Monosaccaridi

Remdesivir impurity

Fucose 2-nitrophenylhydrazone is a custom synthesis that is a modification of fucose. It has been used in methylation, click modification, and fluorination. This compound has been shown to be effective in the synthesis of oligosaccharides and polysaccharides. Fucose 2-nitrophenylhydrazone has also been used as an intermediate for the synthesis of saccharides such as monosaccharide and sugar.

(R)-Ketoprofen b-D-glucuronide is a synthetic modified sugar that is produced by the glucuronidation of ketoprofen, a nonsteroidal anti-inflammatory drug. The modification of ketoprofen with glucuronic acid can be achieved through an enzymatic process, which is catalyzed by UDP-glucuronyltransferase. This modification increases the solubility of ketoprofen and its ability to penetrate cells. (R)-Ketoprofen b-D-glucuronide has been shown to have antibacterial properties against Gram positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. It has also shown antiviral activity against HIV-1 due to its inhibition of reverse transcriptase, which is an enzyme important for viral replication.

N-Acetyl-L-neuraminic acid is a glycosylation compound that is an important component of the cell wall of Gram negative bacteria. It is used in the synthesis of polysaccharides and in the formation of complex carbohydrates. N-Acetyl-L-neuraminic acid has been studied for its potential use as a drug delivery agent due to its ability to inhibit the activity of enzymes such as α-mannosidase, which can lead to tumor metastasis. This compound can be synthesized using methylation, fluorination, and click chemistry, or custom synthesized by ordering specific monosaccharides. N-Acetyl-L-neuraminic acid can also be modified with acetate groups to create an acetylated form for use in chemical analysis or as a substrate for enzymatic reactions.

1,2,3,4-Tetra-O-acetyl-D-fucopyranose is a glycosylation agent that can be used in the synthesis of complex carbohydrates or in the modification of natural polysaccharides. It can be fluorinated to produce 1,2,3,4-tetra-O-fluoro-D-fucopyranose or modified with a click reagent to produce 1,2,3,4-tetra-[5-(N'-diethylamino)pentyl]-D-fucopyranose. The CAS number for this product is 109712-63-7. This product is available for custom synthesis and is sold at a purity of >99%.

Clofibric acid acyl-b-D-glucuronide is a reactive chemical species that has been shown to have genotoxic effects. It binds to DNA and forms covalent adducts, leading to mutations in the DNA sequence. Clofibric acid acyl-b-D-glucuronide is a metabolite of clofibrate, which is used for the treatment of hyperlipidemia and atherosclerosis. This metabolite can be detected in human blood, serum, and liver samples by GC/MS, with a limit of detection of 0.1 ng/mL (0.0003 µg/L).

D-Arabinose-5-13C is a fluorinated monosaccharide that has been used in the synthesis of oligosaccharides and polysaccharides. It can be custom synthesized to meet customer specifications. D-Arabinose-5-13C is a white, crystalline powder that is soluble in water. This compound can be methylated or glycosylated for further modification.

PBS 57 is a pluripotent cell-derived protein that has been shown to be a potent vaccine adjuvant. PBS 57 is derived from the plasma of pregnant women and contains the following antigenic determinants: glucose, human albumin, and human immunoglobulin G. PBS 57 can stimulate both humoral and cellular immunity in mice with deficiencies in antibody production or T cells. PBS 57 has also been shown to have strong pro-inflammatory cytokine activity, which may be due to its ability to induce galacturonic acid release from macrophages.

Mannioside A is a postulated antigen that may be found in the Dracaena genus of plants. This compound has been shown to have an affinity for membranes, which could possibly be used as a strategy for vaccines and other pharmaceutical products. Mannioside A also has hemolytic activity, which may be useful in developing new treatments for autoimmune disorders such as multiple sclerosis.

6-O-Trityl-D-glucose is a sugar derivative that is synthesized by reacting 6,6'-dichloro-1,1'-binaphthyl with D-glucose. It has been used as a model for the stereospecific hydrolysis of polystyrene catalyzed by lipase. The reactive carbonyl group in the molecule allows for substitution reactions to occur at the hydroxyl groups and yields are dependent on the substituent effects.

N-Acetyl-D-[UL-13C6]glucosamine is a complex carbohydrate that contains a sugar at the end of a glycosidic bond. This product is modified with methylation, glycosylation, and fluorination. It has CAS No. 127959-06-2, High purity, and is custom synthesized for your specific needs.

4'-Hydroxytrazodone b-D-glucuronide is a modification of the drug 4'-hydroxytrazodone, which is used to treat hypertension and depression. The modification prevents the degradation of 4'-hydroxytrazodone by glucuronyl transferase enzymes in the liver, prolonging its half-life. It is synthesized from the glycogen or starch of plants such as corn, wheat, or potatoes. This compound can also be found in natural sources such as honey and fruit juices.