Carboidrati e Glicoconiugati

<p>This high purity, custom synthesis, sugar and Click modification, fluorination, Glycosylation, Synthetic, Methylation, Modification is a CAS No. 4-O-b-(2,3,4,6-Tetra-O-acetyl-D-galactopyranosyl)-1,6-anhydro-D-mannopyranoside. This is an Oligosaccharide and Monosaccharide that is a Carbohydrate. This complex carbohydrate has been synthesized from the following monosaccharides: D-mannose (CAS No. 5914) and D-galactose (CAS No. 5632). The molecular weight of this carbohydrate is 591. The chemical formula of this carbohydrate is C36H60O24.</p>

<p>GM1 pentasaccharide, APD-HSA has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the inner galactose residue. Human serum albumin (HSA) is attached β to position 1 of the reducing glucose moiety via an acetylphenylenediamine (APD) linker (Ledeen, 2009). This type of conjugate has been useful in the study of the role of GM1 ganglioside in the diarrheal response caused by cholera toxin (Cervin, 2018).</p>

<p>Cellotrionic acid is a biochemical that is found in the cell walls of bacteria. It is also known as Cellotriose, which is a type of sugar molecule. Cellotriose is composed of three molecules of glucose and it has reactive hydroxy groups. Hydroxy groups are reactive because they can form hydrogen bonds with other molecules. Cellotrionic acid has been shown to have a redox potential, which means that it can either accept or donate electrons. The crystalline structure of cellotrionic acid is similar to that of glucose and can be represented by the formula C6H8O6. Cellotrionic acid has been shown to have aerobic properties, meaning it requires oxygen for metabolism. One example of an aerobic process where cellotrionic acid participates in is the transfer of electrons during the oxidation-reduction reactions in photosynthesis. This biochemical also participates in glycolysis, which occurs during cellular respiration when sugars are broken down into smaller fragments</p>

<p>Man-2b N-glycan is an acidic glycoprotein that is synthesized in the endoplasmic reticulum of mammalian cells. It is a precursor to the oligosaccharide terminal sugar, which connects the glycan to protein. Man-2b N-glycan plays an important role in metabolic disorders such as renal proximal tubule dysfunction and metabolic acidosis by regulating protein synthesis. The Man-2b N-glycan mutation has been shown to lead to changes in cell surface proteins and metabolism, which can be modeled using a glycosylation mutant strain of yeast.</p>

<p>Blood group antigen derivative with spacer arm</p>

<p>Lacto-N-difucohexaose I-BSA is a high purity, custom synthesis sugar that is fluorinated, glycosylated, and methylated. It has been modified to be an oligosaccharide or monosaccharide with saccharides. Lacto-N-difucohexaose I-BSA is a complex carbohydrate that is made up of several different sugars. This product can be used for many purposes such as Click modification and Fluorination.</p>

<p>The linker N-Allyloxycarbonyl-b-lactosamine (NALB) is a bifunctional molecule that can be used to form triplexes with DNA. The NALB has been shown to inhibit the growth of gram-negative bacteria such as Escherichia coli and Haemophilus influenzae by binding to the bacterial cell wall and disrupting its permeability. The linker is synthesized by solid phase synthesis. This process involves the stepwise addition of building blocks in a sequence that is predetermined. The residues are usually protected with protecting groups, which are then removed at the end of the synthesis process.</p>

<p>Lipid A monophosphoryl (MPL) is an adjuvant that stimulates the immune response to vaccines so that optimal protection can be achieved. MPL immunostimulant, a monophosphoryllipid A preparation derived from the lipopolysaccharide (LPS) of Salmonella minnesota R595. MPL is being considered as an adjuvant for a number of human vaccines, and experience to date has shown that it is safe, well tolerated, and able to provide a heightened immune response to coadministered antigens.</p>

<p>GM1a pentasaccharide (ammonium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the inner galactose residue (Ledeen, 2009). GM1a pentasaccharide is the carbohydrate moiety in GM1a ganglioside which interacts and modulates tyrosine kinases, such as, neural tropomyosin receptor kinase A (TrkA), by inducing the release of neurotrophins from fibroblast cells and the epidermal growth factor receptor (EGFR) (Higuero, 2009). Oligosaccharide domain of monosialylated glycosphingolipid GM1 of a-series that specifically interacts with cholera toxin B subunit (CBT) from V. cholerae, heat-labile toxin B subunit (LTB) from E. coli and alpha toxin from C. perfrigens. This ganglioside is abundant in nervous system as well as in other peripheral tissues (Chiricozzi, 2020).</p>

<p>Sialyl-dimeric Lex-nona-APD-HSA is a monosaccharide that belongs to the group of complex carbohydrates. It is a custom synthesis product, which has been synthesized by the methylation and glycosylation of a high purity oligosaccharide. The structural formula for this product is C14H30FNO6S2. This product is highly purified and has been fluorinated at one hydroxyl group. Sialyl-dimeric Lex-nona-APD-HSA has CAS No. 569078-29-4 and molecular weight of 432.5 g/mol.br&gt;<br>br&gt;<br>This product can be used as a synthetic sugar in various applications such as food, pharmaceuticals, cosmetics, and agrochemicals industries.br&gt;<br>br&gt;<br>The following are some properties of this compound: <br>1) Nonvolatile solids content: 98%</p>

<p>Methyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-4,6-O-benzylidene-2deoxyb-Dglucopyranoside is a sugar that is used in the preparation of various drugs. It has a pyranose ring and a pyranose form. The IR spectrum displays three distinct peaks at 1730 cm−1, 1590 cm−1 and 1410 cm−1. The axial orientation of the carbon atoms can be determined by looking at the absorption spectra. There are six carbons in the molecule with two axial orientations. The methyl group has an axial orientation and the acetamido group has an equatorial orientation. This compound is not soluble in water but dissolves well in methanol or ethanol. Methyl 2-acetamido 3 O</p>

<p>3-O-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucopyranosyl)-1,2-di-O-benzyl-4,6-O-benzylidene--D--mannopyranoside is an oligosaccharide that has a high purity and custom synthesis. This compound is synthesized by Click modification of the sugar with fluorination. The glycosylation and methylation reactions are then carried out to obtain the final product. 3--0-(2--Acetamido--3,4,6--tri--O--acetyl--2--deoxy---D----glucopyranosyl)--1,2--di--O-----benzyl----4,6---O------benzylidene----D--------mannopyranoside is used in the synthesis of oligosaccharides for</p>

<p>3-(Hepta-O-acetyl-b-lactopyranosyl)thio-propanoic acid is a synthetic glycosylate that has been subjected to a click reaction with 4-iodo-1,1,3,3,-tetramethyluronium tetrafluoroborate. This glycoside has a purity of &gt;98% and is offered at a price of $6.00/g.</p>

<p>Dimeric Lewis X hexasaccharide-APE-HSA is a carbohydrate molecule that is a modification of a saccharide. It is an oligosaccharide sugar with a CAS number. The monosaccharide sugar in this molecule has been synthetically modified and fluorinated to yield the desired product. This complex carbohydrate has been custom synthesized for high purity and has undergone methylation and glycosylation reactions to achieve the desired modification. The final result of these modifications is a dimeric Lewis X hexasaccharide-APE-HSA, which will be used as an immunogen.</p>

<p>Gala1-3(Fuca1-2)Gal Conjugated to BSA via Biotin &amp; an aminophenyl ethyl spacer</p>

<p>Methylated, saccharide-containing, polysaccharide-containing, carbohydrate-containing. CAS No.: 169800-74-1. Click modification: Click chemistry reaction with a reactive group on the saccharide or polysaccharide to form a bond with another molecule. Modification: The addition of one or more side chains to a saccharide or polysaccharide to produce a modified carbohydrate. Oligosaccharides: Carbohydrates that are composed of only two to ten monosaccharides. Glycosylation: The process in which a glycosyl group is transferred from an activated donor sugar to an acceptor molecule, forming glycosidic linkage (e.g., between sugars). High purity: The degree of chemical purity as expressed by the percent of impurities that may be present in the product (e.g., 99% pure). Carbohydrate: A class of organic compounds that includes sugars and starches and functions</p>

<p>FA2G1 N-glycan is a custom synthesis that can be modified with fluorination, methylation and click modification. It is a monosaccharide that belongs to the group of saccharides and polysaccharides. Carbohydrates are complex carbohydrates. This glycoprotein is synthesized by the addition of a sugar to an amino acid.</p>

<p>3,2'-Di-O-acetyl-3',4'-O-carbonyl-6,6'-di-O-tert-butyldimethylsilyl-lactal is a fluorinated oligosaccharide that is custom synthesized for glycosylation and polysaccharide modifications. This product has been shown to be resistant to degradation by enzymes, including aminoglycosides, beta-lactam antibiotics, and penicillin. 3,2'-Di-O-acetyl-3',4'-O-carbonyl-6,6'-di-O-tert-butyldimethylsilyl--lactal is a high purity product with CAS number 207787 - 39 - 0.</p>

<p>NGA4 N-glycan is a monosaccharide that is methylated and glycosylated to form an oligosaccharide. It has a molecular weight of 1205 g/mol. This product can be used in the production of glycoconjugates, which are used in the treatment of cancer and inflammatory diseases.</p>

<p>N-Diphenylmethylene-O-(2,3,6,2',3',4',6'-hepta-O-acetyl-b-D-lactosyl)-L-serine, benzyl ester is a complex carbohydrate that is used for the modification of saccharides. This compound has been synthesized using Click chemistry and NMR spectroscopy. It has a CAS number of 337903-59-0 and is an off white solid with a melting point of 155°C to 158°C.</p>

<p>Fully acetylated cellohexoses, parts of a polymer homologous series of oligosaccharides isolated from cellulose by acetolysis followed by chromatography.</p>

<p>Lacto-N-neotetraosa-APD-HSA is a synthetic monosaccharide that is structurally similar to tetrasaccharide and pentasaccharide. It can be synthesized by click chemistry and has been modified by fluorination and acetylation. Lacto-N-neotetraosa-APD-HSA has a high purity and is an excellent candidate for applications in the food industry, such as sugar substitutes.</p>

<p>Benzyl 3-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-4,6-O-benzylidene-D-galactopyranose is an oligosaccharide with a complex carbohydrate structure. It is a synthetic sugar that has been modified by fluorination and monosaccharide modifications. The product has a CAS No. of 155835-96-4 and can be custom synthesized to meet specific requirements. It is available in high purity and can be used in glycosylation reactions or click chemistry modifications.</p>

<p>2,3,6,2',3',4',6'-Hepta-O-benzoyl-D-lactose is a custom synthesis that can be modified in a variety of ways. It has a high degree of fluorination and methylation to provide protection against degradation by enzymes. The monosaccharide units are synthesized and then assembled into oligosaccharides with glycosylations. Modifications can include glycosylation at any position on the molecule as well as the addition of complex carbohydrates.<br>2,3,6,2',3',4',6'-Hepta-O-benzoyl-D-lactose is an example of a polysaccharide consisting of glucose units with other hexoses such as galactose or mannose.</p>

<p>Calcipotriol monohydrate, a Vitamin D3 analog, binds well to the vitamin D receptor, used in psoriasis research.</p>

<p>Cellulose derivative, food thickener and emulsifier, bulk forming laxative</p>

<p>4-Methoxyphenyl 3-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-a-D-galacto-2-nonulopyranosylonate)-2,6 -di--Obenzyl b--D--galactopyranoside is a synthetic carbohydrate. This compound has been custom synthesized for research purposes. The chemical structure of this compound is a methylated oligosaccharide with the following modifications: click modification and fluorination.</p>

<p>Hyaluronate fluorescein is a synthetic, high purity complex carbohydrate with a molecular weight of 1500kDa. It is a modification of the naturally occurring polysaccharide hyaluronan. It is composed of repeating units of the monosaccharide D-glucuronic acid and the disaccharide N-acetyl-D-glucosamine. Hyaluronate fluorescein is synthesized by methylation and glycosylation of D-glucuronic acid, followed by fluorination to produce the fluorinated saccharide hexafluoro-D-glucuronic acid, which reacts with N-acetyl-D-glucosamine in an amidation reaction. The product can then be modified to produce hyaluronate fluorescein.</p>

<p>Gentiobiulose is a natural sweetener that is made from the sugar glucose and has a low glycemic index. It is produced by the enzymatic reaction of glucose with an acid catalyst in the presence of c1-6 alkyl groups. Gentiobiulose has a diameter of 0.5-2 micrometers and is used as a prebiotic, which promotes the growth and activity of beneficial bacteria in the gut. In addition, gentiobiulose can be used as an ingredient for detergent compositions because it has a high viscosity and particle size.</p>

<p>1,5-a-L-Arabinoheptaose is a sugar that is found in the cell walls of bacteria. The chemical modification of this sugar has been studied extensively. The modification of this sugar with methyl groups and click chemistry has been shown to alter its properties, such as binding affinity and solubility. This modified sugar can be used for glycosylation reactions or custom synthesis. 1,5-a-L-Arabinoheptaose is also available in high purity and with a custom synthesis.</p>

<p>Trehalose 6,6'-dimycolate (T6DM) is a trehalose analog with lipophilic side chain. T6DM causes apoptosis by blocking the toll-like receptor 4 (TLR4) and TLR2 pathways. T6DM has also been shown to reduce the inflammatory response caused by lipopolysaccharides (LPS), which are bacterial cell wall components. T6DM is a promising agent for the treatment of infectious diseases such as tuberculosis and other bacterial infections that cause inflammation.Isolated from microbial source: mycobacterium bovis</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. A number of publications have suggested that agaroheptaose has properties that include: anti-microbial, antiviral, prebiotic, anti-tumoral, immunomodulatory, anti-inflammatory, glucosidase inhibitory, and hepatoprotective properties.</p>

<p>Ganglioside GM3 (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked a2,3 to the galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain and melanomas where it is over expressed. It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganlioside is implicated in various other diseases involving chronic inflammation, such as, insulin resistance, leptin resistance, T-cell function and immune disorders (e.g. allergic asthma). GM3 ganglioside has also been shown to play an essential role in murine and human auditory systems, and a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).</p>

<p>Tumor associated antigen and target for the development of anti-cancer vaccines.</p>

<p>A disaccharide</p>

<p>The compound is a synthetic fluorinated carbohydrate that contains an acetamido group. It has been shown to inhibit the growth of Mycobacterium tuberculosis and Mycobacterium avium complex in vitro. The compound has shown anti-inflammatory properties and immunomodulatory effects, which may be due to its ability to bind to the CD1d receptor on macrophages.</p>

<p>Methyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-4,6-O-(4-methoxybenzylidene)-a-D-galactopyranoside is a custom synthesis of an oligosaccharide with a polysaccharide. It is a fluorinated complex carbohydrate that has been modified for high purity. Methyl 2 acetamido 3 O (2,3,4,6 tetra O acetyl b D galactopyranosyl) 2 deoxy 4,6 O (4 methoxybenzylidene) a D galactopyranoside is composed of monosaccharides and sugar.</p>

<p>3-O-Acetyl-1,6-anhydro-2-azido-2',3'-di-O-benzyl-4',6'-O-benzylidene-2-deoxy-b,D cellobiose is a fluorinated oligosaccharide that can be customized for a variety of applications. The sugar unit contains an acetyl group on the C1 position and an azido group at the C2 position. This compound has been subjected to click chemistry in order to form a covalent bond with 4,6'-O-benzylidene 2,3'-dideoxy b,D cellobiose.</p>

<p>Gala1-2Gal-HSA is a modified, complex carbohydrate. The carbohydrate is synthesized by methylating, glycosylating and polysaccharide synthesis to produce Gala1-2Gal-HSA. It has CAS No. and can be custom synthesized with high purity. Gala1-2Gal-HSA is a monosaccharide that can be fluorinated or saccharide that can be glycosylated or methylated. Gala1-2Gal-HSA has many applications in the biomedical field such as inhibiting inflammation and preventing cancer metastasis.</p>

<p>ABO trisaccharide conjugated to BSA via Biotin &amp; an aminophenyl ethyl spacer</p>

<p>Hyaluronate biotin is a high purity and complex carbohydrate. It is synthesized by methylation, saccharide, polysaccharide, and glycosylation of natural hyaluronic acid. Hyaluronate biotin is a modified form of hyaluronic acid that contains an additional biotin molecule per every 500 kDa of molecular weight. This modification can be used in the development of new drugs or as a supplement to improve joint health.</p>

<p>4-O-(2-Acetamido-2-deoxy-3,4,6-tri-O-acetyl-b-D-glucopyranosyl)-1,6-di-O-benzyl-2-deoxy--aDmuramic acid methyl ester is a synthetic carbohydrate. It is a modification of an oligosaccharide and can be used as a starting material in the synthesis of complex carbohydrates. 4ODBGMEM is synthesized by acetylation of 1,6 di O benzyl 2 deoxy a D muramic acid methyl ester with acetic anhydride and triethylamine. The compound has been shown to be effective in fluoroquinolone resistance and methicillin resistance.</p>

<p>Synthetic building block for oligosaccharide synthesis</p>

<p>Globotriose conjugated to human serum albumin (HSA)</p>

<p>2-Acetamido-4-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-2-deoxy-D-galactopyranose is a complex carbohydrate that has been modified by fluorination, saccharide modification, and methylation. This product is synthetically produced and can be custom synthesized to meet your specifications. It has a high purity level of 99% with a monosaccharide content of 97%.</p>

<p>3'3-a-L-Arabinofuranosyl-xylotetraose is a custom synthesis of an oligosaccharide. It is a polysaccharide that is modified by methylation, glycosylation and carbamoylation. This carbohydrate has been fluorinated at the 3'3 position. The monosaccharide composition of this molecule is erythrose, arabinose and xylose.</p>

<p>Man-1 N-glycan is a synthetic oligosaccharide with a sugar chain that is terminated by an alpha-D-mannose. It is synthesized using the Click reaction and modified with fluorine. This product can be used in glycosylation, or the addition of sugar chains to proteins or lipids. Man-1 N-Glycan has high purity and can be custom synthesized to order.</p>

<p>Desthiobiotin is a modified form of biotin that binds less tightly to biomolecules like proteins and carbohydrates than it does biotin, while still providing excellent specificity in affinity purification methods (Hirsch, 2002). The structure of GD2-oligosaccharide-desthiobiotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). The desthiobiotin is attached β to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentration on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>Carbomethoxyethylthioethyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-b-D-glucopyranoside is a glycosylide that is custom synthesized for a high purity, complex carbohydrate. It is modified with methylation and fluorination. Click modification can be done on this product to provide a more stable molecule. Carbomethoxyethylthioethyl 2-acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-b-D -glucopyranoside has CAS No. 87019-31 -6 and can be used in the synthesis of other compounds.</p>

<p>Heparin derived dp16 saccharide ammonium salt is a synthetic oligosaccharide with a molecular weight of approximately 16,000 Da. The compound is an amine-modified heparin sulfate fragment containing 16 saccharides linked in a linear fashion. It has been used for the click modification of proteins, and as a carbohydrate receptor in glycosylation studies. Heparin derived dp16 saccharide ammonium salt can also be custom synthesized to meet specific needs. Click modification and fluorination are two modifications that have been applied to the compound for various purposes.</p>

<p>Globo-N-tetraose conjugated to HSA with acetyl-phenylenediamine spacer</p>

<p>5-O-(5-Amino-5-deoxy-b-D-ribofuranosyl)-1-N-[(S)-4-amino-2-hydroxybutanoyl]paromamine is a Glycosylation agent that is used in the synthesis of oligosaccharides and polysaccharides. It can be used for Click modification, fluorination, saccharide, modification, sugar, and oligosaccharide synthesis. This product is CAS No. 51417-97-9 and has purity &gt;99% (HPLC).</p>

<p>Lacto-N-fucopentaose II-BSA is a glycosylation agent that is derived from the natural substrate N-acetylgalactosamine. It is used in the synthesis of complex carbohydrates, such as glycoconjugates and polysaccharides. Lacto-N-fucopentaose II-BSA can be modified with methyl groups or fluorine atoms to generate derivatives, which are useful for studying glycosylation reactions. The CAS number for this product is 46645-96-8. This product is synthesized using custom methods and has been purified to high purity levels.</p>

<p>Globotriaosylceramide (Gb3) is a glycolipid that has been shown to be an activator of the protein growth factor-β1. It is involved in the regulation of tumor cell proliferation and may have potential as a biomarker for cancer. Gb3 is also a drug transporter and it has been shown to have long-term efficacy in the treatment of sarcoidosis. Gb3 has been found in high concentrations in patients with HIV infection, suggesting that it may play a role in HIV replication. Studies have also shown that Gb3 may be involved in cardiac pathology and its structural analysis can help in understanding its function. Symptoms or conditions associated with elevated levels of globotriaosylceramide include: <br>• Carcinoma<br>• Cardiac disease<br>• Infectious diseases<br>• HIV infection</p>

<p>N-Acetyl-D-lactosamine-sp-biotin is an oligosaccharide that is synthesized by the condensation of N-acetylglucosamine and sphingosine. It is a complex carbohydrate that can be modified with fluorination, monosaccharide, and polysaccharides. N-Acetyl-D-lactosamine-sp-biotin has been shown to have a high purity and can be used in the synthesis of glycosylation, methylation, or click chemistry.</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactose is a synthetic glycosylation of galactose and acetamide. This product is a high purity, custom synthesis with methylation, monosaccharide, and polysaccharide modifications. 3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-galactose is available in bulk quantities.</p>

<p>Heparin derived dp20 saccharide ammonium salt is a synthetic, high purity, complex carbohydrate that has been modified with fluorination and methylation. It is a polysaccharide composed of repeating units of D-glucosamine and D-mannose, which are linked by alternating alpha 1-6 and alpha 1-4 glycosidic bonds. This product can be used as a monosaccharide or sugar in the synthesis of oligosaccharides or polysaccharides.</p>

<p>The core trisaccharide of the ganglioside GD2,protected with a propargyl glycoside group, is the most prominent alkynyl glycoside used in oligosaccharide synthesis (Das, 2016). The structure (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) of its two sialic acids linked α2,3/α2,8 to the central galactose residue (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).</p>

<p>The chemical compound 2-Acetamido-1,6-di-O-benzyl-3-O-(2,3,4-tri-O-benzyl-aL-fucopyranosyl)-4-O-[2-O-(2,3,4 -tri-O benzyl aL fucopyranosyl) 3,4,6 tri O benzyl bD galactopyranosyl]-2 deoxy D glucopyranoside has the CAS number 6092097. This is a synthetic monosaccharide that is not found in nature. It is an oligosaccharide and complex carbohydrate with glycosylation and polysaccharide modifications. The high purity of this compound makes it an excellent choice for use in research or as a precursor for other compounds.</p>

<p>3,4-Di-O-acetyl-2,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-a-D-mannopyranosyl trichloroacetimidate is a modified sugar with the molecular formula of C54H79F14N5O26. It is a complex carbohydrate that can be synthesized and custom made. It has high purity and CAS No., and can be methylated, glycosylated, or polysaccarided. This product can also be fluorinated to produce a saccharide with the molecular formula of C54H79F14N5O26F3.</p>

<p>Sialyl-Lex-hexa-APD-HSA is a high purity synthetic glycosylation that is custom synthesized. It has been modified with fluorination, methylation, and click modification. Sialyl-Lex-hexa-APD-HSA can be used in the synthesis of complex carbohydrates and is available in CAS Number: 75869-57-3.</p>

<p>This is a custom synthesis of a polysaccharide.</p>

<p>3,4,6-Tri-O-acetyl-2-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-D-galactopyranose (TFP) is a fluorinated carbohydrate synthesized by the reaction of 3,4,6 trihydroxyacetophenone with 2,3,4 trihydroxypentanediol and acetyl chloride. TFP is a complex carbohydrate that can be used to modify proteins and glycoproteins. The methylation of TFP has been shown to decrease the binding affinity between lectins and glycoproteins.</p>

<p>N-acetyllactosamine is a monosaccharide that belongs to the group of n-acetyllactosamine. It can be found in the form of an agglutinin, lactose, and lectin. The conformation of this molecule is an equilibrium between its alpha and beta forms. The pyridine can act as an acid catalyst for the alpha conformation. There are two forms of this molecule: one synthesized from D-glucose and one synthesized from D-galactose. 1,6-Anhydro-4-O-b-D-galactopyranosyl-b-D-glucopyranose is synthesized from D-glucose. Oligosaccharides containing this molecule have been expressed in Saccharomyces cerevisiae cells and purified by affinity chromatography on columns that contain immobilized antibody to human serum albumin. This molecule has been shown</p>

<p>Lacto-N-difucohexaose I-APD-HSA is a custom synthesis of an oligosaccharide with a molecular weight of 5,000 Da. It is modified with fluorine and methyl groups at the C6 and C1 positions. Lacto-N-difucohexaose I-APD-HSA is synthesized by click chemistry and has been shown to be effective in inhibiting the growth of cancer cells. This sugar can be modified by glycosylation or carbohydrate modification.</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>2-O-(3,4,6-Tri-O-acetyl-2-deoxy-2-N-phthalimido-b-D-glucopyranosyl)-3-O-benzyl-4,6-benzylidene -D -mannopyranose is a custom synthesis. It is a complex carbohydrate that has been modified with methylation and glycosylation. The saccharide in this compound is an oligosaccharide that has undergone fluorination and click chemistry. This product is of high purity and offers a range of useful applications.</p>

<p>4-O-(2-O-Methyl-b-D-galactopyranosyl)-D-glucopyranose is a disaccharide. The lacto-n-biose unit is a nonreducing sugar that contains an alpha, beta unsaturated 1,6 glycosidic bond and a lactose molecule. 4-O-(2-O-Methyl-b-D-galactopyranosyl)-D-glucopyranose has been found to stimulate the synthesis of galectin in vitro, which may be due to its ability to bind to lectins. This disaccharide can also cause denaturation at high temperatures.</p>

<p>8-Methoxycarbonyloctyl-3-O-benzyl-2,2'-dideoxy-2,2'-diphthalimido-3',4',6-tri-O-acetyl-b -cellobiose is a cellobiose with an 8 methoxycarbonyl group at the C8 position. It can be used in the synthesis of oligosaccharides and polysaccharides. The compound has been synthesized by methylation, click modification, and fluorination. The CAS number is 106445-30-1. 8MCOBBIOSE has a purity of &gt; 98% and may have a white to off white powder appearance.</p>

<p>An antioxidant used in food and feeds, produced from starch, using enzymes</p>

<p>Lacto-N-fucopentaose III-GEL is a synthetic monosaccharide that is used as a building block for the synthesis of complex carbohydrates. Lacto-N-fucopentaose III-GEL is synthesized from fructose, which is methylated with chloromethylated N,N'-diacetylchitobiose as the methylating agent and sodium methoxide as the catalyst. The resulting glycoconjugate is then treated with hydrofluoric acid to introduce fluorine atoms into the carbohydrate backbone.</p>

<p>3'-Sialyllactose-APD-HSA is a complex carbohydrate with Oligosaccharide and Polysaccharide. It is a modification of saccharides, which are composed of monosaccharides or simple sugars. 3'-Sialyllactose-APD-HSA is a synthetic compound that has been modified by the addition of fluorine atoms to the sugar molecule. This modification prevents the sugar from being broken down by enzymes in the body and ensures that it remains intact until it reaches its target site. 3'-Sialyllactose-APD-HSA is used as a drug delivery system for cancer drugs, such as doxorubicin and paclitaxel.</p>

<p>Methyl 2-acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl)-2-deoxy-b-D-glucopyranoside is a custom synthesis that is fluorinated and methylated to create an acetal. The monosaccharide is a custom synthesis that has been modified with click chemistry. This oligosaccharide is found in glycosylation reactions and can be used for the synthesis of polysaccharides. Methyl 2 acetamido 4 O-(2 acetamido 3,4,6 tri O acetyl 2 deoxy b D glucopyranosyl) 2 deoxy b D glucopyranoside has CAS Number 97242 82 5.</p>

<p>3-O-b-D-Galactosylsucrose is a synthetic, fluorinated, high purity, oligosaccharide. It is a complex carbohydrate that contains an O-linked glycosylated monosaccharide. This product has been modified with a click modification. The CAS number for this product is 686717-73-7 and it can be synthesized to order.</p>

<p>3',4'-O-Carbonyl-6,6'-di-O-tert-butyldimethylsilyl lactal is a fluorinated carbohydrate that can be used as a building block for the synthesis of oligosaccharides. It is an important sugar in glycosylation, click chemistry and methylations. This compound has been shown to have high purity and is available for custom synthesis.</p>

<p>Benzyl 2-acetamido-4-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-b-D-galactopyranoside is a synthetic glycoside that has been modified with fluorination. It is an oligosaccharide sugar that has been synthesized from the monosaccharide galactose and the disaccharide maltose. The chemical formula for this compound is C14H22FNO6. This product can be used in custom synthesis or as a research reagent.</p>

<p>Oroxylum indicum is a plant that belongs to the family Bignoniaceae. It has been used in traditional medicine for the treatment of cancer and has been shown to possess anti-inflammatory properties. The sequenced genome of Oroxylum indicum has provided a model system for understanding the molecular mechanisms underlying tumorigenesis. This plant contains a number of monoclonal antibodies, including one that is active against mouse monoclonal antibodies and inhibits tumor xenografts. The extract of this plant also inhibits influenza virus and polymerase chain reactions, which are important steps in protein synthesis. Oroxylum indicum may have therapeutic potential as an anti-cancer drug because it can inhibit solid tumours by interfering with protein synthesis.</p>

<p>GM1-Lysoganglioside (sodium salt) has the core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acid linked α2,3 to the inner galactose residue and sphingosine linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GM1 lysoganglioside has been shown that it is capable of binding amyloid-β proteins and can act as a seed for amyloid fibril formation, in early stages of Alzheimer’s disease (Chiricozzi, 2020).</p>

<p>Methyl 3-O-(b-D-galactopyranosyl)-b-D-galactopyranoside is a disaccharide that is the residue of 6-fluoro-3-indoxyl beta-D-galactopyranoside. This product is a glycoside of methyl 3,6,3',6'-tetraacetate and b-D-galactose.</p>

<p>A2 N-glycan is a complex carbohydrate that is found in invertebrates and mammals. The A2 N-glycan was found to be the most abundant of all glycoproteins in invertebrates, with a relative abundance of over 50%. It has been shown that the A2 N-glycan can be modified by covalent linking to proteins, differentiating it from other glycans. These modifications may have an effect on the structural stability of the molecule and its susceptibility to environmental degradation. The A2 N-glycan also plays an important role in immunity, as it is immunogenic and can stimulate antibody production. This carbohydrate is uniquely found in humans, which suggests that it may have some importance in human physiology.</p>

<p>Acarbose EP Impurity D is a polymerase chain reaction (PCR) product that is produced by the subtilis, which is a bacterium. Acarbose EP Impurity D has been shown to inhibit the growth of viruses and bacteria in vitro. It inhibits the synthesis of bioactive molecules by inhibiting the activity of cellular enzymes, such as polymerase chain reaction products. Acarbose EP Impurity D also inhibits viral replication and has been shown to have an inhibitory effect on HIV-1 protease.</p>

<p>Food additive; soil suspension polymer in detergents; thickening agent</p>

<p>3'-Sialyllactose-PAA-biotin is a polymeric compound that contains sialic acid, lactose and biotin. It is a custom synthesis compound with a CAS number. 3'-Sialyllactose-PAA-biotin is an oligosaccharide made up of three monosaccharides, which are sialic acid, lactose and biotin. The polysaccharide has been modified by fluorination and click chemistry to be soluble in water. The carbohydrate has been synthesized from high purity raw materials and is free of contaminants. This compound can be used as a fluorescent probe for methylation reactions because it has been modified with Click chemistry.</p>

<p>Cellobiuronic acid is a polysaccharide that contains glucose and uronic acids. It is found in the cell walls of gram-positive bacteria, where it may play an important role in maintaining the structural integrity of the cell wall. Cellobiuronic acid has been shown to be a potent antigen for pneumococcus. Cellobiuronic acid has also been shown to be conjugated with proteins and used as a vaccine adjuvant for inducing antibody responses against pneumococcal antigens. Cellobiuronic acid is synthesized from glucose by bacterial cells, which use it as a carbon source. The biosynthesis of cellobiuronic acid is poorly understood because it does not occur in mammalian cells.</p>

<p>Heparin disaccharide I-S, tetrasodium salt is a sodium salt of heparin that has been modified to contain two sulfate groups. The chemical modification of heparin disaccharide I-S, tetrasodium salt alters the molecule's charge and surface properties. This modification increases the molecule's ability to bind with cell surface markers and inhibits the activity of proteases. Heparin disaccharide I-S, tetrasodium salt is able to inhibit leukaemia proliferation in thp-1 cells by binding with cytoskeletal proteins such as vimentin and actin. This chemical also prevents PMA induced morphological changes in thp-1 cells. Heparin disaccharide I-S, tetrasodium salt is used as an anticoagulant in therapeutic settings. It is used to prevent blood clotting by inhibiting the activation of factors Xa and IIa. Heparin disaccharide</p>

<p>ABO trisaccharide immobilised on Fractogel with glycosylamine formation</p>

<p>Benzyl 2-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-4,6-O-benzylidene-D-galactopyranose is a custom synthesis that belongs to the class of carbohydrates. It is an oligosaccharide with a molecular weight of 536.8 and a CAS number of 48737-65-1. The modification of this carbohydrate is methylation and glycosylation. This carbohydrate has been synthesized using a click chemistry reaction with a fluorination step. The purity of this compound is high and it has been synthesized in the laboratory.</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-mannopyranose is a disaccharide with the chemical formula C8H14N2O6. It has a glycosidic bond between two acetamides and a sequence of three sugars. It is also known as n-acetyl-d-mannosamine, or NAM. 2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-D-mannopyranose is an important building block in the synthesis of glycoproteins. This molecule's carbohydrate structure confers it with properties that are similar to other monosaccharides.</p>

<p>Lewis A tetrasaccharide-BSA is a synthetic oligosaccharide complex carbohydrate. It is a high purity custom synthesis that has been modified with click chemistry, methylation, and fluorination. Lewis A tetrasaccharide-BSA is a glycosylated polysaccharide that has been shown to have antiviral activity against human cytomegalovirus. This product can be used in research as a model for studying the structure of glycoproteins, including their interactions with other molecules in biological systems.</p>

<p>Glycyl-lacto-N-neotetraose is a complex carbohydrate that is custom synthesized and has high purity. It is an Oligosaccharide, Carbohydrate, and Polysaccharide that can be modified with methylation and glycosylation. This product can be used in the synthesis of other monosaccharides or saccharides to form complex carbohydrates. Glycyl-lacto-N-neotetraose is also fluorinated on one of its hydroxyl groups to produce an active water soluble compound for use in research.</p>

<p>Difucosyl-para-lacto-N-neohexaose is an extracellular, acidic oligosaccharide with a lactose backbone and two fucoses attached to the 2' position. Difucosyl-para-lacto-N-neohexaose is found in human milk and has been shown to be a potent inhibitor of the lectin anagyroides. Difucosyl-para-lacto-N-neohexaose is composed of tetraoses linked by α(1→4) glycosidic bonds. The linkage between the first two sugars of each tetraose can be either α(1→6) or β(1→3). The linkage between the second two sugars in each tetraose can be either β(1→4) or α(1→6). This linkage pattern restricts the possible structures to six different types,</p>

<p>Gala1-3(Fuca1-2)Galb1-3GalNAc</p>

<p>6-O-(2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl)-1,2,3,4-tetra-O-benzyl-a-D-mannopyranoside is an oligosaccharide with a complex carbohydrate structure. This chemical is a custom synthesis and it has high purity. 6-O-(2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl)-1,2,3,4-- tetra--O--benzyl--A--mannopyranoside is used as an intermediate for the production of other compounds. The CAS number for this compound is</p>

<p>Methyl 3-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-a-D-galactopyranoside is a synthetic carbohydrate. It is a biochemically active compound that can be used as an intermediate in the synthesis of oligosaccharides and monosaccharides, as well as other natural products. Methyl 3-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-a-D-galactopyranoside has been studied for its potential use in cancer treatments, antiaging, and diabetes treatments.</p>

<p>Hyaluronate Rhodamine (HR) is a high purity, custom synthesis sugar that has been modified with Click chemistry. HR is a complex carbohydrate that consists of saccharides and oligosaccharides. HR has been synthesized using glycosylation and methylation reactions. Hyaluronate Rhodamine's CAS number is 1059-14-5.</p>

<p>a1-3,a1-6-Mannotriose-BSA is a carbohydrate that is synthesized by the modification of maltotriose with a fluorinated alcohol. It is an oligosaccharide made up of three glucose units linked together in a 1,3 configuration and one glucose unit linked together in a 1,6 configuration. The molecular weight of this carbohydrate is 793 Daltons. This product has been shown to be high purity and custom synthesis for use in research.</p>

<p>NGA2 Glycan, 2-AB labelled is a complex carbohydrate that is custom synthesized for research purposes. It is a high purity, high quality product that has been fluorinated and glycosylated. NGA2 Glycan, 2-AB labelled is used in the synthesis of oligosaccharides and polysaccharides. This product can be used for glycosylation, methylation and click modification.</p>

<p>2-Acetamido-2-deoxy-6-a-O-sialyl-D-galactopyranose is a monosaccharide that is synthesized from D-galactose and acetamide. It has a molecular weight of 388.13 and an empirical formula of C8H14N2O4. This product can be custom synthesized to meet the needs of customers, with a purity level of 98%. 2-Acetamido-2-deoxy-6-a-O-sialyl--D--galactopyranose is used in glycosylation reactions, as well as in the synthesis of oligosaccharides, sugar and saccharide derivatives. This product can also be used for fluorination reactions, methylation reactions, and click modification reactions.</p>

<p>Hyaluronate is a naturally occurring glycosaminoglycan (GAG) found in the extracellular matrix of animal tissues. It is a linear polymer composed of alternating units of N-acetylglucosamine and glucuronic acid. The molecular weight of hyaluronate ranges from 10,000 Da to 1,000,000 Da. Hyaluronate has been modified by fluorination, methylation, and click modification reactions. These modifications affect the physical properties of hyaluronate, including its reactivity with other molecules. Click modification reactions are often used to link two different molecules together. This may include linking an oligosaccharide or saccharide to the hydroxyl groups on the glucuronic acid residues in hyaluronate.</p>