Steroidi e Derivati
Gli steroidi sono composti organici con una struttura a quattro anelli fusi, nota come nucleo steroideo. Questo nucleo può essere legato a vari gruppi funzionali che ne modificano le proprietà e le funzioni biologiche. Gli steroidi svolgono un ruolo chiave nella regolazione dei processi metabolici e ormonali. Sono utilizzati in medicina per il trattamento di disturbi infiammatori, malattie autoimmuni e squilibri ormonali. Inoltre, alcuni derivati degli steroidi possiedono potenti proprietà antinfiammatorie, come i corticosteroidi. In terapie specifiche, vengono impiegati per ridurre l’infiammazione e controllare il dolore in diverse patologie.
Presso CymitQuimica, offriamo una varietà di steroidi e loro derivati per la ricerca e lo sviluppo farmaceutico.
Trovati 4973 prodotti di "Steroidi e Derivati"
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(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:Prodotto controllato<p>Applications (6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an intermediate in the synthesis of Paramethasone Acetate (P191845), a derivative of Dexamethasone (D298800), a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formula:C24H29FO6Colore e forma:Off-WhitePeso molecolare:432.48(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (Bimatoprost Impurity)
CAS:Prodotto controllatoFormula:C18H24O4Colore e forma:NeatPeso molecolare:304.38N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride
CAS:Prodotto controllato<p>Applications N-Des(1,1-dimethylethyl) N-Cyclohexyl Finasteride is an impurity of Finasteride (F342000); an inhibitor of 5α-reductase which is the enzyme that converts testosterone to the more potent androgen 5α-dihydrotestosterone.Also an antialopecia agent.<br>References Koronkowski, M.J., et al.: Pharmacotherapy, 13, 309 (1993); Tenover, J.L., et al.: Clin. Ther., 19, 243 (1997); McConnell, J.D., et al.: N. Engl. J. Med., 338, 557 (1998)<br></p>Formula:C25H38N2O2Colore e forma:NeatPeso molecolare:398.586b-Methyl Fluorometholone
CAS:Prodotto controllato<p>Stability Not stable in Acidic or basic condition<br>Applications 6β-Methyl Fluorometholone is an impurity in the synthesis of Fluorometholone (F593145), a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Formula:C22H29FO4Colore e forma:NeatPeso molecolare:376.46Travoprost 13,14-Epoxide (Mixture of Diastereomers)
Prodotto controllato<p>Stability Temperature Sensitive<br>Applications An epoxy impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600).<br></p>Formula:C26H35F3O7Colore e forma:NeatPeso molecolare:516.353β-Hydroxy Tibolone (1mg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C21H30O2Colore e forma:Single SolutionPeso molecolare:314.46Testosterone-13C
CAS:Prodotto controllatoFormula:C1813CH28O2Colore e forma:NeatPeso molecolare:289.42Mexrenone
CAS:Prodotto controllato<p>Applications Mexrenone is an impurity of eplerenon (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.<br>References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),<br></p>Formula:C24H32O5Colore e forma:Off-WhitePeso molecolare:400.50791,2-Dihydro Triamcinolone
CAS:Prodotto controllato<p>Applications 1,2-Dihydro Triamcinolone is a derivative of Triamcinolone (T767165), a glucocorticoid, antiasthmatic (inhalant); antiallergic (nasal).<br>References Florey, K., et al.: Anal. Profiles Drug Subs., 1, 397 (1972); Bernstein, I.L., et al.: Chest, 81, 20 (1982);<br></p>Formula:C21H29FO6Colore e forma:NeatPeso molecolare:396.45Tasimelteon
CAS:<p>Applications Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. It helps to correct the circadian rhythm disorder often seen in patients who are visually impaired.<br>References Lahon, J. et al.: World. J. Pharm. Res., 3, 1521 (2014);<br></p>Formula:C15H19NO2Colore e forma:NeatPeso molecolare:245.3169Fluticasone-d3 17β-Carboxylic Acid
CAS:Prodotto controllatoFormula:C21H23D3F2O5Colore e forma:NeatPeso molecolare:399.44Testosterone-16,16,17-d3 3-Phenylpropionate
CAS:Prodotto controllato<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>Formula:C28H33D3O3Colore e forma:NeatPeso molecolare:423.607α-Acetylthio-17α-ethoxymethyl Testosterone
CAS:Prodotto controllatoFormula:C24H36O4SColore e forma:NeatPeso molecolare:420.61Estradiol 3-Propyl Ether
CAS:Prodotto controllatoFormula:C21H30O2Colore e forma:NeatPeso molecolare:314.46E-Ospemifene
CAS:Prodotto controllato<p>Applications E-Ospemifene is the E-isomer of Ospemifene (O703000) and is useful for lowering serum cholesterol. It acts as a antiatherosclerotic and is also estrogen-like.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sodervall, M., et al.: PCT Int. Appl. WO 9942427 A1 19990826. Aug 26, 1999<br></p>Formula:C24H23ClO2Colore e forma:NeatPeso molecolare:378.892-Methyl Ethynyl Estradiol
CAS:Prodotto controllato<p>Impurity Ethinylestradiol EP Impurity M<br>Applications 2-Methylethynylestradiol (Ethinylestradiol EP Impurity M) is a 17α-ethynyl steroid. 2-Methylethynylestradiol is an impurity of Ethynylestradiol (E685100).<br></p>Formula:C21H26O2Colore e forma:NeatPeso molecolare:310.43Tetrahydrocortisol 21-Acetate
CAS:Prodotto controllato<p>Applications Cortisol derivative. A potential corticoid metabolite.<br>References Okihara, R. et al.; Chem. Pharm. Bull. 58, 344 (2010); Hosoda, H. et al.; Chem. Pharm. Bull. 32, 4023 (1984)<br></p>Formula:C23H36O6Colore e forma:NeatPeso molecolare:408.53Betamethasone 21-Acetate
CAS:Prodotto controllato<p>Applications Betamethasone acetate (BA) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001), Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003), Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007),<br></p>Formula:C24H31FO6Colore e forma:WhitePeso molecolare:434.50Tixocortol (>90%)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.<br>References Torossian, D.R., et al.: Arzneim.-Forsch., 31, 453 (1981),<br></p>Formula:C21H30O4SColore e forma:NeatPeso molecolare:378.536α-Hydroxy Gestrinone Glucuronide
CAS:Prodotto controllatoFormula:C27H32O9Colore e forma:Light YellowPeso molecolare:500.546a,9a-Difluoroprednisolone
CAS:Prodotto controllato<p>Applications 6α,9α-Difluoroprednisolone has shown to increase metastases and increase glucocorticoid activity in C57/BL6 mice.<br>References Albert, D., Zeidman, I.: Cancer Res., 22, 1297 (1962)<br></p>Formula:C21H26F2O5Colore e forma:White To Light BeigePeso molecolare:396.426α-Chloro-17-acetoxy Progesterone
CAS:<p>Applications Progesterone (P755900) impurity.<br>References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),<br></p>Formula:C23H31ClO4Colore e forma:NeatPeso molecolare:406.943Estradiol 3-heptanoate
CAS:Prodotto controllatoFormula:C25H36O3Colore e forma:NeatPeso molecolare:384.55Fluocinolone Acetonide-13C3
CAS:Prodotto controllatoFormula:C2113C3H30F2O6Colore e forma:NeatPeso molecolare:455.471-Dehydro Aldosterone
CAS:Prodotto controllatoFormula:C21H26O5Colore e forma:NeatPeso molecolare:358.433-O-Benzyl Estriol
CAS:Prodotto controllato<p>Applications Protected Estriol.<br>References Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),<br></p>Formula:C25H30O3Colore e forma:NeatPeso molecolare:378.50Testosterone 17-O-Acetate-d3 (1mg/ml in Acetonitrile)
CAS:Prodotto controllatoFormula:C21H27D3O3Colore e forma:ColourlessPeso molecolare:333.48Ulipristal
CAS:Prodotto controllato<p>Applications Ulipristal is a selective progesterone receptor modulator. Ulipristal is used as an emergency contraceptive.<br>References Gronemeijer, H., et al.: J. Steroid Biochem., 40, 271 (1991), Spitz, I., et al.: Contraception, 48, 403 (1993), Conneely, O., et al.: Steroids, 68, 771 (2003), Chwalisz, K., et al.: Endocr. Rev., 26, 423 (2005),<br></p>Formula:C28H35NO3Colore e forma:NeatPeso molecolare:433.582-Hydroxy-estrone-6-N3-adenine (90%)
CAS:Prodotto controllato<p>Applications 2-Hydroxy-estrone-6-N3-adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Formula:C23H25N5O3Purezza:90%Colore e forma:NeatPeso molecolare:419.4811b-Hydroxy Etiocholanolone
CAS:Prodotto controllato<p>Applications A metabolite of Etiocholanolone.<br>References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),<br></p>Formula:C19H30O3Colore e forma:White To Off-WhitePeso molecolare:306.4418-Methyl Ethynyl Estradiol
CAS:Prodotto controllatoFormula:C21H26O2Colore e forma:NeatPeso molecolare:310.42994β-Hydroxy Cholesterol
CAS:Prodotto controllato<p>Applications A metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Formula:C27H46O2Colore e forma:White To Light BeigePeso molecolare:402.65Cholesterol 5α,6α-Epoxide
CAS:Prodotto controllato<p>Applications Cholesterol 5alpha,6alpha-epoxide is used in the generation of oxysterols and in the studies of the biological significance of oxysterols.<br>References Lizard, G., et al.: Eur. J. Lipid Sci. Technol., 118, 135 (2016); Sabolova, M., et al.: J. Sci. Food Agric., 97, 5092 (2017); Bezine, M., et al.: Biochimie (2018)<br></p>Formula:C27H46O2Colore e forma:NeatPeso molecolare:402.65Dexamethasone b-D-Glucuronide Sodium (>90%)
CAS:Prodotto controllato<p>Applications Sodium salt of Dexamethasone β-D-Glucuronide is a potential prodrug for colonic delivery of the antiinflammatory corticosteroid Dexamethasone.<br>References Fotsis, T., et al.: J. Steroid Biochem., 14, 457 (1981), Choi, M., et al.: Steroids, 65, 54 (2000); Haeberlin, B. et al.: Pharm Res., 10, 1553 (1993);<br></p>Formula:C28H36FNaO11Colore e forma:NeatPeso molecolare:590.57(E/Z)-17-Deacetylnorgestimate
CAS:Prodotto controllatoFormula:C21H29NO2Colore e forma:NeatPeso molecolare:327.46Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Formula:C33H33FN2O6Colore e forma:NeatPeso molecolare:572.623-Aminobenzotrifluoride
CAS:Prodotto controllato<p>Applications 3-Aminobenzotrifluoride is a known human toxin that can cause bacterial mutation and hepatocyte unscheduled DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reinhold, D., et al.: T. ASAE, 49, 2077 (2006); Thompson, C., et al.: Environ. Mutagen., 5, 803 (1983)<br></p>Formula:C7H6F3NColore e forma:YellowPeso molecolare:161.126b-Chloro-7a-hydroxy-6,7-dihydro Cyproterone Acetate
CAS:Prodotto controllato<p>(1β,2β,6β-7α)-17-(Acetyloxy)-6-chloro-1,2-dihydro-7-hydroxy<br>-3'H-cyclopropa[1,2]pregna-1,4-diene-3,20-dione; 6β-Chloro<br>-1β,2β-dihydro-7α,17-dihydroxy-3'Hcyclopropa[1,2]pregna-1,4-diene-3,20-dione 17-Acetate;<br>Cyproterone Acetate EP Impurity G</p>Formula:C24H31ClO5Colore e forma:NeatPeso molecolare:434.953Testosterone-d8
CAS:Prodotto controllato<p>Applications Labelled Testosterone (T155000). Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol.Controlled substance (anabolic steroid). Androgen.<br>References McFarland, K., et al.: Science, 245, 494 (1989), Heckert, L., et al.: Mol. Endocrinol., 12, 1499 (1998), Themmen, A., et al.: Endocr. Rev. 21, 551 (2000), Kumar, R., et al.: Biol. Reprod., 65, 710 (2001),<br></p>Formula:C19H20D8O2Colore e forma:White To Off-WhitePeso molecolare:296.47Digitoxigenin Mono-β-D-digitoxoside
CAS:Prodotto controllatoFormula:C29H44O7Colore e forma:White To Off-WhitePeso molecolare:504.666-Keto Dexamethasone
Prodotto controllato<p>Applications 6-keto Dexamethasone, is an impurity of Dexamethasone, a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br></p>Formula:C22H27FO6Colore e forma:NeatPeso molecolare:406.4417α-Hydroxyprogesterone Heptanoate
CAS:<p>Applications 17α-Hydroxyprogesterone Heptanoate can be used in therapeutic use and biological study of pharmaceutical compounds and methods of use thereof for treating gender-biased immune disorders.<br>References Stoloff, G., et al.: PCT Int. Appl. WO 2016005599 A1 20160114 (2016)<br></p>Formula:C28H42O4Colore e forma:NeatPeso molecolare:442.63Testosterone Oleate
CAS:Prodotto controllatoFormula:C37H60O3Colore e forma:NeatPeso molecolare:552.87Betamethasone 21-Mesylate (>90%)
CAS:Prodotto controllatoFormula:C23H31FO7SPurezza:>90%Colore e forma:NeatPeso molecolare:470.5517α,21-Dideoxy-6α,9α-Difluoroprednisolone
CAS:Prodotto controllato<p>Applications 17α,21-Dideoxy-6α,9α-Difluoroprednisolone is an impurity of the drug Difluprednate (D445925). Difluprednate is a corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.<br>References Kapp, A., et al.: J. Allergy and Clin. Immunol., 110, 277 (2002); Yasueda, S., et al.: J. Pharm. Biomed. Anal., 30, 1735 (2003); Yamaguchi, M., et al.: Int. J. Pharm., 301, 121 (2005)<br></p>Formula:C20H24F2O4Colore e forma:NeatPeso molecolare:366.4(5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one
CAS:Prodotto controllato<p>Applications (5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one is metabolite and impurity of the anabolic steroid Oxandrolone (O845050).<br>References Fragkaki, A.G. et al.: J. Steroid Biochem. Mol. Biol., 115, 44 (2009); Bi, H. et al.: J. Steroid Biochem. Mol. Biol., 42, 533 (1992);<br></p>Formula:C19H28O2Colore e forma:White To Off-WhitePeso molecolare:288.427-[9-[[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17β
Prodotto controllato<p>Applications Fulvestrant (F862500) impurity C.<br></p>Formula:C41H65F5O4S2Colore e forma:NeatPeso molecolare:781.0713β-Ethyl-11-methylenegon-4-en-17-one
CAS:Prodotto controllato<p>Applications Desogestrel intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bergink, E., et al.: J. Steroid Biochem., 14, 175 (1981), Phillips, A., et al.: Contraception, 36, 181 (1987)<br></p>Formula:C20H28OColore e forma:NeatPeso molecolare:284.44Carbenoxolone
CAS:Prodotto controllato<p>Applications Carbenoxolone<br></p>Formula:C34H50O7Colore e forma:NeatPeso molecolare:570.762-Hydroxy Estradiol 6-N3-Adenine
CAS:Prodotto controllato<p>Applications 2-Hydroxy Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.<br>References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)<br></p>Formula:C23H27N5O3Colore e forma:NeatPeso molecolare:421.49
![(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxy-5-phenylpent-1-enyl)hexahydro-2H-cyclopenta[b]furan-2,5-diol (B…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH294735.webp&w=3840&q=75)
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