Derivati delle Benzodiazepine
Le benzodiazepine sono composti organici con un nucleo biciclico fuso di benzodiazepina, ampiamente utilizzati nello sviluppo di farmaci con proprietà ansiolitiche, sedative, anticonvulsivanti e miorilassanti. I loro derivati includono strutture modificate che ne migliorano la selettività e il profilo farmacocinetico, consentendo la creazione di nuove molecole con applicazioni terapeutiche avanzate. Questi composti sono impiegati nella formulazione di API per il trattamento dei disturbi del sonno, dell’ansia, dell’epilessia e degli spasmi muscolari. Inoltre, i derivati delle benzodiazepine sono fondamentali nella ricerca di nuovi agenti psicotropi e nell’ottimizzazione dei trattamenti neurologici.
Presso CymitQuimica, offriamo derivati delle benzodiazepine di alta purezza per applicazioni in sintesi chimica, sviluppo farmaceutico e neuroscienze.
Trovati 333 prodotti di "Derivati delle Benzodiazepine"
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5-Chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)benzophenone
CAS:<p>Applications An impurity of Alprazolam (A575650).<br>References Cho, M., et al.: J. Med. Chem., 29, 1346 (1986), Hall, M., et al.: J. Anal. Toxicol., 19, 511 (1995), Nudelman, N., et al.: J. Pharm. Sci., 84, 998 (1995), Yuan, R., et al.: J. Clin. Pharmacol., 39, 1109 (1999),<br></p>Formula:C16H12ClN3OColore e forma:NeatPeso molecolare:297.74Clonazepam-13C2 ,15N
CAS:Prodotto controllato<p>Applications Clonazepam-13C2 ,15N, is the labeled analogue of Clonazepam (C587080), an antiepileptic agent with anxiolytic and antimanic properties.<br>References Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Formula:C1313C2H10ClN215NO3Colore e forma:NeatPeso molecolare:318.69Nor-Flunitrazepam
CAS:Prodotto controllato<p>Applications A metabolite of Flunitrazepam (F500700).<br>References Asai, H., et al.: J. Pharmacol. Exp. Ther., 277, 1004 (1996), Kilicarslan, T., et al.: Drug Metab. Dispos., 29, 460 (2001), Tanaka, E., et al.: J. Toxicol. Clin. Toxicol., 40, 69 (2002),<br></p>Formula:C15H10FN3O3Colore e forma:YellowPeso molecolare:299.262-Amino-5-chlorobenzophenone
CAS:Prodotto controllato<p>Applications A metabolite of Diazepam; but has a much weaker anticonvulsant effect.<br>References Hara, T., et al.: J. Med. Chem., 21, 263 (1978),<br></p>Formula:C13H10ClNOColore e forma:YellowPeso molecolare:231.68N-Desmethyl Clobazam-13C6
CAS:Prodotto controllato<p>Applications N-Desmethyl Clobazam-13C6 is an isotope labelled metabolite of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types.<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979); Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C913C6H11ClN2O2Colore e forma:Off-WhitePeso molecolare:292.6695-Chloro-2-(3-chloromethyl-4H-1,2,4-triazol-4-yl)-benzophenone
CAS:Prodotto controllato<p>Applications 5-Chloro-2-(3-chloromethyl-4H-1,2,4-triazol-4-yl)-benzophenone is an impurity in the synthesis of Estazolam (E668380), a benzodiazepine derivative possessing anxiolytic, anticonvulsant, and muscle relaxant properties. It is commonly prescribed to treat short-term insomnia.<br>References Barroso, M., et al.: Anal. Bioanal. Chem., 396, 3059 (2010), Rodgers, A., et al.: Chem. Res., Toxicol., 23, 724 (2010), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),<br></p>Formula:C16H11Cl2N3OColore e forma:NeatPeso molecolare:332.187-Acetamido Nitrazepam
CAS:Prodotto controllatoFormula:C17H15N3O2Colore e forma:NeatPeso molecolare:293.323-Amino-6-chloro-4-phenylcarbostyril
CAS:<p>Applications Intermediate in the preparation of Alprazolam impurities.<br>References Hanawa, T., et al.: Drug Dev. Ind. Pharm., 26, 1199 (2000), Cheng, P., et al.: Bioorg. Med. Chem. Lett., 18, 3787 (2008),<br></p>Formula:C15H11ClN2OColore e forma:NeatPeso molecolare:270.712-Bromo-N-[2-(2-chlorobenzoyl)-4-nitrophenyl]acetamide(Clonazepam Impurity)
CAS:Prodotto controllato<p>Applications An impurity from the synthesis of clonazepam (C587080)<br></p>Formula:C15H10BrClN2O4Colore e forma:Light YellowPeso molecolare:397.612-[3-(Hydroxymethyl)-5-methyl-4-triazolyl]-5-chlorobenzophenone
CAS:<p>Applications An impurity of Alprazolam (A575650).<br>References Nudelman, N., et al.: J. Pharm. Sci., 91, 1274 (2002), Marin, A., et al.: Anal. Chem., 77, 471 (2005),<br></p>Formula:C17H14ClN3O2Colore e forma:Off White SolidPeso molecolare:327.763-Hydroxy Bromazepam-d4
CAS:Prodotto controllato<p>Applications Major metabolite of labelled Bromazepam (B678502)<br>References Musshoff, F., et al.: Clin. Chem. Lab. Med., 36, 803 (1998), El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001), Darzy, K., et al.: Clin. Endocrinol., 70, 287 (2009),<br></p>Formula:C14H6D4BrN3O2Colore e forma:Light YellowPeso molecolare:336.18Clonazepam-d4
CAS:Prodotto controllato<p>Applications Labelled Clonazepam (C587080). Antiepileptic agent with anxiolytic and antimanic properties. Anticonvulsant.This is a controlled substance (depressant).<br>References Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Formula:C152H4H6ClN3O3Colore e forma:Yellow To Dark YellowPeso molecolare:319.74N-Desmethyl Clobazam-d5
CAS:Prodotto controllato<p>Applications The major labelled metabolite of Clobazam (C582500). Controlled substance (depressant).<br>References Bardy, A., et al.: Brain Develop., 13, 174 (1991), Patsalos, P., et al.: Epilepsia, 43, 365 (2002), Venisse, N., et al.: J. Anal. Toxicol., 27, 7 (2003),<br></p>Formula:C152H5H6ClN2O2Colore e forma:Off-WhitePeso molecolare:291.74Flumazenil
CAS:Prodotto controllato<p>Applications Flumazenil is an imidazodiazepine which selectively blocks the central effects of classic benzodiazepines. It is used as benzodiazepine antagonist.<br>References Hunkeler, W., et al.: Nature, 290, 514 (1981), Pole, P., et al.: Arch. Pharmacol., 316, 317 (1981), Timm, U., et al.: Arzneim.-Forsch., 33, 358 (1983),<br></p>Formula:C15H14FN3O3Colore e forma:Off WhitePeso molecolare:303.293-Amino-6-nitro-4-phenyl-2(H)-quinolinone
CAS:Prodotto controllatoFormula:C15H11N3O3Colore e forma:OrangePeso molecolare:281.272-(2-Amino-5-bromobenzoyl)pyridine
CAS:<p>Impurity Bromazepam EP impurity A<br>Applications Intermediate in the preparation of Bromazepam.<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998), El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001), Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005),<br></p>Formula:C12H9BrN2OColore e forma:Light Yellow To YellowPeso molecolare:277.12Alprazolam-d3
CAS:Prodotto controllato<p>Applications Controlled substance (depressant). Anxiolytic.<br>References Sethy, V.H., et al.: Arch. Pharmacol., 301, 157 (1978), Fawcett, J.A., et al.: Pharmacotherapy, 2, 242 (1982),<br></p>Formula:C17H10ClD3N4Colore e forma:NeatPeso molecolare:311.80Clobazam-d5
CAS:Prodotto controllato<p>Applications Labelled Clobazam (C582500). Benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993),<br></p>Formula:C16H8D5ClN2O2Colore e forma:Off White PowderPeso molecolare:305.772-Chloro-N-[2-(2-chlorobenzoyl)-4-nitrophenyl]acetamide
CAS:Formula:C15H10Cl2N2O4Colore e forma:NeatPeso molecolare:353.166-Chloro-2,3-dimethyl-1-phenyl-1H-benzo[d]imidazol-3-ium Chloride
CAS:<p>Applications 6-Chloro-2,3-dimethyl-1-phenyl-1H-benzo[d]imidazol-3-ium Chloride is a degradation product of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant.<br>References Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C15H14ClN2·ClColore e forma:NeatPeso molecolare:293.191Clonazepam
CAS:Prodotto controllato<p>Applications Antiepileptic agent with anxiolytic and antimanic properties. Anticonvulsant.This is a controlled substance (depressant).<br>References Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Formula:C15H10ClN3O3Colore e forma:WhitePeso molecolare:315.71Clobazam-13C6
CAS:Prodotto controllato<p>Applications Clobazam-13C6 is the isotope labelled analog of Clobazam (C582500); a benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic and anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979); Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C6C10H13ClN2O2Colore e forma:Off-WhitePeso molecolare:306.707-Acetamido Clonazepam
CAS:Prodotto controllato<p>Applications Clonazepam (C587080) metabolite.<br>References Huang, W., et al.: J. Anal. Toxicol., 19, 333 (1995), Rittner, M., et al.: J. Anal. Toxicol., 25, 115 (2001),<br></p>Formula:C17H14ClN3O2Colore e forma:NeatPeso molecolare:327.76Deschloro Clobazam
CAS:Prodotto controllato<p>Applications Deschloro Clobazam is a metabolite of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant.<br>References Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C16H14N2O2Colore e forma:Off WhitePeso molecolare:266.29Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate
CAS:Prodotto controllato<p>Impurity Flumazenil EP Impurity E<br>Applications Ethyl 5-Methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate (Flumazenil EP Impurity E) is used in the biological studies and preparation of imidazobenzodiazepines as probes for diazepaminsensitive receptor pharmacophore.<br>References Zhang, P., et al.: J. Med. Chem., 38, 1679 (1995)<br></p>Formula:C15H15N3O3Colore e forma:NeatPeso molecolare:285.302-Bromo-acetamide-2’,5-dichlorobenzophenone
CAS:Prodotto controllato<p>Stability Unstable in Solution, Moisture Sensitive<br>Applications Used in the synthesis of Cloxazolam and its metabolites.<br>References Ji, M. et al.: Zhongguo Yaoke Daxue Xuebao 24, 180 (1993); Ji, M. et al.: Zhongguo Yaoke Daxue Xuebao 25, 69 (1994).<br></p>Formula:C15H10BrCl2NO2Colore e forma:NeatPeso molecolare:387.061-Hydroxy Alprazolam
CAS:Prodotto controllatoFormula:C17H13ClN4OColore e forma:NeatPeso molecolare:324.767-Amino Nitrazepam
CAS:Prodotto controllato<p>Applications A metabolite of Nitrazepam (N490140).<br>References Randall, L.O., et al.: Biochem. Pharmacol., 8, 15 (1961),<br></p>Formula:C15H13N3OColore e forma:Light YellowPeso molecolare:251.286-Methyl Bromazepam
CAS:Prodotto controllatoFormula:C15H12BrN3OColore e forma:NeatPeso molecolare:330.185-Nitro-2-(bromoacetamido)benzophenone
CAS:<p>Applications Nitrazepam derivative.<br>References Hagishita, S., et al.: Bioorg. Med. Chem., 5, 1433 (1997), Amblard, M., et al.: J. Med. Chem., 42, 4185 (1999), Schafferhans, A., et al.: J. Mol. Biol., 307, 407 (2001).<br></p>Formula:C15H11BrN2O4Colore e forma:NeatPeso molecolare:363.163-Hydroxy Bromazepam
CAS:Prodotto controllato<p>Applications Major metabolite of Bromazepam (B678500)<br>References Musshoff, F., et al.: Clin. Chem. Lab. Med., 36, 803 (1998), El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001), Darzy, K., et al.: Clin. Endocrinol., 70, 287 (2009),<br></p>Formula:C14H10BrN3O2Colore e forma:Off-WhitePeso molecolare:332.157-Chloro-1-methyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinolin-4-amine
CAS:<p>Applications An impurity of Alprazolam (A575650). The major degradation product in Alprazolam tablets during their stability assay.<br>References Nudelman, N., et al.: J. Pharm. Sci., 91, 1274 (2002), Marin, A., et al.: Anal. Chem., 77, 471 (2005),<br></p>Formula:C17H13ClN4Colore e forma:White To Off-WhitePeso molecolare:308.76Brotizolam
CAS:Prodotto controllato<p>Applications A hypnotic and a sedative, also used in veterinary medicine as an appetite stimulant<br>References Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Nishino, T., et al.: J. Pharmacol. Sci., 107, 349 (2008), Yamashiro, T., et al.: J. Clin. Pharm, Ther., 33, 273 (2008), Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008),<br></p>Formula:C15H10BrClN4SColore e forma:WhitePeso molecolare:393.69Nitrazepam
CAS:Prodotto controllato<p>Applications Anticonvulsant; hypnotic.Controlled substance (depressant).<br>References Rieder, et al.: Arzneim.-Forsch., 23, 212 (1973), Kangas, L., Acta Pharmacol. Toxicol., 45, 16 (1979), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 9, 487 (1980).<br></p>Formula:C15H11N3O3Colore e forma:White To Off-WhitePeso molecolare:281.273-Hydroxy Bromazepam 1.0 mg/mL in Methanol
CAS:Prodotto controllatoFormula:C14H10BrN3O2Colore e forma:ColourlessPeso molecolare:332.157-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
CAS:Prodotto controllatoFormula:C10H9FN2O2Colore e forma:NeatPeso molecolare:208.191-Methyl-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Purezza:98%Peso molecolare:250.30099487304688(S)-Methyl 3-(7-bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanoate
CAS:Purezza:97.0%Peso molecolare:402.247985839843753-AMINO-1-METHYL-5-PHENYL-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE
CAS:Purezza:95.0%Colore e forma:SolidPeso molecolare:265.3160095214844Defluoro 8-Hydroxy Flumazenil
CAS:Prodotto controllatoFormula:C15H15N3O4Colore e forma:NeatPeso molecolare:301.30(R)-3-amino-9-fluoro-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
Purezza:97%Peso molecolare:269.27899169921875Ref: 10-F790109
1gPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta250mgPrezzo su richiesta2H-1,4-Benzodiazepin-2-one, 3-amino-1,3-dihydro-5-phenyl-, (3S)-
CAS:Purezza:98%Peso molecolare:251.289Cloxazolam
CAS:Prodotto controllato<p>Applications Cloxazolam is a benzodiazepine derivative with anxiolytic, hypnotic and antihypertensive properties used as an anti-anxiety drug. It is metabolized into the active metabolite Delorezepam (D230675). Controlled Substance.<br>References Oliveira-Silva, D. et al.: Biomed. Chrom., 23, 1266 (2009); Kamioka, T. et al.: Psychopharmacol., 52, 17 (1977); Fischer-Cornelssen, K.A. et al.: Arzneim.-Forsch., 31, 1757 (1981);<br></p>Formula:C17H14Cl2N2O2Colore e forma:NeatPeso molecolare:349.213-Amino-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
CAS:Purezza:95.0%Peso molecolare:251.289001464843757-bromo-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Purezza:95.0%Peso molecolare:315.17001342773447-methyl-5-phenyl-1,3,4,5-tetrahydro-2H-benzo[e][1,4]diazepin-2-one
CAS:Purezza:95.0%Peso molecolare:252.317001342773444-(2-Benzoyl-4-chlorophenyl)-5-methyl-4H-1,2,4-triazole-3-carboxaldehyde
CAS:Prodotto controllatoFormula:C17H12ClN3O2Colore e forma:NeatPeso molecolare:325.758-Chloro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester
CAS:Prodotto controllato<p>Impurity Flumazenil EP Impurity F<br>Applications 8-Chloro-5,6-dihydro-5-methyl-6-oxo-4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic Acid Ethyl Ester is an impurity of Flumazenil (F500450), an imidazodiazepine which selectively blocks the central effects of classic benzodiazepines.<br>References Hunkeler, W., et al.: Nature, 290, 514 (1981), Pole, P., et al.: Arch. Pharmacol., 316, 317 (1981), Timm, U., et al.: Arzneim.-Forsch., 33, 358 (1983),<br></p>Formula:C15H14ClN3O3Colore e forma:NeatPeso molecolare:319.743-Amino-6-bromo-4-(2-pyridinyl)-2(1H)-quinolinone(>90%)
CAS:Prodotto controllato<p>Stability Air Sensitive<br>Applications 3-Amino-6-bromo-4-(2-pyridinyl)-2(1H)-quinolinone is an impurity of Bromazepam (B678500); a controlled substance (depressant) and anxiolytic.<br>References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973); Chalmers, P., et al.: Anesthesia, 39, 370 (1984); Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987)<br></p>Formula:C14H10BrN3OPurezza:>90%Colore e forma:Light Brown To BrownPeso molecolare:316.15Alprazolam 5-Oxide
CAS:Prodotto controllato<p>Applications A metabolite of Alprazolam (A575650).<br>References Schwartz, M.A., et al.: J. Pharmacol. Exp. Ther., 149, 423 (1965), Childress, S.J., et al.: J. Pharm. Sci., 53, 577 (1964), Gall, M., et al.: J. Med. Chem., 21, 1290 (1978)<br></p>Formula:C17H13ClN4OColore e forma:NeatPeso molecolare:324.767-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione
CAS:Prodotto controllato<p>Applications 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione (cas# 4547-02-8) is a positive allosteric modulator for the muscarinic M1 receptor, which could be a potential treament for the Alzheimer's disease or Schizophrenia.<br>References Flohr, A., et al.: Bioorg. Med. Chem. Lett., 27, 5415 (2017)<br></p>Formula:C15H11ClN2SColore e forma:BeigePeso molecolare:286.7792Bromazepam-d4
CAS:Prodotto controllato<p>Applications Controlled substance (depressant). Anxiolytic. Labelled Bromazepam.<br>References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),<br></p>Formula:C142H4H6BrN3OColore e forma:NeatPeso molecolare:320.18Clobazam-13C6 (1 mg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C6C10H13ClN2O2Colore e forma:ColourlessPeso molecolare:306.702-Amino-5-nitro-2'-chlorobenzophenone
CAS:<p>Impurity Clonazepam EP Impurity A<br>Applications 2-Amino-5-nitro-2'-chlorobenzophenone (Clonazepam EP Impurity A) is an impurity of Clonazepam (C587080).<br></p>Formula:C13H9ClN2O3Colore e forma:NeatPeso molecolare:276.68Flunitrazepam
CAS:Prodotto controllato<p>Applications Flunitrazepam is used as an hypnotic. This is a controlled substance (depressant).<br>References Sternbach, L.H., et al.: J. Med. Chem., 6, 261 (1963), Eidelberg, E., et al.: Neurology, 5, 223 (1965), Caplan, Y., et al.: J. Anal. Toxicol., 25, 396 (2001), Wood, M., et al.: Forensic Sci. Int., 150, 227 (2005),<br></p>Formula:C16H12FN3O3Colore e forma:Off-WhitePeso molecolare:313.283-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone (Clonazepam Impurity)
CAS:<p>Impurity Clonazepam EP Impurity B<br>Applications 3-Amino-4-(2-chlorophenyl)-6-nitro-2(1H)-quinolinone (Clonazepam EP Impurity B) is an impurity of Clonazepam (C587080), antiepileptic agent with anxiolytic and antimanic properties.<br>References Mayer, W., et al.: Pharmazie, 29, 700 (1974), Blum, et al.: Arzneim.-Forsch., 23, 377 (1973), Winslow, W.C., et al.: Anal. Profiles Drug Subs., 6, 61 (1977)<br></p>Formula:C15H10ClN3O3Colore e forma:Yellow BrownPeso molecolare:315.717-Amino Clonazepam
CAS:Prodotto controllato<p>Applications The major metabolite of Clonazepam (C587080).<br>References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),<br></p>Formula:C15H12ClN3OColore e forma:YellowPeso molecolare:285.73Methyl Clonazepam
CAS:Prodotto controllato<p>Applications Shows sedative and anxiolytic properties. Impairment of psychomotor performance reported. Activity blocked by flumazenil.<br>References Doumont, A., et al.: Psychopharmacology, 87, 130 (1985), Psychopharmacology, 94(4), 501 (1988)<br></p>Formula:C16H12ClN3O3Colore e forma:YellowPeso molecolare:329.74Alprazolam
CAS:Prodotto controllato<p>Applications Controlled substance (depressant). Anxiolytic.<br>References Sethy, V.H., et al.: Arch. Pharmacol., 301, 157 (1978), Fawcett, J.A., et al.: Pharmacotherapy, 2, 242 (1982),<br></p>Formula:C17H13ClN4Colore e forma:White To Off-WhitePeso molecolare:308.76Bromazepam
CAS:Prodotto controllato<p>Applications Controlled substance (depressant). Anxiolytic.<br>References Schwartz, M.A., et al.: J. Pharm. Sci., 62, 1776 (1973), Chalmers, P., et al.: Anesthesia, 39, 370 (1984), Hassan, M.M., et al.: Anal. Profiles Drug Subs., 16, 1 (1987),<br></p>Formula:C14H10BrN3OColore e forma:WhitePeso molecolare:316.15N-Desmethyl Clobazam
CAS:Prodotto controllato<p>Applications N-Desmethyl Clobazam is an impurity of Clobazam (C582500), which is a benzodiazepine, psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types and is an anxiolytic, anticonvulsant and controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C15H11ClN2O2Colore e forma:Off-WhitePeso molecolare:286.71Flumazenil Carboxylic Acid
CAS:<p>Applications Flumazenil carboxylic acid is a derivative of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.<br>References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)<br></p>Formula:C13H10FN3O3Colore e forma:NeatPeso molecolare:275.24Clobazam
CAS:Prodotto controllato<p>Applications Benzodiazepine psychotherapeutic agent. Clobazam (CLB) has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant. Controlled substance (depressant).<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979), Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990), Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C16H13ClN2O2Colore e forma:WhitePeso molecolare:300.74Nitrazepam-d5
CAS:Prodotto controllatoFormula:C152H5H6N3O3Colore e forma:Off-White To Light YellowPeso molecolare:286.30(3,4-Dimethoxyphenyl)(2-(2-hydrazonopentan-3-yl)-4,5-dimethoxyphenyl)methanone
CAS:Prodotto controllatoFormula:C22H28N2O5Colore e forma:Off WhitePeso molecolare:400.47Alprazolam Aminomethyl Ketone Hydrochloride
CAS:Prodotto controllato<p>Applications Alprazolam (A575650) impurity.<br>References Hirai, K., et al.: J. Med. Chem., 24, 20 (1981),<br></p>Formula:C17H16Cl2N4O·xHClColore e forma:White To Light YellowPeso molecolare:363.24Flumazenil-D5
CAS:Prodotto controllato<p>Applications Flumazenil-D5 is a labelled analogue of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.<br>References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)<br></p>Formula:C15H9D5FN3O3Colore e forma:NeatPeso molecolare:303.29Clobazam impurity D
<p>Clobazam impurity D is a natural metabolite of clobazam. It is a white crystalline solid that is soluble in methanol, ethanol, and dichloromethane. Clobazam impurity D has been shown to be an analytical standard for HPLC analysis. It has also been used as a reference material for the pharmacopoeia, which is a publication that sets standards for purity or strength of chemicals and drugs. Clobazam impurity D is synthesized by the reaction of 3-chloro-2-(2-oxopyrrolidin-1-yl)benzamide with N,N-dimethylformamide dimethyl acetal.</p>Formula:C18H17ClN2O2Purezza:Min. 95%Peso molecolare:328.79 g/mol7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C9H11ClN2Purezza:95%Colore e forma:SolidPeso molecolare:182.654-Boc-8-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H19FN2O2Purezza:98%Colore e forma:SolidPeso molecolare:266.3164-Boc-7-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H19ClN2O2Purezza:97%Peso molecolare:282.77Tert-butyl 2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepine-1-carboxylate
CAS:Purezza:95%Peso molecolare:248.3260047-methoxy-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Purezza:98%Peso molecolare:220.22799687-Chloro-1-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Purezza:98%Peso molecolare:224.63999944-Boc-7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C16H24N2O4Purezza:97.0%Peso molecolare:308.3787-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C10H14N2Purezza:97.0%Colore e forma:SolidPeso molecolare:162.2364-Boc-7-Hydroxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H20N2O3Purezza:97.0%Peso molecolare:264.3259-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C10H14N2Purezza:97.0%Peso molecolare:162.2367-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
CAS:Formula:C10H9FN2O2Purezza:97%Peso molecolare:208.1928-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C9H11FN2Purezza:97.0%Peso molecolare:166.1994-Boc-7-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H19FN2O2Purezza:97.0%Colore e forma:SolidPeso molecolare:266.3164-Boc-9-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H19ClN2O2Purezza:97.0%Peso molecolare:282.777,8-Dimethoxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C11H16N2O2Purezza:97.0%Peso molecolare:208.2617-Amino-4-Boc-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H21N3O2Purezza:95%Peso molecolare:263.3418-Chloro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Formula:C9H7ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:210.629-CHLORO-3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE
CAS:Formula:C9H7ClN2O2Purezza:97.0%Peso molecolare:210.629-amino-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one
CAS:Formula:C9H11N3OPurezza:95%Peso molecolare:177.2077-AMINO-4-BOC-4,5-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-2(3H)-ONE
CAS:Formula:C14H19N3O3Purezza:97.0%Peso molecolare:277.3247-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Formula:C9H7BrN2O2Purezza:97%Colore e forma:SolidPeso molecolare:255.0717-BROMO-2,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPINE HCL
CAS:Formula:C9H12BrClN2Purezza:95.0%Peso molecolare:263.564-Boc-8-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H19ClN2O2Purezza:97.0%Peso molecolare:282.777-Bromo-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Purezza:95+%Peso molecolare:269.09799191-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Formula:C10H10N2O2Purezza:95.0%Colore e forma:SolidPeso molecolare:190.2023,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS:Formula:C9H8N2O2Purezza:98%Colore e forma:SolidPeso molecolare:176.1754-Boc-7-Bromo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H19BrN2O2Purezza:97.0%Colore e forma:SolidPeso molecolare:327.2222,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepin-7-ol
CAS:Formula:C9H12N2OPurezza:97.0%Peso molecolare:164.2084-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS:Formula:C10H10N2O2Purezza:95.0%Peso molecolare:190.2027-Fluoro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C9H11FN2Purezza:95%Colore e forma:SolidPeso molecolare:166.1999-Nitro-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Formula:C9H9N3O3Purezza:95.0%Peso molecolare:207.1898-Amino-4-Boc-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H21N3O2Purezza:97%Peso molecolare:263.3417-Fluoro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS:Formula:C9H7FN2O2Purezza:97.0%Colore e forma:SolidPeso molecolare:194.1654-Boc-2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C14H20N2O2Purezza:97.0%Colore e forma:SolidPeso molecolare:248.3264-Boc-9-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C15H22N2O2Purezza:97.0%Peso molecolare:262.3538-Chloro-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C9H11ClN2Purezza:97.0%Colore e forma:SolidPeso molecolare:182.653-(Piperidin-4-yl)-1,3,4,5-tetrahydro-2H-benzo[d][1,3]diazepin-2-one
CAS:Purezza:97%Peso molecolare:245.3260044-Boc-7-Methyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C15H22N2O2Purezza:97.0%Peso molecolare:262.3532,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine
CAS:Formula:C9H12N2Purezza:97.0%Colore e forma:White to yellow/orange crystalline powderPeso molecolare:148.2098-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS:Formula:C9H9BrN2OPurezza:97.0%Peso molecolare:241.0881,2,4,5-Tetrahydro-benzo[e][1,4]diazepin-3-one
CAS:Formula:C9H10N2OPurezza:97.0%Colore e forma:SolidPeso molecolare:162.1922,3,4,5-TETRAHYDRO-1H-BENZO[E][1,4]DIAZEPIN-8-YLAMINE 2HCL
CAS:Formula:C9H15Cl2N3Purezza:97.0%Peso molecolare:236.143-Amino-4-(2-fluorophenyl)-1-methyl-6-nitroquinolin-2(1H)-one
CAS:Prodotto controllatoFormula:C16H12FN3O3Colore e forma:NeatPeso molecolare:313.283-Methyl Clobazam
CAS:Prodotto controllato<p>Applications 3-Methyl Clobazam is a metabolite of Clobazam (C582500), a benzodiazepine psychotherapeutic agent that has proven efficacy against multiple seizure types. An anxiolytic; anticonvulsant.<br>References Gastaut, H., et al.: Epilepsia, 20, 437 (1979); Guberman, A., et al.: Can J. Neurol. Sci., 17, 311 (1990); Munn, R., et al.: Pediatr. Neurol. 9, 465 (1993)<br></p>Formula:C17H15ClN2O2Colore e forma:NeatPeso molecolare:314.773,3-Dimethyl Clobazam
Prodotto controllatoFormula:C18H17ClN2O2Colore e forma:NeatPeso molecolare:328.792-(2-Aminoacetamido)-5-nitro-2'-chlorobenzophenone Hydrochloride (Clonazepam Impurity)
CAS:Prodotto controllatoFormula:C15H12ClN3O4·ClHColore e forma:WhitePeso molecolare:370.18747-Aminonorflunitrazepam
CAS:Prodotto controllatoFormula:C15H12FN3OColore e forma:Light YellowPeso molecolare:269.27N,N-Dimethylformamide Diethyl Acetal
CAS:Prodotto controllato<p>Stability Moisture Sensitive<br>Applications N,N-Dimethylformamide Diethyl Acetal is used as a reagent in the design of EGF-R tyrosine kinase inhibitors. Also used in the synthesis of aminopyridine derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Traxler, P. et al.: J. Med. Chem., 40, 3601 (1997); Cheikh, N. et al.: Tetrahedron, 69, 1234 (2013);<br></p>Formula:C7H17NO2Colore e forma:NeatPeso molecolare:147.22Flumazenil Carboxylic Acid-D3
Prodotto controllato<p>Applications Flumazenil Carboxylic Acid-D3 is an isotope labelled form of Flumazenil Carboxylic Acid (F500455); a derivative of Flumazenil (F500455), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.<br>References Brogden, R. & Goa, K.: Drugs, 35, 448 (1988); Klotz, U. & Kanto, J.: Clin. Pharmacokinet., 14, 1 (1988)<br></p>Formula:C13H7D3FN3O3Colore e forma:NeatPeso molecolare:278.252-Amino-5-nitrobenzophenone
CAS:Prodotto controllatoFormula:C13H10N2O3Colore e forma:NeatPeso molecolare:242.233-Amino-6-chloro-3,4-dihydro-2-methyl-4-phenyl-4-quinazolinol
CAS:Prodotto controllatoFormula:C15H14ClN3OColore e forma:NeatPeso molecolare:287.742-(2-Acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine
CAS:Prodotto controllato<p>Applications 2-(2-Acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine is an impurity of Alprazolam (A575650.<br>References Hester, J.B., et al.: J. Org. Chem., 44, 2688, (1979); Anjaneyulu, Y., et al.: Asian. J. Chem., 19, 3375 (2007);<br></p>Formula:C17H15ClN4OColore e forma:White To Off-WhitePeso molecolare:326.782-Bromo-N-[4-bromo-2-(2-pyridinylcarbonyl)phenyl]-acetamide
CAS:Prodotto controllato<p>Applications 2-Bromo-N-[4-bromo-2-(2-pyridinylcarbonyl)phenyl]-acetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>Formula:C14H10Br2N2O2Colore e forma:NeatPeso molecolare:398.05N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide
CAS:Prodotto controllato<p>Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).<br>References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)<br></p>Formula:C14H10BrClN2O2Colore e forma:Light Yellow To BeigePeso molecolare:353.60Alprazolam 5,6-Epoxide
CAS:Prodotto controllato<p>Applications Alprazolam derivative.<br>References Hester, J. et al., J. of Med. Chem. 23, 643 (1980)<br></p>Formula:C17H13ClN4OColore e forma:NeatPeso molecolare:324.772-(2-Amino-5-bromobenzoyl)pyridine
CAS:<p>2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval</p>Formula:C12H9BrN2OPurezza:Min. 95%Peso molecolare:277.12 g/molClobazam CIV
CAS:Prodotto controllatoClobazam (inn) and methyprylon (inn)Formula:C16H13ClN2O2Colore e forma:White Crystalline PowderPeso molecolare:300.066567-Amino Clonazepam-d4
CAS:Prodotto controllato<p>Applications A labelled major metabolite of Clonazepam (C587080).<br>References Clark, D., et al.: Drugs, 29, 342 (1985), Colmenero, J., et al.: Antimicrob. Agents Chemother., 38, 2798 (1994), Grant, D., et al.: Pharmacology, 61, 204 (2000), Negrusz, A., et al.: Anal. Bioanal. Chem., 376, 1198 (2003),<br></p>Formula:C152H4H8ClN3OColore e forma:NeatPeso molecolare:289.75
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