Altri

<p>Cloprostenol sodium salt (ICI 80996 sodium salt) is a synthetic prostaglandin analogue, an agonist at the PGF2α receptor, with luteolytic properties.</p>

<p>Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.</p>

<p>Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β</p>

<p>Malachite green (Solid Green Crystals O) is an N-methylated diaminotriphenylmethane dye used for coloring.</p>

<p>Almotriptan Malate (PNU180638), a selective 5-HT1B/1D receptor agonist, is used in the therapy of Migraine attacks in adults.</p>

<p>Zafirlukast (ICI 204219) is an orally leukotriene D4 receptor (LTD4) antagonist. Zafirlukast has anti-asthmatic and anti-inflammatory effects. Cost-effective and quality-assured.</p>

<p>Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.</p>

<p>Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.</p>

<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>

<p>Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.</p>

<p>Thiazole Orange is a dye that can be used for reticulocyte analysis.</p>

<p>Trientine-2HCl treats Wilson's disease by chelating copper; also stabilizes epoxy resins and aids in isoelectric focusing.</p>

<p>Almotriptan (LAS 31416), a triptan and 5-HT1B/1D agonist, treats migraines by constricting cranial vessels and altering blood flow.</p>

<p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>

<p>Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP).</p>

<p>Palbociclib is an oral CDK4/6 inhibitor, halts Rb phosphorylation, arrests cell cycle, and curbs tumor growth.</p>

<p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>

<p>Zeaxanthin is a dietary carotenoid that accumulates in the retina (particularly the macula) and has antioxidant activity.Cost-effective and quality-assured.</p>

<p>FLTX1, a Tamoxifen derivative, fluoresces to mark estrogen receptors and acts as a strong antiestrogen in breast cancer without affecting the uterus.</p>

<p>Applications A β-adrenergic agonist, related to Clenbuterol and Mabuterol. A repartitioning agent.<br>References Engelhardt, G., et al.: Arzneim.-Forsch., 34, 1625 (1984),<br></p>

<p>Stability Unstable in Methanol<br>Applications Used in the synthesis of cyanogen glycoside. A component contains in antiperspirants, deodorants, body soaps, shampoos, hair rinses, and hair; it inhibits volatile steroid formation by resident bacteria.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marouf, A., et al.: Pharm. Biol., 39, 263 (2001), Fukuda, T., et al.: Biol. Pharm. Bull., 26, 271 (2003), Butler, M., et al.: J. Nat. Prod., 67, 2141 (2004), He, J., et al.: J. Nat. Prod., 69, 121 (2006),<br></p>

<p>Applications An impurity of Nintedanib, which is an antifibrotic drug.<br>References Holdsworth, G.; et al.: Scientific Reports, 7, 1 (2017)<br></p>

<p>Applications The primary labelled metabolite of Diazepam. A ligand for the GABAA receptor benzodiazepine modulatory site. Anxiolytic.Controlled substance (depressant).<br>References Klotz, U., et al.: Br. J. Clin. Pharmacol., 7, 119 (1979), Konishi, M., et al.: J. Pharm. Sci., 67, 1777 (1978), Andreoli, V., et al.: Arzneim.-Forsch., 27, 436 (1977), Miller, R.P., et al.: Toxicol. Appl. Pharmacol., 25, 453 (1973), Margolis, J., et al.: Drug Metab. Dispos., 31, 606 (2003),<br></p>

<p>Impurity Atenolol Desmethyl Impurity<br>Applications Cis-Desmethyl Atenolol is an impurity of Atenolol (A790075), a cardioselective β-adrenergic blocker and antihypertensive agent. Atenolol Desmethyl Impurity<br>References Caplar, V., et al.: Anal. Profiles Drug Subs., 13, 1 (1984);<br></p>

<p>Applications Hexamethyldisilazane is used in the preparation of 5-azacytidine, an antineoplastic drug. Also used in the preparation of β3-AR agonists used in anti-stress formulations.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vujjini, S. et al.: Org. Proc. Res. Dev., 17, 303 (2013); Xu, F. et al.: Org. Lett., 15, 1342 (2013);<br></p>

<p>Applications Hexamethylcyclotrisiloxane is used in the preparation of Silicone coated Celgard-2400 for the adhesion of canine platelets and leucocytes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chawla, A.S.: Biomaterials, 2, 83 (1981)<br></p>

<p>Applications Fulvestrant (F862500) impurity F.<br></p>