Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8897 prodotti di "Derivati delle Purine e Pirimidine"
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1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol
CAS:<p>1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a compound that contains impurities such as fatty acids and uridine. It has been found to be an inhibitor of α-mangostin adduct formation with fatty acids. Additionally, it has been shown to inhibit the activity of GSK-3β, an enzyme involved in various cellular processes. This compound also exhibits inhibitory effects on monascus and safranal, two enzymes involved in the production of certain compounds. Furthermore, it has been found to inhibit calpain, an enzyme responsible for protein degradation. The compound can be used in various research applications involving electrode modification and polylysine immobilization. It may also have potential interactions with other drugs such as cefdinir.</p>Formula:C8H9NO2Purezza:Min. 95%Peso molecolare:151.16 g/molMethotrexate-5-monomethyl ester
CAS:<p>Methotrexate-5-monomethyl ester is an analytical standard that is synthesized synthetically. The synthetic route used to produce the compound has been optimized for high purity, making this product suitable for use as a drug product or impurity standard. The structure of methotrexate-5-monomethyl ester was confirmed by 1H and 13C NMR spectroscopy and mass spectrometry. Methotrexate-5-monomethyl ester is an impurity found in the synthesis of methotrexate and is a metabolite of methotrexate. It has been shown to inhibit DNA synthesis and protein synthesis in animal cells, which may be due to its ability to inhibit transcription factors such as NFATc1, NFkB, STAT3, STAT5A and STAT5B.</p>Formula:C21H24N8O5Purezza:Min. 95%Peso molecolare:468.47 g/molPemetrexed impurity C
CAS:<p>Pemetrexed is a drug product that belongs to the group of drugs called antifolate agents. It is used in the treatment of cancer and is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The impurity C is a natural metabolite that can be found in urine as well as in plasma. This impurity has not been identified as a major metabolite of pemetrexed.</p>Formula:C40H40N10O13Purezza:Min. 95%Peso molecolare:868.81 g/molAllopurinol impurity E
CAS:<p>This product is a synthetic impurity of Allopurinol. It is a cyclization reaction product of dimethylhydrazine and allopurinol in the presence of an organic solvent such as DMF.</p>Formula:C7H9N3O3Purezza:Min. 95%Peso molecolare:183.16 g/mol2,4-Diamino-7-pteridinemethanol
CAS:<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>Formula:C7H8N6OPurezza:Min. 95%Peso molecolare:192.18 g/molZolmitriptan related compound D
CAS:<p>Zolmitriptan related compound D is a drug product that is an analytical impurity of the active ingredient, zolmitriptan. It is a synthetic compound and has been shown to be metabolized in vivo in humans. The chemical name for Zolmitriptan related compound D is 3-acetyl-5-(4-methoxyphenyl)-1H-indole-2,3-dione. This compound has been shown to have niche pharmacological properties that are not shared with other compounds in the same class, such as zolmitriptan.</p>Formula:C19H25N3O4Purezza:Min. 95%Peso molecolare:359.42 g/mol3,4-Dihydro naratriptan
CAS:<p>3,4-Dihydro naratriptan is a medicinal compound that is used as an anti-migraine drug. It is a hydrogenated form of the parent molecule naratriptan and has been shown to have a reaction time of about 30 minutes when catalyzed by palladium. The impurity, 3,4-dihydro naratriptan sulfonamide, has been found to be less potent than the target compound and can be eliminated from the synthesis by using catalytic hydrogenation. 3,4-Dihydro naratriptan sulfonamide can also be reduced by catalytic hydrogenation to yield 3,4-dihydro naratriptan.</p>Formula:C17H23N3O2SPurezza:Min. 95%Peso molecolare:333.45 g/mol4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride
CAS:<p>Please enquire for more information about 4-[1,5-Bis-(2-methylsulfamoylethyl)-1H-indol-3-yl]-1-methylpyridinium chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C20H27N4O4S2•ClPurezza:Min. 95%Peso molecolare:487.04 g/molMeropenem EP Impurity A
<p>Meropenem EP Impurity A is a synthetic, high purity, drug product that is used as an impurity standard for Meropenem. It has been synthesized from a custom synthesis and is available in both natural and synthetic form. This impurity can be used to investigate the metabolism of Meropenem and to determine its stability in different environments. The HPLC analysis of this impurity is available as a pharmacopoeia standard.</p>Formula:C17H27N3O6SPurezza:Min. 95%Peso molecolare:401.48 g/molAllopurinol Sodium
CAS:<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Formula:C5H4N4NaOPurezza:99.93%Colore e forma:SolidPeso molecolare:159.13-(Formylamino)-1H-pyrazole-4-carboxamide
CAS:<p>This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.</p>Formula:C5H6N4O2Purezza:Min. 95%Colore e forma:White To Off-White SolidPeso molecolare:154.13 g/mol5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP
CAS:<p>5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is an impurity found in the synthetic process of iopamidol. It is a nonionic chemical that has been shown to be synthesized using the following methods: dichloride and synthetic. 5-Amino-N,N’-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodo-1,3-benzenedicarboxamide - EP is used as a contrast agent for magnetic resonance imaging (MRI).</p>Formula:C14H18I3N3O6Purezza:Min. 95%Peso molecolare:705.02 g/molMigalastat
CAS:<p>Migalastat (GR181413A free base) is an orally administered, competitive inhibitor of α-galactosidase A (α-Gal A), demonstrating an IC50 value of 0.04 μM against</p>Formula:C6H13NO4Colore e forma:SolidPeso molecolare:163.17Palonosetron
CAS:<p>Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).</p>Formula:C19H24N2OPurezza:98%Colore e forma:SolidPeso molecolare:296.41Ormetoprim
CAS:<p>Ormetoprim (Ro 5-9754), an antibiotic approved for use in the United States, is used to prevent the spread of disease in freshwater aquaculture.</p>Formula:C14H18N4O2Purezza:99.92%Colore e forma:SolidPeso molecolare:274.32Tenofovir exalidex
CAS:<p>Tenofovir exalidex (CMX 157) is a lipid-conjugated acyclic nucleotide analog of Tenofovir, demonstrating efficacy against wild-type and antiretroviral-resistant</p>Formula:C28H52N5O5PPurezza:99.83%Colore e forma:SolidPeso molecolare:569.72Tenofovir diphosphate
CAS:<p>TFV-DP inhibits DNA polymerases, mimics dATP, and is used by HIV-1's reverse transcriptase.</p>Formula:C9H16N5O10P3Colore e forma:SolidPeso molecolare:447.17Neopterin
CAS:<p>D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ.</p>Formula:C9H11N5O4Purezza:99.54%Colore e forma:SolidPeso molecolare:253.21OXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Formula:C18H15N3O3SPurezza:98%Colore e forma:Dark Orange SolidPeso molecolare:353.39Codeine Phosphate CII
CAS:Prodotto controllatoConcentrates of poppy straw; buprenorphine (inn) codeinFormula:C18H21NO3·H3O4PH2OColore e forma:White Crystalline PowderPeso molecolare:406.37 g/mol
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