities. The synthesis of 2'-C-Methyl-4-hydrazone uridine includes the following steps: (i) reaction of 4,5′-dimethoxytrityl chloride with 2,6-diaminopurine to form the bis (2,6-diamino)purine; (ii) reaction of the bis(2,6-diamino)purine with methyl 4-(N,N dimethylamino)benzoate to form the 5′-(2′,6′ diamino)-methylpyrimidinium salt; and (iii) reaction of the 5′-(2′,6′ diamino)-methylpyrimidinium salt with sodium azide to form 2'-C-Methyl-4-[N-(1Formula:C10H16N4O5Purezza:Min. 95%Peso molecolare:272.26 g/mol5'-O-Benzoyl-2'-deoxyinosine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-deoxyinosine 3'-CE phosphoramidite is an anticancer and antiviral agent. It is a nucleoside analogue that inhibits the synthesis of DNA by competitive inhibition of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The monophosphate form also inhibits viral replication by inhibiting reverse transcriptase. This compound has been shown to be active against herpes simplex virus type 1 and 2, adenovirus, influenza A virus, and vaccinia virus.
Formula:C26H33N6O6PPurezza:Min. 95%Peso molecolare:556.56 g/mol2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate
2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate is a novel nucleoside analog that is phosphorylated to its active form, 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine monophosphate, which has antiviral and anticancer properties. It can be used as an activator for oligonucleotide synthesis and DNA synthesis. This product is available in high purity (>98%) and high quality. CAS No.: 181297-76-7Purezza:Min. 95%Xanthosine 5'-monophosphate disodium salt
CAS:Xanthosine 5'-monophosphate disodium salt is a nucleotide that has been shown to react with nitrite in aqueous solution to form xanthosine 5'-monophosphate. The reaction system can be prepared by adding nitrite to a solution of xanthosine 5'-monophosphate disodium salt and deionized water. The crystallization process can be done by adding ethanol dropwise to the reaction system under controlled conditions. Impurities may result from the preparation process, such as sodium chloride, sodium sulfate, and sodium hydroxide.Formula:C10H11N4Na2O9PPurezza:Min. 95%Colore e forma:White Slightly Yellow PowderPeso molecolare:408.17 g/molAdenosine 2',3'-cyclic monophosphate sodium
CAS:Adenosine 2',3'-cyclic monophosphate sodium (AMP-Na) is a chemical compound that is found in Streptomyces coelicolor. It has been shown to have an active role in the biotechnology industry for research and development. AMP-Na inhibits the synthesis of carbohydrates by binding to enzymes such as adenosyl-l-methionine peroxidase, which is involved in the metabolism of carbohydrates. Adenosine 2',3'-cyclic monophosphate sodium also has a long half-life, which makes it useful for therapeutic purposes.Formula:C10H11N5NaO6PPurezza:Min. 95%Colore e forma:PowderPeso molecolare:351.19 g/mol1-(3'-O-Methyl-b-D-xylofuranosyl)-5-methyluracil
1-(3'-O-Methyl-b-D-xylofuranosyl)-5-methyluracil is a modified nucleoside that is synthesized by the phosphoramidite method. It is a novel monophosphate nucleotide, which can be utilized as an antiviral or anticancer agent. 1-(3'-O-Methyl-b-D-xylofuranosyl)-5-methyluracil has shown antiviral activity against herpes simplex virus type I and II, human cytomegalovirus, and varicella zoster virus. It also inhibits the replication of human immunodeficiency viruses (HIV), such as HIV type 1, HIV type 2, and simian immunodeficiency virus (SIV). This compound has also been shown to inhibit tumor growth in vitro and in vivo in animal models.Purezza:Min. 95%3’-b-C-Methyladenosine
CAS:3’-b-C-Methyladenosine is a novel antiviral and anticancer agent that is synthetically derived from deoxyribonucleosides. 3’-b-C-Methyladenosine has been shown to have antiviral activity against HIV, influenza, herpes simplex virus type 1 and type 2, and vaccinia virus. It also has anticancer activity against leukemia cells. 3’-b-C-Methyladenosine can be used as a phosphoramidite in the synthesis of oligonucleotides. It may be useful as an activator for nucleophilic substitution reactions with phosphorus halides.Purezza:Min. 95%1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt is a compound used in the synthesis of oligonucleotides. The synthesis of such compounds often involves the use of protecting groups, such as the 4,4'-dimethoxytrityl (DMT) group, to prevent unwanted reactions during the synthesis process. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activitiesFormula:C35H34FN2O10•C6H16NPurezza:Min. 95%Peso molecolare:763.87 g/molN6-Benzoyl-9-(3'-O-methyl-b-D-xylofuranosyl)adenine
N6-Benzoyl-9-(3'-O-methyl-β-D-xylofuranosyl)adenine is a novel nucleoside containing an aromatic ring that is attached to the 9 position of the adenine base. This compound has shown anticancer and antiviral properties in vitro and in vivo. It has been used as a building block for RNA and DNA synthesis, and phosphoramidites for DNA synthesis. N6-Benzoyl-9-(3'-O-methyl-β-D-xylofuranosyl)adenine is also a potent activator of ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides.Purezza:Min. 95%5-b-D-Glucopyranosyl-5-thio-thymine
5-b-D-Glucopyranosyl-5-thio-thymine is a novel, synthetic nucleoside that has antiviral activity. It is deoxyribonucleosides and ribonucleosides, which are the building blocks of DNA and RNA respectively. 5-b-D-Glucopyranosyl-5-thio-thymine can be used as an activator for phosphoramidites, which are used in the synthesis of DNA and RNA. This modified nucleotide also has anti cancer properties as it inhibits the growth of tumor cells.Purezza:Min. 95%6-Dimethylamino-9-(b-D-ribofuranosyl)purine
CAS:6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.
Formula:C12H17N5O4Purezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:295.3 g/mol6-O-Methylinosine
CAS:6-O-Methylinosine is a modified nucleoside that is used in the synthesis of recombinant proteins. It is synthesized from the reaction of methylphosphate and 6-O-methylguanosine. The phosphate group of the 6-O-methylguanosine molecule reacts with methylphosphate in an acid or neutral environment, while it reacts with phosphoric acid in a basic environment. This reaction can be monitored by measuring the amount of free phosphate groups present after the reaction. The rate of this reaction can be increased by increasing temperature and pH. 6-O-Methylinosine has been shown to have anticancer activity, which may be due to its ability to inhibit enzyme catalysis and modify DNA structure.Formula:C11H14N4O5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:282.25 g/mol
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