Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8901 prodotti di "Derivati delle Purine e Pirimidine"
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Ref: 10-F239266
1gPrezzo su richiesta5gPrezzo su richiesta25gPrezzo su richiesta250mgPrezzo su richiesta7-Hydroxy Memantine Hydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A metabolite of Memantine (M218000), used for the treatment of neurological disorders.<br>References Eiichi, K., et al.: Chem. Pharm. Bull., 33, 4680 (1985),<br></p>Formula:C12H21NO·ClHColore e forma:NeatPeso molecolare:231.765-Acetylamino-6-formylamino-3-methyluracil
CAS:Prodotto controllato<p>Applications Metabolite of Caffeine (C080100).<br>References Grant, D.M., et al.: Clin. Pharm. and Ther., 33, 591 (1983),<br></p>Formula:C8H10N4O4Colore e forma:Light Yellow SolidPeso molecolare:226.19Zolmitriptan-d6 (Major)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A Serotonin 5HTID-receptor agonist.<br>References Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995), Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996), Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)<br></p>Formula:C16H15D6N3O2Colore e forma:NeatPeso molecolare:293.394-Hydroxy-3,5-diiodobenzyl Alcohol
CAS:Prodotto controllato<p>Applications Intermediate in the production of Thyroxine<br></p>Formula:C7H6I2O2Colore e forma:NeatPeso molecolare:375.93Methotrexate γ-Methyl Ester
CAS:Prodotto controllato<p>Impurity Methotrexate EP Impurity H<br>Applications Methotrexate γ-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C21H24N8O5Colore e forma:NeatPeso molecolare:468.471,3,7-Trimethyluric Acid-d3
CAS:Prodotto controllato<p>Stability Store in freezer<br>Applications A caffeine metabolite.<br>References Regal, K.A., et al.: J. of Chromatography B, 708, 75 (1998)<br></p>Formula:C82H3H7N4O3Colore e forma:NeatPeso molecolare:213.212,4-Pteridinediamine-6-methanol
CAS:Prodotto controllatoFormula:C7H8N6OColore e forma:NeatPeso molecolare:192.184-(3-fluorophenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:271.309997558593755-Cyclopropyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
CAS:Formula:C7H8N2OSPurezza:95.0%Colore e forma:SolidPeso molecolare:168.217-Methyl Memantine Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 7-Methyl Memantine is an impurity of Memantine (HCl salt, M218000) which is used as an antiparkinsonian and antispasmodic.<br>References Rohde, H., et al.: Fortschr. Med., 100, 2023 (1982), Kornhuber, J., et al.: Eur. J. Pharmacol., 166, 589 (1989), Gortelmeyer, R. and Erbler, H.: Arzneimittel-Forsch., 42, 904 (1992)<br></p>Formula:C13H23N·ClHColore e forma:White SolidPeso molecolare:229.792-Isopropyl-pyrimidine-5-carboxylic acid
CAS:Formula:C8H10N2O2Purezza:95.0%Colore e forma:SolidPeso molecolare:166.18Tenofovir Phosphate Diammonia Salt, >90%
CAS:Prodotto controllato<p>Applications Tenofovir Phosphate Diammonia Salt is a metabolite of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Michelson, A.M., et al.: Biochim. Biophys. Acta, 91, 1 (1964); Rosenberg, I., et al.: Collect. Czeck. Chem. Commun., 50, 1507 (1985); Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005),; Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006); Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formula:C9H21N7O7P2Purezza:>90%Colore e forma:NeatPeso molecolare:401.252-[(2-Amino-6-chloro-4-pyrimidinyl)amino]ethanol
CAS:Purezza:95.0%Colore e forma:Solid, Yellow powderPeso molecolare:188.61999511718752-Chloro Adenosine
CAS:<p>Applications A selective A1-adenosine receptor agonist. Induces apoptosis.<br>References Evans, et al.: Neurosci. Lett., 83, 287 (1987), Szondy, Z.: Biochem. J., 304, 877 (1994)<br></p>Formula:C10H12ClN5O4Colore e forma:Off-WhitePeso molecolare:301.69Methotrexate a-tert-Butyl Ester
CAS:Prodotto controllato<p>Applications Methotrexate α-tert-Butyl Ester is an intermediate to the synthesis of folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.<br>References Yoshii, T., et al.: J. Am. Chem. Soc., 136, 16635 (2014);<br></p>Formula:C24H30N8O5Colore e forma:NeatPeso molecolare:510.546Tenofovir Isopropyl Ethyl Diester
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tenofovir Disopropyl Ethyl Diester is an impurity of Tenofovir (T018500), an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C18H28N5O10PColore e forma:NeatPeso molecolare:505.426-Methyl-2-methylsulfanyl-3H-pyrimidin-4-one
CAS:Purezza:98.0%Colore e forma:Solid, CrystallinePeso molecolare:156.19999694824223-Descyano Febuxostat
CAS:Prodotto controllato<p>Applications 3-Descyano Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Kadivar, M.H., et. al.: J. Pharmaceut. Biomed. Anal., 56, 749 (2011); Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C15H17NO3SColore e forma:NeatPeso molecolare:291.37Doxofylline
CAS:Prodotto controllato<p>Applications Doxofylline is a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence supporting the effects of Doxofylline in the treatment of lung diseases.<br>References Franzone, J., et al.: Drugs Exp. Clin. Res., 14, 479 (1988), Nicholson, C., et al.: Pulm. Pharmacol., 7, 1 (1994), Sullivan, P., et al.: Lancet, 343, 1006 (1994),<br></p>Formula:C11H14N4O4Colore e forma:NeatPeso molecolare:266.25N4-Methylene Zolmitriptan
CAS:Prodotto controllato<p>Applications Zolmitriptan (Z639000) impurity.<br></p>Formula:C17H21N3O2Colore e forma:NeatPeso molecolare:299.37Ethyl 3-Amino-4-pyrazolecarboxylate
CAS:Prodotto controllatoFormula:C6H9N3O2Colore e forma:White To BeigePeso molecolare:155.151-Methyluric Acid-d3
CAS:Prodotto controllato<p>Applications A labelled metabolite of Theophylline.<br>References Chen, Y., et al.: Clin. Exper. Pharmacol. Physiol., 36, 828 (2009), Yu, C., et al.: J. Bacteriol., 191, 4624 (2009), Jetter, A., et al.: Eur. J. Clin. Pharmacol., 65, 411 (2009),<br></p>Formula:C62H3H3N4O3Colore e forma:NeatPeso molecolare:185.16N-Nitroso Zolmitriptan (>80%)
Prodotto controllatoFormula:C16H20N4O3Purezza:>80%Colore e forma:NeatPeso molecolare:316.355N-(3-Chloro-4-(((2-(methylamino)-6-(pyridin-2-yl)pyrimidin-4-yl)amino)methyl)phenyl)methanesulfonamide
CAS:Purezza:98.0%Peso molecolare:418.8999938964844Ref: 10-F546745
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta(R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine
CAS:Prodotto controllato<p>Applications A acyclic phosphonate nucleotide.<br></p>Formula:C13H22N5O4PColore e forma:White SolidPeso molecolare:343.32Urea-urethane Compound (~85%)
CAS:Prodotto controllato<p>Applications Urea-urethane Compound is a reaction product of 4,4'-sulfonylbis[benzenamine] and 2,4-TDI.<br></p>Formula:C42H36N6O8SPurezza:~80%Colore e forma:NeatPeso molecolare:784.84Zeatin
CAS:<p>Applications Zeatin belongs to the family of plant-growth hormones called cytokinins and it can be used for agricultural use as agrochemicals for increasing crop yields and regulate various aspects of plant growth and development.<br>References Koprna, R., et al.: Bioorgan. Med. Chem., 24, 484-492 (2016)<br></p>Formula:C10H13N5OColore e forma:White To Off-WhitePeso molecolare:219.24N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:277.33099365234375rac Tenofovir-d6
CAS:Prodotto controllato<p>Applications A deuterated acyclic phosphonate nucleotide analogue, reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C92H6H8N5O4PColore e forma:Off White SolidPeso molecolare:293.251-Bromo-3-methyladamantane
CAS:Prodotto controllatoFormula:C11H17BrColore e forma:NeatPeso molecolare:229.16Methotrexate-d3 Heptaglutamate Trifluoroacetate
CAS:Prodotto controllatoFormula:C50H61D3N14O23xC2HF3O2Colore e forma:NeatPeso molecolare:1232.1422-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS:Purezza:95.0%Peso molecolare:259.31298828125Paraxanthine-d3
CAS:Prodotto controllato<p>Applications Paraxanthine-d3, is the labeled analogue of Paraxanthine (P192500), an adenosine receptor ligand and a major metabolite of caffeine.<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>Formula:C72H3H5N4O2Colore e forma:NeatPeso molecolare:183.184,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
CAS:Purezza:98.0%Peso molecolare:349.1700134277344Ethyl Tosylate
CAS:<p>Applications Ethyl Tosylate (cas# 80-40-0) is a compound useful in organic synthesis.<br></p>Formula:C9H12O3SColore e forma:NeatPeso molecolare:200.266-O-Methyl Guanosine
CAS:Prodotto controllato<p>Applications A guanine derivative that acts as modulators of GTPases and modulator-resistant enzymes; used in drug design and target validation.<br>References Goth-Goldstein, R., et al.: Cancer Res., 40, 2623 (1980), Nakabeppu, Y., et al.: J. Biol. Chem., 259, 13723 (1984), Modrich, P., et al.: Science, 266, 1959 (1994),<br></p>Formula:C11H15N5O5Colore e forma:WhitePeso molecolare:297.271-(3-(BENZO[D]THIAZOL-2-YL)-4-HYDROXYPHENYL)-3-PHENYLUREA
CAS:Purezza:95.0%Peso molecolare:361.42001342773441,2,3,9-Tetrahydro-4H-carbazol-4-one
CAS:Prodotto controllato<p>Applications A carbazole derivative with antimycobacterial activity.<br>References Romeo, G., et al.: Bioorg. Med. Chem., 14, 5211 (2006),<br></p>Formula:C12H11NOColore e forma:BeigePeso molecolare:185.22Tenofovir Monohydrate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.<br>References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);<br></p>Formula:C9H14N5O4P·H2OColore e forma:NeatPeso molecolare:305.23Tri-o-tolyl-Phosphine Oxide
CAS:Prodotto controllato<p>Impurity Eletriptan Impurity 14<br>Applications Tri-o-tolyl-Phosphine Oxide (Eletriptan Impurity 14) is an impurity of Eletriptan, a selective serotonin 5-HT1B and 5-HT1D receptor agonist and used to treat migraines.<br>References Willems, E., et al.: Arch. Pharmacol., 358, 212 (1998); Napier, C., et al.: Eur. J. Pharmacol., 368, 259 (1999); Goadsby, P.J., et al.: Neurology, 54, 156 (2000)<br></p>Formula:C21H21OPColore e forma:NeatPeso molecolare:320.365(6-Benzhydryloxycarbonylamino-purin-9-yl)-acetic acid
CAS:Purezza:97.0%Colore e forma:SolidPeso molecolare:403.398010253906251-Methyluric Acid
CAS:Prodotto controllato<p>Applications A metabolite of Theophylline.<br>References Chen, Y., et al.: Clin. Exper. Pharmacol. Physiol., 36, 828 (2009), Yu, C., et al.: J. Bacteriol., 191, 4624 (2009), Jetter, A., et al.: Eur. J. Clin. Pharmacol., 65, 411 (2009),<br></p>Formula:C6H6N4O3Colore e forma:Light Yellow To Light BrownPeso molecolare:182.14Istradefylline
CAS:<p>Applications Istradefylline is a selective A(2A) antagonist used in the treatment of Parkinson’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dungo, R. et al.: Drugs., 73, 875 (2013); Stoessel, A. et al.: J. Med. Chem., 56, 4580 (2013);<br></p>Formula:C20H24N4O4Colore e forma:NeatPeso molecolare:384.431,7-Dimethyluric Acid
CAS:Prodotto controllato<p>Applications A metabolite of Caffeine.<br>References Kalow, W., et al.: Clin. Pharmacol. Ther., 53, 503 (1993), Sharma, S., et al.: Cancer Res., 54, 5848 (1994), Sugawara, M., et al.: J. Biol. Chem., 275, 16473 (2000), Takeda, M., et al.: J. Pharmacol. Exp. Ther., 302, 666 (2002),<br></p>Formula:C7H8N4O3Colore e forma:NeatPeso molecolare:196.164-(2-Chloropyrimidin-4-yl)morpholine
CAS:Formula:C8H10ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:199.641,7-Dimethyluric Acid-d3
CAS:Prodotto controllatoFormula:C7H5D3N4O3Colore e forma:Off-White To Light GreyPeso molecolare:199.18Methyl 4-((6-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidin-4-yl)oxy)benzoate
CAS:Purezza:97.0%Peso molecolare:324.3399963378906Methotrexate-d3
CAS:Prodotto controllato<p>Applications Labelled Methotrexate (M260675). A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C20H19D3N8O5Colore e forma:NeatPeso molecolare:457.46Methotrexate a-Methyl Ester (>90%)
CAS:Prodotto controllato<p>Impurity Methotrexate EP Impurity I<br>Applications Methotrexate α-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C21H24N8O5Purezza:>90%Colore e forma:NeatPeso molecolare:468.47Ormetoprim
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications It is a potent and selective inhibitor of bacterial dihydrofolate reductase, the enzyme responsible for the NADPH-dependent reduction of 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate. Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Formula:C14H18N4O2Colore e forma:Off-WhitePeso molecolare:274.32Febuxostat n-Butyl Isomer
CAS:Prodotto controllato<p>Applications Febuxostat n-butyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C16H16N2O3SColore e forma:NeatPeso molecolare:316.37Orotic Acid-15N2 Monohydrate
CAS:<p>Applications Orotic Acid-15N2 Monohydrate is a labelled analogue of Orotic Acid Monohydrate (O691500(P)), which is used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.<br>References Furukawa, S.: PCT Int. Appl. (2009), WO 2009069291 A1<br></p>Formula:C5H415N2O4·H2OColore e forma:NeatPeso molecolare:177.09(2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:311.29800415039065-(3,3-Dimethyl-ureido)-naphthalene-1-sulfonylchloride
CAS:Formula:C13H13ClN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:312.771-Bromo-3,5-dimethyladamantane
CAS:Prodotto controllato<p>Applications 1-Bromo-3,5-dimethyladamantane (cas# 941-37-7) is a compound useful in organic synthesis.<br></p>Formula:C12H19BrColore e forma:ColourlessPeso molecolare:243.184-(5-methylthiophen-2-yl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:273.3699951171875Theophylline-d6
CAS:Prodotto controllato<p>Applications Xanthine derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine. Small amounts occur in tea. Bronchodilator.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cohen, J.L., et al.: Anal. Profiles Drug Subs., 4, 466 (1975), Svedmyr, K., et al.: Allergy, 37, 111 (1982),<br></p>Formula:C72H6H2N4O2Colore e forma:White To Off-WhitePeso molecolare:186.201-(2-Amino-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl)-3-(tert-butyl)urea
CAS:Purezza:95.0%Peso molecolare:396.450988769531254-(Tert-butyl)-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)benzamide
CAS:Purezza:98%Peso molecolare:438.54998779296875Nicotinic Acid-d3 (major)
CAS:Prodotto controllato<p>Applications Labelled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term “niacin” has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor).A representative lot contains >20% d4.<br>References Darby, W.J., et al.: Nutr. Rev., 33, 289 (1975), Black, A., et al.: Eur. J. Clin. Nutr., 54, 395 (2000), Cole, T., et al.: Br. Med. J., 320, 1240 (2000), Forshee, R., et al.: J. Nutr., 134, 2733 (2004),<br></p>Formula:C6H2D3NO2Colore e forma:NeatPeso molecolare:126.134,6-Dihydroxypyrazolo[3,4-d]pyrimidine
CAS:Prodotto controllato<p>Stability Hygroscoipic<br>Applications 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine is a major metabolite of Allopurinol (A547300). It is a xanthine oxidase inhibitor.<br>References Pacher, P., et al.: Pharmacol. Rev., 58, 87 (2006); Marro, P., et al.: Brain Res., 650, 9 (1994); Abramov, A., et al.: J. Neurosci., 27, 1129 (2007); Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007);<br></p>Formula:C5H4N4O2Colore e forma:Off White SolidPeso molecolare:152.11D-Neopterin
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Precursor in the biosynthesis of Biopterin. First isolated from the pupae of bees.<br>References Kobashi, I., et al.: Agric. Biol. Chem., 35, 47 (1971), Fukushima, S., et al.: J. Biol. Chem., 247, 4549 (1972),<br></p>Formula:C9H11N5O4Colore e forma:NeatPeso molecolare:253.21LY 368962
CAS:Prodotto controllato<p>Applications LY 368962 is a metabolite of the antifolate Pemetrexed (P219500).<br>References Woodland, J.M. et al.: Drug Metab. Dispos., 25, 693 (1997);<br></p>Formula:C19H21N5O7Colore e forma:NeatPeso molecolare:431.40DAMPA-d3
CAS:Prodotto controllato<p>Applications Labelled Methotrexate (M260675) analog. DAMPA is an antitumor agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Martinelli, J.E., et al.: J. Med. Chem., 22, 869 (1979);<br></p>Formula:C152H3H12N7O2Colore e forma:Dark OrangePeso molecolare:328.34Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate
CAS:Purezza:95.0%Colore e forma:Liquid, No data available.Peso molecolare:296.3299865722656N-Methyl Pemetrexed
CAS:Prodotto controllato<p>Impurity Pemetrexed EP Impurity A<br>Applications N-Methyl Pemetrexed (Pemetrexed EP Impurity A) is an impurity of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes.<br>References Kjell, D.P., et al.: Org. Proc. Res. Develop., 9, 738 (2005);<br></p>Formula:C21H23N5O6Colore e forma:NeatPeso molecolare:441.44Theophylline-13C2d6
CAS:Prodotto controllato<p>Applications Labelled Theophylline is a xanthine derivative with diuretic, cardiac stimulant and smooth muscle relaxant activities; isomeric with theobromine. Small amounts occur in tea. Bronchodilator.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cohen, J.L., et al.: Anal. Profiles Drug Subs., 4, 466 (1975), Svedmyr, K., et al.: Allergy, 37, 111 (1982),<br></p>Formula:C513C2H2D6N4O2Colore e forma:NeatPeso molecolare:188.19N,N'-Di-Boc-guanidine
CAS:Purezza:99.0%Colore e forma:Solid, Crystalline Powder or PowderPeso molecolare:259.30599975585945-((tert-Butoxycarbonyl)amino)pyrimidine-2-carboxylic acid
CAS:Purezza:95%Peso molecolare:239.23100280761724-Chloro-2-methylpyrimidine-5-carbonitrile
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:153.570007324218754,6-Dihydroxypyrazolo[3,4-d]pyrimidine-13C,15N2
CAS:Prodotto controllato<p>Applications A labelled metabolite of Allopurinol.<br>References Marro, P., et al.: Brain Res., 650, 9 (1994), Abramov, A., et al.: J. Neurosci., 27, 1129 (2007), Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007),<br></p>Formula:CC4H415N2N2O2Colore e forma:White To BeigePeso molecolare:155.093-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxamide
CAS:Prodotto controllato<p>Impurity Allopurinol EP Impurity C / Allopurinol USP Related Compound C<br>Applications 3-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxamide (Allopurinol EP Impurity C) is an impurity of Allopurinol (A547300).<br></p>Formula:C6H6N6OColore e forma:Off-WhitePeso molecolare:178.15Tenofovir Disoproxil Dimer
CAS:Prodotto controllato<p>Stability Very Hygroscopic and Temperature Sensitive<br>Applications Tenofovir Disoproxil impurity.<br>References Cheng, G., et al.: Chem. Res. Toxicol., 16, 145 (2003),<br></p>Formula:C39H60N10O20P2Colore e forma:White SolidPeso molecolare:1050.905-cyclopropyl-N-(diaminomethylidene)-1-(quinolin-5-yl)-1H-pyrazole-4-carboxamide
CAS:Purezza:98%Peso molecolare:320.3559875488281Ref: 10-F601143
1gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta4-Hydroxy-3-nitrophenylacetic Acid
CAS:Prodotto controllato<p>Applications A metabolite of Nitrotyrosine (N597000), which is excreted in the urine.<br>References van der Vliet, A., et al.: J. Biol. Chem., 272, 7617 (1997), Tabrizi-Fard, M., et al.: Drug Metab. Dispos., 27, 429 (1999), Souza, J., et al.: Arch. Biochem. Biophys., 380, 360 (2000),<br></p>Formula:C8H7NO5Colore e forma:NeatPeso molecolare:197.14Paraxanthine
CAS:<p>Stability Store tightly sealed at RT<br>Applications Paraxanthine is an adenosine receptor ligand and a major metabolite of caffeine.This compound is a contaminant of emerging concern (CECs).<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>Formula:C7H8N4O2Colore e forma:White To Light YellowPeso molecolare:180.16Regadenoson
CAS:Prodotto controllato<p>Applications Regadenoson is a selective and potent A2A adenosine receptor agonist (1). The adenosine A2A receptor is a G-protein-coupled receptor and a key therapeutic target for oncologic, inflammatory, Parkinson's and cardiovascular diseases (2). In rodent studies, it has been shown that co-administration of Regadenoson with Temozolomide (T017775) can increase Temozolomide concentration in the brain (3).<br>References (1) Gao, Z., et al.: J Pharmacol Exp Ther. 298, 209 (2001) (2) Yuan, G., et al.: Expert Opin Drug Discov. 10, 63 (2015) (3) Jackson, S., et al.: J Neurooncol. 126, 433 (2016)<br></p>Formula:C15H18N8O5Colore e forma:Off WhitePeso molecolare:390.35Mono-POC Isopropyl Tenofovir(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tenofovir (T018500) impurity.<br></p>Formula:C17H28N5O7PColore e forma:White SolidPeso molecolare:445.412-(4-Chlorophenyl)amino-4-phenylpyrimidine
CAS:Purezza:95.0%Colore e forma:Solid, No data available.Peso molecolare:281.7399902343755-Azido Oseltamivir
CAS:Prodotto controllato<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Kim, C., et al.: J. Med. Chem., 41, 2451 (1998), Carbain, B., et al.: Chem. Med. Chem., 4, 335 (2009),<br></p>Formula:C16H26N4O4Colore e forma:NeatPeso molecolare:338.406-Methylmercaptopurine-d3
CAS:Prodotto controllato<p>Applications Metabolite of 6-Mercaptopurine, an immunosuppressive drug used to treat leukemia.<br>References Chou, C., et al.: Biochem. Pharmacol., 75, 1601 (2008), Conejo-Garcia, A., et al.: Eur. J. Med. Chem., 43, 1742 (2008), Hawwa, A., et al.: Brit. J. Clin. Pharmacol., 66, 826 (2008), Askanase, A., et al.: J. Rheumatol., 36, 89 (2009),<br></p>Formula:C62H3H3N4SColore e forma:NeatPeso molecolare:169.226-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:277.260009765625Ref: 10-F448203
1gPrezzo su richiesta5g150,00€25gPrezzo su richiesta100gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta1-Methyl-4-(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazine 1-oxide (Imatinib Impurity)
CAS:Purezza:98%Peso molecolare:509.614Ondansetron-d3
CAS:Prodotto controllato<p>Applications Ondansetron-d3 is a labeled specific serotonin (5-HT3) receptor antagonist. Antiemetic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988); Faris, P..L., et al.: Lances, 355, 792 (2000)<br></p>Formula:C18H16D3N3OColore e forma:NeatPeso molecolare:296.38(R)-9-[2-(Hydroxypropyl] Adenine(Desphosphoryl Tenofovir)
CAS:Prodotto controllato<p>Applications (R)-9-[2-(Hydroxypropyl] Adenine (Desphosphoryl Tenofovir) (cas# 14047-28-0) is a useful reagent for preparing the antiviral drug tenofovir.<br>References Dietz, J.-P., et al.: ChemRxiv, 1 (2020)<br></p>Formula:C8H11N5OColore e forma:NeatPeso molecolare:193.212-pyrimidineacetic acid ethyl ester
CAS:Formula:C8H10N2O2Purezza:97%Colore e forma:LiquidPeso molecolare:166.18
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