Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8901 prodotti di "Derivati delle Purine e Pirimidine"
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N4-BENZYL-N2-(4-BROMOPHENYL)-5-FLUOROPYRIMIDINE-2,4-DIAMINE
Purezza:95.0%Peso molecolare:373.229003906251-tert-Butyl 3-ethyl 4-ureido-1H-pyrrole-1,3(2H,5H)-dicarboxylate
CAS:Purezza:95.0%Peso molecolare:299.3269958496094Oxo-Pemetrexed acid
CAS:Prodotto controllatoFormula:C15H14N4O4Colore e forma:NeatPeso molecolare:314.31-((2R,3R,4S,5S)-3,5-DIFLUORO-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)PYRIMIDINE-2,4(1H,3H)-DIONE
Purezza:90.0%Peso molecolare:264.18499755859375Ref: 10-F531024
1gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta6-CHLORO-1-(4-METHOXYBENZYL)-3-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE
CAS:Purezza:95.0%Peso molecolare:280.7099914550781Ref: 10-F506034
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiestaMethotrexate γ-Methyl Ester
CAS:Prodotto controllato<p>Impurity Methotrexate EP Impurity H<br>Applications Methotrexate γ-methyl ester is an impurity of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C21H24N8O5Colore e forma:NeatPeso molecolare:468.47Regadenoson
CAS:Prodotto controllato<p>Applications Regadenoson is a selective and potent A2A adenosine receptor agonist (1). The adenosine A2A receptor is a G-protein-coupled receptor and a key therapeutic target for oncologic, inflammatory, Parkinson's and cardiovascular diseases (2). In rodent studies, it has been shown that co-administration of Regadenoson with Temozolomide (T017775) can increase Temozolomide concentration in the brain (3).<br>References (1) Gao, Z., et al.: J Pharmacol Exp Ther. 298, 209 (2001) (2) Yuan, G., et al.: Expert Opin Drug Discov. 10, 63 (2015) (3) Jackson, S., et al.: J Neurooncol. 126, 433 (2016)<br></p>Formula:C15H18N8O5Colore e forma:Off WhitePeso molecolare:390.358-CYCLOPENTYL-1,3-DIPROPYL-1H-PURINE-2,6(3H,7H)-DIONE
CAS:Purezza:95%Peso molecolare:304.3940124511719(R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine
CAS:Prodotto controllato<p>Applications A acyclic phosphonate nucleotide.<br></p>Formula:C13H22N5O4PColore e forma:White SolidPeso molecolare:343.32Nicotinic Acid-13C6
CAS:<p>Applications Nicotinic Acid-13C6 is labelled Nicotinic acid. It is a precursor of the coenzymes NAD and NADP. Widely distributed in nature; appreciable amounts are found in liver , fish, yeast and cereal grains. Dietary deficiency is associated with pellagra. The term “niacin” has also been applied to nicotinamide or to other derivatives exhibiting the biological activity of nicotinic acid. Vitamin (enzyme cofactor).<br>References Darby, W.J., et al.: Nutr. Rev., 33, 289 (1975), Black, A., et al.: Eur. J. Clin. Nutr., 54, 395 (2000), Cole, T., et al.: Br. Med. J., 320, 1240 (2000), Forshee, R., et al.: J. Nutr., 134, 2733 (2004),<br></p>Formula:C6H5NO2Colore e forma:NeatPeso molecolare:129.07Fenclorim
CAS:Prodotto controllato<p>Applications Herbicide safener.<br>References Lee, H., et al.: Eur. J. Med. Chem., 40, 862 (2005), Wright, S., et al.: Bioorg. Med. Chem. Lett., 17, 5638 (2007), Brazier-Hicks, M., et al.: J. Biol. Chem., 283, 21102 (2008), Vinggaard, A., et al.: Chem. Res. Toxicol., 21, 813 (2008),<br></p>Formula:C10H6Cl2N2Colore e forma:BeigePeso molecolare:225.07Ethyl 2-(2-(dimethylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate
CAS:Purezza:95.0%Peso molecolare:310.35699462890625Zeatin
CAS:<p>Applications Zeatin belongs to the family of plant-growth hormones called cytokinins and it can be used for agricultural use as agrochemicals for increasing crop yields and regulate various aspects of plant growth and development.<br>References Koprna, R., et al.: Bioorgan. Med. Chem., 24, 484-492 (2016)<br></p>Formula:C10H13N5OColore e forma:White To Off-WhitePeso molecolare:219.246-Mercaptopurine-13C2,15N (major)
CAS:Prodotto controllato<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naguib, F., et al.: Biochem. Pharmacol., 50, 1685 (1995), Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004).<br></p>Formula:C313C2H4N315NSColore e forma:NeatPeso molecolare:155.16trans-Zeatin
CAS:Prodotto controllato<p>Applications Zeatin, purified from Zea mays, is a member of the cytokinin group of plant growth factors, the activity of which is attributed to its more stable trans form. Trans-Zeatin inhibits UVB-induced matrix metalloproteinase-1 expression via MAP kinase signaling in human skin fibroblasts. Trans-Zeatin is a potential agent for the management of skin photoaging.<br>References Murashige, T., et al.: Physiol. Plant, 15, 473 (1962), Brenneisen, P., et al.: J. Biol. Chem., 273, 5279 (1998), Choi, M., et al.: J. Dermatol. Sci., 46, 127 (2007), Bae, J., et al.: Food Chem. Toxicol., 46, 1298 (2008),<br></p>Formula:C10H13N5OColore e forma:NeatPeso molecolare:219.248-Descarboxamido-8-cyano Temozolomide
CAS:Prodotto controllato<p>Applications 8-Descarboxamido-8-cyano Temozolomide is a useful synthetic intermediate in the synthesis of Temozolomide (T017775); an imidazotetrazine alkylating agent and antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997); Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999); Hait, W., et al.: Cancer Res., 69, 1263 (2009); Wang, Y., et al.: J. Org. Chem., 62, 7288 (1997)<br></p>Formula:C6H4N6OColore e forma:Light Yellow To Light BrownPeso molecolare:176.14Ref: 10-F605702
1gPrezzo su richiesta5gPrezzo su richiesta10gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta6-Mercaptopurine Monohydrate
CAS:Prodotto controllato<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004),<br></p>Formula:C5H4N4S·H2OColore e forma:YellowPeso molecolare:170.19
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