Prodotti naturali e sostanze fitochimiche per origine botanica

<p>Applications Notoginsenoside R1 acts as an anti-inflammatory agent, inhibiting TNF-α induced PAI-1 production in aortic smooth muscle cells in humans.<br>References Zhang, H. et al.: Vasc. Pharmacol., 44, 224 (2006);<br></p>

<p>Applications Typhaneoside is a flavonoid glycoside plant extract with potential ability to treat primary dysmenorrhea through the Shaofu Zhuyu decoction.<br>References Shulan S. et al.: Am. J. Chin. Med., 38, 777 (2010); Huang, X. et al.: J. Chrom. B. Anal. Tech. Biomed. Life Sci., 962, 75 (2014);<br></p>

<p>Stability Hygroscopic<br>Applications Ginsenoside F2 is a bioactive metabolite of the ginsenoside component of Panax ginseng with the ability to regulate element-binding protein cleavage activating protein and transforming growth factor-β pathways. This control over apoptosis can lead to a control over hair growth and hair loss in mammals.<br>References Shin, H. et al.: Biol. Pharm. Bull., 37, 755 (2014); Shin, H. et al.: Eur. J. Pharm., 730, 82 (2014);<br></p>

<p>Applications β-D-Glucopyranosiduronic Acid Propyl Methyl Ester, 2,3,4-Triacetate is an intermediate in the synthesis of Propyl β-D-Glucuronide (P835275), a glucuronide of a short-chained aliphatic alcohol formed via glucuronidation in human liver microsomes in vitro.<br>References Moench, B., et al.: Carbohydrate. Res., 352, 186 (2012);<br></p>

<p>Amorphadiene is a sesquiterpene hydrocarbon, which is a naturally occurring organic compound produced through the mevalonate pathway in plants, particularly in Artemisia annua. It is derived from the enzymatic cyclization of farnesyl diphosphate, mediated by amorphadiene synthase. This compound plays a pivotal role as a precursor molecule in the biosynthesis of artemisinin, an effective antimalarial agent.</p>

<p>Corylifol A is a prenylated flavonoid, which is a bioactive compound derived from the seeds of Psoralea corylifolia. This plant, known for its medicinal properties, is commonly used in traditional Chinese and Indian medicine. The mode of action of Corylifol A primarily involves the modulation of various molecular pathways, including those related to anti-inflammatory and antioxidant activities. It is known to influence enzyme activity and gene expression related to these pathways.</p>

<p>Chlorophyll B is a photosynthetic pigment, which is a vital component in the photosystem of plants, algae, and some bacteria. It serves as an accessory pigment, specifically aiding in the absorption of light. Chlorophyll B is primarily derived from the thylakoid membranes within the chloroplasts of photosynthetic organisms.</p>

<p>Used in herbal products for gout, arthritis and inflammation; mutagen</p>

<p>Forsythoside I is a specialized phenylethanoid glycoside, which is a secondary metabolite found in certain plants like Forsythia suspensa and other related species. These compounds are primarily isolated from the roots and leaves of these plants, known for their rich bioactive compound content. Forsythoside I exhibits a complex mode of action, encompassing antioxidant and anti-inflammatory properties. It achieves this by scavenging free radicals and inhibiting pro-inflammatory cytokine production, thereby modulating oxidative stress and inflammatory pathways at a cellular level.</p>

<p>Evomonoside is a synthetic compound, which is chemically engineered to mimic certain naturally occurring bioactive molecules. It acts through a specific inhibitory mechanism targeting key enzymatic pathways within cellular processes, particularly those involved in metabolic regulation and signal transduction. The compound achieves its effects by binding to the active site of the target enzyme, thereby disrupting the normal function and leading to altered metabolic outputs.</p>

<p>Corynoxine is an autophagy-enhancing compound, which is derived from the traditional Chinese medicinal plant Uncaria rhynchophylla. As an oxindole alkaloid, it acts by modulating intracellular signaling pathways to promote autophagy, the cellular degradation and recycling process essential for maintaining cellular homeostasis. Corynoxine's mode of action involves the upregulation of autophagic flux, potentially through the inhibition of mTOR signaling, which is a central regulator of cell growth and metabolism.</p>

<p>Obtusifolin is a natural compound, which is a bioactive anthraquinone derivative extracted from the seeds of Cassia obtusifolia, a plant known for its medicinal properties. With its unique molecular structure, Obtusifolin exhibits significant anti-inflammatory and antioxidant activities. These properties are primarily due to its ability to modulate various biochemical pathways, including the inhibition of pro-inflammatory cytokines and the scavenging of reactive oxygen species.</p>

<p>1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione is commonly known as Curcumin, a polyphenolic compound derived from the rhizome of the plant Curcuma longa, commonly known as turmeric. It is a natural product with a diverse range of biological activities. Curcumin is known for its antioxidant properties, which enable it to scavenge free radicals and reduce oxidative stress. Furthermore, it exhibits anti-inflammatory effects by inhibiting various molecules involved in the inflammatory pathway, such as NF-κB and COX-2 enzymes.</p>

<p>Tinnevellin glucoside is a natural glycoside, which is derived from the leaves of certain plant species, particularly those belonging to the Tinnevelly senna. This compound is well-characterized by its anti-inflammatory and antioxidant properties. It acts primarily through modulating key inflammatory pathways, thus reducing the production of pro-inflammatory cytokines and reactive oxygen species, which are involved in the inflammatory process.</p>

<p>Rapanone is a bioactive compound classified as a quinone, which is isolated from the Annona species, particularly from the plant family Annonaceae. This compound is known for its interaction with cellular respiration mechanisms, where it specifically acts as an inhibitor of mitochondrial NADH-ubiquinone oxidoreductase, also known as complex I of the electron transport chain. The inhibition of complex I interferes with ATP production by disrupting the proton gradient required for ATP synthesis, leading to a depletion of energy within the cell.</p>

<p>Orcinol glucoside is a biochemical compound that is a glycoside, specifically a glucoside of orcinol. It is typically derived from natural sources such as lichens. The mode of action of orcinol glucoside involves enzymatic hydrolysis, where it can release orcinol under specific conditions, which is useful for various assays.</p>

<p>2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzofuran-1,3(2H,9bH)-dione monosodium is a synthetic compound, classified as a dibenzofuran derivative. This type of product is often sourced through controlled organic synthesis in laboratory settings, adhering to specific reactions that form the complex dibenzofuran structure. With a detailed mechanism of action involving potential interaction with specific biological pathways, this compound may exhibit bioactivity indicative of therapeutic properties, although detailed mechanistic studies are essential to fully elucidate its mode of action.</p>

<p>Forsythoside H is a phenylethanoid glycoside, which is a secondary metabolite derived from natural plant sources, predominantly found in plants of the Forsythia genus. This compound exerts its effects primarily through its strong anti-inflammatory and antioxidant activities. Its mode of action involves the inhibition of pro-inflammatory cytokines and scavenging of free radicals, thereby reducing oxidative stress and inflammation at a cellular level.</p>

<p>C-Veratroylglycol is a phenolic compound, which is a type of product derived from plant sources. It is specifically isolated from various plant species, where it contributes to the structural and defense mechanisms of the plant due to its phenolic nature. The mode of action involves its ability to engage in oxidation-reduction reactions and to bind with proteins and enzymes, affecting various biochemical pathways.</p>

<p>Mexoticin is a natural compound, which is an isolated flavonoid from plants known for its diverse biological activities. It exerts its effects primarily through modulation of key signaling pathways involved in inflammation and oxidative stress. Mexoticin's mode of action involves inhibiting pro-inflammatory cytokines and free radicals, contributing to its potential therapeutic properties.</p>

<p>Please enquire for more information about Exostemin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Erucic acid is a monounsaturated omega-9 fatty acid predominantly found in the seeds of specific plants, such as rapeseed and mustard. It is sourced from the oil extracted from these seeds, which are processed to yield this chemical compound. The mode of action of erucic acid is primarily related to its physicochemical properties, including its long carbon chain and unsaturation, which impact lipid metabolism and biological interactions.</p>

<p>Stictic acid is a secondary metabolite, which is derived from certain species of lichens, particularly those belonging to the genus *Sticta*. This compound is primarily isolated through extraction and purification processes from the lichen thalli. The mode of action of stictic acid involves its potential bioactivity as an antioxidant and antimicrobial agent, which is attributed to its unique structural properties. The acid may interact with various biochemical pathways, influencing cellular defense mechanisms and microbial susceptibility.</p>

<p>Specneuzhenide is a secoiridoid glycoside, which is a bioactive compound derived primarily from the fruits of Ligustrum lucidum, commonly known as glossy privet. This compound is characterized by its unique structure, which includes a glycoside linkage that contributes to its biological efficacy.</p>

<p>5,5-Dimethylhydantoin is a chemical compound, often employed as an intermediate in the synthesis of various derivatives used for stabilization and antimicrobial purposes. It is primarily sourced from organic synthesis processes involving hydantoin derivatives. The mode of action of 5,5-Dimethylhydantoin involves its ability to act as a precursor in the formation of various halogenated compounds that effectively release active ingredients for antimicrobial and disinfection applications.</p>

<p>Dracorhodin is a bioactive natural compound, which is a type of anthocyanin derived from the resin of the Dragon's Blood tree, specifically from the genus Dracaena. This compound exhibits its effects through its antimicrobial and antioxidant properties. Dracorhodin functions by disrupting microbial cell integrity and scavenging free radicals, contributing to its protective and therapeutic potential.</p>

<p>Schumanniofioside A is a naturally occurring saponin, which is derived from the plant *Schumannia kamassi*. This saponin is characterized by its unique glycosidic structure, contributing to its bioactivity. Saponins, including Schumanniofioside A, are known for their ability to modulate various biological pathways. The mode of action of Schumanniofioside A involves disrupting cellular membranes and interacting with cholesterol, which can lead to modulation of immune responses and potential cytotoxic effects on certain cancer cells.</p>

<p>6’’-Malonate-complanatuside is a glycosylated flavonoid, which is a type of phytochemical often found in plants. This compound is derived from natural sources, particularly certain medicinal plants known for their therapeutic properties. Its mode of action primarily involves modulating various biochemical pathways, including antioxidant and anti-inflammatory mechanisms, through its interaction with cellular targets and signaling cascades. By affecting these pathways, it demonstrates potential efficacy in scientific applications.</p>

<p>Geraldone is a synthetic glucocorticoid receptor agonist, which is an engineered compound derived from synthetic chemical processes. It interacts with the glucocorticoid receptor, a type of nuclear receptor that regulates the expression of specific genes involved in modulating the immune response, as well as metabolic and developmental processes.</p>

<p>1-(2,4-Dihydroxyphenyl)-2-(4-hydroxyphenyl)ethanone is a naturally occurring phenolic compound, which is a type of phytoestrogen derived from plant sources, particularly noted for its presence in certain medicinal herbs. This compound exhibits estrogen-like activity, as it can bind to estrogen receptors and modulate estrogenic effects in the body. Its mode of action involves mimicking natural estrogens, making it a subject of interest for hormonal balance studies and therapeutic applications in cases where hormone replacement might be considered.</p>

<p>Iristectorigenin B is a naturally occurring isoflavone, which is a type of phytochemical compound found mainly in plants. This compound is isolated primarily from Iris species. Isoflavones like Iristectorigenin B are known for their role in plant development and defense mechanisms.</p>

<p>Palmitic acid is a saturated fatty acid, which is primarily sourced from natural oils and animal fats. It is a common component of palm oil and also found in butter, cheese, and meat. As a carboxylic acid, it consists of a 16-carbon chain and acts as a basic building block in higher lipids and glycerides.</p>

<p>Cinerin I is a botanical insecticide, which is derived from the pyrethrum plant, specifically harvested from Chrysanthemum cinerariifolium. Its mode of action involves targeting the sodium channels in the nervous systems of insects, leading to paralysis and eventual death. The plant-derived origin of Cinerin I offers an environmentally favorable alternative to synthetic insecticides due to its rapid degradation in the environment, minimizing long-term ecological impact.</p>

<p>Linderane is a bioactive compound, specifically a sesquiterpene lactone, which is extracted from the roots of plants belonging to the Lindera genus. The source of Linderane is primarily the roots of these plants, which are rich in diverse secondary metabolites. The mode of action of Linderane involves modulation of various cellular pathways, making it a potential agent in chemopreventive and therapeutic applications. Its mechanism is thought to interfere with cancer cell proliferation and induce apoptosis through the disruption of normal cellular processes and signaling pathways.</p>

<p>The natural product, Furcatin, is a disaccharide derivative and substrate of furcatin hydrolase. Furcatin hydrolase breaks down furcatin, producing p-allylphenol and the disaccharide acuminose.</p>

<p>L-Palmitoyl carnitine is a lipid-based compound, which is derived from the esterification of palmitic acid with carnitine. It is a naturally occurring derivative that plays a role in cellular lipid metabolism and energy production. The mode of action involves its integration into the mitochondrial membrane, where it facilitates the transport of long-chain fatty acids into mitochondria. This is pivotal for beta-oxidation, the process through which fatty acids are broken down for energy production.</p>

<p>Lavendustin A is a potent tyrosine kinase inhibitor, which is derived from marine sponge sources. It functions by specifically targeting and inhibiting the activity of tyrosine kinases, enzymes crucial for the phosphorylation of tyrosine residues on protein substrates, thereby interfering with signaling pathways essential for various cellular processes.</p>

<p>Viniferol D is a potent antioxidant compound, which is derived from the seeds of Vitis vinifera, commonly known as grapes. This compound contains high levels of polyphenols, particularly proanthocyanidins, which are bioactive molecules with significant free radical scavenging abilities. The mode of action of Viniferol D involves its interaction with reactive oxygen species (ROS), effectively neutralizing these damaging molecules and thereby reducing oxidative stress within cellular environments.</p>

<p>Corylin is a natural compound, classified as a bioactive prenylated flavonoid, which is isolated from the seeds of the plant Psoralea corylifolia, commonly known in traditional medicine for its diverse therapeutic properties. This compound exhibits a multifaceted mode of action, primarily through the modulation of various cellular signaling pathways, including the inhibition of inflammatory mediators and the regulation of cell cycle processes. Its ability to interfere with these biological pathways underpins its potential therapeutic applications.</p>

<p>Gamabufotalin is a cardiotonic bufadienolide, which is a type of steroid compound. It is derived from the secretions of toads belonging to the Bufo genus, particularly the parotoid gland secretions. The mode of action of Gamabufotalin involves inhibition of the Na+/K+-ATPase pump, leading to an increase in intracellular calcium levels, which facilitates increased cardiac contractility. Additionally, this compound has been found to induce apoptosis in cancer cells through pathways such as the regulation of Bcl-2 family proteins and the activation of caspases.</p>

<p>Jasmolin I is a botanical insecticide derived from the pyrethrum plant, Chrysanthemum cinerariifolium. It acts primarily through neurotoxic mechanisms, targeting the sodium channels in the nervous systems of insects. The interaction prolongs the open state of the sodium channels, resulting in repetitive discharges and ultimately paralysis of the target pests.</p>

<p>Bakkenolide is a sesquiterpene lactone, which is a type of bioactive compound commonly found in certain plant species. It is primarily sourced from traditional Chinese medicinal herbs, such as Petasites genus and Centipeda minima. These plants have been used for centuries in herbal medicine due to their therapeutic properties.</p>

<p>Evernic acid is a naturally occurring chemical compound, classified as a depside, which is sourced from various lichen species such as Evernia and Usnea. This compound is formed through the secondary metabolic processes of these symbiotic organisms, which consist of an intricate association between fungi and algae or cyanobacteria. Evernic acid is prominent for its antimicrobial properties and functions by disrupting microbial cell membranes and interfering with metabolic processes.</p>

<p>Fungal metabolite; inhibits actin polymerisation</p>

<p>Zerumbone is a naturally occurring sesquiterpene, which is primarily extracted from the rhizomes of Zingiber zerumbet, a species of wild ginger. As a phytochemical, it has garnered attention for its intriguing mode of action at the molecular level, involving the modulation of cellular signaling pathways. Zerumbone is known to interact with multiple targets, potentially through its reactive α,β-unsaturated carbonyl group, allowing it to form covalent bonds with nucleophilic sites on proteins. This interaction is crucial for its role in altering regulatory proteins involved in inflammation, apoptosis, and anti-neoplastic activities.</p>

<p>(S)-3-[4-(4-Morpholin-4-yl-methyl-benzyloxy)-1-oxo-1,3-dihydro-isoindol-2-yl]-piperidine-2,6-dione is a synthetic small molecule, employed primarily in pharmaceutical research. This compound is derived through a series of sophisticated organic synthesis processes, making it a valuable tool for medicinal chemists and pharmacologists looking to explore novel therapeutic pathways.</p>

<p>6-Methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol is an antimalarial agent, derived from synthetic processes aimed at enhancing the activity of quinoline-based compounds. This compound acts by interacting with the heme moieties in the parasitic digestive vacuole, disrupting the detoxification of heme products, which is essential for parasite survival. By interfering with this process, the compound effectively causes toxic heme accumulation, leading to the death of the Plasmodium species responsible for malaria.</p>

<p>Phyllanthostatin A is a potent bioactive compound, which is a naturally occurring lignan derived from the Phyllanthus acuminatus plant. This species belongs to the Phyllanthaceae family and is known for its diverse array of secondary metabolites. The mode of action of Phyllanthostatin A involves the inhibition of cellular processes that are crucial for the proliferation and survival of cancer cells. It acts by interfering with specific biochemical pathways, which can lead to programmed cell death or apoptosis in malignancies.</p>

<p>Xanthyletin is a naturally occurring coumarin, which is derived from plants, particularly those belonging to the Rutaceae family. It exhibits a range of biochemical interactions as its mode of action, including modulation of enzymatic activities and interference with cellular signaling pathways. Xanthyletin is notably studied for its antiproliferative, antimicrobial, and anti-inflammatory properties.</p>