Peptidi
Sottocategorie di "Peptidi"
Trovati 29608 prodotti di "Peptidi"
Acetyl-Alpha-2-antiplasmin-[AF680]
Alpha-2-antiplasmin (alpha2AP), a member of the serine protease inhibitor (SERPIN) superfamily, is the main inhibitor of the fibrinolytic enzyme plasmin as well as an inhibitor of trypsin, elastase, and C protein. It plays a crucial role in reducing plasmin production and activity and thus inhibiting fibrinolysis.alpha2AP is synthesized in the liver and secreted as a single-chain glycoprotein, containing 11-14% carbohydrate, with a methionine (Met) as its N-terminus (Met-alpha2AP). The N-terminus of alpha2AP is involved in the incorporation of alpha2AP into a clot and the C-terminus is involved in the initial interaction of alpha2AP with plasmin(ogen). Circulating alpha2AP undergoes both N-and C-terminal modifications, which alter its activity. Increased concentrations of a2AP are associated with a higher risk of cardiovascular diseases.Purezza:Min. 95%Peso molecolare:2,735.2 g/molH-NAGVILAPLQR^-OH
Peptide H-NAGVILAPLQR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-ETLLQDFR^-OH
Peptide H-ETLLQDFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[5-FAM]-Galanin (2-30)-[Cys] (Human)
Galanin is predominantly an inhibitory neuropeptide expressed in humans and other mammals' brains, spinal cords, and gut. Galanin signalling occurs through three G protein-coupled receptors. The functional role of galanin remains largely unknown- however, galanin is predominantly involved in the modulation and inhibition of neuron action potentials. Galanin has been implicated in many biologically diverse functions, including nociception, waking and sleep regulation, cognition, feeding, mood regulation and blood pressure regulation. Galanin appears to have neuroprotective activity as its biosynthesis is increased 2-10 fold upon axotomy and during seizure activity in peripheral tissues and the brain.The clinical relevance of galanin is related to several chronic neural disorders, including Alzheimer's disease, epilepsy, depression and cancer those who suffer from type 2 diabetes mellitus, depression and Alzheimer's disease often express high levels of galanin. Conversely, intervention with galanin agonists (for example, M617, M1145 and M1153) manifests anti-insulin resistance and anti-Alzheimer's disease characteristics and ameliorates or reinforces depression-like behaviour. Specifically, activation of GAL2 can alleviate such disease features in human and rodent models. This galanin (2-30) peptide has been used to characterise Galanin's binding sites and affinity for GALR receptors via competition binding analysis. Galanin (2-30) is a full agonist of the GALR2 receptor compared to its affinity for GALR1.Galanin (2-30) is provided with an N-terminal 5-FAM, a widely used green fluorescent reagent ideal for peptide labelling and detection and a C-terminal cysteine for site-specific conjugation. The excitation/emission for this reagent is 490 nm/520 nm.Colore e forma:PowderPeso molecolare:3,558.6 g/molACTH (1-39) Human
Human adrenocorticotropic hormone (ACTH) also known as corticotropin. ACTH is a tropic hormone produced and secreted by the anterior pituitary gland and member of the melanocortins peptide family. ACTH is cleaved from the precursor proopiomelanocortin (POMC). ACTH is an important component of the hypothalamic-pituitary-adrenal (HPA) axis and is often produced in response to biological stress. ACTH acts to increase the production and release of cortisol via its interaction with the ACTH receptor ACTHR, also known as melanocortin type 2 receptor (MC2R). Receptor activation increases the intracellular concentration of cAMP via adenylyl cyclase.Abnormal ACTH levels in the body has been linked to primary adrenal insufficiency/Addison's disease, Cushing's disease and secondary adrenal insufficiencyColore e forma:PowderPeso molecolare:4,541.07 g/molH-GVVVMIPSYALHR^-OH
Peptide H-GVVVMIPSYALHR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-GAVDPLLAL^-OH
Peptide H-GAVDPLLAL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VYKPSAGNNSLYR^-OH
Peptide H-VYKPSAGNNSLYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Urokinase-Derived Peptide A6
Urokinase-Derived Peptide A6 (UDP-A6) is a protein derived from the urokinase enzyme. It has been shown to have antiproliferative effects on tumour cells and has been studied as a potential treatment for inflammatory diseases such as rheumatoid arthritis. The mechanism of action is not fully understood, but it is thought that UDP-A6 binds to a specific receptor on the surface of cells, called the leukocyte antigen, which causes them to stop proliferating. UDP-A6 has also been shown to bind to the surface glycoprotein of cancer cells and cause them to die.Formula:C39H62N10O15Purezza:Min. 95%Peso molecolare:910.99 g/molSuc-Ala-Pro-Ala-pNA
CAS:Suc-Ala-Pro-Ala-pNA is a synthetic substrate that inhibits serine proteases. It has been shown to inhibit thrombin, trypsin, and chymotrypsin at low concentrations. Suc-Ala-Pro-Ala-pNA is used as an anticoagulant in rat neutrophils and it has also been found to have chemotactic activity for neutrophils at high concentrations. The substrate was also found to be an efficient method of detecting the presence of protease activity in plant physiology experiments. In addition to its use as a proteinase inhibitor, Suc-Ala-Pro-Ala-pNA can also be used as an antiplatelet agent.Formula:C21H27N5O8Purezza:Min. 95%Peso molecolare:477.47 g/mol(Tos-GPR)2-[Rh110]
Fluorogenic substrate for thrombin that when in its intact state does not fluoresce, however upon cleavage by thrombin in 2 successive steps, Rhodamine 110 is released to allow fluorescence.Thrombin is a multifunctional serine protease and is the principal enzyme of hemostasis. It catalyzes the conversion of fibrinogen to fibrin and activates procoagulant factors V, VIII, XI, and XIII. When bound to thrombomodulin, it activates protein C, an anticoagulant zymogen. Thrombin also activates platelets, regulates endothelial cell function, and has a host of direct actions on other cells. Thrombin has been found to act as a mediator of vascular dysfunction and inflammation in both the peripheral and the central nervous systems. Thrombin contributes to the development of cardiovascular disease, atherosclerosis and diabetes and promotes vascular dysfunction, inflammation, and neurodegeneration. Thrombin is elevated in the brains of people with Alzheimer's disease (AD) and therefore may be a therapeutic target in AD.Purezza:Min. 95%Colore e forma:PowderPeso molecolare:1,259.42 g/molH-GSLQKR^GIVE-OH
Peptide H-GSLQKR^GIVE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.AYPGFK Protease-Activated Receptor-4 (PAR-4)
Protease activated receptors (PARs) are a distinctive four-member family of seven transmembrane G protein-coupled receptors (GPCRs) widely expressed in inflammatory cells. PARs are cleaved by certain serine proteases to expose a tethered ligand domain, this ligand domain then binds to and activates the receptors to initiate multiple signalling cascades. These PAR-activating proteases therefore represent PAR agonists. This PAR-4 agonist peptide represents the N-terminal sequence of the 'tethered ligand' and is therefore capable of activating the receptor independently of N-terminal proteolysis.Peso molecolare:680.4 g/molH-CKSKKFRRPDIQYPD-NH2 000-000-404
Peptide H-CKSKKFRRPDIQYPD-NH2 000-000-404 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-VSELTEEPDSGR^-OH
Peptide H-VSELTEEPDSGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-ISTLNSHNLPILR^-OH
Peptide H-ISTLNSHNLPILR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.[5-FAM]-RKOpep
Peptide identified through phage display that binds to colorectal cancer cell line RKO cells, as well as other cancer cells including Caco-2, HCT 116 and HCT-15, but not to normal cells, possibly through targeting the monocarboxylate transporter 1, which has been implicated in colorectal cancer progression and prognosis. It contains 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.Peso molecolare:1,278.4 g/molH-LRRFSTAPFAFININNVINF-NH2
Peptide H-LRRFSTAPFAFININNVINF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Fibrinogen γ-Chain (117-133)
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Formula:C84H147N25O27Peso molecolare:1,939.26 g/molH-SP^SYAYHQF-OH
Peptide H-SP^SYAYHQF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
(Trp63,Trp64)-C3a (63-77)
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFormula:C86H134N26O18Peso molecolare:1,820.17 g/molH-EDPQGDAAQK^-OH
Peptide H-EDPQGDAAQK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-GDYSHCSPLRYYPWWKCTYPDPEGGG-NH2
Peptide H-GDYSHCSPLRYYPWWKCTYPDPEGGG-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-HYGGLTGLNK^-OH
Peptide H-HYGGLTGLNK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.HPV 33 E6 64-72 (HLA-A*03:01)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolAoa-HHHHH-OH
Peptide Aoa-HHHHH-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SIVmac239 - 35
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecolare:1,621.9 g/molH-SQSENFEYVAFK^-OH
Peptide H-SQSENFEYVAFK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-GPSVFPLAP^SSK^-OH
Peptide H-GPSVFPLAP^SSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
CMVpp65 - 45 (EPDVYYTSAFVFPTK)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolPeso molecolare:1,764 g/molH-TITNDR^-OH
Peptide H-TITNDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-VGAHAGEYGAEALER^^-OH
Peptide H-VGAHAGEYGAEALER^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Bid BH3-r9 TFA
Catalogue peptide; min. 95% purityFormula:C151H272N70O42S•(C2HF3O2)xPeso molecolare:3,772.36 g/molHSV-gB2 (498-505)
CAS:Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFormula:C41H67N11O13Peso molecolare:922.06 g/molLeu-AFC.HCl
Aminopeptidase fluorogenic substrate. Upon cleavage of the bond between leucine and the 7-amino-4-trifluoromethylcoumarin (AFC) group an increase in fluorescence between 495-505nm can be detected using an excitation wavelength of 395-400nm.Peso molecolare:378.77 g/molH-IATEAIENFR^-OH
Peptide H-IATEAIENFR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Glucagon (1-29)-[Lys(AF647)]
Glucagon (1-29)-[Lys(AF647)] is derived from glucagon, which is a peptide hormone secreted by alpha cells located in the islet of Langerhans region of the pancreas. Glucagon is an essential catabolic hormone that is responsible for the regulation of blood glucose levels. Once released into the bloodstream, glucagon stimulates the production of hepatic glucose, which means it is considered to be a glucose-mobilizing agent. Excessive levels of glucagon can result in the development of hyperglycaemia, since the action of glucagon results in abnormally high blood glucose levels.This peptide contains AF647, structural analog to Alexa Fluor® 647 which is a widely used far-red fluorescent dye.Purezza:Min. 95%Colore e forma:PowderPeso molecolare:4,750 g/molLeu-Thr-Ile-Ile-Pro-Gln-Asp-Pro-Ile-Leu-Phe-Ser-Gl
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Formula:C82H136N20O23Peso molecolare:1,770.08 g/molClick Pip1
Delivery of peptide nucleic acid (PNA) oligonucleotides to targeted cells is becoming a viable therapeutic strategy by redirecting RNA splicing for conditions like Duchenne muscular dystrophy (DMD). The use of novel cell-penetrating peptides (CPP) has helped create targeted, and increased activity of the PNAs delivered.PNA internalization peptides (Pip) is a specifically designed CPP for conjugation to PNAs. Pips were designed to improve PNA activity observed in HeLa cells determined by splicing redirection assays and increased serum stability determined by mass spectrometry. Of the Pip series, Pip1 enters the cell in an energy-dependent manner, primarily via clathrin-dependent endocytosis. Pip1 conjugated to a PNA was determined to be well transported into the cell but is not the most stable against proteolysis. However, this may benefit some cargo depending on the intracellular destination. As a CPP for DMD, the proteolysis of Pip1 was deemed an issue but showed promise for other conjugates in HeLa cells.Pip1 is labelled at the N-terminus with an alkyne attachment for ease of reaction with an opposite Click reactive partner (azide). Azide-alkyne cycloaddition has become the most popular Click reaction. Alkyne-Pip1 allows various applications, particularly for protein conjugation, modification, and drug delivery.
Colore e forma:PowderPeso molecolare:3,243 g/molDOTA-Glu-[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2
DOTA-Glu-[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 is a trifunctional cyclic peptide that can be derivatized with various groups such as radiolabels. It has been shown to have strong affinity for the integrin receptor and can be used for targeting of tumors. DOTA-Glu-[Cyclo(Arg-Gly-Asp-D-Phe-Lys)]2 has also been found to inhibit cell proliferation and induce apoptosis in tumor cells.Formula:C75H113N23O23Purezza:Min. 95%Peso molecolare:1,704.88 g/molH-GGGGGC-NH2
Peptide H-GGGGGC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.hsBCL9CT-24
Blocks the Wnt pathway and inhibits the expression of TGFb1 in CT26 colon carcinoma cells, leading to the reduction of CCL20 and CCL22, two TGF-b- dependent chemokines critical for Treg cell recruitment into the tumour microenvironment. hsBCL9CT-24 shows robust antitumour efficacy across multiple in vivo models.
Purezza:Min. 95%Colore e forma:PowderPeso molecolare:1,629 g/molAngiotensin (Human, 1-7)
CAS:Angiotensin 1-7 (Ang-(1-7)) is a component of the renin angiotensin system RAS. Ang-(1-7) is produced by angiotensin-converting enzyme 2 (ACE2), from the angiotensin II (Ang-II) peptide, as well as by prolylendopeptidase (PEP) and neutral endopeptidase (NEP) which produce Ang-(1-7) directly from angiotensin I (Ang-I).Ang-(1-7) broadly opposes Ang-II actions. Ang-(1-7) has vasodilatory and anti-oxidative effects, and exerts protective actions in hypertension, diabetes, and other cardiovascular disorders, Ang-(1-7) therefore represents a promising therapeutic target for cardiovascular and metabolic diseases. Ang-(1-7) exerts its actions via its G-protein-coupled receptor, Mas. This novel arm of the RAS has effects that counterbalance those mediated by the classical ACE/Ang-II pathway.Formula:C41H62N12O11Purezza:Min. 95%Colore e forma:PowderPeso molecolare:899.01 g/molH-LLLASPR^-OH
Peptide H-LLLASPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Cyclo[Arg-Ala-Asp-D-Phe-Lys(Ac-SCH2CO)]
Cyclo[Arg-Ala-Asp-D-Phe-Lys(Ac-SCH2CO)] is a peptide that is derived by the sequential removal of amino acids from the C-terminal end of the RGD sequence. This peptide has been shown to interact with integrin αvβ3 and inhibit tumor cell proliferation and migration. Cyclo[Arg-Ala-Asp-D-Phe-Lys(Ac-SCH2CO)] also inhibits production of inflammatory cytokines by inhibiting NFκB signaling pathways.Formula:C32H47N9O9SPurezza:Min. 95%Peso molecolare:733.85 g/molH-IL^GG-NH2
Peptide H-IL^GG-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
HIV - 1 MN ENV - 176
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
Peso molecolare:1,658.9 g/molH-D-Val-Leu-Arg-AFC
This fluorogenic substrate is commonly used to measure protease activity. When in the presence to the protease of interest, H-D-Val-Leu-Arg-AFC is cleaved by the enzyme and a fluorescent compound is released. The amount of substrate cleaved is proportional to fluorescence increase, enabling the protease activity to be quantified. This makes H-D-Val-Leu-Arg-AFC perfect for use in investigating the activity and function of protease enzymes such as kallikrein. Specifically, it can be used in biochemical research as a fluorescent indicator of proteolysis and peptide release by kallikrein (excitation wavelength 400 nm and emission wavelength 505 nm).
Formula:C27H38F3N7O5Purezza:Min. 95%Peso molecolare:597.64 g/molAc-KVPRNQDWL-OH
Peptide Ac-KVPRNQDWL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-ELYETASELPR^-OH
Peptide H-ELYETASELPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
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