Peptidi

<p>Neuromedin-U-23 is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-SQNPVQPIGPQTPK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-RRRRRRRRRC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Cancer/testis antigen 1 (92-100) is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>[Leu3]-Oxytocin is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-DLPAPIER-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DKPTYFE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-EKL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>MiniAP-4 peptide is a short nontoxic derivative of apamin (a neurotoxin from bee venom) used as a blood-brain barrier (BBB) shuttle peptide.</p>

<p>Peptide H-VMAPRSLLL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-LQEYTQTILR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-QYNVTQAFGR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-TGLQEVEVK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-IYTWIEDHF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>MUC1(126-149)-Tn (140) is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-MESSAKRKMDPDNPD-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-GNDIAFHFNPR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>SynB1 is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-KSTGKANKITITNDKGRLSK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SSTGPGEQLR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-CSRNLIDCGGGDGGCSRNLIDC-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>H-GKQGGKAR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Chlorotoxin is a neurotoxic peptide that belongs to the class of macrocyclic lactones. It was originally isolated from the venom of the deathstalker scorpion, Leiurus quinquestriatus, which is found in North Africa. Chlorotoxin has potent immunosuppressive and cytotoxic effects that are mediated by its ability to bind to ion channels in cell membranes through disulfide bonds. This peptide induces apoptosis and inhibits tumor growth in mice by targeting cancer cells and inducing cell death. The chlorotoxin molecule is conjugated with a variety of molecules to increase its stability and bioavailability for delivery into cells.</p>

<p>H-WKWWPGIF-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-SLLTQPSPA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-KSDSC-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Parathyroid hormone (PTH) is a peptide hormone that regulates the concentration of calcium, phosphorus and vitamin D in the blood. It is synthesized by the parathyroid glands and acts on bone, kidney and intestine to regulate the level of these substances in the blood. PTH has an N-terminal 34 amino acid residue that is responsible for the biological activity of the hormone. Inhibitors of PTH are used as research tools to study receptor interactions and ion channels.</p>

<p>GsMTx4 is a ryanodine receptor agonist that binds to the ryanodine receptor and activates signal pathways. It has been shown to activate mechanosensitive channels and regulate intracellular Ca2+ levels by inducing an increase in Ca2+ release from the endoplasmic reticulum. GsMTx4 has also been shown to have pharmacological effects on cells, as well as physiological effects on Grammostola spatulata, such as inhibition of locomotion and increased mortality. GsMTx4 has also been shown to have antiviral properties against infectious diseases such as influenza, herpes simplex virus-1, and West Nile virus.</p>

<p>Neuropeptide:<br>Neuropeptides are small signaling molecules produced and released by neurons engaged in many physiological functions. Indeed, neuropeptides act on neural substrates such as G protein-coupled receptors (GPCRs), tyrosine-kinase receptor, insuline-like peptides and also ion channels. Actions of neuropeptides result in slow-onset, long-lasting modulation of synaptic transmission.<br>Neuropeptide NPSF (SQAFLFQPQRF-NH2):<br>Neuropeptide NPSF (SQAFLFQPQRF-NH2) is part of the FMRFamide-related peptides family. Neuropeptide NPSF has shown an important role in pain regulation and plays a role of anti-opiate. Moreover, Neuropeptide NPSF seems to be implicate in variety of physiological processes such as food intake, insulin release, blood pressure regulation and electrolyte balance. Neuropeptide NPSF (SQAFLFQPQRF-NH2) is useful in opioid research.</p>

<p>Hi-5 is a recombinant, human protein that inhibits the high mobility group box 1 (HMGB1), an inflammatory mediator. HMGB1 is produced by activated macrophages and triggers inflammation reactions in response to tissue injury or infection. Hi-5 can be used as a pharmacological tool for the study of HMGB1-mediated inflammation and as a research tool for the discovery of new drugs that target HMGB1.<br>Hi-5 has been shown to inhibit the interaction between HMGB1 and its receptors, which may be due to its ability to bind to both ligands and receptors of HMGB1.</p>

<p>Helospectin I is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-YLDEIPPKF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-EHYG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>A Cholesterol Ester Transfer Protein (CETP) light tryptic peptide standard responsible for use in protein identification and quantitation studies. CETP is an enzyme which moves cholesterol esters from high density lipoproteins (HDL) to apolioprotein B-containing particles. This action lowers the amount of HDL which may increase the risk of the disease atherosclerosis.</p>

<p>APETx2 is a drug that inhibits the activity of apetx2, a protein which is involved in the regulation of ion channels and endothelin-A receptors. APETx2 has been shown to inhibit the activity of channels involved in pain perception and may have therapeutic potential as a pressor agent. This drug has also been shown to have anti-inflammatory properties, which are likely due to its inhibition of EGF receptor activity. The mechanism of action for this drug remains unclear, but it may work by blocking the channel or receptor for EGF.</p>

<p>This Haptoglobin Heavy Tryptic Peptide Standard has the potential for use in proteomics studies and in the identification and quantitation of proteins. Haptoglobin is involved in the removal of free hemoglobin and also in neutralizing oxidative damage.Peptide sequence: H-VTSIQDWVQK^-OH</p>

<p>HBsAg is the surface antigen of the Hepatitis-B-Virus (HBV) S-gene. The capsid of a virus has different surface proteins from the rest of the virus. The antigen is a protein that binds specifically on one of these surface proteins.</p>

<p>ATP Synthase Subunit O, Mitochondrial is a recombinant protein that belongs to the ATP synthase subunit family. It has been shown to be an activator of ion channels and receptor. The protein is also able to facilitate the interactions between proteins and ligands. ATP Synthase Subunit O, Mitochondrial has a molecular weight of approximately 44 kDa and an isoelectric point of 9.6. This product can be used as research tool for cell biology, pharmacology, and biochemistry studies.</p>

<p>Human IgG3 (hinge) heavy tryptic peptide standard for use in protein identification and quantitation studies. Human IgG3 is one of the four subclasses of IgG and it induces complement-mediated cellular lysis. Its hinge region is extended and is made up of 62 amino acids.</p>

<p>Parathyroid Hormone (1-84) N15 Labeled, human, recombinant is a peptide that is used as a research tool in the field of cell biology and pharmacology. It has been shown to inhibit the activity of ion channels and act as an activator for several receptor types. This product is highly purified and can be used in various applications. The CAS number is 51401-06-6.</p>

<p>HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, and H2AFN are histone proteins that are components of the nucleosome. They are involved in regulating gene expression. Histones can be analyzed by a proteomics technique known as TrypTides to identify modifications to the protein's amino acid sequence. The Proteomics Tools Kit provides a number of tools for performing peptide enrichment and analysis of proteins extracted from cells or tissues. In this kit is an MS Calibrator-2 (25nmol) which is used to calibrate mass spectrometers with different capabilities.</p>

<p>Borrelia Burgdorferi Basic Membrane Protein A (BBMPA) is a protein that belongs to the Borrelia burgdorferi bacterium. It is a glycoprotein found on the surface of the bacterial cell, which has been shown to be involved in adhesion to host tissue. BBMPA is composed of two identical subunits, each containing five domains. These domains are involved in different functions and range from binding to other proteins and lipids to receptor-binding sites for host cells. This protein has been studied extensively as it is important for pathogenicity and infectivity of Borrelia Burgdorferi.</p>

<p>Cecropin A is an antimicrobial peptide active against Gram-positive and Gram-negative bacteria.<br>Some studies have suggested that cecropin A binds to negatively charged membrane lipids and form a packed layer which permeabilize the membranes and help to kill bacteria. It was shown that cecropin A presents a LC50 of 0.9 µM and a LC90 of 1.7 µM against certain E.Coli strains.<br>Besides its well-known antimicrobial properties, studies have demonstrated tumoricidal activity of cecropin A against leukemia, lymphoma, colon carcinoma cell lines and other tumour cell lines.<br>Furthermore, Cecropin A has a fungicidal activity. A study has shown that cecropin A reaches a complete lethality at approximately 25 mM for germinating conidia of Aspergillus spp. and a complete lethality for nongerminated and germinated conidia of Fusarium spp. at 1.5 mM.</p>

<p>High quality, quantitated heavy/light peptide calibrator for actin beta in Mass Spectroscopy research. Actin beta is an actin isoform and is one of two non-muscle cytoskeletal actins. Actins play roles in cell integrity, structure and motility.</p>

<p>For Protein Identification and Quantitation</p>

<p>This is a recombinant human Leukocyte-Associated Ig-Like Receptor 2 (LAIR2) protein. It is an activator of the LAIR2 receptor, which is a member of the immunoglobulin superfamily. LAIR2 is expressed on activated T cells and NK cells. This protein also can interact with other receptors, such as CD4 and FcRγ, to inhibit ion channels and activate cell signaling pathways. LAIR2 has been shown to be involved in immune responses, including antibody production and cytokine release by activated lymphocytes.</p>

<p>For Protein Identification and Quantitation</p>

<p>Modified H-2kb tetramer peptide for further modification (e.g. addition of N-term tag)</p>

<p>An Alpha-2-Macroglobulin light tryptic peptide standard for protein identification and quantitation studies. Alpha-2-Macroglobulin is a broad spectrum protease inhibitor which also plays roles in cell migration and in the binding of growth factors and cytokines.</p>

<p>Peptide H-NVEDLSGGELQR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Portion of Influenza NP</p>

<p>Cyclin-Dependent Kinase Inhibitor 2A (CDK2A) is a cyclin-dependent kinase inhibitor that inhibits the activity of cyclin-dependent kinases. CDK2A is a protein that belongs to the family of cyclin-dependent kinase inhibitors. It inhibits the activity of various cyclin-dependent kinases and prevents cell growth by suppressing protein synthesis. CDK2A is expressed in many human tissues, including erythrocytes, brain, heart, lung, muscle, pancreas, spleen, and testis. Cyclin-Dependent Kinase Inhibitor 2A can be used as an anti-cancer agent due to its ability to inhibit tumor proliferation.</p>

<p>The Tripartite Motif Containing 21 protein (TRIM21) is a human recombinant that is expressed in E. coli. TRIM21 is a glycosylated polypeptide chain, which has been shown to interact with the HIV-1 Vpu protein. TRIM21 binds to the HIV-1 Vpu protein and prevents it from interacting with the CD4 molecule on T cells, thereby inhibiting viral replication. TRIM21 also has been shown to be involved in the regulation of mRNA stability and translation by binding to polyribosomes and preventing ribosomal translocation.</p>

<p>NH2-dPEG®4-Glu(OH)-NH-dPEG®4-Glu(OH)-NH-m-dPEG®24 is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

<p>As a member of the tachykinin neuropeptide family, Neurokinin B is involved in the dilation of blood vessels, the contraction of smooth muscles and the excitation of neurons. This product can be applied as a NK3 receptors selective agonist.</p>

<p>Oxytocin is a peptide hormone and neurotransmitter. It is primarily used in the brain to regulate social behavior, such as maternal behaviour, sexual arousal and romantic attachment. Oxytocin is also used for uterine contractions during childbirth and to induce labour. Oxytocin can be administered by injection or as nasal spray. It has a half-life of about two minutes in the blood stream and its effects last up to one hour. Oxytocin is a nonapeptide with the amino acid sequence: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-Leu-Met-(OH). The oxytocin receptor (OXTR) belongs to G protein coupled receptors (GPCR), which are known for their roles in cell signaling, oncogenesis, immunity, inflammation, pain sensation and endocrine regulation. The OXTR is expressed throughout the body including the uterus and vagina.</p>

<p>GLP-1 (Human, Rat, Mouse)-EIA Kit is a ready-to-use kit that contains a recombinant human GLP-1 peptide. This kit is designed for the quantitative measurement of GLP-1 in human serum or plasma by ELISA. It uses a polyclonal antibody to detect the protein and has no cross-reactivity with other pancreatic hormones. The assay can be used with rat and mouse samples as well.</p>

<p>TGF-β is a cytokine with two forms, TGF-β1 and TGF-β2. The tgf-beta protein is a molecule that controls cell growth, differentiation and apoptosis. It can be found in the desiccated state, which must be reconstituted before use. Reconstitution of the protein requires acetonitrile and trifluoroacetic acid. Cytokines are molecules that regulate cell behavior by acting on other cells. Chromatographic techniques are used to separate these molecules by size and charge, while growth factors are molecules that promote cell growth and differentiation. The experimentally determined molecular mass of TGF-β1 is 25 kDa.END&gt;</p>

<p>NHS-m-dPEG® (MW = 685) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-m-dPEG® (MW = 685) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Hepatitis E virus (HEV) is a virus that infects the liver and causes hepatitis. Recombinant HEV ORF2 protein was produced by recombinant techniques in Escherichia coli. The recombinant HEV ORF2 protein has been shown to be immunogenic in mice, rabbits, and humans. Immunodominant epitopes were found at amino acid positions 448-456 and 468-480.</p>

<p>Please enquire for more information about [Gln18]-Platelet Factor 4 (15-22) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>C-Peptide (Mouse)-EIA Kit is a mouse C-peptide EIA kit. It is designed for the quantitative measurement of C peptide in serum samples from mice. The kit contains an antibody that recognizes mouse C peptide, and a conjugate that binds to the antibody. The kit also contains a biotin-labeled anti-mouse IgG antibody, which reacts with the conjugate to form a complex that is subsequently detected by an enzyme-conjugated streptavidin. The amount of complex formed is proportional to the amount of C peptide present in the sample.</p>

<p>Anti-Substance P Serum is a high purity protein that specifically binds to the receptor for substance P, which is a peptide hormone. This product has an affinity for the high affinity binding site of the receptor and inhibits the activity of substance P. Anti-Substance P Serum is used as a research tool in pharmacology and cell biology, as well as in antibody production.</p>

<p>BIM 23056 is a type of drug that binds to the receptor and inhibits its activity. BIM 23056 has been shown to have anticancer effects in vitro and in vivo. It is a membrane-permeable substance, which means it can pass through the cell membrane and into the cell where it blocks the function of certain receptors. This drug also has a physiological effect on mammalian tissue, including fibroblasts, as well as on other cells that are sensitive to growth factors.</p>

<p>Please enquire for more information about Pneumadin (rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Omega-conotoxins are a group of peptides found in the venom of predatory marine snails. Omega-conotoxin MVIIC is a potent inhibitor of nicotinic acetylcholine receptors. It blocks the activation and desensitization of nicotinic acetylcholine receptor channels and has been used as a research tool to study the function of these proteins. Omega-conotoxin MVIIC binds to its target by interacting with specific sites on the alpha subunit of nicotinic acetylcholine receptor channels, which leads to inhibition of voltage-gated calcium channels. The high purity and low endotoxin levels make this product suitable for life science research applications.</p>

<p>Anti ACTH (1-23) (Rat) Serum is a recombinant peptide that is an activator of the hypothalamus. It has been shown to have a high affinity for the receptor, and it can be used as a research tool in cell biology and pharmacology. Anti ACTH (1-23) (Rat) Serum is used in the study of ion channels, ligands, and antibodies. This peptide has been used to inhibit the release of ACTH from the pituitary gland and can be used to study the effects of anti-ACTH on other hormones. Anti ACTH (1-23) (Rat) Serum is purified from E. coli cells with a CAS number of 58612-37-8.</p>

<p>Bromoacetamido-dPEG®24-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromoacetamido-dPEG®24-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Nucleoside Diphosphate Kinase E.coli (recombinant) is a research peptide that belongs to the group of protein kinases. It is used in scientific studies and experiments to investigate various cellular processes and signaling pathways. This recombinant protein kinase has been shown to play a crucial role in the phosphorylation of nucleoside diphosphates, which are important molecules involved in energy metabolism and cell signaling. By catalyzing the transfer of phosphate groups, Nucleoside Diphosphate Kinase E.coli regulates the balance of nucleotide triphosphates, which are essential for DNA replication, RNA synthesis, and protein synthesis. Its unique properties make it an invaluable tool for researchers studying cellular mechanisms and developing new therapeutic strategies.</p>

<p>Peptide H-WYIWLGFIAGLIAIV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>CCK-33 is a peptide that belongs to the family of CCK peptides. It is an inhibitor of the CAS protein, which is involved in cell growth and differentiation. CCK-33 has been shown to inhibit the activation of cells by binding to the receptor sites on the cell membrane. CCK-33 also binds to receptors that are involved in ion channels, such as NMDA receptors and alpha adrenergic receptors. This can be used as a research tool for studying protein interactions and receptor sites. The antibody forms of CCK-33 are widely used in research laboratories because they can be used to block or activate specific proteins or receptors on cells.</p>

<p>Boc-Glu(OBzl)-Gly-Arg-AMC is a peptide that can be used as a research tool. It has been shown to bind to the nicotinic acetylcholine receptor, which is found in the central and peripheral nervous systems. Boc-Glu(OBzl)-Gly-Arg-AMC has also been shown to inhibit ion channels, such as the voltage gated potassium channel.</p>

<p>Pyr-Gly-Arg-AMC is a peptide that can be used as a research tool to study the interactions between proteins in the cell. Pyr-Gly-Arg-AMC binds to the receptor site of ion channels and inhibits their function. The high purity of this product means that it is suitable for use in research.</p>

<p>APP669-711, also known as Amyloid Precursor Protein (APP) 669-711 or Aβ−3–40, may have a potential use as a biomarker for Alzheimer's disease.</p>

<p>Lipid A is a bacterial endotoxin that activates macrophages and dendritic cells, which in turn activate T-cells. It is a ligand for the CD14 receptor, which is a pattern recognition molecule found on macrophages and dendritic cells. Lipid A also binds to the Toll-like receptor 4 (TLR4) on host cells, initiating an inflammatory response. Lipid A has been used as a research tool to study cell biology related to activation of macrophages and dendritic cells leading to cytokine production. This activator has also been used as a ligand in antibody studies, ion channel studies, protein interactions, pharmacology experiments with peptides, and life science research.</p>

<p>Please enquire for more information about 6-[D10]Leu-Glargine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Anti Nociceptin / Orphanin FQ (Human, Rat) Serum is a peptide that belongs to the family of orphanin FQ peptides. It has been shown to activate ion channels and ligand-gated channels. Anti Nociceptin / Orphanin FQ (Human, Rat) Serum is a high purity, pharmacology research tool for use in cell biology and receptor studies.</p>

<p>SPAI-1 is a protein that is found in the cytosol and nucleus of cells. It belongs to the family of inhibitor proteins, which regulate the activity of other proteins. SPAI-1 inhibits the activity of many different types of protein kinases. Inhibitors such as SPAI-1 are often used as research tools for studying protein interactions, activators, ligands, and receptors. This antibody can be used as a reagent to detect and locate SPAI-1 in cells or tissues by immunohistochemistry.</p>

<p>Secretin (Porcine) Antiserum is a research tool that is used to activate the secretin receptor. Secretin is an inhibitor of ion channels, which may be due to its ability to bind to the secretin receptor and inhibit its activity. The purified protein has a high purity and can be used in antibody experiments, cell biology, or pharmacology.</p>

<p>Alpha-1-Acid Glycoprotein light tryptic peptide standard for protein identification and quantitation. Alpha-1-Acid Glycoprotein is an acute phase protein whose concentration in serum increases during, infection, inflammation and tissue injury.</p>

<p>Neurotensin is a neuropeptide that is involved in the regulation of a variety of physiological functions, including neurotransmission, cardiovascular function, and appetite. It is composed of 13 amino acids and is primarily produced in the gastrointestinal tract and the central nervous system.<br>Neurotensin acts as a neurotransmitter and neuromodulator in the brain, where it is synthesized by neurons in several regions, including the hypothalamus, amygdala, and nucleus accumbens. In addition to its role in neurotransmission, neurotensin has been shown to be involved in the regulation of food intake and energy metabolism. It is thought to promote satiety and reduce food intake by interacting with the hypothalamus and other brain regions involved in appetite regulation.<br>Neurotensin has also been studied for its potential therapeutic applications as it has been shown to be associated with the pathophysiology of conditions such as Parkinson's disease, pain, schizophrenia, cancer and inflammatory bowel disease.</p>

<p>Anti Galanin (Porcine) Serum is a research tool that is used to activate, bind, and inhibit the ligand-receptor interactions. It is also used for the study of ion channels and cell biology. Anti Galanin (Porcine) Serum can be used as an antibody or as a peptide in pharmacology studies. The protein interactions are used in life science research, as well as for inhibitor studies.</p>

<p>[D-Ala2,Met5]-Enkephalin is an inhibitory neurotransmitter that binds to receptors in the brain and spinal cord. It affects physiological functions such as locomotion, pain sensation, and blood pressure. Enkephalins are analogs of the natural neurotransmitter enkephalin that are synthesized by enzymatic cleavage of the latter from a larger precursor molecule called proenkephalin. [D-Ala2,Met5]-Enkephalin has been shown to be an effective antinociceptive agent when administered intraperitoneally or intravenously in rats. It also acts as a pressor agent and produces dextran sulfate-induced nociception in mice. The pharmacological properties of enkephalins have been shown using various analytical methods including acid analysis.</p>

<p>Insulin is a peptide hormone that regulates glucose levels in the blood. It is produced by beta cells in the pancreas and released when blood sugar levels rise. Insulin lowers blood sugar levels, but it also has other functions, such as protein synthesis and cell growth. Insulin stimulates receptors on cells to take up glucose from the bloodstream. Inhibitors of insulin are used for type 1 diabetes mellitus treatment and research purposes. Insulin can be used to study ion channels, antibody production, and receptor binding.</p>

<p>FGF21 is a protein that in humans is encoded by the FGF21 gene. It is a member of the fibroblast growth factor (FGF) family and was originally identified as an anti-diabetic hormone that regulates glucose homeostasis. FGF21 also has roles in lipid metabolism and regulation of energy homeostasis, such as through its interactions with PPARs, RXRs, LXRs, and other nuclear receptors. The receptor for FGF21 is FGFR1c and it acts as a high-affinity agonist of this receptor. The ligand for FGFR1c is FGF19.</p>

<p>TentaGel B resins represent a line of bifunctional resins that are useful for orthogonal synthesis. TentaGel; is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol) as shown below. The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. Particle size 90 µm; capacity: 02-03 meq/g<br>Inside: NH2 Outside: Boc</p>

<p>The most potent microbicide of the mouse Paneth cell α-defensins and is degraded by MMP-7. This product has disulfide bonds between Cys4-Cys30, Cys15-Cys37, and Cys19-Cys39, is available in the Hydrochloride salt form and as a 0.1mg vial.</p>

<p>m-dPEG®48-OH is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, m-dPEG®48-OH is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.</p>

<p>FRET-25Asp is a peptide that can be used in research as an activator, antibody, and inhibitor. It is used as a tool to study protein interactions with the cell membrane and ion channels. FRET-25Asp has also been shown to inhibit the activity of some receptors and ligands.</p>

<p>An aza-dibenzocyclooctyne (DBCO) product used for strain-promoted azide-alkyne cycloaddition.  The amine terminus of the molecule reacts with carboxylic acids and their active esters to form stable amide bonds. Insoluble in water, DBCO-amine is slightly soluble to sparingly soluble in most organic solvents.</p>

<p>TentaGel resin; constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol). The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix.<br>TentaGel; HL (High Load) (mean particle size 75 µm: capacity 04-06 meq/g).<br>Substitution Functional Group:-O-CH2-CH2-OH</p>

<p>dPEG®4-Lys(t-Boc)-NH-m-dPEG®24 is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.</p>

<p>Cystatin SN is a cysteine protease inhibitor that is involved in the regulation of protein catabolism and inflammation. Cystatins are natural inhibitors of cystein proteases, which are involved in the degradation of proteins. Cystatin-S can inhibit the activity of various cysteine proteases, including cathepsin B, cathepsin L, and papain. The recombinant human form of Cystatin SN has been shown to inhibit various ion channels such as calcium channels and potassium channels. It also inhibits the activation of other molecules by binding to them. This inhibition may be due to its ability to bind with receptors on cells or its ability to bind with ligands.</p>

<p>D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin is a peptide that is an antagonist of bradykinin. It has been shown to bind to bradykinin receptors and inhibit the effects of bradykinin in both the vascular system and central nervous system. D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin may be used to treat diseases such as asthma or chronic obstructive pulmonary disease (COPD).</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Originally identified in Heloderma horridum horridum (Mexican beaded lizard), exendin-3 is in the glucagon family. Exendin 3 stimulates vasoactive intestinal peptide (VIP) receptors in high concentrations. This leads to increased cAMP levels and amylase secretion in the pancreas. However, low exendin-3 exposure only increases cAMP levels. In applications, exendin-3 was found to induce hypotension by relaxation of cardiac, smooth muscle. Using a tag, exendin-3 is being investigated as a stable agonist for GLP1R to detect insulinomas, a pancreatic B cell-derived cancer with high GLP1R expression. Exendin 3 has also been used on mouse models to assess its effect on glucose-stimulated insulin secretion in glucagon receptor knockout (Gcgr-/-) backgrounds. Understanding the interplay between exendin 3 and metabolism could provide new insights into the obesity crisis.</p>

<p>Boc-Gly-Arg-Arg-AMC is a research tool that has a high purity and is used in cell biology, antibody production, ion channels, and protein interactions. It is an inhibitor of ion channels, which can be used for pharmacology to study the function of ion channels. Boc-Gly-Arg-Arg-AMC has also been shown to inhibit binding between the ligand and receptor.</p>

<p>Bombesin is a small peptide that was first isolated from the skin of a frog, Bombina bombina, with homologs later found to be present in mammalian tissues, including the brain and gastrointestinal tract. It is a member of the bombesin-like peptide family, which includes several related peptides such as gastrin-releasing peptide (GRP) and neuromedin B.<br>Bombesin acts as a neuromodulator and regulates various physiological functions, including gastrointestinal motility and stimulation of gastrin release from G cells. It also plays a role in the regulation of cardiovascular function and neurotransmitter release. In addition, bombesin has been shown to stimulate the growth and proliferation of certain types of cancer cells, including prostate and lung cancer cells, through its interaction with bombesin receptors. It may therefore be used as a potential biomarker for certain cancers.<br>This product is available as a 0.5mg vial.</p>

<p>Phe-Met-MCA is a peptide that specifically activates the ATP-sensitive potassium (KATP) channels. These channels are important for regulating cellular energy metabolism and membrane potential. Phe-Met-MCA is an inhibitor of protein kinase C (PKC), which regulates the activity of KATP channels by phosphorylation. The peptide is also an inhibitor of other protein kinases, including PKCζ, PKCε, and PKCθ.</p>

<p>Amyloid beta-Protein (Human, 1-40) (Scrambled) is a peptide that consists of 40 amino acids. It is a fragment of the amyloid precursor protein. Amyloid beta-protein has been found to have many different effects in the body, including receptor binding, ion channel activation and inhibition, and protein interactions. The peptide is also an activator for the high-affinity nicotinic acetylcholine receptor in the brain. This product can be used as a research tool or as an antibody to study amyloid beta protein in cellular biology.</p>

<p>Amino-dPEG®12-t-Butyl Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®12-t-Butyl Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Biotin-dPEG®4-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Biotin-dPEG®4-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>Anti IL-1beta (Rat) Serum is a kind of research tool. It can be used for the study of ion channels, receptors and ligands. This product can also be used to study protein interactions and peptides. Anti IL-1beta (Rat) Serum is a high purity antibody that is suitable for research or use in cell biology, pharmacology or other fields.</p>

<p>Please enquire for more information about Biotinoyl-2-Aminobutyric Acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>IL-1α is a cytokine that belongs to the group of proinflammatory cytokines. It plays a role in the immune response and inflammatory reactions by inducing the synthesis of other cytokines, such as IL-6, IL-8, and TNF-α. IL-1α binds to its receptor on a cell surface and activates an intracellular signalling cascade. The binding of IL-1α to its receptor induces conformational changes in the receptor, which leads to activation of phospholipase C (PLC) and production of IP3. This process results in increased levels of calcium ions inside the cell and activation of protein kinases such as PKC, MAPKs and JNKs. This results in increased activity of enzymes such as cyclooxygenase and lipoxygenase, which are responsible for inflammatory responses.</p>

<p>Bz-Gly-Lys is a peptide that is a derivative of lysine residues. This peptide can compete with the natural substrate, L-lysine, for binding to the active site of creatine kinase and inhibit its enzymatic activity. Bz-Gly-Lys has been shown to be effective in inhibiting monoclonal antibody production in human serum. Furthermore, this peptide can also have inhibitory properties on cell culture and may be useful in the treatment of diabetic patients. The optimum pH for Bz-Gly-Lys is neutral, and hydrolysis by proteases is required for it to be active. It has been shown to inhibit polymerase chain reaction (PCR) procedures. In addition, this peptide has been shown to enhance the inhibitory properties of fatty acids on cell culture.</p>

<p>Beta-Defensin-1 (BD-1) is an antimicrobial peptide that is produced by various cells and tissues in mice, including epithelial cells in the skin, lungs, and intestines. BD-1 is a member of the beta-defensin family, which are small cationic peptides that play a role in innate immunity by protecting against microbial pathogens, including bacteria, fungi, and viruses.<br>In mice, BD-1 is constitutively expressed, meaning that it is produced at a relatively constant level in healthy animals. Its expression can be induced by various stimuli, including bacterial and viral infections, cytokines, and inflammatory mediators.<br>BD-1 is known to have broad-spectrum antimicrobial activity against a variety of pathogens, including Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. It achieves its antimicrobial activity by disrupting the cell membranes of the pathogens, leading to cell lysis and death.<br>In addition to its antimicrobial activity, BD-1 has been found to have other functions in mice, including promoting wound healing, regulating inflammation, and modulating the immune response.</p>

<p>MonoFITC RLN3 is a labelled form of relaxin that can be used to measure the clearance of relaxin in tissue culture. It can also be used for quantification and localization of peptide receptors in tissues.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>

<p>Custom research peptide; min purity 95%.</p>