Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8901 prodotti di "Derivati delle Purine e Pirimidine"
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Methotrexate-d3 Tetraglutamate Trifluoroacetate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Methotrexate-d3 Tetraglutamate is the isotope labelled analog of Methotrexate Tetraglutamate (M260730); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C35H40D3N11O14•(C2HF3O2)xColore e forma:NeatPeso molecolare:844.87-Methyl Xanthine
CAS:Prodotto controllato<p>Applications Metabolite of Theophylline and Caffeine.<br>References Yu, Ch. et al.: J. Bacteriol. 191, 4624 (2009); Geraets, L. et al.: Biochem. Pharmacol. 72, 902 (2006).<br></p>Formula:C6H6N4O2Colore e forma:NeatPeso molecolare:166.14Paraxanthine-1-methyl-d3
CAS:Prodotto controllato<p>Applications An adenosine receptor ligand and a major metabolite of caffeine.<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>Formula:C72H3H5N4O2Colore e forma:YellowPeso molecolare:183.182-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)pyrimidine
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:298.34600830078125Ref: 10-F241812
1gPrezzo su richiesta5g69,00€10g99,00€25g177,00€100g453,00€100mgPrezzo su richiesta250mgPrezzo su richiesta1,7-Dimethyluric Acid-d3
CAS:Prodotto controllatoFormula:C7H5D3N4O3Colore e forma:Off-White To Light GreyPeso molecolare:199.184-(2-Chloropyrimidin-4-yl)morpholine
CAS:Formula:C8H10ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:199.64Tryptamine
CAS:<p>Applications Tryptamine is a monoamine alkaloid found in plants. Tryptamine is commonly used in the preparation of biologically active compounds such as neurotransmitters and psychedelics.<br>References Nichols, D. E., et al.: Curr. Top. Behav. Neurosci., 36, 1(2018); Espinoza, S., et al.: Top. Med. Chem., 23, 175 (2017)<br></p>Formula:C10H12N2Colore e forma:YellowPeso molecolare:160.22L-Phenylalanine-d7
CAS:Prodotto controllato<p>Applications Labelled analogue of L-Phenylalanine, an essential amino acid.<br>References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);<br></p>Formula:C9H4D7NO2Colore e forma:NeatPeso molecolare:172.23Pemetrexed Methyl Ester
CAS:Prodotto controllato<p>Applications Protected Pemetrexed.<br></p>Formula:C22H25N5O6Colore e forma:NeatPeso molecolare:455.4638N-Nitroso Frovatriptan 1
Formula:C14H16N4O2Colore e forma:Off-White To Light YellowPeso molecolare:272.32-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Ethyl Ester
CAS:<p>Applications 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic Acid Ethyl Ester, can be used for the synthesis of Febuxostat (F229000), an antipodagrics.<br>References Zheng, F., et al.: Zhongguo Yiyao Gongye Zazhi, 40, 726 (2009);<br></p>Formula:C14H12N2O3SColore e forma:NeatPeso molecolare:288.32Urea-13C
CAS:<p>Applications Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986); Aebischer, P., et al.: Nat. Med., 2, 696(1996); Prakash, S., et al.: Biotechnol. Bioeng., 46, 621(1995);<br></p>Formula:CH4N2OColore e forma:NeatPeso molecolare:61.056-O-Methyl Guanosine
CAS:Prodotto controllato<p>Applications A guanine derivative that acts as modulators of GTPases and modulator-resistant enzymes; used in drug design and target validation.<br>References Goth-Goldstein, R., et al.: Cancer Res., 40, 2623 (1980), Nakabeppu, Y., et al.: J. Biol. Chem., 259, 13723 (1984), Modrich, P., et al.: Science, 266, 1959 (1994),<br></p>Formula:C11H15N5O5Colore e forma:WhitePeso molecolare:297.27rac Tenofovir-d6
CAS:Prodotto controllato<p>Applications A deuterated acyclic phosphonate nucleotide analogue, reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C92H6H8N5O4PColore e forma:Off White SolidPeso molecolare:293.251,3,5-Trimethyladamantane
CAS:Prodotto controllato<p>Applications An alkyladamantane derivative that are biotransformed via strains of Pseudomonas. It is used to study alkyladamantane adsorption on graphitized thermal carbon black.<br>References Yashkin, S.N. et al.: Rus. Che,. Bull., 57, 2472 (2008); Slepen’kin, A. et al.: Nefeckhim., 33, 406 (1993);<br></p>Formula:C13H22Colore e forma:NeatPeso molecolare:178.315-Methyl-3-methylene-2-hexanone
CAS:Prodotto controllato<p>Applications 5-Methyl-3-methylene-2-hexanone is an impurity of Tetrabenazine (T284000), an antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brossi, A., et al.: Helv. Chim. Acta, 43, 583 (1960);<br></p>Formula:C8H14OColore e forma:NeatPeso molecolare:126.20N-(2-Chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:287.75Ref: 10-F216838
1gPrezzo su richiesta5g105,00€10g194,00€25g347,00€100g893,00€250mgPrezzo su richiesta4-(3-Ethylureido)-2-methylbenzenesulfonyl chloride
CAS:Formula:C10H13ClN2O3SColore e forma:SolidPeso molecolare:276.744-(3,4-dimethylphenyl)-6-(2-fluorophenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:293.34500122070311-(5-ETHYLPYRIMIDIN-2-YL)PIPERIDIN-4-YL METHANESULFONATE
CAS:Purezza:90.0%Peso molecolare:285.3599853515625Ref: 10-F530739
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta
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