Sali e Derivati degli API
I sali degli Ingredienti Farmaceutici Attivi (API) sono composti formati dalla reazione di un acido con una base, risultando in un equilibrio ionico. Questi sali migliorano spesso la solubilità e la stabilità degli API, facilitandone l’assorbimento nel corpo. I derivati degli API sono varianti chimiche di un principio attivo che possono presentare proprietà migliorate o modificate per ottimizzare l’efficacia terapeutica. I sali di API sono utilizzati nella formulazione di farmaci orali, iniettabili e topici. Inoltre, i derivati degli API possono migliorare la farmacocinetica dei farmaci, ad esempio consentendo un rilascio controllato dei principi attivi.
Presso CymitQuimica, offriamo sali e derivati di API con la purezza e la qualità necessarie per la ricerca e lo sviluppo di formulazioni farmaceutiche.
Trovati 79464 prodotti di "Sali e Derivati degli API"
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Brinzolamide
CAS:Prodotto controllato<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Formula:C12H21N3O5S3Colore e forma:NeatPeso molecolare:383.51Repaglinide Acyl-β-D-glucuronide
CAS:<p>Applications A metabolite of Repaglinide (M7).<br></p>Formula:C33H44N2O10Colore e forma:NeatPeso molecolare:628.71Dihydro Cyclosporin A
CAS:Prodotto controllato<p>Applications A Cyclosporin A (C988900) analog, an immunosuppressant.<br>References Emmer, G., et al.: J. Med. Chem., 37, 1918 (1994), High, K., et al.: J. Biol. Chem., 269, 9105 (1994),<br></p>Formula:C62H113N11O12Colore e forma:WhitePeso molecolare:1204.63Riluzole-13C,15N2
CAS:Prodotto controllatoFormula:C713CH5F315N2OSColore e forma:Light Beige To Light YellowPeso molecolare:237.18Ref: ST-EA-CP-S3235
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT275
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-R10000
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-R48069
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaGeranylgeraniol (Natural)
CAS:Prodotto controllato<p>Stability Light Sensistive, Temperature Sensitive<br>Applications Geranylgeraniol, a precursor to Geranylgeranylpyrophosphate (G367600), is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-adsorption, inhibition of osteoclast formation, and kinase activation in vitro.<br>References Aiuchi, T., et al.: J. Biochem., 124, 300 (1998), Fisher, J.E., et al.: Proc. Natl. Acad. Sci. U.S.A. 96, 133 (1999), Montero, M.T., et al.: J. Immunol., 173, 4936 (2004), Campia, I., et al.: Br. J. Pharmacol., 158, 1777 (2009),<br></p>Formula:C20H34OColore e forma:NeatPeso molecolare:290.48Ref: ST-EA-CP-NIT002
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT154
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT142
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT057
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT190
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT032
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT107
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT070
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT094
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaDiclofenac-d4
CAS:Prodotto controllato<p>Applications Labelled Diclofenac is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004)<br></p>Formula:C142H4H7Cl2NO2Colore e forma:White To Light PinkPeso molecolare:300.17Ref: ST-EA-CP-NIT118
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT003
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaProbenecid
CAS:Prodotto controllato<p>Applications Uricosuric.<br>References McKinney, S.E., et al.: J. Pharmacol. Exp. Ther., 102, 208 (1951), Israili, Z.H., et al.: J. Med. Chem., 15, 709 (1972), Al-Badr, A.A., et al.: Anal. Profiles Drug Subs., 10, 639 (1981), Cunningham, R.F., et al.: Clin. Pharmacokinet., 6, 135 (1981),<br></p>Formula:C13H19NO4SColore e forma:WhitePeso molecolare:285.36Octenidine Dihydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Octenidine is an antiseptic (topical). Octenidine is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative.<br>References Slee, A.M., et al.: Antimicrob. Agents Chemother., 23, 531 (1983), Ghannoum, M.A., et al.: J. Antimicrob. Chemother., 25, 237 (1990), Allen, M., et al.: Microbiology, 152, 989 (2006), Ojha, A., et al.: Mol. Microbiol., 66, 468 (2007),<br></p>Formula:C36H62N4·2HClColore e forma:White To Off-WhitePeso molecolare:623.83Zephirol-d7
CAS:Prodotto controllato<p>Applications Labelled Zephirol. Quaternary ammonium composition to treat herpes, pseudomonas, staph, hepatitis and other infectious diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Berr, S., et al.: J. Phys. Chem., 91, 4760 (1987), Jones, M., et al.: Eur. J. Pharm. Biopharm., 48, 101 (1999), Okano, L., et al.: Langmuir, 16, 3119 (2000),<br></p>Formula:C21H31D7ClNColore e forma:NeatPeso molecolare:347.03Ref: ST-EA-CP-M28007
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaTolvaptan-d7
CAS:Prodotto controllato<p>Applications Labelled Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).<br>References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000), Udelson, J., et al.: Circulation, 104, 2417 (2001), Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005), Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006),<br></p>Formula:C26H18D7ClN2O3Colore e forma:NeatPeso molecolare:455.985-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is used as a reagent in the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclylmethyl)thiophene-2-carboxamide derivatives as antithrombotics. It is also used as a reagent in the synthesis of diamide derivatives as FXa inhibitors. 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is an intermediate for Edoxaban (E555520).<br>References Mochizuki, A., et al.: Jpn. Kokai Tokkyo Koho. JP 2010120852 A 20100603. Jun 3, 2010; Mochizuki, A., et al.: PCT Int. Appl. WO 2008123017 A1 20081016. Oct 16, 2008<br></p>Formula:C8H11ClN2O2SColore e forma:Light BrownPeso molecolare:234.7N-(R)-Glycidyl Phthalimide
CAS:Prodotto controllato<p>Applications Reagent used for the simultaneous preparation of amino alcohol solvating agents as well as preparation of orally available anticoagulants.<br>References Roehrig, S. et al: J. Med. Chem., 48, 5900 (2005); Bozkurt, S. et al: Tetra: Asymm., 22, 541 (2011);<br></p>Formula:C11H9NO3Colore e forma:NeatPeso molecolare:203.192-Chloro-N-phenylacetamide
CAS:Prodotto controllato<p>Applications 2-Chloro-N-phenylacetamide is used as a reagent in the synthesis of indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones which exhibit anticancer and antimicrobial activities in vitro.<br>References Gali, R., et al.: Bioorg. Med. Chem. Lett., 24, 4239 (2014)<br></p>Formula:C8H8ClNOColore e forma:NeatPeso molecolare:169.03Ref: ST-EA-CP-C31006
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta3’-Hydroxy Warfarin
CAS:Prodotto controllato<p>Applications A new metabolite of Warfarin using Cunninghamella elegans.<br>References Wong, Y. W., et al.: J. Pharma. Sci., 80, 305 (1991)<br></p>Formula:C19H16O5Colore e forma:NeatPeso molecolare:324.33Trimethylamine Monohydrochloride
CAS:Prodotto controllatoFormula:C3H9N·ClHColore e forma:NeatPeso molecolare:95.5712Diclofenac Acyl-β-D-glucuronide
CAS:Prodotto controllato<p>Applications A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.<br>References Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004)<br></p>Formula:C20H19Cl2NO8Colore e forma:NeatPeso molecolare:472.27cis-Nerolidol
CAS:Prodotto controllato<p>Applications cis-Nerolidol is one of the main component in the essential oils from fresh aerial parts of Thymus ciliatus (Lamiaceae). Also, it is a terpene that displays high potency on the contractility of cardiac muscle in guinea pig left atrium. A potential and effective treatment for malaria.<br>References Cherchar, H., et al.: Mor. J. Chem., 2, 85-89 (2014); Vasconcelos, C. M. L., et al.: Nat. Prod. Res., (2017); Saito, A. Y., et al.: Int. J. Antimicrob. Agents, 48, 641-646 (2016)<br></p>Formula:C15H26OColore e forma:ColourlessPeso molecolare:222.37Ref: ST-EA-CP-P219037
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaN-(4-(N-carbamoylsulfamoyl)phenethyl)-5-methylpyrazine-2-carboxamide
Formula:C15H17N5O4SPeso molecolare:363.39Ref: ST-EA-CP-G11044
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta5,6-trans Travoprost
CAS:<p>Applications An 5,6-trans isomeric impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600).<br></p>Formula:C26H35F3O6Colore e forma:NeatPeso molecolare:500.554,6-Dihydroxypyrazolo[3,4-d]pyrimidine-13C,15N2
CAS:Prodotto controllato<p>Applications A labelled metabolite of Allopurinol.<br>References Marro, P., et al.: Brain Res., 650, 9 (1994), Abramov, A., et al.: J. Neurosci., 27, 1129 (2007), Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007),<br></p>Formula:CC4H415N2N2O2Colore e forma:White To BeigePeso molecolare:155.09Decarbonyl Rivaroxaban
CAS:<p>Applications Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C18H20ClN3O4SColore e forma:White To Off-WhitePeso molecolare:409.8915-Keto Travoprost
CAS:Prodotto controllato<p>Stability Light Sensitive<br>Applications An impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600) used as an ocularly applied intraocular pressure reducing agent.<br></p>Formula:C26H33F3O6Colore e forma:NeatPeso molecolare:498.535-Hydroxy Diclofenac
CAS:<p>Applications A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kretz-Rommel, A., et al.: Toxicol. Appl. Pharmacol., 120, 155 (1993), Petronilli, V., et al.: J. Biol. Chem., 269, 16638 (1994), Bort, R., et al.: J. Pharmacol. Exp. Ther., 288, 65 (1998), Poon, G., et al.: Drug Metab. Dispos., 29, 1608 (2001),<br></p>Formula:C14H11Cl2NO3Colore e forma:Purple To Light RedPeso molecolare:312.152-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid
CAS:Prodotto controllato<p>Applications 2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid is an impurity of Febuxostat (F229000), an xanthine oxidase/xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout.<br>References Kadivar, M.H., et al.: J. Pharma. Biomed. Anal., 56, 749 (2011);<br></p>Formula:C16H18N2O4SColore e forma:White To Off-WhitePeso molecolare:334.39Keto Diclofenac Sodium Salt
CAS:<p>Applications Keto Diclofenac Sodium Salt is an impurity of Diclofenac (D436450), a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor.<br>References Sun, S., et al.: J. Liq. Chroma., 17, 433 (1994); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004); Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009);<br></p>Formula:C14H8Cl2NO3·NaColore e forma:NeatPeso molecolare:332.113-(Formylamino)-1H-pyrazole-4-carboxamide
CAS:Prodotto controllato<p>Impurity Allopurinol EP Impurity B / Allopurinol USP Related Compound B<br>Stability Hygroscopic<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxamide (Allopurinol EP Impurity B) is an impurity of Allopurinol (A547300) with inhibitory effects on human hypoxanthine phosphoribosyltransferase.<br>References Krenitzky, T.A. et al.: J. Biol. Chem., 244, 1263 (1969);<br></p>Formula:C5H6N4O2Colore e forma:White To Off-WhitePeso molecolare:154.127N-Nitroso Moexipril
CAS:Prodotto controllatoFormula:C27H33N3O8Colore e forma:Off-WhitePeso molecolare:527.572-(Cyanomethyl)indole
CAS:Prodotto controllato<p>Applications Intermediate in the preparation of carcinogenic indole derivatives.<br>References Kato, M., et al.: Chem. Pharm. Bull., 42, 2556 (1994),<br></p>Formula:C10H8N2Colore e forma:NeatPeso molecolare:156.183-Descyano Febuxostat
CAS:Prodotto controllato<p>Applications 3-Descyano Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.<br>References Kadivar, M.H., et. al.: J. Pharmaceut. Biomed. Anal., 56, 749 (2011); Vallu, V., et. al.: Anal. Chem. Indian J., 14, 339 (2014); Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C15H17NO3SColore e forma:NeatPeso molecolare:291.37N1-[2-(1-Piperazinyl)ethyl]-1,2-ethanediamine Hydrochloride
CAS:Prodotto controllatoFormula:C8H20N4•x(HCl)Colore e forma:NeatPeso molecolare:172.273646
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