Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8948 prodotti di "Derivati delle Purine e Pirimidine"
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(S)-Tenofovir Disoproxil Fumarate
CAS:Prodotto controllato<p>Impurity Tenofovir Disoproxil USP Related Compound A<br>Applications The S-enantiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor and used as an anti-HIV agent.Tenofovir Disoproxil USP Related Compound A.<br>References Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formula:C19H30N5O10P·C4H4O4Colore e forma:White SolidPeso molecolare:635.524-Hydroxy-3-nitrophenylacetic Acid
CAS:Prodotto controllato<p>Applications A metabolite of Nitrotyrosine (N597000), which is excreted in the urine.<br>References van der Vliet, A., et al.: J. Biol. Chem., 272, 7617 (1997), Tabrizi-Fard, M., et al.: Drug Metab. Dispos., 27, 429 (1999), Souza, J., et al.: Arch. Biochem. Biophys., 380, 360 (2000),<br></p>Formula:C8H7NO5Colore e forma:NeatPeso molecolare:197.14Ref: 10-F722186
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta500mgPrezzo su richiesta4,6-Dihydroxypyrazolo[3,4-d]pyrimidine-13C,15N2
CAS:Prodotto controllato<p>Applications A labelled metabolite of Allopurinol.<br>References Marro, P., et al.: Brain Res., 650, 9 (1994), Abramov, A., et al.: J. Neurosci., 27, 1129 (2007), Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007),<br></p>Formula:CC4H415N2N2O2Colore e forma:White To BeigePeso molecolare:155.09Zebularine
CAS:Prodotto controllato<p>Applications It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.<br>References Driscoll, J., et al.: J. Med. Chem., 34, 3280 (1991), Ueki, T., et al.: Cancer Res., 60, 1835 (2000),Sherr, C., et al.: Cell, 116, 235 (2004), Dote, H., et al.: Clin. Cancer Res.,11, 4571 ( 2005),<br></p>Formula:C9H12N2O5Colore e forma:NeatPeso molecolare:228.201-Methyluric Acid
CAS:Prodotto controllato<p>Applications A metabolite of Theophylline.<br>References Chen, Y., et al.: Clin. Exper. Pharmacol. Physiol., 36, 828 (2009), Yu, C., et al.: J. Bacteriol., 191, 4624 (2009), Jetter, A., et al.: Eur. J. Clin. Pharmacol., 65, 411 (2009),<br></p>Formula:C6H6N4O3Colore e forma:Light Yellow To Light BrownPeso molecolare:182.141-tert-Butyl 3-ethyl 4-ureido-1H-pyrrole-1,3(2H,5H)-dicarboxylate
CAS:Purezza:95.0%Peso molecolare:299.3269958496094Ref: 10-F826449
1gPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiestaMethotrexate
CAS:<p>Stability Hygroscopic<br>Applications A Folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C20H22N8O5Colore e forma:Yellow To Dark YellowPeso molecolare:454.441-(Naphthalen-2-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea
CAS:Purezza:98%Peso molecolare:297.3580017089844Methotrexate-d3 Diglutamate Trifluoroacetate
CAS:Prodotto controllato<p>Applications Methotrexate-d3 Diglutamate is the isotope labelled analog of Methotrexate Diglutamate (M260720); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C25H26D3N9O8•x(C2HF3O2)•xH2SO4Colore e forma:NeatPeso molecolare:586.58114029812-(5-amino-3-phenyl-1H-pyrazol-1-yl)-6-methylpyrimidin-4(3H)-one
CAS:Purezza:95.0%Peso molecolare:267.29199218754-(3-Butylureido)-2-methylbenzenesulfonylchloride
CAS:Formula:C12H17ClN2O3SPurezza:98%Colore e forma:SolidPeso molecolare:304.792-(Chloromethyl)pyrimidine
CAS:Formula:C5H5ClN2Purezza:95.0%Colore e forma:LiquidPeso molecolare:128.56Methyl 2-(trifluoromethyl)pyrimidine-4-carboxylate
CAS:Purezza:95.0%Peso molecolare:206.12399291992188Tenofovir Monohydrate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tenofovir Monohydrate is an HIV-1 RT inhibitor and antiretroviral drug.<br>References Zhao, Z., et al.: Method for preparing medical salts and/or derivatives of tenofovir disoproxil, and their application for preventing and/or treating HBV and HIV/AIDS infections, CN 101574356 (2009);<br></p>Formula:C9H14N5O4P·H2OColore e forma:NeatPeso molecolare:305.23Paraxanthine-d3
CAS:Prodotto controllato<p>Applications Paraxanthine-d3, is the labeled analogue of Paraxanthine (P192500), an adenosine receptor ligand and a major metabolite of caffeine.<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>Formula:C72H3H5N4O2Colore e forma:NeatPeso molecolare:183.181,3-Dimethyladamantane
CAS:<p>Impurity Memantine Related Compound A (1,3-Dimethyladamantane)<br>Applications 1,3-Dimethyladamantane is a dimethylated adamantane derivative. Memantine impurity A. Memantine Related Compound A (1,3-Dimethyladamantane).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formula:C12H20Colore e forma:NeatPeso molecolare:164.29
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