Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8892 prodotti di "Derivati delle Purine e Pirimidine"
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2,4-Pteridinediamine-6-methanol
CAS:Prodotto controllatoFormula:C7H8N6OColore e forma:NeatPeso molecolare:192.183-Chlorodiphenylamine
CAS:Prodotto controllato<p>Applications 3-Chlorodiphenylamine (cas# 101-17-7) is a compound useful in organic synthesis.<br></p>Formula:C12H10ClNColore e forma:NeatPeso molecolare:203.677-Hydroxy Memantine Hydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A metabolite of Memantine (M218000), used for the treatment of neurological disorders.<br>References Eiichi, K., et al.: Chem. Pharm. Bull., 33, 4680 (1985),<br></p>Formula:C12H21NO·ClHColore e forma:NeatPeso molecolare:231.76Acetal
CAS:<p>Stability Volatile<br>Applications Acetal is a flavouring component of Baiju and Rum. It is also a useful reactant in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Franitza, Laura, et al.: J. of Agric. and Food Chem., 64(47), 9041-9053 (2016);<br></p>Formula:C6H14O2Colore e forma:ColourlessPeso molecolare:118.177-Hydroxy DAMPA
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A metabolite of DAMPA.<br>References Bleyer, W., et al.: Cancer, 41, 36 ( 1978), Abelson, H., et al.: J. Clin. Oncol., 1, 208 (1983), Fabre, G., et al.: Biochem. Pharmacol., 35, 1325 (1986), Widemann, B., et al.: Clin. Chem., 45, 223 (1999),<br></p>Formula:C15H15N7O3Colore e forma:YellowPeso molecolare:341.324-Dimethylaminobutyraldehyde Diethyl Acetal
CAS:Prodotto controllato<p>Impurity Zolmitriptan USP Related Compound H<br>Applications 4-Dimethylaminobutyraldehyde Diethyl Acetal (Zolmitriptan USP Related Compound H) is used in the preparation of N,N-Dimethyltryptamines, 5-HT1D receptor agonists, for medicinal treatments such as antimigraine drugs.<br>References Chen, C. et al.: J. Org. Chem., 59, 3738 (1994);<br></p>Formula:C11H23NO2Colore e forma:NeatPeso molecolare:189.3Sumatriptan
CAS:Prodotto controllato<p>Applications Sumatriptan is a serotonin 5HT1-receptor agonist.<br>References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988); Doenicke, A., et al.: Lancet 1, 1309 (1988)<br></p>Formula:C14H21N3O2SColore e forma:White To Light YellowPeso molecolare:295.40N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester
CAS:Prodotto controllato<p>Applications N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester prorug of PMPA, phenyl monophosphoramidate, and is a Tenofovir (T018500) derivative, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007), Lee, W. et al.: Antimicrob. Agents Chemother., 49, 1898 (2005);<br></p>Formula:C15H25N6O5PPurezza:>85%Colore e forma:NeatPeso molecolare:400.37N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methylbenzamide
CAS:Peso molecolare:396.4700012207031MTIC-d3
CAS:Prodotto controllato<p>Applications A labelled metabolite of Temozolomide, an antineoplastic.<br></p>Formula:C5H5D3N6OColore e forma:Off White SolidPeso molecolare:171.182-Methylimidazole
CAS:<p>Applications 2-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 2-Methylimidazole as well as other imidazoles can be use as catalyst for refolding of enhanced coloured fluorescent protein. 2-Methylimidazole has been identified as a byproduct of fermentation and is detected in foods and mainstream and side-stream tobacco smoke.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, R. et al.: Arch. Biochem. Biophys., 459, 122 (2007); Chan, P.C. et al.: Arch. Toxicol., 82, 399 (2008); Nishie, K. et al.: Toxicol. Appl. Pharmacol., 14, 301 (1969);<br></p>Formula:C4H6N2Colore e forma:NeatPeso molecolare:82.10Methotrexate Triglutamate Trifluoroacetate
CAS:Prodotto controllato<p>Applications Methotrexate Triglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C30H36N10O11xC2HF3O2Colore e forma:NeatPeso molecolare:712.67Mono-POC Tenofovir
CAS:<p>Stability Hygroscopic<br>Applications An impurity of Tenofovir Disoproxil (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. It is used as an anti-HIV agent and an antiviral.<br>References Gan, L., et al.: Drug Metab. Dispos., 24, 344 (1996), Annaert, P., et al.: Pharm. Res., 14, 492 (1997), Naesens, L., et al.: Antimicrob. Agents Chemother., 42, 1568 (1998), Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formula:C14H22N5O7PColore e forma:White To Light BeigePeso molecolare:403.33Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
CAS:<p>Applications Ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate is an impurity of Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor, used for treatment of hyperuricemia and chronic gout.<br>References Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005);<br></p>Formula:C18H21NO4SColore e forma:NeatPeso molecolare:347.43Nicotinamide-d4 N-Oxide (d4 Major)
CAS:Prodotto controllato<p>Applications A labelled metabolite of Nicotinamide.<br>References Musfeld, C., et al.: J. Pharm. Biomed. Anal., 24, 391 (2001), Sakakibara, Y., et al.: Brain Res., 931, 68 (2002), Zielonka, J., et al.: Chem. Res. Toxicol., 19, 668 (2006), Wieczorkowska, M., et al.: Pharmacol. Rep., 59, 216 (2007),<br></p>Formula:C6H2D4N2O2Colore e forma:NeatPeso molecolare:142.15Memantine Lactose Adduct
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A lactose adduct of Memantine (M218000). Intermediate in the synthesis of reducing carbohydrate Adamantane amines for use in treating Gram positive or Gram negative bacteria infections.<br>References Kustimur, et al.: Chinese Med. J., 116, 633 (2003),<br></p>Formula:C24H41NO10Colore e forma:NeatPeso molecolare:503.58N-Desacetyl 5-Azido Oseltamivir
CAS:Prodotto controllato<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Williams, M., et al.: Bioorg. Med. Chem. Lett., 7, 1837 (1997),<br></p>Formula:C14H24N4O3Colore e forma:NeatPeso molecolare:296.373-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester
CAS:<p>Impurity Allopurinol EP Impurity E / Allopurinol USP Related Compound E<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester (Allopurinol EP Impurity E) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.<br>References Nicolin, A. et al.: Cancer, Chemother. Rep., 57, 3 (1973); Bonmassar, E. et al.: Cancer Res., 35, 1957 (1975)<br></p>Formula:C7H9N3O3Colore e forma:WhitePeso molecolare:183.166-Methyl Nicotinic Acid
CAS:Prodotto controllato<p>Applications A degradation product of Nicotinic acid (N429250). An impurity of Nicotinic acid.<br>References Ensign, J., et al.: Biol. Chem., 239, 2285 (1964), Houghton, C., et al.: Biochem. J., 130, 879 (1972),<br></p>Formula:C7H7NO2Colore e forma:NeatPeso molecolare:137.14N-Desmethyl Zolmitriptan
CAS:<p>Impurity Zolmitriptan USP Related Compound A<br>Stability Hygroscopic<br>Applications A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.<br>References Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 453 (2005),<br></p>Formula:C15H19N3O2Colore e forma:NeatPeso molecolare:273.33
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