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Derivati delle Purine e Pirimidine

Derivati delle Purine e Pirimidine

Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali. Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.

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  • 2,4,5,6-Tetraaminopyrimidine Sulfate

    Prodotto controllato
    CAS:
    <p>Applications Intermediate in the production of Methotrexate<br>References Chiosis, G., et al.: Bioorg. Med. Chem., 10, 3555 (2002), Palanki, M., et al.: J. Med. Chem., 50, 4279 (2007), Zav'yalov, S., et al.: Pharm. Chem. J., 42, 51 (2008),<br></p>
    Formula:C4H8N6·H2O4S
    Colore e forma:Neat
    Peso molecolare:238.22

    Ref: TR-T283940

    25g
    97,00€
    100g
    288,00€
    250g
    643,00€
  • L-Monapterin

    Prodotto controllato
    CAS:
    <p>Applications L-Monapterin is the major pterin compound extracted from Escherichia coli (E.coli) and is used in its detection and identification.<br>References Sugimoto, T. et al.: Hetero., 54, 283 (2001); Ikawa, M. et al.: Phytochem., 38, 1229 (1995);<br></p>
    Formula:C9H11N5O4
    Colore e forma:Light Orange
    Peso molecolare:253.21

    Ref: TR-M505650

    10mg
    325,00€
    100mg
    2.124,00€
  • 1-Methyl Xanthine

    Prodotto controllato
    CAS:
    Formula:C6H6N4O2
    Colore e forma:White
    Peso molecolare:166.14

    Ref: TR-M338575

    1g
    1.330,00€
    100mg
    249,00€
    250mg
    496,00€
  • 3,5-Dinitropyridine

    Prodotto controllato
    CAS:
    <p>Applications 3,5-Dinitropyridine is used as an azabenzyne pyrolytic precursor. The anion radical of 3,5-dinitropyridine aundergoes reversible dimerization reactions.<br>References Winkler, M., et al.: J. Am. Chem. Soc., 126, 6135 (2004); Macias-Ruvalcaba, N., et al.: J. Electroanal. Chem., 600, 294 (2007)<br></p>
    Formula:C5H3N3O4
    Colore e forma:Neat
    Peso molecolare:169.10

    Ref: TR-D441825

    25mg
    361,00€
    100mg
    790,00€
  • 6-hydroxy-5-nitro-1,2,3,4-tetrahydropyrimidine-2,4-dione


    Purezza:98%
    Peso molecolare:173.08399963378906

    Ref: 10-F788415

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  • N-benzyl-7H-purin-6-amine hydrochloride

    CAS:
    Purezza:98%
    Peso molecolare:261.7099914550781

    Ref: 10-F770593

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  • Ref: 10-F090804

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  • N-Benzyl-2-chloro-9-isopropyl-9H-purin-6-amine

    CAS:
    Purezza:98%
    Peso molecolare:301.7799987792969

    Ref: 10-F788470

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  • 4-[6-(2-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine


    Purezza:95.0%
    Peso molecolare:278.31500244140625

    Ref: 10-F511273

    1g
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  • Zolmitriptan-d6 (Major)

    Prodotto controllato
    CAS:
    <p>Stability Hygroscopic<br>Applications A Serotonin 5HTID-receptor agonist.<br>References Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995), Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996), Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)<br></p>
    Formula:C16H15D6N3O2
    Colore e forma:Neat
    Peso molecolare:293.39

    Ref: TR-Z639002

    1mg
    348,00€
    10mg
    2.281,00€
  • N-Methyl Pemetrexed

    Prodotto controllato
    CAS:
    <p>Impurity Pemetrexed EP Impurity A<br>Applications N-Methyl Pemetrexed (Pemetrexed EP Impurity A) is an impurity of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.<br>References Kjell, D.P., et al.: Org. Proc. Res. Develop., 9, 738 (2005);<br></p>
    Formula:C21H23N5O6
    Colore e forma:Neat
    Peso molecolare:441.44

    Ref: TR-M325465

    25mg
    1.967,00€
    2500µg
    294,00€
  • 9-(2-Propenyl)adenine

    Prodotto controllato
    CAS:
    <p>Applications 9-(2-Propenyl)adenine is an N-substituted purine used in the preparation of mesityl dihydroisoxazolyl homo-N-nucleosides.<br>References Thalassitis, A. et al.: Bioorg. Med. Chem. Lett., 19, 6433 (2009); Chiacchio, U. et al.: Tetrahedron, 60, 441 (2004)<br></p>
    Formula:C8H9N5
    Colore e forma:Neat
    Peso molecolare:175.19

    Ref: TR-P768805

    5mg
    247,00€
    50mg
    669,00€
    250mg
    1.490,00€
  • Ref: 10-F728791

    50mg
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  • Ref: 10-F089087

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  • 2-(6-oxo-6,9-dihydro-3H-purin-9-yl)acetic acid

    CAS:
    Purezza:97%
    Peso molecolare:194.14999389648438

    Ref: 10-F609922

    1g
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    20,00€
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    40,00€
  • 1-(Benzo[d][1,2,3]thiadiazol-6-yl)-3-(3,4-dichlorophenyl)urea

    CAS:
    Purezza:98.0%
    Peso molecolare:339.19000244140625

    Ref: 10-F546452

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  • Oxo-Pemetrexed acid

    Prodotto controllato
    CAS:
    Formula:C15H14N4O4
    Colore e forma:Neat
    Peso molecolare:314.3

    Ref: TR-A629910

    5mg
    313,00€
    50mg
    2.055,00€
  • N-Nitroso Zolmitriptan (>80%)

    Prodotto controllato

    Formula:C16H20N4O3
    Purezza:>80%
    Colore e forma:Neat
    Peso molecolare:316.355

    Ref: TR-N598325

    10mg
    275,00€
    100mg
    1.882,00€
  • 2-[3-Carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid

    Prodotto controllato
    CAS:
    <p>Applications 2-[3-Carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid is an impurity of Febuxostat (F229000), an xanthine oxidase/ xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout.<br>References Kadivar, M.H.,e t al.: J. Pharm. Biomed. Anal., 56, 749 (2011);<br></p>
    Formula:C16H17NO5S
    Colore e forma:White Solid
    Peso molecolare:335.37

    Ref: TR-C180600

    10mg
    288,00€
    100mg
    1.928,00€
  • Uric Acid

    CAS:
    <p>Applications Uric Acid is a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.<br>References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006);<br></p>
    Formula:C5H4N4O3
    Colore e forma:Neat
    Peso molecolare:168.11

    Ref: TR-U829200

    1g
    219,00€
    10g
    1.505,00€
  • Ref: 10-F802473

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  • N-phenyl-9H-purin-6-amine

    CAS:
    Purezza:97%
    Peso molecolare:211.22799682617188

    Ref: 10-F372695

    100mg
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  • GR 49336

    Prodotto controllato
    CAS:
    Formula:C12H14N2O4S
    Colore e forma:Neat
    Peso molecolare:282.32

    Ref: TR-G779500

    25mg
    1.549,00€
    2500µg
    227,00€
  • 2-Chloro-4-(4-fluoro-phenyl)-pyrimidine

    CAS:
    Purezza:95.0%
    Peso molecolare:208.6199951171875

    Ref: 10-F231159

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  • Ref: 10-F330430

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  • 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine

    Prodotto controllato
    CAS:
    <p>Stability Hygroscoipic<br>Applications 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine is a major metabolite of Allopurinol (A547300). It is a xanthine oxidase inhibitor.<br>References Pacher, P., et al.: Pharmacol. Rev., 58, 87 (2006); Marro, P., et al.: Brain Res., 650, 9 (1994); Abramov, A., et al.: J. Neurosci., 27, 1129 (2007); Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007);<br></p>
    Formula:C5H4N4O2
    Colore e forma:Off White Solid
    Peso molecolare:152.11

    Ref: TR-D454550

    5g
    798,00€
    10mg
    141,00€
    250mg
    164,00€
  • Tenofovir Alafenamide Fumarate

    Prodotto controllato
    CAS:
    <p>Applications Tenofovir Alafenamide Fumarate is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>
    Formula:C21H29N6O5P·C4H4O4
    Colore e forma:Neat
    Peso molecolare:592.5381

    Ref: TR-T779380

    25mg
    92,00€
    100mg
    101,00€
    500mg
    133,00€
  • Ref: 10-F620806

    1g
    57,00€
    5g
    202,00€
    10g
    330,00€
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    678,00€
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    29,00€
  • Nicotinic Acid-d3 (major)

    Prodotto controllato
    CAS:
    <p>Applications Labelled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term “niacin” has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor).A representative lot contains &gt;20% d4.<br>References Darby, W.J., et al.: Nutr. Rev., 33, 289 (1975), Black, A., et al.: Eur. J. Clin. Nutr., 54, 395 (2000), Cole, T., et al.: Br. Med. J., 320, 1240 (2000), Forshee, R., et al.: J. Nutr., 134, 2733 (2004),<br></p>
    Formula:C6H2D3NO2
    Colore e forma:Neat
    Peso molecolare:126.13

    Ref: TR-N429248

    25mg
    1.523,00€
    2500µg
    230,00€
  • Theophylline-d6

    Prodotto controllato
    CAS:
    <p>Applications Xanthine derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine. Small amounts occur in tea. Bronchodilator.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cohen, J.L., et al.: Anal. Profiles Drug Subs., 4, 466 (1975), Svedmyr, K., et al.: Allergy, 37, 111 (1982),<br></p>
    Formula:C72H6H2N4O2
    Colore e forma:White To Off-White
    Peso molecolare:186.20

    Ref: TR-T343853

    25mg
    2.183,00€
    2500µg
    337,00€
  • Ref: 10-F332611

    100mg
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  • Iopamidol-D3

    Prodotto controllato
    CAS:
    <p>Applications Labelled nonionic radiocontrast medium. Diagnostic aid (radiopaque medium).<br>References Drayer, B., et al.: Am. J. Neuroradiol., 3, 59 (1982), Molyneux, A.J., et al.: Br. J. Radiol., 55, 117 (1982), Sovak, M., et al.: Radiology, 142, 115 (1982), Felder, E., et al.: Anal. Profiles Drug Subs., 17, 115 (1988),<br></p>
    Formula:C17H19D3I3N3O8
    Colore e forma:Off-White
    Peso molecolare:780.10

    Ref: TR-I735602

    5mg
    2.820,00€
    500µg
    418,00€
  • 3-(Formylamino)-1H-pyrazole-4-carboxamide

    Prodotto controllato
    CAS:
    <p>Impurity Allopurinol EP Impurity B / Allopurinol USP Related Compound B<br>Stability Hygroscopic<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxamide (Allopurinol EP Impurity B) is an impurity of Allopurinol (A547300) with inhibitory effects on human hypoxanthine phosphoribosyltransferase.<br>References Krenitzky, T.A. et al.: J. Biol. Chem., 244, 1263 (1969);<br></p>
    Formula:C5H6N4O2
    Colore e forma:White To Off-White
    Peso molecolare:154.127

    Ref: TR-F696750

    250mg
    310,00€
    2500mg
    1.970,00€
  • Ref: 10-F089106

    100mg
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  • 6-Methylpurine

    Prodotto controllato
    CAS:
    <p>Applications 6-Methylpurine (cas# 2004-03-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>
    Formula:C6H6N4
    Colore e forma:Neat
    Peso molecolare:134.14

    Ref: TR-M325950

    50mg
    155,00€
  • 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)

    Prodotto controllato
    CAS:
    <p>Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);<br></p>
    Formula:C17H17N3O
    Colore e forma:White To Off-White
    Peso molecolare:279.34

    Ref: TR-T293715

    10mg
    326,00€
    50mg
    1.292,00€
    100mg
    2.087,00€
  • 4,6-Diphenylpyrimidine

    CAS:
    Purezza:97.0%
    Peso molecolare:232.28599548339844

    Ref: 10-F546414

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  • Orotic Acid-15N2 Monohydrate

    CAS:
    <p>Applications Orotic Acid-15N2 Monohydrate is a labelled analogue of Orotic Acid Monohydrate (O691500(P)), which is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.<br>References Furukawa, S.: PCT Int. Appl. (2009), WO 2009069291 A1<br></p>
    Formula:C5H415N2O4·H2O
    Colore e forma:Neat
    Peso molecolare:177.09

    Ref: TR-O691504

    25mg
    1.927,00€
    2500µg
    299,00€
  • 1-(5-ETHYLPYRIMIDIN-2-YL)PIPERIDIN-4-YL METHANESULFONATE

    CAS:
    Purezza:90.0%
    Peso molecolare:285.3599853515625

    Ref: 10-F530739

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  • 1-METHYL-5-NITRO-2,4(1H,3H)PYRIMIDINEDIONE

    CAS:
    Purezza:95.0%
    Peso molecolare:171.11199951171875

    Ref: 10-F533046

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  • Methotrexate a-Methyl Ester (>90%)

    Prodotto controllato
    CAS:
    <p>Impurity Methotrexate EP Impurity I<br>Applications Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>
    Formula:C21H24N8O5
    Purezza:>90%
    Colore e forma:Neat
    Peso molecolare:468.47

    Ref: TR-M260700

    10mg
    321,00€
    100mg
    2.052,00€
  • 3-[(4,6-Dimethylpyrimidin-2-yl)amino]benzoic acid

    CAS:
    Formula:C13H13N3O2
    Purezza:95.0%
    Colore e forma:Solid
    Peso molecolare:243.266

    Ref: 10-F023725

    1g
    239,00€
    5g
    333,00€
    250mg
    102,00€
  • Methotrexate-d3 Hexaglutamate Trifluoroacetic Acid Salt

    Prodotto controllato
    CAS:
    <p>Applications Methotrexate-d3 Hexaglutamate is the isotope labelled analog of Methotrexate Hexaglutamate (M260745); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>
    Formula:C45H54D3N13O20•x(C2HF3O2)
    Colore e forma:Neat
    Peso molecolare:1103.0311402

    Ref: TR-M260747

    5mg
    1.683,00€
    25mg
    4.128,00€
    500µg
    251,00€
  • 1,3-dioxo-2-pyrimidin-2-ylisoindoline-5-carboxylic acid

    CAS:
    Purezza:95.0%
    Peso molecolare:269.21600341796875

    Ref: 10-F313901

    1g
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  • Regorafenib monohydrate

    CAS:
    Purezza:98%
    Peso molecolare:500.829986572266

    Ref: 10-F863238

    1g
    33,00€
    5g
    99,00€
    10g
    156,00€
    25g
    293,00€
    100g
    751,00€
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    17,00€
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    17,00€
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    17,00€
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  • Methotrexate-d3

    Prodotto controllato
    CAS:
    <p>Applications Labelled Methotrexate (M260675). A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>
    Formula:C20H19D3N8O5
    Colore e forma:Neat
    Peso molecolare:457.46

    Ref: TR-M260677

    1mg
    195,00€
    5mg
    865,00€
    500µg
    133,00€
  • 7-Hydroxy Ondansetron

    CAS:
    <p>Applications A metabolite of Ondansetron.<br>References Colthup, P., et al.: J. Pharm. Sci., 80, 868 (1991), Miyauchi, S., et al.: Pharm. Res.,10, 434 (1993), Ekins, S., et al.: Drug Metab. Dispos., 23, 1274 (1995), Worboys, P., et al.: Xenobiotica, 26, 897 (1996),<br></p>
    Formula:C18H19N3O2
    Colore e forma:Neat
    Peso molecolare:309.362

    Ref: TR-H951150

    1mg
    472,00€
    10mg
    3.176,00€
  • Istradefylline

    CAS:
    <p>Applications Istradefylline is a selective A(2A) antagonist used in the treatment of Parkinson’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dungo, R. et al.: Drugs., 73, 875 (2013); Stoessel, A. et al.: J. Med. Chem., 56, 4580 (2013);<br></p>
    Formula:C20H24N4O4
    Colore e forma:Neat
    Peso molecolare:384.43

    Ref: TR-I927000

    1g
    197,00€
    10mg
    137,00€
    500mg
    162,00€
  • 1,7-Dimethyluric Acid

    Prodotto controllato
    CAS:
    <p>Applications A metabolite of Caffeine.<br>References Kalow, W., et al.: Clin. Pharmacol. Ther., 53, 503 (1993), Sharma, S., et al.: Cancer Res., 54, 5848 (1994), Sugawara, M., et al.: J. Biol. Chem., 275, 16473 (2000), Takeda, M., et al.: J. Pharmacol. Exp. Ther., 302, 666 (2002),<br></p>
    Formula:C7H8N4O3
    Colore e forma:Neat
    Peso molecolare:196.16

    Ref: TR-D479695

    10mg
    147,00€
    25mg
    281,00€
  • Methotrexate Heptaglutamate Trifluoroacetate

    Prodotto controllato
    CAS:
    Formula:C50H64N14O23xC2HF3O2
    Colore e forma:Neat
    Peso molecolare:1229.12

    Ref: TR-M260690

    25mg
    1.705,00€
    2500µg
    254,00€
  • 1,2,3,9-Tetrahydro-4H-carbazol-4-one

    Prodotto controllato
    CAS:
    <p>Applications A carbazole derivative with antimycobacterial activity.<br>References Romeo, G., et al.: Bioorg. Med. Chem., 14, 5211 (2006),<br></p>
    Formula:C12H11NO
    Colore e forma:Beige
    Peso molecolare:185.22

    Ref: TR-T293300

    5g
    92,00€
  • 4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine

    CAS:
    Purezza:95%
    Peso molecolare:211.22799682617188

    Ref: 10-F689948

    100mg
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  • 4-(2,3-dimethoxyphenyl)-6-(furan-2-yl)pyrimidin-2-amine

    CAS:
    Purezza:95.0%
    Peso molecolare:297.3139953613281

    Ref: 10-F524869

    2g
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  • 3-(5-Bromo-2-chloropyrimidin-4-yl)-1H-indole

    CAS:
    Purezza:95.0%
    Peso molecolare:308.55999755859375

    Ref: 10-F461954

    1g
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  • 2-Amino-2′-deoxyadenosine

    CAS:
    Formula:C10H14N6O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:266.261

    Ref: 10-F319576

    5g
    40,00€
    25g
    151,00€
    100g
    494,00€
  • Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate

    CAS:
    Purezza:95.0%
    Colore e forma:Liquid, No data available.
    Peso molecolare:296.3299865722656

    Ref: 10-F213044

    5g
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  • 4-(2-Chloro-9-methyl-9H-purin-6-yl)morpholine

    CAS:
    Purezza:95.0%
    Peso molecolare:253.69000244140625

    Ref: 10-F462154

    100mg
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  • 2-Fluoroadenosine

    Prodotto controllato
    CAS:
    <p>Applications 2-Fluoroadenosine is a fluorinated analog of Adenoside (A280400) nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);<br></p>
    Formula:C10H12FN5O4
    Colore e forma:Neat
    Peso molecolare:285.23

    Ref: TR-F587218

    100mg
    89,00€
    250mg
    91,00€
    500mg
    130,00€
  • N-Desmethoxypropyl Prucalopride

    Prodotto controllato
    CAS:
    <p>Applications N-Desmethoxypropyl Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.<br>References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),<br></p>
    Formula:C14H18ClN3O2
    Colore e forma:Neat
    Peso molecolare:132.201

    Ref: TR-D446943

    100mg
    2.087,00€
  • IMIDOCARB

    CAS:
    Purezza:95.0%
    Colore e forma:Solid
    Peso molecolare:348.4100036621094

    Ref: 10-F390337

    1g
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  • Ref: 10-F657715

    1g
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    2.5g
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  • Ref: 10-F506157

    250mg
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  • 4-Naphthalen-2-yl-pyrimidine-2-thiol

    CAS:
    Peso molecolare:238.05646932

    Ref: 10-F025778

    1g
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  • Tenofovir Monohydrate

    Prodotto controllato
    CAS:
    <p>Stability Hygroscopic<br>Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.<br>References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);<br></p>
    Formula:C9H14N5O4P·H2O
    Colore e forma:Neat
    Peso molecolare:305.23

    Ref: TR-T185533

    1g
    126,00€
    100mg
    93,00€
    250mg
    111,00€
  • Ref: 10-F695014

    1g
    12,00€
    5g
    31,00€
    10g
    46,00€
    25g
    87,00€
    100g
    257,00€
    250mg
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  • Paraxanthine-d3

    Prodotto controllato
    CAS:
    <p>Applications Paraxanthine-d3, is the labeled analogue of Paraxanthine (P192500), an adenosine receptor ligand and a major metabolite of caffeine.<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>
    Formula:C72H3H5N4O2
    Colore e forma:Neat
    Peso molecolare:183.18

    Ref: TR-P192503

    1mg
    379,00€
    10mg
    2.577,00€
  • 4,6-Dichloro-2,5-diphenylpyrimidine

    CAS:
    Purezza:95.0%
    Colore e forma:Solid
    Peso molecolare:301.1700134277344

    Ref: 10-F329633

    25g
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  • 1,3-Dimethyladamantane

    CAS:
    <p>Impurity Memantine Related Compound A (1,3-Dimethyladamantane)<br>Applications 1,3-Dimethyladamantane is a dimethylated adamantane derivative. Memantine impurity A. Memantine Related Compound A (1,3-Dimethyladamantane).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>
    Formula:C12H20
    Colore e forma:Neat
    Peso molecolare:164.29

    Ref: TR-D460778

    1g
    264,00€
    10g
    752,00€
    25g
    1.597,00€
  • Pyrimidine, 2-(2-methylphenyl)-

    CAS:
    Purezza:97%
    Peso molecolare:170.21499633789062

    Ref: 10-F603150

    1g
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  • 2-[(2-Amino-6-chloro-4-pyrimidinyl)amino]ethanol

    CAS:
    Purezza:95.0%
    Colore e forma:Solid, Yellow powder
    Peso molecolare:188.6199951171875

    Ref: 10-F075086

    1g
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  • Ethyl 2-Chloracetoacetate

    CAS:
    <p>Applications Ethyl 2-Chloracetoacetate is used in the preparation of oxazoles and thiazoles as agonists for peroxisome proliferator-activated receptor δ. It is also used to synthesize dimethylimidazothiadiazolecarbohydrazides with anticancer activities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sznaidman, M., et al.: Bioorg. Med. chem. Lett., 13, 1517 (2003); Terzioglu, N., et al.: Eur. J. Med. Chem., 38, 781 (2003)<br></p>
    Formula:C6H9ClO3
    Colore e forma:Neat
    Peso molecolare:164.59

    Ref: TR-E903485

    5g
    93,00€
  • N-Demethyl Ondansetron

    CAS:
    <p>Applications A metabolite of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bayliss, M., et al: Xenobiotica, 24, 231 (1994), Atkins, W., et al.: J. Biol. Chem., 277, 33258 (2002), De Graaf, I., et al.: Drug Metab. Dispos., 30, 1129 (2002),<br></p>
    Formula:C17H17N3O
    Colore e forma:White To Brown
    Peso molecolare:279.34

    Ref: TR-D231170

    50mg
    190,00€
    100mg
    262,00€
    250mg
    600,00€
  • 5-Bromo-N-(diphenylmethylene)-2-pyrimidinamine

    CAS:
    Purezza:95+%
    Peso molecolare:338.2080078125

    Ref: 10-F632670

    1g
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  • 7-BROMO-2-(3-(PYRIMIDIN-2-YL)PHENETHYL)ISOINDOLIN-1-ONE

    CAS:
    Purezza:95.0%
    Peso molecolare:394.2720031738281

    Ref: 10-F332625

    50mg
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  • Pyrimidine

    Prodotto controllato
    CAS:
    Formula:C4H4N2
    Colore e forma:Colourless
    Peso molecolare:80.09

    Ref: TR-P997330

    1g
    102,00€
    5g
    212,00€
  • Ondansetron-d3

    Prodotto controllato
    CAS:
    <p>Applications Ondansetron-d3 is a labeled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>
    Formula:C18H16D3N3O
    Colore e forma:Neat
    Peso molecolare:296.38

    Ref: TR-O655007

    1mg
    271,00€
    10mg
    1.765,00€
  • Ref: 10-F223913

    250mg
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  • 8-(2-Fluorophenyl)-9H-purine

    CAS:
    Purezza:95.0%
    Peso molecolare:214.2030029296875

    Ref: 10-F239977

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  • 3-Descyano Febuxostat

    Prodotto controllato
    CAS:
    <p>Applications 3-Descyano Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Kadivar, M.H., et. al.: J. Pharmaceut. Biomed. Anal., 56, 749 (2011); Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>
    Formula:C15H17NO3S
    Colore e forma:Neat
    Peso molecolare:291.37

    Ref: TR-D289705

    10mg
    243,00€
    100mg
    1.663,00€
  • Ref: 10-F546272

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  • Sulbutiamine

    Prodotto controllato
    CAS:
    <p>Applications Sulbutiamine (isobutyryl thiamine disulfide) is a lipophilic derivative of thiamine used for the treatment of asthenia and other related pathological conditions. Sulbutiamine is available over-the-counter in several countries as a component of nutritional supplements.<br>References Micheau, J., et al.: Pharmacol. Biochem. Behav., 23, 195 (1985), Bettendorff, L., et al.: Biochem. Pharmacol., 40, 2557 (1990), van Reeth, O., et al.: Drugs Today, 35, 187 (1999),<br></p>
    Formula:C32H46N8O6S2
    Colore e forma:Off White
    Peso molecolare:702.89

    Ref: TR-S689250

    1g
    113,00€
    5g
    187,00€
    50g
    351,00€
  • Ref: 10-F546540

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  • 2-(1-naphthyl)pyrimidine-5-carbaldehyde

    CAS:
    Purezza:95.0%
    Colore e forma:Solid
    Peso molecolare:234.25799560546875

    Ref: 10-F309061

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  • Fmoc N-Hydroxysuccinimide Ester

    CAS:
    <p>Stability Moisture Sensitive<br>Applications Used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Heidenreich, O., et al.: J. Biol. Chem., 269, 2131 (1994), Kothe, U., et al.: Anal. Biochem., 356, 148 (2006), Thakkar, A., et al.: Anal. Chem., 78, 5935 (2006),<br></p>
    Formula:C19H15NO5
    Colore e forma:Neat
    Peso molecolare:337.33

    Ref: TR-F634000

    25g
    113,00€
    100g
    137,00€
    250g
    226,00€
  • Methotrexate a-tert-Butyl Ester

    Prodotto controllato
    CAS:
    <p>Applications Methotrexate α-tert-Butyl Ester is an intermediate to the synthesis of folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Yoshii, T., et al.: J. Am. Chem. Soc., 136, 16635 (2014);<br></p>
    Formula:C24H30N8O5
    Colore e forma:Neat
    Peso molecolare:510.546

    Ref: TR-M260750

    25mg
    346,00€
    100mg
    1.040,00€
  • 2-Chloro Adenosine

    CAS:
    <p>Applications A selective A1-adenosine receptor agonist. Induces apoptosis.<br>References Evans, et al.: Neurosci. Lett., 83, 287 (1987), Szondy, Z.: Biochem. J., 304, 877 (1994)<br></p>
    Formula:C10H12ClN5O4
    Colore e forma:Off-White
    Peso molecolare:301.69

    Ref: TR-C364000

    25g
    544,00€
    10mg
    105,00€
    50mg
    122,00€
  • 5-Hydroxymethylcytosine

    CAS:
    Purezza:90.0%
    Colore e forma:Solid
    Peso molecolare:141.1300048828125

    Ref: 10-F208887

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  • 4-Chloro-5,6-dimethyl-2-(trifluoromethyl)-pyrimidine

    CAS:
    Formula:C7H6ClF3N2
    Purezza:97.0%
    Colore e forma:Liquid
    Peso molecolare:210.58

    Ref: 10-F004400

    250mg
    137,00€
  • Isoguanosine Hydrate

    Prodotto controllato
    CAS:
    <p>Applications A useful synthetic intermedate. A naturally occuring, biologically active isomer of guanosine. Reported to stimulate the accumulation of cyclic-AMP in the brain. It is an inhibitor of IMP pyrophosphorylase, and its 5’-di and -tri-phosphates inhibit glutamic acid dehydrogenase. May contain approximately 0.6 moles of water.<br>References Divakar, K.J., et al.: J. Chem. Soc. Perkin Trans., 1, 771 (1991), Montsch, H.H., et al: Biochemistry, 14, 5593 (1975), Hagen, C.: Biochim. Biophys. Acta., 293, 105 (1973), Huang, M., et al.: J. Med. Chem., 15, 462 (1972)<br></p>
    Formula:C10H13N5O5·H2O
    Colore e forma:Neat
    Peso molecolare:301.26

    Ref: TR-I819500

    10mg
    118,00€
    50mg
    445,00€
    100mg
    747,00€
  • Chloromethyl Ethyl Carbonate

    Prodotto controllato
    CAS:
    <p>Applications A reagent used in the preparation of hepatitis C virus NS3 protease inhibitors and PMPA prodrugs with antiretroviral activity.<br>References Sheng, X. et al.: Bioorg, Med. Chem. Lett., 169, 3453 (2009); Arimilli, M.N. et al.: Antiviral Chem. Chemother., 8, 557 (1997);<br></p>
    Formula:C4H7ClO3
    Colore e forma:Colourless Oily
    Peso molecolare:138.55

    Ref: TR-C369300

    1g
    397,00€
    10g
    2.277,00€
    500mg
    302,00€
  • Ref: 10-F495263

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  • 6-Methyl-2-methylsulfanyl-3H-pyrimidin-4-one

    CAS:
    Purezza:98.0%
    Colore e forma:Solid, Crystalline
    Peso molecolare:156.1999969482422

    Ref: 10-F046352

    5g
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    109,00€
  • 4-(3,4-dimethylphenyl)-6-(3-methylphenyl)pyrimidin-2-amine

    CAS:
    Purezza:95.0%
    Peso molecolare:289.3819885253906

    Ref: 10-F524845

    2g
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  • 4-(4-bromophenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine

    CAS:
    Purezza:95.0%
    Peso molecolare:354.2510070800781

    Ref: 10-F524847

    2g
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  • 2-(4-Chlorophenyl)amino-4-phenylpyrimidine

    CAS:
    Purezza:95.0%
    Colore e forma:Solid, No data available.
    Peso molecolare:281.739990234375

    Ref: 10-F047488

    1g
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  • 7-Hydroxy Memantine Hydrochloride

    Prodotto controllato
    CAS:
    <p>Stability Hygroscopic<br>Applications A metabolite of Memantine (M218000), used for the treatment of neurological disorders.<br>References Eiichi, K., et al.: Chem. Pharm. Bull., 33, 4680 (1985),<br></p>
    Formula:C12H21NO·ClH
    Colore e forma:Neat
    Peso molecolare:231.76

    Ref: TR-H944700

    5mg
    280,00€
    25mg
    1.201,00€
    50mg
    1.846,00€
  • Ref: 10-F610081

    100mg
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  • Ref: 10-F495927

    1g
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  • Ref: 10-F635743

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  • 4-(1-benzofuran-2-yl)-2-hydrazinopyrimidine

    CAS:
    Purezza:95.0%
    Peso molecolare:226.23899841308594

    Ref: 10-F313223

    1g
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