Sulfonamidi e Derivati
Le sulfonamidi sono composti che contengono un gruppo funzionale sulfonamidico (-SO₂NH₂), in cui un atomo di zolfo è legato a un gruppo amminico. Furono tra i primi antibiotici sintetici utilizzati in medicina, inibendo la sintesi dell’acido folico nei batteri, conferendo loro proprietà antimicrobiche. Sono utilizzate principalmente per trattare infezioni batteriche, sebbene il loro impiego sia diminuito a causa della resistenza antimicrobica. Oltre al loro uso come antibiotici, le sulfonamidi trovano applicazioni nel trattamento di malattie come la malaria e le malattie infiammatorie intestinali.
Presso CymitQuimica, offriamo sulfonamidi e i loro derivati ad alta purezza per la ricerca in microbiologia e lo sviluppo farmaceutico.
Trovati 2592 prodotti di "Sulfonamidi e Derivati"
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Indomethacin 1-Menthol ester
CAS:Prodotto controllato<p>Applications Indomethacin terpenoids' esters were synthesized and assessed both in vitro and in vivo as indomethacin dermal prodrugs.<br>References Bonina,, Francesco. , et al.: European Journal of Pharmaceutical Sciences, 14, 123 (2001),<br></p>Formula:C29H34ClNO4Colore e forma:NeatPeso molecolare:496.0385-Amino-3-(4-sulfonylphenyl)salicyclic Acid Sodium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 5-Amino-3-(4-sulfonylphenyl)salicyclic Acid Sodium Salt is an impurity of mesalamine (M258100), which is the active metabolite of Sulfasalazine (S699084). Anti-inflammatory (gastrointestinal).<br>References Friedman, G., et al.: Am. J. Gastroenterol., 81, 141 (1986); Tursi A., Expert Opin. Pharmacother., 6, 69 (2005);<br></p>Formula:C13H11NO6S•x(Na)Colore e forma:NeatPeso molecolare:309.29 + x(22.99)8-Propyl Etodolac
CAS:Prodotto controllato<p>Impurity Etodolac EP Impurity E<br>Applications 8-Propyl Etodolac (Etodolac EP Impurity E) is an impurity in the synthesis of Etodolac (E933100), may have use in the treatment of myeloma. COX-1/COX-2/β-catenin inhibitors.<br>References Humber, L.G., et al.: Med. Res. Rev., 7, 1 (1987); Balfour, J.A, et al.: Drugs, 42, 274 (1991); Kato, et al.: J. Pharm. Pharmacol., 53 1679 (2001);<br></p>Formula:C18H23NO3Colore e forma:NeatPeso molecolare:301.38trans-Carboxy Glimepiride-d5
CAS:Prodotto controllato<p>Applications An active labelled metabolite of Glimepiride (G410150).<br>References Groop, L., et al.: Diabetes Care, 15, 737 (1992), Muller, G., et al.: Diabetes, 42, 1852 (1993), Kramer, W., et al.: Biochem. Biophys. Acta, 119, 278 (1994),<br></p>Formula:C24H27D5N4O7SColore e forma:NeatPeso molecolare:525.63Gliclazide Impurity D
CAS:<p>Applications Gliclazide Impurity D is a manufacturing impurity of the drug Gliclazide (G409875) which is a sulfonylurea hypoglycemic agent and is used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972), Holmes, B., et al.: Drugs, 27, 301 (1984),<br></p>Formula:C15H20N2O3SColore e forma:NeatPeso molecolare:308.3959Ethyl 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide Carbamate
CAS:Prodotto controllatoFormula:C19H21ClN2O6SColore e forma:NeatPeso molecolare:440.90Methyl 5-Methoxy-2-methylindole-3-acetate
CAS:Prodotto controllato<p>Applications Intermediate in the preparation of Indomethacin<br>References Kalgutkar, A.S., et al.: Bioorg. Med. Chem., 13, 6810 (2005),<br></p>Formula:C13H15NO3Colore e forma:NeatPeso molecolare:233.26(S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Dioxide
CAS:Prodotto controllato<p>Applications (S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Dioxide has been used as a reactant for the preparation of Brinzolamide (AL-4862) [B677600], a topical carbonic anhydrase inhibitor.<br>References Conrow, R.E., et. al.: Org. Process Res. Dev., 3, 114 (1999)<br></p>Formula:C10H16N2O6S3Colore e forma:NeatPeso molecolare:356.44Hydroxy Gliclazide
CAS:Prodotto controllato<p>Applications The major hydroxylated metabolite of Gliclazide (G409875).<br>References Miyazaki, H., et al.: Eur. J. Drug Metab. Pharmacokinet., 8, 117 (1983), Rieutord, A., et al.: Xenobiotica, 25, 1345 (1995),<br></p>Formula:C15H21N3O4SColore e forma:NeatPeso molecolare:339.41Mefenamic Acyl-β-D-glucuronide
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Mefenamic acid metabolite.<br>References Besunder, J., et al.: Clin. Pharmacokinet., 14, 261 (1988), Smith, P., et al.: Drug Metab. Dipos., 18, 639 (1990), Kraus, D., et al.: Clin. Pharmacol. Ther., 54, 351 (1993), Sato, J., et al.: Biol. Pharm. Bull., 16, 811 (1993),<br></p>Formula:C21H23NO8Colore e forma:NeatPeso molecolare:417.412-Nitrophenyl Phenyl Sulfide
CAS:Prodotto controllato<p>Applications 2-Nitrophenyl Phenyl Sulfide is used in the study of non-nucleoside reverse transcriptase inhibitors of HIV-1.<br>References Chan, J., et al.: J. Med. Chem., 44, 1866 (2001); McMahon, J., et al.: Antimicro. Agents Chemother., 37, 754 (1993)<br></p>Formula:C12H9NO2SColore e forma:NeatPeso molecolare:231.273-Methoxy Acetaminophen-d3
CAS:Prodotto controllato<p>Applications 3-Methoxy Acetaminophen-d3 is deuterium labeled 3-Methoxy Acetaminophen (M226050). 3-Methoxy Acetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C92H3H8NO3Colore e forma:NeatPeso molecolare:184.207bis(4-Nitrophenyl) Sulfone
CAS:Prodotto controllato<p>Applications BIS(4-NITROPHENYL) SULFONE (cas# 1156-50-9) is a useful research chemical.<br></p>Formula:C12H8N2O6SColore e forma:NeatPeso molecolare:308.262'-Phenoxymethanesulfonanilide
CAS:Prodotto controllatoFormula:C13H13NO3SColore e forma:White To Off-WhitePeso molecolare:263.314-Carboxy Tolbutamide-d9
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A labelled metabolite of Tolbutamide. Formed by the cytochrome CYP2CIIC8 and IIC9 subfamily of P450 enzymes.<br>References Relling, etl al.: J. Pharmacol. Exp. Ther., 252, 442 (1990), Parent, et al.: J. Pharmacol. Exp. Ther., 261, 780 (1992), Ho, et al.: Life Sci., 52, 21 (1993),<br></p>Formula:C12D9H7N2O5SColore e forma:NeatPeso molecolare:309.39N-Desethyl-N-(2-boronoethyl) Dorzolamide Hydrochloride
Formula:C10H17BN2O6S3•(HCl)Colore e forma:NeatPeso molecolare:368.2636462-Chloro-5-(1-ethoxy-3-oxoisoindolin-1-yl)benzenesulfonamide
CAS:Prodotto controllato<p>Applications Ethyl Chlorthalidone is an impurity of Chlorthalidone (C427500). Chlorthalidone is used as a diuretic; an antihypertensive.<br>References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966), Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972), Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985),<br></p>Formula:C16H15ClN2O4SColore e forma:Off WhitePeso molecolare:366.82N-Acetyl Dapsone-d8 (Major)
CAS:Prodotto controllato<p>Applications A labelled metabolite of Dapsone (D193250).A representative lot is 73% d8, 23% d7 and 3% d6 with no d0.<br>References Shin, I., et al.: J. App. Pharmacol., 10, 193 (2002), Bhaiya, P., et al.: Toxicol. App. Pharmacol., 215, 158 (2006), Paixao, P., et al.: Eur. J. Pharm. Sci., 36, 544 (2009),<br></p>Formula:C14H6D8N2O3SColore e forma:NeatPeso molecolare:298.396-Methylpyrazinecarboxylic Acid
CAS:Prodotto controllato<p>Applications 6-Methylpyrazinecarboxylic Acid can be used to synthesize compounds that are active against M.tuberculosis H37Rv. Similarly, it can be used to synthesize compounds that are useful for the inhibition, prevention or therapy of tumor cell invasion, metastasis, inflammation, hepatitis, or liver dysfunction.<br>References Vontor, T., et al.: Cesk. Farm., 34, 441 (1985); Oka, K., et al.: Jpn. Kokai Tokkyo Koho, JP 2007210926 A 20070823 (2007)<br></p>Formula:C6H6N2O2Colore e forma:NeatPeso molecolare:138.12
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![(S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-Diox…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH946200.webp&w=3840&q=75)
