Derivati del Benzimidazolo e dell’Imidazolo
Il benzimidazolo è un composto costituito da un anello benzenico fuso con un anello imidazolico, una struttura a cinque membri contenente due atomi di azoto. I derivati del benzimidazolo, come l’albendazolo, sono noti per la loro attività antiparassitaria e antifungina, utilizzati nel trattamento delle infezioni parassitarie e di alcune malattie parassitarie negli animali e negli esseri umani. L’imidazolo, invece, è una struttura a cinque membri con due atomi di azoto, presente in vari composti biologicamente attivi. I derivati dell’imidazolo, come il metronidazolo, possiedono proprietà antimicrobiche e antiparassitarie. Questi composti sono impiegati anche nell’industria farmaceutica per il trattamento di infezioni batteriche, malattie parassitarie e alcune infezioni fungine, oltre ad avere applicazioni in chimica organica come catalizzatori.
Presso CymitQuimica, offriamo benzimidazoli e imidazoli ad alta purezza per la ricerca in chimica medicinale, farmacologia e biotecnologia.
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rac N-Demethyl Promethazine-d3 Hydrochloride
CAS:Prodotto controllato<p>Applications Labelled Promethazine (P757000) impurity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Keipert, S., et al.: Pharmazie, 31, 296 (1976),<br></p>Formula:C16H16D3ClN2SColore e forma:NeatPeso molecolare:309.87N-Nitroso Albendazole (mixtures of regional isomers)
Prodotto controllatoFormula:C13H16N4O3SColore e forma:NeatPeso molecolare:616.712N-Nitrosoiminodibenzyl
CAS:Prodotto controllatoFormula:C14H12N2OColore e forma:NeatPeso molecolare:224.26Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity
CAS:Prodotto controllato<p>Applications Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C34H36Cl2N8O5Colore e forma:NeatPeso molecolare:707.61Tiotropium-d6 Bromide
CAS:Prodotto controllatoFormula:C19H16D6BrNO4S2Colore e forma:White To PurplePeso molecolare:478.452-[2-(2-Methyl-4-nitroimidazol-1-yl)ethoxy]ethanol
CAS:Prodotto controllatoFormula:C8H13N3O4Colore e forma:NeatPeso molecolare:215.21β-Ketoglutaric Acid
CAS:<p>Stability Unstable in Solution<br>Applications β-Ketoglutaric Acid is used in the synthesis of benzodiazepine derivatives. Also used in the synthesis of orally available hepatitis C virus polymerase inhibitors.<br>References Jung, D. et al.: Synth. Comm., 29, 1941 (1999); Li, H. et al.: J. Med. Chem., 52, 1255 (2009);<br></p>Formula:C5H6O5Colore e forma:Off White PowderPeso molecolare:146.0984-Hydroxy Midazolam-d5 Methanoate
CAS:Prodotto controllato<p>Applications A labelled metabolite of Midazolam (M343000).<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006),<br></p>Formula:C19H12D5ClFN3O2Colore e forma:NeatPeso molecolare:378.844-Methyl-2-[3-[(1-methylethyl)nitrosoamino]-1-phenylpropyl]phenol
CAS:Prodotto controllatoFormula:C19H24N2O2Colore e forma:NeatPeso molecolare:312.414-Acetoxy Midazolam
CAS:Prodotto controllato<p>Applications A metabolite of Midazolam (M343000).<br></p>Formula:C20H15ClFN3O2Colore e forma:NeatPeso molecolare:383.80(3S)-1-[2-(3-Ethenyl-4-hydroxyphenyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
CAS:Prodotto controllatoFormula:C28H30N2O2Colore e forma:NeatPeso molecolare:426.55N-Nitroso Aryl Lurasidone
CAS:Prodotto controllatoFormula:C11H12N4OSColore e forma:NeatPeso molecolare:248.312,5-Dichlorobenzoyl Cyanide
CAS:Prodotto controllato<p>Applications 2,5-Dichlorobenzoyl Cyanide is a reagent applied for research purposes<br>References Veerareddy, A., et al.: J. Heterocyclic Chem., 51, 1311 (2014)<br></p>Formula:C8H3Cl2NOColore e forma:NeatPeso molecolare:200.022Trimebutine-d9 Maleate Salt
CAS:Prodotto controllato<p>Applications Trimebutine-d9 Maleate Salt, is the labeled analogue of Trimebutine Maleate Salt (T795605), acting as an opioid receptor agonist. Antispasmodic.<br>References Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C22H20D9NO5·C4H4O4Colore e forma:NeatPeso molecolare:512.6N-Carbamoyl Carbamazepine
CAS:Prodotto controllato<p>Impurity Carbamazepine EP Impurity C<br>Applications Carbamazepine (C175840) impurity.<br></p>Formula:C16H13N3O2Colore e forma:NeatPeso molecolare:279.292-Amino-5-benzoyl-1-methylbenzimidazole
CAS:Prodotto controllato<p>Applications Mebendazole (M200500) thermal decomposition product. Mebendazole impurity.<br>References Himmelreich, M., et al.: Aus. J. Pharmaceut. Sci., 6, 123 (1977),<br></p>Formula:C15H13N3OColore e forma:NeatPeso molecolare:251.28Nitroguanidine (Wetted with water >20%)
CAS:Prodotto controllato<p>Applications Nitroguanidine is used in the prediction of heats of detonation of energetic compounds from their molecular structure. It is also used in the synthetic preparation of imidacloprid-d4 (I274992), which is a neonicotinoid.<br> E0<br>References Keshavarz, M.H., et al.: Propellant, Explosives, Pyrotechnics, 37, 93 (2012); Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:CH4N4O2Colore e forma:White To Off-WhitePeso molecolare:104.076-Ethyl-5-fluoropyrimidin-4(3H)-one
CAS:Prodotto controllato<p>Applications A pyrimidine derivative used in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.<br>References Butters, M. et al.: Org. Proc. Res. Dev., 5, 28 (2001); Tong, L. et al.: Zhong. Yao., 8, 280 (2010);<br></p>Formula:C6H7FN2OColore e forma:NeatPeso molecolare:142.13N-Methyl Omeprazole-d3 (Mixture of isomers with the methylated nitrogens of imidazole)
CAS:Prodotto controllato<p>Applications Labelled Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Formula:C18H18D3N3O3SColore e forma:NeatPeso molecolare:362.46
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