Derivati delle Benzodiazepine
Le benzodiazepine sono composti organici con un nucleo biciclico fuso di benzodiazepina, ampiamente utilizzati nello sviluppo di farmaci con proprietà ansiolitiche, sedative, anticonvulsivanti e miorilassanti. I loro derivati includono strutture modificate che ne migliorano la selettività e il profilo farmacocinetico, consentendo la creazione di nuove molecole con applicazioni terapeutiche avanzate. Questi composti sono impiegati nella formulazione di API per il trattamento dei disturbi del sonno, dell’ansia, dell’epilessia e degli spasmi muscolari. Inoltre, i derivati delle benzodiazepine sono fondamentali nella ricerca di nuovi agenti psicotropi e nell’ottimizzazione dei trattamenti neurologici.
Presso CymitQuimica, offriamo derivati delle benzodiazepine di alta purezza per applicazioni in sintesi chimica, sviluppo farmaceutico e neuroscienze.
Trovati 333 prodotti di "Derivati delle Benzodiazepine"
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Clonazepam
CAS:Prodotto controllato<p>Applications Antiepileptic agent with anxiolytic and antimanic properties. Anticonvulsant.This is a controlled substance (depressant).<br>References Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Formula:C15H10ClN3O3Colore e forma:WhitePeso molecolare:315.71Clobazam-13C6
CAS:Prodotto controllato<p>Applications Clobazam-13C6 is the isotope labelled analog of Clobazam (C582500); a benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic and anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979); Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C6C10H13ClN2O2Colore e forma:Off-WhitePeso molecolare:306.707-Acetamido Clonazepam
CAS:Prodotto controllato<p>Applications Clonazepam (C587080) metabolite.<br>References Huang, W., et al.: J. Anal. Toxicol., 19, 333 (1995), Rittner, M., et al.: J. Anal. Toxicol., 25, 115 (2001),<br></p>Formula:C17H14ClN3O2Colore e forma:NeatPeso molecolare:327.76Deschloro Clobazam
CAS:Prodotto controllato<p>Applications Deschloro Clobazam is a metabolite of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant.<br>References Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C16H14N2O2Colore e forma:Off WhitePeso molecolare:266.29Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate
CAS:Prodotto controllato<p>Impurity Flumazenil EP Impurity E<br>Applications Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate (Flumazenil EP Impurity E) is used in the biological studies and preparation of imidazobenzodiazepines as probes for diazepaminsensitive receptor pharmacophore.<br>References Zhang, P., et al.: J. Med. Chem., 38, 1679 (1995)<br></p>Formula:C15H15N3O3Colore e forma:NeatPeso molecolare:285.302-Bromo-acetamide-2’,5-dichlorobenzophenone
CAS:Prodotto controllato<p>Stability Unstable in Solution, Moisture Sensitive<br>Applications Used in the synthesis of Cloxazolam and its metabolites.<br>References Ji, M. et al.: Zhongguo Yaoke Daxue Xuebao 24, 180 (1993); Ji, M. et al.: Zhongguo Yaoke Daxue Xuebao 25, 69 (1994).<br></p>Formula:C15H10BrCl2NO2Colore e forma:NeatPeso molecolare:387.061-Hydroxy Alprazolam
CAS:Prodotto controllatoFormula:C17H13ClN4OColore e forma:NeatPeso molecolare:324.767-Amino Nitrazepam
CAS:Prodotto controllato<p>Applications A metabolite of Nitrazepam (N490140).<br>References Randall, L.O., et al.: Biochem. Pharmacol., 8, 15 (1961),<br></p>Formula:C15H13N3OColore e forma:Light YellowPeso molecolare:251.286-Methyl Bromazepam
CAS:Prodotto controllatoFormula:C15H12BrN3OColore e forma:NeatPeso molecolare:330.185-Nitro-2-(bromoacetamido)benzophenone
CAS:<p>Applications Nitrazepam derivative.<br>References Hagishita, S., et al.: Bioorg. Med. Chem., 5, 1433 (1997), Amblard, M., et al.: J. Med. Chem., 42, 4185 (1999), Schafferhans, A., et al.: J. Mol. Biol., 307, 407 (2001).<br></p>Formula:C15H11BrN2O4Colore e forma:NeatPeso molecolare:363.163-Hydroxy Bromazepam
CAS:Prodotto controllato<p>Applications Major metabolite of Bromazepam (B678500)<br>References Musshoff, F., et al.: Clin. Chem. Lab. Med., 36, 803 (1998), El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001), Darzy, K., et al.: Clin. Endocrinol., 70, 287 (2009),<br></p>Formula:C14H10BrN3O2Colore e forma:Off-WhitePeso molecolare:332.157-Chloro-1-methyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-4-amine
CAS:<p>Applications An impurity of Alprazolam (A575650). The major degradation product in Alprazolam tablets during their stability assay.<br>References Nudelman, N., et al.: J. Pharm. Sci., 91, 1274 (2002), Marin, A., et al.: Anal. Chem., 77, 471 (2005),<br></p>Formula:C17H13ClN4Colore e forma:White To Off-WhitePeso molecolare:308.76Brotizolam
CAS:Prodotto controllato<p>Applications A hypnotic and a sedative, also used in veterinary medicine as an appetite stimulant<br>References Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Nishino, T., et al.: J. Pharmacol. Sci., 107, 349 (2008), Yamashiro, T., et al.: J. Clin. Pharm, Ther., 33, 273 (2008), Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008),<br></p>Formula:C15H10BrClN4SColore e forma:WhitePeso molecolare:393.69Nitrazepam
CAS:Prodotto controllato<p>Applications Anticonvulsant; hypnotic.Controlled substance (depressant).<br>References Rieder, et al.: Arzneim.-Forsch., 23, 212 (1973), Kangas, L., Acta Pharmacol. Toxicol., 45, 16 (1979), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 9, 487 (1980).<br></p>Formula:C15H11N3O3Colore e forma:White To Off-WhitePeso molecolare:281.273-Hydroxy Bromazepam 1.0 mg/mL in Methanol
CAS:Prodotto controllatoFormula:C14H10BrN3O2Colore e forma:ColourlessPeso molecolare:332.157-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
CAS:Prodotto controllatoFormula:C10H9FN2O2Colore e forma:NeatPeso molecolare:208.191-Methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Purezza:98%Peso molecolare:250.30099487304688(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate
CAS:Purezza:97.0%Peso molecolare:402.24798583984375
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