Nucleosidi e Nucleotidi
I nucleosidi sono composti formati da una base azotata legata a uno zucchero (ribosio o desossiribosio). Quando un gruppo fosfato viene aggiunto al nucleoside, si forma un nucleotide. Questi composti sono fondamentali nella biologia cellulare, poiché i nucleotidi sono i mattoni essenziali del DNA e dell’RNA, responsabili dell’archiviazione e della trasmissione delle informazioni genetiche. I nucleosidi trovano applicazione nel trattamento delle malattie virali, agendo come inibitori della replicazione virale. I nucleotidi, oltre al loro ruolo strutturale negli acidi nucleici, sono coinvolti nei processi energetici, come la sintesi dell’ATP.
Presso CymitQuimica, offriamo un’ampia gamma di nucleosidi e nucleotidi essenziali per la ricerca in biologia molecolare, virologia e farmacologia.
Trovati 3431 prodotti di "Nucleosidi e Nucleotidi"
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5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine
CAS:Prodotto controllato<p>Impurity Capecitabine EP Impurity D<br>Applications 5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine (Capecitabine EP Impurity D) is a Capecitabine analog which shows antitumor activity.<br></p>Formula:C15H22FN3O6Colore e forma:NeatPeso molecolare:359.359-(2-Hydroxyethyl)guanine
CAS:Prodotto controllato<p>Impurity Aciclovir EP Impurity P<br>Applications 9-(2-Hydroxyethyl)guanine (Aciclovir EP Impurity P) is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.<br>References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);<br></p>Formula:C7H9N5O2Colore e forma:BeigePeso molecolare:195.18Folic Acid-13C5, 15N
CAS:<p>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Formula:C1413C5H19N615NO6Colore e forma:NeatPeso molecolare:447.351,2,4-Triazole-3-carboxylic Acid
CAS:<p>Impurity Ribavirin EP Impurity C<br>Applications 1,2,4-Triazole-3-carboxylic Acid (Ribavirin EP Impurity C) is a major metabolite of the antiviral agent Ribavirin (R414475).<br>References Miller, J.P. et al.: Ann. N.Y. Acad. Sci., 284, 211 (1977); Catlin, D. et al.: Ribavirin: Broad Spec. Antivir. Ag., 83 (1980); Lin, C.C. et al.: Antimicrob. Ag. Chemother., 50, 2368 (2006);<br></p>Formula:C3H3N3O2Colore e forma:White SolidPeso molecolare:113.07Canagliflozin Furanose Form (Mixture of Anomers)
CAS:Prodotto controllatoFormula:C24H25FO5SColore e forma:NeatPeso molecolare:444.52Adenosine 2',3'-Cyclic Phosphate-13C5 Triethylammonium Salt
CAS:Prodotto controllato<p>Applications A labelled 2',3'-cyclic nucleotide phosphodiester<br>References Voegtli, W., et al.: Biochemistry, 39, 15365 (2000), Bernstein, N., et al.: Mol. Cell, 17, 657 (2005), Blondal, T., et al.: J. Biol. Chem., 280, 5188 (2005), Shenoy, A., et al.: J. Mol. Biol., 365, 211 (2007),<br></p>Formula:C1113C5H27N6O6PColore e forma:NeatPeso molecolare:435.361-Methyl-4-nitro-5-thioimidazole
CAS:Prodotto controllatoFormula:C4H5N3O2SColore e forma:Yellow SolidPeso molecolare:159.17Acyclovir L-Leucinate
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Acyclovir L-Leucinate is an amino acid ester of the antiherpetic agent, Acyclovir (A192400). It is the Leucine analogue of Valacyclovir (V085000).<br>References Burnette, T. et al.: J. Biol. Chem., 270, 15827 (1995);<br></p>Formula:C14H23ClN6O4Colore e forma:NeatPeso molecolare:374.825-Methylcytidine
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 5-Methylcytidine is a derivative of Cytidine (C998300), found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.<br>References Kammerer, B., et al.: Anal. Biol. Chem., 382, 1017 (2005); Strong, L. and Matsunaga, H.: J. Surg. Oncol., 4, 528 (1972)<br></p>Formula:C10H15N3O5Colore e forma:NeatPeso molecolare:257.24Methyl 2,3-O-Isopropylidene-5-O-p-tolylsulfonyl-ß-D-ribofuranoside
CAS:Prodotto controllatoFormula:C16H22O7SColore e forma:NeatPeso molecolare:358.41Emtricitabine (1 mg/mL in Methanol)
CAS:Formula:C8H10FN3O3SColore e forma:ColourlessPeso molecolare:247.25N-(9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
CAS:Prodotto controllatoFormula:C11H15N5O5Colore e forma:NeatPeso molecolare:297.2673(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Triethylammonium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate.<br>References Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012); Lam, A.M., et al.: J. Virol., 85, 12334 (2011); Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010);<br></p>Formula:C28H61FN5O14P3Colore e forma:Off White SolidPeso molecolare:803.73D-Melphalan
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications D-Melphalan is an isomer of melphalan (M216900), which is an antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980),<br></p>Formula:C13H18Cl2N2O2Colore e forma:NeatPeso molecolare:305.22’,3’-Di-O-acetyl-5’-deoxy-5-fluoro-N4-(pentoxycarbonxyl)cytidine
CAS:Prodotto controllatoFormula:C19H26FN3O8Colore e forma:NeatPeso molecolare:443.423-(3-Azido-2,3-dideoxy-b-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
CAS:Prodotto controllato<p>Applications 3-(3-Azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione is an impurity of Zidovudine (A825000). Zidovudine is an antiviral agent used in the clinical treatment of HIV infections.<br>References Radatus, B.K., Org. Process. Res. Dev., 15, 1281 (2011)<br></p>Formula:C10H13N5O4Colore e forma:NeatPeso molecolare:267.242-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate 1-Methanesulfonate
CAS:Prodotto controllato<p>Applications Gemcitabine intermediate.<br>References Balzarini, J., et al.: Biochem. Pharmacol., 1988, 37, 2847 (1988), Hertel, L., et al.: Cancer Res., 50, 4417 (1990), Marquez, V., et al.: J. Med. Chem., 33, 978 (1990),<br></p>Formula:C20H18F2O8SColore e forma:Off-White To Light YellowPeso molecolare:456.41ent-Emtricitabine
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).<br>References Mellors, J., et al.: Science, 72, 1167 (1996), Reimann, K., et al.: J. Virol., 79, 8878 (2005), Rose, J., et al.: J. Biol. Chem., 280, 7413 (2005), Acierno, P., et al.: J. Immunol., 176, 5338 (2006),<br></p>Formula:C8H10FN3O3SColore e forma:NeatPeso molecolare:247.25(1R,2S,5R)-Menthol-5R-hydroxy-[1,3]-oxathiolane-2R-carboxylate
CAS:Prodotto controllatoFormula:C14H24O4SColore e forma:NeatPeso molecolare:288.409-[[2-Chloroprop-2-en-1-yl)oxy]methyl]guanine
CAS:Prodotto controllato<p>Impurity Ganciclovir EP Impurity A<br>Applications 9-[[2-chloroprop-2-en-1-yl)oxy]methyl]guanine (Ganciclovir EP Impurity A) is an impurity of Ganciclovir (G235000).<br></p>Formula:C9H10ClN5O2Colore e forma:NeatPeso molecolare:255.66
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