Sali e Derivati degli API
I sali degli Ingredienti Farmaceutici Attivi (API) sono composti formati dalla reazione di un acido con una base, risultando in un equilibrio ionico. Questi sali migliorano spesso la solubilità e la stabilità degli API, facilitandone l’assorbimento nel corpo. I derivati degli API sono varianti chimiche di un principio attivo che possono presentare proprietà migliorate o modificate per ottimizzare l’efficacia terapeutica. I sali di API sono utilizzati nella formulazione di farmaci orali, iniettabili e topici. Inoltre, i derivati degli API possono migliorare la farmacocinetica dei farmaci, ad esempio consentendo un rilascio controllato dei principi attivi.
Presso CymitQuimica, offriamo sali e derivati di API con la purezza e la qualità necessarie per la ricerca e lo sviluppo di formulazioni farmaceutiche.
Trovati 79383 prodotti di "Sali e Derivati degli API"
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Ref: ST-EA-CP-NIT020
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-NIT145
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaZephirol-d7
CAS:Prodotto controllato<p>Applications Labelled Zephirol. Quaternary ammonium composition to treat herpes, pseudomonas, staph, hepatitis and other infectious diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Berr, S., et al.: J. Phys. Chem., 91, 4760 (1987), Jones, M., et al.: Eur. J. Pharm. Biopharm., 48, 101 (1999), Okano, L., et al.: Langmuir, 16, 3119 (2000),<br></p>Formula:C21H31D7ClNColore e forma:NeatPeso molecolare:347.03Ref: ST-EA-CP-M28007
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta3'-Hydroxy-4'-methoxydiclofenac
CAS:Prodotto controllato<p>Applications 3'-Hydroxy-4'-methoxydiclofenac is a derivative of Diclofenac (Sodium Salt: D436450). Diclofenac is the first non-steroidal anti-inflammatory drug (NSAID) that is derived from phenylacetic acid. Diclofenac, like other NSAIDs, primarily works by targeting the cyclo-oxygenase pathway in the arachidonic acid cascade, reducing the formation of inflammation mediators in the body.<br>References Ku, E., et al.: Am. J. Med., 80, 18 (1986); Simmons, D., et al.: Proc. Nat. Acad. Sci., 96, 3275 (1999); Small, R.: Clin. Pharm., 8, 545 (1989)<br></p>Formula:C15H13Cl2NO4Colore e forma:NeatPeso molecolare:342.17R-(+)-Warfarin-d5
CAS:Prodotto controllato<p>Applications R-(+)-Warfarin-d5 is the isotope labelled analog of R-(+)-Warfarin, an enantiomer of Warfarin (W498500). Coumarin anticoagulant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hagan, E.C., et al.: J. Am. Pharm. Assoc. Sci. Ed., 42, 379 (1953), Bell, R.G., et al.: Biochemistry, 11, 1959 (1972), Valente, J.E., et al.: J. Med. Chem., 20, 1489 (1977), Back, N., et al.: Pharmacol. Res. Commun., 10, 445, (1978), Babhair, S.A., et al.: Anal. Profiles Drug Subs., 14, 423 (1985), Takahashi, H., et al.: Echizen, Clin. Pharmacokinet., 40, 587 (2001),<br></p>Formula:C192H5H11O4Colore e forma:White To Off-WhitePeso molecolare:313.359Triethyl Phosphonoacetate
CAS:Prodotto controllato<p>Applications Reagent used for Horner-Emmons modification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hediger, M., et al.: Bioorg. Med. Chem., 12, 4995 (2004), Kim, J., et al.: Nat., 452, 239 (2008),<br></p>Formula:C8H17O5PColore e forma:ColourlessPeso molecolare:224.19Apixaban PG Ester-II
CAS:Prodotto controllato<p>Applications Apixaban PG Ester-II is one of the multiple constituents extracted from Biebersteinia multifida, that exhibits inhibitory activity on acetylcholinesterase.<br>References Xiang, F., et al.: Faming Zhuanli Shenqing (2019), CN 109432093 A 20190308.<br></p>Formula:C28H30N4O6Colore e forma:NeatPeso molecolare:518.56(R)-6-(4-Aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone
CAS:Prodotto controllato<p>Applications A metabolite of Levosimendan.<br>References Rubinstein, A., et al.: J. Pharmacol. Met., 19, 213 , (1988), Pollesello, P., et al.: J. Biol. Chem., 269, 28584 (1994), Yokoshiki, H., et al.: Eur. J. Pharmacol., 333, 249 (1997)<br></p>Formula:C11H13N3OColore e forma:NeatPeso molecolare:203.24Brinzolamide Hydrochloride
CAS:Prodotto controllato<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Formula:C12H21N3O5S3·ClHColore e forma:NeatPeso molecolare:419.977-Hydroxy Warfarin
CAS:Prodotto controllatoFormula:C19H16O5Colore e forma:Off WhitePeso molecolare:324.33Ref: ST-EA-CP-L10039
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaTicagrelor Amine Derivative
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Ticagrelor Amine Derivative is a metabolite of Ticagrelor (T437700). Ticagrelor is a reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Formula:C23H29F2N7O3SColore e forma:White To Off-WhitePeso molecolare:521.582-Chloro-N-phenylacetamide
CAS:Prodotto controllato<p>Applications 2-Chloro-N-phenylacetamide is used as a reagent in the synthesis of indolylmethylene benzo[h]thiazolo[2,3-b]quinazolinones which exhibit anticancer and antimicrobial activities in vitro.<br>References Gali, R., et al.: Bioorg. Med. Chem. Lett., 24, 4239 (2014)<br></p>Formula:C8H8ClNOColore e forma:NeatPeso molecolare:169.03Febuxostat 2-Butyl Isomer
CAS:Prodotto controllato<p>Applications Febuxostat 2-butyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)<br></p>Formula:C16H16N2O3SColore e forma:NeatPeso molecolare:316.37Ref: ST-EA-CP-A61009
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaLesinurad
CAS:Prodotto controllato<p>Applications Lesinurad is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.<br>References Burns, C., et al.: Lancet 377, 165 (2011); Miner, J. et al.: PCT Int. Appl. WO 2011159732 A1 20111222 (2011); Crittenden, D. B. et al.: Clinical Investigation 1, 1563-1575 (2011)<br></p>Formula:C17H14BrN3O2SColore e forma:NeatPeso molecolare:404.28Ref: ST-EA-CP-C23070
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestacis-Nerolidol
CAS:Prodotto controllato<p>Applications cis-Nerolidol is one of the main component in the essential oils from fresh aerial parts of Thymus ciliatus (Lamiaceae). Also, it is a terpene that displays high potency on the contractility of cardiac muscle in guinea pig left atrium. A potential and effective treatment for malaria.<br>References Cherchar, H., et al.: Mor. J. Chem., 2, 85-89 (2014); Vasconcelos, C. M. L., et al.: Nat. Prod. Res., (2017); Saito, A. Y., et al.: Int. J. Antimicrob. Agents, 48, 641-646 (2016)<br></p>Formula:C15H26OColore e forma:ColourlessPeso molecolare:222.37Levosimendan Triazene Impurity
CAS:<p>Stability Light Sensitive<br>Applications Levosimendan Triazene is an impurity of Levosimendan (L378000); a positive inotropic agent with vasodilating activity. Also cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995); Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996)<br></p>Formula:C22H23N7O2Colore e forma:NeatPeso molecolare:417.46Ref: ST-EA-CP-E52002
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-S18128
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-R36033
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-P219037
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-P168011
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-A85007
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-G29010
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-M69016
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-C22042
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: ST-EA-CP-N12017
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta(5E)-Bimatoprost
CAS:<p>Applications The trans-isomer used in the improved process for the production and purification of Bimatoprost (B386800).<br></p>Formula:C25H37NO4Colore e forma:NeatPeso molecolare:415.56Bispyrazolone
CAS:<p>Applications Bispyrazolone is an impurity of Edaravone (E335000).<br></p>Formula:C20H18N4O2Colore e forma:NeatPeso molecolare:346.383,4-Dihydro Ivermectin (Mixture of Diastereomers) (>90%)
CAS:Prodotto controllato<p>Impurity Ivermectin EP Impurity K<br>Applications 3,4-Dihydro Ivermectin is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. An invitro inhibitor of SARS-CoV-2/ Covid-19.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Campbell, W., et al.: Science, 221, 823 (1983); Glaziou, P., et al.: Trop. Med. Parasitol., 45, 253 (1994); Meinking, T., et al.: New Engl. J. Med., 333, 26 (1995); Caly, L., et al.: Antivir. Res., 178<br></p>Formula:C48H76O14Purezza:>90%Colore e forma:NeatPeso molecolare:877.114’-Hydroxy Diclofenac
CAS:Prodotto controllato<p>Stability Light Sensitive<br>Applications A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kretz-Rommel, A., et al.: Toxicol. Appl. Pharmacol., 120, 155 (1993), Petronilli, V., et al.: J. Biol. Chem., 269, 16638 (1994), Bort, R., et al.: J. Pharmacol. Exp. Ther., 288, 65 (1998), Poon, G., et al.: Drug Metab. Dispos., 29, 1608 (2001),<br></p>Formula:C14H11Cl2NO3Colore e forma:White To Light PurplePeso molecolare:312.15Perindoprilat
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Perindoprilat is an angiotensin-converting enzyme (ACE) inhibitor and antihypertensive.<br>References Pascard, C., et al.: J. Med. Chem., 34, 663 (1991)<br></p>Formula:C17H28N2O5Colore e forma:Off-WhitePeso molecolare:340.41Ivermectin B1a (>85%)
CAS:Prodotto controllato<p>Applications Ivermectin B1a is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178<br></p>Formula:C48H74O14Purezza:>85%Colore e forma:NeatPeso molecolare:875.09N-Despropyl-macitentan
CAS:Prodotto controllato<p>Applications N-Despropyl-macitentan, is an active metabolite which is part of a family of endothelin receptor antagonist that allows for treatment of pulmonary arterial hypertension (PAH)<br>References Atsmon, J., et al.: Clin. Pharmacokinet., 525, 685 (2013); Sidharta, P.N., et al.: Clin. Drug Invest. (2014)<br></p>Formula:C16H14Br2N6O4SColore e forma:NeatPeso molecolare:546.1915-Keto Bimatoprost
CAS:<p>Applications 15-Keto Bimatoprost is an impurity of Bimatoprost (B386800). Bimatoprost impurity III.<br>References Stjernschantz, J., et al.: Drugs Fut., 17, 691 (1992), Resul, B., et al.: J. Med. Chem., 36, 243 (1993),<br></p>Formula:C25H35NO4Colore e forma:NeatPeso molecolare:413.55rel-(1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-yl acetate
CAS:Prodotto controllato<p>Impurity Tiotropium EP impurity D<br>Applications (1R,3S,5S)-8-Methyl-8-azabicyclo[3,2,1]oct-6-en-yl-2-hydroxy-2,2-dithiophen-2-ylacetate is an impurity in the synthesis of Tiotropium Bromide (T444850), a muscarinic receptor antagonist. Bronchodilator.<br>References Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994); Donohue, J. F., et al.: Chest, 122, 47 (2002); Profita, M., et al.: Allergy, 60, 1361 (2005); Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006);<br></p>Formula:C18H19NO3S2Colore e forma:NeatPeso molecolare:361.48Ivermectin B1 Aglycon
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications Ivermectin B1 Aglycon is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. An invitro inhibitor of SARS-CoV-2/ Covid-19.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Campbell, W., et al.: Science, 221, 823 (1983); Glaziou, P., et al.: Trop. Med. Parasitol., 45, 253 (1994); Meinking, T., et al.: New Engl. J. Med., 333, 26 (1995); Caly, L., et al.: Antivir. Res., 178<br></p>Formula:C34H50O8Colore e forma:Off White PowderPeso molecolare:586.76N-Nitroso Moexipril
CAS:Prodotto controllatoFormula:C27H33N3O8Colore e forma:Off-WhitePeso molecolare:527.574-Chlorobenzal Chloride
CAS:<p>Applications 4-Chlorobenzal Chloride is an impurity that is formed in the synthesis of Benoxaprofen (B165300); a non-steroidal anti-inflammatory ophthalmic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cockerill, A.F., et al.: J. Chromatogr., 129, 339 (1976); Mathur, K., et al.: Bioorg. Med. Chem., 11, 1915 (2003); Zhao, M., et al.: Bioorg. Med. Chem., 15, 2815 (2007); Roy, K., et al.: Eur. J. Med. Chem., 44, 2913 (2009)<br></p>Formula:C7H5Cl3Colore e forma:NeatPeso molecolare:195.47Diclofenac Acyl-β-D-glucuronide Allyl Ester
CAS:Prodotto controllato<p>Applications An intermediate for the synthesis of Diclofenac’s glucuronide metaoblite.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kenny, J.R., et al.: J. Med. Chem., 47, 2816 (2004),<br></p>Formula:C23H23Cl2NO8Colore e forma:NeatPeso molecolare:512.34N-Carbamoyl Oxcarbazepine
Prodotto controllato<p>Applications N-Carbamoyl Oxcarbazepine is an impurity of Oxcarbazepine (O869250), a metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),<br></p>Formula:C16H13N3O3Colore e forma:NeatPeso molecolare:295.293-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one
CAS:Prodotto controllato<p>Applications 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one (cas# 545445-44-1) is a useful research chemical.<br></p>Formula:C20H25O3N3Colore e forma:BeigePeso molecolare:355.432-Amino-5-(trifluoromethoxy)phenyl Thiocyanate
CAS:<p>Applications An impurity of Riluzole (R510000).<br></p>Formula:C8H5F3N2OSColore e forma:NeatPeso molecolare:234.20Oxindole (2-Indolone)
CAS:Prodotto controllato<p>Applications Indole analogue; shows pharmacological activity.<br>References Mohammadi, M., et al.: Science, 276, 955 (1997), Bramson, H., et al.: J. Med. Chem., 44, 4339 (2001), Lane, M., et al.: Cancer Res., 61, 6170 (2001), Yu, B., et al.: Biochem. Pharmacol., 64, 1091 (2002),<br></p>Formula:C8H7NOColore e forma:Light RedPeso molecolare:133.15(5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone
CAS:Prodotto controllato<p>Applications (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.<br>References Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)<br></p>Formula:C30H42N2O3Colore e forma:NeatPeso molecolare:478.67N,N’-Bis[Des(5-chloro-2-carvoxythienyl) Rivaroxaban] Urea
CAS:Prodotto controllatoFormula:C29H32N6O9Colore e forma:WhitePeso molecolare:608.60
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