Antracicline
Le antracicline sono una classe di potenti antibiotici antitumorali ampiamente utilizzati nella chemioterapia del cancro. Questi composti agiscono intercalandosi nel DNA, interrompendo così la funzione della topoisomerasi II e impedendo la replicazione delle cellule cancerose. Le antracicline sono particolarmente efficaci contro una vasta gamma di tumori, tra cui leucemie, linfomi e cancro al seno. Tuttavia, il loro uso è spesso limitato dalla loro cardiotossicità, rendendo la ricerca di formulazioni più sicure ed efficaci un'area chiave di interesse. Presso CymitQuimica, offriamo una selezione di antracicline per supportare la vostra ricerca in oncologia, sviluppo di farmaci e terapia del cancro.
Trovati 173 prodotti di "Antracicline"
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7,8,9,10-Dehydro Doxorubicinone (~70%)
CAS:Prodotto controllatoFormula:C21H14O8Purezza:~70%Colore e forma:NeatPeso molecolare:394.33Doxorubicin Imp B HBr salt
CAS:<p>Doxorubicin Imp B HBr salt is a drug product that is custom synthesized for research and development. It's high purity, analytical, and natural are well suited for pharmacopoeia, drug development, and niche. Doxorubicin Imp B HBr salt has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The CAS No. 148218-14-8 is an impurity standard that can be used in HPLC analysis to determine the purity of Doxorubicin Imp B HBr salt.</p>Formula:C29H34BrNO11BrHPurezza:Min. 95%Peso molecolare:733.4 g/molDoxorubicin Impurity 15
CAS:<p>Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.</p>Formula:C31H38BrNO11Purezza:Min. 95%Peso molecolare:680.54 g/molDes[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone
CAS:<p>Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone is a research and development impurity standard for synthesis. It is a synthetic, high purity compound with a CAS number of 89991-52-6. The chemical is not found in nature and does not have any natural metabolites. Des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone has been shown to be metabolized by the liver into various metabolites that have been identified through analysis of urine samples. The metabolite of des[2-[(2-hydroxyethyl)amino]ethyl] mitoxantrone may be used as an analytical standard for HPLC methods.</p>Formula:C18H19N3O5Purezza:Min. 95%Peso molecolare:357.36 g/molEpirubicin
CAS:Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.Formula:C27H29NO11Colore e forma:SolidPeso molecolare:543.52Mitoxantrone (2-hydroxyethyl)piperazine impurity
CAS:Mitoxantrone is an anticancer drug that is used to treat various types of cancer. Mitoxantrone is a prodrug, which means it needs to be metabolized by the body to become active. The main metabolic pathway for mitoxantrone involves hydrolysis of the 2-hydroxyethyl piperazine impurity and formation of N-desmethylmitoxantrone, which is a metabolite that has been found to be more potent than the parent compound in inhibiting DNA synthesis. This impurity standard is used as a reference substance for quality control purposes during drug development. Mitoxantrone can also be synthesized with high purity and custom synthesis services are available upon request.Formula:C22H26N4O6Purezza:Min. 95%Colore e forma:Brown PowderPeso molecolare:442.47 g/molDoxorubicin Dimer Impurity-1
Doxorubicin Dimer Impurity-1 is a drug product that is used as an HPLC standard. It is a metabolite of doxorubicin and has been shown to inhibit DNA synthesis in vitro. This impurity has been detected in the drug product using HPLC, and the purity of this impurity is greater than 98%. Doxorubicin Dimer Impurity-1 is a synthetic compound that has not been found in natural sources. It has been shown to be metabolized by human enzymes, such as esterases, glucuronidases, glutathione reductase, cytochrome P450 enzymes, and glucuronic acid conjugates. Doxorubicin Dimer Impurity-1 may also have anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis.Formula:C54H56N2O21Purezza:Min. 95%Peso molecolare:1,069.02 g/mol
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