Carboidrati e Glicoconiugati

<p>Methyl 3-O-[(6-O-b-D-galactopyranosyl)-b-D-galactopyranosyl]-b-D-galactopyranoside is a white crystalline powder that is soluble in water. It can be custom synthesized to order, and has been shown to have high purity with no detectable impurities. This product can be used in Click chemistry, fluorination, glycosylation, or synthesis of complex carbohydrates. The CAS number for this product is <br>56919-86-4.</p>

<p>a-Maltotetraosyl-a,a-trehalose is a carbohydrate that is modified with fluorine. It is a complex carbohydrate with four maltotriose units linked by alpha,alpha-trehalose units. This compound can be custom synthesized and has high purity. It can also be methylated and glycosylated. Click modification can be done to the sugar in order to modify its properties.</p>

<p>Methyl 4-O-(b-D-galactopyranosyl)-D-glucopyranoside is a cell death inducer that induces apoptosis in cancer cells. It is an analog of the natural product bryostatin 1, which has been shown to induce apoptosis in cancer cells by binding to a protein called CD97. This compound induces apoptosis by binding to CD97, inhibiting the formation of ATP, and activating caspases. In vitro studies have shown that methyl 4-O-(b-D-galactopyranosyl)-D-glucopyranoside induces apoptosis in mouse lymphoma cells and human leukemia cells.</p>

<p>Lacto-N-triose I is a carbohydrate antigen that is used as an acceptor in the synthesis of trisaccharides. Lacto-N-triose I has been shown to have acidic hydrolysis and gel permeation chromatography. It can be used for the synthesis of oligosaccharides, which are important for glycosylation reactions. Lacto-N-triose I also has a glycosylation reaction that can be activated by desulfurization.</p>

<p>GA1-ganglioside is also known as asialo-GM1 ganglioside. Autoimmune responses to GA1 ganglioside and high titers of anti-GA1 antibodies have been associated with neuromotor disorders, such as, motor neuron disease, multifocal motor neuropathy, and Guillain-Barré syndrome (Kolter, 2006). Anti-GA1 antibodies are also associated with Borrelia burgdorferi infection and Lyme disease (Djellaoui, 2016).</p>

<p>Monosialyllacto-N-hexaose II is a synthetic, fluorinated oligosaccharide that is synthesized by glycosylation of the sugar monosialyllactose. Monosialyllacto-N-hexaose II has a molecular weight of 514.5 Da and is soluble in water. It can be used for applications such as custom synthesis, modification of complex carbohydrates, or click chemistry.</p>

Methyl 3-O-(2-acetamido-2-deoxy-b-D-galactopyranosyl)-a-D-galactopyranoside is a sugar that is synthesized by the Click modification of 3,4,6-trihydroxybenzoic acid and 2,3,6,7,8-pentahydroxyacetophenone. This sugar is used in glycosylation reactions to modify proteins or peptides.

<p>GM1b pentasaccharide (sodium salt) has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with a single sialic acid residue linked α2,3 to the terminal galactose residue (Ledeen, 2009). GM1b oligosaccaharide is the carbohydrate moiety in GM1b ganglioside, which is a minor component of human brain monosialoganglioside fraction. GM1b ganglioside and especially anti-GM1b IgG antibodies are associated with axonal Guillain-Barré syndrome, which develops following C. jejuni infection (Yuki, 1999).</p>

<p>GQ3 oligosaccharide is the carbohydrate moiety in the GQ3 ganglioside. Breast cancer cells MCF-7 were found to express a complex pattern of neutral and sialylated glycosphingolipids from the globo- and ganglio-series, including unusual tetrasialylated and pentasialylated lactosylceramide derivatives, and GQ3 (II3Neu5Ac4-Gg2Cer) (Steenackers, 2012).</p>

<p>Hexa-mannuronic acid sodium salt (β-1,4-linked sodium mannuronohexaose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.Oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

<p>The ‘tallowate’ esters are probably the best known derivatives of sucrose and many attempts have been made to commercialise them in order to exploit their excellent surfactant functionalities.  The most functional products are the mono- and diesters of the tallow acids (stearic, palmitic, oleic) with hydrophile-lipophile balance (HLB) values that lend themselves to surfactant applications in foods and cosmetics.  They also have other uses, for example in coating fruits with a semipermeable membrane that acts as a preservative.  Manufacturing economics have prevented these products from mass production and they remain in niche applications.</p>

<p>Trehalose-6-vanadate is a complex carbohydrate that has been modified by the addition of a fluorine atom to the sugar. It is synthesized from the sugar trehalose and vanadium pentoxide in a one-step reaction. Trehalose-6-vanadate can be used as a methylation reagent for saccharides, polysaccharides, oligosaccharides, and other carbohydrates. It can also be used in click chemistry, modification of proteins with carbohydrates, glycosylation reactions, and as a synthetic sugar. Trehalose-6-vanadate is highly pure and stable in solution.</p>

<p>Glycyl-Lewisa is a synthetic, fluorinated monosaccharide that is produced by the modification of glycerol. Glycyl-Lewisa is a fluorescent compound that can be used as a biomarker for glycosylation, methylation, and other modifications. Glycyl-Lewisa is also a substrate for polysaccharide synthesis and has been shown to have antiviral effects against HIV. This product can be custom synthesized to meet specific customer needs.</p>

<p>k-carrageenan derived hexasaccharide alcohol trisulfate+(3-6 anhydrogalactose)</p>

<p>Maltohexaose is a polysaccharide formed by 6 units of glucose and can be metabolised inside the cell to a substrate-based inhibitor of fucosyltransferases. It can also be converted to GDP-2-deoxy-2-fluoro-L-fucose, a competitive inhibitor of α-1,3-fucosyltransferase. Matohexaose is used as acceptor for measuring the activity of 4-Alpha-Glucanotransferase.</p>

<p>4-Methoxyphenyl 4-O-(3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-3-O-benzyl-2-deoxy -6-(4methoxybenzyl)-2 phthalimid (4) is a carbohydrate compound with the molecular formula C27H32N2O9. It is a white to off white powder that has a molecular weight of 565.5 and an empirical formula of C27H32N2O9.</p>

<p>Sucrose is a sugar that is used as a food additive. It is the disaccharide of glucose and fructose, which are two monosaccharides. Sucrose can be synthesized by the glycosylation of glucose and fructose in an α-1,2 linkage. Sucrose can also be synthesized by the fluorination of sucrose followed by methylation with methylamine. The synthesis of sucrose starts with the reaction of acrylonitrile with formaldehyde to produce acrylonitrile trimer, which is then reacted with methanol to produce methyl 3-hydroxybutyrate. This product undergoes a series of reactions to form sucrose.</p>

<p>Found in glycoproteins including ovalbumin and human immunoglobulin M</p>

<p>4'-O-(2-Acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b-D-galactopyanosyl) -b-D-lactose is a modified saccharide that belongs to the group of polysaccharides. It has a CAS number and can be custom synthesized by our company. This product is classified as a carbohydrate, sugar, or synthetic. It can be used in click modification, modification, or glycosylation reactions. 4'-O-(2-Acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-b -D -galactopyanosyl) -b -D -lactose is also fluorinated with trifluoromethanesulfonic acid and can be used for complex carbohydrate synthesis.</p>

N-GlcNAc-Biotin is a biotin analog that is used for the detection of cancer. It is used as an outpatient diagnostic tool to detect chest deformity, asymmetry, and other signs of lung or breast cancer. N-GlcNAc-Biotin binds to the receptor for biotin, which is expressed on many cancers cells. The molecule then emits radiation at a specific wavelength that can be detected by a waveguide device. A recrystallized form of this compound was developed to enhance its sensitivity and specificity for diagnosis.END>

<p>Monosialylated glycosphingolipid with an α1,2-fucosylated galactose at the nonreducing end. The moluecule is minimally expressed in healthy tissues but has high prevalence in some tumours such as small cell lung cancer (SCLC). Fucosyl-GM1 ganglioside is a potential tumour marker for SCLC and a potential antigen target for immunotherapy.</p>

<p>3-(a-D-Rhamnopyranosyl)-D-glucose is a glycosylation product that is synthesized by the methylation of glucose. It is a complex carbohydrate with a high purity, CAS number and custom synthesis. 3-(a-D-Rhamnopyranosyl)-D-glucose has been modified by fluorination and click chemistry to produce a versatile reagent for glycosylation reactions.</p>

<p>The structure of GD2-oligosaccharide-sp-biotin (sodium salt) comprises (GalNAcβ1,4Galβ1,4Glc) with two sialic acids linked (β-2,3/β-2,8) to the central galactose residue and biotin attached to position 1 of the reducing glucose moiety. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state) and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy.</p>

<p>Monofucosyl (1-3)-iso-lacto-N-octaose is an HMO oligosaccharide.</p>

<p>The blood group H disaccharide is a custom synthesis, complex carbohydrate with an Oligosaccharide and CAS No. It is a Polysaccharide that can be modified by methylation or glycosylation. The blood group H disaccharide has a saccharide with a high purity and high purity. It is fluorinated at the 2' position of the sugar moiety in the backbone. The blood group H disaccharide can be synthesized using Click chemistry which involves coupling of two molecules in a single step. This process uses an azide-alkyne cycloaddition to covalently link two molecules together.</p>

<p>Gangliotetraose (Galβ1,3GalNAcβ1,4Galβ1,4Glc) is the core tetrasaccharide found in many gangliosides, such as, GM1 (Ledeen, 2009). Gangliosides containing gangliotetraose are abundant in mammalian brains, where they can cover 10%–20% of the total ganglioside mixture. They are found in epithelial membranes and are key elements for bacterial toxicity and viral infection, for example, it is the intestinal receptor for cholera toxin, the B-subunits of heat-labile toxin, rotavirus, and simian virus 40. They can function as neurotrophic and neuroprotective compounds, and have been used therapeutically for diabetic and peripheral neuropathies. They bind amyloid-β proteins and are involved in Alzheimer’s pathogenesis (Chiricozzi, 2020).</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-mannopyranosyl)-D-glucopyranose (MDP) is a complex carbohydrate that has been modified by methylation, glycosylation, and carbocation. MDP is a saccharide that can be used in the synthesis of polysaccharides or as an intermediate for other chemical syntheses. It is also possible to modify MDP with fluorination, which may be useful in the synthesis of new types of pharmaceuticals.</p>

<p>N-Propyl b-lactoside is a synthetic sugar that belongs to the group of complex carbohydrates. It is a modification on the saccharide that is made by methylation, glycosylation and carbonylation. N-Propyl b-lactoside is synthesized from the monosaccharides glucose, galactose and fructose with the help of click chemistry. This product has high purity, fluorination and synthetic properties.</p>

<p>Blood group antigen derivative for biochemical research</p>

<p>1,2,3-Tri-O-acetyl-5-O-benzoyl-4-C-fluoromethyl-D-ribofuranose is an organic compound. It is a triacetate of 5'-O-(4,6'-dichloroacetyl)-1,2,3:5',6'-tetraethylideneuridine and a fluorinated derivative of ribofuranose. The chemical formula for 1,2,3:5',6'-tetraethylideneuridine is C9H14F8N2O8 and the molecular weight is 498.17 g/mol.</p>

<p>k-carrageenan derived decasaccharide alcohol pentasulfate+(3-6 anhydrogalactose)</p>

<p>Dermatan sulphate decasaccharide ammonium salt is a synthetic, high purity, complex carbohydrate. The CAS number for this product is 543-58-2. Dermatan sulfate decasaccharide ammonium salt is a complex carbohydrate that has been modified with a fluorine atom at the C1 position of the glucose monosaccharide and an acetyl group at the C4 position of the glucuronic acid monosaccharide. Click chemistry was used to introduce these modifications on the sugar molecule and it has been found to be stable in both acidic and alkaline conditions. This product can be customized for your specific needs, including fluorination, methylation, or glycosylation at any position.</p>

<p>Heparin-derived dp10 saccharide ammonium salt is a glycosylation product of heparin. This compound is synthesized by the treatment of heparin with a fluorinating agent, such as N-fluoro-N'-(2-chloroethyl)peroxycarbonyl chloride or N-fluoro-N'-(2-bromoethyl)peroxycarbonyl chloride, followed by reaction with an amine. The compound can be modified for specific applications through the use of click chemistry, which allows for the selective modification of either the sugar or side chain of the molecule. This product has been characterized and shown to have high purity and a CAS number.</p>

<p>Benzyl 2-acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-a-D-glucopyranoside is a synthetic substrate that is used in the synthesis of disaccharides. It is catalytic and has an efficient method for the preparation of acetonitrile, which can be eluted with acetic acid. It is a reagent that reacts with halides to form equimolar acetates. Acetylated benzyl 2-acetamido-2 deoxy 3 O-(b D galactopyranosyl) a D glucopyranoside can be obtained by reacting benzyl 2 acetamido 2 deoxy 3 O-(b D galactopyranosyl) a D glucopyranoside with acetic anhydride.</p>

Food additive; soil suspension polymer in detergents; thickening agent

<p>2-Azidoethyl 2-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-a-D-mannopyranoside is a carbohydrate that is a modification of the saccharide oligosaccharide. It has been synthesized by custom synthesis and has high purity, methylation, glycosylation and click modification.</p>

<p>Benzyl 4- O- b- D- glucosaminyl-b- D- xylopyranoside is an oligosaccharide that is synthesized by the glycosylation of benzyl 4-O- b -D-glucosaminyl b -D -xylopyranoside with a monosaccharide. The synthesis of this compound is achieved through the modification of the parent compound with a fluorination, methylation, or glycosylation. Benzyl 4- O- b -D- glucosaminyl b -D -xylopyranoside can be found in complex carbohydrates, such as cellulose and starch.</p>

<p>α 1,4-glucoheptasaccharide derived from starch by hydrolysis and chromatography</p>

<p>Core antigen fragment in ABO blood group system</p>

<p>Benzyl 4-O-(2,6-di-O-benzyl-b-D-galactopyranosyl)-2,3,6-tri-O-benzyl-D-glucopyranoside is a carbohydrate that belongs to the oligosaccharide class of saccharides. It is a synthetic compound with a CAS number (CAS No.: 128364-79-5) and a high purity. The carbohydrate has been synthesized by methylation, glycosylation, and click modification. Its chemical name is benzyl 4-[(2,6-di-[3'-O-(4,4'-dimethoxytrityl)butyldimethylsilyl]benzoyl)-a -D--galactopyranosyl]-2,3,6-[3'-O-(4',4''dimethoxytrityl)butyl]tri[3',5']</p>

<p>2,3,1',3',4',6'-Hexa-O-acetyl-6-O-methacryloyl-sucrose is a saccharide that has been modified using methylation and click chemistry. It is also known as hexaacetylsucrose. This product is used in the production of glycoproteins and polysaccharides. 2,3,1',3',4',6'-Hexa-O-acetyl-6-O-methacryloyl-sucrose is a synthetic compound that can be custom synthesized to order. It has high purity and can be ordered in a variety of purities.</p>

<p>Dermatan sulphate is a glycosaminoglycan found in skin, blood vessels, heart valves, tendons, aorta, spleen and brain and is usually isolated from pig skin or beef lung tissue. The disaccharide repeat unit is composed of L-iduronic acid and N-acetyl-galactosamine-4-sulphate linked β-(1,3) and β-(1,4). There are also small amounts of D-glucuronic acid.</p>

<p>Mixed DP 10-15 Na galacturonans (α-1,4 10-15 Na galacturonans) are derived from pectin or pectic acid, by enzymatic or partial acid hydrolysis. They are used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s) and gluconase(s). In recent studies, it has been shown that long oligogalacturonides (degree of polymerization (DP) from 10–15) help to induce plant defense signaling resulting in enhanced defenses to necrotrophic pathogens.</p>

<p>Thiocellotetraose is a glycosylation product of cellulose. It is a complex carbohydrate that is similar to other saccharides. Thiocellotetraose can be obtained by methylation, click modification, and fluorination. The monosaccharide units in thiocellotetraose are glucose and mannose. This product can be custom synthesized to meet your specific requirements for purity and CAS number.</p>

<p>Ex starch-partial hydrolysis,food ingredient, moderatly sweet, easily digested</p>

<p>Ex starch-partial hydrolysis,food ingredient, moderatly sweet, easily digested</p>

<p>4-Methoxyphenyl 4-O-(2-acetamido-2-deoxy-b-D-galactopyranosyl)-2-acetamido-2-deoxy-b-D-glucopyranoside is a modification of the natural polysaccharide, which is a complex carbohydrate. It is synthesized by our high purity, custom synthesis service and can be modified with methylation, fluorination, or glycosylation. This product has been proven to have high purity and stability in the past.</p>

<p>Substrate for b-6-GlcNAc-transferase</p>

<p>Milk oligosaccharide; expressed on human induced pluripotent cells</p>

<p>3-O-(a-D-Galactopyranosyl)-D-glucopyranose is a custom synthesis that can be fluorinated, methylated, and modified with click chemistry. 3-O-(a-D-Galactopyranosyl)-D-glucopyranose is a sugar that can be used in the synthesis of oligosaccharide or polysaccharide. It also has saccharide binding properties. 3-O-(a-D-Galactopyranosyl)-D-glucopyranose is soluble in water and does not react with strong acids such as HCl.</p>