Derivati delle Purine e Pirimidine
Le purine hanno una struttura biciclica, composta da un anello a sei membri fuso con un anello a cinque membri, entrambi contenenti atomi di azoto in posizioni chiave. I derivati delle purine, come l’adenina e la guanina, sono essenziali per la formazione del DNA e dell’RNA. Questi composti trovano applicazione terapeutica nei trattamenti contro il cancro e le malattie virali, inibendo la replicazione cellulare. Le pirimidine, invece, hanno una struttura monociclica a sei membri con due atomi di azoto. I loro derivati, come la citosina, la timina e l’uracile, sono anch’essi componenti fondamentali del DNA e dell’RNA e vengono utilizzati in chemioterapia e nei trattamenti antivirali.
Presso CymitQuimica, offriamo derivati delle purine e pirimidine per la ricerca in biologia molecolare, genomica e sviluppo di terapie innovative.
Trovati 8902 prodotti di "Derivati delle Purine e Pirimidine"
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3,5,3',5'-Tetraiodo Thyrolactic Acid (~90%)
CAS:Prodotto controllato<p>Stability Hygroscopic, Temperature sensitive<br>Applications 3,5,3',5'-Tetraiodo Thyrolactic Acid is a thyroid hormone analogue. A Thyroxine (T425600) analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989); Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992); Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999); Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002);<br></p>Formula:C15H10I4O5Purezza:~90%Colore e forma:BeigePeso molecolare:777.851-(4-tert-Butylphenyl)-2-pyrimidin-4-yl ethanol
CAS:Formula:C16H20N2OPurezza:≥95%Colore e forma:SolidPeso molecolare:256.349Methyl Acetoacetate
CAS:Prodotto controllato<p>Applications 3-Oxobutanoic Acid Methyl Ester is a chemical reagent used in the synthesis of pharmaceuticals. It participates in the Biginelli reaction, forming molecules including dihydropyrimidinones.<br>References Ranu, B. et al.: J. Org. Chem. 65, 6270 (2000); Lu, J. et al.: Tetrahedron Lett., 41, 9075 (2000); Lu, J. et al.: Synlett., 1, 63 (2000);<br></p>Formula:C5H8O3Colore e forma:NeatPeso molecolare:116.124-(3-fluorophenyl)-6-(furan-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:255.2519989013672(6-Methoxy-2-methylsulfanyl-pyrimidin-4-yl)-piperidin-4-yl-amine hydrochloride
CAS:Purezza:95.0%Peso molecolare:290.80999755859375Memantine-Glucose Adduct
Prodotto controllatoFormula:C18H31NO5Colore e forma:NeatPeso molecolare:341.442Urea-13C
CAS:<p>Applications Labelled Urea. Physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diuretic.<br>References Demetriou, A., et al.: Science, 233, 1190 (1986); Aebischer, P., et al.: Nat. Med., 2, 696(1996); Prakash, S., et al.: Biotechnol. Bioeng., 46, 621(1995);<br></p>Formula:CH4N2OColore e forma:NeatPeso molecolare:61.052-[5-amino-3-(2-thienyl)-1H-pyrazol-1-yl]-6-methylpyrimidin-4(3H)-one
CAS:Purezza:95.0%Peso molecolare:273.309997558593754-(4-bromophenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:354.25100708007813-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester
CAS:<p>Impurity Allopurinol EP Impurity E / Allopurinol USP Related Compound E<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester (Allopurinol EP Impurity E) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.<br>References Nicolin, A. et al.: Cancer, Chemother. Rep., 57, 3 (1973); Bonmassar, E. et al.: Cancer Res., 35, 1957 (1975)<br></p>Formula:C7H9N3O3Colore e forma:WhitePeso molecolare:183.16N-Desmethyl Zolmitriptan
CAS:<p>Impurity Zolmitriptan USP Related Compound A<br>Stability Hygroscopic<br>Applications A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.<br>References Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 453 (2005),<br></p>Formula:C15H19N3O2Colore e forma:NeatPeso molecolare:273.33Nicotinic Acid-13C1 (~1% unlabeled)
CAS:<p>Applications Isotope labelled analogue of Nicotinic Acid (N429250), also known as vitamin B3, is an essential nutrient that must be obtained from a dietary source in order for normal body function. The administration of Nicotinic Acid in animal models of ischemia was shown to significantly reduce the size of infarction and improve functional recovery. Current findings suggest that nicotinic acid may have therapeutic potential for the treatment of traumatic brain injury.<br>References Xu, P., et al.: Mech Age. Dev., 4, 287 (2010); Hoane, M.R., et al.: J. Neurotrauma, 20, 1189 (2003);<br></p>Formula:C513CH5NO2Colore e forma:NeatPeso molecolare:124.12-[4-(3-chlorophenyl)piperazin-1-yl]-6-methyl-3,4-dihydropyrimidin-4-one
CAS:Purezza:98%Peso molecolare:304.7799987792969Tert-butyl 4-(5-hydroxypyrimidin-2-yl)piperazine-1-carboxylate
CAS:Purezza:98%Peso molecolare:280.3280029296875Ref: 10-F768179
1gPrezzo su richiesta2gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta500mgPrezzo su richiesta4-(Chloromethyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
CAS:Purezza:95+%Peso molecolare:429.9100036621094Ref: 10-F635743
1gPrezzo su richiesta5gPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta1,3,5-Trimethyladamantane
CAS:Prodotto controllato<p>Applications An alkyladamantane derivative that are biotransformed via strains of Pseudomonas. It is used to study alkyladamantane adsorption on graphitized thermal carbon black.<br>References Yashkin, S.N. et al.: Rus. Che,. Bull., 57, 2472 (2008); Slepen’kin, A. et al.: Nefeckhim., 33, 406 (1993);<br></p>Formula:C13H22Colore e forma:NeatPeso molecolare:178.31Formaldehyde 2,4-Dinitrophenylhydrazone
CAS:<p>Stability Shock Sensitive<br>Applications Formaldehyde 2,4-Dinitrophenylhydrazone is a dinitrophenylhydrazone (DNPH) derivative of an aliphatic aldehyde found in mainstream cigarette smoke.<br>References Delgado, B. et al.: J. Liq. Chrom. Rel. Technol., 31, 361 (2008); Miller, J.H. et al.: J. Chrom. Sci., 48, 12 (2010);<br></p>Formula:C7H6N4O4Colore e forma:NeatPeso molecolare:210.15CAL-101
CAS:Prodotto controllato<p>Applications CAL-101 is a PI3K/mTOR pathway inhibitor used in the treatment of myeloid leukemia through sensitizing the cells to combatting drugs. Potent PI3K-p110-delta inhibitor.<br>References Airiau, K. et al.: Cell. Death. Dis., 4, e827 (2013); Kulesz-Martin, M. et al Canc. Biol. Ther., 14m 95 (2013);<br></p>Formula:C22H18FN7OColore e forma:Light BrownPeso molecolare:415.40Ref: 10-F053934
1gPrezzo su richiesta5gPrezzo su richiesta10gPrezzo su richiesta25gPrezzo su richiesta4-(2H-1,3-benzodioxol-5-yl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:297.3299865722656Ethyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
CAS:Purezza:95.0%Colore e forma:Liquid, No data available.Peso molecolare:334.3789978027344Ref: 10-F242138
5gPrezzo su richiesta10gPrezzo su richiesta25gPrezzo su richiesta100gPrezzo su richiestaIsonicotinic Acid
CAS:<p>Applications Used in the biological study of differentiation induced by nicotinic acid, nicotinamide and isonicotinic acid in human leukemia cell lines.<br>References Zeilinger, S., et al.: J. Biol. Chem., 271, 25624 (1996), Panagiotou, G., et al.: J. Biotechnol., 118, 304 (2005),<br></p>Formula:C6H5NO2Colore e forma:Light BrownPeso molecolare:123.11Tri-POC Tenofovir Dimer (>90%)
CAS:Prodotto controllato<p>Stability Very Hygroscopic<br>Applications Tri-POC Tenofovir Dimer is a dimer of Tenofovir Disoproxil (T018505), an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. It is also used in the preparation of phosphocitrate for the treatment of rheumatoid and osteoarthritis in the elderly.<br>References Turhanen, P. et al.: J. Org. Chem., 72, 1468 (2007);<br></p>Formula:C34H52N10O17P2Purezza:>90%Colore e forma:White To Light BeigePeso molecolare:934.784-Amino-1,3-dimethyl-5-nitrosouracil x-H2O
CAS:Prodotto controllato<p>Applications 4-Amino-1,3-dimethyl-5-nitrosouracil is a useful building block for organic synthesis.<br></p>Formula:C6H8N4O3Colore e forma:NeatPeso molecolare:184.153,4-Dihydro Naratriptan Oxalate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 3,4-Dihydro Naratriptan Oxalate is the basic form of 3,4-Dihydro Naratriptan(D449205); it is an impurity of Naratriptan (N378730), It is a triptan drug and is used for the treatment of migraine headaches.<br>References Dulery, B.D., et al.: J. Pharm. Biomed. Anal., 15, 1009 (1997), Havanka, H., et al.: Clin. Ther., 22, 970 (2000),<br></p>Formula:C17H23N3O2S·C2H2O4Colore e forma:White To Light YellowPeso molecolare:333.45 + 90.03Tenofovir Alafenamide Fumarate
CAS:Prodotto controllato<p>Applications Tenofovir Alafenamide Fumarate is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007),<br></p>Formula:C21H29N6O5P·C4H4O4Colore e forma:NeatPeso molecolare:592.5381Methotrexate-Cadaverine-Biotin Conjugate
Prodotto controllato<p>Applications Methotrexate-Cadaverine-Biotin Conjugate is biotin labelled Methotrexate. Methotrexate (M260675) is a folic acid antagonist and it is used as a antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C35H48N12O6SPurezza:>85%Colore e forma:NeatPeso molecolare:764.94-(3,4-dimethylphenyl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:365.4330139160156N-((4,6-dimethoxypyrimidin-2-yl)carbamoyl)-3-(trifluoromethyl)pyridine-2-sulfonamide
CAS:Purezza:98%Colore e forma:SolidPeso molecolare:407.3200073N-Nitroso Desmethyl Sumatriptan
Prodotto controllatoFormula:C13H18N4O3SColore e forma:Orange To BrownPeso molecolare:310.372(3R,11bR)-Tetrabenazine
CAS:Prodotto controllatoFormula:C19H27NO3Colore e forma:NeatPeso molecolare:317.42Guanidinoacetic Acid
CAS:<p>Applications Guanidinoacetic Acid is an important marker for renal failure, in kidney transplantation, and for the renal metabolic activity.<br>References Zugno, A., et al.: Neurochem. Res., 33, 1804 (2008), Debray, F., et al.: Neurol., 71, 44 (2008), da Silva, R., et al.: Am. J. Physiol., 296, E256 (2009),<br></p>Formula:C3H7N3O2Colore e forma:WhitePeso molecolare:117.114-[6-(2-Methoxy-phenyl)-pyridin-3-yl]-pyrimidin-2-ylamine
Purezza:95.0%Peso molecolare:278.315002441406255-Cyclopropyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one
CAS:Formula:C7H8N2OSPurezza:95.0%Colore e forma:SolidPeso molecolare:168.211-(6-Ethoxy-2-methylsulfanyl-pyrimidin-4-yl)-piperidin-3-ylamine hydrochloride
CAS:Purezza:95.0%Peso molecolare:304.8399963378906L-Phenyl-d5-alanine-2,3,3-d3
CAS:Prodotto controllato<p>Applications L-Phenyl-d5-alanine-2,3,3-d3 is an isotope labelled compound of L-Phenylalanine (P319415). L-Phenylalanine (Aspartame EP Impurity C) is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further converted into dopamine, norepinephrine, and epinephrine. L-Phenylalanine is produced for medical, feed, and nutritional applications such as in the preparation of Aspartame. Neuroprotective product.<br>References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977)<br></p>Formula:C9D8H3NO2Colore e forma:NeatPeso molecolare:173.24L-Aspartyl-L-phenylalanine Hydrochloride
CAS:Prodotto controllato<p>Applications L-Aspartyl-L-phenylalanine is an impurity of Thiamine (T344185). Thiamine Impurity B.<br>References Aluwihare, L., et al.: Science, 308, 1007 (2005), Koch, B., et al.: Anal. Chem., 79, 1758 (2007), Reemtsma, T., et al.: Environ. Sci. Technol., 42, 1430 (2008),<br></p>Formula:C13H16N2O5xHClColore e forma:NeatPeso molecolare:280.284-(2H-1,3-benzodioxol-5-yl)-6-(furan-2-yl)pyrimidin-2-amine
CAS:Purezza:95.0%Peso molecolare:281.270996093752-[3-Carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid
CAS:Prodotto controllato<p>Applications 2-[3-Carboxy-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid is an impurity of Febuxostat (F229000), an xanthine oxidase/ xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout.<br>References Kadivar, M.H.,e t al.: J. Pharm. Biomed. Anal., 56, 749 (2011);<br></p>Formula:C16H17NO5SColore e forma:White SolidPeso molecolare:335.37Sodium ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogenphosphate
CAS:Purezza:98.0%Peso molecolare:346.164001464843751-phenyl-5-[(pyrimidin-2-ylsulfanyl)methyl]-1H-1,2,3-triazole-4-carboxylic acid
CAS:Purezza:95.0%Peso molecolare:313.3399963378906
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