Peptidi

<p>The activation of transient receptor potential cation channel subfamily V member 1 (TRPV1) is believed to play a role in hyperalgesia, asthma and hypertension. TRPV1 is important for neuronal pain detection as well as the detection of heat, capsaicin, protons and the neurotransmitter anandamide. -The scaffold protein AKAP79 targets kinases to phosphorylate TRPV1, however it has been shown that inflammatory intermediates prostaglandin-E2 or bradykinin can activate these kinases creating a route for inflammation to cause hyperalgesia.This product is composed of the TRPV1 interacting domain of AKAP79 reordered into a scrambled sequence and conjugated to the cell penetrating TAT domain. This product was shown in vivo to have no effect on TRPV1 algesia and thus is a vital control for research work. This product is a vital tool for research into suitable TRPV1 antagonists.</p>

<p>Fmoc-Val-Wang Resin (100-200 mesh) 1% DVB is a resin that is used in the synthesis of peptides. The resin contains Fmoc-protected amino acids, which are cleaved by the use of hydrogen fluoride to release the free acid form. This resin is characterized by its high purity and low viscosity. It has been shown to be an excellent building block for peptide synthesis, as well as a useful tool for biological studies.</p>

<p>Urate oxidase is a flavoenzyme that catalyses the oxidation of uric acid to allantoin. It is present in many organisms, including fungi and primates. Urate oxidase catalyzes the oxidation of uric acid to allantoin via the reduction of oxygen to water with concomitant production of hydrogen peroxide. There are four forms of urate oxidase found in nature: tetrameric, dimeric, monomeric, and recombinant. The recombinant form has been shown to be effective against hyperuricaemia in primates and humans with lymphoid malignancies.</p>

FGF-2 is a protein that belongs to the FGF family. It is an activator of erythropoietin, which stimulates the production of red blood cells. FGF-2 also acts as a ligand for FGFR1 and FGFR2, which are receptors for FGF-2. The binding of FGF-2 to these receptors leads to a cascade of cellular responses by activating different types of ion channels and proteins involved in cell proliferation and differentiation. This protein is purified from mouse sources with high purity and no detectable endotoxin levels.

<p>Peptide H-GLFIIDGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Met-Leu-pNA (Hydrochloride Form) is a peptide that binds with high affinity to the N-methyl-D-aspartate receptor, an ion channel protein. It is used in research tools and as an inhibitor. The peptide has been shown to inhibit the activity of the receptor by competitive inhibition, preventing binding of glutamate, which normally activates the ion channel. This inhibition leads to a decrease in neuronal excitability and decreased production of proinflammatory cytokines.</p>

<p>Peptide Cyc-Biot-CGKGRGLC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-FLASVSTVLTSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Melanocyte Stimulating Hormone (MSH) and Related Peptides are a group of peptides that have a role in the regulation of skin pigmentation. One such peptide is Nle4, D-Phe7]-ß-MSH-amide, which is an agonist of melanocortin receptors. It has been shown to stimulate the proliferation and cause the differentiation of melanocytes in vitro, as well as to increase the number of melanocytes in vivo.

H-Ala-Phe(para-Fluoro)-Arg-Cha-Cit-Tyr-NH2 is a peptide that has been shown to activate Protease Activated Receptor 1 (PAR1). PAR1 is the receptor for thrombin, which is the enzyme responsible for blood clotting. The peptide was found to be a potent activator of PAR1 in vitro and in vivo. It has also been shown to inhibit the production of angiotensin II, which can lead to hypertension. H-Ala-Phe(para-Fluoro)-Arg-Cha-Cit-Tyr-NH2 is a potential candidate for treating cardiovascular diseases such as hypertension.

<p>Z-Gln-Gly-OH is a synthetic dipeptide, which is a modified amino acid sequence commonly used in biochemical applications. It consists of a carbobenzoxy-protected glutamine and a glycine residue. This compound originates from custom organic synthesis, derived through specific chemical protocols to introduce protective groups that block reactive sites on the amino acids. This controlled modification alters the peptide's stability and solubility.The mode of action involves the protection of active sites during complex syntheses, enabling the sequential construction of peptide chains without unintended reactions. This protection is critical in solid-phase peptide synthesis methodologies where precision and specificity of reactions are paramount. The Z-group (benzyloxycarbonyl) ensures the stability of glutamine under various chemical conditions, preventing side reactions that may compromise the integrity of peptide constructs.In research, Z-Gln-Gly-OH finds applications in the design of peptide-based inhibitors, structural studies, and the synthesis of longer chain peptides that mimic biologically relevant structures. The protection strategy allows scientists to develop and manipulate peptides with high fidelity, facilitating advancements in understanding protein functions and interactions in physiological contexts.</p>

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

<p>H-Leu-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin that has been used to synthesize peptides. It can be used as a building block for many other chemical reactions, such as cross-linking and oxidation. This resin is typically used in the synthesis of peptides with an amino acid sequence of H-Leu-2-ClTrt and contains 1% DVB. The resin can be used for the synthesis of small organic molecules, such as antibiotics, with a molecular weight between 500 and 2000 Da.</p>

<p>Liver-Expressed Antimicrobial Peptide 2 (LEAP2) is a peptide that belongs to the family of antimicrobial peptides. LEAP2 is a potent activator of ion channels, which are membrane proteins that regulate the passage of ions through the cell membrane. LEAP2 can also inhibit protein interactions by binding to receptors and ligands on the surface of cells. LEAP2 has been shown to be a receptor for Ligand-gated ion channels, which are involved in many cellular processes such as neurotransmitter release, muscle contraction, and hormone release.<br>LEAP2 can be used as an inhibitor of the hyperpolarization activated cyclic nucleotide-gated (HCN) channels in neurons. These channels are important for regulating neuronal excitability and inhibiting neuronal activity following action potentials.</p>

<p>Peptide H-VSFEDSVISLSGDHSIIGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-YLPNPALQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-DLPMSPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

H-Tyr-AMC is a synthetic substrate that is used in the study of serine proteases. It is reversibly bound to Sephadex G-100 and is hydrolyzed by protease enzymes in an acidic environment, generating an AMC chromatographic peak. This product has been shown to inhibit serine protease activity and, when incubated with the enzyme, reduces the hydrolysis of synthetic substrates. Synthetic H-Tyr-AMC can be used to study the inhibition of serine proteases by various inhibitors and their binding sites on the enzyme.

<p>HCV NS3 protease FRET substrate</p>

<p>Mob-S-Mercaptoproprionic acid is a reagent that can be used to synthesize peptides. It is also a Building Block for the synthesis of other molecules. Mob-S-Mercaptoproprionic acid is hydrolyzed to form the corresponding carboxylate and mercaptoacyl amide, which can be used in peptide synthesis by condensation with an amino acid.</p>

<p>H-D-Ala-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin for the synthesis of peptides. It is an amino acid resin with D,L-alanyl side chains, which can be cleaved by hydrochloric acid to release the desired amino acid and trityl resin. This resin is used in peptide synthesis reactions to provide a protecting group for the N-terminal amino acid.</p>

Peptide H-VAIYEEFLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Des-n-Octanoyl-[Ser3]-Ghrelin (Human, 1-18) is a non-acylated analog of Ghrelin (Human, 1-18), amino acids 1-18 of the peptide hormone Ghrelin. This peptide does not contain the unique N-octanoyl group which is linked to Ghrelin's third serine residue covalently and which allows Ghrelin to associate with the growth hormone secretagogue receptor (GHS-R). Through interaction with the GHS-R, Ghrelin can exert its various effects on the body such as stimulating appetite, nutrient sensing, meal initiation and the regulation of insulin resistance, diabetes and obesity. Its wider functions are also associated with glucose homeostasis, energy homeostasis, cardio-protective effects, bone metabolism and its potential to be a target for cancer means that it can be used to develop therapies for a whole spectrum of diseases. This molecule is used as a research tool for studying cell biology and pharmacology.</p>

Peptide H-FLPFQQFGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide H-LNILNNK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

H-Trp-Arg-OH·2 HCl is a reagent that is used in the synthesis of peptides and other organic compounds. It is a complex compound with CAS No. 276880-00-3. This chemical has been shown to be useful as an intermediate, a fine chemical, and a speciality chemical for research purposes. H-Trp-Arg-OH·2 HCl has been found to be a versatile building block or reaction component in the preparation of various pharmaceuticals and other organic compounds.

Fmoc-D-Glu(OtBu)-Wang resin is a solid support for peptide synthesis. It is used to synthesize peptides with the Fmoc or O-benzyl protecting group. The resin has a 1% DVB content and an average particle size of 100-200 mesh.

<p>Peptide H-LSALTPSPSWLKYKAL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide Ac-YEVHHQKLVF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

A human truncated analog of Obestatin, a 23 amino acid gastrointestinal peptide, encoded for by the ghrelin gene and is known to reduce food intake through supressing appetite. This peptide has been found to influence the pancreas, cardiovascular system and adipose tissues as well as the gastrointestinal system. One study showed that when high-fat diet fed rats were given chronic administration of obestatin it prevented the development of non-alcoholic fatty liver disease. Consequently Obestatin has the potential to be used in preventing obesity-related diseases.

<p>Boc-L-Glutamic Acid bis-Propargyl Amide is a building block for Click Chemistry. It is a white solid that is soluble in DMF, DMSO and other organic solvents. This product can be used as a reagent for peptide synthesis and as an intermediate for the synthesis of amino acids. Boc-L-Glutamic Acid bis-Propargyl Amide reacts with dimethylaminoethanol to form the corresponding amide. It has been shown that this product can be used in click chemistry reactions to form amides and ureas.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

Fmoc-Pro-Wang Resin (100-200 mesh) is a resin that can be used for peptide synthesis. It is a building block for the synthesis of peptides, proteins and other organic compounds. Fmoc-Pro-Wang Resin (100-200 mesh) 1% DVB is an acid labile resin that is polymerized with N,N'-Dicyclohexylcarbodiimide and 4-(dimethylamino)pyridine to form a three dimensional crosslinked network. This resin has 100-200 mesh particle size and 1% DVB content.

<p>Ac-Pro-Arg-Asn-Lys-Acc-NH2 is a peptide that is used to study the catalytic mechanism of enzymes. It has been shown to be an effective substrate for tryptase, which is an enzyme that plays a role in the degradation of proteins. Ac-Pro-Arg-Asn-Lys-Acc-NH2 binds to the active site of tryptase and undergoes a series of reactions that lead to its hydrolysis. The rate constants for these reactions have been measured in order to determine kinetic constants.</p>

<p>GpTX-1 is a synthetic 34 amino acid peptide derived from tarantula spider venom. Due to its antagonist activitiy against voltage gated sodium channels such as Na v1.7, it can be used as a possible therapeutic in inflammatory, neuropathic, visceral and nociceptive pain treatment. DpTX-1 has also been found to block voltage-dependent calcium channels.<br>One-Letter Formula: H-DCLGFMRKCIPDNDKCCRPNLVCSRTHKWCKYVF-NH2</p>

Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] is a peptide that contains the RGD sequence. It is a synthetic cyclic peptide that has been shown to bind to integrin receptors, which are cell surface receptors found in many cells. These integrins are involved in cellular adhesion and signaling. Cyclo[Arg-Gly-Asp-D-Phe-Lys(Azide)] can be used as a tool for click chemistry, as it can be modified with other molecules such as azides, which can then be used for click reactions with other molecules. This peptide has also been shown to have biological activity against cancer cells and inflammation.

<p>Cyclo[Arg-Gly-Asp-D-Phe-Lys(Mal)] is a peptide, or small protein, that has been shown to have anti-inflammatory and anti-tumor activities. Cyclo[Arg-Gly-Asp-D-Phe-Lys(Mal)] is a cyclic peptide with three maleimidopropionic acid residues and contains the amino acid sequence Arg - Gly - Asp - D - Phe - Lys (Mal). The peptide has been shown to inhibit the production of nitric oxide in macrophages by blocking the release of arginase from these cells. This inhibition of arginase leads to decreased production of nitric oxide, which is an important mediator in inflammation. Cyclo[Arg-Gly-Asp-D-Phe-Lys(Mal)] also inhibits tumor cell proliferation through its ability to inhibit protein synthesis and induce apoptosis.</p>

IL-2 is a cytokine that regulates the immune system. It is a protein that is produced by T lymphocytes and natural killer cells, and stimulates the production of other white blood cells. IL-2 has two receptor chains: an alpha chain that binds to IL-2 and a beta chain that binds to IL-2 with high affinity. The receptor chains are encoded by genes in the human major histocompatibility complex (MHC) on chromosome 6. IL-2 has been shown to be an activator of ion channels and ligand for antibody molecules. It also has been used as a research tool in cell biology and as an inhibitor for cancer treatment.br>br> IL 2 Human is a recombinant form of Interleukin 2, which is a type of immunotherapy that is used to treat cancer patients who have not responded well to chemotherapy or radiation therapy. This form of Interleukin 2 is purified from E. coli bacteria, which means it does

<p>Cyclo(Arg-Gly-Asp-D-Tyr-Cys) is a peptide that is used as a research tool to study the activation of ion channels. It activates the channel by binding to the receptor and inducing conformational changes in it. Cyclo(Arg-Gly-Asp-D-Tyr-Cys) is also used as an inhibitor of protein interactions, such as antibody and ligand interactions. CAS No.: 438286 28</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>This product is an RGD Peptide containing a Thioacetyl Group for Linking to Liposomes. It may require further derivatization and deprotection before use</p>

<p>[N-Me-Asp1]-Angiotensin II is a peptide that belongs to the peptides and biochemicals group. It is an angiotensin II antagonist, which means that it blocks the action of Angiotensin II on its receptors. This peptide can be used as a vasoconstrictive agent in the treatment of hypertension.</p>

<p>Peptide H-DQFPEVYVPTVFENYVADIEVDGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

Peptide H-VGVNGFGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide Ac-CVYVRSAIQLGNYK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

<p>Peptide H-IATALVDTFAVAR^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DGLILTSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-DFDQNQGEVVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>