Sulfonamidi e Derivati
Le sulfonamidi sono composti che contengono un gruppo funzionale sulfonamidico (-SO₂NH₂), in cui un atomo di zolfo è legato a un gruppo amminico. Furono tra i primi antibiotici sintetici utilizzati in medicina, inibendo la sintesi dell’acido folico nei batteri, conferendo loro proprietà antimicrobiche. Sono utilizzate principalmente per trattare infezioni batteriche, sebbene il loro impiego sia diminuito a causa della resistenza antimicrobica. Oltre al loro uso come antibiotici, le sulfonamidi trovano applicazioni nel trattamento di malattie come la malaria e le malattie infiammatorie intestinali.
Presso CymitQuimica, offriamo sulfonamidi e i loro derivati ad alta purezza per la ricerca in microbiologia e lo sviluppo farmaceutico.
Trovati 2592 prodotti di "Sulfonamidi e Derivati"
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rac Indapamide-d3
CAS:Prodotto controllato<p>Applications Labelled Indapamide. Used as an antihypertensive. Diuretic.<br>References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),<br></p>Formula:C16H13D3ClN3O3SColore e forma:White To Light Orange ColorPeso molecolare:368.858-Methylquinoline
CAS:<p>Applications 8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.<br>References Smith, C. J., et al.: Mutat. Res., Fund. Mol. Mech. Mut., 379, 167 (1997)<br></p>Formula:C10H9NColore e forma:Light Yellow LiquidPeso molecolare:143.1854’-Hydroxyacetophenone Oxime
CAS:Prodotto controllato<p>Impurity Paracetamol EP Impurity G<br>Applications 4’-Hydroxyacetophenone Oxime is an impurity of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) Sengupta, S., et al.: Metal. Based Drugs, 8, 293 (2002) (2) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(3) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974)<br></p>Formula:C8H9NO2Colore e forma:NeatPeso molecolare:151.16Gliclazide-d4
CAS:Prodotto controllatoFormula:C152H4H17N3O3SColore e forma:White To Off-WhitePeso molecolare:327.44Tosylurethane
CAS:Prodotto controllato<p>Impurity Gliclazide EP Impurity C<br>Applications Tosylurethane (Gliclazide EP Impurity C) is an intermediate in the synthesis of Gliclazide (G409877), a sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972); Holmes, B., et al.: Drugs, 27, 301 (1984)<br></p>Formula:C10H13NO4SColore e forma:Off WhitePeso molecolare:243.284-Amino-6-chloro-1,3-benzenedisulfonamide
CAS:Prodotto controllato<p>Impurity Hydrochlorothiazide EP Impurity B<br>Applications Diuretic. Hydrochlorothiazide EP Impurity B.<br>References Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Joshi, S., et al.: J. Pharm. Biomed. Anal., 52, 362 (2010), Castillo-Garit, J., et al.: Eur. J. Pharm. Sci., 39, 30 (2010),<br></p>Formula:C6H8ClN3O4S2Colore e forma:White To Light BrownPeso molecolare:285.73Sulfacetamide-d4
CAS:Prodotto controllato<p>Applications Sulfacetamide-d4 is the isotope labelled analog of Sulfacetamide. Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties<br>References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);<br></p>Formula:C8H6D4N2O3SColore e forma:NeatPeso molecolare:218.27Acetaminophen-13C2, 15N1
CAS:Prodotto controllato<p>Applications Acetaminophen-13C2, 15N1 is doubly labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C613C2H915NO2Colore e forma:WhitePeso molecolare:154.14Sulfamethoxazole β-D-Glucuronide
CAS:<p>Applications The main metabolite of Sulfamethoxazole.<br>References Altenburger, R., et al.: Environ. Toxicol. Chem., 19, 2341 (2000), Pascoe, R., et al.: Anal. Chem., 73, 6014 (2001), Zhaohua, H., et al.: Eur. J. Med. Chem., 36, 863 (2001),<br></p>Formula:C16H19N3O9SColore e forma:NeatPeso molecolare:429.40p-Butyl Ibuprofen (~90%)
CAS:Prodotto controllatoFormula:C13H18O2Purezza:~90%Colore e forma:NeatPeso molecolare:206.28Ibuprofen Piconol
CAS:Prodotto controllato<p>Applications Ibuprofen Piconol is an anti-inflammatory agent that can be synthesized from Ibuprofen (I140000), which is a selective cyclooxygenase inhibitor.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); Xiang, L., et al.: Huaxi Yaoxue Zazhi, 21, 178 (2006); Chem. and Eng. News p9, July 4 (2016);<br></p>Formula:C19H23NO2Colore e forma:NeatPeso molecolare:297.394'-Isobutylacetophenone
CAS:Prodotto controllato<p>Impurity Ibuprofen EP Impurity E<br>Applications 4'-Isobutylacetophenone (Ibuprofen EP Impurity E) is a degradation product of Ibuprofen in tablets, which is a known toxin. Ibuprofen (I140000) impuritiy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reynolds, D., et al.: Pharm. Technol., 26, 48 (2002), Wasylaschuk, W., et al.: J. Pharm. Sci., 96, 106 (2007),<br></p>Formula:C12H16OColore e forma:Colourless To Light YellowPeso molecolare:176.25rac Indapamide
CAS:<p>Applications Used as an antihypertensive. Diuretic.<br>References Leary, et al.: Curr. Ther. Res., 15, 571 (1973), Kyncl, J., et al.: Arzneim.-Forsch., 25, 1491 (1975), DiFeo, T.J., et al.: Anal. Profiles Drug Subs. Excip., 23, 229 (1994),<br></p>Formula:C16H16ClN3O3SColore e forma:White To Off-WhitePeso molecolare:365.833-[4-(2-Pyridylsulfamoyl)phenyl] Sulfasalazine
CAS:Prodotto controllato<p>Applications An impurity of Sulfasalazine (S699084).<br></p>Formula:C29H22N6O7S2Colore e forma:NeatPeso molecolare:630.65rac Ibuprofen
CAS:Prodotto controllato<p>Applications A selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Ibuprofen has has been shown to reduce Ebola infection in rodents (4).This compound is a contaminant of emerging concern (CECs).<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998); (4) Chem. and Eng. News p9, July 4 (2016);<br></p>Formula:C13H18O2Colore e forma:NeatPeso molecolare:206.28Ethyl 2-Bromoisovalerate
CAS:<p>Applications Ethyl 2-Bromoisovalerate (cas# 609-12-1) is a compound useful in organic synthesis.<br></p>Formula:C7H13BrO2Colore e forma:NeatPeso molecolare:209.08Indomethacin-d4
CAS:Prodotto controllato<p>Applications Nonsteroidal anti-inflammatory agent (NSAID).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Formula:C192H4H12ClNO4Colore e forma:White To Off-WhitePeso molecolare:361.81Brinzolamide
CAS:Prodotto controllato<p>Applications Carbonic anhydrase inhibitor. Antiglaucoma agent.<br>References Silver, L.H., et al.: Am. J. Ophthalmol., 126, 400 (1998), Davies, N., et al.: Clin. Exp. Pharmacol. Physiol., 27, 558 (2000), Stave, J., et al.: Ophthalmologe, 99, 276 (2002),<br></p>Formula:C12H21N3O5S3Colore e forma:NeatPeso molecolare:383.51N-Hydroxy Sulfamethoxazole
CAS:Prodotto controllato<p>Applications A Sulfamethoxazole metabolite.<br>References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),<br></p>Formula:C10H11N3O4SColore e forma:NeatPeso molecolare:269.282-(4-Chloro-3-sulfobenzoyl)-benzoic Acid
CAS:Prodotto controllato<p>Applications 2-(4-Chloro-3-sulfobenzoyl)-benzoic Acid is an impurity of Chlorthalidone (C427500) which is used as a diuretic.<br>References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966); Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972); Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985)<br></p>Formula:C14H9ClO6SColore e forma:NeatPeso molecolare:340.74Phthalide
CAS:Prodotto controllato<p>Applications Phthalide may be used in scaffolds for the design of high potency monoamine oxidase (MAO) inhibitors.<br>References Li, P.Z., et. al.: Med. Chem. Res., 23, 3624 (2014)<br></p>Formula:C8H6O2Colore e forma:ColourlessPeso molecolare:134.13(R)-(-)-Ibuprofen
CAS:Prodotto controllato<p>Applications A nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C13H18O2Colore e forma:White SolidPeso molecolare:206.282,4-Dichloro-5-sulfamoylbenzoic Acid
CAS:Prodotto controllato<p>Impurity Furosemide EP Impurity B<br>Applications 2,4-Dichloro-5-sulfamoylbenzoic Acid is a chlorinated sulfamoylbenzoic acid with diuretic acid.<br>References Shani, J. et al.: Pharmacology, 26, 172 (1983); Lebedev, A.A. et al.: Khim.-Farm. Zhur., 19, 1205 (1985);<br></p>Formula:C7H5Cl2NO4SColore e forma:WhitePeso molecolare:270.09Hydroflumethiazide
CAS:Prodotto controllato<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Formula:C8H8F3N3O4S2Colore e forma:NeatPeso molecolare:331.29Methiocarb Sulfone
CAS:<p>Applications Methiocarb Sulfone is a pesticide which is used in the protection of crops from insects and fungus.<br>References Wong, J. et al.: J. Agri,. Food. Chem., 58, 5897 (2010); Ghini, S. et al.: Arch. Env. Cont. Toxicol., 47, 479 (2004);<br></p>Formula:C11H15NO4SColore e forma:Colourless SolidPeso molecolare:257.31Furosemide-d5
CAS:Prodotto controllato<p>Applications Labelled Furosemide (F865000). Furosemide inhibits ion co-transport in the kidney. Furosemide is used as a diuretic.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Benet, L.Z.: J. Pharmacokinet. Biopharm., 7, 1 (1979)<br></p>Formula:C12D5H6ClN2O5SColore e forma:WhitePeso molecolare:335.77Tetraethyleneglycol Bisibuprofen Ester
CAS:<p>Applications Tetraethyleneglycol Bisibuprofen Ester is an impurity of ibuprofen (rac, I140000) which is a selective cyclooxygenase inhibitor. It inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Formula:C34H50O7Colore e forma:Colourless To Light BrownPeso molecolare:570.7573-Chloro-2-methylaniline
CAS:Formula:C7H8ClNColore e forma:Light Yellow To Light BrownPeso molecolare:141.60Ibuprofen Sodium Salt Dihydrate
CAS:Prodotto controllatoFormula:C13H17O2·2H2O·NaColore e forma:NeatPeso molecolare:264.293N-Acetyl Zonisamide
CAS:Prodotto controllato<p>Applications A metabolite of Zonisamide (Z700000), a new anticonvulsant.<br>References Perchalski, R. J., et al.: J. Clin. Pharmacol., 26, 435 (1986), Stiff, D.D., et al.: Drug Metab. Disp., 18, 888 (1990),<br></p>Formula:C10H10N2O4SColore e forma:NeatPeso molecolare:254.26(R)-(-)-Ibuprofen-d3
CAS:Prodotto controllato<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C13H15D3O2Colore e forma:NeatPeso molecolare:209.3N-(p-Toluenesulfonyl)urea
CAS:<p>Applications N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide (G598350), a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.<br>References Hellman, B., et al.: Metabol. Clinc. Experiment., 23, 839 (1974); Tozuka, Z., et al.: J. Pharma. Sci., 100, 4024 (2011);<br></p>Formula:C8H10N2O3SColore e forma:NeatPeso molecolare:214.242α-(4-Isobutylphenyl)ethanol
CAS:<p>Applications The photodegradation product of Ibuprofen (I140000). Shows cytotoxicity activity.<br>References Kobayashi, S., et al.: Biochemistry, 23, 4589 (1984), Karthein, R., et al.: Eur. J. Biochem., 171, 313 (1988), Maranon, M., et al.: Phytochem., 37, 1217 (1994),<br></p>Formula:C12H18OColore e forma:Colourless LiquidPeso molecolare:178.27Trimethoprim-13C3
CAS:Prodotto controllato<p>Applications Antibacterial.<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Formula:C3C11H18N4O3Colore e forma:NeatPeso molecolare:293.30N-Methylsulfonyl Nimesulide
CAS:<p>Impurity Nimesulide EP Impurity F<br>Applications N-Methylsulfonyl Nimesulide is an impurity of Nimesulide (N477500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kulkarni, S., et al.: Curr. Sci., 83, 1442 (2002), Nguyen, D., et al.: J. Sep. Sci., 29, 1836 (2006), Zacharis, C., et al.: J. Pharm. Biomed. Anal., 49, 726 (2009),<br></p>Formula:C14H14N2O7S2Colore e forma:NeatPeso molecolare:386.40Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers)
CAS:<p>Stability Hygroscopic, Not stable in aqueous solutions.<br>Applications Ibuprofen Acyl-β-D-glucuronide (mixture of diastereomers) (cas# 115075-59-7) is a compound useful in organic synthesis.<br></p>Formula:C19H26O8Colore e forma:NeatPeso molecolare:382.408-Desethyl Etodolac
CAS:Prodotto controllato<p>Impurity Etodolac EP Impurity A<br>Applications 8-Desethyl Etodolac (Etodolac EP Impurity A) is an impurity of Etodolac (E933100) which was examined for mutagenicity in reverse mutation tests on bacteria. Etodolac impurity A.<br>References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),<br></p>Formula:C15H17NO3Colore e forma:NeatPeso molecolare:259.30Glipizide
CAS:Prodotto controllato<p>Applications A sulfonylurea hypoglycemic agent. Used as an antidiabetic.<br>References Ambrogi, et al.: Arzneimittel-Forsch., 21, 200 (1971), Fuccella, et al.: J. Clin. Pharmacol., 13, 68 (1973), Brogden, R.N., et al.: Drugs, 18, 329 (1979), Lebovitz, H.E., et al.: Pharmacother., 5, 63 (1985)<br></p>Formula:C21H27N5O4SColore e forma:WhitePeso molecolare:445.54Metazachlor
CAS:Prodotto controllato<p>Applications A chloroacetanilide herbicide used on vegetable crops.<br>References Matthies, M., et al.: Environ. Sci. Technol., 43, 9223 (2009); Hollender, J., et al.: Environ. Sci. Technol., 43, 7862 (2009); Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010); Liu, B., et al.: J. Agric. Food Chem., 58, 2673 (2010);<br></p>Formula:C14H16ClN3OColore e forma:Off White To Light BeigePeso molecolare:277.752-Aminopyrimidine
CAS:<p>Applications 2-Aminopyrimidine is used in the synthesis of sulfonamides as isoform-selective inhibitors with efficacy in rodent pain models.<br>References Focken, T. et al.: ACS Med. Chem., 7, 277 (2016); Reddy, M. et al.: Bioorg. Med. Chem., 24, 521 (2016);<br></p>Formula:C4H5N3Colore e forma:NeatPeso molecolare:95.10N-Acetyl Sulfamethoxazole-d4 (major)
CAS:Prodotto controllatoFormula:C122H4H9N3O4SColore e forma:Light Orange Light BrownPeso molecolare:299.34Diethyl Carbonate
CAS:Prodotto controllato<p>Applications Diethyl Ester Carbonic Acid is used in the synthesis of 2-oxooxazolidines as antibacterials. Also used in the synthesis of donepezil/huperzine fragments as acetylcholinesterase inhbitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gregory, W. et al.: J. Med. Chem., 32, 1673 (1989); Bioorg. Med. Chem., 21, 676 (2013);<br></p>Formula:C5H10O3Colore e forma:Colourless To Light YellowPeso molecolare:118.034-(2-Methylpropyl)benzeneethanol
CAS:Prodotto controllatoFormula:C12H18OColore e forma:NeatPeso molecolare:178.27Triclocarban-d4 (4-chlorophenyl-d4)
CAS:Prodotto controllato<p>Applications Triclocarban-d4 (4-chlorophenyl-d4) (CAS# 1219799-29-7) is a useful isotopically labeled research compound.<br></p>Formula:C132H4H5Cl3N2OColore e forma:Off-WhitePeso molecolare:319.614-Acetylamino-2-chlorophenol
CAS:Prodotto controllato<p>Impurity Paracetamol EP Impurity C/ Acetaminophen impurity C<br>Applications 4-Acetylamino-2-chlorophenol is an impuirty of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formula:C8H8ClNO2Colore e forma:White To Light PurplePeso molecolare:185.61O-Desmethyl Indomethacin
CAS:Prodotto controllato<p>Applications The major metabolite of Indomethacin.<br>References Lewis, R., et al.: J. Clin. Invest., 53, 1607 (1974), Alvan, G., et al.: Clin. Pharmacol. Ther., 18, 364 (1975), Mungall, D., et al.: J. Pharm. Sci., 73, 1000 (1984), Baldwin, S., et al.: Xenobiotica, 25, 261 (1995),<br></p>Formula:C18H14ClNO4Colore e forma:NeatPeso molecolare:343.76
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