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Sistema complementare

Sistema complementare

Il sistema del complemento è una parte cruciale della risposta immunitaria, costituito da una serie di piccole proteine che migliorano la capacità degli anticorpi e delle cellule fagocitiche di eliminare i patogeni da un organismo. Queste proteine lavorano insieme per opsonizzare i patogeni, indurre risposte infiammatorie e lisare direttamente le membrane dei patogeni, giocando un ruolo vitale nell'immunità innata e nella funzione immunitaria globale. Da CymitQuimica, offriamo proteine del sistema del complemento di alta qualità per supportare i vostri studi immunologici e la ricerca clinica.

Trovati 156 prodotti di "Sistema complementare"

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  • C3a Receptor Agonist

    CAS:
    <p>C3a Receptor Agonist activates C3aRs, inhibits neutrophil mobilization in ischemia, and promotes neural progenitor differentiation.</p>
    Formula:C27H35N3O2
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:433.59
  • NDT 9513727

    CAS:
    <p>NDT 9513727 is a potent, selective and competitive C5aR1 inverse agonist for the study of inflammatory and immune disorders.</p>
    Formula:C36H35N3O4
    Purezza:99.21%
    Colore e forma:Solid
    Peso molecolare:573.68
  • Complement C5-IN-1

    CAS:
    <p>Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).</p>
    Formula:C24H32N2O6
    Purezza:98.27%
    Colore e forma:Solid
    Peso molecolare:444.52
  • Factor D inhibitor 6

    CAS:
    <p>Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.</p>
    Formula:C23H22ClFN6O3
    Colore e forma:Solid
    Peso molecolare:484.92
  • W-54011

    CAS:
    <p>W-54011: potent non-peptide C5a receptor blocker; binds 125I-C5a (Ki=2.2nM); stops Ca2+ movement, chemotaxis, ROS in neutrophils (IC50=1.6-3.1nM).</p>
    Formula:C30H37ClN2O2
    Purezza:96.8%
    Colore e forma:Solid
    Peso molecolare:493.08
  • Factor B-IN-2

    CAS:
    <p>Factor B-IN-2 is a potent inhibitor (IC50: 1.5 μM) of complement factor B. Factor B-IN-2 can be used to study inflammatory and immune-related diseases.</p>
    Formula:C25H32N2O4
    Colore e forma:Solid
    Peso molecolare:424.53
  • EG01377

    CAS:
    <p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>
    Formula:C26H30N6O6S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:586.68
  • C5aR-IN-1

    CAS:
    <p>C5aR-IN-1, a potent C5aR inhibitor, may aid in researching autoimmune and inflammatory diseases.</p>
    Formula:C36H39F4N3O2
    Colore e forma:Solid
    Peso molecolare:621.71
  • Iptacopan

    CAS:
    <p>Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.</p>
    Formula:C25H30N2O4
    Purezza:99.07% - >99.99%
    Colore e forma:Solid
    Peso molecolare:422.52
  • C5aR-IN-3

    CAS:
    <p>C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.</p>
    Formula:C36H40FN5O3
    Colore e forma:Solid
    Peso molecolare:609.73
  • (Rel)-Factor B-IN-5

    CAS:
    <p>(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.</p>
    Formula:C27H32N2O4
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:448.55
  • Factor B-IN-3

    CAS:
    <p>Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.</p>
    Formula:C24H29N3O4
    Colore e forma:Solid
    Peso molecolare:423.5
  • Pelecopan

    CAS:
    <p>Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).</p>
    Formula:C23H19FN2O4
    Colore e forma:Solid
    Peso molecolare:406.41
  • Factor B-IN-4

    CAS:
    <p>Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.</p>
    Formula:C27H32N2O4
    Colore e forma:Solid
    Peso molecolare:448.55
  • TLQP-21 TFA


    <p>TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.</p>
    Purezza:98%
    Colore e forma:Liquid

    Ref: TM-T38077

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  • TLQP-21 TFA


    <p>TLQP-21 TFA (TLQP-21 Trifluoroacetate) 是一种 VGF 衍生肽,可通过结合后折叠机制激活C3aR1 受体。</p>
    Purezza:98%

    Ref: TM-T35387

    5mg
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