Fmoc-Glu-allyl ester

CAS: 144120-54-7

Rif. 01-4026433

Informazioni sul prodotto

• Nome: Fmoc-Glu-allyl ester
• Sinonimi: Fmoc-Glu-OAll
• Marchio: Bachem
• Descrizione: α-Allyl esters are of special interest, because they are a useful tool for the on-resin synthesis of head-to-tail cyclic peptides, side-chain lactam peptides, glyco- and sulfo-peptides, and branched peptides. Allyl esters are cleaved quantitatively under mild conditions using Pd(0). These conditions are compatible with Fmoc- and Boc-SPPS. Fmoc-Glu-OAll is a versatile educt for the synthesis of N-modified glutamines. Due to the lack of steric hindrance of the allyl group, prolonged treatment with harsher Fmoc cleavage agents or even piperidine may induce side-reactions as glutarimide formation, as observed by Zhu and Marchant.

Proprietà chimiche

• Peso molecolare: 409.44
• Formula: C₂₃H₂₃NO₆
• Purezza: 99.03%
• Colore/Forma: White Powder