Peptidi

A Hemopexin Light Tryptic Peptide Standard for use in protein identification and quantitation applications. Hemopexin is a protein found within the plasma which has a high binding affinity for heme.

Z-Val-Ala-Asp(OMe)-CH2F is a peptide that belongs to the ion channel inhibitor family. It has been shown to inhibit potassium channels and voltage-gated sodium channels, which are important for regulating the flow of ions in cells. Z-Val-Ala-Asp(OMe)-CH2F has also been shown to bind to the receptor for tumor necrosis factor α and downregulate its activity. Z-Val-Ala-Asp(OMe)-CH2F is a useful tool for studying protein interactions and cellular processes such as apoptosis, inflammation, and cell growth.

Peptide H-FIFYLKNIV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

D-Arginyl-[Hyp3,Thi5,8,D-Phe7]-Bradykinin is a peptide that is used as a pharmacological research tool. It has been shown to activate certain ion channels and bind to certain receptors. This compound has also been shown to inhibit the binding of some ligands to their receptors. D-Arginyl-[Hyp3,Thi5,8,D-Phe7]-Bradykinin has been purified from the venom of a scorpion species Daboia russelii. This peptide is a potent inhibitor for atrial natriuretic peptide receptor B (NPRB).

dPEG®12-SATA Acid (S-Acetyl-dPEG®12-Acid) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. dPEG®12-SATA Acid (S-Acetyl-dPEG®12-Acid) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

An Apolipoprotein B heavy tryptic peptide standard for use in protein identification and quantitation studies. Apolipoprotein B is responsibly for carrying lipids such as low density lipoprotein (LDL), chylomicrons, intermediate-density lipoprotein, very low-density lipoprotein and lipoprotein (a).

TentaGel® Macrobead-NH2 Resin (Particle size: 140-170 µm) is a building block for peptide synthesis. It is a resin of crosslinked polystyrene macroparticles with an average particle size of 140-170 µm. TentaGel® Macrobead-NH2 Resin (Particle size: 140-170 µm) is used as a solid support in peptide synthesis. The resin is made up of crosslinked polystyrene macroparticles that are insoluble in water and organic solvents, making it particularly suitable for use as a solid support in peptide synthesis.

Angiotensin Light Tryptic Peptide Standard f use in protein identification and quantitation studies. Angiotensin is a peptide hormone that causes vasoconstriction and is responsible for an increase in blood pressure. Furthermore angiotensin stimulates aldosterone release.

Pyr-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu is a lysine based peptide. It is an activator of the GABA receptor, which mediates inhibitory neurotransmission in the central nervous system. Pyr-Lys-Arg Pro Ser Gln Arg Ser Lys Tyr Leu has been shown to bind to the alpha2/delta subunit of the GABA receptor and increase its affinity for GABA. This peptide has also been shown to be an inhibitor of glutamate receptors.

Borrelia Burgdorferi Basic Membrane Protein A (BBMPA) is a protein that belongs to the Borrelia burgdorferi bacterium. It is a glycoprotein found on the surface of the bacterial cell, which has been shown to be involved in adhesion to host tissue. BBMPA is composed of two identical subunits, each containing five domains. These domains are involved in different functions and range from binding to other proteins and lipids to receptor-binding sites for host cells. This protein has been studied extensively as it is important for pathogenicity and infectivity of Borrelia Burgdorferi.

Cy5 Biotin can be used for detecting and quantifying biotin binding sites of avidin, streptavidin or neutravidin. It is water soluble and its red fluorescence is pH independent from pH 4 - 10.  The PEG3 spacer between biotin moiety and fluorescent tag minimize steric hindrance involved in binding to avidin, streptavidin or neutravidin.Abs/Em Maxima:  649/671 nmExtinction Coefficient: 250,000

This is a Von Willebrand Factor Light Tryptic Peptide Standard for use in protein identification and quantitation. Von Wilebrand Factor is a glycoprotein involved in platelet adhesion and when it is deficient in the body it can result in diseases such as von Willebrand disease.

Hydroxyacyl-Coenzyme A Dehydrogenase is an enzyme that catalyzes the oxidation of hydroxyacyl-CoA to form acetyl-CoA. It is a member of the short-chain dehydrogenases/reductases (SDR) superfamily. Hydroxyacyl-Coenzyme A Dehydrogenase is expressed in many tissues and has been shown to be essential for fatty acid synthesis and catabolism, as well as for the conversion of ketone bodies to acetyl-CoA. It also plays a role in cellular respiration and energy production.

Please enquire for more information about Atrial natriuretic factor (1-28) (human) acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

A Ceruloplasmin Light Tryptic Peptide Standard for use in protein identification and quantitation studies. Ceruloplasmin is a serum ferroxidase key to transporting copper in the blood. It also plays a role in iron metabolism regulation and the pathogenesis of Wilson disease. Furthermore it has been found in elevated levels during inflammation.

Cyclin-Dependent Kinase Inhibitor 2A (CDK2A) is a cyclin-dependent kinase inhibitor that inhibits the activity of cyclin-dependent kinases. CDK2A is a protein that belongs to the family of cyclin-dependent kinase inhibitors. It inhibits the activity of various cyclin-dependent kinases and prevents cell growth by suppressing protein synthesis. CDK2A is expressed in many human tissues, including erythrocytes, brain, heart, lung, muscle, pancreas, spleen, and testis. Cyclin-Dependent Kinase Inhibitor 2A can be used as an anti-cancer agent due to its ability to inhibit tumor proliferation.

Please enquire for more information about TentaGel® Macrobead RAM particle size: 140 - 170 µm including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about L-Cysteinyl-L-lysine trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Angiotensin IV trifluoroacetate is an active analogue of angiotensin. It has been shown to have a high affinity for AT1 receptors and is able to enhance the uptake of angiotensin in proximal tubules, which may be due to its ability to bind DNA. Angiotensin IV trifluoroacetate has also been shown to have beneficial effects on skin cells, such as the reduction of skin inflammation and alleviation of pain. Angiotensin IV trifluoroacetate has shown anti-inflammatory activities, which may be due to its ability to reduce pro-inflammatory cytokines such as IL-6 and TNF-α. This drug also binds to the CD4 receptor, thereby inhibiting inflammatory responses in autoimmune diseases.Mass spectrometry of peptides and proteins using digestion by a grape cysteine protease at pH 3Z Perutka, M Å ebela - Journal of mass spectrometry, 2020 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/jms.4444Integrating computational modeling and experimental assay to discover new potent ACE-inhibitory peptidesY Ren, Q Wang, S Chen, H Cao - Molecular Informatics, 2014 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/minf.201300131Absorption of casein antihypertensive peptides through an in vitro model of intestinal epitheliumM del Mar Contreras , AI Sancho , I Recio, C Mills - Food Digestion, 2012 - Springerhttps://link.springer.com/article/10.1007/s13228-012-0020-2Enhanced recombinant expression and purification of human IRAP for biochemical and crystallography studiesL Sui , HC Guo - Biochemistry and Biophysics Reports, 2021 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S2405580821001369The specific isolation of C-terminal peptides of proteins through a transamination reaction and its advantage for introducing functional groups into the peptideK Sonomura, H Kuyama , E Matsuo - Journal Devoted to , 2009 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/rcm.3920Fragmentation mechanisms of oxidized peptides elucidated by SID, RRKM modeling, and molecular dynamicsJM Spraggins , JA Lloyd, MV Johnston , J Laskin - Journal of the American , 2009 - Springerhttps://link.springer.com/article/10.1016/j.jasms.2009.04.012Gold ion-angiotensin peptide interaction by mass spectrometryJ Lee, LP Jayathilaka, S Gupta - Journal of the , 2012 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1007/s13361-011-0328-0Structure-activity study of LVV-hemorphin-7: angiotensin AT4 receptor ligand and inhibitor of insulin-regulated aminopeptidaseJ Lee , T Mustafa, SG McDowall - of Pharmacology and , 2003 - ASPEThttps://jpet.aspetjournals.org/content/305/1/205.shortA mechanistic investigation of the enhanced cleavage at histidine in the gas-phase dissociation of protonated peptidesG Tsaprailis, H Nair, W Zhong , K Kuppannan - Analytical , 2004 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ac034971jStudy of secondary specificity of enteropeptidase in comparison with trypsinAG Mikhailova, VV Likhareva, BV Vaskovsky - Biochemistry , 2004 - Springerhttps://link.springer.com/article/10.1023/B:BIRY.0000040224.47278.3b

GaTx2 is a costimulatory molecule that binds to the B7-1 and B7-2 receptors on the surface of antigen-presenting cells. GaTx2 has been shown to regulate transcriptional regulation, cellular growth, and physiological function in heart tissue. It is also involved in the development of cancer and autoimmune diseases. GaTx2 has biological properties that are similar to those of T lymphocyte growth factor (TGF) and basic fibroblast growth factor (bFGF). GaTx2 is also a whole-cell voltage clamp that can be used in tissue culture.

Huwentoxin IV is a potent analgesic that has been shown to have antinociceptive properties in animals. Huwentoxin IV blocks the voltage-gated sodium channel NaV1.8 and prevents the transmission of pain signals to the brain. This drug has also been shown to inhibit the activity of voltage-gated potassium channels KV1.3 and KV1.5, which are involved in neuronal excitability, suggesting that huwentoxin IV may have other therapeutic applications. Huwentoxin IV interacts with disulfide bonds and is an effective inhibitor of voltage-gated sodium channels, but not voltage-gated potassium channels, at low concentrations (10 μM).

As a member of the tachykinin neuropeptide family, Neurokinin B is involved in the dilation of blood vessels, the contraction of smooth muscles and the excitation of neurons. This product can be applied as a NK3 receptors selective agonist.

Oxytocin is a peptide hormone and neurotransmitter. It is primarily used in the brain to regulate social behavior, such as maternal behaviour, sexual arousal and romantic attachment. Oxytocin is also used for uterine contractions during childbirth and to induce labour. Oxytocin can be administered by injection or as nasal spray. It has a half-life of about two minutes in the blood stream and its effects last up to one hour. Oxytocin is a nonapeptide with the amino acid sequence: Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-Leu-Met-(OH). The oxytocin receptor (OXTR) belongs to G protein coupled receptors (GPCR), which are known for their roles in cell signaling, oncogenesis, immunity, inflammation, pain sensation and endocrine regulation. The OXTR is expressed throughout the body including the uterus and vagina.

Please enquire for more information about Amyloid β (1-42) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Insulin-like 5 (INSL5) is a protein that in humans is encoded by the INSL5 gene. It belongs to the insulin family of proteins and has been shown to have a role in various biological functions. INSL5 binds to the insulin receptor, which induces apoptosis in cancer cells by inhibiting cyclin-dependent kinase activity and inducing cell cycle arrest. The expression of INSL5 can be used as a diagnostic marker for cervical cancer and may also be used as a potential biomarker for cancer tissues.

Human CRF ELISA (1ea) is a high-quality, competitively priced ELISA kit for the quantitative measurement of human CRF in rat serum. This assay has been designed for use in detecting the presence of CRF in biological fluids for research purposes. The kit contains all necessary components to perform the assay and detailed instructions are included.

IL-17 Rat is a recombinant protein that is used as an immunological research tool. It is also used as a ligand to study the IL-17 receptor. IL-17 is a cytokine that activates cells in the immune system, such as T cells, B cells, and natural killer cells. This protein can be used in cell biology experiments to study cytokine signaling pathways and has been shown to inhibit ion channels. IL 17 rat can also be used in pharmacology studies to assess its effects on peptides and proteins within the body.

Peptide H-WLGFIAGLIAIVMVT-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Peptide H-WYIWLGFIAGLIAIV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Cntf is a cytokine that belongs to the family of neurotrophins. It is a ligand for the receptor c-ret, which is expressed in cells of the central and peripheral nervous system. The Cntf protein can be used as an activator or inhibitor in cell biology and pharmacology research. The Cntf mouse has been created by fusing a human c-ret gene with a mouse agouti gene. This mouse has high levels of Cntf protein and can be used to study the effects of this protein on ion channels, cell biology, and other areas of research.

Catestatin is a peptide that belongs to the family of activators. Catestatin is an activator of potassium channels and can be used as a research tool. It has been shown to bind to the Kv1.2 receptor, which is expressed in human heart and skeletal muscle cells. This peptide also inhibits calcium-activated potassium channels, thereby blocking the transmission of nerve impulses. Catestatin has been shown to inhibit protein interactions with G protein-coupled receptors (GPCRs) and ion channels, thereby regulating cellular signaling pathways involved in cell growth and differentiation.

Nucleolin is a protein that belongs to the nucleolar family of ribonucleoprotein. It has been shown to be involved in the transcription, maturation, and fibrillar assembly of ribosomal RNA. Nucleolin also plays an important role in the synthesis of other proteins by serving as a scaffold for the assembly of pre-ribosomal particles. The c-terminal domain contains a phosphoprotein called PNPase that catalyzes the hydrolysis of inositol polyphosphates. In addition, nucleolin is glycosylated during its maturation process.

Complement Component C5a Mouse (recombinant) is a recombinant protein that is an activator of the complement system. It can be used to investigate the role of the complement system in immune responses, inflammation, and cell death. Complement component C5a mouse (recombinant) is a potent inhibitor of ion channels and ligand-gated receptors, and has been shown to inhibit the function of voltage-gated potassium channels. Recombinant Complement component C5a mouse (recombinant) can also be used as an antibody probe for immunohistochemical detection of C5a receptor protein expression in cells. Complement component C5a mouse (recombinant) has high purity and is suitable for research purposes.

Insulin-like growth factor 1 (IGF1) is a cytokine that belongs to the family of growth factors. IGF1 is a peptide hormone that mediates its effects by binding to cell surface receptors and activating signal transduction pathways inside cells. IGF1 stimulates glucose uptake, protein synthesis, and lipolysis in muscle and adipose tissue. The A67T variant of IGF1 has been shown to have increased activity in stimulating insulin-like signaling pathways and mediating the effects of IGF1 on glucose metabolism. This variant is associated with increased risk for type 2 diabetes mellitus (DM).

IP-10 is a chemokine that is expressed in the human immune system. IP-10 can be released from cells such as macrophages, neutrophils, and mast cells in response to inflammatory stimuli. This protein is important for the recruitment of lymphocytes and monocytes to sites of infection or injury. IP-10 also has antitumor activity, which may be due to its ability to induce apoptosis in tumor cells.

Lipid A is a bacterial endotoxin that activates macrophages and dendritic cells, which in turn activate T-cells. It is a ligand for the CD14 receptor, which is a pattern recognition molecule found on macrophages and dendritic cells. Lipid A also binds to the Toll-like receptor 4 (TLR4) on host cells, initiating an inflammatory response. Lipid A has been used as a research tool to study cell biology related to activation of macrophages and dendritic cells leading to cytokine production. This activator has also been used as a ligand in antibody studies, ion channel studies, protein interactions, pharmacology experiments with peptides, and life science research.

The anti G-protein: Galpha i3 (105-127) is a recombinant human serum protein. This antibody was raised against the peptide sequence of human Galpha i3 (105-127). It has been purified by Protein A and gel exclusion chromatography. The peptide sequence of this antibody is as follows: YGRKKRRQRRRPPPPPPRRRQRRKSSSSSEEEEDEESDS.

SPDP-dPEG®8-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. SPDP-dPEG®8-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

TNF-α is a cytokine that is produced by many cells, including macrophages, T cells, mast cells, and synovial cells. It is a pleiotropic proinflammatory cytokine that has been implicated in cancer and other inflammatory diseases. TNF-α is a potent inducer of cell death through activation of the Fas-FasL death pathway or induction of apoptosis. In addition to its role as an anti-tumor agent, TNF-α has been shown to be important in the regulation of immune responses and inflammation. It also plays an important role in bacterial sepsis by suppressing the production of proinflammatory cytokines such as IL-1β and IL-12 by macrophages.

EREG Human is a cytokine that belongs to the group of proteins. It is an interleukin-1 receptor antagonist (IL-1Ra) that binds to IL-1 and prevents it from binding with its receptors. EREG Human has been shown to be effective in treatment of inflammatory diseases such as Crohn's disease, rheumatoid arthritis, and ulcerative colitis.

IL-11 is a cytokine that is synthesized by cells of the immune system and functions as an autocrine growth factor for cells of the myeloid lineage. IL-11's receptor is a protein that binds to the IL-11 peptide and this binding activates intracellular signaling pathways.

SPAI-1 is a protein that is found in the cytosol and nucleus of cells. It belongs to the family of inhibitor proteins, which regulate the activity of other proteins. SPAI-1 inhibits the activity of many different types of protein kinases. Inhibitors such as SPAI-1 are often used as research tools for studying protein interactions, activators, ligands, and receptors. This antibody can be used as a reagent to detect and locate SPAI-1 in cells or tissues by immunohistochemistry.

FRETS-25Arg (1 umol) is a peptide that has been shown to activate the serotonin 2C receptor. The peptide is a high purity product with a CAS number of 9078-02-5. FRETS-25Arg (1 umol) can be used as a research tool for studying the protein interactions, receptor binding, and ion channels.

Secretin (Porcine) Antiserum is a research tool that is used to activate the secretin receptor. Secretin is an inhibitor of ion channels, which may be due to its ability to bind to the secretin receptor and inhibit its activity. The purified protein has a high purity and can be used in antibody experiments, cell biology, or pharmacology.