Steroidi e Derivati
Gli steroidi sono composti organici con una struttura a quattro anelli fusi, nota come nucleo steroideo. Questo nucleo può essere legato a vari gruppi funzionali che ne modificano le proprietà e le funzioni biologiche. Gli steroidi svolgono un ruolo chiave nella regolazione dei processi metabolici e ormonali. Sono utilizzati in medicina per il trattamento di disturbi infiammatori, malattie autoimmuni e squilibri ormonali. Inoltre, alcuni derivati degli steroidi possiedono potenti proprietà antinfiammatorie, come i corticosteroidi. In terapie specifiche, vengono impiegati per ridurre l’infiammazione e controllare il dolore in diverse patologie.
Presso CymitQuimica, offriamo una varietà di steroidi e loro derivati per la ricerca e lo sviluppo farmaceutico.
Trovati 4973 prodotti di "Steroidi e Derivati"
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Dexamethasone Oxetanone
CAS:Prodotto controllato<p>Applications Dexamethasone Oxetanone is a potent antiglucocorticoid.<br>References Lamontagne, N., et al.: Endocrinology, 114, 2252 (1984);<br></p>Formula:C22H27FO4Colore e forma:NeatPeso molecolare:374.45Atorvastatin Lactone Diepoxide(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An Atorvastatin (A791750) derivative which have improved stability.<br></p>Formula:C33H33FN2O6Colore e forma:NeatPeso molecolare:572.626-Deschloro Cyproterone Acetate
CAS:Prodotto controllato<p>(1β,2β)-17-(Acetyloxy)-1,2-dihydro-3'H-cyclopropa[1,2]pregna<br>-1,4,6-triene-3,20-dione; 17-Hydroxy-1 ,2 -methylenepregna<br>-4,6-diene-3,20-dione Acetate; Cyproterone Acetate EP<br>Impurity A<br></p>Formula:C24H30O4Colore e forma:NeatPeso molecolare:382.4934'-Nitro-3'-(trifluoromethyl)acetanilide
CAS:<p>Applications 4’-Nitro-3’-(trifluoromethyl)acetanilide is a metabolite of the nonsteroidal antiandrogen drug, Flutamide (F598850).<br>References Kang, P. et al.: Drug Metab. Dispos., 36, 1425 (2008); Takashima, E. et al.: Biol. Pharmac. Bull., 26, 1455 (2003); Katchen, B. et al.: J. Invest. Dermatol., 66, 379 (1976);<br></p>Formula:C9H7F3N2O3Colore e forma:NeatPeso molecolare:248.16Desisobutyryl Ciclesonide
CAS:Prodotto controllato<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formula:C28H38O6Colore e forma:White To Off-WhitePeso molecolare:470.60a,a,a-Trifluorotoluene
CAS:Prodotto controllato<p>Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);<br></p>Formula:C7H5F3Colore e forma:ColourlessPeso molecolare:146.11(3E)-17-Deacetylnorgestimate
CAS:<p>Applications E-17-Deacetylnorgestimate is a metabolite of Norgestimate. A contraceptive for birth control used by women.Note- The oxime isomerizes when: 1) Heated in any solvent or heating the crystalline form 2) Dissolved in MeOH at room temperature very quickly 3) Dissolved in acetone or CHCl3 at room temperature in a couple of hours at room temperature4) In EtOAc or EtOAc/isooctane over a couple of days at RT. It is stable in the crystalline form.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990); Rabiolo, A., et al.: Arch. Gynecol. Obstet., 294, 1317 (2016)<br></p>Formula:C21H29NO2Colore e forma:Off-WhitePeso molecolare:327.4620-Hydroxydexamethasone
CAS:Prodotto controllatoFormula:C22H31FO5Colore e forma:NeatPeso molecolare:394.486-Oxo Boldione
CAS:Prodotto controllato<p>Applications A derivative of Exemestane (E957000), a new aromatase inhibitor.<br>References Thompson, E., et al.: J. Biol. Chem., 249, 5364 (1974), Cole, P., et al.: J. Med. Chem., 33, 2933 (1990), Buzzetti, F., et al.: Steroids, 58, 527 (1993),<br></p>Formula:C19H22O3Colore e forma:Off-White To Light YellowPeso molecolare:298.383-Oxo-4-aza-5-androstene-17β-carboxylic Acid
CAS:Prodotto controllatoFormula:C19H27NO3Colore e forma:NeatPeso molecolare:317.42(11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:Prodotto controllato<p>Stability Moisture Sensitive<br>Applications (11β,16α)-9-Bromo-21-[(ethoxycarbonyl)oxy]-11-(formyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an impurity of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent.<br>References Spangler, M., et al.: Chromatographia, 54(5/6), 329-334 (2001);Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995)<br></p>Formula:C26H33BrO8Colore e forma:NeatPeso molecolare:553.443β,5α-Tetrahydrodeoxycorticosterone
CAS:<p>Applications 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons.<br>References Hamilton, N.M., et al.: J. Medn. Chem., 55, 4431 (2012); Ffench, M., et al.: Steriods., 64, 76 (1999);<br></p>Formula:C21H34O3Colore e forma:White To Off-WhitePeso molecolare:334.49D-Homoanalog of Triamcinolone
CAS:Prodotto controllato<p>Applications D-Homoanalog of Triamcinolone is a rearrangement product of the drug triamcinolone, an anti-inflammatory drug.<br>References Delaney, E. J.; et al.: Steroids, 59, 196 (1994)<br></p>Formula:C21H27FO6Colore e forma:NeatPeso molecolare:394.43(5E)-Calcipotriene
CAS:<p>(5E)-Calcipotriene is a synthetic, natural, and analytical chemical. It is a white to off-white powder with a melting point of about 122 °C. (5E)-Calcipotriene has been used as an analytical standard for HPLC and as an impurity in the synthesis of calcitriol. The International Union of Pure and Applied Chemistry (IUPAC) name for this compound is 5Z,7Z,11Z,15Z-eicosapentaenoic acid. It can also be found in the form of 5Z,8Z,11Z,14E-eicosapentaenoic acid.</p>Formula:C27H40O3Purezza:Min. 95%Peso molecolare:412.6 g/molDexamethasone Impurity A
<p>Impurity A is an impurity of the drug product, dexamethasone. The impurity is a natural metabolite of dexamethasone that is found in the urine of patients taking this medication. Impurity A is chemically identified using HPLC and its purity verified using GC-MS and LC-MS. This impurity can be used as a reference standard for analytical purposes and as an impurity standard for pharmacopoeia testing.</p>Formula:C22H29FO5Purezza:Min. 95 Area-%Colore e forma:White Off-White PowderPeso molecolare:392.46 g/mol(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt
CAS:<p>(3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt is an impurity standard for the drug product. It is a synthetic metabolite that binds to proteins and has been found in human urine. The chemical synthesis of (3R,5S,6E)-7-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-3,5-dihydroxy-6 heptenoic acid sodium salt was performed using a high purity custom synthesis and high purity pharmacopoeia grade reagents.</p>Formula:C23H23FNNaO4Purezza:Min. 95%Peso molecolare:419.42 g/molCalcipotriol monohydrate
CAS:<p>Calcipotriol monohydrate, a Vitamin D3 analog, binds well to the vitamin D receptor, used in psoriasis research.</p>Formula:C27H42O4Purezza:99.95%Colore e forma:SolidPeso molecolare:430.62Desoximetasone impurity A
CAS:Prodotto controllato<p>Desoximetasone impurity A is an impurity found in the drug product Desoximetasone, which is a corticosteroid. It has been identified as an impurity in the drug product and there are no known uses of Desoximetasone impurity A. This impurity was determined to be natural based on its molecular weight, infrared spectrum, melting point, and elemental analysis. The molecular weight for Desoximetasone impurity A is 687.2 g/mol with a melting point at 89°C and an elemental analysis of Carbon: 29%, Hydrogen: 3%, Nitrogen: 16%, Oxygen: 32%.</p>Formula:C21H25FO4Purezza:Min. 95%Peso molecolare:360.42 g/molAtorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt
CAS:<p>Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt is a synthetic drug product that belongs to the class of statins. It has been used in research and development as a standard for HPLC analysis. The metabolite atorvastatin 3,5-dihydroxy-7-heptanoic acid (CAS No. 1105067-87-5) is also available from Sigma Aldrich. The impurity standards atorvastatin calcium salt and amorphous calcium sulfate are also available from Sigma Aldrich. Atorvastatin N-(3,5-dihydroxy-7-heptanoic acid)amide calcium salt is an API impurity in the synthesis of atorvastatin sodium (CAS No. 120781-93-1).</p>Formula:C40H48FN3O8CaPurezza:Min. 95%Peso molecolare:737.86 g/molAbiraterone dimer impurity
CAS:Prodotto controllato<p>Abiraterone dimer impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs. It is also a metabolite of abiraterone and has been detected in the urine of patients receiving the drug. Abiraterone dimer impurity is found in trace amounts in abiraterone acetate but its pharmacological significance is not known. This impurity has been detected in the urine of patients receiving abiraterone acetate therapy.</p>Formula:C43H57NO2Purezza:Min. 95%Peso molecolare:619.92 g/molFluticasone furoate EP impurity G
CAS:<p>Fluticasone furoate is a synthetic corticosteroid that has anti-inflammatory and immunosuppressive properties. It binds to the glucocorticoid receptor, which inhibits the production of inflammatory cytokines and mediators. The impurity standard used in this product is Fluticasone furoate EP impurity G. This impurity is a metabolite of fluticasone furoate with a molecular weight of 488. It has been shown that this impurity may have an effect on the pharmacokinetics of fluticasone furoate.</p>Formula:C27H29ClF2O6SPurezza:Min. 95%Peso molecolare:555.03 g/mol5,6-Dehydro-17beta-dutasteride
CAS:<p>5,6-Dehydro-17beta-dutasteride is a synthetic drug product that is used as an analytical standard for the determination of metabolites and impurities in pharmaceuticals. It also has been used as a natural metabolite, which can be found in human urine. 5,6-Dehydro-17beta-dutasteride is a metabolite of dutasteride, which is an antiandrogen medication for the treatment of benign prostatic hyperplasia (BPH). It is also known to inhibit the metabolism of other drugs such as ketoconazole and metoprolol.</p>Formula:C27H28F6N2O2Purezza:Min. 95%Peso molecolare:526.51 g/molBIBB 515
CAS:<p>BIBB 515 inhibits OSC, reducing cholesterol in hamsters by up to 25% with specific dosing.</p>Formula:C22H21ClN2O2Purezza:99.68%Colore e forma:SolidPeso molecolare:380.87rac 5-Keto Fluvastatin
CAS:<p>Rac5-Keto Fluvastatin is a synthetic, natural and custom synthesis drug product. It's CAS number is 1160169-39-0. Rac5-Keto Fluvastatin is a metabolite of fluvastatin. The racemic mixture has been prepared by the organic synthesis of racemic 5-keto fluvastatin, which was achieved by the use of a chiral auxiliary. Rac5-Keto Fluvastatin can be used in metabolism studies, as an analytical standard for HPLC, and as a reference material for pharmacopoeia.</p>Formula:C24H24FNO4Purezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:409.45 g/mol(betaR,deltaR)-2,3-Bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemicalcium salt
CAS:<p>(betaR,deltaR)-2,3-Bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemicalcium salt is an impurity that is used in the production of a drug product. This product is metabolized to (betaR,deltaR)-2,3-bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole 1 heptanoic acid which is used as an analytical standard for HPLC.</p>Formula:C66H66CaF4N4O10Purezza:Min. 95%Peso molecolare:1,193.34 g/molDutasteride EP impurity E
CAS:<p>Please enquire for more information about Dutasteride EP impurity E including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C27H30F6N2O2Purezza:Min. 95%Peso molecolare:528.54 g/molNorethindrone acetate impurity
CAS:<p>Norethindrone acetate impurity is a drug product that is used in the development and research of drugs. It is an analytical standard for norethindrone acetate, which is an impurity found in the synthesis of this drug. Norethindrone acetate impurity can be synthesized in different ways, such as natural or synthetic routes. It is also available as a custom synthesis or it can be purchased as an impurity standard. This compound's CAS number is 1175129-26-6 and it has a purity level of 99%.</p>Formula:C22H28O3Purezza:Min. 95%Colore e forma:PowderPeso molecolare:340.46 g/mol1,3-Bis-O-(tert-butyldimethylsilyl)-calcipotriene
CAS:<p>1,3-Bis-O-(tert-butyldimethylsilyl)-calcipotriene is a synthetic silyl ether of calcipotriene. It is used for the synthesis of drugs and as an impurity standard for HPLC analysis. 1,3-Bis-O-(tert-butyldimethylsilyl)-calcipotriene has been studied in metabolism studies and found to be natural, but it is not an API because it does not have a biological activity. It is also used in the development process of drugs and has been shown to be pharmacopoeia grade with a purity of at least 98%.</p>Formula:C39H68O3Si2Purezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:641.13 g/mol(24R)-Calcipotriene
CAS:<p>(24R)-Calcipotriene is a synthetic analog of calcitriol, the active form of vitamin D3. It is a proapoptotic agent that inhibits tumor growth by causing mitochondrial membrane potential collapse in cancer cells. (24R)-Calcipotriene has been shown to inhibit tumor growth in animals and human cells in vitro. This drug also potentiates the effects of other anticancer drugs such as doxorubicin and etoposide. In addition, it has been shown to have minimal toxicity at high doses in mice.</p>Formula:C27H40O3Purezza:Min. 95%Peso molecolare:412.6 g/molAtorvastatin 3-deoxyhept-2-enoic acid
CAS:<p>Atorvastatin is a potent inhibitor of the enzyme HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate. This inhibition reduces the production of cholesterol and other lipids in the liver. Metabolism studies have shown that atorvastatin undergoes extensive presystemic metabolism by cytochrome P450 enzymes, primarily CYP3A4 and CYP2C9. The drug is converted to inactive metabolites that are eliminated primarily through renal excretion. Atorvastatin has not been found to inhibit any of the following: cytochrome P450 1A1/2, 2C8/9, 2D6, 2E1, 3A4/5 or glucuronidases.</p>Formula:C33H33FN2O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:540.62 g/molFluticasone Impurity D
CAS:Fluticasone Impurity D is a sulfoxide that is found in the drug fluticasone. It is a conjugate of fatty acid and fatty alcohol, which are esters of irritants. Fluticasone Impurity D is an experimental model for inflammatory diseases. It can be used as a pharmaceutical dosage to enhance the effects of other drugs by increasing their absorption through the skin. The effects of this drug have been tested on tissues and experimental models, but not on humans.Purezza:Min. 95%Dexamethasone EP Impurity K
CAS:Prodotto controllatoDexamethasone EP Impurity K is an analytical standard for impurities in the drug product Dexamethasone EP. It is a synthetic methanolic solution of dexamethasone and a metabolite, which is chemically identical to the natural form. The purity of this impurity standard is 99.9%. This synthetic impurity is used for HPLC analysis as a pharmacopoeia-grade reference material.Formula:C22H26O4Purezza:Min. 95%Peso molecolare:354.44 g/molFluticasone furoate EP impurity E
CAS:<p>Fluticasone furoate EP impurity E is an analytical reference standard for pharmacopoeia and research. It is a synthetic fluticasone furoate EP impurity that has been custom synthesized for use as a high-purity, HPLC-grade standard. Fluticasone furoate EP impurity E is characterized by its natural origin and purity, making it appropriate for use in drug development and research. The CAS number for this product is 398454-97-2.</p>Formula:C25H31F3O5SPurezza:Min. 95%Peso molecolare:500.5 g/molFluorometholone impurity 5
CAS:<p>Fluorometholone impurity 5 is a drug product that has been custom synthesized. It has not yet been assigned to a CAS number. This compound exhibits high purity and is an analytical grade. Metabolism studies have been conducted on this substance, which is natural and can be found in the drug development phase. This impurity standard is for HPLC analysis and research and development purposes only.</p>Purezza:Min. 95%(3S,5R)-Atorvastatin calcium
CAS:<p>(3S,5R)-Atorvastatin calcium is an analytical standard for the drug atorvastatin. It has a purity of 99.9% and is manufactured in accordance with the requirements of the pharmacopoeia. The product is available as a white crystalline powder and is soluble in water, acetone, and ethanol. (3S,5R)-Atorvastatin calcium has been used in drug development and as an impurity standard for HPLC analysis. It also serves as a metabolite to characterize the production process of atorvastatin.</p>Formula:C66H68CaF2N4O10Purezza:Min. 95%Peso molecolare:1,155.34 g/molFluorometholone delta 9,11
CAS:Prodotto controllato<p>Fluorometholone delta 9,11 is a drug product that is used as an analytical reference standard for the quantitative determination of impurities in drugs. It is a natural metabolite and impurity in synthetic drugs such as fluoroquinolones and corticosteroids. Fluorometholone delta 9,11 has been shown to be a substrate for CYP3A4 and P-glycoprotein. This drug has also been shown to have anti-inflammatory effects and may decrease the risk of infection by suppressing neutrophil function.</p>Formula:C22H28O3Purezza:Min. 95%Peso molecolare:340.46 g/molAtorvastatinN-(3,5-dihydroxy-7-heptanoic acid)amide
CAS:Atorvastatin is a synthetic drug product. It is a prodrug that is converted to its active form, atorvastatin acid, in the body. Atorvastatin is used for lowering blood cholesterol levels in people with hypercholesterolemia and reducing the risk of coronary heart disease. This drug has been shown to reduce the number of deaths from coronary heart disease by 30% after five years of use. Atorvastatin also reduces the risk of stroke and fatal or non-fatal heart attack by 20%.Formula:C40H48FN3O8Purezza:Min. 95%Peso molecolare:717.82 g/molDexamethasone-17-ketone
CAS:Prodotto controllato<p>Please enquire for more information about Dexamethasone-17-ketone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C20H25FO3Purezza:Min. 95%Peso molecolare:332.42 g/molAY 9944
CAS:<p>AY 9944 inhibits DHCR7 enzyme (IC50=13 nM) and sterol isomerase, leading to hypocholesterolemia and 7DHC buildup.</p>Formula:C22H30Cl4N2Purezza:98.92% - 99.65%Colore e forma:SolidPeso molecolare:464.3Hexestrol diphosphate tetrasodium
CAS:Hexestrol diphosphate tetrasodium: synthetic ER agonist, may cause cancer, inhibits microtubule assembly, leads to mitotic arrest and DNA adducts.Formula:C18H24O8P2·xNaColore e forma:SolidPeso molecolare:518.26PF-02413873
CAS:PF-02413873 is a competitive antagonist of nonsteroidal progesterone receptor with a Ki of 2.6 nM.Formula:C18H21N3O3SPurezza:99.83% - 99.89%Colore e forma:SolidPeso molecolare:359.44Diethylstilbestrol dipropionate
CAS:Diethylstilbestrol dipropionate can be used in estrogen therapy of relapsed prostate cancer.Formula:C24H28O4Colore e forma:SolidPeso molecolare:380.48Cyproterone
CAS:<p>Cyproterone, an anti-androgen, treats female hirsutism and acne, and is used palliatively in prostate cancer.</p>Formula:C22H27ClO3Colore e forma:SolidPeso molecolare:374.97-Ketolithocholic acid
CAS:<p>7-Ketolithocholic acid absorbs and reduces endogenous bile acid and cholesterol secretion.</p>Formula:C24H38O4Purezza:98.68% - 99.9%Colore e forma:White - Almost White Solid PowderPeso molecolare:390.56Maxacalcitol
CAS:Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue.Formula:C26H42O4Purezza:≥98%Colore e forma:SolidPeso molecolare:418.61Zilpaterol
CAS:Zilpaterol is an acting ß-agonist that causes fat loss and muscle gain in cattle.Formula:C14H19N3O2Colore e forma:SolidPeso molecolare:261.32Isoflupredone
CAS:<p>Isoflupredone, a synthetic corticosteroid, inhibits inflammation and immune response in animals.</p>Formula:C21H27FO5Purezza:97.62% - 99.85%Colore e forma:SolidPeso molecolare:378.43Fludrocortisone
CAS:Fludrocortisone （Florinef） is a synthetic corticosteroid with moderate glucocorticoid potency and greater mineralocorticoid potency.Cost-effective and quality-assured.Formula:C21H29FO5Purezza:98.56% - 98.66%Colore e forma:White SolidPeso molecolare:380.45Promegestone
CAS:Promegestone is a progestin medication used in menopausal hormone therapy and in the treatment of gynecological disorders.Formula:C22H30O2Colore e forma:SolidPeso molecolare:326.47
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